1 Data Description

References: Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.

Data source:
FireBrowse TCGA BRCA Archives.

Samples:
TCGA breast invasive carcinoma (BRCA) tumor samples in file “illuminahiseq_rnaseqv2-RSEM_genes_normalized”.
To avoid possible confounding due to gender and race, we confined our study samples to be only from female Caucasian subjects.
In addition, only samples with somatic mutation annotation were kept, resulted in 700 samples.

Genes:
Only the top 10k variable genes in samples of consideration were kept.

Normalization:
log2(RSEM normalized counts) corrected for subject age and tumor purity. The corrected and scaled expression data were used as input for subsequent factor analysis.

Perturbations:
Somatic mutation status of selected frequently mutated driver genes (TP53, CDH1, GATA3, MAP3K1, PIK3CA).
Mutations were classified into 2 types: missense mutations and loss of function (LOF) mutations.

Number of samples that harbor each type of mutation (out of all 700)
Mutation	TP53_LOF	TP53_mis	CDH1_LOF	CDH1_mis	GATA3_LOF
Num_cells	78	113	73	11	63
Mutation	GATA3_mis	MAP3K1_LOF	MAP3K1_mis	PIK3CA_LOF	PIK3CA_mis
Num_cells	7	43	11	8	226

2 Guided results

Here, our “guide”, \(G\) matrix, consists of the somatic mutation status (missense and LOF separated) of top 5 driver genes across samples.

We specified 20 factors in our model. In each case, Gibbs sampling was conducted for 2000 iterations, and the posterior mean estimates were averaged over the last 500 iterations.

2.1 SVD Initialization

2.1.1 Local False Sign Rate (LFSR)

For a given GSFA inference result, we can estimate the effect a certain KO condition \(m\) has on the expression of gene \(j\) by computing the LFSR of \(\beta_{m\cdot} \cdot W_{j\cdot}\).

GSFA, # of genes that passed LFSR cutoff of 0.05:
KO	TP53_LOF	TP53_mis	CDH1_LOF	CDH1_mis	GATA3_LOF
Num_genes	7124	6995	5262	0	2887
KO	GATA3_mis	MAP3K1_LOF	MAP3K1_mis	PIK3CA_LOF	PIK3CA_mis
Num_genes	0	52	0	0	6823

2.1.2 Factor ~ KO Beta PIP

2.1.3 Factor ~ KO Posterior Association

2.1.4 Beta PIP vs P-Value

2.1.5 Correlation btw Factors

3 Gene Ontology Enrichment Analysis

Statistical test: hypergeometric test;

GO category: Biological Process.

3.1 GO enrichment per factor

Target: Genes w/ PIP > 0.95 in each factor;
Backgroud: all 10000 genes used in factor analysis.

GO terms that passed over-representation test fold change \(\geq\) 1.5 and q value \(<\) 0.05:

Factor 2 : 14 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030198	GO:0030198	extracellular matrix organization	171/3409	264/8135	1.55	2.36e-14	1.05e-10	264
GO:0051216	GO:0051216	cartilage development	95/3409	148/8135	1.53	2.96e-08	3.04e-05	148
GO:0030199	GO:0030199	collagen fibril organization	29/3409	37/8135	1.87	6.54e-06	2.42e-03	37
GO:0002062	GO:0002062	chondrocyte differentiation	56/3409	86/8135	1.55	1.09e-05	3.01e-03	86
GO:0007272	GO:0007272	ensheathment of neurons	46/3409	71/8135	1.55	7.92e-05	1.41e-02	71
GO:0008366	GO:0008366	axon ensheathment	46/3409	71/8135	1.55	7.92e-05	1.41e-02	71
GO:0030728	GO:0030728	ovulation	13/3409	14/8135	2.22	1.04e-04	1.71e-02	14
GO:0042552	GO:0042552	myelination	45/3409	70/8135	1.53	1.24e-04	1.84e-02	70
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	23/3409	31/8135	1.77	2.66e-04	3.19e-02	31
GO:0051965	GO:0051965	positive regulation of synapse assembly	35/3409	53/8135	1.58	3.24e-04	3.51e-02	53
GO:0032835	GO:0032835	glomerulus development	30/3409	44/8135	1.63	3.75e-04	3.78e-02	44
GO:0061035	GO:0061035	regulation of cartilage development	31/3409	46/8135	1.61	4.14e-04	3.99e-02	46
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	34/3409	52/8135	1.56	5.20e-04	4.44e-02	52
GO:0090322	GO:0090322	regulation of superoxide metabolic process	16/3409	20/8135	1.91	5.87e-04	4.56e-02	20

Factor 3 : 4 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1905517	GO:1905517	macrophage migration	32/5002	34/8135	1.53	1.55e-05	0.00832	34
GO:0021532	GO:0021532	neural tube patterning	18/5002	18/8135	1.63	1.56e-04	0.02237	18
GO:1905521	GO:1905521	regulation of macrophage migration	22/5002	23/8135	1.56	2.10e-04	0.02776	23
GO:0048246	GO:0048246	macrophage chemotaxis	25/5002	27/8135	1.51	3.03e-04	0.03457	27

Factor 4 : 197 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030198	GO:0030198	extracellular matrix organization	177/2974	264/8135	1.83	1.65e-24	6.62e-21	264
GO:0043062	GO:0043062	extracellular structure organization	191/2974	300/8135	1.74	2.67e-22	5.36e-19	300
GO:0001501	GO:0001501	skeletal system development	201/2974	334/8135	1.65	3.14e-19	4.20e-16	334
GO:0001944	GO:0001944	vasculature development	236/2974	417/8135	1.55	1.09e-17	1.09e-14	417
GO:0072358	GO:0072358	cardiovascular system development	238/2974	422/8135	1.54	1.40e-17	1.12e-14	422
GO:0001568	GO:0001568	blood vessel development	228/2974	401/8135	1.56	1.93e-17	1.29e-14	401
GO:0048514	GO:0048514	blood vessel morphogenesis	198/2974	360/8135	1.50	2.55e-13	1.46e-10	360
GO:0001503	GO:0001503	ossification	141/2974	238/8135	1.62	4.66e-13	2.33e-10	238
GO:0001525	GO:0001525	angiogenesis	172/2974	306/8135	1.54	8.32e-13	3.33e-10	306
GO:0001649	GO:0001649	osteoblast differentiation	80/2974	121/8135	1.81	2.91e-11	8.97e-09	121
GO:0051216	GO:0051216	cartilage development	92/2974	148/8135	1.70	1.59e-10	3.99e-08	148
GO:0060485	GO:0060485	mesenchyme development	103/2974	171/8135	1.65	1.83e-10	4.30e-08	171
GO:0061448	GO:0061448	connective tissue development	106/2974	179/8135	1.62	4.05e-10	8.11e-08	179
GO:0030199	GO:0030199	collagen fibril organization	32/2974	37/8135	2.37	4.65e-10	8.87e-08	37
GO:0048762	GO:0048762	mesenchymal cell differentiation	81/2974	129/8135	1.72	9.93e-10	1.81e-07	129
GO:0030111	GO:0030111	regulation of Wnt signaling pathway	96/2974	163/8135	1.61	4.07e-09	6.27e-07	163
GO:0090287	GO:0090287	regulation of cellular response to growth factor stimulus	94/2974	159/8135	1.62	4.50e-09	6.69e-07	159
GO:0002062	GO:0002062	chondrocyte differentiation	58/2974	86/8135	1.84	5.05e-09	7.22e-07	86
GO:0090130	GO:0090130	tissue migration	89/2974	149/8135	1.63	5.72e-09	7.91e-07	149
GO:0048705	GO:0048705	skeletal system morphogenesis	95/2974	162/8135	1.60	6.68e-09	8.92e-07	162
GO:0060070	GO:0060070	canonical Wnt signaling pathway	92/2974	157/8135	1.60	1.22e-08	1.52e-06	157
GO:0030178	GO:0030178	negative regulation of Wnt signaling pathway	63/2974	98/8135	1.76	1.95e-08	2.36e-06	98
GO:0010631	GO:0010631	epithelial cell migration	84/2974	142/8135	1.62	2.88e-08	3.31e-06	142
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	74/2974	122/8135	1.66	4.47e-08	4.62e-06	122
GO:0090132	GO:0090132	epithelium migration	84/2974	143/8135	1.61	4.50e-08	4.62e-06	143
GO:0045667	GO:0045667	regulation of osteoblast differentiation	48/2974	70/8135	1.88	4.77e-08	4.78e-06	70
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	51/2974	76/8135	1.84	5.51e-08	5.26e-06	76
GO:0010632	GO:0010632	regulation of epithelial cell migration	67/2974	109/8135	1.68	9.34e-08	8.10e-06	109
GO:0060348	GO:0060348	bone development	79/2974	135/8135	1.60	1.42e-07	1.16e-05	135
GO:0048706	GO:0048706	embryonic skeletal system development	58/2974	92/8135	1.72	1.95e-07	1.56e-05	92
GO:0071559	GO:0071559	response to transforming growth factor beta	75/2974	128/8135	1.60	2.72e-07	2.10e-05	128
GO:0043542	GO:0043542	endothelial cell migration	61/2974	99/8135	1.69	3.10e-07	2.34e-05	99
GO:0090288	GO:0090288	negative regulation of cellular response to growth factor stimulus	55/2974	87/8135	1.73	3.52e-07	2.57e-05	87
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	37/2974	52/8135	1.95	3.89e-07	2.78e-05	52
GO:0001837	GO:0001837	epithelial to mesenchymal transition	49/2974	76/8135	1.76	6.46e-07	4.39e-05	76
GO:0090090	GO:0090090	negative regulation of canonical Wnt signaling pathway	50/2974	79/8135	1.73	1.14e-06	7.48e-05	79
GO:0071560	GO:0071560	cellular response to transforming growth factor beta stimulus	71/2974	123/8135	1.58	1.23e-06	7.98e-05	123
GO:0072132	GO:0072132	mesenchyme morphogenesis	28/2974	37/8135	2.07	1.38e-06	8.50e-05	37
GO:0042476	GO:0042476	odontogenesis	57/2974	94/8135	1.66	1.59e-06	9.66e-05	94
GO:0090101	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	45/2974	70/8135	1.76	2.08e-06	1.23e-04	70
GO:0003170	GO:0003170	heart valve development	27/2974	36/8135	2.05	2.89e-06	1.65e-04	36
GO:1904018	GO:1904018	positive regulation of vasculature development	68/2974	119/8135	1.56	3.38e-06	1.88e-04	119
GO:0010594	GO:0010594	regulation of endothelial cell migration	47/2974	75/8135	1.71	3.57e-06	1.96e-04	75
GO:0060021	GO:0060021	roof of mouth development	39/2974	59/8135	1.81	3.62e-06	1.96e-04	59
GO:0045766	GO:0045766	positive regulation of angiogenesis	62/2974	107/8135	1.58	4.86e-06	2.56e-04	107
GO:0061035	GO:0061035	regulation of cartilage development	32/2974	46/8135	1.90	5.25e-06	2.73e-04	46
GO:0090092	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	77/2974	140/8135	1.50	5.68e-06	2.85e-04	140
GO:0030323	GO:0030323	respiratory tube development	64/2974	112/8135	1.56	6.52e-06	3.06e-04	112
GO:0022617	GO:0022617	extracellular matrix disassembly	37/2974	56/8135	1.81	6.53e-06	3.06e-04	56
GO:0032963	GO:0032963	collagen metabolic process	43/2974	68/8135	1.73	6.59e-06	3.06e-04	68
GO:0002063	GO:0002063	chondrocyte development	27/2974	37/8135	2.00	6.96e-06	3.17e-04	37
GO:0030278	GO:0030278	regulation of ossification	68/2974	121/8135	1.54	7.43e-06	3.35e-04	121
GO:0060541	GO:0060541	respiratory system development	71/2974	128/8135	1.52	8.77e-06	3.91e-04	128
GO:0030324	GO:0030324	lung development	63/2974	111/8135	1.55	1.04e-05	4.42e-04	111
GO:0003281	GO:0003281	ventricular septum development	32/2974	47/8135	1.86	1.07e-05	4.51e-04	47
GO:0048704	GO:0048704	embryonic skeletal system morphogenesis	43/2974	69/8135	1.70	1.13e-05	4.58e-04	69
GO:0003279	GO:0003279	cardiac septum development	42/2974	67/8135	1.71	1.16e-05	4.60e-04	67
GO:0002040	GO:0002040	sprouting angiogenesis	41/2974	65/8135	1.73	1.18e-05	4.64e-04	65
GO:0017015	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	37/2974	57/8135	1.78	1.21e-05	4.70e-04	57
GO:0060349	GO:0060349	bone morphogenesis	48/2974	80/8135	1.64	1.57e-05	6.01e-04	80
GO:0060412	GO:0060412	ventricular septum morphogenesis	22/2974	29/8135	2.08	1.83e-05	6.84e-04	29
GO:0061437	GO:0061437	renal system vasculature development	13/2974	14/8135	2.54	1.90e-05	6.85e-04	14
GO:0061440	GO:0061440	kidney vasculature development	13/2974	14/8135	2.54	1.90e-05	6.85e-04	14
GO:0072012	GO:0072012	glomerulus vasculature development	13/2974	14/8135	2.54	1.90e-05	6.85e-04	14
GO:1903844	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	37/2974	58/8135	1.74	2.17e-05	7.56e-04	58
GO:0003179	GO:0003179	heart valve morphogenesis	24/2974	33/8135	1.99	2.51e-05	8.61e-04	33
GO:0030512	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	26/2974	37/8135	1.92	3.09e-05	1.03e-03	37
GO:0006024	GO:0006024	glycosaminoglycan biosynthetic process	40/2974	65/8135	1.68	3.49e-05	1.14e-03	65
GO:0022612	GO:0022612	gland morphogenesis	50/2974	86/8135	1.59	3.50e-05	1.14e-03	86
GO:0003158	GO:0003158	endothelium development	37/2974	59/8135	1.72	3.78e-05	1.22e-03	59
GO:0060840	GO:0060840	artery development	32/2974	49/8135	1.79	3.92e-05	1.26e-03	49
GO:0003205	GO:0003205	cardiac chamber development	60/2974	108/8135	1.52	4.02e-05	1.27e-03	108
GO:0060317	GO:0060317	cardiac epithelial to mesenchymal transition	17/2974	21/8135	2.21	4.03e-05	1.27e-03	21
GO:0030574	GO:0030574	collagen catabolic process	23/2974	32/8135	1.97	5.07e-05	1.59e-03	32
GO:1905314	GO:1905314	semi-lunar valve development	18/2974	23/8135	2.14	5.38e-05	1.66e-03	23
GO:0006023	GO:0006023	aminoglycan biosynthetic process	41/2974	68/8135	1.65	5.53e-05	1.68e-03	68
GO:0045669	GO:0045669	positive regulation of osteoblast differentiation	25/2974	36/8135	1.90	6.03e-05	1.79e-03	36
GO:0035107	GO:0035107	appendage morphogenesis	54/2974	96/8135	1.54	6.12e-05	1.79e-03	96
GO:0035108	GO:0035108	limb morphogenesis	54/2974	96/8135	1.54	6.12e-05	1.79e-03	96
GO:1903845	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	26/2974	38/8135	1.87	6.39e-05	1.84e-03	38
GO:0010717	GO:0010717	regulation of epithelial to mesenchymal transition	30/2974	46/8135	1.78	7.10e-05	1.98e-03	46
GO:0007179	GO:0007179	transforming growth factor beta receptor signaling pathway	51/2974	90/8135	1.55	7.49e-05	2.03e-03	90
GO:0003231	GO:0003231	cardiac ventricle development	48/2974	84/8135	1.56	9.11e-05	2.30e-03	84
GO:0042733	GO:0042733	embryonic digit morphogenesis	21/2974	29/8135	1.98	9.12e-05	2.30e-03	29
GO:0032330	GO:0032330	regulation of chondrocyte differentiation	24/2974	35/8135	1.88	1.16e-04	2.84e-03	35
GO:0035329	GO:0035329	hippo signaling	11/2974	12/8135	2.51	1.23e-04	2.97e-03	12
GO:0060411	GO:0060411	cardiac septum morphogenesis	32/2974	51/8135	1.72	1.24e-04	2.97e-03	51
GO:0003203	GO:0003203	endocardial cushion morphogenesis	18/2974	24/8135	2.05	1.42e-04	3.36e-03	24
GO:0071526	GO:0071526	semaphorin-plexin signaling pathway	18/2974	24/8135	2.05	1.42e-04	3.36e-03	24
GO:0043392	GO:0043392	negative regulation of DNA binding	19/2974	26/8135	2.00	1.64e-04	3.84e-03	26
GO:0010977	GO:0010977	negative regulation of neuron projection development	50/2974	90/8135	1.52	1.73e-04	3.98e-03	90
GO:0042310	GO:0042310	vasoconstriction	36/2974	60/8135	1.64	1.79e-04	4.10e-03	60
GO:0003197	GO:0003197	endocardial cushion development	21/2974	30/8135	1.91	1.99e-04	4.46e-03	30
GO:0010906	GO:0010906	regulation of glucose metabolic process	32/2974	52/8135	1.68	2.10e-04	4.65e-03	52
GO:0045446	GO:0045446	endothelial cell differentiation	32/2974	52/8135	1.68	2.10e-04	4.65e-03	52
GO:0003177	GO:0003177	pulmonary valve development	12/2974	14/8135	2.34	2.25e-04	4.91e-03	14
GO:0003181	GO:0003181	atrioventricular valve morphogenesis	12/2974	14/8135	2.34	2.25e-04	4.91e-03	14
GO:0030326	GO:0030326	embryonic limb morphogenesis	45/2974	80/8135	1.54	2.46e-04	5.27e-03	80
GO:0035113	GO:0035113	embryonic appendage morphogenesis	45/2974	80/8135	1.54	2.46e-04	5.27e-03	80
GO:0097756	GO:0097756	negative regulation of blood vessel diameter	37/2974	63/8135	1.61	2.69e-04	5.74e-03	63
GO:0051100	GO:0051100	negative regulation of binding	43/2974	76/8135	1.55	2.82e-04	5.86e-03	76
GO:0014033	GO:0014033	neural crest cell differentiation	34/2974	57/8135	1.63	3.15e-04	6.51e-03	57
GO:0014031	GO:0014031	mesenchymal cell development	33/2974	55/8135	1.64	3.30e-04	6.76e-03	55
GO:0003171	GO:0003171	atrioventricular valve development	13/2974	16/8135	2.22	3.33e-04	6.76e-03	16
GO:0006939	GO:0006939	smooth muscle contraction	46/2974	83/8135	1.52	3.34e-04	6.76e-03	83
GO:0045778	GO:0045778	positive regulation of ossification	32/2974	53/8135	1.65	3.45e-04	6.89e-03	53
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	19/2974	27/8135	1.92	3.64e-04	7.15e-03	27
GO:0014812	GO:0014812	muscle cell migration	29/2974	47/8135	1.69	3.88e-04	7.48e-03	47
GO:0001885	GO:0001885	endothelial cell development	20/2974	29/8135	1.89	3.88e-04	7.48e-03	29
GO:0035904	GO:0035904	aorta development	20/2974	29/8135	1.89	3.88e-04	7.48e-03	29
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	21/2974	31/8135	1.85	4.06e-04	7.71e-03	31
GO:0048566	GO:0048566	embryonic digestive tract development	21/2974	31/8135	1.85	4.06e-04	7.71e-03	31
GO:0043255	GO:0043255	regulation of carbohydrate biosynthetic process	27/2974	43/8135	1.72	4.10e-04	7.75e-03	43
GO:0048146	GO:0048146	positive regulation of fibroblast proliferation	22/2974	33/8135	1.82	4.17e-04	7.81e-03	33
GO:0014909	GO:0014909	smooth muscle cell migration	25/2974	39/8135	1.75	4.23e-04	7.82e-03	39
GO:0032092	GO:0032092	positive regulation of protein binding	23/2974	35/8135	1.80	4.24e-04	7.82e-03	35
GO:0060325	GO:0060325	face morphogenesis	14/2974	18/8135	2.13	4.36e-04	7.98e-03	18
GO:0061028	GO:0061028	establishment of endothelial barrier	14/2974	18/8135	2.13	4.36e-04	7.98e-03	18
GO:0003151	GO:0003151	outflow tract morphogenesis	33/2974	56/8135	1.61	5.24e-04	9.51e-03	56
GO:0002089	GO:0002089	lens morphogenesis in camera-type eye	11/2974	13/8135	2.31	5.33e-04	9.59e-03	13
GO:0003184	GO:0003184	pulmonary valve morphogenesis	11/2974	13/8135	2.31	5.33e-04	9.59e-03	13
GO:0014032	GO:0014032	neural crest cell development	31/2974	52/8135	1.63	5.82e-04	1.03e-02	52
GO:0043534	GO:0043534	blood vessel endothelial cell migration	31/2974	52/8135	1.63	5.82e-04	1.03e-02	52
GO:0060350	GO:0060350	endochondral bone morphogenesis	31/2974	52/8135	1.63	5.82e-04	1.03e-02	52
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	16/2974	22/8135	1.99	6.05e-04	1.06e-02	22
GO:0061037	GO:0061037	negative regulation of cartilage development	16/2974	22/8135	1.99	6.05e-04	1.06e-02	22
GO:0042475	GO:0042475	odontogenesis of dentin-containing tooth	36/2974	63/8135	1.56	6.71e-04	1.15e-02	63
GO:0030705	GO:0030705	cytoskeleton-dependent intracellular transport	27/2974	44/8135	1.68	6.94e-04	1.17e-02	44
GO:0045668	GO:0045668	negative regulation of osteoblast differentiation	19/2974	28/8135	1.86	7.45e-04	1.25e-02	28
GO:0051099	GO:0051099	positive regulation of binding	40/2974	72/8135	1.52	7.50e-04	1.25e-02	72
GO:0060973	GO:0060973	cell migration involved in heart development	12/2974	15/8135	2.19	7.50e-04	1.25e-02	15
GO:0010463	GO:0010463	mesenchymal cell proliferation	24/2974	38/8135	1.73	7.57e-04	1.25e-02	38
GO:0050919	GO:0050919	negative chemotaxis	20/2974	30/8135	1.82	7.65e-04	1.26e-02	30
GO:0003198	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	9/2974	10/8135	2.46	7.77e-04	1.27e-02	10
GO:0051101	GO:0051101	regulation of DNA binding	33/2974	57/8135	1.58	8.12e-04	1.32e-02	57
GO:0030279	GO:0030279	negative regulation of ossification	27/2974	45/8135	1.64	1.13e-03	1.78e-02	45
GO:0005978	GO:0005978	glycogen biosynthetic process	15/2974	21/8135	1.95	1.22e-03	1.89e-02	21
GO:0009250	GO:0009250	glucan biosynthetic process	15/2974	21/8135	1.95	1.22e-03	1.89e-02	21
GO:0010675	GO:0010675	regulation of cellular carbohydrate metabolic process	38/2974	69/8135	1.51	1.26e-03	1.92e-02	69
GO:0015980	GO:0015980	energy derivation by oxidation of organic compounds	38/2974	69/8135	1.51	1.26e-03	1.92e-02	69
GO:0060324	GO:0060324	face development	17/2974	25/8135	1.86	1.37e-03	2.05e-02	25
GO:0033692	GO:0033692	cellular polysaccharide biosynthetic process	21/2974	33/8135	1.74	1.40e-03	2.07e-02	33
GO:1905207	GO:1905207	regulation of cardiocyte differentiation	21/2974	33/8135	1.74	1.40e-03	2.07e-02	33
GO:0009954	GO:0009954	proximal/distal pattern formation	19/2974	29/8135	1.79	1.42e-03	2.09e-02	29
GO:0010718	GO:0010718	positive regulation of epithelial to mesenchymal transition	19/2974	29/8135	1.79	1.42e-03	2.09e-02	29
GO:0003272	GO:0003272	endocardial cushion formation	12/2974	16/8135	2.05	2.00e-03	2.75e-02	16
GO:0006929	GO:0006929	substrate-dependent cell migration	12/2974	16/8135	2.05	2.00e-03	2.75e-02	16
GO:0032331	GO:0032331	negative regulation of chondrocyte differentiation	12/2974	16/8135	2.05	2.00e-03	2.75e-02	16
GO:1903010	GO:1903010	regulation of bone development	12/2974	16/8135	2.05	2.00e-03	2.75e-02	16
GO:0002088	GO:0002088	lens development in camera-type eye	25/2974	42/8135	1.63	2.01e-03	2.76e-02	42
GO:0048864	GO:0048864	stem cell development	31/2974	55/8135	1.54	2.10e-03	2.86e-02	55
GO:0016339	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	24/2974	40/8135	1.64	2.12e-03	2.87e-02	40
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	23/2974	38/8135	1.66	2.22e-03	2.99e-02	38
GO:0048844	GO:0048844	artery morphogenesis	23/2974	38/8135	1.66	2.22e-03	2.99e-02	38
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	30/2974	53/8135	1.55	2.26e-03	3.03e-02	53
GO:0014910	GO:0014910	regulation of smooth muscle cell migration	22/2974	36/8135	1.67	2.32e-03	3.08e-02	36
GO:0060351	GO:0060351	cartilage development involved in endochondral bone morphogenesis	22/2974	36/8135	1.67	2.32e-03	3.08e-02	36
GO:0000271	GO:0000271	polysaccharide biosynthetic process	21/2974	34/8135	1.69	2.41e-03	3.18e-02	34
GO:0003209	GO:0003209	cardiac atrium morphogenesis	14/2974	20/8135	1.91	2.43e-03	3.19e-02	20
GO:0060323	GO:0060323	head morphogenesis	14/2974	20/8135	1.91	2.43e-03	3.19e-02	20
GO:0007224	GO:0007224	smoothened signaling pathway	34/2974	62/8135	1.50	2.45e-03	3.19e-02	62
GO:0003156	GO:0003156	regulation of animal organ formation	20/2974	32/8135	1.71	2.49e-03	3.22e-02	32
GO:0003230	GO:0003230	cardiac atrium development	15/2974	22/8135	1.87	2.55e-03	3.22e-02	22
GO:0040036	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	15/2974	22/8135	1.87	2.55e-03	3.22e-02	22
GO:0099068	GO:0099068	postsynapse assembly	18/2974	28/8135	1.76	2.61e-03	3.28e-02	28
GO:0005979	GO:0005979	regulation of glycogen biosynthetic process	9/2974	11/8135	2.24	2.88e-03	3.52e-02	11
GO:0010934	GO:0010934	macrophage cytokine production	9/2974	11/8135	2.24	2.88e-03	3.52e-02	11
GO:0010962	GO:0010962	regulation of glucan biosynthetic process	9/2974	11/8135	2.24	2.88e-03	3.52e-02	11
GO:0036035	GO:0036035	osteoclast development	9/2974	11/8135	2.24	2.88e-03	3.52e-02	11
GO:0061162	GO:0061162	establishment of monopolar cell polarity	9/2974	11/8135	2.24	2.88e-03	3.52e-02	11
GO:0044264	GO:0044264	cellular polysaccharide metabolic process	26/2974	45/8135	1.58	2.96e-03	3.55e-02	45
GO:1903524	GO:1903524	positive regulation of blood circulation	31/2974	56/8135	1.51	3.08e-03	3.67e-02	56
GO:0001755	GO:0001755	neural crest cell migration	24/2974	41/8135	1.60	3.35e-03	3.93e-02	41
GO:0006112	GO:0006112	energy reserve metabolic process	24/2974	41/8135	1.60	3.35e-03	3.93e-02	41
GO:0008589	GO:0008589	regulation of smoothened signaling pathway	23/2974	39/8135	1.61	3.56e-03	4.10e-02	39
GO:1901888	GO:1901888	regulation of cell junction assembly	23/2974	39/8135	1.61	3.56e-03	4.10e-02	39
GO:0030516	GO:0030516	regulation of axon extension	29/2974	52/8135	1.53	3.58e-03	4.11e-02	52
GO:0032885	GO:0032885	regulation of polysaccharide biosynthetic process	10/2974	13/8135	2.10	3.63e-03	4.13e-02	13
GO:0040037	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	10/2974	13/8135	2.10	3.63e-03	4.13e-02	13
GO:1902547	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	10/2974	13/8135	2.10	3.63e-03	4.13e-02	13
GO:0010827	GO:0010827	regulation of glucose transmembrane transport	22/2974	37/8135	1.63	3.77e-03	4.25e-02	37
GO:2001022	GO:2001022	positive regulation of response to DNA damage stimulus	21/2974	35/8135	1.64	3.97e-03	4.41e-02	35
GO:0046847	GO:0046847	filopodium assembly	20/2974	33/8135	1.66	4.17e-03	4.58e-02	33
GO:0060425	GO:0060425	lung morphogenesis	20/2974	33/8135	1.66	4.17e-03	4.58e-02	33
GO:0006073	GO:0006073	cellular glucan metabolic process	19/2974	31/8135	1.68	4.36e-03	4.70e-02	31
GO:0044042	GO:0044042	glucan metabolic process	19/2974	31/8135	1.68	4.36e-03	4.70e-02	31
GO:0099072	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	19/2974	31/8135	1.68	4.36e-03	4.70e-02	31
GO:0007044	GO:0007044	cell-substrate junction assembly	26/2974	46/8135	1.55	4.46e-03	4.75e-02	46
GO:0003176	GO:0003176	aortic valve development	12/2974	17/8135	1.93	4.54e-03	4.80e-02	17
GO:0055025	GO:0055025	positive regulation of cardiac muscle tissue development	18/2974	29/8135	1.70	4.54e-03	4.80e-02	29
GO:0010171	GO:0010171	body morphogenesis	17/2974	27/8135	1.72	4.69e-03	4.88e-02	27
GO:0010464	GO:0010464	regulation of mesenchymal cell proliferation	17/2974	27/8135	1.72	4.69e-03	4.88e-02	27
GO:0048048	GO:0048048	embryonic eye morphogenesis	17/2974	27/8135	1.72	4.69e-03	4.88e-02	27
GO:0010907	GO:0010907	positive regulation of glucose metabolic process	13/2974	19/8135	1.87	4.76e-03	4.93e-02	19
GO:0032835	GO:0032835	glomerulus development	25/2974	44/8135	1.55	4.79e-03	4.93e-02	44
GO:0090263	GO:0090263	positive regulation of canonical Wnt signaling pathway	25/2974	44/8135	1.55	4.79e-03	4.93e-02	44
GO:0048008	GO:0048008	platelet-derived growth factor receptor signaling pathway	14/2974	21/8135	1.82	4.85e-03	4.96e-02	21

Factor 5 : 913 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0002263	GO:0002263	cell activation involved in immune response	171/1028	356/8135	3.80	1.33e-63	2.47e-60	356
GO:0002443	GO:0002443	leukocyte mediated immunity	185/1028	410/8135	3.57	1.50e-63	2.47e-60	410
GO:0002366	GO:0002366	leukocyte activation involved in immune response	170/1028	354/8135	3.80	3.39e-63	3.73e-60	354
GO:0046649	GO:0046649	lymphocyte activation	180/1028	397/8135	3.59	3.75e-62	3.09e-59	397
GO:0042110	GO:0042110	T cell activation	143/1028	285/8135	3.97	6.24e-56	4.12e-53	285
GO:0002274	GO:0002274	myeloid leukocyte activation	153/1028	328/8135	3.69	1.59e-54	8.73e-52	328
GO:0050865	GO:0050865	regulation of cell activation	156/1028	344/8135	3.59	1.45e-53	6.85e-51	344
GO:0045087	GO:0045087	innate immune response	190/1028	485/8135	3.10	1.97e-53	8.12e-51	485
GO:0002694	GO:0002694	regulation of leukocyte activation	148/1028	316/8135	3.71	5.63e-53	2.06e-50	316
GO:0002250	GO:0002250	adaptive immune response	133/1028	269/8135	3.91	5.72e-51	1.89e-48	269
GO:0050778	GO:0050778	positive regulation of immune response	171/1028	423/8135	3.20	4.05e-50	1.22e-47	423
GO:0051249	GO:0051249	regulation of lymphocyte activation	125/1028	260/8135	3.80	3.74e-46	1.03e-43	260
GO:0043299	GO:0043299	leukocyte degranulation	123/1028	254/8135	3.83	7.79e-46	1.98e-43	254
GO:0050863	GO:0050863	regulation of T cell activation	108/1028	203/8135	4.21	2.70e-45	6.36e-43	203
GO:0001816	GO:0001816	cytokine production	169/1028	444/8135	3.01	3.17e-45	6.97e-43	444
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	124/1028	261/8135	3.76	4.49e-45	9.26e-43	261
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	123/1028	262/8135	3.72	5.20e-44	1.01e-41	262
GO:0002764	GO:0002764	immune response-regulating signaling pathway	125/1028	270/8135	3.66	6.51e-44	1.19e-41	270
GO:0050867	GO:0050867	positive regulation of cell activation	107/1028	210/8135	4.03	1.61e-42	2.79e-40	210
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	109/1028	218/8135	3.96	2.72e-42	4.48e-40	218
GO:0002696	GO:0002696	positive regulation of leukocyte activation	104/1028	202/8135	4.07	7.14e-42	1.12e-39	202
GO:0002757	GO:0002757	immune response-activating signal transduction	116/1028	249/8135	3.69	4.58e-41	6.87e-39	249
GO:0002521	GO:0002521	leukocyte differentiation	133/1028	318/8135	3.31	1.19e-40	1.71e-38	318
GO:0036230	GO:0036230	granulocyte activation	111/1028	233/8135	3.77	1.83e-40	2.52e-38	233
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	100/1028	196/8135	4.04	8.23e-40	1.09e-37	196
GO:0042119	GO:0042119	neutrophil activation	109/1028	230/8135	3.75	1.83e-39	2.33e-37	230
GO:0002253	GO:0002253	activation of immune response	127/1028	302/8135	3.33	4.27e-39	5.22e-37	302
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	97/1028	189/8135	4.06	6.53e-39	7.70e-37	189
GO:0001817	GO:0001817	regulation of cytokine production	151/1028	406/8135	2.94	7.85e-39	8.94e-37	406
GO:0002283	GO:0002283	neutrophil activation involved in immune response	105/1028	222/8135	3.74	6.42e-38	7.06e-36	222
GO:0043312	GO:0043312	neutrophil degranulation	104/1028	219/8135	3.76	9.30e-38	9.90e-36	219
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	90/1028	170/8135	4.19	1.50e-37	1.55e-35	170
GO:0050870	GO:0050870	positive regulation of T cell activation	80/1028	139/8135	4.55	5.49e-37	5.49e-35	139
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	83/1028	149/8135	4.41	6.97e-37	6.77e-35	149
GO:0002446	GO:0002446	neutrophil mediated immunity	104/1028	227/8135	3.63	5.22e-36	4.92e-34	227
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	87/1028	167/8135	4.12	1.34e-35	1.23e-33	167
GO:0031347	GO:0031347	regulation of defense response	148/1028	425/8135	2.76	3.26e-34	2.91e-32	425
GO:0001819	GO:0001819	positive regulation of cytokine production	112/1028	271/8135	3.27	1.29e-33	1.12e-31	271
GO:0050900	GO:0050900	leukocyte migration	119/1028	306/8135	3.08	1.15e-32	9.76e-31	306
GO:0030097	GO:0030097	hemopoiesis	151/1028	459/8135	2.60	1.07e-31	8.83e-30	459
GO:0006887	GO:0006887	exocytosis	152/1028	466/8135	2.58	1.95e-31	1.56e-29	466
GO:0045055	GO:0045055	regulated exocytosis	143/1028	423/8135	2.68	1.98e-31	1.56e-29	423
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	85/1028	177/8135	3.80	2.18e-31	1.67e-29	177
GO:0032943	GO:0032943	mononuclear cell proliferation	85/1028	179/8135	3.76	6.19e-31	4.64e-29	179
GO:0030098	GO:0030098	lymphocyte differentiation	94/1028	214/8135	3.48	8.89e-31	6.52e-29	214
GO:0046651	GO:0046651	lymphocyte proliferation	84/1028	177/8135	3.76	1.48e-30	1.06e-28	177
GO:0022407	GO:0022407	regulation of cell-cell adhesion	105/1028	260/8135	3.20	1.71e-30	1.20e-28	260
GO:0070661	GO:0070661	leukocyte proliferation	88/1028	193/8135	3.61	2.44e-30	1.68e-28	193
GO:0048534	GO:0048534	hematopoietic or lymphoid organ development	154/1028	487/8135	2.50	3.88e-30	2.61e-28	487
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	147/1028	459/8135	2.53	2.09e-29	1.38e-27	459
GO:0070663	GO:0070663	regulation of leukocyte proliferation	77/1028	158/8135	3.86	4.80e-29	3.11e-27	158
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	75/1028	151/8135	3.93	5.30e-29	3.36e-27	151
GO:0030155	GO:0030155	regulation of cell adhesion	137/1028	419/8135	2.59	2.08e-28	1.30e-26	419
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	74/1028	150/8135	3.90	2.21e-28	1.35e-26	150
GO:0030217	GO:0030217	T cell differentiation	73/1028	151/8135	3.83	2.68e-27	1.61e-25	151
GO:0042098	GO:0042098	T cell proliferation	64/1028	120/8135	4.22	3.65e-27	2.15e-25	120
GO:0045785	GO:0045785	positive regulation of cell adhesion	100/1028	262/8135	3.02	1.00e-26	5.81e-25	262
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	59/1028	108/8135	4.32	7.41e-26	4.22e-24	108
GO:1902105	GO:1902105	regulation of leukocyte differentiation	77/1028	175/8135	3.48	2.14e-25	1.20e-23	175
GO:0006909	GO:0006909	phagocytosis	63/1028	126/8135	3.96	1.02e-24	5.64e-23	126
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	57/1028	106/8135	4.26	1.51e-24	8.16e-23	106
GO:0002697	GO:0002697	regulation of immune effector process	94/1028	251/8135	2.96	1.94e-24	1.03e-22	251
GO:0042102	GO:0042102	positive regulation of T cell proliferation	47/1028	76/8135	4.89	4.94e-24	2.59e-22	76
GO:0042129	GO:0042129	regulation of T cell proliferation	57/1028	108/8135	4.18	5.31e-24	2.74e-22	108
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	73/1028	168/8135	3.44	1.02e-23	5.19e-22	168
GO:0031349	GO:0031349	positive regulation of defense response	94/1028	257/8135	2.89	1.46e-23	7.31e-22	257
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	55/1028	103/8135	4.23	1.58e-23	7.81e-22	103
GO:0002683	GO:0002683	negative regulation of immune system process	97/1028	273/8135	2.81	3.34e-23	1.62e-21	273
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	63/1028	133/8135	3.75	4.40e-23	2.11e-21	133
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	54/1028	102/8135	4.19	7.00e-23	3.30e-21	102
GO:0002449	GO:0002449	lymphocyte mediated immunity	70/1028	161/8135	3.44	8.44e-23	3.92e-21	161
GO:0046631	GO:0046631	alpha-beta T cell activation	51/1028	93/8135	4.34	1.33e-22	6.09e-21	93
GO:0030595	GO:0030595	leukocyte chemotaxis	72/1028	170/8135	3.35	1.35e-22	6.09e-21	170
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	54/1028	104/8135	4.11	2.38e-22	1.06e-20	104
GO:0045088	GO:0045088	regulation of innate immune response	78/1028	198/8135	3.12	5.17e-22	2.28e-20	198
GO:0097529	GO:0097529	myeloid leukocyte migration	67/1028	154/8135	3.44	6.93e-22	3.01e-20	154
GO:0050852	GO:0050852	T cell receptor signaling pathway	46/1028	80/8135	4.55	1.15e-21	4.93e-20	80
GO:0060326	GO:0060326	cell chemotaxis	82/1028	221/8135	2.94	4.09e-21	1.73e-19	221
GO:0002699	GO:0002699	positive regulation of immune effector process	61/1028	140/8135	3.45	4.62e-20	1.93e-18	140
GO:0032103	GO:0032103	positive regulation of response to external stimulus	77/1028	208/8135	2.93	8.17e-20	3.37e-18	208
GO:0034341	GO:0034341	response to interferon-gamma	57/1028	126/8135	3.58	8.87e-20	3.62e-18	126
GO:0050663	GO:0050663	cytokine secretion	61/1028	145/8135	3.33	3.97e-19	1.60e-17	145
GO:0045580	GO:0045580	regulation of T cell differentiation	46/1028	89/8135	4.09	4.15e-19	1.65e-17	89
GO:1903706	GO:1903706	regulation of hemopoiesis	83/1028	241/8135	2.73	5.48e-19	2.15e-17	241
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	51/1028	108/8135	3.74	7.91e-19	3.07e-17	108
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	38/1028	64/8135	4.70	8.82e-19	3.38e-17	64
GO:0038093	GO:0038093	Fc receptor signaling pathway	34/1028	54/8135	4.98	4.47e-18	1.69e-16	54
GO:0050866	GO:0050866	negative regulation of cell activation	54/1028	123/8135	3.47	4.50e-18	1.69e-16	123
GO:0002695	GO:0002695	negative regulation of leukocyte activation	50/1028	108/8135	3.66	5.05e-18	1.87e-16	108
GO:0045089	GO:0045089	positive regulation of innate immune response	65/1028	169/8135	3.04	7.04e-18	2.58e-16	169
GO:0002685	GO:0002685	regulation of leukocyte migration	56/1028	132/8135	3.36	7.38e-18	2.68e-16	132
GO:0002286	GO:0002286	T cell activation involved in immune response	37/1028	64/8135	4.57	8.93e-18	3.20e-16	64
GO:0050727	GO:0050727	regulation of inflammatory response	83/1028	251/8135	2.62	9.49e-18	3.37e-16	251
GO:0009617	GO:0009617	response to bacterium	112/1028	398/8135	2.23	1.54e-17	5.40e-16	398
GO:0006897	GO:0006897	endocytosis	104/1028	357/8135	2.31	1.71e-17	5.94e-16	357
GO:0071346	GO:0071346	cellular response to interferon-gamma	50/1028	112/8135	3.53	3.39e-17	1.16e-15	112
GO:0098657	GO:0098657	import into cell	120/1028	445/8135	2.13	3.72e-17	1.26e-15	445
GO:0002819	GO:0002819	regulation of adaptive immune response	48/1028	105/8135	3.62	4.50e-17	1.52e-15	105
GO:0042089	GO:0042089	cytokine biosynthetic process	40/1028	77/8135	4.11	7.02e-17	2.34e-15	77
GO:0042113	GO:0042113	B cell activation	55/1028	134/8135	3.25	8.78e-17	2.90e-15	134
GO:0042107	GO:0042107	cytokine metabolic process	40/1028	78/8135	4.06	1.27e-16	4.15e-15	78
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	43/1028	89/8135	3.82	1.57e-16	5.07e-15	89
GO:0098542	GO:0098542	defense response to other organism	84/1028	268/8135	2.48	2.32e-16	7.44e-15	268
GO:0050707	GO:0050707	regulation of cytokine secretion	53/1028	129/8135	3.25	3.07e-16	9.75e-15	129
GO:0002237	GO:0002237	response to molecule of bacterial origin	74/1028	222/8135	2.64	3.79e-16	1.19e-14	222
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	37/1028	70/8135	4.18	4.94e-16	1.52e-14	70
GO:0046632	GO:0046632	alpha-beta T cell differentiation	37/1028	70/8135	4.18	4.94e-16	1.52e-14	70
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	44/1028	95/8135	3.67	5.11e-16	1.56e-14	95
GO:0071674	GO:0071674	mononuclear cell migration	36/1028	67/8135	4.25	6.18e-16	1.86e-14	67
GO:0032609	GO:0032609	interferon-gamma production	42/1028	88/8135	3.78	6.20e-16	1.86e-14	88
GO:0001818	GO:0001818	negative regulation of cytokine production	61/1028	165/8135	2.93	6.87e-16	2.04e-14	165
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	44/1028	96/8135	3.63	8.31e-16	2.45e-14	96
GO:0097530	GO:0097530	granulocyte migration	48/1028	112/8135	3.39	1.08e-15	3.16e-14	112
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	44/1028	98/8135	3.55	2.14e-15	6.20e-14	98
GO:0002218	GO:0002218	activation of innate immune response	52/1028	130/8135	3.17	2.26e-15	6.47e-14	130
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	28/1028	44/8135	5.04	2.78e-15	7.91e-14	44
GO:0071216	GO:0071216	cellular response to biotic stimulus	53/1028	135/8135	3.11	3.08e-15	8.69e-14	135
GO:0032496	GO:0032496	response to lipopolysaccharide	70/1028	213/8135	2.60	5.63e-15	1.57e-13	213
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	34/1028	64/8135	4.20	6.34e-15	1.76e-13	64
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	41/1028	90/8135	3.61	1.06e-14	2.88e-13	90
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	41/1028	90/8135	3.61	1.06e-14	2.88e-13	90
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	51/1028	130/8135	3.10	1.08e-14	2.91e-13	130
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	27/1028	43/8135	4.97	1.43e-14	3.85e-13	43
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	32/1028	59/8135	4.29	1.84e-14	4.89e-13	59
GO:0032649	GO:0032649	regulation of interferon-gamma production	38/1028	80/8135	3.76	1.87e-14	4.95e-13	80
GO:0071621	GO:0071621	granulocyte chemotaxis	44/1028	103/8135	3.38	1.99e-14	5.20e-13	103
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34/1028	66/8135	4.08	2.13e-14	5.53e-13	66
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	30/1028	53/8135	4.48	2.60e-14	6.70e-13	53
GO:0032623	GO:0032623	interleukin-2 production	26/1028	41/8135	5.02	3.15e-14	8.07e-13	41
GO:0002292	GO:0002292	T cell differentiation involved in immune response	27/1028	44/8135	4.86	3.27e-14	8.30e-13	44
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	39/1028	85/8135	3.63	3.56e-14	8.96e-13	85
GO:0002758	GO:0002758	innate immune response-activating signal transduction	49/1028	125/8135	3.10	3.76e-14	9.39e-13	125
GO:0050868	GO:0050868	negative regulation of T cell activation	34/1028	67/8135	4.02	3.80e-14	9.44e-13	67
GO:0045582	GO:0045582	positive regulation of T cell differentiation	31/1028	57/8135	4.30	4.28e-14	1.05e-12	57
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	36/1028	75/8135	3.80	6.14e-14	1.50e-12	75
GO:0071887	GO:0071887	leukocyte apoptotic process	34/1028	68/8135	3.96	6.70e-14	1.63e-12	68
GO:0002821	GO:0002821	positive regulation of adaptive immune response	34/1028	69/8135	3.90	1.16e-13	2.80e-12	69
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	32/1028	62/8135	4.08	1.17e-13	2.80e-12	62
GO:0002573	GO:0002573	myeloid leukocyte differentiation	49/1028	129/8135	3.01	1.57e-13	3.72e-12	129
GO:1990266	GO:1990266	neutrophil migration	41/1028	96/8135	3.38	1.58e-13	3.72e-12	96
GO:0050729	GO:0050729	positive regulation of inflammatory response	42/1028	100/8135	3.32	1.59e-13	3.73e-12	100
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	25/1028	40/8135	4.95	1.62e-13	3.75e-12	40
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	26/1028	43/8135	4.78	1.63e-13	3.75e-12	43
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	37/1028	81/8135	3.61	1.93e-13	4.41e-12	81
GO:0051345	GO:0051345	positive regulation of hydrolase activity	95/1028	356/8135	2.11	1.94e-13	4.41e-12	356
GO:1903708	GO:1903708	positive regulation of hemopoiesis	45/1028	113/8135	3.15	2.16e-13	4.89e-12	113
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	28/1028	50/8135	4.43	2.77e-13	6.21e-12	50
GO:0032640	GO:0032640	tumor necrosis factor production	38/1028	86/8135	3.50	3.35e-13	7.42e-12	86
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	38/1028	86/8135	3.50	3.35e-13	7.42e-12	86
GO:0030593	GO:0030593	neutrophil chemotaxis	39/1028	90/8135	3.43	3.53e-13	7.76e-12	90
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	35/1028	75/8135	3.69	3.97e-13	8.67e-12	75
GO:0002548	GO:0002548	monocyte chemotaxis	29/1028	54/8135	4.25	4.42e-13	9.60e-12	54
GO:0019882	GO:0019882	antigen processing and presentation	37/1028	83/8135	3.53	4.93e-13	1.06e-11	83
GO:0002687	GO:0002687	positive regulation of leukocyte migration	38/1028	87/8135	3.46	5.24e-13	1.12e-11	87
GO:0072676	GO:0072676	lymphocyte migration	36/1028	80/8135	3.56	7.20e-13	1.53e-11	80
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	47/1028	125/8135	2.98	7.71e-13	1.63e-11	125
GO:0050715	GO:0050715	positive regulation of cytokine secretion	38/1028	89/8135	3.38	1.25e-12	2.63e-11	89
GO:0006935	GO:0006935	chemotaxis	108/1028	441/8135	1.94	1.74e-12	3.63e-11	441
GO:0042330	GO:0042330	taxis	108/1028	442/8135	1.93	2.03e-12	4.22e-11	442
GO:0038094	GO:0038094	Fc-gamma receptor signaling pathway	20/1028	29/8135	5.46	2.96e-12	6.10e-11	29
GO:0050864	GO:0050864	regulation of B cell activation	33/1028	72/8135	3.63	3.52e-12	7.21e-11	72
GO:0032663	GO:0032663	regulation of interleukin-2 production	22/1028	35/8135	4.97	4.05e-12	8.24e-11	35
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	32/1028	69/8135	3.67	5.04e-12	1.02e-10	69
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	29/1028	59/8135	3.89	8.25e-12	1.66e-10	59
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	21/1028	33/8135	5.04	8.91e-12	1.78e-10	33
GO:0032653	GO:0032653	regulation of interleukin-10 production	22/1028	36/8135	4.84	9.17e-12	1.81e-10	36
GO:0045058	GO:0045058	T cell selection	22/1028	36/8135	4.84	9.17e-12	1.81e-10	36
GO:0032635	GO:0032635	interleukin-6 production	37/1028	91/8135	3.22	1.46e-11	2.86e-10	91
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	15/1028	18/8135	6.59	1.72e-11	3.34e-10	18
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	15/1028	18/8135	6.59	1.72e-11	3.34e-10	18
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	23/1028	40/8135	4.55	1.82e-11	3.49e-10	40
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	23/1028	40/8135	4.55	1.82e-11	3.49e-10	40
GO:0031295	GO:0031295	T cell costimulation	22/1028	37/8135	4.71	2.00e-11	3.78e-10	37
GO:0032613	GO:0032613	interleukin-10 production	22/1028	37/8135	4.71	2.00e-11	3.78e-10	37
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	34/1028	80/8135	3.36	2.26e-11	4.27e-10	80
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	14/1028	16/8135	6.92	2.29e-11	4.30e-10	16
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	48/1028	141/8135	2.69	2.88e-11	5.36e-10	141
GO:0048247	GO:0048247	lymphocyte chemotaxis	26/1028	51/8135	4.03	3.48e-11	6.45e-10	51
GO:0001906	GO:0001906	cell killing	40/1028	106/8135	2.99	3.53e-11	6.51e-10	106
GO:0031294	GO:0031294	lymphocyte costimulation	22/1028	38/8135	4.58	4.18e-11	7.66e-10	38
GO:0002431	GO:0002431	Fc receptor mediated stimulatory signaling pathway	19/1028	29/8135	5.18	4.21e-11	7.67e-10	29
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	31/1028	70/8135	3.50	4.82e-11	8.73e-10	70
GO:1990868	GO:1990868	response to chemokine	35/1028	86/8135	3.22	5.05e-11	9.06e-10	86
GO:1990869	GO:1990869	cellular response to chemokine	35/1028	86/8135	3.22	5.05e-11	9.06e-10	86
GO:0019724	GO:0019724	B cell mediated immunity	31/1028	71/8135	3.46	7.53e-11	1.34e-09	71
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	22/1028	39/8135	4.46	8.45e-11	1.50e-09	39
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	18/1028	27/8135	5.28	8.99e-11	1.59e-09	27
GO:0034612	GO:0034612	response to tumor necrosis factor	49/1028	150/8135	2.59	9.56e-11	1.66e-09	150
GO:0002886	GO:0002886	regulation of myeloid leukocyte mediated immunity	21/1028	36/8135	4.62	9.59e-11	1.66e-09	36
GO:0050853	GO:0050853	B cell receptor signaling pathway	21/1028	36/8135	4.62	9.59e-11	1.66e-09	36
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	11/1028	11/8135	7.91	1.25e-10	2.16e-09	11
GO:0051090	GO:0051090	regulation of DNA-binding transcription factor activity	58/1028	195/8135	2.35	1.26e-10	2.16e-09	195
GO:0044419	GO:0044419	interspecies interaction between organisms	73/1028	273/8135	2.12	1.27e-10	2.18e-09	273
GO:0072678	GO:0072678	T cell migration	23/1028	43/8135	4.23	1.35e-10	2.29e-09	43
GO:0032675	GO:0032675	regulation of interleukin-6 production	34/1028	85/8135	3.17	1.68e-10	2.84e-09	85
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	24/1028	47/8135	4.04	1.91e-10	3.21e-09	47
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	24/1028	47/8135	4.04	1.91e-10	3.21e-09	47
GO:0016064	GO:0016064	immunoglobulin mediated immune response	30/1028	70/8135	3.39	2.68e-10	4.46e-09	70
GO:0030099	GO:0030099	myeloid cell differentiation	61/1028	214/8135	2.26	2.83e-10	4.70e-09	214
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	26/1028	55/8135	3.74	3.02e-10	4.98e-09	55
GO:0072507	GO:0072507	divalent inorganic cation homeostasis	86/1028	350/8135	1.94	3.18e-10	5.22e-09	350
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	35/1028	91/8135	3.04	3.26e-10	5.33e-09	91
GO:0072503	GO:0072503	cellular divalent inorganic cation homeostasis	83/1028	334/8135	1.97	3.64e-10	5.92e-09	334
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	28/1028	63/8135	3.52	3.79e-10	6.13e-09	63
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	25/1028	52/8135	3.80	4.22e-10	6.80e-09	52
GO:0002433	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	17/1028	26/8135	5.17	4.83e-10	7.66e-09	26
GO:0038096	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	17/1028	26/8135	5.17	4.83e-10	7.66e-09	26
GO:0043368	GO:0043368	positive T cell selection	17/1028	26/8135	5.17	4.83e-10	7.66e-09	26
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	19/1028	32/8135	4.70	5.01e-10	7.91e-09	32
GO:0001776	GO:0001776	leukocyte homeostasis	27/1028	60/8135	3.56	5.54e-10	8.66e-09	60
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	27/1028	60/8135	3.56	5.54e-10	8.66e-09	60
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	64/1028	233/8135	2.17	5.57e-10	8.68e-09	233
GO:0006968	GO:0006968	cellular defense response	24/1028	49/8135	3.88	5.83e-10	9.03e-09	49
GO:0009615	GO:0009615	response to virus	50/1028	162/8135	2.44	5.91e-10	9.12e-09	162
GO:0031341	GO:0031341	regulation of cell killing	29/1028	68/8135	3.37	6.14e-10	9.42e-09	68
GO:0042116	GO:0042116	macrophage activation	25/1028	53/8135	3.73	7.05e-10	1.08e-08	53
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	37/1028	102/8135	2.87	7.19e-10	1.09e-08	102
GO:0044403	GO:0044403	symbiont process	66/1028	245/8135	2.13	7.28e-10	1.10e-08	245
GO:0070227	GO:0070227	lymphocyte apoptotic process	23/1028	46/8135	3.96	7.92e-10	1.19e-08	46
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	27/1028	61/8135	3.50	8.76e-10	1.31e-08	61
GO:0002448	GO:0002448	mast cell mediated immunity	20/1028	36/8135	4.40	8.96e-10	1.34e-08	36
GO:0055074	GO:0055074	calcium ion homeostasis	80/1028	323/8135	1.96	9.15e-10	1.36e-08	323
GO:0002224	GO:0002224	toll-like receptor signaling pathway	29/1028	69/8135	3.33	9.33e-10	1.38e-08	69
GO:0006874	GO:0006874	cellular calcium ion homeostasis	78/1028	312/8135	1.98	9.43e-10	1.39e-08	312
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	16/1028	24/8135	5.28	1.04e-09	1.52e-08	24
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	22/1028	43/8135	4.05	1.05e-09	1.54e-08	43
GO:0042088	GO:0042088	T-helper 1 type immune response	18/1028	30/8135	4.75	1.14e-09	1.65e-08	30
GO:0043300	GO:0043300	regulation of leukocyte degranulation	18/1028	30/8135	4.75	1.14e-09	1.65e-08	30
GO:0016032	GO:0016032	viral process	59/1028	211/8135	2.21	1.27e-09	1.83e-08	211
GO:0030316	GO:0030316	osteoclast differentiation	27/1028	62/8135	3.45	1.37e-09	1.96e-08	62
GO:0042093	GO:0042093	T-helper cell differentiation	20/1028	37/8135	4.28	1.72e-09	2.46e-08	37
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	22/1028	44/8135	3.96	1.86e-09	2.64e-08	44
GO:0007162	GO:0007162	negative regulation of cell adhesion	49/1028	162/8135	2.39	1.89e-09	2.68e-08	162
GO:0006875	GO:0006875	cellular metal ion homeostasis	88/1028	374/8135	1.86	2.05e-09	2.89e-08	374
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	19/1028	34/8135	4.42	2.08e-09	2.91e-08	34
GO:0043303	GO:0043303	mast cell degranulation	19/1028	34/8135	4.42	2.08e-09	2.91e-08	34
GO:0002440	GO:0002440	production of molecular mediator of immune response	39/1028	115/8135	2.68	2.39e-09	3.33e-08	115
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	18/1028	31/8135	4.59	2.40e-09	3.33e-08	31
GO:0070228	GO:0070228	regulation of lymphocyte apoptotic process	21/1028	41/8135	4.05	2.47e-09	3.41e-08	41
GO:0032633	GO:0032633	interleukin-4 production	17/1028	28/8135	4.80	2.58e-09	3.55e-08	28
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	13/1028	17/8135	6.05	2.85e-09	3.90e-08	17
GO:2000401	GO:2000401	regulation of lymphocyte migration	20/1028	38/8135	4.16	3.20e-09	4.33e-08	38
GO:0032637	GO:0032637	interleukin-8 production	22/1028	45/8135	3.87	3.21e-09	4.33e-08	45
GO:0045576	GO:0045576	mast cell activation	22/1028	45/8135	3.87	3.21e-09	4.33e-08	45
GO:0002279	GO:0002279	mast cell activation involved in immune response	19/1028	35/8135	4.30	4.02e-09	5.39e-08	35
GO:0032655	GO:0032655	regulation of interleukin-12 production	19/1028	35/8135	4.30	4.02e-09	5.39e-08	35
GO:0050920	GO:0050920	regulation of chemotaxis	45/1028	146/8135	2.44	4.54e-09	6.07e-08	146
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	40/1028	122/8135	2.59	4.57e-09	6.08e-08	122
GO:0042100	GO:0042100	B cell proliferation	26/1028	61/8135	3.37	4.84e-09	6.41e-08	61
GO:0009306	GO:0009306	protein secretion	81/1028	340/8135	1.89	5.07e-09	6.70e-08	340
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	15/1028	23/8135	5.16	5.55e-09	7.27e-08	23
GO:0046633	GO:0046633	alpha-beta T cell proliferation	15/1028	23/8135	5.16	5.55e-09	7.27e-08	23
GO:0048872	GO:0048872	homeostasis of number of cells	41/1028	128/8135	2.53	6.36e-09	8.29e-08	128
GO:0030003	GO:0030003	cellular cation homeostasis	92/1028	406/8135	1.79	6.59e-09	8.56e-08	406
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	24/1028	54/8135	3.52	6.89e-09	8.92e-08	54
GO:0002456	GO:0002456	T cell mediated immunity	28/1028	70/8135	3.17	6.94e-09	8.95e-08	70
GO:0032418	GO:0032418	lysosome localization	19/1028	36/8135	4.18	7.51e-09	9.58e-08	36
GO:0032615	GO:0032615	interleukin-12 production	19/1028	36/8135	4.18	7.51e-09	9.58e-08	36
GO:0002228	GO:0002228	natural killer cell mediated immunity	21/1028	43/8135	3.86	7.52e-09	9.58e-08	43
GO:0070374	GO:0070374	positive regulation of ERK1 and ERK2 cascade	50/1028	174/8135	2.27	8.83e-09	1.12e-07	174
GO:0050764	GO:0050764	regulation of phagocytosis	23/1028	51/8135	3.57	1.01e-08	1.28e-07	51
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	20/1028	40/8135	3.96	1.02e-08	1.28e-07	40
GO:0032677	GO:0032677	regulation of interleukin-8 production	20/1028	40/8135	3.96	1.02e-08	1.28e-07	40
GO:0055065	GO:0055065	metal ion homeostasis	94/1028	422/8135	1.76	1.12e-08	1.39e-07	422
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	14/1028	21/8135	5.28	1.20e-08	1.49e-07	21
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	14/1028	21/8135	5.28	1.20e-08	1.49e-07	21
GO:0043410	GO:0043410	positive regulation of MAPK cascade	84/1028	364/8135	1.83	1.28e-08	1.59e-07	364
GO:0032673	GO:0032673	regulation of interleukin-4 production	15/1028	24/8135	4.95	1.31e-08	1.60e-07	24
GO:0050777	GO:0050777	negative regulation of immune response	32/1028	89/8135	2.85	1.31e-08	1.60e-07	89
GO:0070555	GO:0070555	response to interleukin-1	32/1028	89/8135	2.85	1.31e-08	1.60e-07	89
GO:0030334	GO:0030334	regulation of cell migration	105/1028	490/8135	1.70	1.34e-08	1.63e-07	490
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	23/1028	52/8135	3.50	1.59e-08	1.93e-07	52
GO:0019722	GO:0019722	calcium-mediated signaling	44/1028	147/8135	2.37	1.82e-08	2.20e-07	147
GO:0043900	GO:0043900	regulation of multi-organism process	52/1028	188/8135	2.19	1.85e-08	2.23e-07	188
GO:0002790	GO:0002790	peptide secretion	84/1028	367/8135	1.81	1.92e-08	2.31e-07	367
GO:0050871	GO:0050871	positive regulation of B cell activation	21/1028	45/8135	3.69	2.10e-08	2.51e-07	45
GO:0030335	GO:0030335	positive regulation of cell migration	70/1028	287/8135	1.93	2.12e-08	2.53e-07	287
GO:0002698	GO:0002698	negative regulation of immune effector process	27/1028	69/8135	3.10	2.26e-08	2.68e-07	69
GO:0030168	GO:0030168	platelet activation	34/1028	100/8135	2.69	2.36e-08	2.80e-07	100
GO:0032612	GO:0032612	interleukin-1 production	26/1028	65/8135	3.17	2.40e-08	2.82e-07	65
GO:0150076	GO:0150076	neuroinflammatory response	19/1028	38/8135	3.96	2.41e-08	2.82e-07	38
GO:0002755	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/1028	19/8135	5.41	2.54e-08	2.96e-07	19
GO:2000406	GO:2000406	positive regulation of T cell migration	13/1028	19/8135	5.41	2.54e-08	2.96e-07	19
GO:0006873	GO:0006873	cellular ion homeostasis	92/1028	417/8135	1.75	2.65e-08	3.07e-07	417
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	15/1028	25/8135	4.75	2.89e-08	3.35e-07	25
GO:0032660	GO:0032660	regulation of interleukin-17 production	14/1028	22/8135	5.04	2.91e-08	3.35e-07	22
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	14/1028	22/8135	5.04	2.91e-08	3.35e-07	22
GO:0050921	GO:0050921	positive regulation of chemotaxis	32/1028	92/8135	2.75	3.29e-08	3.77e-07	92
GO:0030888	GO:0030888	regulation of B cell proliferation	21/1028	46/8135	3.61	3.40e-08	3.89e-07	46
GO:0040017	GO:0040017	positive regulation of locomotion	75/1028	319/8135	1.86	3.51e-08	4.00e-07	319
GO:0055080	GO:0055080	cation homeostasis	98/1028	457/8135	1.70	4.10e-08	4.65e-07	457
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	19/1028	39/8135	3.86	4.14e-08	4.68e-07	39
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	28/1028	75/8135	2.95	4.15e-08	4.68e-07	75
GO:0042742	GO:0042742	defense response to bacterium	45/1028	156/8135	2.28	4.34e-08	4.87e-07	156
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	65/1028	264/8135	1.95	4.69e-08	5.25e-07	264
GO:0050710	GO:0050710	negative regulation of cytokine secretion	20/1028	43/8135	3.68	4.90e-08	5.46e-07	43
GO:0030183	GO:0030183	B cell differentiation	26/1028	67/8135	3.07	5.04e-08	5.60e-07	67
GO:0031348	GO:0031348	negative regulation of defense response	37/1028	117/8135	2.50	5.10e-08	5.63e-07	117
GO:0002712	GO:0002712	regulation of B cell mediated immunity	16/1028	29/8135	4.37	5.13e-08	5.63e-07	29
GO:0002889	GO:0002889	regulation of immunoglobulin mediated immune response	16/1028	29/8135	4.37	5.13e-08	5.63e-07	29
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	16/1028	29/8135	4.37	5.13e-08	5.63e-07	29
GO:0002709	GO:0002709	regulation of T cell mediated immunity	21/1028	47/8135	3.54	5.43e-08	5.93e-07	47
GO:0098771	GO:0098771	inorganic ion homeostasis	99/1028	467/8135	1.68	6.36e-08	6.93e-07	467
GO:0051607	GO:0051607	defense response to virus	37/1028	118/8135	2.48	6.55e-08	7.10e-07	118
GO:0032620	GO:0032620	interleukin-17 production	14/1028	23/8135	4.82	6.58e-08	7.10e-07	23
GO:0045730	GO:0045730	respiratory burst	14/1028	23/8135	4.82	6.58e-08	7.10e-07	23
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	19/1028	40/8135	3.76	6.96e-08	7.48e-07	40
GO:0035747	GO:0035747	natural killer cell chemotaxis	9/1028	10/8135	7.12	7.07e-08	7.57e-07	10
GO:0002260	GO:0002260	lymphocyte homeostasis	20/1028	44/8135	3.60	7.93e-08	8.46e-07	44
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	28/1028	77/8135	2.88	8.03e-08	8.52e-07	77
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	28/1028	77/8135	2.88	8.03e-08	8.52e-07	77
GO:2000147	GO:2000147	positive regulation of cell motility	71/1028	302/8135	1.86	8.27e-08	8.74e-07	302
GO:0070371	GO:0070371	ERK1 and ERK2 cascade	58/1028	229/8135	2.00	8.84e-08	9.32e-07	229
GO:0010942	GO:0010942	positive regulation of cell death	74/1028	320/8135	1.83	8.99e-08	9.45e-07	320
GO:0043547	GO:0043547	positive regulation of GTPase activity	49/1028	181/8135	2.14	1.00e-07	1.05e-06	181
GO:0070372	GO:0070372	regulation of ERK1 and ERK2 cascade	56/1028	219/8135	2.02	1.04e-07	1.09e-06	219
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	28/1028	78/8135	2.84	1.10e-07	1.15e-06	78
GO:0002367	GO:0002367	cytokine production involved in immune response	25/1028	65/8135	3.04	1.12e-07	1.15e-06	65
GO:0007229	GO:0007229	integrin-mediated signaling pathway	25/1028	65/8135	3.04	1.12e-07	1.15e-06	65
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	25/1028	65/8135	3.04	1.12e-07	1.15e-06	65
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	35/1028	111/8135	2.50	1.27e-07	1.31e-06	111
GO:0031343	GO:0031343	positive regulation of cell killing	21/1028	49/8135	3.39	1.31e-07	1.35e-06	49
GO:1901623	GO:1901623	regulation of lymphocyte chemotaxis	12/1028	18/8135	5.28	1.40e-07	1.42e-06	18
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	14/1028	24/8135	4.62	1.40e-07	1.42e-06	24
GO:0001773	GO:0001773	myeloid dendritic cell activation	13/1028	21/8135	4.90	1.49e-07	1.51e-06	21
GO:0045066	GO:0045066	regulatory T cell differentiation	13/1028	21/8135	4.90	1.49e-07	1.51e-06	21
GO:0051208	GO:0051208	sequestering of calcium ion	28/1028	79/8135	2.80	1.51e-07	1.52e-06	79
GO:0043087	GO:0043087	regulation of GTPase activity	55/1028	216/8135	2.01	1.58e-07	1.59e-06	216
GO:0045453	GO:0045453	bone resorption	19/1028	42/8135	3.58	1.84e-07	1.85e-06	42
GO:0032611	GO:0032611	interleukin-1 beta production	22/1028	54/8135	3.22	1.96e-07	1.96e-06	54
GO:0002831	GO:0002831	regulation of response to biotic stimulus	25/1028	67/8135	2.95	2.23e-07	2.23e-06	67
GO:0032479	GO:0032479	regulation of type I interferon production	18/1028	39/8135	3.65	2.67e-07	2.64e-06	39
GO:0032606	GO:0032606	type I interferon production	18/1028	39/8135	3.65	2.67e-07	2.64e-06	39
GO:0050766	GO:0050766	positive regulation of phagocytosis	18/1028	39/8135	3.65	2.67e-07	2.64e-06	39
GO:0051272	GO:0051272	positive regulation of cellular component movement	71/1028	311/8135	1.81	2.82e-07	2.77e-06	311
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	19/1028	43/8135	3.50	2.92e-07	2.86e-06	43
GO:0002377	GO:0002377	immunoglobulin production	21/1028	51/8135	3.26	3.00e-07	2.94e-06	51
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	16/1028	32/8135	3.96	3.13e-07	3.04e-06	32
GO:0070231	GO:0070231	T cell apoptotic process	16/1028	32/8135	3.96	3.13e-07	3.04e-06	32
GO:0071675	GO:0071675	regulation of mononuclear cell migration	16/1028	32/8135	3.96	3.13e-07	3.04e-06	32
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	30/1028	91/8135	2.61	3.41e-07	3.30e-06	91
GO:0032695	GO:0032695	negative regulation of interleukin-12 production	9/1028	11/8135	6.47	3.45e-07	3.33e-06	11
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	17/1028	36/8135	3.74	3.82e-07	3.68e-06	36
GO:0051222	GO:0051222	positive regulation of protein transport	54/1028	216/8135	1.98	3.89e-07	3.73e-06	216
GO:0030100	GO:0030100	regulation of endocytosis	38/1028	131/8135	2.30	4.17e-07	3.99e-06	131
GO:0006911	GO:0006911	phagocytosis, engulfment	15/1028	29/8135	4.09	4.18e-07	3.99e-06	29
GO:0032755	GO:0032755	positive regulation of interleukin-6 production	22/1028	56/8135	3.11	4.19e-07	3.99e-06	56
GO:0002312	GO:0002312	B cell activation involved in immune response	18/1028	40/8135	3.56	4.29e-07	4.07e-06	40
GO:0045670	GO:0045670	regulation of osteoclast differentiation	19/1028	44/8135	3.42	4.53e-07	4.28e-06	44
GO:0051235	GO:0051235	maintenance of location	45/1028	168/8135	2.12	4.64e-07	4.37e-06	168
GO:1904951	GO:1904951	positive regulation of establishment of protein localization	55/1028	223/8135	1.95	4.87e-07	4.58e-06	223
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	28/1028	83/8135	2.67	4.90e-07	4.60e-06	83
GO:0001774	GO:0001774	microglial cell activation	14/1028	26/8135	4.26	5.37e-07	5.01e-06	26
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	14/1028	26/8135	4.26	5.37e-07	5.01e-06	26
GO:0043068	GO:0043068	positive regulation of programmed cell death	66/1028	287/8135	1.82	5.66e-07	5.26e-06	287
GO:0050714	GO:0050714	positive regulation of protein secretion	44/1028	164/8135	2.12	5.92e-07	5.49e-06	164
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	22/1028	57/8135	3.05	6.02e-07	5.57e-06	57
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	21/1028	53/8135	3.14	6.49e-07	5.98e-06	53
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	13/1028	23/8135	4.47	6.56e-07	5.99e-06	23
GO:0032481	GO:0032481	positive regulation of type I interferon production	13/1028	23/8135	4.47	6.56e-07	5.99e-06	23
GO:1905521	GO:1905521	regulation of macrophage migration	13/1028	23/8135	4.47	6.56e-07	5.99e-06	23
GO:1903530	GO:1903530	regulation of secretion by cell	95/1028	465/8135	1.62	7.23e-07	6.58e-06	465
GO:0050708	GO:0050708	regulation of protein secretion	65/1028	283/8135	1.82	7.23e-07	6.58e-06	283
GO:0033003	GO:0033003	regulation of mast cell activation	15/1028	30/8135	3.96	7.39e-07	6.66e-06	30
GO:0002714	GO:0002714	positive regulation of B cell mediated immunity	12/1028	20/8135	4.75	7.42e-07	6.66e-06	20
GO:0002891	GO:0002891	positive regulation of immunoglobulin mediated immune response	12/1028	20/8135	4.75	7.42e-07	6.66e-06	20
GO:0050869	GO:0050869	negative regulation of B cell activation	12/1028	20/8135	4.75	7.42e-07	6.66e-06	20
GO:0002544	GO:0002544	chronic inflammatory response	11/1028	17/8135	5.12	7.47e-07	6.66e-06	17
GO:0042533	GO:0042533	tumor necrosis factor biosynthetic process	11/1028	17/8135	5.12	7.47e-07	6.66e-06	17
GO:0042534	GO:0042534	regulation of tumor necrosis factor biosynthetic process	11/1028	17/8135	5.12	7.47e-07	6.66e-06	17
GO:1905517	GO:1905517	macrophage migration	16/1028	34/8135	3.72	8.97e-07	7.98e-06	34
GO:0071347	GO:0071347	cellular response to interleukin-1	26/1028	76/8135	2.71	9.21e-07	8.17e-06	76
GO:0043065	GO:0043065	positive regulation of apoptotic process	65/1028	285/8135	1.80	9.43e-07	8.34e-06	285
GO:2000404	GO:2000404	regulation of T cell migration	14/1028	27/8135	4.10	9.87e-07	8.71e-06	27
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	17/1028	38/8135	3.54	9.98e-07	8.78e-06	38
GO:0045807	GO:0045807	positive regulation of endocytosis	27/1028	81/8135	2.64	1.03e-06	9.00e-06	81
GO:0002791	GO:0002791	regulation of peptide secretion	68/1028	305/8135	1.76	1.26e-06	1.10e-05	305
GO:0010324	GO:0010324	membrane invagination	15/1028	31/8135	3.83	1.27e-06	1.10e-05	31
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	15/1028	31/8135	3.83	1.27e-06	1.10e-05	31
GO:0099024	GO:0099024	plasma membrane invagination	15/1028	31/8135	3.83	1.27e-06	1.10e-05	31
GO:0033674	GO:0033674	positive regulation of kinase activity	68/1028	306/8135	1.76	1.43e-06	1.24e-05	306
GO:0042130	GO:0042130	negative regulation of T cell proliferation	16/1028	35/8135	3.62	1.46e-06	1.26e-05	35
GO:0050702	GO:0050702	interleukin-1 beta secretion	16/1028	35/8135	3.62	1.46e-06	1.26e-05	35
GO:0043304	GO:0043304	regulation of mast cell degranulation	12/1028	21/8135	4.52	1.53e-06	1.32e-05	21
GO:0045123	GO:0045123	cellular extravasation	18/1028	43/8135	3.31	1.59e-06	1.36e-05	43
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	10/1028	15/8135	5.28	1.64e-06	1.40e-05	15
GO:0009595	GO:0009595	detection of biotic stimulus	11/1028	18/8135	4.84	1.70e-06	1.45e-05	18
GO:0070232	GO:0070232	regulation of T cell apoptotic process	14/1028	28/8135	3.96	1.74e-06	1.48e-05	28
GO:0019932	GO:0019932	second-messenger-mediated signaling	69/1028	314/8135	1.74	1.83e-06	1.56e-05	314
GO:0045862	GO:0045862	positive regulation of proteolysis	39/1028	144/8135	2.14	2.00e-06	1.69e-05	144
GO:0060402	GO:0060402	calcium ion transport into cytosol	31/1028	103/8135	2.38	2.04e-06	1.72e-05	103
GO:0061900	GO:0061900	glial cell activation	15/1028	32/8135	3.71	2.11e-06	1.77e-05	32
GO:0001911	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	8/1028	10/8135	6.33	2.26e-06	1.88e-05	10
GO:0002430	GO:0002430	complement receptor mediated signaling pathway	8/1028	10/8135	6.33	2.26e-06	1.88e-05	10
GO:0030889	GO:0030889	negative regulation of B cell proliferation	8/1028	10/8135	6.33	2.26e-06	1.88e-05	10
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	22/1028	61/8135	2.85	2.31e-06	1.93e-05	61
GO:0001913	GO:0001913	T cell mediated cytotoxicity	16/1028	36/8135	3.52	2.32e-06	1.93e-05	36
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	13/1028	25/8135	4.11	2.33e-06	1.93e-05	25
GO:0072677	GO:0072677	eosinophil migration	13/1028	25/8135	4.11	2.33e-06	1.93e-05	25
GO:0060401	GO:0060401	cytosolic calcium ion transport	31/1028	104/8135	2.36	2.56e-06	2.11e-05	104
GO:0032652	GO:0032652	regulation of interleukin-1 production	21/1028	57/8135	2.92	2.64e-06	2.17e-05	57
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	14/1028	29/8135	3.82	2.98e-06	2.43e-05	29
GO:0097028	GO:0097028	dendritic cell differentiation	14/1028	29/8135	3.82	2.98e-06	2.43e-05	29
GO:0033006	GO:0033006	regulation of mast cell activation involved in immune response	12/1028	22/8135	4.32	2.98e-06	2.43e-05	22
GO:0072606	GO:0072606	interleukin-8 secretion	12/1028	22/8135	4.32	2.98e-06	2.43e-05	22
GO:0002793	GO:0002793	positive regulation of peptide secretion	45/1028	179/8135	1.99	3.09e-06	2.51e-05	179
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	9/1028	13/8135	5.48	3.53e-06	2.86e-05	13
GO:0002507	GO:0002507	tolerance induction	11/1028	19/8135	4.58	3.58e-06	2.87e-05	19
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	11/1028	19/8135	4.58	3.58e-06	2.87e-05	19
GO:0150077	GO:0150077	regulation of neuroinflammatory response	11/1028	19/8135	4.58	3.58e-06	2.87e-05	19
GO:2000482	GO:2000482	regulation of interleukin-8 secretion	11/1028	19/8135	4.58	3.58e-06	2.87e-05	19
GO:0002220	GO:0002220	innate immune response activating cell surface receptor signaling pathway	16/1028	37/8135	3.42	3.61e-06	2.88e-05	37
GO:0002532	GO:0002532	production of molecular mediator involved in inflammatory response	16/1028	37/8135	3.42	3.61e-06	2.88e-05	37
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	26/1028	81/8135	2.54	3.62e-06	2.88e-05	81
GO:0050701	GO:0050701	interleukin-1 secretion	17/1028	41/8135	3.28	3.62e-06	2.88e-05	41
GO:0051047	GO:0051047	positive regulation of secretion	61/1028	272/8135	1.77	3.67e-06	2.91e-05	272
GO:1903532	GO:1903532	positive regulation of secretion by cell	57/1028	250/8135	1.80	4.48e-06	3.55e-05	250
GO:0051223	GO:0051223	regulation of protein transport	74/1028	353/8135	1.66	4.92e-06	3.88e-05	353
GO:0032715	GO:0032715	negative regulation of interleukin-6 production	14/1028	30/8135	3.69	4.95e-06	3.90e-05	30
GO:0043281	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	29/1028	97/8135	2.37	5.02e-06	3.95e-05	97
GO:0060627	GO:0060627	regulation of vesicle-mediated transport	58/1028	257/8135	1.79	5.19e-06	4.07e-05	257
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	15/1028	34/8135	3.49	5.40e-06	4.22e-05	34
GO:0043408	GO:0043408	regulation of MAPK cascade	92/1028	467/8135	1.56	5.51e-06	4.30e-05	467
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	12/1028	23/8135	4.13	5.52e-06	4.30e-05	23
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	20/1028	55/8135	2.88	5.75e-06	4.47e-05	55
GO:2000116	GO:2000116	regulation of cysteine-type endopeptidase activity	32/1028	113/8135	2.24	5.96e-06	4.61e-05	113
GO:0055082	GO:0055082	cellular chemical homeostasis	95/1028	488/8135	1.54	6.49e-06	5.02e-05	488
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	19/1028	51/8135	2.95	6.51e-06	5.02e-05	51
GO:0070201	GO:0070201	regulation of establishment of protein localization	75/1028	362/8135	1.64	6.64e-06	5.11e-05	362
GO:0002526	GO:0002526	acute inflammatory response	33/1028	119/8135	2.19	7.02e-06	5.37e-05	119
GO:0002381	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	13/1028	27/8135	3.81	7.04e-06	5.37e-05	27
GO:0010818	GO:0010818	T cell chemotaxis	11/1028	20/8135	4.35	7.05e-06	5.37e-05	20
GO:0036336	GO:0036336	dendritic cell migration	11/1028	20/8135	4.35	7.05e-06	5.37e-05	20
GO:0031342	GO:0031342	negative regulation of cell killing	8/1028	11/8135	5.76	7.35e-06	5.56e-05	11
GO:0036005	GO:0036005	response to macrophage colony-stimulating factor	8/1028	11/8135	5.76	7.35e-06	5.56e-05	11
GO:0036006	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	8/1028	11/8135	5.76	7.35e-06	5.56e-05	11
GO:0090087	GO:0090087	regulation of peptide transport	77/1028	376/8135	1.62	7.82e-06	5.90e-05	376
GO:0043030	GO:0043030	regulation of macrophage activation	15/1028	35/8135	3.39	8.35e-06	6.27e-05	35
GO:0048010	GO:0048010	vascular endothelial growth factor receptor signaling pathway	15/1028	35/8135	3.39	8.35e-06	6.27e-05	35
GO:2000108	GO:2000108	positive regulation of leukocyte apoptotic process	10/1028	17/8135	4.65	8.36e-06	6.27e-05	17
GO:0043373	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	9/1028	14/8135	5.09	8.78e-06	6.57e-05	14
GO:0046849	GO:0046849	bone remodeling	21/1028	61/8135	2.72	9.14e-06	6.82e-05	61
GO:0010950	GO:0010950	positive regulation of endopeptidase activity	25/1028	80/8135	2.47	9.47e-06	7.05e-05	80
GO:0034113	GO:0034113	heterotypic cell-cell adhesion	17/1028	44/8135	3.06	1.13e-05	8.40e-05	44
GO:0051347	GO:0051347	positive regulation of transferase activity	69/1028	330/8135	1.65	1.13e-05	8.40e-05	330
GO:0002820	GO:0002820	negative regulation of adaptive immune response	13/1028	28/8135	3.67	1.16e-05	8.61e-05	28
GO:0043062	GO:0043062	extracellular structure organization	64/1028	300/8135	1.69	1.21e-05	8.93e-05	300
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	16/1028	40/8135	3.17	1.22e-05	8.97e-05	40
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	14/1028	32/8135	3.46	1.25e-05	9.20e-05	32
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	14/1028	32/8135	3.46	1.25e-05	9.20e-05	32
GO:0072538	GO:0072538	T-helper 17 type immune response	11/1028	21/8135	4.15	1.31e-05	9.60e-05	21
GO:0043029	GO:0043029	T cell homeostasis	12/1028	25/8135	3.80	1.67e-05	1.21e-04	25
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	10/1028	18/8135	4.40	1.67e-05	1.21e-04	18
GO:0045577	GO:0045577	regulation of B cell differentiation	10/1028	18/8135	4.40	1.67e-05	1.21e-04	18
GO:0045860	GO:0045860	positive regulation of protein kinase activity	61/1028	285/8135	1.69	1.74e-05	1.26e-04	285
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	16/1028	41/8135	3.09	1.77e-05	1.28e-04	41
GO:0045637	GO:0045637	regulation of myeloid cell differentiation	35/1028	135/8135	2.05	1.88e-05	1.36e-04	135
GO:0008360	GO:0008360	regulation of cell shape	24/1028	78/8135	2.43	1.90e-05	1.37e-04	78
GO:0010952	GO:0010952	positive regulation of peptidase activity	26/1028	88/8135	2.34	1.94e-05	1.39e-04	88
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	9/1028	15/8135	4.75	1.95e-05	1.39e-04	15
GO:0032607	GO:0032607	interferon-alpha production	9/1028	15/8135	4.75	1.95e-05	1.39e-04	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	9/1028	15/8135	4.75	1.95e-05	1.39e-04	15
GO:0045061	GO:0045061	thymic T cell selection	9/1028	15/8135	4.75	1.95e-05	1.39e-04	15
GO:0098581	GO:0098581	detection of external biotic stimulus	9/1028	15/8135	4.75	1.95e-05	1.39e-04	15
GO:1905523	GO:1905523	positive regulation of macrophage migration	8/1028	12/8135	5.28	1.96e-05	1.39e-04	12
GO:0030101	GO:0030101	natural killer cell activation	18/1028	50/8135	2.85	1.97e-05	1.40e-04	50
GO:0032651	GO:0032651	regulation of interleukin-1 beta production	17/1028	46/8135	2.92	2.25e-05	1.59e-04	46
GO:0002828	GO:0002828	regulation of type 2 immune response	11/1028	22/8135	3.96	2.32e-05	1.64e-04	22
GO:0050718	GO:0050718	positive regulation of interleukin-1 beta secretion	11/1028	22/8135	3.96	2.32e-05	1.64e-04	22
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	24/1028	79/8135	2.40	2.41e-05	1.69e-04	79
GO:0006959	GO:0006959	humoral immune response	44/1028	187/8135	1.86	2.42e-05	1.70e-04	187
GO:0050848	GO:0050848	regulation of calcium-mediated signaling	20/1028	60/8135	2.64	2.56e-05	1.79e-04	60
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	12/1028	26/8135	3.65	2.74e-05	1.91e-04	26
GO:0042092	GO:0042092	type 2 immune response	12/1028	26/8135	3.65	2.74e-05	1.91e-04	26
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	28/1028	100/8135	2.22	2.83e-05	1.96e-04	100
GO:0002223	GO:0002223	stimulatory C-type lectin receptor signaling pathway	14/1028	34/8135	3.26	2.90e-05	2.01e-04	34
GO:0002686	GO:0002686	negative regulation of leukocyte migration	14/1028	34/8135	3.26	2.90e-05	2.01e-04	34
GO:0032880	GO:0032880	regulation of protein localization	89/1028	467/8135	1.51	3.02e-05	2.09e-04	467
GO:0022617	GO:0022617	extracellular matrix disassembly	19/1028	56/8135	2.68	3.07e-05	2.11e-04	56
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	10/1028	19/8135	4.16	3.12e-05	2.14e-04	19
GO:0072539	GO:0072539	T-helper 17 cell differentiation	10/1028	19/8135	4.16	3.12e-05	2.14e-04	19
GO:0090025	GO:0090025	regulation of monocyte chemotaxis	10/1028	19/8135	4.16	3.12e-05	2.14e-04	19
GO:0048771	GO:0048771	tissue remodeling	29/1028	106/8135	2.16	3.29e-05	2.25e-04	106
GO:1903707	GO:1903707	negative regulation of hemopoiesis	26/1028	91/8135	2.26	3.70e-05	2.52e-04	91
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	23/1028	76/8135	2.39	3.80e-05	2.59e-04	76
GO:1903531	GO:1903531	negative regulation of secretion by cell	32/1028	123/8135	2.06	3.94e-05	2.67e-04	123
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	9/1028	16/8135	4.45	3.96e-05	2.67e-04	16
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	9/1028	16/8135	4.45	3.96e-05	2.67e-04	16
GO:0071677	GO:0071677	positive regulation of mononuclear cell migration	9/1028	16/8135	4.45	3.96e-05	2.67e-04	16
GO:0031532	GO:0031532	actin cytoskeleton reorganization	17/1028	48/8135	2.80	4.27e-05	2.87e-04	48
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	7/1028	10/8135	5.54	4.28e-05	2.88e-04	10
GO:0045428	GO:0045428	regulation of nitric oxide biosynthetic process	13/1028	31/8135	3.32	4.45e-05	2.98e-04	31
GO:0002295	GO:0002295	T-helper cell lineage commitment	8/1028	13/8135	4.87	4.53e-05	3.01e-04	13
GO:0006925	GO:0006925	inflammatory cell apoptotic process	8/1028	13/8135	4.87	4.53e-05	3.01e-04	13
GO:0090026	GO:0090026	positive regulation of monocyte chemotaxis	8/1028	13/8135	4.87	4.53e-05	3.01e-04	13
GO:0150078	GO:0150078	positive regulation of neuroinflammatory response	8/1028	13/8135	4.87	4.53e-05	3.01e-04	13
GO:0051924	GO:0051924	regulation of calcium ion transport	39/1028	163/8135	1.89	4.68e-05	3.11e-04	163
GO:0002702	GO:0002702	positive regulation of production of molecular mediator of immune response	18/1028	53/8135	2.69	4.87e-05	3.22e-04	53
GO:1903725	GO:1903725	regulation of phospholipid metabolic process	16/1028	44/8135	2.88	4.93e-05	3.26e-04	44
GO:0019058	GO:0019058	viral life cycle	31/1028	119/8135	2.06	5.04e-05	3.32e-04	119
GO:0035590	GO:0035590	purinergic nucleotide receptor signaling pathway	10/1028	20/8135	3.96	5.54e-05	3.64e-04	20
GO:0043032	GO:0043032	positive regulation of macrophage activation	10/1028	20/8135	3.96	5.54e-05	3.64e-04	20
GO:0006919	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	15/1028	40/8135	2.97	5.59e-05	3.66e-04	40
GO:0046209	GO:0046209	nitric oxide metabolic process	15/1028	40/8135	2.97	5.59e-05	3.66e-04	40
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	15/1028	40/8135	2.97	5.59e-05	3.66e-04	40
GO:0002792	GO:0002792	negative regulation of peptide secretion	24/1028	83/8135	2.29	5.91e-05	3.85e-04	83
GO:0070838	GO:0070838	divalent metal ion transport	61/1028	297/8135	1.63	6.35e-05	4.14e-04	297
GO:0007596	GO:0007596	blood coagulation	46/1028	206/8135	1.77	6.42e-05	4.17e-04	206
GO:0010517	GO:0010517	regulation of phospholipase activity	18/1028	54/8135	2.64	6.45e-05	4.17e-04	54
GO:1905954	GO:1905954	positive regulation of lipid localization	18/1028	54/8135	2.64	6.45e-05	4.17e-04	54
GO:1902622	GO:1902622	regulation of neutrophil migration	11/1028	24/8135	3.63	6.46e-05	4.17e-04	24
GO:0030574	GO:0030574	collagen catabolic process	13/1028	32/8135	3.21	6.63e-05	4.27e-04	32
GO:0006898	GO:0006898	receptor-mediated endocytosis	41/1028	177/8135	1.83	6.67e-05	4.29e-04	177
GO:0014068	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	16/1028	45/8135	2.81	6.76e-05	4.33e-04	45
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	12/1028	28/8135	3.39	6.77e-05	4.33e-04	28
GO:0032731	GO:0032731	positive regulation of interleukin-1 beta production	12/1028	28/8135	3.39	6.77e-05	4.33e-04	28
GO:0046718	GO:0046718	viral entry into host cell	20/1028	64/8135	2.47	7.29e-05	4.65e-04	64
GO:0018108	GO:0018108	peptidyl-tyrosine phosphorylation	51/1028	237/8135	1.70	7.31e-05	4.65e-04	237
GO:0018212	GO:0018212	peptidyl-tyrosine modification	51/1028	237/8135	1.70	7.31e-05	4.65e-04	237
GO:2000249	GO:2000249	regulation of actin cytoskeleton reorganization	9/1028	17/8135	4.19	7.46e-05	4.73e-04	17
GO:2001056	GO:2001056	positive regulation of cysteine-type endopeptidase activity	21/1028	69/8135	2.41	7.47e-05	4.73e-04	69
GO:0006816	GO:0006816	calcium ion transport	57/1028	274/8135	1.65	7.62e-05	4.82e-04	274
GO:0072511	GO:0072511	divalent inorganic cation transport	61/1028	299/8135	1.61	7.78e-05	4.91e-04	299
GO:0070588	GO:0070588	calcium ion transmembrane transport	44/1028	196/8135	1.78	8.07e-05	5.08e-04	196
GO:0007599	GO:0007599	hemostasis	46/1028	208/8135	1.75	8.23e-05	5.17e-04	208
GO:0032602	GO:0032602	chemokine production	19/1028	60/8135	2.51	8.99e-05	5.64e-04	60
GO:0050817	GO:0050817	coagulation	46/1028	209/8135	1.74	9.29e-05	5.81e-04	209
GO:0051048	GO:0051048	negative regulation of secretion	35/1028	145/8135	1.91	9.35e-05	5.81e-04	145
GO:0048245	GO:0048245	eosinophil chemotaxis	10/1028	21/8135	3.77	9.39e-05	5.81e-04	21
GO:0035589	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	8/1028	14/8135	4.52	9.40e-05	5.81e-04	14
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	8/1028	14/8135	4.52	9.40e-05	5.81e-04	14
GO:0055094	GO:0055094	response to lipoprotein particle	8/1028	14/8135	4.52	9.40e-05	5.81e-04	14
GO:0097242	GO:0097242	amyloid-beta clearance	8/1028	14/8135	4.52	9.40e-05	5.81e-04	14
GO:0140131	GO:0140131	positive regulation of lymphocyte chemotaxis	8/1028	14/8135	4.52	9.40e-05	5.81e-04	14
GO:0002637	GO:0002637	regulation of immunoglobulin production	13/1028	33/8135	3.12	9.68e-05	5.95e-04	33
GO:0032732	GO:0032732	positive regulation of interleukin-1 production	13/1028	33/8135	3.12	9.68e-05	5.95e-04	33
GO:0050688	GO:0050688	regulation of defense response to virus	13/1028	33/8135	3.12	9.68e-05	5.95e-04	33
GO:0030198	GO:0030198	extracellular matrix organization	55/1028	264/8135	1.65	9.74e-05	5.97e-04	264
GO:0030225	GO:0030225	macrophage differentiation	11/1028	25/8135	3.48	1.02e-04	6.23e-04	25
GO:0045581	GO:0045581	negative regulation of T cell differentiation	11/1028	25/8135	3.48	1.02e-04	6.23e-04	25
GO:0050706	GO:0050706	regulation of interleukin-1 beta secretion	12/1028	29/8135	3.27	1.02e-04	6.23e-04	29
GO:1903727	GO:1903727	positive regulation of phospholipid metabolic process	12/1028	29/8135	3.27	1.02e-04	6.23e-04	29
GO:0002756	GO:0002756	MyD88-independent toll-like receptor signaling pathway	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0043371	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0043383	GO:0043383	negative T cell selection	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0045408	GO:0045408	regulation of interleukin-6 biosynthetic process	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0046629	GO:0046629	gamma-delta T cell activation	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0070230	GO:0070230	positive regulation of lymphocyte apoptotic process	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0072540	GO:0072540	T-helper 17 cell lineage commitment	7/1028	11/8135	5.04	1.05e-04	6.30e-04	11
GO:0043901	GO:0043901	negative regulation of multi-organism process	25/1028	91/8135	2.17	1.05e-04	6.31e-04	91
GO:0051051	GO:0051051	negative regulation of transport	56/1028	271/8135	1.64	1.06e-04	6.36e-04	271
GO:0006801	GO:0006801	superoxide metabolic process	15/1028	42/8135	2.83	1.07e-04	6.40e-04	42
GO:0033077	GO:0033077	T cell differentiation in thymus	15/1028	42/8135	2.83	1.07e-04	6.40e-04	42
GO:2001057	GO:2001057	reactive nitrogen species metabolic process	15/1028	42/8135	2.83	1.07e-04	6.40e-04	42
GO:1903409	GO:1903409	reactive oxygen species biosynthetic process	18/1028	56/8135	2.54	1.10e-04	6.56e-04	56
GO:0050709	GO:0050709	negative regulation of protein secretion	22/1028	76/8135	2.29	1.17e-04	6.92e-04	76
GO:0006809	GO:0006809	nitric oxide biosynthetic process	14/1028	38/8135	2.92	1.24e-04	7.32e-04	38
GO:0030162	GO:0030162	regulation of proteolysis	72/1028	374/8135	1.52	1.27e-04	7.53e-04	374
GO:0002360	GO:0002360	T cell lineage commitment	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0002407	GO:0002407	dendritic cell chemotaxis	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0002888	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0030866	GO:0030866	cortical actin cytoskeleton organization	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0045671	GO:0045671	negative regulation of osteoclast differentiation	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0070233	GO:0070233	negative regulation of T cell apoptotic process	9/1028	18/8135	3.96	1.33e-04	7.75e-04	18
GO:0050728	GO:0050728	negative regulation of inflammatory response	24/1028	87/8135	2.18	1.34e-04	7.79e-04	87
GO:1905952	GO:1905952	regulation of lipid localization	24/1028	87/8135	2.18	1.34e-04	7.79e-04	87
GO:0043280	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	18/1028	57/8135	2.50	1.43e-04	8.28e-04	57
GO:0030260	GO:0030260	entry into host cell	20/1028	67/8135	2.36	1.48e-04	8.56e-04	67
GO:0044409	GO:0044409	entry into host	20/1028	67/8135	2.36	1.48e-04	8.56e-04	67
GO:0051806	GO:0051806	entry into cell of other organism involved in symbiotic interaction	20/1028	67/8135	2.36	1.48e-04	8.56e-04	67
GO:0051828	GO:0051828	entry into other organism involved in symbiotic interaction	20/1028	67/8135	2.36	1.48e-04	8.56e-04	67
GO:0032102	GO:0032102	negative regulation of response to external stimulus	45/1028	207/8135	1.72	1.50e-04	8.62e-04	207
GO:0002720	GO:0002720	positive regulation of cytokine production involved in immune response	12/1028	30/8135	3.17	1.51e-04	8.66e-04	30
GO:0009620	GO:0009620	response to fungus	12/1028	30/8135	3.17	1.51e-04	8.66e-04	30
GO:0034142	GO:0034142	toll-like receptor 4 signaling pathway	10/1028	22/8135	3.60	1.53e-04	8.70e-04	22
GO:0050901	GO:0050901	leukocyte tethering or rolling	10/1028	22/8135	3.60	1.53e-04	8.70e-04	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	10/1028	22/8135	3.60	1.53e-04	8.70e-04	22
GO:0010543	GO:0010543	regulation of platelet activation	11/1028	26/8135	3.35	1.57e-04	8.93e-04	26
GO:0050716	GO:0050716	positive regulation of interleukin-1 secretion	11/1028	26/8135	3.35	1.57e-04	8.93e-04	26
GO:0072593	GO:0072593	reactive oxygen species metabolic process	34/1028	143/8135	1.88	1.60e-04	9.10e-04	143
GO:0002577	GO:0002577	regulation of antigen processing and presentation	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:0002689	GO:0002689	negative regulation of leukocyte chemotaxis	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:0032604	GO:0032604	granulocyte macrophage colony-stimulating factor production	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:0042832	GO:0042832	defense response to protozoan	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:0071402	GO:0071402	cellular response to lipoprotein particle stimulus	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:2000316	GO:2000316	regulation of T-helper 17 type immune response	8/1028	15/8135	4.22	1.79e-04	1.01e-03	15
GO:0010863	GO:0010863	positive regulation of phospholipase C activity	13/1028	35/8135	2.94	1.96e-04	1.09e-03	35
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	13/1028	35/8135	2.94	1.96e-04	1.09e-03	35
GO:0051928	GO:0051928	positive regulation of calcium ion transport	22/1028	79/8135	2.20	2.17e-04	1.21e-03	79
GO:0045124	GO:0045124	regulation of bone resorption	12/1028	31/8135	3.06	2.19e-04	1.22e-03	31
GO:0002719	GO:0002719	negative regulation of cytokine production involved in immune response	9/1028	19/8135	3.75	2.24e-04	1.24e-03	19
GO:0033032	GO:0033032	regulation of myeloid cell apoptotic process	9/1028	19/8135	3.75	2.24e-04	1.24e-03	19
GO:0050856	GO:0050856	regulation of T cell receptor signaling pathway	9/1028	19/8135	3.75	2.24e-04	1.24e-03	19
GO:0042226	GO:0042226	interleukin-6 biosynthetic process	7/1028	12/8135	4.62	2.24e-04	1.24e-03	12
GO:0098543	GO:0098543	detection of other organism	7/1028	12/8135	4.62	2.24e-04	1.24e-03	12
GO:1903978	GO:1903978	regulation of microglial cell activation	7/1028	12/8135	4.62	2.24e-04	1.24e-03	12
GO:0002673	GO:0002673	regulation of acute inflammatory response	21/1028	74/8135	2.25	2.25e-04	1.24e-03	74
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	20/1028	69/8135	2.29	2.31e-04	1.27e-03	69
GO:0060191	GO:0060191	regulation of lipase activity	20/1028	69/8135	2.29	2.31e-04	1.27e-03	69
GO:0045824	GO:0045824	negative regulation of innate immune response	11/1028	27/8135	3.22	2.35e-04	1.29e-03	27
GO:0050850	GO:0050850	positive regulation of calcium-mediated signaling	11/1028	27/8135	3.22	2.35e-04	1.29e-03	27
GO:1903053	GO:1903053	regulation of extracellular matrix organization	10/1028	23/8135	3.44	2.40e-04	1.31e-03	23
GO:0010518	GO:0010518	positive regulation of phospholipase activity	15/1028	45/8135	2.64	2.60e-04	1.42e-03	45
GO:0002763	GO:0002763	positive regulation of myeloid leukocyte differentiation	13/1028	36/8135	2.86	2.71e-04	1.47e-03	36
GO:0046456	GO:0046456	icosanoid biosynthetic process	13/1028	36/8135	2.86	2.71e-04	1.47e-03	36
GO:1900274	GO:1900274	regulation of phospholipase C activity	13/1028	36/8135	2.86	2.71e-04	1.47e-03	36
GO:0097190	GO:0097190	apoptotic signaling pathway	50/1028	243/8135	1.63	2.74e-04	1.48e-03	243
GO:0001525	GO:0001525	angiogenesis	60/1028	306/8135	1.55	2.78e-04	1.50e-03	306
GO:0043491	GO:0043491	protein kinase B signaling	34/1028	147/8135	1.83	2.81e-04	1.52e-03	147
GO:0030890	GO:0030890	positive regulation of B cell proliferation	12/1028	32/8135	2.97	3.10e-04	1.66e-03	32
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	12/1028	32/8135	2.97	3.10e-04	1.66e-03	32
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	12/1028	32/8135	2.97	3.10e-04	1.66e-03	32
GO:0001562	GO:0001562	response to protozoan	8/1028	16/8135	3.96	3.19e-04	1.71e-03	16
GO:0032147	GO:0032147	activation of protein kinase activity	38/1028	172/8135	1.75	3.41e-04	1.82e-03	172
GO:0001894	GO:0001894	tissue homeostasis	33/1028	143/8135	1.83	3.59e-04	1.92e-03	143
GO:0006509	GO:0006509	membrane protein ectodomain proteolysis	9/1028	20/8135	3.56	3.62e-04	1.92e-03	20
GO:0030865	GO:0030865	cortical cytoskeleton organization	9/1028	20/8135	3.56	3.62e-04	1.92e-03	20
GO:0033028	GO:0033028	myeloid cell apoptotic process	9/1028	20/8135	3.56	3.62e-04	1.92e-03	20
GO:0030224	GO:0030224	monocyte differentiation	10/1028	24/8135	3.30	3.65e-04	1.93e-03	24
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	10/1028	24/8135	3.30	3.65e-04	1.93e-03	24
GO:1903131	GO:1903131	mononuclear cell differentiation	10/1028	24/8135	3.30	3.65e-04	1.93e-03	24
GO:0070527	GO:0070527	platelet aggregation	13/1028	37/8135	2.78	3.70e-04	1.96e-03	37
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	22/1028	82/8135	2.12	3.87e-04	2.04e-03	82
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	34/1028	150/8135	1.79	4.19e-04	2.21e-03	150
GO:0002643	GO:0002643	regulation of tolerance induction	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0002710	GO:0002710	negative regulation of T cell mediated immunity	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0002830	GO:0002830	positive regulation of type 2 immune response	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0010919	GO:0010919	regulation of inositol phosphate biosynthetic process	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0032740	GO:0032740	positive regulation of interleukin-17 production	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0033033	GO:0033033	negative regulation of myeloid cell apoptotic process	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:2000319	GO:2000319	regulation of T-helper 17 cell differentiation	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:2000484	GO:2000484	positive regulation of interleukin-8 secretion	7/1028	13/8135	4.26	4.33e-04	2.25e-03	13
GO:0071902	GO:0071902	positive regulation of protein serine/threonine kinase activity	39/1028	180/8135	1.71	4.34e-04	2.25e-03	180
GO:0035587	GO:0035587	purinergic receptor signaling pathway	11/1028	29/8135	3.00	4.91e-04	2.54e-03	29
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	30/1028	128/8135	1.85	4.96e-04	2.56e-03	128
GO:0048017	GO:0048017	inositol lipid-mediated signaling	25/1028	100/8135	1.98	5.17e-04	2.67e-03	100
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	8/1028	17/8135	3.72	5.36e-04	2.71e-03	17
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	8/1028	17/8135	3.72	5.36e-04	2.71e-03	17
GO:0002517	GO:0002517	T cell tolerance induction	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0010759	GO:0010759	positive regulation of macrophage chemotaxis	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0032727	GO:0032727	positive regulation of interferon-alpha production	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0042535	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0045060	GO:0045060	negative thymic T cell selection	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0045063	GO:0045063	T-helper 1 cell differentiation	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0045591	GO:0045591	positive regulation of regulatory T cell differentiation	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0045623	GO:0045623	negative regulation of T-helper cell differentiation	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0051044	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	6/1028	10/8135	4.75	5.36e-04	2.71e-03	10
GO:0002534	GO:0002534	cytokine production involved in inflammatory response	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0002675	GO:0002675	positive regulation of acute inflammatory response	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0043277	GO:0043277	apoptotic cell clearance	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0070229	GO:0070229	negative regulation of lymphocyte apoptotic process	10/1028	25/8135	3.17	5.40e-04	2.71e-03	25
GO:0043552	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	9/1028	21/8135	3.39	5.63e-04	2.81e-03	21
GO:1902932	GO:1902932	positive regulation of alcohol biosynthetic process	9/1028	21/8135	3.39	5.63e-04	2.81e-03	21
GO:0033627	GO:0033627	cell adhesion mediated by integrin	15/1028	48/8135	2.47	5.71e-04	2.85e-03	48
GO:0001659	GO:0001659	temperature homeostasis	25/1028	101/8135	1.96	6.07e-04	3.02e-03	101
GO:1903169	GO:1903169	regulation of calcium ion transmembrane transport	24/1028	96/8135	1.98	6.64e-04	3.29e-03	96
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	27/1028	113/8135	1.89	6.77e-04	3.36e-03	113
GO:0002437	GO:0002437	inflammatory response to antigenic stimulus	11/1028	30/8135	2.90	6.88e-04	3.40e-03	30
GO:0016485	GO:0016485	protein processing	33/1028	148/8135	1.76	6.90e-04	3.40e-03	148
GO:0007264	GO:0007264	small GTPase mediated signal transduction	51/1028	259/8135	1.56	7.07e-04	3.48e-03	259
GO:0050830	GO:0050830	defense response to Gram-positive bacterium	17/1028	59/8135	2.28	7.20e-04	3.54e-03	59
GO:0045639	GO:0045639	positive regulation of myeloid cell differentiation	16/1028	54/8135	2.34	7.31e-04	3.59e-03	54
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	16/1028	54/8135	2.34	7.31e-04	3.59e-03	54
GO:0032645	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	7/1028	14/8135	3.96	7.72e-04	3.77e-03	14
GO:0045191	GO:0045191	regulation of isotype switching	7/1028	14/8135	3.96	7.72e-04	3.77e-03	14
GO:0048305	GO:0048305	immunoglobulin secretion	7/1028	14/8135	3.96	7.72e-04	3.77e-03	14
GO:0002369	GO:0002369	T cell cytokine production	10/1028	26/8135	3.04	7.79e-04	3.79e-03	26
GO:0007202	GO:0007202	activation of phospholipase C activity	10/1028	26/8135	3.04	7.79e-04	3.79e-03	26
GO:1903428	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	10/1028	26/8135	3.04	7.79e-04	3.79e-03	26
GO:0034599	GO:0034599	cellular response to oxidative stress	27/1028	114/8135	1.87	7.83e-04	3.80e-03	114
GO:0043550	GO:0043550	regulation of lipid kinase activity	12/1028	35/8135	2.71	7.98e-04	3.86e-03	35
GO:0006644	GO:0006644	phospholipid metabolic process	46/1028	229/8135	1.59	8.19e-04	3.96e-03	229
GO:0016445	GO:0016445	somatic diversification of immunoglobulins	9/1028	22/8135	3.24	8.46e-04	4.06e-03	22
GO:0032692	GO:0032692	negative regulation of interleukin-1 production	9/1028	22/8135	3.24	8.46e-04	4.06e-03	22
GO:0038083	GO:0038083	peptidyl-tyrosine autophosphorylation	9/1028	22/8135	3.24	8.46e-04	4.06e-03	22
GO:0050691	GO:0050691	regulation of defense response to virus by host	9/1028	22/8135	3.24	8.46e-04	4.06e-03	22
GO:0052548	GO:0052548	regulation of endopeptidase activity	48/1028	242/8135	1.57	8.51e-04	4.08e-03	242
GO:0009612	GO:0009612	response to mechanical stimulus	30/1028	132/8135	1.80	8.54e-04	4.09e-03	132
GO:0002335	GO:0002335	mature B cell differentiation	8/1028	18/8135	3.52	8.59e-04	4.09e-03	18
GO:0010758	GO:0010758	regulation of macrophage chemotaxis	8/1028	18/8135	3.52	8.59e-04	4.09e-03	18
GO:0032958	GO:0032958	inositol phosphate biosynthetic process	8/1028	18/8135	3.52	8.59e-04	4.09e-03	18
GO:1904646	GO:1904646	cellular response to amyloid-beta	8/1028	18/8135	3.52	8.59e-04	4.09e-03	18
GO:0032722	GO:0032722	positive regulation of chemokine production	13/1028	40/8135	2.57	8.70e-04	4.14e-03	40
GO:0042136	GO:0042136	neurotransmitter biosynthetic process	17/1028	60/8135	2.24	8.88e-04	4.22e-03	60
GO:0048015	GO:0048015	phosphatidylinositol-mediated signaling	24/1028	98/8135	1.94	9.11e-04	4.32e-03	98
GO:0060193	GO:0060193	positive regulation of lipase activity	15/1028	50/8135	2.37	9.21e-04	4.36e-03	50
GO:0032088	GO:0032088	negative regulation of NF-kappaB transcription factor activity	11/1028	31/8135	2.81	9.47e-04	4.48e-03	31
GO:0031589	GO:0031589	cell-substrate adhesion	42/1028	206/8135	1.61	9.98e-04	4.71e-03	206
GO:0010715	GO:0010715	regulation of extracellular matrix disassembly	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0010819	GO:0010819	regulation of T cell chemotaxis	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0016045	GO:0016045	detection of bacterium	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0044126	GO:0044126	regulation of growth of symbiont in host	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0044130	GO:0044130	negative regulation of growth of symbiont in host	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0071361	GO:0071361	cellular response to ethanol	6/1028	11/8135	4.32	1.05e-03	4.93e-03	11
GO:0046850	GO:0046850	regulation of bone remodeling	12/1028	36/8135	2.64	1.06e-03	4.96e-03	36
GO:0002262	GO:0002262	myeloid cell homeostasis	17/1028	61/8135	2.21	1.09e-03	5.09e-03	61
GO:0000187	GO:0000187	activation of MAPK activity	22/1028	88/8135	1.98	1.10e-03	5.10e-03	88
GO:0097696	GO:0097696	STAT cascade	22/1028	88/8135	1.98	1.10e-03	5.10e-03	88
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	10/1028	27/8135	2.93	1.10e-03	5.10e-03	27
GO:0048246	GO:0048246	macrophage chemotaxis	10/1028	27/8135	2.93	1.10e-03	5.10e-03	27
GO:0032370	GO:0032370	positive regulation of lipid transport	13/1028	41/8135	2.51	1.13e-03	5.23e-03	41
GO:0034103	GO:0034103	regulation of tissue remodeling	15/1028	51/8135	2.33	1.16e-03	5.35e-03	51
GO:0051224	GO:0051224	negative regulation of protein transport	23/1028	94/8135	1.94	1.17e-03	5.41e-03	94
GO:0043902	GO:0043902	positive regulation of multi-organism process	19/1028	72/8135	2.09	1.17e-03	5.42e-03	72
GO:0035588	GO:0035588	G protein-coupled purinergic receptor signaling pathway	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:0042036	GO:0042036	negative regulation of cytokine biosynthetic process	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:0042554	GO:0042554	superoxide anion generation	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:0045429	GO:0045429	positive regulation of nitric oxide biosynthetic process	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:0090218	GO:0090218	positive regulation of lipid kinase activity	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:1900015	GO:1900015	regulation of cytokine production involved in inflammatory response	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:1904407	GO:1904407	positive regulation of nitric oxide metabolic process	9/1028	23/8135	3.10	1.24e-03	5.65e-03	23
GO:0002762	GO:0002762	negative regulation of myeloid leukocyte differentiation	11/1028	32/8135	2.72	1.28e-03	5.83e-03	32
GO:0045620	GO:0045620	negative regulation of lymphocyte differentiation	11/1028	32/8135	2.72	1.28e-03	5.83e-03	32
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	7/1028	15/8135	3.69	1.29e-03	5.84e-03	15
GO:0042095	GO:0042095	interferon-gamma biosynthetic process	7/1028	15/8135	3.69	1.29e-03	5.84e-03	15
GO:0046639	GO:0046639	negative regulation of alpha-beta T cell differentiation	7/1028	15/8135	3.69	1.29e-03	5.84e-03	15
GO:0051043	GO:0051043	regulation of membrane protein ectodomain proteolysis	7/1028	15/8135	3.69	1.29e-03	5.84e-03	15
GO:0001782	GO:0001782	B cell homeostasis	8/1028	19/8135	3.33	1.32e-03	5.95e-03	19
GO:0002724	GO:0002724	regulation of T cell cytokine production	8/1028	19/8135	3.33	1.32e-03	5.95e-03	19
GO:0045920	GO:0045920	negative regulation of exocytosis	8/1028	19/8135	3.33	1.32e-03	5.95e-03	19
GO:1904950	GO:1904950	negative regulation of establishment of protein localization	23/1028	95/8135	1.92	1.36e-03	6.13e-03	95
GO:0051056	GO:0051056	regulation of small GTPase mediated signal transduction	35/1028	166/8135	1.67	1.39e-03	6.25e-03	166
GO:0007259	GO:0007259	JAK-STAT cascade	21/1028	84/8135	1.98	1.41e-03	6.31e-03	84
GO:0045766	GO:0045766	positive regulation of angiogenesis	25/1028	107/8135	1.85	1.48e-03	6.64e-03	107
GO:0046006	GO:0046006	regulation of activated T cell proliferation	10/1028	28/8135	2.83	1.52e-03	6.79e-03	28
GO:0010959	GO:0010959	regulation of metal ion transport	49/1028	255/8135	1.52	1.55e-03	6.91e-03	255
GO:0046488	GO:0046488	phosphatidylinositol metabolic process	27/1028	119/8135	1.80	1.56e-03	6.95e-03	119
GO:0051701	GO:0051701	interaction with host	21/1028	85/8135	1.96	1.65e-03	7.34e-03	85
GO:0043406	GO:0043406	positive regulation of MAP kinase activity	33/1028	156/8135	1.67	1.78e-03	7.89e-03	156
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	12/1028	38/8135	2.50	1.81e-03	8.00e-03	38
GO:0001935	GO:0001935	endothelial cell proliferation	20/1028	80/8135	1.98	1.81e-03	8.02e-03	80
GO:0002374	GO:0002374	cytokine secretion involved in immune response	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0002726	GO:0002726	positive regulation of T cell cytokine production	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0032728	GO:0032728	positive regulation of interferon-beta production	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0033004	GO:0033004	negative regulation of mast cell activation	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0044144	GO:0044144	modulation of growth of symbiont involved in interaction with host	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0044146	GO:0044146	negative regulation of growth of symbiont involved in interaction with host	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0045655	GO:0045655	regulation of monocyte differentiation	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0060732	GO:0060732	positive regulation of inositol phosphate biosynthetic process	6/1028	12/8135	3.96	1.88e-03	8.24e-03	12
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	21/1028	86/8135	1.93	1.93e-03	8.43e-03	86
GO:2000377	GO:2000377	regulation of reactive oxygen species metabolic process	21/1028	86/8135	1.93	1.93e-03	8.43e-03	86
GO:0043405	GO:0043405	regulation of MAP kinase activity	39/1028	194/8135	1.59	1.95e-03	8.44e-03	194
GO:0051604	GO:0051604	protein maturation	34/1028	163/8135	1.65	1.96e-03	8.44e-03	163
GO:0002204	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:0002208	GO:0002208	somatic diversification of immunoglobulins involved in immune response	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:0016447	GO:0016447	somatic recombination of immunoglobulin gene segments	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:0045190	GO:0045190	isotype switching	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:0090322	GO:0090322	regulation of superoxide metabolic process	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:1902624	GO:1902624	positive regulation of neutrophil migration	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:1904645	GO:1904645	response to amyloid-beta	8/1028	20/8135	3.17	1.96e-03	8.44e-03	20
GO:0070613	GO:0070613	regulation of protein processing	19/1028	75/8135	2.00	1.98e-03	8.51e-03	75
GO:0052547	GO:0052547	regulation of peptidase activity	49/1028	258/8135	1.50	2.00e-03	8.58e-03	258
GO:0006929	GO:0006929	substrate-dependent cell migration	7/1028	16/8135	3.46	2.05e-03	8.77e-03	16
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	7/1028	16/8135	3.46	2.05e-03	8.77e-03	16
GO:0050798	GO:0050798	activated T cell proliferation	10/1028	29/8135	2.73	2.06e-03	8.80e-03	29
GO:0051482	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	10/1028	29/8135	2.73	2.06e-03	8.80e-03	29
GO:0032368	GO:0032368	regulation of lipid transport	18/1028	70/8135	2.03	2.15e-03	9.18e-03	70
GO:0007260	GO:0007260	tyrosine phosphorylation of STAT protein	15/1028	54/8135	2.20	2.18e-03	9.28e-03	54
GO:0007200	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	21/1028	87/8135	1.91	2.25e-03	9.59e-03	87
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	14/1028	49/8135	2.26	2.27e-03	9.64e-03	49
GO:0014015	GO:0014015	positive regulation of gliogenesis	12/1028	39/8135	2.43	2.31e-03	9.80e-03	39
GO:1903317	GO:1903317	regulation of protein maturation	19/1028	76/8135	1.98	2.33e-03	9.87e-03	76
GO:1904062	GO:1904062	regulation of cation transmembrane transport	41/1028	209/8135	1.55	2.44e-03	1.03e-02	209
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	18/1028	71/8135	2.01	2.55e-03	1.08e-02	71
GO:0045765	GO:0045765	regulation of angiogenesis	36/1028	178/8135	1.60	2.57e-03	1.08e-02	178
GO:0032642	GO:0032642	regulation of chemokine production	15/1028	55/8135	2.16	2.65e-03	1.11e-02	55
GO:0070670	GO:0070670	response to interleukin-4	8/1028	21/8135	3.01	2.82e-03	1.18e-02	21
GO:1904427	GO:1904427	positive regulation of calcium ion transmembrane transport	13/1028	45/8135	2.29	2.89e-03	1.21e-02	45
GO:0010524	GO:0010524	positive regulation of calcium ion transport into cytosol	12/1028	40/8135	2.37	2.93e-03	1.23e-02	40
GO:0120162	GO:0120162	positive regulation of cold-induced thermogenesis	16/1028	61/8135	2.08	2.99e-03	1.25e-02	61
GO:0043433	GO:0043433	negative regulation of DNA-binding transcription factor activity	18/1028	72/8135	1.98	3.01e-03	1.25e-02	72
GO:0042133	GO:0042133	neurotransmitter metabolic process	21/1028	89/8135	1.87	3.03e-03	1.26e-02	89
GO:0001516	GO:0001516	prostaglandin biosynthetic process	7/1028	17/8135	3.26	3.10e-03	1.28e-02	17
GO:0032608	GO:0032608	interferon-beta production	7/1028	17/8135	3.26	3.10e-03	1.28e-02	17
GO:0032648	GO:0032648	regulation of interferon-beta production	7/1028	17/8135	3.26	3.10e-03	1.28e-02	17
GO:0032703	GO:0032703	negative regulation of interleukin-2 production	7/1028	17/8135	3.26	3.10e-03	1.28e-02	17
GO:0046457	GO:0046457	prostanoid biosynthetic process	7/1028	17/8135	3.26	3.10e-03	1.28e-02	17
GO:0007040	GO:0007040	lysosome organization	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0032725	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0045780	GO:0045780	positive regulation of bone resorption	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0046852	GO:0046852	positive regulation of bone remodeling	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0050858	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0080171	GO:0080171	lytic vacuole organization	6/1028	13/8135	3.65	3.13e-03	1.28e-02	13
GO:0046777	GO:0046777	protein autophosphorylation	24/1028	107/8135	1.77	3.25e-03	1.33e-02	107
GO:1904018	GO:1904018	positive regulation of vasculature development	26/1028	119/8135	1.73	3.29e-03	1.35e-02	119
GO:0002200	GO:0002200	somatic diversification of immune receptors	9/1028	26/8135	2.74	3.33e-03	1.36e-02	26
GO:0033619	GO:0033619	membrane protein proteolysis	9/1028	26/8135	2.74	3.33e-03	1.36e-02	26
GO:0046330	GO:0046330	positive regulation of JNK cascade	20/1028	84/8135	1.88	3.36e-03	1.37e-02	84
GO:2000117	GO:2000117	negative regulation of cysteine-type endopeptidase activity	13/1028	46/8135	2.24	3.57e-03	1.45e-02	46
GO:1904894	GO:1904894	positive regulation of STAT cascade	16/1028	62/8135	2.04	3.57e-03	1.45e-02	62
GO:0071260	GO:0071260	cellular response to mechanical stimulus	12/1028	41/8135	2.32	3.68e-03	1.49e-02	41
GO:1902930	GO:1902930	regulation of alcohol biosynthetic process	12/1028	41/8135	2.32	3.68e-03	1.49e-02	41
GO:0032963	GO:0032963	collagen metabolic process	17/1028	68/8135	1.98	3.88e-03	1.57e-02	68
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	8/1028	22/8135	2.88	3.95e-03	1.60e-02	22
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	14/1028	52/8135	2.13	4.13e-03	1.67e-02	52
GO:2000379	GO:2000379	positive regulation of reactive oxygen species metabolic process	14/1028	52/8135	2.13	4.13e-03	1.67e-02	52
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	16/1028	63/8135	2.01	4.24e-03	1.71e-02	63
GO:0008347	GO:0008347	glial cell migration	9/1028	27/8135	2.64	4.44e-03	1.78e-02	27
GO:0002691	GO:0002691	regulation of cellular extravasation	7/1028	18/8135	3.08	4.53e-03	1.82e-02	18
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	7/1028	18/8135	3.08	4.53e-03	1.82e-02	18
GO:0043154	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	12/1028	42/8135	2.26	4.57e-03	1.83e-02	42
GO:0001771	GO:0001771	immunological synapse formation	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0001780	GO:0001780	neutrophil homeostasis	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0002418	GO:0002418	immune response to tumor cell	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0002923	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0010820	GO:0010820	positive regulation of T cell chemotaxis	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0042362	GO:0042362	fat-soluble vitamin biosynthetic process	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0045830	GO:0045830	positive regulation of isotype switching	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0060252	GO:0060252	positive regulation of glial cell proliferation	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0071404	GO:0071404	cellular response to low-density lipoprotein particle stimulus	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:2001185	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	5/1028	10/8135	3.96	4.65e-03	1.84e-02	10
GO:0033628	GO:0033628	regulation of cell adhesion mediated by integrin	10/1028	32/8135	2.47	4.66e-03	1.84e-02	32
GO:0031331	GO:0031331	positive regulation of cellular catabolic process	24/1028	110/8135	1.73	4.73e-03	1.86e-02	110
GO:0032928	GO:0032928	regulation of superoxide anion generation	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:0043302	GO:0043302	positive regulation of leukocyte degranulation	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:0044117	GO:0044117	growth of symbiont in host	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:0045072	GO:0045072	regulation of interferon-gamma biosynthetic process	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:0045911	GO:0045911	positive regulation of DNA recombination	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:1903306	GO:1903306	negative regulation of regulated secretory pathway	6/1028	14/8135	3.39	4.89e-03	1.91e-02	14
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	14/1028	53/8135	2.09	4.98e-03	1.94e-02	53
GO:0034109	GO:0034109	homotypic cell-cell adhesion	14/1028	53/8135	2.09	4.98e-03	1.94e-02	53
GO:0030193	GO:0030193	regulation of blood coagulation	16/1028	64/8135	1.98	5.01e-03	1.95e-02	64
GO:1900046	GO:1900046	regulation of hemostasis	16/1028	64/8135	1.98	5.01e-03	1.95e-02	64
GO:0070304	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	22/1028	99/8135	1.76	5.31e-03	2.07e-02	99
GO:0046854	GO:0046854	phosphatidylinositol phosphorylation	17/1028	70/8135	1.92	5.33e-03	2.07e-02	70
GO:0002639	GO:0002639	positive regulation of immunoglobulin production	8/1028	23/8135	2.75	5.39e-03	2.09e-02	23
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	8/1028	23/8135	2.75	5.39e-03	2.09e-02	23
GO:0050832	GO:0050832	defense response to fungus	8/1028	23/8135	2.75	5.39e-03	2.09e-02	23
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	15/1028	59/8135	2.01	5.48e-03	2.12e-02	59
GO:0006650	GO:0006650	glycerophospholipid metabolic process	35/1028	180/8135	1.54	5.65e-03	2.18e-02	180
GO:0035690	GO:0035690	cellular response to drug	35/1028	180/8135	1.54	5.65e-03	2.18e-02	180
GO:0106106	GO:0106106	cold-induced thermogenesis	19/1028	82/8135	1.83	5.76e-03	2.22e-02	82
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	19/1028	82/8135	1.83	5.76e-03	2.22e-02	82
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	9/1028	28/8135	2.54	5.82e-03	2.24e-02	28
GO:0051281	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	9/1028	28/8135	2.54	5.82e-03	2.24e-02	28
GO:0019915	GO:0019915	lipid storage	11/1028	38/8135	2.29	5.85e-03	2.24e-02	38
GO:0043647	GO:0043647	inositol phosphate metabolic process	11/1028	38/8135	2.29	5.85e-03	2.24e-02	38
GO:0050818	GO:0050818	regulation of coagulation	16/1028	65/8135	1.95	5.88e-03	2.25e-02	65
GO:1903305	GO:1903305	regulation of regulated secretory pathway	22/1028	100/8135	1.74	6.01e-03	2.30e-02	100
GO:0045672	GO:0045672	positive regulation of osteoclast differentiation	7/1028	19/8135	2.92	6.40e-03	2.44e-02	19
GO:0071353	GO:0071353	cellular response to interleukin-4	7/1028	19/8135	2.92	6.40e-03	2.44e-02	19
GO:0046834	GO:0046834	lipid phosphorylation	18/1028	77/8135	1.85	6.44e-03	2.45e-02	77
GO:0043270	GO:0043270	positive regulation of ion transport	36/1028	188/8135	1.52	6.51e-03	2.48e-02	188
GO:0017157	GO:0017157	regulation of exocytosis	26/1028	125/8135	1.65	6.55e-03	2.49e-02	125
GO:0048661	GO:0048661	positive regulation of smooth muscle cell proliferation	14/1028	55/8135	2.01	7.09e-03	2.69e-02	55
GO:0002562	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:0009164	GO:0009164	nucleoside catabolic process	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:0010955	GO:0010955	negative regulation of protein processing	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:0016444	GO:0016444	somatic cell DNA recombination	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:0045806	GO:0045806	negative regulation of endocytosis	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:1903318	GO:1903318	negative regulation of protein maturation	8/1028	24/8135	2.64	7.21e-03	2.72e-02	24
GO:0002313	GO:0002313	mature B cell differentiation involved in immune response	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:0006837	GO:0006837	serotonin transport	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:0030947	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:0044110	GO:0044110	growth involved in symbiotic interaction	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:0044116	GO:0044116	growth of symbiont involved in interaction with host	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:1904037	GO:1904037	positive regulation of epithelial cell apoptotic process	6/1028	15/8135	3.17	7.29e-03	2.73e-02	15
GO:0033089	GO:0033089	positive regulation of T cell differentiation in thymus	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:0034162	GO:0034162	toll-like receptor 9 signaling pathway	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:0043011	GO:0043011	myeloid dendritic cell differentiation	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:0043374	GO:0043374	CD8-positive, alpha-beta T cell differentiation	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:0051767	GO:0051767	nitric-oxide synthase biosynthetic process	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:0051769	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:1904469	GO:1904469	positive regulation of tumor necrosis factor secretion	5/1028	11/8135	3.60	7.64e-03	2.84e-02	11
GO:1901136	GO:1901136	carbohydrate derivative catabolic process	22/1028	102/8135	1.71	7.67e-03	2.84e-02	102
GO:0051896	GO:0051896	regulation of protein kinase B signaling	27/1028	133/8135	1.61	7.91e-03	2.93e-02	133
GO:0002920	GO:0002920	regulation of humoral immune response	14/1028	56/8135	1.98	8.38e-03	3.10e-02	56
GO:0032814	GO:0032814	regulation of natural killer cell activation	7/1028	20/8135	2.77	8.79e-03	3.24e-02	20
GO:0046135	GO:0046135	pyrimidine nucleoside catabolic process	7/1028	20/8135	2.77	8.79e-03	3.24e-02	20
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	7/1028	20/8135	2.77	8.79e-03	3.24e-02	20
GO:0001960	GO:0001960	negative regulation of cytokine-mediated signaling pathway	10/1028	35/8135	2.26	9.32e-03	3.43e-02	35
GO:0010573	GO:0010573	vascular endothelial growth factor production	8/1028	25/8135	2.53	9.45e-03	3.47e-02	25
GO:0010883	GO:0010883	regulation of lipid storage	8/1028	25/8135	2.53	9.45e-03	3.47e-02	25
GO:0070741	GO:0070741	response to interleukin-6	8/1028	25/8135	2.53	9.45e-03	3.47e-02	25
GO:0034767	GO:0034767	positive regulation of ion transmembrane transport	22/1028	104/8135	1.67	9.67e-03	3.54e-02	104
GO:0032874	GO:0032874	positive regulation of stress-activated MAPK cascade	21/1028	98/8135	1.70	9.76e-03	3.57e-02	98
GO:0032616	GO:0032616	interleukin-13 production	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:0032691	GO:0032691	negative regulation of interleukin-1 beta production	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:0042454	GO:0042454	ribonucleoside catabolic process	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:1904467	GO:1904467	regulation of tumor necrosis factor secretion	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:1990774	GO:1990774	tumor necrosis factor secretion	6/1028	16/8135	2.97	1.04e-02	3.79e-02	16
GO:0097006	GO:0097006	regulation of plasma lipoprotein particle levels	13/1028	52/8135	1.98	1.09e-02	3.94e-02	52
GO:1990845	GO:1990845	adaptive thermogenesis	19/1028	87/8135	1.73	1.11e-02	4.01e-02	87
GO:0060761	GO:0060761	negative regulation of response to cytokine stimulus	10/1028	36/8135	2.20	1.15e-02	4.14e-02	36
GO:0071825	GO:0071825	protein-lipid complex subunit organization	10/1028	36/8135	2.20	1.15e-02	4.14e-02	36
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0009110	GO:0009110	vitamin biosynthetic process	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0032373	GO:0032373	positive regulation of sterol transport	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0032376	GO:0032376	positive regulation of cholesterol transport	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0046133	GO:0046133	pyrimidine ribonucleoside catabolic process	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0051023	GO:0051023	regulation of immunoglobulin secretion	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0060099	GO:0060099	regulation of phagocytosis, engulfment	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:1904994	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:1905153	GO:1905153	regulation of membrane invagination	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:2000353	GO:2000353	positive regulation of endothelial cell apoptotic process	5/1028	12/8135	3.30	1.18e-02	4.19e-02	12
GO:0006692	GO:0006692	prostanoid metabolic process	7/1028	21/8135	2.64	1.18e-02	4.19e-02	21
GO:0006693	GO:0006693	prostaglandin metabolic process	7/1028	21/8135	2.64	1.18e-02	4.19e-02	21
GO:0034105	GO:0034105	positive regulation of tissue remodeling	7/1028	21/8135	2.64	1.18e-02	4.19e-02	21
GO:0071354	GO:0071354	cellular response to interleukin-6	7/1028	21/8135	2.64	1.18e-02	4.19e-02	21
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	9/1028	31/8135	2.30	1.20e-02	4.26e-02	31
GO:0050792	GO:0050792	regulation of viral process	16/1028	70/8135	1.81	1.23e-02	4.36e-02	70
GO:1904064	GO:1904064	positive regulation of cation transmembrane transport	20/1028	94/8135	1.68	1.24e-02	4.40e-02	94
GO:0034764	GO:0034764	positive regulation of transmembrane transport	25/1028	125/8135	1.58	1.25e-02	4.41e-02	125
GO:1904892	GO:1904892	regulation of STAT cascade	18/1028	82/8135	1.74	1.25e-02	4.43e-02	82
GO:0050922	GO:0050922	negative regulation of chemotaxis	11/1028	42/8135	2.07	1.30e-02	4.59e-02	42
GO:1903034	GO:1903034	regulation of response to wounding	22/1028	107/8135	1.63	1.34e-02	4.74e-02	107
GO:0046579	GO:0046579	positive regulation of Ras protein signal transduction	10/1028	37/8135	2.14	1.40e-02	4.94e-02	37
GO:0030282	GO:0030282	bone mineralization	17/1028	77/8135	1.75	1.42e-02	4.99e-02	77

Factor 6 : 1 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0060271	GO:0060271	cilium assembly	83/3587	123/8135	1.53	1.17e-07	0.000266	123

Factor 8 : 2 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0007156	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	81/2982	144/8135	1.53	1.10e-06	0.00517	144
GO:0003341	GO:0003341	cilium movement	31/2982	46/8135	1.84	2.15e-05	0.04666	46

Factor 9 : 77 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0044782	GO:0044782	cilium organization	89/2640	132/8135	2.08	1.18e-16	5.14e-13	132
GO:0060271	GO:0060271	cilium assembly	84/2640	123/8135	2.10	2.64e-16	5.73e-13	123
GO:0003341	GO:0003341	cilium movement	41/2640	46/8135	2.75	1.55e-15	1.40e-12	46
GO:0035082	GO:0035082	axoneme assembly	41/2640	46/8135	2.75	1.55e-15	1.40e-12	46
GO:0007017	GO:0007017	microtubule-based process	162/2640	298/8135	1.68	1.61e-15	1.40e-12	298
GO:0007018	GO:0007018	microtubule-based movement	79/2640	119/8135	2.05	2.36e-14	1.71e-11	119
GO:0120031	GO:0120031	plasma membrane bounded cell projection assembly	124/2640	222/8135	1.72	2.87e-13	1.78e-10	222
GO:0001578	GO:0001578	microtubule bundle formation	48/2640	62/8135	2.39	3.87e-13	2.10e-10	62
GO:0030031	GO:0030031	cell projection assembly	127/2640	231/8135	1.69	6.94e-13	3.34e-10	231
GO:0099504	GO:0099504	synaptic vesicle cycle	77/2640	122/8135	1.94	2.63e-12	1.14e-09	122
GO:0099003	GO:0099003	vesicle-mediated transport in synapse	73/2640	115/8135	1.96	6.50e-12	2.56e-09	115
GO:0007269	GO:0007269	neurotransmitter secretion	72/2640	114/8135	1.95	1.29e-11	4.32e-09	114
GO:0099643	GO:0099643	signal release from synapse	72/2640	114/8135	1.95	1.29e-11	4.32e-09	114
GO:0097479	GO:0097479	synaptic vesicle localization	66/2640	102/8135	1.99	1.91e-11	5.81e-09	102
GO:0017156	GO:0017156	calcium ion regulated exocytosis	65/2640	100/8135	2.00	2.01e-11	5.81e-09	100
GO:0070286	GO:0070286	axonemal dynein complex assembly	24/2640	25/8135	2.96	2.99e-11	8.11e-09	25
GO:0017158	GO:0017158	regulation of calcium ion-dependent exocytosis	50/2640	72/8135	2.14	1.20e-10	3.07e-08	72
GO:0006836	GO:0006836	neurotransmitter transport	103/2640	188/8135	1.69	1.42e-10	3.43e-08	188
GO:0048489	GO:0048489	synaptic vesicle transport	60/2640	93/8135	1.99	1.89e-10	4.10e-08	93
GO:0097480	GO:0097480	establishment of synaptic vesicle localization	60/2640	93/8135	1.99	1.89e-10	4.10e-08	93
GO:0016079	GO:0016079	synaptic vesicle exocytosis	53/2640	81/8135	2.02	1.02e-09	1.77e-07	81
GO:0000226	GO:0000226	microtubule cytoskeleton organization	114/2640	224/8135	1.57	5.35e-09	8.59e-07	224
GO:0098693	GO:0098693	regulation of synaptic vesicle cycle	47/2640	72/8135	2.01	1.02e-08	1.48e-06	72
GO:0051648	GO:0051648	vesicle localization	75/2640	134/8135	1.72	1.35e-08	1.88e-06	134
GO:0051650	GO:0051650	establishment of vesicle localization	69/2640	122/8135	1.74	2.89e-08	3.80e-06	122
GO:0001505	GO:0001505	regulation of neurotransmitter levels	111/2640	225/8135	1.52	7.51e-08	9.30e-06	225
GO:1902803	GO:1902803	regulation of synaptic vesicle transport	38/2640	57/8135	2.05	1.15e-07	1.25e-05	57
GO:2000300	GO:2000300	regulation of synaptic vesicle exocytosis	36/2640	53/8135	2.09	1.20e-07	1.27e-05	53
GO:0045956	GO:0045956	positive regulation of calcium ion-dependent exocytosis	18/2640	20/8135	2.77	1.40e-07	1.41e-05	20
GO:0046928	GO:0046928	regulation of neurotransmitter secretion	45/2640	72/8135	1.93	1.45e-07	1.43e-05	72
GO:0036158	GO:0036158	outer dynein arm assembly	13/2640	13/8135	3.08	4.34e-07	3.84e-05	13
GO:0001539	GO:0001539	cilium or flagellum-dependent cell motility	19/2640	23/8135	2.55	1.01e-06	8.15e-05	23
GO:0060285	GO:0060285	cilium-dependent cell motility	19/2640	23/8135	2.55	1.01e-06	8.15e-05	23
GO:0031338	GO:0031338	regulation of vesicle fusion	16/2640	18/8135	2.74	1.09e-06	8.57e-05	18
GO:0017157	GO:0017157	regulation of exocytosis	66/2640	125/8135	1.63	1.73e-06	1.32e-04	125
GO:0030073	GO:0030073	insulin secretion	68/2640	133/8135	1.58	5.35e-06	3.78e-04	133
GO:0030072	GO:0030072	peptide hormone secretion	81/2640	165/8135	1.51	5.50e-06	3.78e-04	165
GO:1903305	GO:1903305	regulation of regulated secretory pathway	54/2640	100/8135	1.66	6.23e-06	4.17e-04	100
GO:0008306	GO:0008306	associative learning	30/2640	47/8135	1.97	9.57e-06	6.10e-04	47
GO:0051588	GO:0051588	regulation of neurotransmitter transport	52/2640	97/8135	1.65	1.21e-05	7.47e-04	97
GO:0036159	GO:0036159	inner dynein arm assembly	12/2640	13/8135	2.84	1.22e-05	7.47e-04	13
GO:0007368	GO:0007368	determination of left/right symmetry	39/2640	69/8135	1.74	3.02e-05	1.77e-03	69
GO:0003351	GO:0003351	epithelial cilium movement	14/2640	17/8135	2.54	3.26e-05	1.88e-03	17
GO:0044458	GO:0044458	motile cilium assembly	11/2640	12/8135	2.82	3.50e-05	2.00e-03	12
GO:0009855	GO:0009855	determination of bilateral symmetry	41/2640	75/8135	1.68	5.49e-05	3.09e-03	75
GO:0007632	GO:0007632	visual behavior	20/2640	29/8135	2.13	5.96e-05	3.31e-03	29
GO:1990138	GO:1990138	neuron projection extension	48/2640	92/8135	1.61	6.52e-05	3.58e-03	92
GO:0048167	GO:0048167	regulation of synaptic plasticity	57/2640	114/8135	1.54	6.86e-05	3.72e-03	114
GO:0009799	GO:0009799	specification of symmetry	41/2640	76/8135	1.66	8.22e-05	4.35e-03	76
GO:0035418	GO:0035418	protein localization to synapse	25/2640	40/8135	1.93	8.87e-05	4.63e-03	40
GO:0007612	GO:0007612	learning	48/2640	93/8135	1.59	9.28e-05	4.79e-03	93
GO:0045921	GO:0045921	positive regulation of exocytosis	28/2640	47/8135	1.84	1.15e-04	5.77e-03	47
GO:0008542	GO:0008542	visual learning	18/2640	26/8135	2.13	1.31e-04	6.52e-03	26
GO:0140029	GO:0140029	exocytic process	25/2640	41/8135	1.88	1.58e-04	7.76e-03	41
GO:0035249	GO:0035249	synaptic transmission, glutamatergic	38/2640	71/8135	1.65	1.85e-04	8.71e-03	71
GO:0060632	GO:0060632	regulation of microtubule-based movement	12/2640	15/8135	2.47	2.11e-04	9.85e-03	15
GO:1902475	GO:1902475	L-alpha-amino acid transmembrane transport	20/2640	31/8135	1.99	2.44e-04	1.10e-02	31
GO:0090313	GO:0090313	regulation of protein targeting to membrane	14/2640	19/8135	2.27	2.73e-04	1.22e-02	19
GO:0031630	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	9/2640	10/8135	2.77	2.80e-04	1.24e-02	10
GO:1905475	GO:1905475	regulation of protein localization to membrane	41/2640	81/8135	1.56	5.00e-04	2.13e-02	81
GO:0031629	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	12/2640	16/8135	2.31	5.95e-04	2.48e-02	16
GO:0090314	GO:0090314	positive regulation of protein targeting to membrane	12/2640	16/8135	2.31	5.95e-04	2.48e-02	16
GO:0006865	GO:0006865	amino acid transport	43/2640	87/8135	1.52	7.05e-04	2.78e-02	87
GO:0006906	GO:0006906	vesicle fusion	21/2640	35/8135	1.85	7.17e-04	2.78e-02	35
GO:0090174	GO:0090174	organelle membrane fusion	21/2640	35/8135	1.85	7.17e-04	2.78e-02	35
GO:1903307	GO:1903307	positive regulation of regulated secretory pathway	21/2640	35/8135	1.85	7.17e-04	2.78e-02	35
GO:0007215	GO:0007215	glutamate receptor signaling pathway	36/2640	70/8135	1.58	7.38e-04	2.81e-02	70
GO:0099565	GO:0099565	chemical synaptic transmission, postsynaptic	39/2640	78/8135	1.54	9.24e-04	3.34e-02	78
GO:0051966	GO:0051966	regulation of synaptic transmission, glutamatergic	29/2640	54/8135	1.65	9.71e-04	3.48e-02	54
GO:0048675	GO:0048675	axon extension	33/2640	64/8135	1.59	1.14e-03	3.99e-02	64
GO:0008038	GO:0008038	neuron recognition	21/2640	36/8135	1.80	1.20e-03	4.15e-02	36
GO:0021591	GO:0021591	ventricular system development	10/2640	13/8135	2.37	1.29e-03	4.33e-02	13
GO:0021587	GO:0021587	cerebellum morphogenesis	14/2640	21/8135	2.05	1.34e-03	4.45e-02	21
GO:0048640	GO:0048640	negative regulation of developmental growth	34/2640	67/8135	1.56	1.39e-03	4.49e-02	67
GO:0021696	GO:0021696	cerebellar cortex morphogenesis	13/2640	19/8135	2.11	1.40e-03	4.50e-02	19
GO:0099500	GO:0099500	vesicle fusion to plasma membrane	12/2640	17/8135	2.18	1.42e-03	4.54e-02	17
GO:0015807	GO:0015807	L-amino acid transport	23/2640	41/8135	1.73	1.48e-03	4.64e-02	41

Factor 11 : 10 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0006281	GO:0006281	DNA repair	79/3246	130/8135	1.52	1.04e-06	0.00153	130
GO:0030833	GO:0030833	regulation of actin filament polymerization	47/3246	74/8135	1.59	3.21e-05	0.01244	74
GO:0030041	GO:0030041	actin filament polymerization	52/3246	85/8135	1.53	5.55e-05	0.01746	85
GO:0035747	GO:0035747	natural killer cell chemotaxis	10/3246	10/8135	2.51	1.01e-04	0.02352	10
GO:0008064	GO:0008064	regulation of actin polymerization or depolymerization	49/3246	81/8135	1.52	1.35e-04	0.02481	81
GO:0006302	GO:0006302	double-strand break repair	48/3246	79/8135	1.52	1.35e-04	0.02481	79
GO:0072678	GO:0072678	T cell migration	29/3246	43/8135	1.69	2.32e-04	0.03093	43
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	24/3246	34/8135	1.77	2.79e-04	0.03322	34
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	39/3246	63/8135	1.55	3.27e-04	0.03793	63
GO:0010972	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	14/3246	17/8135	2.06	4.33e-04	0.04886	17

Factor 12 : 3 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0070268	GO:0070268	cornification	74/3339	95/8135	1.90	2.02e-13	9.49e-10	95
GO:0031424	GO:0031424	keratinization	88/3339	123/8135	1.74	5.21e-12	1.22e-08	123
GO:0030216	GO:0030216	keratinocyte differentiation	109/3339	162/8135	1.64	8.99e-12	1.41e-08	162

Factor 13 : 281 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	124/752	267/8135	5.02	1.61e-59	6.09e-56	267
GO:0000278	GO:0000278	mitotic cell cycle	135/752	326/8135	4.48	2.05e-57	3.88e-54	326
GO:0022402	GO:0022402	cell cycle process	158/752	470/8135	3.64	6.85e-53	8.63e-50	470
GO:0051301	GO:0051301	cell division	95/752	219/8135	4.69	3.57e-42	3.37e-39	219
GO:0051276	GO:0051276	chromosome organization	128/752	385/8135	3.60	8.24e-42	6.23e-39	385
GO:0007059	GO:0007059	chromosome segregation	68/752	118/8135	6.23	2.17e-40	1.37e-37	118
GO:0044772	GO:0044772	mitotic cell cycle phase transition	79/752	164/8135	5.21	3.51e-39	1.89e-36	164
GO:0044770	GO:0044770	cell cycle phase transition	81/752	177/8135	4.95	4.48e-38	2.12e-35	177
GO:0140014	GO:0140014	mitotic nuclear division	62/752	107/8135	6.27	4.50e-37	1.89e-34	107
GO:0000819	GO:0000819	sister chromatid segregation	49/752	68/8135	7.80	3.06e-36	1.16e-33	68
GO:0000070	GO:0000070	mitotic sister chromatid segregation	44/752	56/8135	8.50	1.87e-35	6.42e-33	56
GO:0000280	GO:0000280	nuclear division	80/752	192/8135	4.51	5.45e-34	1.70e-31	192
GO:0048285	GO:0048285	organelle fission	83/752	206/8135	4.36	5.85e-34	1.70e-31	206
GO:0098813	GO:0098813	nuclear chromosome segregation	58/752	106/8135	5.92	7.56e-33	2.04e-30	106
GO:0006259	GO:0006259	DNA metabolic process	98/752	301/8135	3.52	5.26e-31	1.32e-28	301
GO:0006260	GO:0006260	DNA replication	48/752	77/8135	6.74	5.67e-31	1.34e-28	77
GO:0010564	GO:0010564	regulation of cell cycle process	86/752	243/8135	3.83	3.17e-30	7.04e-28	243
GO:0051726	GO:0051726	regulation of cell cycle	115/752	412/8135	3.02	1.78e-29	3.73e-27	412
GO:0007346	GO:0007346	regulation of mitotic cell cycle	76/752	207/8135	3.97	5.79e-28	1.15e-25	207
GO:0006974	GO:0006974	cellular response to DNA damage stimulus	77/752	230/8135	3.62	2.63e-25	4.96e-23	230
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	52/752	113/8135	4.98	7.75e-25	1.40e-22	113
GO:1901987	GO:1901987	regulation of cell cycle phase transition	54/752	125/8135	4.67	4.23e-24	7.27e-22	125
GO:0006281	GO:0006281	DNA repair	55/752	130/8135	4.58	5.51e-24	9.06e-22	130
GO:0051983	GO:0051983	regulation of chromosome segregation	28/752	35/8135	8.65	2.49e-23	3.93e-21	35
GO:0000075	GO:0000075	cell cycle checkpoint	38/752	67/8135	6.14	1.24e-22	1.87e-20	67
GO:0006261	GO:0006261	DNA-dependent DNA replication	30/752	42/8135	7.73	2.08e-22	3.02e-20	42
GO:0010948	GO:0010948	negative regulation of cell cycle process	45/752	95/8135	5.12	2.77e-22	3.87e-20	95
GO:0071103	GO:0071103	DNA conformation change	50/752	121/8135	4.47	2.39e-21	3.23e-19	121
GO:0044839	GO:0044839	cell cycle G2/M phase transition	38/752	74/8135	5.56	1.42e-20	1.85e-18	74
GO:0045786	GO:0045786	negative regulation of cell cycle	67/752	212/8135	3.42	1.51e-20	1.90e-18	212
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	30/752	47/8135	6.90	3.29e-20	4.01e-18	47
GO:0033045	GO:0033045	regulation of sister chromatid segregation	23/752	28/8135	8.89	7.54e-20	8.91e-18	28
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	32/752	55/8135	6.29	1.03e-19	1.18e-17	55
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	21/752	24/8135	9.47	2.30e-19	2.41e-17	24
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	21/752	24/8135	9.47	2.30e-19	2.41e-17	24
GO:0051306	GO:0051306	mitotic sister chromatid separation	21/752	24/8135	9.47	2.30e-19	2.41e-17	24
GO:0007088	GO:0007088	regulation of mitotic nuclear division	38/752	79/8135	5.20	2.72e-19	2.78e-17	79
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	35/752	68/8135	5.57	4.35e-19	4.33e-17	68
GO:0007051	GO:0007051	spindle organization	30/752	51/8135	6.36	9.57e-19	9.27e-17	51
GO:1905818	GO:1905818	regulation of chromosome separation	21/752	25/8135	9.09	1.31e-18	1.24e-16	25
GO:0051304	GO:0051304	chromosome separation	25/752	36/8135	7.51	2.17e-18	1.97e-16	36
GO:0007052	GO:0007052	mitotic spindle organization	26/752	39/8135	7.21	2.19e-18	1.97e-16	39
GO:0006302	GO:0006302	double-strand break repair	37/752	79/8135	5.07	2.54e-18	2.23e-16	79
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	42/752	101/8135	4.50	3.09e-18	2.65e-16	101
GO:0006310	GO:0006310	DNA recombination	42/752	104/8135	4.37	1.14e-17	9.54e-16	104
GO:0051321	GO:0051321	meiotic cell cycle	50/752	143/8135	3.78	1.17e-17	9.59e-16	143
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	33/752	66/8135	5.41	1.44e-17	1.16e-15	66
GO:0051783	GO:0051783	regulation of nuclear division	40/752	96/8135	4.51	1.84e-17	1.45e-15	96
GO:0031570	GO:0031570	DNA integrity checkpoint	27/752	45/8135	6.49	2.64e-17	2.04e-15	45
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	31/752	60/8135	5.59	4.14e-17	3.13e-15	60
GO:0044843	GO:0044843	cell cycle G1/S phase transition	38/752	91/8135	4.52	1.09e-16	8.09e-15	91
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	18/752	21/8135	9.27	2.05e-16	1.49e-14	21
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	36/752	84/8135	4.64	2.59e-16	1.85e-14	84
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	17/752	19/8135	9.68	3.19e-16	2.15e-14	19
GO:0034502	GO:0034502	protein localization to chromosome	17/752	19/8135	9.68	3.19e-16	2.15e-14	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	17/752	19/8135	9.68	3.19e-16	2.15e-14	19
GO:2001251	GO:2001251	negative regulation of chromosome organization	26/752	45/8135	6.25	3.83e-16	2.54e-14	45
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	28/752	53/8135	5.72	6.61e-16	4.31e-14	53
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	18/752	22/8135	8.85	1.03e-15	6.60e-14	22
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	17/752	20/8135	9.20	1.94e-15	1.22e-13	20
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	25/752	44/8135	6.15	2.47e-15	1.51e-13	44
GO:0000725	GO:0000725	recombinational repair	25/752	44/8135	6.15	2.47e-15	1.51e-13	44
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	16/752	18/8135	9.62	3.15e-15	1.83e-13	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	16/752	18/8135	9.62	3.15e-15	1.83e-13	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	16/752	18/8135	9.62	3.15e-15	1.83e-13	18
GO:0032392	GO:0032392	DNA geometric change	18/752	23/8135	8.47	4.34e-15	2.48e-13	23
GO:0090068	GO:0090068	positive regulation of cell cycle process	41/752	116/8135	3.82	7.02e-15	3.96e-13	116
GO:0033044	GO:0033044	regulation of chromosome organization	37/752	97/8135	4.13	9.12e-15	5.07e-13	97
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	17/752	21/8135	8.76	9.32e-15	5.11e-13	21
GO:0045787	GO:0045787	positive regulation of cell cycle	50/752	166/8135	3.26	1.18e-14	6.38e-13	166
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	18/752	24/8135	8.11	1.59e-14	8.44e-13	24
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	25/752	47/8135	5.75	1.98e-14	1.04e-12	47
GO:1903046	GO:1903046	meiotic cell cycle process	39/752	112/8135	3.77	5.70e-14	2.95e-12	112
GO:0032508	GO:0032508	DNA duplex unwinding	16/752	20/8135	8.65	8.33e-14	4.26e-12	20
GO:0051784	GO:0051784	negative regulation of nuclear division	19/752	29/8135	7.09	1.49e-13	7.51e-12	29
GO:0006325	GO:0006325	chromatin organization	63/752	261/8135	2.61	3.79e-13	1.88e-11	261
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	13/752	14/8135	10.00	4.20e-13	2.06e-11	14
GO:0033043	GO:0033043	regulation of organelle organization	92/752	467/8135	2.13	6.01e-13	2.91e-11	467
GO:0051310	GO:0051310	metaphase plate congression	15/752	19/8135	8.54	7.35e-13	3.52e-11	19
GO:0140013	GO:0140013	meiotic nuclear division	36/752	107/8135	3.64	1.76e-12	8.32e-11	107
GO:0000910	GO:0000910	cytokinesis	25/752	55/8135	4.92	2.01e-12	9.37e-11	55
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:0031577	GO:0031577	spindle checkpoint	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:0071173	GO:0071173	spindle assembly checkpoint	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	13/752	15/8135	9.38	2.88e-12	1.25e-10	15
GO:0006323	GO:0006323	DNA packaging	34/752	100/8135	3.68	5.26e-12	2.26e-10	100
GO:0000226	GO:0000226	microtubule cytoskeleton organization	55/752	224/8135	2.66	6.17e-12	2.62e-10	224
GO:0007017	GO:0007017	microtubule-based process	66/752	298/8135	2.40	7.04e-12	2.96e-10	298
GO:0000077	GO:0000077	DNA damage checkpoint	20/752	38/8135	5.69	1.10e-11	4.57e-10	38
GO:0007080	GO:0007080	mitotic metaphase plate congression	12/752	14/8135	9.27	2.74e-11	1.13e-09	14
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/752	10/8135	10.80	4.31e-11	1.74e-09	10
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	11/752	12/8135	9.92	4.33e-11	1.74e-09	12
GO:0044774	GO:0044774	mitotic DNA integrity checkpoint	18/752	33/8135	5.90	5.47e-11	2.17e-09	33
GO:0010639	GO:0010639	negative regulation of organelle organization	40/752	143/8135	3.03	7.43e-11	2.93e-09	143
GO:0065004	GO:0065004	protein-DNA complex assembly	32/752	98/8135	3.53	7.54e-11	2.94e-09	98
GO:0071824	GO:0071824	protein-DNA complex subunit organization	34/752	109/8135	3.37	7.92e-11	3.06e-09	109
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	20/752	42/8135	5.15	1.18e-10	4.45e-09	42
GO:0034508	GO:0034508	centromere complex assembly	16/752	27/8135	6.41	1.20e-10	4.45e-09	27
GO:0050000	GO:0050000	chromosome localization	16/752	27/8135	6.41	1.20e-10	4.45e-09	27
GO:0051303	GO:0051303	establishment of chromosome localization	16/752	27/8135	6.41	1.20e-10	4.45e-09	27
GO:0006270	GO:0006270	DNA replication initiation	12/752	15/8135	8.65	1.26e-10	4.61e-09	15
GO:0000281	GO:0000281	mitotic cytokinesis	16/752	28/8135	6.18	2.57e-10	9.33e-09	28
GO:0051052	GO:0051052	regulation of DNA metabolic process	37/752	131/8135	3.06	2.86e-10	1.03e-08	131
GO:0072401	GO:0072401	signal transduction involved in DNA integrity checkpoint	14/752	22/8135	6.88	4.69e-10	1.66e-08	22
GO:0072422	GO:0072422	signal transduction involved in DNA damage checkpoint	14/752	22/8135	6.88	4.69e-10	1.66e-08	22
GO:0051225	GO:0051225	spindle assembly	16/752	29/8135	5.97	5.24e-10	1.83e-08	29
GO:0072395	GO:0072395	signal transduction involved in cell cycle checkpoint	14/752	23/8135	6.58	1.10e-09	3.79e-08	23
GO:0044786	GO:0044786	cell cycle DNA replication	11/752	14/8135	8.50	1.10e-09	3.79e-08	14
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	17/752	34/8135	5.41	1.14e-09	3.88e-08	34
GO:0090307	GO:0090307	mitotic spindle assembly	13/752	20/8135	7.03	1.37e-09	4.62e-08	20
GO:0007062	GO:0007062	sister chromatid cohesion	12/752	17/8135	7.64	1.43e-09	4.80e-08	17
GO:0042770	GO:0042770	signal transduction in response to DNA damage	19/752	43/8135	4.78	1.70e-09	5.64e-08	43
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	17/752	35/8135	5.25	2.03e-09	6.66e-08	35
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	14/752	24/8135	6.31	2.41e-09	7.79e-08	24
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	14/752	24/8135	6.31	2.41e-09	7.79e-08	24
GO:1902750	GO:1902750	negative regulation of cell cycle G2/M phase transition	13/752	21/8135	6.70	3.29e-09	1.05e-07	21
GO:0007098	GO:0007098	centrosome cycle	16/752	32/8135	5.41	3.55e-09	1.13e-07	32
GO:0031497	GO:0031497	chromatin assembly	27/752	85/8135	3.44	4.61e-09	1.45e-07	85
GO:0031055	GO:0031055	chromatin remodeling at centromere	14/752	25/8135	6.06	5.02e-09	1.57e-07	25
GO:0061982	GO:0061982	meiosis I cell cycle process	25/752	75/8135	3.61	5.66e-09	1.75e-07	75
GO:0006275	GO:0006275	regulation of DNA replication	16/752	33/8135	5.25	6.31e-09	1.94e-07	33
GO:0034728	GO:0034728	nucleosome organization	27/752	87/8135	3.36	8.13e-09	2.48e-07	87
GO:0072331	GO:0072331	signal transduction by p53 class mediator	24/752	71/8135	3.66	8.35e-09	2.52e-07	71
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	23/752	66/8135	3.77	8.78e-09	2.63e-07	66
GO:0006334	GO:0006334	nucleosome assembly	25/752	77/8135	3.51	1.04e-08	3.11e-07	77
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	13/752	23/8135	6.11	1.55e-08	4.55e-07	23
GO:0061641	GO:0061641	CENP-A containing chromatin organization	13/752	23/8135	6.11	1.55e-08	4.55e-07	23
GO:0045132	GO:0045132	meiotic chromosome segregation	20/752	53/8135	4.08	1.73e-08	5.03e-07	53
GO:0006333	GO:0006333	chromatin assembly or disassembly	27/752	90/8135	3.25	1.84e-08	5.30e-07	90
GO:0043486	GO:0043486	histone exchange	14/752	27/8135	5.61	1.89e-08	5.42e-07	27
GO:0043161	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	25/752	81/8135	3.34	3.30e-08	9.38e-07	81
GO:0006511	GO:0006511	ubiquitin-dependent protein catabolic process	32/752	123/8135	2.81	4.10e-08	1.16e-06	123
GO:0032200	GO:0032200	telomere organization	18/752	46/8135	4.23	4.66e-08	1.30e-06	46
GO:0031023	GO:0031023	microtubule organizing center organization	16/752	37/8135	4.68	4.88e-08	1.36e-06	37
GO:0019941	GO:0019941	modification-dependent protein catabolic process	32/752	124/8135	2.79	5.06e-08	1.39e-06	124
GO:0007127	GO:0007127	meiosis I	23/752	72/8135	3.46	5.73e-08	1.57e-06	72
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	14/752	29/8135	5.22	6.13e-08	1.66e-06	29
GO:0044773	GO:0044773	mitotic DNA damage checkpoint	14/752	29/8135	5.22	6.13e-08	1.66e-06	29
GO:0043632	GO:0043632	modification-dependent macromolecule catabolic process	32/752	125/8135	2.77	6.21e-08	1.66e-06	125
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	9/752	12/8135	8.11	8.02e-08	2.12e-06	12
GO:0033260	GO:0033260	nuclear DNA replication	9/752	12/8135	8.11	8.02e-08	2.12e-06	12
GO:0033365	GO:0033365	protein localization to organelle	45/752	216/8135	2.25	1.23e-07	3.22e-06	216
GO:0006338	GO:0006338	chromatin remodeling	20/752	59/8135	3.67	1.40e-07	3.64e-06	59
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	18/752	49/8135	3.97	1.46e-07	3.78e-06	49
GO:0032465	GO:0032465	regulation of cytokinesis	14/752	31/8135	4.89	1.76e-07	4.52e-06	31
GO:2000779	GO:2000779	regulation of double-strand break repair	12/752	23/8135	5.64	1.85e-07	4.73e-06	23
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	22/752	71/8135	3.35	2.04e-07	5.18e-06	71
GO:0010498	GO:0010498	proteasomal protein catabolic process	26/752	94/8135	2.99	2.07e-07	5.22e-06	94
GO:0030330	GO:0030330	DNA damage response, signal transduction by p53 class mediator	15/752	36/8135	4.51	2.34e-07	5.86e-06	36
GO:0006282	GO:0006282	regulation of DNA repair	15/752	37/8135	4.39	3.60e-07	8.96e-06	37
GO:0000079	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	16/752	42/8135	4.12	4.05e-07	1.00e-05	42
GO:0006890	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:0006977	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:0010569	GO:0010569	regulation of double-strand break repair via homologous recombination	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:0010972	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:0072413	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:0072431	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:1902400	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:1902402	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:1902403	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	10/752	17/8135	6.36	4.58e-07	1.07e-05	17
GO:2000045	GO:2000045	regulation of G1/S transition of mitotic cell cycle	17/752	48/8135	3.83	5.97e-07	1.38e-05	48
GO:0090329	GO:0090329	regulation of DNA-dependent DNA replication	9/752	14/8135	6.95	6.15e-07	1.42e-05	14
GO:0045738	GO:0045738	negative regulation of DNA repair	8/752	11/8135	7.87	6.59e-07	1.49e-05	11
GO:0070316	GO:0070316	regulation of G0 to G1 transition	8/752	11/8135	7.87	6.59e-07	1.49e-05	11
GO:2000780	GO:2000780	negative regulation of double-strand break repair	8/752	11/8135	7.87	6.59e-07	1.49e-05	11
GO:1902806	GO:1902806	regulation of cell cycle G1/S phase transition	18/752	54/8135	3.61	7.86e-07	1.76e-05	54
GO:0051603	GO:0051603	proteolysis involved in cellular protein catabolic process	34/752	152/8135	2.42	7.89e-07	1.76e-05	152
GO:0044257	GO:0044257	cellular protein catabolic process	36/752	166/8135	2.35	8.30e-07	1.85e-05	166
GO:0031571	GO:0031571	mitotic G1 DNA damage checkpoint	10/752	18/8135	6.01	9.45e-07	2.06e-05	18
GO:0044783	GO:0044783	G1 DNA damage checkpoint	10/752	18/8135	6.01	9.45e-07	2.06e-05	18
GO:0044819	GO:0044819	mitotic G1/S transition checkpoint	10/752	18/8135	6.01	9.45e-07	2.06e-05	18
GO:1904029	GO:1904029	regulation of cyclin-dependent protein kinase activity	16/752	45/8135	3.85	1.21e-06	2.62e-05	45
GO:0000723	GO:0000723	telomere maintenance	14/752	36/8135	4.21	1.62e-06	3.50e-05	36
GO:0071158	GO:0071158	positive regulation of cell cycle arrest	12/752	27/8135	4.81	1.68e-06	3.61e-05	27
GO:0071156	GO:0071156	regulation of cell cycle arrest	15/752	41/8135	3.96	1.72e-06	3.66e-05	41
GO:0031572	GO:0031572	G2 DNA damage checkpoint	8/752	12/8135	7.21	1.82e-06	3.82e-05	12
GO:0044818	GO:0044818	mitotic G2/M transition checkpoint	8/752	12/8135	7.21	1.82e-06	3.82e-05	12
GO:0045023	GO:0045023	G0 to G1 transition	8/752	12/8135	7.21	1.82e-06	3.82e-05	12
GO:0007050	GO:0007050	cell cycle arrest	25/752	99/8135	2.73	2.27e-06	4.74e-05	99
GO:2001020	GO:2001020	regulation of response to DNA damage stimulus	20/752	69/8135	3.14	2.37e-06	4.92e-05	69
GO:0051302	GO:0051302	regulation of cell division	23/752	87/8135	2.86	2.46e-06	5.09e-05	87
GO:0006342	GO:0006342	chromatin silencing	15/752	44/8135	3.69	4.77e-06	9.80e-05	44
GO:0034622	GO:0034622	cellular protein-containing complex assembly	61/752	372/8135	1.77	5.19e-06	1.06e-04	372
GO:0000726	GO:0000726	non-recombinational repair	11/752	25/8135	4.76	5.20e-06	1.06e-04	25
GO:0000729	GO:0000729	DNA double-strand break processing	7/752	10/8135	7.57	5.25e-06	1.06e-04	10
GO:0045740	GO:0045740	positive regulation of DNA replication	9/752	17/8135	5.73	5.78e-06	1.16e-04	17
GO:2001021	GO:2001021	negative regulation of response to DNA damage stimulus	11/752	26/8135	4.58	8.26e-06	1.65e-04	26
GO:0070647	GO:0070647	protein modification by small protein conjugation or removal	45/752	251/8135	1.94	9.34e-06	1.86e-04	251
GO:0000018	GO:0000018	regulation of DNA recombination	14/752	41/8135	3.69	9.70e-06	1.92e-04	41
GO:1902751	GO:1902751	positive regulation of cell cycle G2/M phase transition	9/752	18/8135	5.41	1.06e-05	2.09e-04	18
GO:0036297	GO:0036297	interstrand cross-link repair	7/752	11/8135	6.88	1.33e-05	2.60e-04	11
GO:2000134	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	12/752	32/8135	4.06	1.41e-05	2.75e-04	32
GO:0070507	GO:0070507	regulation of microtubule cytoskeleton organization	18/752	65/8135	3.00	1.52e-05	2.95e-04	65
GO:0006303	GO:0006303	double-strand break repair via nonhomologous end joining	10/752	23/8135	4.70	1.61e-05	3.10e-04	23
GO:0046605	GO:0046605	regulation of centrosome cycle	8/752	15/8135	5.77	1.83e-05	3.52e-04	15
GO:0007131	GO:0007131	reciprocal meiotic recombination	11/752	28/8135	4.25	1.93e-05	3.67e-04	28
GO:0035825	GO:0035825	homologous recombination	11/752	28/8135	4.25	1.93e-05	3.67e-04	28
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	22/752	92/8135	2.59	2.32e-05	4.39e-04	92
GO:0051640	GO:0051640	organelle localization	44/752	254/8135	1.87	2.85e-05	5.35e-04	254
GO:1902807	GO:1902807	negative regulation of cell cycle G1/S phase transition	12/752	34/8135	3.82	2.88e-05	5.39e-04	34
GO:0016579	GO:0016579	protein deubiquitination	16/752	56/8135	3.09	2.94e-05	5.45e-04	56
GO:0070646	GO:0070646	protein modification by small protein removal	16/752	56/8135	3.09	2.94e-05	5.45e-04	56
GO:0070925	GO:0070925	organelle assembly	47/752	279/8135	1.82	3.20e-05	5.90e-04	279
GO:0010971	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	8/752	16/8135	5.41	3.37e-05	6.19e-04	16
GO:0000209	GO:0000209	protein polyubiquitination	18/752	69/8135	2.82	3.69e-05	6.74e-04	69
GO:0051129	GO:0051129	negative regulation of cellular component organization	51/752	318/8135	1.73	5.73e-05	1.04e-03	318
GO:0051782	GO:0051782	negative regulation of cell division	7/752	13/8135	5.82	5.85e-05	1.05e-03	13
GO:0045910	GO:0045910	negative regulation of DNA recombination	8/752	17/8135	5.09	5.86e-05	1.05e-03	17
GO:0010638	GO:0010638	positive regulation of organelle organization	38/752	216/8135	1.90	7.06e-05	1.26e-03	216
GO:0030163	GO:0030163	protein catabolic process	41/752	242/8135	1.83	8.92e-05	1.59e-03	242
GO:0006284	GO:0006284	base-excision repair	6/752	10/8135	6.49	9.28e-05	1.64e-03	10
GO:0045005	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	6/752	10/8135	6.49	9.28e-05	1.64e-03	10
GO:0030261	GO:0030261	chromosome condensation	8/752	18/8135	4.81	9.69e-05	1.70e-03	18
GO:0048193	GO:0048193	Golgi vesicle transport	20/752	87/8135	2.49	9.81e-05	1.72e-03	87
GO:0044380	GO:0044380	protein localization to cytoskeleton	7/752	14/8135	5.41	1.08e-04	1.88e-03	14
GO:0016567	GO:0016567	protein ubiquitination	35/752	197/8135	1.92	1.10e-04	1.91e-03	197
GO:0071897	GO:0071897	DNA biosynthetic process	14/752	50/8135	3.03	1.17e-04	2.02e-03	50
GO:0032886	GO:0032886	regulation of microtubule-based process	19/752	82/8135	2.51	1.30e-04	2.24e-03	82
GO:0080135	GO:0080135	regulation of cellular response to stress	43/752	263/8135	1.77	1.40e-04	2.39e-03	263
GO:0044265	GO:0044265	cellular macromolecule catabolic process	40/752	240/8135	1.80	1.56e-04	2.66e-03	240
GO:0000022	GO:0000022	mitotic spindle elongation	6/752	11/8135	5.90	1.88e-04	3.18e-03	11
GO:0051231	GO:0051231	spindle elongation	6/752	11/8135	5.90	1.88e-04	3.18e-03	11
GO:1903320	GO:1903320	regulation of protein modification by small protein conjugation or removal	14/752	54/8135	2.80	2.86e-04	4.81e-03	54
GO:0032446	GO:0032446	protein modification by small protein conjugation	35/752	207/8135	1.83	3.00e-04	5.01e-03	207
GO:0007143	GO:0007143	female meiotic nuclear division	7/752	16/8135	4.73	3.04e-04	5.07e-03	16
GO:0010822	GO:0010822	positive regulation of mitochondrion organization	10/752	31/8135	3.49	3.14e-04	5.21e-03	31
GO:0072698	GO:0072698	protein localization to microtubule cytoskeleton	6/752	12/8135	5.41	3.47e-04	5.73e-03	12
GO:0007569	GO:0007569	cell aging	11/752	37/8135	3.22	3.54e-04	5.82e-03	37
GO:0031396	GO:0031396	regulation of protein ubiquitination	13/752	49/8135	2.87	3.67e-04	6.01e-03	49
GO:0051053	GO:0051053	negative regulation of DNA metabolic process	12/752	43/8135	3.02	3.70e-04	6.02e-03	43
GO:0051338	GO:0051338	regulation of transferase activity	64/752	457/8135	1.51	4.12e-04	6.68e-03	457
GO:0045143	GO:0045143	homologous chromosome segregation	11/752	38/8135	3.13	4.57e-04	7.39e-03	38
GO:0007018	GO:0007018	microtubule-based movement	23/752	119/8135	2.09	4.80e-04	7.72e-03	119
GO:0009057	GO:0009057	macromolecule catabolic process	52/752	356/8135	1.58	5.34e-04	8.55e-03	356
GO:0016569	GO:0016569	covalent chromatin modification	23/752	120/8135	2.07	5.43e-04	8.66e-03	120
GO:0051445	GO:0051445	regulation of meiotic cell cycle	10/752	33/8135	3.28	5.53e-04	8.78e-03	33
GO:1901796	GO:1901796	regulation of signal transduction by p53 class mediator	11/752	39/8135	3.05	5.85e-04	9.25e-03	39
GO:0051298	GO:0051298	centrosome duplication	6/752	13/8135	4.99	5.94e-04	9.32e-03	13
GO:0051438	GO:0051438	regulation of ubiquitin-protein transferase activity	6/752	13/8135	4.99	5.94e-04	9.32e-03	13
GO:0045840	GO:0045840	positive regulation of mitotic nuclear division	8/752	23/8135	3.76	7.15e-04	1.11e-02	23
GO:0016572	GO:0016572	histone phosphorylation	7/752	18/8135	4.21	7.18e-04	1.11e-02	18
GO:0032467	GO:0032467	positive regulation of cytokinesis	7/752	18/8135	4.21	7.18e-04	1.11e-02	18
GO:0097193	GO:0097193	intrinsic apoptotic signaling pathway	21/752	108/8135	2.10	7.67e-04	1.18e-02	108
GO:0060968	GO:0060968	regulation of gene silencing	13/752	53/8135	2.65	8.32e-04	1.28e-02	53
GO:0016458	GO:0016458	gene silencing	18/752	87/8135	2.24	8.41e-04	1.29e-02	87
GO:0006479	GO:0006479	protein methylation	11/752	41/8135	2.90	9.29e-04	1.41e-02	41
GO:0008213	GO:0008213	protein alkylation	11/752	41/8135	2.90	9.29e-04	1.41e-02	41
GO:0016570	GO:0016570	histone modification	22/752	117/8135	2.03	9.30e-04	1.41e-02	117
GO:0051307	GO:0051307	meiotic chromosome separation	6/752	14/8135	4.64	9.59e-04	1.43e-02	14
GO:0051653	GO:0051653	spindle localization	6/752	14/8135	4.64	9.59e-04	1.43e-02	14
GO:0061647	GO:0061647	histone H3-K9 modification	6/752	14/8135	4.64	9.59e-04	1.43e-02	14
GO:0051256	GO:0051256	mitotic spindle midzone assembly	5/752	10/8135	5.41	1.13e-03	1.68e-02	10
GO:0051567	GO:0051567	histone H3-K9 methylation	5/752	10/8135	5.41	1.13e-03	1.68e-02	10
GO:0051656	GO:0051656	establishment of organelle localization	33/752	206/8135	1.73	1.17e-03	1.72e-02	206
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	11/752	43/8135	2.77	1.43e-03	2.09e-02	43
GO:2001252	GO:2001252	positive regulation of chromosome organization	11/752	43/8135	2.77	1.43e-03	2.09e-02	43
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	10/752	37/8135	2.92	1.48e-03	2.16e-02	37
GO:0045739	GO:0045739	positive regulation of DNA repair	7/752	20/8135	3.79	1.48e-03	2.16e-02	20
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	11/752	44/8135	2.70	1.74e-03	2.52e-02	44
GO:0001824	GO:0001824	blastocyst development	8/752	26/8135	3.33	1.77e-03	2.55e-02	26
GO:0045185	GO:0045185	maintenance of protein location	10/752	38/8135	2.85	1.85e-03	2.64e-02	38
GO:0051651	GO:0051651	maintenance of location in cell	9/752	32/8135	3.04	1.87e-03	2.67e-02	32
GO:0031062	GO:0031062	positive regulation of histone methylation	5/752	11/8135	4.92	1.92e-03	2.69e-02	11
GO:0051255	GO:0051255	spindle midzone assembly	5/752	11/8135	4.92	1.92e-03	2.69e-02	11
GO:0090224	GO:0090224	regulation of spindle organization	5/752	11/8135	4.92	1.92e-03	2.69e-02	11
GO:0097711	GO:0097711	ciliary basal body-plasma membrane docking	5/752	11/8135	4.92	1.92e-03	2.69e-02	11
GO:0090398	GO:0090398	cellular senescence	7/752	21/8135	3.61	2.05e-03	2.87e-02	21
GO:0010821	GO:0010821	regulation of mitochondrion organization	11/752	45/8135	2.64	2.12e-03	2.96e-02	45
GO:0090342	GO:0090342	regulation of cell aging	6/752	16/8135	4.06	2.18e-03	3.02e-02	16
GO:0006027	GO:0006027	glycosaminoglycan catabolic process	10/752	40/8135	2.70	2.80e-03	3.86e-02	40
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	10/752	40/8135	2.70	2.80e-03	3.86e-02	40
GO:0008637	GO:0008637	apoptotic mitochondrial changes	9/752	34/8135	2.86	2.96e-03	4.04e-02	34
GO:0016571	GO:0016571	histone methylation	9/752	34/8135	2.86	2.96e-03	4.04e-02	34
GO:1903322	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	9/752	34/8135	2.86	2.96e-03	4.04e-02	34
GO:0051293	GO:0051293	establishment of spindle localization	5/752	12/8135	4.51	3.04e-03	4.13e-02	12
GO:0007005	GO:0007005	mitochondrion organization	18/752	98/8135	1.99	3.43e-03	4.64e-02	98
GO:2001022	GO:2001022	positive regulation of response to DNA damage stimulus	9/752	35/8135	2.78	3.67e-03	4.92e-02	35
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	7/752	23/8135	3.29	3.67e-03	4.92e-02	23
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	7/752	23/8135	3.29	3.67e-03	4.92e-02	23

Factor 14 : 736 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001944	GO:0001944	vasculature development	194/2060	417/8135	1.84	5.31e-22	1.76e-18	417
GO:0072358	GO:0072358	cardiovascular system development	194/2060	422/8135	1.82	2.99e-21	4.94e-18	422
GO:0001568	GO:0001568	blood vessel development	186/2060	401/8135	1.83	6.20e-21	6.84e-18	401
GO:0001525	GO:0001525	angiogenesis	150/2060	306/8135	1.94	8.00e-20	6.34e-17	306
GO:0048514	GO:0048514	blood vessel morphogenesis	169/2060	360/8135	1.85	9.57e-20	6.34e-17	360
GO:0035239	GO:0035239	tube morphogenesis	213/2060	499/8135	1.69	1.75e-18	9.65e-16	499
GO:0045765	GO:0045765	regulation of angiogenesis	92/2060	178/8135	2.04	2.38e-14	1.13e-11	178
GO:1901342	GO:1901342	regulation of vasculature development	100/2060	200/8135	1.97	2.82e-14	1.17e-11	200
GO:0030334	GO:0030334	regulation of cell migration	195/2060	490/8135	1.57	2.66e-13	9.79e-11	490
GO:0040017	GO:0040017	positive regulation of locomotion	138/2060	319/8135	1.71	8.26e-13	2.73e-10	319
GO:2000147	GO:2000147	positive regulation of cell motility	131/2060	302/8135	1.71	2.55e-12	7.68e-10	302
GO:0002040	GO:0002040	sprouting angiogenesis	43/2060	65/8135	2.61	4.23e-12	1.17e-09	65
GO:0030335	GO:0030335	positive regulation of cell migration	124/2060	287/8135	1.71	1.40e-11	3.56e-09	287
GO:0030155	GO:0030155	regulation of cell adhesion	166/2060	419/8135	1.56	2.81e-11	6.64e-09	419
GO:0051272	GO:0051272	positive regulation of cellular component movement	131/2060	311/8135	1.66	3.12e-11	6.87e-09	311
GO:0001935	GO:0001935	endothelial cell proliferation	48/2060	80/8135	2.37	4.47e-11	9.24e-09	80
GO:0010631	GO:0010631	epithelial cell migration	72/2060	142/8135	2.00	5.29e-11	1.03e-08	142
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	44/2060	71/8135	2.45	6.32e-11	1.16e-08	71
GO:0090132	GO:0090132	epithelium migration	72/2060	143/8135	1.99	8.06e-11	1.40e-08	143
GO:0043062	GO:0043062	extracellular structure organization	126/2060	300/8135	1.66	9.50e-11	1.51e-08	300
GO:0001667	GO:0001667	ameboidal-type cell migration	95/2060	208/8135	1.80	9.58e-11	1.51e-08	208
GO:0043542	GO:0043542	endothelial cell migration	55/2060	99/8135	2.19	1.15e-10	1.73e-08	99
GO:0032496	GO:0032496	response to lipopolysaccharide	96/2060	213/8135	1.78	1.89e-10	2.72e-08	213
GO:0002237	GO:0002237	response to molecule of bacterial origin	99/2060	222/8135	1.76	2.04e-10	2.81e-08	222
GO:0030198	GO:0030198	extracellular matrix organization	113/2060	264/8135	1.69	2.32e-10	3.07e-08	264
GO:1904018	GO:1904018	positive regulation of vasculature development	62/2060	119/8135	2.06	2.77e-10	3.52e-08	119
GO:0090130	GO:0090130	tissue migration	73/2060	149/8135	1.93	3.01e-10	3.69e-08	149
GO:0050727	GO:0050727	regulation of inflammatory response	108/2060	251/8135	1.70	4.06e-10	4.80e-08	251
GO:0043534	GO:0043534	blood vessel endothelial cell migration	34/2060	52/8135	2.58	1.23e-09	1.35e-07	52
GO:0051051	GO:0051051	negative regulation of transport	113/2060	271/8135	1.65	1.52e-09	1.54e-07	271
GO:0031347	GO:0031347	regulation of defense response	162/2060	425/8135	1.51	1.53e-09	1.54e-07	425
GO:0019216	GO:0019216	regulation of lipid metabolic process	89/2060	200/8135	1.76	1.94e-09	1.88e-07	200
GO:0060326	GO:0060326	cell chemotaxis	96/2060	221/8135	1.72	2.13e-09	1.94e-07	221
GO:0050673	GO:0050673	epithelial cell proliferation	99/2060	230/8135	1.70	2.16e-09	1.94e-07	230
GO:0019932	GO:0019932	second-messenger-mediated signaling	126/2060	314/8135	1.58	3.08e-09	2.68e-07	314
GO:0009617	GO:0009617	response to bacterium	152/2060	398/8135	1.51	4.34e-09	3.68e-07	398
GO:0050678	GO:0050678	regulation of epithelial cell proliferation	87/2060	197/8135	1.74	4.65e-09	3.84e-07	197
GO:0006897	GO:0006897	endocytosis	139/2060	357/8135	1.54	4.86e-09	3.92e-07	357
GO:0008285	GO:0008285	negative regulation of cell proliferation	150/2060	394/8135	1.50	7.07e-09	5.44e-07	394
GO:0019935	GO:0019935	cyclic-nucleotide-mediated signaling	73/2060	158/8135	1.82	7.92e-09	5.86e-07	158
GO:0001501	GO:0001501	skeletal system development	131/2060	334/8135	1.55	8.09e-09	5.86e-07	334
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	86/2060	196/8135	1.73	8.32e-09	5.86e-07	196
GO:0000302	GO:0000302	response to reactive oxygen species	52/2060	100/8135	2.05	8.33e-09	5.86e-07	100
GO:0071674	GO:0071674	mononuclear cell migration	39/2060	67/8135	2.30	1.00e-08	6.93e-07	67
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	93/2060	218/8135	1.68	1.15e-08	7.60e-07	218
GO:0010594	GO:0010594	regulation of endothelial cell migration	42/2060	75/8135	2.21	1.33e-08	8.55e-07	75
GO:0006898	GO:0006898	receptor-mediated endocytosis	79/2060	177/8135	1.76	1.34e-08	8.55e-07	177
GO:0045785	GO:0045785	positive regulation of cell adhesion	107/2060	262/8135	1.61	1.62e-08	1.01e-06	262
GO:0045766	GO:0045766	positive regulation of angiogenesis	54/2060	107/8135	1.99	1.69e-08	1.04e-06	107
GO:0033002	GO:0033002	muscle cell proliferation	60/2060	124/8135	1.91	2.09e-08	1.23e-06	124
GO:0022407	GO:0022407	regulation of cell-cell adhesion	106/2060	260/8135	1.61	2.11e-08	1.23e-06	260
GO:0048659	GO:0048659	smooth muscle cell proliferation	47/2060	89/8135	2.09	2.30e-08	1.31e-06	89
GO:0050679	GO:0050679	positive regulation of epithelial cell proliferation	59/2060	122/8135	1.91	2.80e-08	1.52e-06	122
GO:0050867	GO:0050867	positive regulation of cell activation	89/2060	210/8135	1.67	3.46e-08	1.82e-06	210
GO:0050900	GO:0050900	leukocyte migration	120/2060	306/8135	1.55	3.54e-08	1.83e-06	306
GO:0019933	GO:0019933	cAMP-mediated signaling	64/2060	137/8135	1.84	3.93e-08	2.00e-06	137
GO:0002042	GO:0002042	cell migration involved in sprouting angiogenesis	22/2060	30/8135	2.90	4.52e-08	2.27e-06	30
GO:0048660	GO:0048660	regulation of smooth muscle cell proliferation	46/2060	88/8135	2.06	4.89e-08	2.42e-06	88
GO:1901652	GO:1901652	response to peptide	100/2060	245/8135	1.61	4.98e-08	2.43e-06	245
GO:0001819	GO:0001819	positive regulation of cytokine production	108/2060	271/8135	1.57	6.51e-08	3.08e-06	271
GO:0097529	GO:0097529	myeloid leukocyte migration	69/2060	154/8135	1.77	9.25e-08	4.31e-06	154
GO:0010632	GO:0010632	regulation of epithelial cell migration	53/2060	109/8135	1.92	1.13e-07	5.20e-06	109
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	95/2060	233/8135	1.61	1.15e-07	5.20e-06	233
GO:0002548	GO:0002548	monocyte chemotaxis	32/2060	54/8135	2.34	1.19e-07	5.29e-06	54
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	67/2060	149/8135	1.78	1.20e-07	5.29e-06	149
GO:0006874	GO:0006874	cellular calcium ion homeostasis	120/2060	312/8135	1.52	1.26e-07	5.40e-06	312
GO:0030595	GO:0030595	leukocyte chemotaxis	74/2060	170/8135	1.72	1.36e-07	5.78e-06	170
GO:0051216	GO:0051216	cartilage development	66/2060	148/8135	1.76	2.18e-07	9.02e-06	148
GO:0032103	GO:0032103	positive regulation of response to external stimulus	86/2060	208/8135	1.63	2.22e-07	9.07e-06	208
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	104/2060	264/8135	1.56	2.26e-07	9.12e-06	264
GO:0062012	GO:0062012	regulation of small molecule metabolic process	76/2060	178/8135	1.69	2.42e-07	9.63e-06	178
GO:0016525	GO:0016525	negative regulation of angiogenesis	35/2060	63/8135	2.19	2.82e-07	1.09e-05	63
GO:0006979	GO:0006979	response to oxidative stress	80/2060	191/8135	1.65	3.09e-07	1.18e-05	191
GO:0061448	GO:0061448	connective tissue development	76/2060	179/8135	1.68	3.18e-07	1.18e-05	179
GO:0010565	GO:0010565	regulation of cellular ketone metabolic process	38/2060	71/8135	2.11	3.22e-07	1.19e-05	71
GO:0007162	GO:0007162	negative regulation of cell adhesion	70/2060	162/8135	1.71	4.17e-07	1.50e-05	162
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	75/2060	177/8135	1.67	4.18e-07	1.50e-05	177
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	24/2060	37/8135	2.56	4.37e-07	1.55e-05	37
GO:0002696	GO:0002696	positive regulation of leukocyte activation	83/2060	202/8135	1.62	4.94e-07	1.74e-05	202
GO:0043434	GO:0043434	response to peptide hormone	86/2060	212/8135	1.60	5.93e-07	2.07e-05	212
GO:0002250	GO:0002250	adaptive immune response	104/2060	269/8135	1.53	6.59e-07	2.22e-05	269
GO:0002062	GO:0002062	chondrocyte differentiation	43/2060	86/8135	1.97	6.71e-07	2.24e-05	86
GO:0050729	GO:0050729	positive regulation of inflammatory response	48/2060	100/8135	1.90	7.24e-07	2.40e-05	100
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	35/2060	65/8135	2.13	7.75e-07	2.54e-05	65
GO:0045444	GO:0045444	fat cell differentiation	57/2060	126/8135	1.79	8.18e-07	2.65e-05	126
GO:0070371	GO:0070371	ERK1 and ERK2 cascade	91/2060	229/8135	1.57	8.28e-07	2.66e-05	229
GO:0002685	GO:0002685	regulation of leukocyte migration	59/2060	132/8135	1.77	8.66e-07	2.76e-05	132
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	24/2060	38/8135	2.49	9.02e-07	2.84e-05	38
GO:0071346	GO:0071346	cellular response to interferon-gamma	52/2060	112/8135	1.83	9.29e-07	2.90e-05	112
GO:0042180	GO:0042180	cellular ketone metabolic process	48/2060	101/8135	1.88	1.04e-06	3.23e-05	101
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	30/2060	53/8135	2.24	1.17e-06	3.58e-05	53
GO:0050870	GO:0050870	positive regulation of T cell activation	61/2060	139/8135	1.73	1.22e-06	3.70e-05	139
GO:0046677	GO:0046677	response to antibiotic	69/2060	163/8135	1.67	1.26e-06	3.76e-05	163
GO:0072001	GO:0072001	renal system development	79/2060	194/8135	1.61	1.42e-06	4.08e-05	194
GO:0001937	GO:0001937	negative regulation of endothelial cell proliferation	15/2060	19/8135	3.12	1.44e-06	4.08e-05	19
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	71/2060	170/8135	1.65	1.62e-06	4.53e-05	170
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	40/2060	80/8135	1.97	1.64e-06	4.56e-05	80
GO:0007517	GO:0007517	muscle organ development	97/2060	252/8135	1.52	1.97e-06	5.44e-05	252
GO:0007189	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	48/2060	103/8135	1.84	2.12e-06	5.80e-05	103
GO:0070555	GO:0070555	response to interleukin-1	43/2060	89/8135	1.91	2.18e-06	5.93e-05	89
GO:0030323	GO:0030323	respiratory tube development	51/2060	112/8135	1.80	2.42e-06	6.41e-05	112
GO:0051249	GO:0051249	regulation of lymphocyte activation	99/2060	260/8135	1.50	2.72e-06	7.02e-05	260
GO:0050863	GO:0050863	regulation of T cell activation	81/2060	203/8135	1.58	2.74e-06	7.02e-05	203
GO:0007187	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	80/2060	200/8135	1.58	2.81e-06	7.16e-05	200
GO:1990845	GO:1990845	adaptive thermogenesis	42/2060	87/8135	1.91	2.94e-06	7.42e-05	87
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	38/2060	76/8135	1.97	2.97e-06	7.45e-05	76
GO:0001822	GO:0001822	kidney development	74/2060	182/8135	1.61	3.26e-06	8.11e-05	182
GO:0014068	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	26/2060	45/8135	2.28	3.59e-06	8.86e-05	45
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	47/2060	102/8135	1.82	3.99e-06	9.78e-05	102
GO:0031294	GO:0031294	lymphocyte costimulation	23/2060	38/8135	2.39	4.41e-06	1.07e-04	38
GO:0070374	GO:0070374	positive regulation of ERK1 and ERK2 cascade	71/2060	174/8135	1.61	4.42e-06	1.07e-04	174
GO:0030324	GO:0030324	lung development	50/2060	111/8135	1.78	4.45e-06	1.07e-04	111
GO:0046320	GO:0046320	regulation of fatty acid oxidation	14/2060	18/8135	3.07	4.53e-06	1.08e-04	18
GO:0009612	GO:0009612	response to mechanical stimulus	57/2060	132/8135	1.71	5.00e-06	1.17e-04	132
GO:0007188	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	71/2060	175/8135	1.60	5.62e-06	1.29e-04	175
GO:1990868	GO:1990868	response to chemokine	41/2060	86/8135	1.88	5.72e-06	1.29e-04	86
GO:1990869	GO:1990869	cellular response to chemokine	41/2060	86/8135	1.88	5.72e-06	1.29e-04	86
GO:0001655	GO:0001655	urogenital system development	85/2060	219/8135	1.53	5.78e-06	1.29e-04	219
GO:0070372	GO:0070372	regulation of ERK1 and ERK2 cascade	85/2060	219/8135	1.53	5.78e-06	1.29e-04	219
GO:0019217	GO:0019217	regulation of fatty acid metabolic process	26/2060	46/8135	2.23	6.27e-06	1.39e-04	46
GO:0046890	GO:0046890	regulation of lipid biosynthetic process	43/2060	92/8135	1.85	6.48e-06	1.43e-04	92
GO:0050663	GO:0050663	cytokine secretion	61/2060	145/8135	1.66	6.55e-06	1.43e-04	145
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	44/2060	95/8135	1.83	6.82e-06	1.48e-04	95
GO:0001659	GO:0001659	temperature homeostasis	46/2060	101/8135	1.80	7.42e-06	1.59e-04	101
GO:0034614	GO:0034614	cellular response to reactive oxygen species	32/2060	62/8135	2.04	7.59e-06	1.61e-04	62
GO:0050920	GO:0050920	regulation of chemotaxis	61/2060	146/8135	1.65	8.51e-06	1.77e-04	146
GO:1903672	GO:1903672	positive regulation of sprouting angiogenesis	17/2060	25/8135	2.69	8.57e-06	1.77e-04	25
GO:0002699	GO:0002699	positive regulation of immune effector process	59/2060	140/8135	1.66	8.66e-06	1.77e-04	140
GO:0060541	GO:0060541	respiratory system development	55/2060	128/8135	1.70	8.72e-06	1.77e-04	128
GO:0071347	GO:0071347	cellular response to interleukin-1	37/2060	76/8135	1.92	8.85e-06	1.79e-04	76
GO:0036293	GO:0036293	response to decreased oxygen levels	69/2060	171/8135	1.59	9.47e-06	1.89e-04	171
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	28/2060	52/8135	2.13	9.84e-06	1.95e-04	52
GO:0046460	GO:0046460	neutral lipid biosynthetic process	16/2060	23/8135	2.75	1.02e-05	1.99e-04	23
GO:0046463	GO:0046463	acylglycerol biosynthetic process	16/2060	23/8135	2.75	1.02e-05	1.99e-04	23
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	39/2060	82/8135	1.88	1.03e-05	2.01e-04	82
GO:0002819	GO:0002819	regulation of adaptive immune response	47/2060	105/8135	1.77	1.05e-05	2.04e-04	105
GO:0031295	GO:0031295	T cell costimulation	22/2060	37/8135	2.35	1.07e-05	2.06e-04	37
GO:0034612	GO:0034612	response to tumor necrosis factor	62/2060	150/8135	1.63	1.09e-05	2.07e-04	150
GO:2001057	GO:2001057	reactive nitrogen species metabolic process	24/2060	42/8135	2.26	1.11e-05	2.09e-04	42
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	59/2060	141/8135	1.65	1.13e-05	2.12e-04	141
GO:0034341	GO:0034341	response to interferon-gamma	54/2060	126/8135	1.69	1.15e-05	2.15e-04	126
GO:0019432	GO:0019432	triglyceride biosynthetic process	15/2060	21/8135	2.82	1.18e-05	2.19e-04	21
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	33/2060	66/8135	1.97	1.32e-05	2.44e-04	66
GO:0042542	GO:0042542	response to hydrogen peroxide	30/2060	58/8135	2.04	1.38e-05	2.50e-04	58
GO:0048662	GO:0048662	negative regulation of smooth muscle cell proliferation	21/2060	35/8135	2.37	1.40e-05	2.52e-04	35
GO:0051048	GO:0051048	negative regulation of secretion	60/2060	145/8135	1.63	1.44e-05	2.58e-04	145
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	34/2060	69/8135	1.95	1.46e-05	2.61e-04	69
GO:0062013	GO:0062013	positive regulation of small molecule metabolic process	40/2060	86/8135	1.84	1.56e-05	2.76e-04	86
GO:0001101	GO:0001101	response to acid chemical	78/2060	202/8135	1.52	1.73e-05	2.99e-04	202
GO:0070482	GO:0070482	response to oxygen levels	71/2060	180/8135	1.56	1.78e-05	3.06e-04	180
GO:0072593	GO:0072593	reactive oxygen species metabolic process	59/2060	143/8135	1.63	1.88e-05	3.21e-04	143
GO:0001666	GO:0001666	response to hypoxia	67/2060	168/8135	1.57	2.00e-05	3.36e-04	168
GO:0001818	GO:0001818	negative regulation of cytokine production	66/2060	165/8135	1.58	2.06e-05	3.44e-04	165
GO:0003158	GO:0003158	endothelium development	30/2060	59/8135	2.01	2.13e-05	3.52e-04	59
GO:0045834	GO:0045834	positive regulation of lipid metabolic process	40/2060	87/8135	1.82	2.19e-05	3.61e-04	87
GO:1901343	GO:1901343	negative regulation of vasculature development	35/2060	73/8135	1.89	2.34e-05	3.82e-04	73
GO:0042102	GO:0042102	positive regulation of T cell proliferation	36/2060	76/8135	1.87	2.51e-05	4.05e-04	76
GO:0071229	GO:0071229	cellular response to acid chemical	55/2060	132/8135	1.65	2.56e-05	4.11e-04	132
GO:0042129	GO:0042129	regulation of T cell proliferation	47/2060	108/8135	1.72	2.60e-05	4.12e-04	108
GO:1903531	GO:1903531	negative regulation of secretion by cell	52/2060	123/8135	1.67	2.62e-05	4.12e-04	123
GO:0034599	GO:0034599	cellular response to oxidative stress	49/2060	114/8135	1.70	2.63e-05	4.12e-04	114
GO:0003018	GO:0003018	vascular process in circulatory system	50/2060	117/8135	1.69	2.64e-05	4.12e-04	117
GO:0106106	GO:0106106	cold-induced thermogenesis	38/2060	82/8135	1.83	2.81e-05	4.32e-04	82
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	38/2060	82/8135	1.83	2.81e-05	4.32e-04	82
GO:0051224	GO:0051224	negative regulation of protein transport	42/2060	94/8135	1.76	3.23e-05	4.95e-04	94
GO:0016051	GO:0016051	carbohydrate biosynthetic process	44/2060	100/8135	1.74	3.36e-05	5.11e-04	100
GO:0090049	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	14/2060	20/8135	2.76	3.37e-05	5.11e-04	20
GO:0071621	GO:0071621	granulocyte chemotaxis	45/2060	103/8135	1.73	3.41e-05	5.15e-04	103
GO:0097530	GO:0097530	granulocyte migration	48/2060	112/8135	1.69	3.48e-05	5.23e-04	112
GO:0070663	GO:0070663	regulation of leukocyte proliferation	63/2060	158/8135	1.57	3.53e-05	5.29e-04	158
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	31/2060	63/8135	1.94	3.59e-05	5.33e-04	63
GO:0030258	GO:0030258	lipid modification	61/2060	152/8135	1.58	3.72e-05	5.50e-04	152
GO:0032642	GO:0032642	regulation of chemokine production	28/2060	55/8135	2.01	3.88e-05	5.69e-04	55
GO:0002021	GO:0002021	response to dietary excess	13/2060	18/8135	2.85	3.88e-05	5.69e-04	18
GO:0032768	GO:0032768	regulation of monooxygenase activity	17/2060	27/8135	2.49	3.90e-05	5.69e-04	27
GO:0002821	GO:0002821	positive regulation of adaptive immune response	33/2060	69/8135	1.89	4.24e-05	6.07e-04	69
GO:0060191	GO:0060191	regulation of lipase activity	33/2060	69/8135	1.89	4.24e-05	6.07e-04	69
GO:1904950	GO:1904950	negative regulation of establishment of protein localization	42/2060	95/8135	1.75	4.40e-05	6.27e-04	95
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	19/2060	32/8135	2.34	4.44e-05	6.30e-04	32
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	43/2060	98/8135	1.73	4.47e-05	6.32e-04	98
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	60/2060	150/8135	1.58	4.82e-05	6.76e-04	150
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	37/2060	81/8135	1.80	5.25e-05	7.25e-04	81
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	37/2060	81/8135	1.80	5.25e-05	7.25e-04	81
GO:0002687	GO:0002687	positive regulation of leukocyte migration	39/2060	87/8135	1.77	5.60e-05	7.69e-04	87
GO:0051591	GO:0051591	response to cAMP	32/2060	67/8135	1.89	5.71e-05	7.75e-04	67
GO:0030593	GO:0030593	neutrophil chemotaxis	40/2060	90/8135	1.76	5.73e-05	7.75e-04	90
GO:0034440	GO:0034440	lipid oxidation	22/2060	40/8135	2.17	5.74e-05	7.75e-04	40
GO:0046209	GO:0046209	nitric oxide metabolic process	22/2060	40/8135	2.17	5.74e-05	7.75e-04	40
GO:0010863	GO:0010863	positive regulation of phospholipase C activity	20/2060	35/8135	2.26	6.01e-05	8.07e-04	35
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	44/2060	102/8135	1.70	6.03e-05	8.07e-04	102
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	60/2060	151/8135	1.57	6.06e-05	8.08e-04	151
GO:0060419	GO:0060419	heart growth	29/2060	59/8135	1.94	6.53e-05	8.61e-04	59
GO:0070542	GO:0070542	response to fatty acid	29/2060	59/8135	1.94	6.53e-05	8.61e-04	59
GO:0001570	GO:0001570	vasculogenesis	23/2060	43/8135	2.11	7.01e-05	9.17e-04	43
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	38/2060	85/8135	1.77	7.47e-05	9.73e-04	85
GO:0002367	GO:0002367	cytokine production involved in immune response	31/2060	65/8135	1.88	7.68e-05	9.90e-04	65
GO:0006809	GO:0006809	nitric oxide biosynthetic process	21/2060	38/8135	2.18	7.70e-05	9.90e-04	38
GO:0019915	GO:0019915	lipid storage	21/2060	38/8135	2.18	7.70e-05	9.90e-04	38
GO:0010596	GO:0010596	negative regulation of endothelial cell migration	14/2060	21/8135	2.63	7.75e-05	9.90e-04	21
GO:0048008	GO:0048008	platelet-derived growth factor receptor signaling pathway	14/2060	21/8135	2.63	7.75e-05	9.90e-04	21
GO:0097237	GO:0097237	cellular response to toxic substance	48/2060	115/8135	1.65	7.80e-05	9.93e-04	115
GO:0010517	GO:0010517	regulation of phospholipase activity	27/2060	54/8135	1.97	7.96e-05	1.00e-03	54
GO:1904659	GO:1904659	glucose transmembrane transport	27/2060	54/8135	1.97	7.96e-05	1.00e-03	54
GO:1901215	GO:1901215	negative regulation of neuron death	45/2060	106/8135	1.68	7.96e-05	1.00e-03	106
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	44/2060	103/8135	1.69	7.98e-05	1.00e-03	103
GO:0006091	GO:0006091	generation of precursor metabolites and energy	64/2060	165/8135	1.53	8.22e-05	1.03e-03	165
GO:0001701	GO:0001701	in utero embryonic development	56/2060	140/8135	1.58	8.51e-05	1.05e-03	140
GO:0097305	GO:0097305	response to alcohol	56/2060	140/8135	1.58	8.51e-05	1.05e-03	140
GO:0008217	GO:0008217	regulation of blood pressure	53/2060	131/8135	1.60	9.17e-05	1.13e-03	131
GO:0003014	GO:0003014	renal system process	35/2060	77/8135	1.80	9.40e-05	1.15e-03	77
GO:0006112	GO:0006112	energy reserve metabolic process	22/2060	41/8135	2.12	9.45e-05	1.15e-03	41
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	51/2060	125/8135	1.61	9.58e-05	1.17e-03	125
GO:0032602	GO:0032602	chemokine production	29/2060	60/8135	1.91	9.61e-05	1.17e-03	60
GO:0007202	GO:0007202	activation of phospholipase C activity	16/2060	26/8135	2.43	9.87e-05	1.19e-03	26
GO:0002792	GO:0002792	negative regulation of peptide secretion	37/2060	83/8135	1.76	9.96e-05	1.20e-03	83
GO:0043491	GO:0043491	protein kinase B signaling	58/2060	147/8135	1.56	1.01e-04	1.21e-03	147
GO:0043112	GO:0043112	receptor metabolic process	38/2060	86/8135	1.74	1.02e-04	1.21e-03	86
GO:1900274	GO:1900274	regulation of phospholipase C activity	20/2060	36/8135	2.19	1.03e-04	1.23e-03	36
GO:0050921	GO:0050921	positive regulation of chemotaxis	40/2060	92/8135	1.72	1.04e-04	1.24e-03	92
GO:0048015	GO:0048015	phosphatidylinositol-mediated signaling	42/2060	98/8135	1.69	1.05e-04	1.24e-03	98
GO:0045428	GO:0045428	regulation of nitric oxide biosynthetic process	18/2060	31/8135	2.29	1.06e-04	1.24e-03	31
GO:0045446	GO:0045446	endothelial cell differentiation	26/2060	52/8135	1.97	1.08e-04	1.26e-03	52
GO:0002573	GO:0002573	myeloid leukocyte differentiation	52/2060	129/8135	1.59	1.19e-04	1.38e-03	129
GO:0050707	GO:0050707	regulation of cytokine secretion	52/2060	129/8135	1.59	1.19e-04	1.38e-03	129
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	34/2060	75/8135	1.79	1.26e-04	1.45e-03	75
GO:0042098	GO:0042098	T cell proliferation	49/2060	120/8135	1.61	1.27e-04	1.46e-03	120
GO:0007190	GO:0007190	activation of adenylate cyclase activity	15/2060	24/8135	2.47	1.28e-04	1.46e-03	24
GO:0034694	GO:0034694	response to prostaglandin	15/2060	24/8135	2.47	1.28e-04	1.46e-03	24
GO:0031348	GO:0031348	negative regulation of defense response	48/2060	117/8135	1.62	1.30e-04	1.47e-03	117
GO:0008645	GO:0008645	hexose transmembrane transport	28/2060	58/8135	1.91	1.30e-04	1.47e-03	58
GO:1905476	GO:1905476	negative regulation of protein localization to membrane	9/2060	11/8135	3.23	1.39e-04	1.55e-03	11
GO:1990266	GO:1990266	neutrophil migration	41/2060	96/8135	1.69	1.39e-04	1.55e-03	96
GO:0120162	GO:0120162	positive regulation of cold-induced thermogenesis	29/2060	61/8135	1.88	1.39e-04	1.55e-03	61
GO:0051580	GO:0051580	regulation of neurotransmitter uptake	10/2060	13/8135	3.04	1.40e-04	1.55e-03	13
GO:0030336	GO:0030336	negative regulation of cell migration	59/2060	152/8135	1.53	1.50e-04	1.65e-03	152
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	52/2060	130/8135	1.58	1.50e-04	1.65e-03	130
GO:0002440	GO:0002440	production of molecular mediator of immune response	47/2060	115/8135	1.61	1.69e-04	1.83e-03	115
GO:0045598	GO:0045598	regulation of fat cell differentiation	34/2060	76/8135	1.77	1.73e-04	1.86e-03	76
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	44/2060	106/8135	1.64	1.78e-04	1.91e-03	106
GO:0048017	GO:0048017	inositol lipid-mediated signaling	42/2060	100/8135	1.66	1.81e-04	1.94e-03	100
GO:0009896	GO:0009896	positive regulation of catabolic process	53/2060	134/8135	1.56	1.83e-04	1.96e-03	134
GO:0071675	GO:0071675	regulation of mononuclear cell migration	18/2060	32/8135	2.22	1.85e-04	1.97e-03	32
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	16/2060	27/8135	2.34	1.86e-04	1.97e-03	27
GO:0015749	GO:0015749	monosaccharide transmembrane transport	28/2060	59/8135	1.87	1.88e-04	1.98e-03	59
GO:0031623	GO:0031623	receptor internalization	29/2060	62/8135	1.85	1.99e-04	2.09e-03	62
GO:0050886	GO:0050886	endocrine process	30/2060	65/8135	1.82	2.09e-04	2.17e-03	65
GO:0071216	GO:0071216	cellular response to biotic stimulus	53/2060	135/8135	1.55	2.29e-04	2.35e-03	135
GO:0019882	GO:0019882	antigen processing and presentation	36/2060	83/8135	1.71	2.41e-04	2.45e-03	83
GO:2000377	GO:2000377	regulation of reactive oxygen species metabolic process	37/2060	86/8135	1.70	2.42e-04	2.46e-03	86
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	15/2060	25/8135	2.37	2.44e-04	2.47e-03	25
GO:0072677	GO:0072677	eosinophil migration	15/2060	25/8135	2.37	2.44e-04	2.47e-03	25
GO:0061035	GO:0061035	regulation of cartilage development	23/2060	46/8135	1.97	2.66e-04	2.67e-03	46
GO:0034219	GO:0034219	carbohydrate transmembrane transport	28/2060	60/8135	1.84	2.68e-04	2.68e-03	60
GO:0019395	GO:0019395	fatty acid oxidation	20/2060	38/8135	2.08	2.77e-04	2.76e-03	38
GO:0008016	GO:0008016	regulation of heart contraction	59/2060	155/8135	1.50	2.78e-04	2.76e-03	155
GO:0031343	GO:0031343	positive regulation of cell killing	24/2060	49/8135	1.93	2.94e-04	2.85e-03	49
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	52/2060	133/8135	1.54	2.94e-04	2.85e-03	133
GO:0051896	GO:0051896	regulation of protein kinase B signaling	52/2060	133/8135	1.54	2.94e-04	2.85e-03	133
GO:0035150	GO:0035150	regulation of tube size	43/2060	105/8135	1.62	2.99e-04	2.87e-03	105
GO:0072006	GO:0072006	nephron development	43/2060	105/8135	1.62	2.99e-04	2.87e-03	105
GO:0008643	GO:0008643	carbohydrate transport	32/2060	72/8135	1.76	3.08e-04	2.95e-03	72
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	33/2060	75/8135	1.74	3.13e-04	2.95e-03	75
GO:0046631	GO:0046631	alpha-beta T cell activation	39/2060	93/8135	1.66	3.16e-04	2.95e-03	93
GO:0046683	GO:0046683	response to organophosphorus	39/2060	93/8135	1.66	3.16e-04	2.95e-03	93
GO:0001945	GO:0001945	lymph vessel development	11/2060	16/8135	2.71	3.18e-04	2.95e-03	16
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	11/2060	16/8135	2.71	3.18e-04	2.95e-03	16
GO:0071470	GO:0071470	cellular response to osmotic stress	11/2060	16/8135	2.71	3.18e-04	2.95e-03	16
GO:0055017	GO:0055017	cardiac muscle tissue growth	25/2060	52/8135	1.90	3.19e-04	2.95e-03	52
GO:0050728	GO:0050728	negative regulation of inflammatory response	37/2060	87/8135	1.68	3.20e-04	2.95e-03	87
GO:1902930	GO:1902930	regulation of alcohol biosynthetic process	21/2060	41/8135	2.02	3.20e-04	2.95e-03	41
GO:0015837	GO:0015837	amine transport	36/2060	84/8135	1.69	3.20e-04	2.95e-03	84
GO:0045429	GO:0045429	positive regulation of nitric oxide biosynthetic process	14/2060	23/8135	2.40	3.21e-04	2.95e-03	23
GO:0045923	GO:0045923	positive regulation of fatty acid metabolic process	14/2060	23/8135	2.40	3.21e-04	2.95e-03	23
GO:1904407	GO:1904407	positive regulation of nitric oxide metabolic process	14/2060	23/8135	2.40	3.21e-04	2.95e-03	23
GO:0008206	GO:0008206	bile acid metabolic process	16/2060	28/8135	2.26	3.32e-04	3.02e-03	28
GO:0048661	GO:0048661	positive regulation of smooth muscle cell proliferation	26/2060	55/8135	1.87	3.41e-04	3.09e-03	55
GO:0032835	GO:0032835	glomerulus development	22/2060	44/8135	1.97	3.61e-04	3.26e-03	44
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	57/2060	150/8135	1.50	3.68e-04	3.32e-03	150
GO:0090050	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	10/2060	14/8135	2.82	3.78e-04	3.40e-03	14
GO:0006694	GO:0006694	steroid biosynthetic process	43/2060	106/8135	1.60	3.81e-04	3.42e-03	106
GO:0045926	GO:0045926	negative regulation of growth	56/2060	147/8135	1.50	3.84e-04	3.43e-03	147
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	29/2060	64/8135	1.79	3.91e-04	3.49e-03	64
GO:0002709	GO:0002709	regulation of T cell mediated immunity	23/2060	47/8135	1.93	3.98e-04	3.53e-03	47
GO:0048245	GO:0048245	eosinophil chemotaxis	13/2060	21/8135	2.44	4.18e-04	3.66e-03	21
GO:0032609	GO:0032609	interferon-gamma production	37/2060	88/8135	1.66	4.19e-04	3.66e-03	88
GO:0001504	GO:0001504	neurotransmitter uptake	17/2060	31/8135	2.17	4.20e-04	3.66e-03	31
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	17/2060	31/8135	2.17	4.20e-04	3.66e-03	31
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	33/2060	76/8135	1.71	4.21e-04	3.66e-03	76
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	9/2060	12/8135	2.96	4.30e-04	3.69e-03	12
GO:0043537	GO:0043537	negative regulation of blood vessel endothelial cell migration	9/2060	12/8135	2.96	4.30e-04	3.69e-03	12
GO:0046321	GO:0046321	positive regulation of fatty acid oxidation	9/2060	12/8135	2.96	4.30e-04	3.69e-03	12
GO:0060193	GO:0060193	positive regulation of lipase activity	24/2060	50/8135	1.90	4.31e-04	3.69e-03	50
GO:0035265	GO:0035265	organ growth	47/2060	119/8135	1.56	4.32e-04	3.69e-03	119
GO:0010611	GO:0010611	regulation of cardiac muscle hypertrophy	15/2060	26/8135	2.28	4.43e-04	3.77e-03	26
GO:0034329	GO:0034329	cell junction assembly	46/2060	116/8135	1.57	4.45e-04	3.78e-03	116
GO:0031998	GO:0031998	regulation of fatty acid beta-oxidation	8/2060	10/8135	3.16	4.53e-04	3.82e-03	10
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	45/2060	113/8135	1.57	4.58e-04	3.85e-03	113
GO:0031331	GO:0031331	positive regulation of cellular catabolic process	44/2060	110/8135	1.58	4.71e-04	3.95e-03	110
GO:1903409	GO:1903409	reactive oxygen species biosynthetic process	26/2060	56/8135	1.83	4.85e-04	4.04e-03	56
GO:0097755	GO:0097755	positive regulation of blood vessel diameter	21/2060	42/8135	1.97	4.89e-04	4.04e-03	42
GO:0050880	GO:0050880	regulation of blood vessel size	42/2060	104/8135	1.59	4.96e-04	4.08e-03	104
GO:0060401	GO:0060401	cytosolic calcium ion transport	42/2060	104/8135	1.59	4.96e-04	4.08e-03	104
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	27/2060	59/8135	1.81	5.07e-04	4.16e-03	59
GO:0050866	GO:0050866	negative regulation of cell activation	48/2060	123/8135	1.54	5.20e-04	4.26e-03	123
GO:2001023	GO:2001023	regulation of response to drug	28/2060	62/8135	1.78	5.24e-04	4.28e-03	62
GO:0010518	GO:0010518	positive regulation of phospholipase activity	22/2060	45/8135	1.93	5.39e-04	4.37e-03	45
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	12/2060	19/8135	2.49	5.42e-04	4.37e-03	19
GO:0051147	GO:0051147	regulation of muscle cell differentiation	37/2060	89/8135	1.64	5.45e-04	4.39e-03	89
GO:0043524	GO:0043524	negative regulation of neuron apoptotic process	36/2060	86/8135	1.65	5.52e-04	4.42e-03	86
GO:0051952	GO:0051952	regulation of amine transport	33/2060	77/8135	1.69	5.60e-04	4.48e-03	77
GO:0050873	GO:0050873	brown fat cell differentiation	16/2060	29/8135	2.18	5.67e-04	4.52e-03	29
GO:0010827	GO:0010827	regulation of glucose transmembrane transport	19/2060	37/8135	2.03	5.88e-04	4.66e-03	37
GO:0048247	GO:0048247	lymphocyte chemotaxis	24/2060	51/8135	1.86	6.21e-04	4.89e-03	51
GO:0003044	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	20/2060	40/8135	1.97	6.63e-04	5.17e-03	40
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	20/2060	40/8135	1.97	6.63e-04	5.17e-03	40
GO:1901654	GO:1901654	response to ketone	46/2060	118/8135	1.54	6.92e-04	5.36e-03	118
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	11/2060	17/8135	2.56	6.94e-04	5.37e-03	17
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	27/2060	60/8135	1.78	7.02e-04	5.41e-03	60
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	21/2060	43/8135	1.93	7.30e-04	5.58e-03	43
GO:0050710	GO:0050710	negative regulation of cytokine secretion	21/2060	43/8135	1.93	7.30e-04	5.58e-03	43
GO:0060420	GO:0060420	regulation of heart growth	21/2060	43/8135	1.93	7.30e-04	5.58e-03	43
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	49/2060	128/8135	1.51	7.62e-04	5.79e-03	128
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	13/2060	22/8135	2.33	7.86e-04	5.89e-03	22
GO:0050901	GO:0050901	leukocyte tethering or rolling	13/2060	22/8135	2.33	7.86e-04	5.89e-03	22
GO:0014897	GO:0014897	striated muscle hypertrophy	22/2060	46/8135	1.89	7.88e-04	5.89e-03	46
GO:0046889	GO:0046889	positive regulation of lipid biosynthetic process	22/2060	46/8135	1.89	7.88e-04	5.89e-03	46
GO:0051341	GO:0051341	regulation of oxidoreductase activity	22/2060	46/8135	1.89	7.88e-04	5.89e-03	46
GO:0060395	GO:0060395	SMAD protein signal transduction	22/2060	46/8135	1.89	7.88e-04	5.89e-03	46
GO:1903828	GO:1903828	negative regulation of cellular protein localization	22/2060	46/8135	1.89	7.88e-04	5.89e-03	46
GO:0032330	GO:0032330	regulation of chondrocyte differentiation	18/2060	35/8135	2.03	7.99e-04	5.95e-03	35
GO:0060402	GO:0060402	calcium ion transport into cytosol	41/2060	103/8135	1.57	8.13e-04	6.02e-03	103
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	47/2060	122/8135	1.52	8.24e-04	6.09e-03	122
GO:0042698	GO:0042698	ovulation cycle	23/2060	49/8135	1.85	8.38e-04	6.18e-03	49
GO:0032332	GO:0032332	positive regulation of chondrocyte differentiation	10/2060	15/8135	2.63	8.77e-04	6.34e-03	15
GO:0060669	GO:0060669	embryonic placenta morphogenesis	10/2060	15/8135	2.63	8.77e-04	6.34e-03	15
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	10/2060	15/8135	2.63	8.77e-04	6.34e-03	15
GO:0034308	GO:0034308	primary alcohol metabolic process	24/2060	52/8135	1.82	8.80e-04	6.34e-03	52
GO:0060291	GO:0060291	long-term synaptic potentiation	24/2060	52/8135	1.82	8.80e-04	6.34e-03	52
GO:2000379	GO:2000379	positive regulation of reactive oxygen species metabolic process	24/2060	52/8135	1.82	8.80e-04	6.34e-03	52
GO:0062014	GO:0062014	negative regulation of small molecule metabolic process	25/2060	55/8135	1.80	9.14e-04	6.53e-03	55
GO:0042088	GO:0042088	T-helper 1 type immune response	16/2060	30/8135	2.11	9.32e-04	6.63e-03	30
GO:0019233	GO:0019233	sensory perception of pain	34/2060	82/8135	1.64	9.52e-04	6.75e-03	82
GO:0090090	GO:0090090	negative regulation of canonical Wnt signaling pathway	33/2060	79/8135	1.65	9.65e-04	6.82e-03	79
GO:0050709	GO:0050709	negative regulation of protein secretion	32/2060	76/8135	1.66	9.74e-04	6.86e-03	76
GO:0034332	GO:0034332	adherens junction organization	29/2060	67/8135	1.71	9.80e-04	6.86e-03	67
GO:0002456	GO:0002456	T cell mediated immunity	30/2060	70/8135	1.69	9.82e-04	6.86e-03	70
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	30/2060	70/8135	1.69	9.82e-04	6.86e-03	70
GO:0071456	GO:0071456	cellular response to hypoxia	30/2060	70/8135	1.69	9.82e-04	6.86e-03	70
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	14/2060	25/8135	2.21	1.03e-03	7.13e-03	25
GO:0010883	GO:0010883	regulation of lipid storage	14/2060	25/8135	2.21	1.03e-03	7.13e-03	25
GO:0061614	GO:0061614	pri-miRNA transcription by RNA polymerase II	14/2060	25/8135	2.21	1.03e-03	7.13e-03	25
GO:0098801	GO:0098801	regulation of renal system process	14/2060	25/8135	2.21	1.03e-03	7.13e-03	25
GO:0002026	GO:0002026	regulation of the force of heart contraction	12/2060	20/8135	2.37	1.04e-03	7.16e-03	20
GO:0043114	GO:0043114	regulation of vascular permeability	12/2060	20/8135	2.37	1.04e-03	7.16e-03	20
GO:0050999	GO:0050999	regulation of nitric-oxide synthase activity	12/2060	20/8135	2.37	1.04e-03	7.16e-03	20
GO:0014074	GO:0014074	response to purine-containing compound	40/2060	101/8135	1.56	1.05e-03	7.20e-03	101
GO:0003300	GO:0003300	cardiac muscle hypertrophy	21/2060	44/8135	1.88	1.07e-03	7.26e-03	44
GO:1900180	GO:1900180	regulation of protein localization to nucleus	21/2060	44/8135	1.88	1.07e-03	7.26e-03	44
GO:0070293	GO:0070293	renal absorption	9/2060	13/8135	2.73	1.08e-03	7.35e-03	13
GO:0045833	GO:0045833	negative regulation of lipid metabolic process	22/2060	47/8135	1.85	1.13e-03	7.64e-03	47
GO:0050777	GO:0050777	negative regulation of immune response	36/2060	89/8135	1.60	1.17e-03	7.89e-03	89
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	36/2060	89/8135	1.60	1.17e-03	7.89e-03	89
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	35/2060	86/8135	1.61	1.20e-03	8.02e-03	86
GO:0001913	GO:0001913	T cell mediated cytotoxicity	18/2060	36/8135	1.97	1.22e-03	8.09e-03	36
GO:0006953	GO:0006953	acute-phase response	18/2060	36/8135	1.97	1.22e-03	8.09e-03	36
GO:0043949	GO:0043949	regulation of cAMP-mediated signaling	18/2060	36/8135	1.97	1.22e-03	8.09e-03	36
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	24/2060	53/8135	1.79	1.23e-03	8.09e-03	53
GO:0055024	GO:0055024	regulation of cardiac muscle tissue development	24/2060	53/8135	1.79	1.23e-03	8.09e-03	53
GO:0032649	GO:0032649	regulation of interferon-gamma production	33/2060	80/8135	1.63	1.25e-03	8.19e-03	80
GO:0072676	GO:0072676	lymphocyte migration	33/2060	80/8135	1.63	1.25e-03	8.19e-03	80
GO:0014743	GO:0014743	regulation of muscle hypertrophy	15/2060	28/8135	2.12	1.26e-03	8.23e-03	28
GO:0042089	GO:0042089	cytokine biosynthetic process	32/2060	77/8135	1.64	1.27e-03	8.23e-03	77
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	32/2060	77/8135	1.64	1.27e-03	8.23e-03	77
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	32/2060	77/8135	1.64	1.27e-03	8.23e-03	77
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	26/2060	59/8135	1.74	1.28e-03	8.28e-03	59
GO:0071901	GO:0071901	negative regulation of protein serine/threonine kinase activity	26/2060	59/8135	1.74	1.28e-03	8.28e-03	59
GO:0043371	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	8/2060	11/8135	2.87	1.29e-03	8.28e-03	11
GO:0044126	GO:0044126	regulation of growth of symbiont in host	8/2060	11/8135	2.87	1.29e-03	8.28e-03	11
GO:0044130	GO:0044130	negative regulation of growth of symbiont in host	8/2060	11/8135	2.87	1.29e-03	8.28e-03	11
GO:1903671	GO:1903671	negative regulation of sprouting angiogenesis	8/2060	11/8135	2.87	1.29e-03	8.28e-03	11
GO:0036294	GO:0036294	cellular response to decreased oxygen levels	30/2060	71/8135	1.67	1.30e-03	8.28e-03	71
GO:0031341	GO:0031341	regulation of cell killing	29/2060	68/8135	1.68	1.30e-03	8.30e-03	68
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	19/2060	39/8135	1.92	1.34e-03	8.51e-03	39
GO:0071398	GO:0071398	cellular response to fatty acid	19/2060	39/8135	1.92	1.34e-03	8.51e-03	39
GO:0051402	GO:0051402	neuron apoptotic process	45/2060	118/8135	1.51	1.34e-03	8.51e-03	118
GO:0061082	GO:0061082	myeloid leukocyte cytokine production	11/2060	18/8135	2.41	1.38e-03	8.70e-03	18
GO:0042311	GO:0042311	vasodilation	13/2060	23/8135	2.23	1.39e-03	8.74e-03	23
GO:0043618	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	13/2060	23/8135	2.23	1.39e-03	8.74e-03	23
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	13/2060	23/8135	2.23	1.39e-03	8.74e-03	23
GO:1904035	GO:1904035	regulation of epithelial cell apoptotic process	20/2060	42/8135	1.88	1.44e-03	9.01e-03	42
GO:0086009	GO:0086009	membrane repolarization	16/2060	31/8135	2.04	1.48e-03	9.17e-03	31
GO:0050810	GO:0050810	regulation of steroid biosynthetic process	21/2060	45/8135	1.84	1.53e-03	9.43e-03	45
GO:1905952	GO:1905952	regulation of lipid localization	35/2060	87/8135	1.59	1.53e-03	9.43e-03	87
GO:0048634	GO:0048634	regulation of muscle organ development	34/2060	84/8135	1.60	1.57e-03	9.63e-03	84
GO:0014896	GO:0014896	muscle hypertrophy	22/2060	48/8135	1.81	1.60e-03	9.78e-03	48
GO:0016125	GO:0016125	sterol metabolic process	33/2060	81/8135	1.61	1.60e-03	9.82e-03	81
GO:0008360	GO:0008360	regulation of cell shape	32/2060	78/8135	1.62	1.64e-03	9.90e-03	78
GO:0042107	GO:0042107	cytokine metabolic process	32/2060	78/8135	1.62	1.64e-03	9.90e-03	78
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	32/2060	78/8135	1.62	1.64e-03	9.90e-03	78
GO:0002686	GO:0002686	negative regulation of leukocyte migration	17/2060	34/8135	1.97	1.66e-03	9.98e-03	34
GO:0045843	GO:0045843	negative regulation of striated muscle tissue development	17/2060	34/8135	1.97	1.66e-03	9.98e-03	34
GO:0048635	GO:0048635	negative regulation of muscle organ development	17/2060	34/8135	1.97	1.66e-03	9.98e-03	34
GO:1905954	GO:1905954	positive regulation of lipid localization	24/2060	54/8135	1.76	1.69e-03	1.01e-02	54
GO:0035296	GO:0035296	regulation of tube diameter	39/2060	100/8135	1.54	1.69e-03	1.01e-02	100
GO:0097746	GO:0097746	regulation of blood vessel diameter	39/2060	100/8135	1.54	1.69e-03	1.01e-02	100
GO:0015980	GO:0015980	energy derivation by oxidation of organic compounds	29/2060	69/8135	1.66	1.71e-03	1.02e-02	69
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	25/2060	57/8135	1.73	1.71e-03	1.02e-02	57
GO:0043620	GO:0043620	regulation of DNA-templated transcription in response to stress	14/2060	26/8135	2.13	1.72e-03	1.02e-02	26
GO:0046323	GO:0046323	glucose import	14/2060	26/8135	2.13	1.72e-03	1.02e-02	26
GO:1903428	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	14/2060	26/8135	2.13	1.72e-03	1.02e-02	26
GO:0072659	GO:0072659	protein localization to plasma membrane	43/2060	113/8135	1.50	1.79e-03	1.05e-02	113
GO:1903708	GO:1903708	positive regulation of hemopoiesis	43/2060	113/8135	1.50	1.79e-03	1.05e-02	113
GO:0003298	GO:0003298	physiological muscle hypertrophy	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0003301	GO:0003301	physiological cardiac muscle hypertrophy	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0061049	GO:0061049	cell growth involved in cardiac muscle cell development	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0071379	GO:0071379	cellular response to prostaglandin stimulus	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0071677	GO:0071677	positive regulation of mononuclear cell migration	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0071875	GO:0071875	adrenergic receptor signaling pathway	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0072111	GO:0072111	cell proliferation involved in kidney development	10/2060	16/8135	2.47	1.81e-03	1.05e-02	16
GO:0001706	GO:0001706	endoderm formation	18/2060	37/8135	1.92	1.82e-03	1.05e-02	37
GO:0042093	GO:0042093	T-helper cell differentiation	18/2060	37/8135	1.92	1.82e-03	1.05e-02	37
GO:0055021	GO:0055021	regulation of cardiac muscle tissue growth	18/2060	37/8135	1.92	1.82e-03	1.05e-02	37
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	36/2060	91/8135	1.56	1.87e-03	1.07e-02	91
GO:0043267	GO:0043267	negative regulation of potassium ion transport	12/2060	21/8135	2.26	1.88e-03	1.07e-02	21
GO:0060317	GO:0060317	cardiac epithelial to mesenchymal transition	12/2060	21/8135	2.26	1.88e-03	1.07e-02	21
GO:0061036	GO:0061036	positive regulation of cartilage development	12/2060	21/8135	2.26	1.88e-03	1.07e-02	21
GO:1902932	GO:1902932	positive regulation of alcohol biosynthetic process	12/2060	21/8135	2.26	1.88e-03	1.07e-02	21
GO:2000725	GO:2000725	regulation of cardiac muscle cell differentiation	12/2060	21/8135	2.26	1.88e-03	1.07e-02	21
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	19/2060	40/8135	1.88	1.96e-03	1.10e-02	40
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	19/2060	40/8135	1.88	1.96e-03	1.10e-02	40
GO:0032722	GO:0032722	positive regulation of chemokine production	19/2060	40/8135	1.88	1.96e-03	1.10e-02	40
GO:0045600	GO:0045600	positive regulation of fat cell differentiation	19/2060	40/8135	1.88	1.96e-03	1.10e-02	40
GO:0060389	GO:0060389	pathway-restricted SMAD protein phosphorylation	19/2060	40/8135	1.88	1.96e-03	1.10e-02	40
GO:0001885	GO:0001885	endothelial cell development	15/2060	29/8135	2.04	2.01e-03	1.13e-02	29
GO:0016202	GO:0016202	regulation of striated muscle tissue development	33/2060	82/8135	1.59	2.04e-03	1.14e-02	82
GO:0043255	GO:0043255	regulation of carbohydrate biosynthetic process	20/2060	43/8135	1.84	2.07e-03	1.15e-02	43
GO:0045123	GO:0045123	cellular extravasation	20/2060	43/8135	1.84	2.07e-03	1.15e-02	43
GO:0051208	GO:0051208	sequestering of calcium ion	32/2060	79/8135	1.60	2.10e-03	1.16e-02	79
GO:0071453	GO:0071453	cellular response to oxygen levels	32/2060	79/8135	1.60	2.10e-03	1.16e-02	79
GO:0030178	GO:0030178	negative regulation of Wnt signaling pathway	38/2060	98/8135	1.53	2.18e-03	1.20e-02	98
GO:0050868	GO:0050868	negative regulation of T cell activation	28/2060	67/8135	1.65	2.26e-03	1.24e-02	67
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	16/2060	32/8135	1.97	2.27e-03	1.24e-02	32
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	26/2060	61/8135	1.68	2.29e-03	1.25e-02	61
GO:0051937	GO:0051937	catecholamine transport	26/2060	61/8135	1.68	2.29e-03	1.25e-02	61
GO:0090100	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	25/2060	58/8135	1.70	2.29e-03	1.25e-02	58
GO:0006635	GO:0006635	fatty acid beta-oxidation	13/2060	24/8135	2.14	2.34e-03	1.26e-02	24
GO:1902622	GO:1902622	regulation of neutrophil migration	13/2060	24/8135	2.14	2.34e-03	1.26e-02	24
GO:0006006	GO:0006006	glucose metabolic process	36/2060	92/8135	1.55	2.34e-03	1.26e-02	92
GO:0002043	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0031649	GO:0031649	heat generation	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0043951	GO:0043951	negative regulation of cAMP-mediated signaling	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0048305	GO:0048305	immunoglobulin secretion	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0061437	GO:0061437	renal system vasculature development	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0061440	GO:0061440	kidney vasculature development	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0072012	GO:0072012	glomerulus vasculature development	9/2060	14/8135	2.54	2.35e-03	1.26e-02	14
GO:0042133	GO:0042133	neurotransmitter metabolic process	35/2060	89/8135	1.55	2.42e-03	1.29e-02	89
GO:0050715	GO:0050715	positive regulation of cytokine secretion	35/2060	89/8135	1.55	2.42e-03	1.29e-02	89
GO:0072577	GO:0072577	endothelial cell apoptotic process	17/2060	35/8135	1.92	2.48e-03	1.32e-02	35
GO:0010922	GO:0010922	positive regulation of phosphatase activity	11/2060	19/8135	2.29	2.53e-03	1.33e-02	19
GO:0090025	GO:0090025	regulation of monocyte chemotaxis	11/2060	19/8135	2.29	2.53e-03	1.33e-02	19
GO:0090317	GO:0090317	negative regulation of intracellular protein transport	11/2060	19/8135	2.29	2.53e-03	1.33e-02	19
GO:0006970	GO:0006970	response to osmotic stress	18/2060	38/8135	1.87	2.66e-03	1.39e-02	38
GO:0042306	GO:0042306	regulation of protein import into nucleus	14/2060	27/8135	2.05	2.75e-03	1.43e-02	27
GO:1904589	GO:1904589	regulation of protein import	14/2060	27/8135	2.05	2.75e-03	1.43e-02	27
GO:0008277	GO:0008277	regulation of G protein-coupled receptor signaling pathway	37/2060	96/8135	1.52	2.80e-03	1.45e-02	96
GO:0046165	GO:0046165	alcohol biosynthetic process	29/2060	71/8135	1.61	2.87e-03	1.48e-02	71
GO:0098754	GO:0098754	detoxification	29/2060	71/8135	1.61	2.87e-03	1.48e-02	71
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	20/2060	44/8135	1.80	2.90e-03	1.49e-02	44
GO:0045732	GO:0045732	positive regulation of protein catabolic process	28/2060	68/8135	1.63	2.93e-03	1.51e-02	68
GO:0046888	GO:0046888	negative regulation of hormone secretion	21/2060	47/8135	1.76	2.97e-03	1.52e-02	47
GO:0032612	GO:0032612	interleukin-1 production	27/2060	65/8135	1.64	2.97e-03	1.52e-02	65
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0044144	GO:0044144	modulation of growth of symbiont involved in interaction with host	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0044146	GO:0044146	negative regulation of growth of symbiont involved in interaction with host	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0061298	GO:0061298	retina vasculature development in camera-type eye	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0071711	GO:0071711	basement membrane organization	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0090493	GO:0090493	catecholamine uptake	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0090494	GO:0090494	dopamine uptake	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:1904994	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	8/2060	12/8135	2.63	3.02e-03	1.52e-02	12
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	35/2060	90/8135	1.54	3.02e-03	1.52e-02	90
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	35/2060	90/8135	1.54	3.02e-03	1.52e-02	90
GO:0097306	GO:0097306	cellular response to alcohol	22/2060	50/8135	1.74	3.02e-03	1.52e-02	50
GO:0033555	GO:0033555	multicellular organismal response to stress	23/2060	53/8135	1.71	3.05e-03	1.53e-02	53
GO:1904019	GO:1904019	epithelial cell apoptotic process	23/2060	53/8135	1.71	3.05e-03	1.53e-02	53
GO:0022617	GO:0022617	extracellular matrix disassembly	24/2060	56/8135	1.69	3.05e-03	1.53e-02	56
GO:0098869	GO:0098869	cellular oxidant detoxification	24/2060	56/8135	1.69	3.05e-03	1.53e-02	56
GO:0002720	GO:0002720	positive regulation of cytokine production involved in immune response	15/2060	30/8135	1.97	3.09e-03	1.54e-02	30
GO:0010633	GO:0010633	negative regulation of epithelial cell migration	15/2060	30/8135	1.97	3.09e-03	1.54e-02	30
GO:1902905	GO:1902905	positive regulation of supramolecular fiber organization	34/2060	87/8135	1.54	3.13e-03	1.56e-02	87
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	12/2060	22/8135	2.15	3.18e-03	1.58e-02	22
GO:1901861	GO:1901861	regulation of muscle tissue development	33/2060	84/8135	1.55	3.24e-03	1.61e-02	84
GO:0001890	GO:0001890	placenta development	32/2060	81/8135	1.56	3.35e-03	1.65e-02	81
GO:0006109	GO:0006109	regulation of carbohydrate metabolic process	32/2060	81/8135	1.56	3.35e-03	1.65e-02	81
GO:0035987	GO:0035987	endodermal cell differentiation	16/2060	33/8135	1.91	3.38e-03	1.66e-02	33
GO:0070301	GO:0070301	cellular response to hydrogen peroxide	16/2060	33/8135	1.91	3.38e-03	1.66e-02	33
GO:1905207	GO:1905207	regulation of cardiocyte differentiation	16/2060	33/8135	1.91	3.38e-03	1.66e-02	33
GO:0034695	GO:0034695	response to prostaglandin E	10/2060	17/8135	2.32	3.40e-03	1.66e-02	17
GO:0051491	GO:0051491	positive regulation of filopodium assembly	10/2060	17/8135	2.32	3.40e-03	1.66e-02	17
GO:0097009	GO:0097009	energy homeostasis	10/2060	17/8135	2.32	3.40e-03	1.66e-02	17
GO:0016050	GO:0016050	vesicle organization	37/2060	97/8135	1.51	3.44e-03	1.67e-02	97
GO:0016999	GO:0016999	antibiotic metabolic process	31/2060	78/8135	1.57	3.46e-03	1.67e-02	78
GO:0032615	GO:0032615	interleukin-12 production	17/2060	36/8135	1.86	3.61e-03	1.73e-02	36
GO:0044060	GO:0044060	regulation of endocrine process	17/2060	36/8135	1.86	3.61e-03	1.73e-02	36
GO:1901862	GO:1901862	negative regulation of muscle tissue development	17/2060	36/8135	1.86	3.61e-03	1.73e-02	36
GO:0015844	GO:0015844	monoamine transport	29/2060	72/8135	1.59	3.66e-03	1.75e-02	72
GO:0043433	GO:0043433	negative regulation of DNA-binding transcription factor activity	29/2060	72/8135	1.59	3.66e-03	1.75e-02	72
GO:0032635	GO:0032635	interleukin-6 production	35/2060	91/8135	1.52	3.73e-03	1.76e-02	91
GO:0035306	GO:0035306	positive regulation of dephosphorylation	13/2060	25/8135	2.05	3.75e-03	1.76e-02	25
GO:0043277	GO:0043277	apoptotic cell clearance	13/2060	25/8135	2.05	3.75e-03	1.76e-02	25
GO:0045581	GO:0045581	negative regulation of T cell differentiation	13/2060	25/8135	2.05	3.75e-03	1.76e-02	25
GO:0010675	GO:0010675	regulation of cellular carbohydrate metabolic process	28/2060	69/8135	1.60	3.75e-03	1.76e-02	69
GO:0010614	GO:0010614	negative regulation of cardiac muscle hypertrophy	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:0010878	GO:0010878	cholesterol storage	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:0036303	GO:0036303	lymph vessel morphogenesis	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:0045623	GO:0045623	negative regulation of T-helper cell differentiation	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:0072203	GO:0072203	cell proliferation involved in metanephros development	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:1903587	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:2000833	GO:2000833	positive regulation of steroid hormone secretion	7/2060	10/8135	2.76	3.77e-03	1.76e-02	10
GO:1901888	GO:1901888	regulation of cell junction assembly	18/2060	39/8135	1.82	3.78e-03	1.77e-02	39
GO:0006641	GO:0006641	triglyceride metabolic process	27/2060	66/8135	1.62	3.84e-03	1.79e-02	66
GO:1903076	GO:1903076	regulation of protein localization to plasma membrane	19/2060	42/8135	1.79	3.91e-03	1.82e-02	42
GO:0034763	GO:0034763	negative regulation of transmembrane transport	26/2060	63/8135	1.63	3.92e-03	1.82e-02	63
GO:0032637	GO:0032637	interleukin-8 production	20/2060	45/8135	1.76	4.00e-03	1.85e-02	45
GO:0051101	GO:0051101	regulation of DNA binding	24/2060	57/8135	1.66	4.03e-03	1.86e-02	57
GO:0032675	GO:0032675	regulation of interleukin-6 production	33/2060	85/8135	1.53	4.03e-03	1.86e-02	85
GO:0032611	GO:0032611	interleukin-1 beta production	23/2060	54/8135	1.68	4.06e-03	1.86e-02	54
GO:0051966	GO:0051966	regulation of synaptic transmission, glutamatergic	23/2060	54/8135	1.68	4.06e-03	1.86e-02	54
GO:0051149	GO:0051149	positive regulation of muscle cell differentiation	22/2060	51/8135	1.70	4.07e-03	1.86e-02	51
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	31/2060	79/8135	1.55	4.34e-03	1.97e-02	79
GO:0035929	GO:0035929	steroid hormone secretion	11/2060	20/8135	2.17	4.34e-03	1.97e-02	20
GO:0071276	GO:0071276	cellular response to cadmium ion	11/2060	20/8135	2.17	4.34e-03	1.97e-02	20
GO:0032526	GO:0032526	response to retinoic acid	30/2060	76/8135	1.56	4.49e-03	2.02e-02	76
GO:0001991	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:0046639	GO:0046639	negative regulation of alpha-beta T cell differentiation	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:0055022	GO:0055022	negative regulation of cardiac muscle tissue growth	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:0061117	GO:0061117	negative regulation of heart growth	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:0071880	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:1900181	GO:1900181	negative regulation of protein localization to nucleus	9/2060	15/8135	2.37	4.57e-03	2.04e-02	15
GO:0050994	GO:0050994	regulation of lipid catabolic process	15/2060	31/8135	1.91	4.61e-03	2.05e-02	31
GO:0045580	GO:0045580	regulation of T cell differentiation	34/2060	89/8135	1.51	4.78e-03	2.12e-02	89
GO:0032640	GO:0032640	tumor necrosis factor production	33/2060	86/8135	1.52	4.98e-03	2.20e-02	86
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	33/2060	86/8135	1.52	4.98e-03	2.20e-02	86
GO:0002286	GO:0002286	T cell activation involved in immune response	26/2060	64/8135	1.60	5.04e-03	2.22e-02	64
GO:0051153	GO:0051153	regulation of striated muscle cell differentiation	26/2060	64/8135	1.60	5.04e-03	2.22e-02	64
GO:0055026	GO:0055026	negative regulation of cardiac muscle tissue development	12/2060	23/8135	2.06	5.14e-03	2.25e-02	23
GO:1903523	GO:1903523	negative regulation of blood circulation	12/2060	23/8135	2.06	5.14e-03	2.25e-02	23
GO:0072329	GO:0072329	monocarboxylic acid catabolic process	25/2060	61/8135	1.62	5.15e-03	2.26e-02	61
GO:1990748	GO:1990748	cellular detoxification	24/2060	58/8135	1.63	5.25e-03	2.29e-02	58
GO:0032677	GO:0032677	regulation of interleukin-8 production	18/2060	40/8135	1.78	5.27e-03	2.30e-02	40
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	19/2060	43/8135	1.74	5.37e-03	2.34e-02	43
GO:0001823	GO:0001823	mesonephros development	31/2060	80/8135	1.53	5.40e-03	2.34e-02	80
GO:0050918	GO:0050918	positive chemotaxis	21/2060	49/8135	1.69	5.42e-03	2.35e-02	49
GO:1904375	GO:1904375	regulation of protein localization to cell periphery	21/2060	49/8135	1.69	5.42e-03	2.35e-02	49
GO:0030282	GO:0030282	bone mineralization	30/2060	77/8135	1.54	5.60e-03	2.42e-02	77
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	13/2060	26/8135	1.97	5.79e-03	2.48e-02	26
GO:0010543	GO:0010543	regulation of platelet activation	13/2060	26/8135	1.97	5.79e-03	2.48e-02	26
GO:0033762	GO:0033762	response to glucagon	13/2060	26/8135	1.97	5.79e-03	2.48e-02	26
GO:0002673	GO:0002673	regulation of acute inflammatory response	29/2060	74/8135	1.55	5.81e-03	2.49e-02	74
GO:0034405	GO:0034405	response to fluid shear stress	10/2060	18/8135	2.19	5.93e-03	2.53e-02	18
GO:0085029	GO:0085029	extracellular matrix assembly	10/2060	18/8135	2.19	5.93e-03	2.53e-02	18
GO:0098810	GO:0098810	neurotransmitter reuptake	10/2060	18/8135	2.19	5.93e-03	2.53e-02	18
GO:0032682	GO:0032682	negative regulation of chemokine production	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0034390	GO:0034390	smooth muscle cell apoptotic process	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0034391	GO:0034391	regulation of smooth muscle cell apoptotic process	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0060330	GO:0060330	regulation of response to interferon-gamma	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0060334	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0060713	GO:0060713	labyrinthine layer morphogenesis	8/2060	13/8135	2.43	6.11e-03	2.58e-02	13
GO:0003073	GO:0003073	regulation of systemic arterial blood pressure	27/2060	68/8135	1.57	6.22e-03	2.61e-02	68
GO:0033135	GO:0033135	regulation of peptidyl-serine phosphorylation	27/2060	68/8135	1.57	6.22e-03	2.61e-02	68
GO:0043266	GO:0043266	regulation of potassium ion transport	27/2060	68/8135	1.57	6.22e-03	2.61e-02	68
GO:0072028	GO:0072028	nephron morphogenesis	26/2060	65/8135	1.58	6.41e-03	2.68e-02	65
GO:0030316	GO:0030316	osteoclast differentiation	25/2060	62/8135	1.59	6.60e-03	2.75e-02	62
GO:0001990	GO:0001990	regulation of systemic arterial blood pressure by hormone	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0032387	GO:0032387	negative regulation of intracellular transport	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0045620	GO:0045620	negative regulation of lymphocyte differentiation	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0045744	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0061383	GO:0061383	trabecula morphogenesis	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:2000351	GO:2000351	regulation of endothelial cell apoptotic process	15/2060	32/8135	1.85	6.67e-03	2.76e-02	32
GO:0060021	GO:0060021	roof of mouth development	24/2060	59/8135	1.61	6.77e-03	2.78e-02	59
GO:0071236	GO:0071236	cellular response to antibiotic	24/2060	59/8135	1.61	6.77e-03	2.78e-02	59
GO:0046620	GO:0046620	regulation of organ growth	23/2060	56/8135	1.62	6.92e-03	2.83e-02	56
GO:0032655	GO:0032655	regulation of interleukin-12 production	16/2060	35/8135	1.81	6.94e-03	2.83e-02	35
GO:0042743	GO:0042743	hydrogen peroxide metabolic process	16/2060	35/8135	1.81	6.94e-03	2.83e-02	35
GO:0043407	GO:0043407	negative regulation of MAP kinase activity	16/2060	35/8135	1.81	6.94e-03	2.83e-02	35
GO:0051702	GO:0051702	interaction with symbiont	16/2060	35/8135	1.81	6.94e-03	2.83e-02	35
GO:0045778	GO:0045778	positive regulation of ossification	22/2060	53/8135	1.64	7.05e-03	2.86e-02	53
GO:0005978	GO:0005978	glycogen biosynthetic process	11/2060	21/8135	2.07	7.06e-03	2.86e-02	21
GO:0009250	GO:0009250	glucan biosynthetic process	11/2060	21/8135	2.07	7.06e-03	2.86e-02	21
GO:0060393	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	17/2060	38/8135	1.77	7.12e-03	2.87e-02	38
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	17/2060	38/8135	1.77	7.12e-03	2.87e-02	38
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	21/2060	50/8135	1.66	7.16e-03	2.87e-02	50
GO:0034637	GO:0034637	cellular carbohydrate biosynthetic process	18/2060	41/8135	1.73	7.22e-03	2.89e-02	41
GO:0007492	GO:0007492	endoderm development	20/2060	47/8135	1.68	7.22e-03	2.89e-02	47
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	29/2060	75/8135	1.53	7.23e-03	2.89e-02	75
GO:0002292	GO:0002292	T cell differentiation involved in immune response	19/2060	44/8135	1.71	7.25e-03	2.89e-02	44
GO:0010811	GO:0010811	positive regulation of cell-substrate adhesion	28/2060	72/8135	1.54	7.51e-03	2.98e-02	72
GO:0051099	GO:0051099	positive regulation of binding	28/2060	72/8135	1.54	7.51e-03	2.98e-02	72
GO:0055007	GO:0055007	cardiac muscle cell differentiation	28/2060	72/8135	1.54	7.51e-03	2.98e-02	72
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0006699	GO:0006699	bile acid biosynthetic process	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0051489	GO:0051489	regulation of filopodium assembly	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0060976	GO:0060976	coronary vasculature development	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0099084	GO:0099084	postsynaptic specialization organization	12/2060	24/8135	1.97	7.94e-03	3.12e-02	24
GO:0031122	GO:0031122	cytoplasmic microtubule organization	9/2060	16/8135	2.22	8.11e-03	3.14e-02	16
GO:0035812	GO:0035812	renal sodium excretion	9/2060	16/8135	2.22	8.11e-03	3.14e-02	16
GO:0035813	GO:0035813	regulation of renal sodium excretion	9/2060	16/8135	2.22	8.11e-03	3.14e-02	16
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	9/2060	16/8135	2.22	8.11e-03	3.14e-02	16
GO:0045601	GO:0045601	regulation of endothelial cell differentiation	9/2060	16/8135	2.22	8.11e-03	3.14e-02	16
GO:0010934	GO:0010934	macrophage cytokine production	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:0031648	GO:0031648	protein destabilization	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:0033605	GO:0033605	positive regulation of catecholamine secretion	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:0060390	GO:0060390	regulation of SMAD protein signal transduction	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:0070493	GO:0070493	thrombin-activated receptor signaling pathway	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:1901889	GO:1901889	negative regulation of cell junction assembly	7/2060	11/8135	2.51	8.11e-03	3.14e-02	11
GO:0019218	GO:0019218	regulation of steroid metabolic process	25/2060	63/8135	1.57	8.36e-03	3.22e-02	63
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	25/2060	63/8135	1.57	8.36e-03	3.22e-02	63
GO:0072088	GO:0072088	nephron epithelium morphogenesis	25/2060	63/8135	1.57	8.36e-03	3.22e-02	63
GO:0002090	GO:0002090	regulation of receptor internalization	13/2060	27/8135	1.90	8.61e-03	3.29e-02	27
GO:0019934	GO:0019934	cGMP-mediated signaling	13/2060	27/8135	1.90	8.61e-03	3.29e-02	27
GO:0045824	GO:0045824	negative regulation of innate immune response	13/2060	27/8135	1.90	8.61e-03	3.29e-02	27
GO:0017038	GO:0017038	protein import	24/2060	60/8135	1.58	8.63e-03	3.29e-02	60
GO:0042136	GO:0042136	neurotransmitter biosynthetic process	24/2060	60/8135	1.58	8.63e-03	3.29e-02	60
GO:0002028	GO:0002028	regulation of sodium ion transport	23/2060	57/8135	1.59	8.88e-03	3.37e-02	57
GO:0001657	GO:0001657	ureteric bud development	29/2060	76/8135	1.51	8.92e-03	3.37e-02	76
GO:0044344	GO:0044344	cellular response to fibroblast growth factor stimulus	29/2060	76/8135	1.51	8.92e-03	3.37e-02	76
GO:0072163	GO:0072163	mesonephric epithelium development	29/2060	76/8135	1.51	8.92e-03	3.37e-02	76
GO:0072164	GO:0072164	mesonephric tubule development	29/2060	76/8135	1.51	8.92e-03	3.37e-02	76
GO:0005977	GO:0005977	glycogen metabolic process	14/2060	30/8135	1.84	9.09e-03	3.43e-02	30
GO:0010862	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	14/2060	30/8135	1.84	9.09e-03	3.43e-02	30
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	22/2060	54/8135	1.61	9.11e-03	3.43e-02	54
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	22/2060	54/8135	1.61	9.11e-03	3.43e-02	54
GO:0050432	GO:0050432	catecholamine secretion	21/2060	51/8135	1.63	9.32e-03	3.50e-02	51
GO:0050433	GO:0050433	regulation of catecholamine secretion	21/2060	51/8135	1.63	9.32e-03	3.50e-02	51
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	21/2060	51/8135	1.63	9.32e-03	3.50e-02	51
GO:0010660	GO:0010660	regulation of muscle cell apoptotic process	15/2060	33/8135	1.80	9.42e-03	3.51e-02	33
GO:0033692	GO:0033692	cellular polysaccharide biosynthetic process	15/2060	33/8135	1.80	9.42e-03	3.51e-02	33
GO:1904705	GO:1904705	regulation of vascular smooth muscle cell proliferation	15/2060	33/8135	1.80	9.42e-03	3.51e-02	33
GO:1990874	GO:1990874	vascular smooth muscle cell proliferation	15/2060	33/8135	1.80	9.42e-03	3.51e-02	33
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	16/2060	36/8135	1.76	9.61e-03	3.55e-02	36
GO:0060761	GO:0060761	negative regulation of response to cytokine stimulus	16/2060	36/8135	1.76	9.61e-03	3.55e-02	36
GO:0032231	GO:0032231	regulation of actin filament bundle assembly	19/2060	45/8135	1.67	9.62e-03	3.55e-02	45
GO:0048145	GO:0048145	regulation of fibroblast proliferation	19/2060	45/8135	1.67	9.62e-03	3.55e-02	45
GO:0008630	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	18/2060	42/8135	1.69	9.69e-03	3.55e-02	42
GO:0045667	GO:0045667	regulation of osteoblast differentiation	27/2060	70/8135	1.52	9.70e-03	3.55e-02	70
GO:0046632	GO:0046632	alpha-beta T cell differentiation	27/2060	70/8135	1.52	9.70e-03	3.55e-02	70
GO:0050680	GO:0050680	negative regulation of epithelial cell proliferation	27/2060	70/8135	1.52	9.70e-03	3.55e-02	70
GO:0001893	GO:0001893	maternal placenta development	10/2060	19/8135	2.08	9.71e-03	3.55e-02	19
GO:0035767	GO:0035767	endothelial cell chemotaxis	10/2060	19/8135	2.08	9.71e-03	3.55e-02	19
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	10/2060	19/8135	2.08	9.71e-03	3.55e-02	19
GO:0072215	GO:0072215	regulation of metanephros development	10/2060	19/8135	2.08	9.71e-03	3.55e-02	19
GO:0072539	GO:0072539	T-helper 17 cell differentiation	10/2060	19/8135	2.08	9.71e-03	3.55e-02	19
GO:0030193	GO:0030193	regulation of blood coagulation	25/2060	64/8135	1.54	1.05e-02	3.79e-02	64
GO:1900046	GO:1900046	regulation of hemostasis	25/2060	64/8135	1.54	1.05e-02	3.79e-02	64
GO:0030177	GO:0030177	positive regulation of Wnt signaling pathway	24/2060	61/8135	1.55	1.09e-02	3.90e-02	61
GO:0046545	GO:0046545	development of primary female sexual characteristics	24/2060	61/8135	1.55	1.09e-02	3.90e-02	61
GO:0006706	GO:0006706	steroid catabolic process	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0032660	GO:0032660	regulation of interleukin-17 production	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0038083	GO:0038083	peptidyl-tyrosine autophosphorylation	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0060306	GO:0060306	regulation of membrane repolarization	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0061384	GO:0061384	heart trabecula morphogenesis	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0097106	GO:0097106	postsynaptic density organization	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0097194	GO:0097194	execution phase of apoptosis	11/2060	22/8135	1.97	1.09e-02	3.90e-02	22
GO:0002922	GO:0002922	positive regulation of humoral immune response	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0010544	GO:0010544	negative regulation of platelet activation	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0032098	GO:0032098	regulation of appetite	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0032770	GO:0032770	positive regulation of monooxygenase activity	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0043516	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0044117	GO:0044117	growth of symbiont in host	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:2000846	GO:2000846	regulation of corticosteroid hormone secretion	8/2060	14/8135	2.26	1.11e-02	3.93e-02	14
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	22/2060	55/8135	1.58	1.16e-02	4.09e-02	55
GO:0051170	GO:0051170	import into nucleus	22/2060	55/8135	1.58	1.16e-02	4.09e-02	55
GO:0055006	GO:0055006	cardiac cell development	22/2060	55/8135	1.58	1.16e-02	4.09e-02	55
GO:0072171	GO:0072171	mesonephric tubule morphogenesis	22/2060	55/8135	1.58	1.16e-02	4.09e-02	55
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	12/2060	25/8135	1.90	1.18e-02	4.13e-02	25
GO:0051154	GO:0051154	negative regulation of striated muscle cell differentiation	12/2060	25/8135	1.90	1.18e-02	4.13e-02	25
GO:0051953	GO:0051953	negative regulation of amine transport	12/2060	25/8135	1.90	1.18e-02	4.13e-02	25
GO:0051968	GO:0051968	positive regulation of synaptic transmission, glutamatergic	12/2060	25/8135	1.90	1.18e-02	4.13e-02	25
GO:0035249	GO:0035249	synaptic transmission, glutamatergic	27/2060	71/8135	1.50	1.20e-02	4.17e-02	71
GO:0006606	GO:0006606	protein import into nucleus	21/2060	52/8135	1.59	1.20e-02	4.17e-02	52
GO:0010906	GO:0010906	regulation of glucose metabolic process	21/2060	52/8135	1.59	1.20e-02	4.17e-02	52
GO:0033138	GO:0033138	positive regulation of peptidyl-serine phosphorylation	21/2060	52/8135	1.59	1.20e-02	4.17e-02	52
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	21/2060	52/8135	1.59	1.20e-02	4.17e-02	52
GO:1901655	GO:1901655	cellular response to ketone	21/2060	52/8135	1.59	1.20e-02	4.17e-02	52
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0002820	GO:0002820	negative regulation of adaptive immune response	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0043388	GO:0043388	positive regulation of DNA binding	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0046006	GO:0046006	regulation of activated T cell proliferation	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0051281	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	13/2060	28/8135	1.83	1.24e-02	4.27e-02	28
GO:0007044	GO:0007044	cell-substrate junction assembly	19/2060	46/8135	1.63	1.26e-02	4.31e-02	46
GO:0045913	GO:0045913	positive regulation of carbohydrate metabolic process	19/2060	46/8135	1.63	1.26e-02	4.31e-02	46
GO:0048144	GO:0048144	fibroblast proliferation	19/2060	46/8135	1.63	1.26e-02	4.31e-02	46
GO:0006073	GO:0006073	cellular glucan metabolic process	14/2060	31/8135	1.78	1.28e-02	4.35e-02	31
GO:0006081	GO:0006081	cellular aldehyde metabolic process	14/2060	31/8135	1.78	1.28e-02	4.35e-02	31
GO:0044042	GO:0044042	glucan metabolic process	14/2060	31/8135	1.78	1.28e-02	4.35e-02	31
GO:0048566	GO:0048566	embryonic digestive tract development	14/2060	31/8135	1.78	1.28e-02	4.35e-02	31
GO:0090278	GO:0090278	negative regulation of peptide hormone secretion	14/2060	31/8135	1.78	1.28e-02	4.35e-02	31
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	18/2060	43/8135	1.65	1.28e-02	4.36e-02	43
GO:0110020	GO:0110020	regulation of actomyosin structure organization	17/2060	40/8135	1.68	1.30e-02	4.37e-02	40
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	17/2060	40/8135	1.68	1.30e-02	4.37e-02	40
GO:1902305	GO:1902305	regulation of sodium ion transmembrane transport	17/2060	40/8135	1.68	1.30e-02	4.37e-02	40
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	17/2060	40/8135	1.68	1.30e-02	4.37e-02	40
GO:0000271	GO:0000271	polysaccharide biosynthetic process	15/2060	34/8135	1.74	1.30e-02	4.37e-02	34
GO:0010657	GO:0010657	muscle cell apoptotic process	15/2060	34/8135	1.74	1.30e-02	4.37e-02	34
GO:0010676	GO:0010676	positive regulation of cellular carbohydrate metabolic process	15/2060	34/8135	1.74	1.30e-02	4.37e-02	34
GO:0051851	GO:0051851	modification by host of symbiont morphology or physiology	15/2060	34/8135	1.74	1.30e-02	4.37e-02	34
GO:0072210	GO:0072210	metanephric nephron development	15/2060	34/8135	1.74	1.30e-02	4.37e-02	34
GO:0019319	GO:0019319	hexose biosynthetic process	16/2060	37/8135	1.71	1.30e-02	4.37e-02	37
GO:0060986	GO:0060986	endocrine hormone secretion	16/2060	37/8135	1.71	1.30e-02	4.37e-02	37
GO:0007043	GO:0007043	cell-cell junction assembly	25/2060	65/8135	1.52	1.30e-02	4.37e-02	65
GO:0050818	GO:0050818	regulation of coagulation	25/2060	65/8135	1.52	1.30e-02	4.37e-02	65
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	25/2060	65/8135	1.52	1.30e-02	4.37e-02	65
GO:0001516	GO:0001516	prostaglandin biosynthetic process	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:0042533	GO:0042533	tumor necrosis factor biosynthetic process	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:0042534	GO:0042534	regulation of tumor necrosis factor biosynthetic process	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:0046457	GO:0046457	prostanoid biosynthetic process	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:0046621	GO:0046621	negative regulation of organ growth	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:2000831	GO:2000831	regulation of steroid hormone secretion	9/2060	17/8135	2.09	1.34e-02	4.44e-02	17
GO:1904894	GO:1904894	positive regulation of STAT cascade	24/2060	62/8135	1.53	1.36e-02	4.49e-02	62
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	23/2060	59/8135	1.54	1.41e-02	4.67e-02	59
GO:1903524	GO:1903524	positive regulation of blood circulation	22/2060	56/8135	1.55	1.47e-02	4.82e-02	56
GO:1902624	GO:1902624	positive regulation of neutrophil migration	10/2060	20/8135	1.97	1.51e-02	4.94e-02	20
GO:1902893	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	10/2060	20/8135	1.97	1.51e-02	4.94e-02	20
GO:0002702	GO:0002702	positive regulation of production of molecular mediator of immune response	21/2060	53/8135	1.56	1.52e-02	4.95e-02	53
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	21/2060	53/8135	1.56	1.52e-02	4.95e-02	53
GO:0002374	GO:0002374	cytokine secretion involved in immune response	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0006525	GO:0006525	arginine metabolic process	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0014741	GO:0014741	negative regulation of muscle hypertrophy	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0032373	GO:0032373	positive regulation of sterol transport	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0032376	GO:0032376	positive regulation of cholesterol transport	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0051023	GO:0051023	regulation of immunoglobulin secretion	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:0072216	GO:0072216	positive regulation of metanephros development	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12
GO:1900746	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	7/2060	12/8135	2.30	1.53e-02	4.95e-02	12

Factor 15 : 28 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030198	GO:0030198	extracellular matrix organization	152/3118	264/8135	1.50	9.71e-11	4.14e-07	264
GO:0043588	GO:0043588	skin development	140/3118	241/8135	1.52	2.32e-10	4.94e-07	241
GO:0030216	GO:0030216	keratinocyte differentiation	95/3118	162/8135	1.53	9.99e-08	1.06e-04	162
GO:0031424	GO:0031424	keratinization	74/3118	123/8135	1.57	6.50e-07	2.61e-04	123
GO:0070268	GO:0070268	cornification	60/3118	95/8135	1.65	7.36e-07	2.61e-04	95
GO:0034754	GO:0034754	cellular hormone metabolic process	53/3118	87/8135	1.59	1.50e-05	2.66e-03	87
GO:0007044	GO:0007044	cell-substrate junction assembly	32/3118	46/8135	1.81	1.66e-05	2.71e-03	46
GO:0018149	GO:0018149	peptide cross-linking	29/3118	42/8135	1.80	5.15e-05	6.27e-03	42
GO:0030593	GO:0030593	neutrophil chemotaxis	52/3118	90/8135	1.51	1.33e-04	1.23e-02	90
GO:0097306	GO:0097306	cellular response to alcohol	32/3118	50/8135	1.67	2.01e-04	1.68e-02	50
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	33/3118	52/8135	1.66	2.03e-04	1.68e-02	52
GO:0030199	GO:0030199	collagen fibril organization	25/3118	37/8135	1.76	2.91e-04	2.17e-02	37
GO:0030104	GO:0030104	water homeostasis	31/3118	49/8135	1.65	3.42e-04	2.37e-02	49
GO:1902895	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	12/3118	14/8135	2.24	3.79e-04	2.48e-02	14
GO:0071347	GO:0071347	cellular response to interleukin-1	44/3118	76/8135	1.51	4.02e-04	2.56e-02	76
GO:0050680	GO:0050680	negative regulation of epithelial cell proliferation	41/3118	70/8135	1.53	4.50e-04	2.74e-02	70
GO:0035588	GO:0035588	G protein-coupled purinergic receptor signaling pathway	17/3118	23/8135	1.93	5.66e-04	3.13e-02	23
GO:0007566	GO:0007566	embryo implantation	18/3118	25/8135	1.88	6.53e-04	3.52e-02	25
GO:0051893	GO:0051893	regulation of focal adhesion assembly	19/3118	27/8135	1.84	7.30e-04	3.61e-02	27
GO:0090109	GO:0090109	regulation of cell-substrate junction assembly	19/3118	27/8135	1.84	7.30e-04	3.61e-02	27
GO:1903391	GO:1903391	regulation of adherens junction organization	19/3118	27/8135	1.84	7.30e-04	3.61e-02	27
GO:0033561	GO:0033561	regulation of water loss via skin	14/3118	18/8135	2.03	7.66e-04	3.71e-02	18
GO:0061436	GO:0061436	establishment of skin barrier	14/3118	18/8135	2.03	7.66e-04	3.71e-02	18
GO:0030177	GO:0030177	positive regulation of Wnt signaling pathway	36/3118	61/8135	1.54	8.11e-04	3.88e-02	61
GO:0050891	GO:0050891	multicellular organismal water homeostasis	29/3118	47/8135	1.61	9.58e-04	4.26e-02	47
GO:0048546	GO:0048546	digestive tract morphogenesis	25/3118	39/8135	1.67	9.63e-04	4.26e-02	39
GO:1901888	GO:1901888	regulation of cell junction assembly	25/3118	39/8135	1.67	9.63e-04	4.26e-02	39
GO:0006703	GO:0006703	estrogen biosynthetic process	9/3118	10/8135	2.35	1.16e-03	4.80e-02	10

Factor 16 : 3 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0055123	GO:0055123	digestive system development	69/3340	112/8135	1.50	8.10e-06	0.0174	112
GO:0030514	GO:0030514	negative regulation of BMP signaling pathway	25/3340	34/8135	1.79	1.23e-04	0.0439	34
GO:0090101	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	44/3340	70/8135	1.53	1.80e-04	0.0439	70

Factor 17 : 495 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0050778	GO:0050778	positive regulation of immune response	201/1801	423/8135	2.15	1.60e-32	4.68e-29	423
GO:0046649	GO:0046649	lymphocyte activation	192/1801	397/8135	2.18	2.40e-32	4.68e-29	397
GO:0045087	GO:0045087	innate immune response	220/1801	485/8135	2.05	7.07e-32	9.19e-29	485
GO:0002250	GO:0002250	adaptive immune response	146/1801	269/8135	2.45	1.50e-31	1.46e-28	269
GO:0042110	GO:0042110	T cell activation	144/1801	285/8135	2.28	8.37e-27	6.52e-24	285
GO:0002253	GO:0002253	activation of immune response	146/1801	302/8135	2.18	1.21e-24	7.83e-22	302
GO:0002443	GO:0002443	leukocyte mediated immunity	180/1801	410/8135	1.98	5.10e-24	2.84e-21	410
GO:0002764	GO:0002764	immune response-regulating signaling pathway	130/1801	270/8135	2.17	7.97e-22	3.89e-19	270
GO:0051607	GO:0051607	defense response to virus	74/1801	118/8135	2.83	1.61e-21	6.97e-19	118
GO:0002757	GO:0002757	immune response-activating signal transduction	121/1801	249/8135	2.19	8.46e-21	3.30e-18	249
GO:0051249	GO:0051249	regulation of lymphocyte activation	124/1801	260/8135	2.15	2.05e-20	7.26e-18	260
GO:0034340	GO:0034340	response to type I interferon	40/1801	47/8135	3.84	5.39e-20	1.50e-17	47
GO:0060337	GO:0060337	type I interferon signaling pathway	40/1801	47/8135	3.84	5.39e-20	1.50e-17	47
GO:0071357	GO:0071357	cellular response to type I interferon	40/1801	47/8135	3.84	5.39e-20	1.50e-17	47
GO:0009615	GO:0009615	response to virus	88/1801	162/8135	2.45	2.09e-19	5.44e-17	162
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	90/1801	168/8135	2.42	2.78e-19	6.77e-17	168
GO:0002366	GO:0002366	leukocyte activation involved in immune response	152/1801	354/8135	1.94	3.07e-19	7.03e-17	354
GO:0002263	GO:0002263	cell activation involved in immune response	152/1801	356/8135	1.93	5.84e-19	1.22e-16	356
GO:0002521	GO:0002521	leukocyte differentiation	140/1801	318/8135	1.99	5.97e-19	1.22e-16	318
GO:0002697	GO:0002697	regulation of immune effector process	118/1801	251/8135	2.12	7.59e-19	1.48e-16	251
GO:0050863	GO:0050863	regulation of T cell activation	101/1801	203/8135	2.25	1.89e-18	3.50e-16	203
GO:0098542	GO:0098542	defense response to other organism	122/1801	268/8135	2.06	4.85e-18	8.59e-16	268
GO:0002694	GO:0002694	regulation of leukocyte activation	137/1801	316/8135	1.96	7.38e-18	1.25e-15	316
GO:0031347	GO:0031347	regulation of defense response	170/1801	425/8135	1.81	1.17e-17	1.90e-15	425
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	179/1801	459/8135	1.76	3.16e-17	4.93e-15	459
GO:0001816	GO:0001816	cytokine production	174/1801	444/8135	1.77	5.21e-17	7.81e-15	444
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	93/1801	189/8135	2.22	1.11e-16	1.61e-14	189
GO:0050865	GO:0050865	regulation of cell activation	142/1801	344/8135	1.86	3.05e-16	4.25e-14	344
GO:0070661	GO:0070661	leukocyte proliferation	93/1801	193/8135	2.18	6.14e-16	8.13e-14	193
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	94/1801	196/8135	2.17	6.26e-16	8.13e-14	196
GO:0019882	GO:0019882	antigen processing and presentation	52/1801	83/8135	2.83	1.81e-15	2.27e-13	83
GO:0030098	GO:0030098	lymphocyte differentiation	99/1801	214/8135	2.09	2.07e-15	2.52e-13	214
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	83/1801	167/8135	2.24	2.45e-15	2.89e-13	167
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	100/1801	218/8135	2.07	2.98e-15	3.41e-13	218
GO:0034341	GO:0034341	response to interferon-gamma	68/1801	126/8135	2.44	4.39e-15	4.89e-13	126
GO:0030097	GO:0030097	hemopoiesis	173/1801	459/8135	1.70	5.12e-15	5.54e-13	459
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	61/1801	108/8135	2.55	6.93e-15	7.30e-13	108
GO:0001817	GO:0001817	regulation of cytokine production	157/1801	406/8135	1.75	8.01e-15	8.05e-13	406
GO:0002449	GO:0002449	lymphocyte mediated immunity	80/1801	161/8135	2.24	8.05e-15	8.05e-13	161
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	83/1801	170/8135	2.21	9.10e-15	8.87e-13	170
GO:0050870	GO:0050870	positive regulation of T cell activation	72/1801	139/8135	2.34	1.17e-14	1.11e-12	139
GO:0002683	GO:0002683	negative regulation of immune system process	116/1801	273/8135	1.92	1.63e-14	1.51e-12	273
GO:0048534	GO:0048534	hematopoietic or lymphoid organ development	179/1801	487/8135	1.66	2.62e-14	2.37e-12	487
GO:0032943	GO:0032943	mononuclear cell proliferation	85/1801	179/8135	2.14	3.30e-14	2.92e-12	179
GO:0045088	GO:0045088	regulation of innate immune response	91/1801	198/8135	2.08	4.76e-14	4.12e-12	198
GO:0002274	GO:0002274	myeloid leukocyte activation	131/1801	328/8135	1.80	9.46e-14	8.02e-12	328
GO:0046651	GO:0046651	lymphocyte proliferation	83/1801	177/8135	2.12	1.60e-13	1.33e-11	177
GO:0002696	GO:0002696	positive regulation of leukocyte activation	91/1801	202/8135	2.03	2.06e-13	1.67e-11	202
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	73/1801	149/8135	2.21	3.08e-13	2.45e-11	149
GO:0022407	GO:0022407	regulation of cell-cell adhesion	108/1801	260/8135	1.88	8.11e-13	6.33e-11	260
GO:0030155	GO:0030155	regulation of cell adhesion	155/1801	419/8135	1.67	9.10e-13	6.96e-11	419
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	108/1801	261/8135	1.87	1.09e-12	8.18e-11	261
GO:0050867	GO:0050867	positive regulation of cell activation	92/1801	210/8135	1.98	1.13e-12	8.29e-11	210
GO:0071346	GO:0071346	cellular response to interferon-gamma	59/1801	112/8135	2.38	1.17e-12	8.46e-11	112
GO:0032609	GO:0032609	interferon-gamma production	50/1801	88/8135	2.57	1.42e-12	1.01e-10	88
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	81/1801	177/8135	2.07	1.61e-12	1.12e-10	177
GO:0002819	GO:0002819	regulation of adaptive immune response	56/1801	105/8135	2.41	2.26e-12	1.55e-10	105
GO:0070663	GO:0070663	regulation of leukocyte proliferation	74/1801	158/8135	2.12	3.67e-12	2.47e-10	158
GO:0009617	GO:0009617	response to bacterium	147/1801	398/8135	1.67	4.25e-12	2.81e-10	398
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	37/1801	57/8135	2.93	4.56e-12	2.96e-10	57
GO:0032479	GO:0032479	regulation of type I interferon production	29/1801	39/8135	3.36	5.08e-12	3.20e-10	39
GO:0032606	GO:0032606	type I interferon production	29/1801	39/8135	3.36	5.08e-12	3.20e-10	39
GO:0046631	GO:0046631	alpha-beta T cell activation	51/1801	93/8135	2.48	5.40e-12	3.34e-10	93
GO:0001819	GO:0001819	positive regulation of cytokine production	109/1801	271/8135	1.82	7.40e-12	4.51e-10	271
GO:0045089	GO:0045089	positive regulation of innate immune response	77/1801	169/8135	2.06	7.58e-12	4.55e-10	169
GO:0030217	GO:0030217	T cell differentiation	71/1801	151/8135	2.12	8.02e-12	4.74e-10	151
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	106/1801	262/8135	1.83	9.49e-12	5.52e-10	262
GO:0031349	GO:0031349	positive regulation of defense response	104/1801	257/8135	1.83	1.48e-11	8.47e-10	257
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	51/1801	95/8135	2.42	1.58e-11	8.92e-10	95
GO:0043299	GO:0043299	leukocyte degranulation	103/1801	254/8135	1.83	1.60e-11	8.92e-10	254
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	70/1801	151/8135	2.09	2.57e-11	1.41e-09	151
GO:0002699	GO:0002699	positive regulation of immune effector process	66/1801	140/8135	2.13	3.81e-11	2.06e-09	140
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	69/1801	150/8135	2.08	5.53e-11	2.95e-09	150
GO:0045785	GO:0045785	positive regulation of cell adhesion	104/1801	262/8135	1.79	5.77e-11	3.04e-09	262
GO:0036230	GO:0036230	granulocyte activation	95/1801	233/8135	1.84	7.04e-11	3.66e-09	233
GO:0002446	GO:0002446	neutrophil mediated immunity	93/1801	227/8135	1.85	8.21e-11	4.21e-09	227
GO:0042113	GO:0042113	B cell activation	63/1801	134/8135	2.12	1.23e-10	6.22e-09	134
GO:0002283	GO:0002283	neutrophil activation involved in immune response	91/1801	222/8135	1.85	1.27e-10	6.37e-09	222
GO:0032649	GO:0032649	regulation of interferon-gamma production	44/1801	80/8135	2.48	1.37e-10	6.70e-09	80
GO:0050852	GO:0050852	T cell receptor signaling pathway	44/1801	80/8135	2.48	1.37e-10	6.70e-09	80
GO:0035456	GO:0035456	response to interferon-beta	15/1801	15/8135	4.52	1.44e-10	6.92e-09	15
GO:1902105	GO:1902105	regulation of leukocyte differentiation	76/1801	175/8135	1.96	1.79e-10	8.52e-09	175
GO:0042119	GO:0042119	neutrophil activation	93/1801	230/8135	1.83	1.92e-10	9.01e-09	230
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	62/1801	133/8135	2.11	2.68e-10	1.24e-08	133
GO:0043312	GO:0043312	neutrophil degranulation	89/1801	219/8135	1.84	3.49e-10	1.60e-08	219
GO:0002821	GO:0002821	positive regulation of adaptive immune response	39/1801	69/8135	2.55	5.21e-10	2.36e-08	69
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	35/1801	59/8135	2.68	6.66e-10	2.99e-08	59
GO:0002474	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	17/1801	19/8135	4.04	7.47e-10	3.31e-08	19
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	51/1801	104/8135	2.22	1.14e-09	5.02e-08	104
GO:0032103	GO:0032103	positive regulation of response to external stimulus	84/1801	208/8135	1.82	1.59e-09	6.87e-08	208
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	15/1801	16/8135	4.23	1.83e-09	7.82e-08	16
GO:0042098	GO:0042098	T cell proliferation	56/1801	120/8135	2.11	1.87e-09	7.93e-08	120
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	32/1801	53/8135	2.73	1.94e-09	8.14e-08	53
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	37/1801	66/8135	2.53	1.98e-09	8.23e-08	66
GO:0002218	GO:0002218	activation of innate immune response	59/1801	130/8135	2.05	2.63e-09	1.08e-07	130
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	57/1801	125/8135	2.06	3.93e-09	1.60e-07	125
GO:0031295	GO:0031295	T cell costimulation	25/1801	37/8135	3.05	4.08e-09	1.64e-07	37
GO:0042129	GO:0042129	regulation of T cell proliferation	51/1801	108/8135	2.13	5.99e-09	2.38e-07	108
GO:0050900	GO:0050900	leukocyte migration	111/1801	306/8135	1.64	6.70e-09	2.64e-07	306
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	35/1801	63/8135	2.51	7.50e-09	2.92e-07	63
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	58/1801	130/8135	2.02	7.85e-09	3.03e-07	130
GO:0016032	GO:0016032	viral process	83/1801	211/8135	1.78	8.62e-09	3.30e-07	211
GO:0031294	GO:0031294	lymphocyte costimulation	25/1801	38/8135	2.97	9.41e-09	3.56e-07	38
GO:0042100	GO:0042100	B cell proliferation	34/1801	61/8135	2.52	1.10e-08	4.12e-07	61
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	47/1801	98/8135	2.17	1.27e-08	4.73e-07	98
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	12/1801	12/8135	4.52	1.35e-08	4.96e-07	12
GO:0071216	GO:0071216	cellular response to biotic stimulus	59/1801	135/8135	1.97	1.49e-08	5.44e-07	135
GO:0002831	GO:0002831	regulation of response to biotic stimulus	36/1801	67/8135	2.43	1.51e-08	5.47e-07	67
GO:1903901	GO:1903901	negative regulation of viral life cycle	25/1801	39/8135	2.90	2.07e-08	7.41e-07	39
GO:0042102	GO:0042102	positive regulation of T cell proliferation	39/1801	76/8135	2.32	2.10e-08	7.43e-07	76
GO:0002440	GO:0002440	production of molecular mediator of immune response	52/1801	115/8135	2.04	2.69e-08	9.44e-07	115
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	49/1801	106/8135	2.09	2.82e-08	9.71e-07	106
GO:0019724	GO:0019724	B cell mediated immunity	37/1801	71/8135	2.35	2.83e-08	9.71e-07	71
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	48/1801	103/8135	2.10	2.84e-08	9.71e-07	103
GO:0050727	GO:0050727	regulation of inflammatory response	93/1801	251/8135	1.67	3.61e-08	1.22e-06	251
GO:0032655	GO:0032655	regulation of interleukin-12 production	23/1801	35/8135	2.97	3.86e-08	1.30e-06	35
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	14/1801	16/8135	3.95	4.95e-08	1.65e-06	16
GO:0045071	GO:0045071	negative regulation of viral genome replication	22/1801	33/8135	3.01	5.18e-08	1.71e-06	33
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	34/1801	64/8135	2.40	5.54e-08	1.81e-06	64
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	49/1801	108/8135	2.05	5.92e-08	1.92e-06	108
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	47/1801	102/8135	2.08	6.12e-08	1.97e-06	102
GO:0016064	GO:0016064	immunoglobulin mediated immune response	36/1801	70/8135	2.32	6.80e-08	2.16e-06	70
GO:0046632	GO:0046632	alpha-beta T cell differentiation	36/1801	70/8135	2.32	6.80e-08	2.16e-06	70
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	21/1801	31/8135	3.06	6.88e-08	2.16e-06	31
GO:0032615	GO:0032615	interleukin-12 production	23/1801	36/8135	2.89	8.45e-08	2.64e-06	36
GO:0045069	GO:0045069	regulation of viral genome replication	25/1801	41/8135	2.75	8.85e-08	2.73e-06	41
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	30/1801	54/8135	2.51	8.90e-08	2.73e-06	54
GO:0030595	GO:0030595	leukocyte chemotaxis	68/1801	170/8135	1.81	9.01e-08	2.74e-06	170
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	43/1801	91/8135	2.13	9.08e-08	2.74e-06	91
GO:0044403	GO:0044403	symbiont process	90/1801	245/8135	1.66	9.55e-08	2.86e-06	245
GO:0002758	GO:0002758	innate immune response-activating signal transduction	54/1801	125/8135	1.95	9.77e-08	2.91e-06	125
GO:0002673	GO:0002673	regulation of acute inflammatory response	37/1801	74/8135	2.26	1.16e-07	3.42e-06	74
GO:0002685	GO:0002685	regulation of leukocyte migration	56/1801	132/8135	1.92	1.20e-07	3.53e-06	132
GO:0043065	GO:0043065	positive regulation of apoptotic process	101/1801	285/8135	1.60	1.25e-07	3.65e-06	285
GO:0001818	GO:0001818	negative regulation of cytokine production	66/1801	165/8135	1.81	1.39e-07	4.02e-06	165
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	35/1801	69/8135	2.29	1.61e-07	4.62e-06	69
GO:0032496	GO:0032496	response to lipopolysaccharide	80/1801	213/8135	1.70	1.70e-07	4.80e-06	213
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	49/1801	111/8135	1.99	1.70e-07	4.80e-06	111
GO:0002695	GO:0002695	negative regulation of leukocyte activation	48/1801	108/8135	2.01	1.76e-07	4.94e-06	108
GO:0043068	GO:0043068	positive regulation of programmed cell death	101/1801	287/8135	1.59	1.85e-07	5.16e-06	287
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	39/1801	81/8135	2.17	1.93e-07	5.33e-06	81
GO:0010942	GO:0010942	positive regulation of cell death	110/1801	320/8135	1.55	2.10e-07	5.77e-06	320
GO:0060326	GO:0060326	cell chemotaxis	82/1801	221/8135	1.68	2.18e-07	5.95e-06	221
GO:0002286	GO:0002286	T cell activation involved in immune response	33/1801	64/8135	2.33	2.21e-07	5.98e-06	64
GO:0032480	GO:0032480	negative regulation of type I interferon production	14/1801	17/8135	3.72	2.23e-07	6.00e-06	17
GO:0002237	GO:0002237	response to molecule of bacterial origin	82/1801	222/8135	1.67	2.72e-07	7.28e-06	222
GO:0035458	GO:0035458	cellular response to interferon-beta	10/1801	10/8135	4.52	2.77e-07	7.36e-06	10
GO:0002526	GO:0002526	acute inflammatory response	51/1801	119/8135	1.94	2.99e-07	7.89e-06	119
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	25/1801	43/8135	2.63	3.26e-07	8.49e-06	43
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	25/1801	43/8135	2.63	3.26e-07	8.49e-06	43
GO:0050688	GO:0050688	regulation of defense response to virus	21/1801	33/8135	2.87	3.45e-07	8.91e-06	33
GO:1903706	GO:1903706	regulation of hemopoiesis	87/1801	241/8135	1.63	3.80e-07	9.68e-06	241
GO:0044419	GO:0044419	interspecies interaction between organisms	96/1801	273/8135	1.59	3.90e-07	9.87e-06	273
GO:0050920	GO:0050920	regulation of chemotaxis	59/1801	146/8135	1.83	4.23e-07	1.06e-05	146
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	41/1801	89/8135	2.08	4.27e-07	1.07e-05	89
GO:0050853	GO:0050853	B cell receptor signaling pathway	22/1801	36/8135	2.76	5.04e-07	1.25e-05	36
GO:0006959	GO:0006959	humoral immune response	71/1801	187/8135	1.71	5.20e-07	1.28e-05	187
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	11/1801	12/8135	4.14	5.86e-07	1.42e-05	12
GO:0035455	GO:0035455	response to interferon-alpha	11/1801	12/8135	4.14	5.86e-07	1.42e-05	12
GO:0098586	GO:0098586	cellular response to virus	16/1801	22/8135	3.29	5.89e-07	1.42e-05	22
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	25/1801	44/8135	2.57	5.98e-07	1.43e-05	44
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	41/1801	90/8135	2.06	6.19e-07	1.46e-05	90
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	41/1801	90/8135	2.06	6.19e-07	1.46e-05	90
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	36/1801	75/8135	2.17	6.23e-07	1.46e-05	75
GO:1903900	GO:1903900	regulation of viral life cycle	30/1801	58/8135	2.34	7.18e-07	1.67e-05	58
GO:0048525	GO:0048525	negative regulation of viral process	26/1801	47/8135	2.50	7.24e-07	1.67e-05	47
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	31/1801	61/8135	2.30	7.78e-07	1.78e-05	61
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	39/1801	85/8135	2.07	9.25e-07	2.11e-05	85
GO:0050866	GO:0050866	negative regulation of cell activation	51/1801	123/8135	1.87	1.02e-06	2.31e-05	123
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	31/1801	62/8135	2.26	1.23e-06	2.75e-05	62
GO:0045580	GO:0045580	regulation of T cell differentiation	40/1801	89/8135	2.03	1.30e-06	2.90e-05	89
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	39/1801	86/8135	2.05	1.34e-06	2.96e-05	86
GO:0019079	GO:0019079	viral genome replication	27/1801	51/8135	2.39	1.42e-06	3.13e-05	51
GO:0032481	GO:0032481	positive regulation of type I interferon production	16/1801	23/8135	3.14	1.54e-06	3.35e-05	23
GO:0046633	GO:0046633	alpha-beta T cell proliferation	16/1801	23/8135	3.14	1.54e-06	3.35e-05	23
GO:0030888	GO:0030888	regulation of B cell proliferation	25/1801	46/8135	2.45	1.84e-06	3.97e-05	46
GO:0050663	GO:0050663	cytokine secretion	57/1801	145/8135	1.78	1.91e-06	4.09e-05	145
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	35/1801	75/8135	2.11	2.04e-06	4.36e-05	75
GO:0031343	GO:0031343	positive regulation of cell killing	26/1801	49/8135	2.40	2.10e-06	4.46e-05	49
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	27/1801	52/8135	2.35	2.34e-06	4.90e-05	52
GO:0051767	GO:0051767	nitric-oxide synthase biosynthetic process	10/1801	11/8135	4.11	2.44e-06	5.06e-05	11
GO:0051769	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	10/1801	11/8135	4.11	2.44e-06	5.06e-05	11
GO:0043901	GO:0043901	negative regulation of multi-organism process	40/1801	91/8135	1.99	2.60e-06	5.37e-05	91
GO:0045058	GO:0045058	T cell selection	21/1801	36/8135	2.63	2.69e-06	5.52e-05	36
GO:0050792	GO:0050792	regulation of viral process	33/1801	70/8135	2.13	3.02e-06	6.16e-05	70
GO:0051271	GO:0051271	negative regulation of cellular component movement	67/1801	181/8135	1.67	3.07e-06	6.20e-05	181
GO:0002577	GO:0002577	regulation of antigen processing and presentation	12/1801	15/8135	3.61	3.10e-06	6.20e-05	15
GO:0032607	GO:0032607	interferon-alpha production	12/1801	15/8135	3.61	3.10e-06	6.20e-05	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	12/1801	15/8135	3.61	3.10e-06	6.20e-05	15
GO:0097529	GO:0097529	myeloid leukocyte migration	59/1801	154/8135	1.73	3.37e-06	6.71e-05	154
GO:0032640	GO:0032640	tumor necrosis factor production	38/1801	86/8135	2.00	3.96e-06	7.80e-05	86
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	38/1801	86/8135	2.00	3.96e-06	7.80e-05	86
GO:0031341	GO:0031341	regulation of cell killing	32/1801	68/8135	2.13	4.46e-06	8.67e-05	68
GO:0071887	GO:0071887	leukocyte apoptotic process	32/1801	68/8135	2.13	4.46e-06	8.67e-05	68
GO:0007162	GO:0007162	negative regulation of cell adhesion	61/1801	162/8135	1.70	4.47e-06	8.67e-05	162
GO:0040013	GO:0040013	negative regulation of locomotion	67/1801	183/8135	1.65	4.76e-06	9.19e-05	183
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	49/1801	122/8135	1.81	4.90e-06	9.40e-05	122
GO:0002573	GO:0002573	myeloid leukocyte differentiation	51/1801	129/8135	1.79	5.42e-06	1.04e-04	129
GO:0030449	GO:0030449	regulation of complement activation	22/1801	40/8135	2.48	5.92e-06	1.13e-04	40
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	29/1801	60/8135	2.18	6.43e-06	1.22e-04	60
GO:0050864	GO:0050864	regulation of B cell activation	33/1801	72/8135	2.07	6.49e-06	1.22e-04	72
GO:0051090	GO:0051090	regulation of DNA-binding transcription factor activity	70/1801	195/8135	1.62	6.52e-06	1.22e-04	195
GO:0002224	GO:0002224	toll-like receptor signaling pathway	32/1801	69/8135	2.09	6.57e-06	1.23e-04	69
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	16/1801	25/8135	2.89	8.08e-06	1.50e-04	25
GO:0032102	GO:0032102	negative regulation of response to external stimulus	73/1801	207/8135	1.59	8.60e-06	1.59e-04	207
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	21/1801	38/8135	2.50	8.73e-06	1.60e-04	38
GO:0002456	GO:0002456	T cell mediated immunity	32/1801	70/8135	2.06	9.56e-06	1.75e-04	70
GO:0030183	GO:0030183	B cell differentiation	31/1801	67/8135	2.09	9.69e-06	1.76e-04	67
GO:0050868	GO:0050868	negative regulation of T cell activation	31/1801	67/8135	2.09	9.69e-06	1.76e-04	67
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	30/1801	64/8135	2.12	9.74e-06	1.76e-04	64
GO:0050921	GO:0050921	positive regulation of chemotaxis	39/1801	92/8135	1.91	1.00e-05	1.80e-04	92
GO:0002483	GO:0002483	antigen processing and presentation of endogenous peptide antigen	9/1801	10/8135	4.07	1.01e-05	1.80e-04	10
GO:2000257	GO:2000257	regulation of protein activation cascade	22/1801	41/8135	2.42	1.01e-05	1.80e-04	41
GO:0050777	GO:0050777	negative regulation of immune response	38/1801	89/8135	1.93	1.06e-05	1.88e-04	89
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	42/1801	102/8135	1.86	1.11e-05	1.96e-04	102
GO:0002709	GO:0002709	regulation of T cell mediated immunity	24/1801	47/8135	2.31	1.23e-05	2.17e-04	47
GO:0050707	GO:0050707	regulation of cytokine secretion	50/1801	129/8135	1.75	1.28e-05	2.23e-04	129
GO:0042089	GO:0042089	cytokine biosynthetic process	34/1801	77/8135	1.99	1.29e-05	2.24e-04	77
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	25/1801	50/8135	2.26	1.31e-05	2.28e-04	50
GO:0043900	GO:0043900	regulation of multi-organism process	67/1801	188/8135	1.61	1.35e-05	2.33e-04	188
GO:0002920	GO:0002920	regulation of humoral immune response	27/1801	56/8135	2.18	1.41e-05	2.43e-04	56
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	28/1801	59/8135	2.14	1.43e-05	2.45e-04	59
GO:0001773	GO:0001773	myeloid dendritic cell activation	14/1801	21/8135	3.01	1.53e-05	2.59e-04	21
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	14/1801	21/8135	3.01	1.53e-05	2.59e-04	21
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	41/1801	100/8135	1.85	1.59e-05	2.69e-04	100
GO:0043368	GO:0043368	positive T cell selection	16/1801	26/8135	2.78	1.67e-05	2.81e-04	26
GO:0045807	GO:0045807	positive regulation of endocytosis	35/1801	81/8135	1.95	1.72e-05	2.87e-04	81
GO:0042107	GO:0042107	cytokine metabolic process	34/1801	78/8135	1.97	1.80e-05	3.00e-04	78
GO:0002686	GO:0002686	negative regulation of leukocyte migration	19/1801	34/8135	2.52	1.90e-05	3.15e-04	34
GO:0002698	GO:0002698	negative regulation of immune effector process	31/1801	69/8135	2.03	2.02e-05	3.32e-04	69
GO:0002377	GO:0002377	immunoglobulin production	25/1801	51/8135	2.21	2.04e-05	3.32e-04	51
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	13/1801	19/8135	3.09	2.05e-05	3.32e-04	19
GO:0002753	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	13/1801	19/8135	3.09	2.05e-05	3.32e-04	19
GO:0002755	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/1801	19/8135	3.09	2.05e-05	3.32e-04	19
GO:0032613	GO:0032613	interleukin-10 production	20/1801	37/8135	2.44	2.22e-05	3.58e-04	37
GO:0030336	GO:0030336	negative regulation of cell migration	56/1801	152/8135	1.66	2.29e-05	3.68e-04	152
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	15/1801	24/8135	2.82	2.37e-05	3.79e-04	24
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	34/1801	79/8135	1.94	2.50e-05	3.96e-04	79
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	21/1801	40/8135	2.37	2.50e-05	3.96e-04	40
GO:0032608	GO:0032608	interferon-beta production	12/1801	17/8135	3.19	2.69e-05	4.21e-04	17
GO:0032648	GO:0032648	regulation of interferon-beta production	12/1801	17/8135	3.19	2.69e-05	4.21e-04	17
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	12/1801	17/8135	3.19	2.69e-05	4.21e-04	17
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	18/1801	32/8135	2.54	2.79e-05	4.35e-04	32
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	31/1801	70/8135	2.00	2.86e-05	4.43e-04	70
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	31/1801	70/8135	2.00	2.86e-05	4.43e-04	70
GO:0019058	GO:0019058	viral life cycle	46/1801	119/8135	1.75	3.04e-05	4.69e-04	119
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	26/1801	55/8135	2.14	3.15e-05	4.83e-04	55
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	39/1801	96/8135	1.84	3.27e-05	5.00e-04	96
GO:0050702	GO:0050702	interleukin-1 beta secretion	19/1801	35/8135	2.45	3.29e-05	5.01e-04	35
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	14/1801	22/8135	2.87	3.35e-05	5.06e-04	22
GO:0050691	GO:0050691	regulation of defense response to virus by host	14/1801	22/8135	2.87	3.35e-05	5.06e-04	22
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	11/1801	15/8135	3.31	3.39e-05	5.11e-04	15
GO:2000146	GO:2000146	negative regulation of cell motility	58/1801	161/8135	1.63	3.52e-05	5.29e-04	161
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	10/1801	13/8135	3.47	4.06e-05	6.02e-04	13
GO:0032623	GO:0032623	interleukin-2 production	21/1801	41/8135	2.31	4.06e-05	6.02e-04	41
GO:0050701	GO:0050701	interleukin-1 secretion	21/1801	41/8135	2.31	4.06e-05	6.02e-04	41
GO:0002687	GO:0002687	positive regulation of leukocyte migration	36/1801	87/8135	1.87	4.08e-05	6.03e-04	87
GO:0042088	GO:0042088	T-helper 1 type immune response	17/1801	30/8135	2.56	4.11e-05	6.05e-04	30
GO:0002367	GO:0002367	cytokine production involved in immune response	29/1801	65/8135	2.02	4.35e-05	6.38e-04	65
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	9/1801	11/8135	3.70	4.45e-05	6.49e-04	11
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	23/1801	47/8135	2.21	4.51e-05	6.54e-04	47
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	23/1801	47/8135	2.21	4.51e-05	6.54e-04	47
GO:0030101	GO:0030101	natural killer cell activation	24/1801	50/8135	2.17	4.62e-05	6.67e-04	50
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	34/1801	81/8135	1.90	4.67e-05	6.72e-04	81
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	18/1801	33/8135	2.46	4.88e-05	6.99e-04	33
GO:0048872	GO:0048872	homeostasis of number of cells	48/1801	128/8135	1.69	5.15e-05	7.35e-04	128
GO:0070613	GO:0070613	regulation of protein processing	32/1801	75/8135	1.93	5.28e-05	7.51e-04	75
GO:0001913	GO:0001913	T cell mediated cytotoxicity	19/1801	36/8135	2.38	5.53e-05	7.81e-04	36
GO:0032653	GO:0032653	regulation of interleukin-10 production	19/1801	36/8135	2.38	5.53e-05	7.81e-04	36
GO:0006958	GO:0006958	complement activation, classical pathway	16/1801	28/8135	2.58	6.05e-05	8.49e-04	28
GO:0014015	GO:0014015	positive regulation of gliogenesis	20/1801	39/8135	2.32	6.05e-05	8.49e-04	39
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	12/1801	18/8135	3.01	6.43e-05	8.96e-04	18
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	12/1801	18/8135	3.01	6.43e-05	8.96e-04	18
GO:0001776	GO:0001776	leukocyte homeostasis	27/1801	60/8135	2.03	6.60e-05	9.16e-04	60
GO:0006909	GO:0006909	phagocytosis	47/1801	126/8135	1.68	7.15e-05	9.89e-04	126
GO:1903317	GO:1903317	regulation of protein maturation	32/1801	76/8135	1.90	7.21e-05	9.93e-04	76
GO:0045926	GO:0045926	negative regulation of growth	53/1801	147/8135	1.63	7.37e-05	1.01e-03	147
GO:0001906	GO:0001906	cell killing	41/1801	106/8135	1.75	7.95e-05	1.09e-03	106
GO:1903708	GO:1903708	positive regulation of hemopoiesis	43/1801	113/8135	1.72	8.40e-05	1.15e-03	113
GO:0050729	GO:0050729	positive regulation of inflammatory response	39/1801	100/8135	1.76	9.55e-05	1.29e-03	100
GO:0010596	GO:0010596	negative regulation of endothelial cell migration	13/1801	21/8135	2.80	9.78e-05	1.32e-03	21
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	13/1801	21/8135	2.80	9.78e-05	1.32e-03	21
GO:0045861	GO:0045861	negative regulation of proteolysis	69/1801	206/8135	1.51	9.85e-05	1.32e-03	206
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	24/1801	52/8135	2.08	1.02e-04	1.36e-03	52
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	16/1801	29/8135	2.49	1.07e-04	1.43e-03	29
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	10/1801	14/8135	3.23	1.14e-04	1.51e-03	14
GO:0032612	GO:0032612	interleukin-1 production	28/1801	65/8135	1.95	1.25e-04	1.65e-03	65
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	14/1801	24/8135	2.63	1.30e-04	1.71e-03	24
GO:1902622	GO:1902622	regulation of neutrophil migration	14/1801	24/8135	2.63	1.30e-04	1.71e-03	24
GO:0050856	GO:0050856	regulation of T cell receptor signaling pathway	12/1801	19/8135	2.85	1.39e-04	1.82e-03	19
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	31/1801	75/8135	1.87	1.41e-04	1.83e-03	75
GO:0032728	GO:0032728	positive regulation of interferon-beta production	9/1801	12/8135	3.39	1.43e-04	1.86e-03	12
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	20/1801	41/8135	2.20	1.49e-04	1.93e-03	41
GO:0002292	GO:0002292	T cell differentiation involved in immune response	21/1801	44/8135	2.16	1.52e-04	1.96e-03	44
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	15/1801	27/8135	2.51	1.59e-04	2.05e-03	27
GO:0030889	GO:0030889	negative regulation of B cell proliferation	8/1801	10/8135	3.61	1.66e-04	2.11e-03	10
GO:0032727	GO:0032727	positive regulation of interferon-alpha production	8/1801	10/8135	3.61	1.66e-04	2.11e-03	10
GO:0045078	GO:0045078	positive regulation of interferon-gamma biosynthetic process	8/1801	10/8135	3.61	1.66e-04	2.11e-03	10
GO:0072376	GO:0072376	protein activation cascade	31/1801	76/8135	1.84	1.88e-04	2.39e-03	76
GO:0002828	GO:0002828	regulation of type 2 immune response	13/1801	22/8135	2.67	1.91e-04	2.40e-03	22
GO:0032660	GO:0032660	regulation of interleukin-17 production	13/1801	22/8135	2.67	1.91e-04	2.40e-03	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	13/1801	22/8135	2.67	1.91e-04	2.40e-03	22
GO:0071621	GO:0071621	granulocyte chemotaxis	39/1801	103/8135	1.71	2.00e-04	2.50e-03	103
GO:0031348	GO:0031348	negative regulation of defense response	43/1801	117/8135	1.66	2.10e-04	2.62e-03	117
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	33/1801	83/8135	1.80	2.10e-04	2.62e-03	83
GO:0050764	GO:0050764	regulation of phagocytosis	23/1801	51/8135	2.04	2.17e-04	2.70e-03	51
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	19/1801	39/8135	2.20	2.22e-04	2.73e-03	39
GO:0050766	GO:0050766	positive regulation of phagocytosis	19/1801	39/8135	2.20	2.22e-04	2.73e-03	39
GO:0010951	GO:0010951	negative regulation of endopeptidase activity	57/1801	167/8135	1.54	2.22e-04	2.73e-03	167
GO:0033077	GO:0033077	T cell differentiation in thymus	20/1801	42/8135	2.15	2.26e-04	2.76e-03	42
GO:0043154	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	20/1801	42/8135	2.15	2.26e-04	2.76e-03	42
GO:0030593	GO:0030593	neutrophil chemotaxis	35/1801	90/8135	1.76	2.29e-04	2.79e-03	90
GO:0010466	GO:0010466	negative regulation of peptidase activity	59/1801	175/8135	1.52	2.53e-04	3.07e-03	175
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	26/1801	61/8135	1.93	2.65e-04	3.21e-03	61
GO:0042095	GO:0042095	interferon-gamma biosynthetic process	10/1801	15/8135	3.01	2.74e-04	3.29e-03	15
GO:0045061	GO:0045061	thymic T cell selection	10/1801	15/8135	3.01	2.74e-04	3.29e-03	15
GO:1902624	GO:1902624	positive regulation of neutrophil migration	12/1801	20/8135	2.71	2.78e-04	3.34e-03	20
GO:0006956	GO:0006956	complement activation	24/1801	55/8135	1.97	2.95e-04	3.53e-03	55
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	16/1801	31/8135	2.33	3.01e-04	3.58e-03	31
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	17/1801	34/8135	2.26	3.20e-04	3.79e-03	34
GO:0006968	GO:0006968	cellular defense response	22/1801	49/8135	2.03	3.20e-04	3.79e-03	49
GO:0097530	GO:0097530	granulocyte migration	41/1801	112/8135	1.65	3.22e-04	3.79e-03	112
GO:2000117	GO:2000117	negative regulation of cysteine-type endopeptidase activity	21/1801	46/8135	2.06	3.29e-04	3.87e-03	46
GO:0002228	GO:0002228	natural killer cell mediated immunity	20/1801	43/8135	2.10	3.35e-04	3.87e-03	43
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	20/1801	43/8135	2.10	3.35e-04	3.87e-03	43
GO:0072678	GO:0072678	T cell migration	20/1801	43/8135	2.10	3.35e-04	3.87e-03	43
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	19/1801	40/8135	2.15	3.36e-04	3.87e-03	40
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	19/1801	40/8135	2.15	3.36e-04	3.87e-03	40
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	19/1801	40/8135	2.15	3.36e-04	3.87e-03	40
GO:0032620	GO:0032620	interleukin-17 production	13/1801	23/8135	2.55	3.50e-04	4.02e-03	23
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	13/1801	23/8135	2.55	3.50e-04	4.02e-03	23
GO:0016485	GO:0016485	protein processing	51/1801	148/8135	1.56	3.60e-04	4.11e-03	148
GO:0032740	GO:0032740	positive regulation of interleukin-17 production	9/1801	13/8135	3.13	3.73e-04	4.22e-03	13
GO:0051403	GO:0051403	stress-activated MAPK cascade	49/1801	141/8135	1.57	3.73e-04	4.22e-03	141
GO:0043542	GO:0043542	endothelial cell migration	37/1801	99/8135	1.69	3.89e-04	4.37e-03	99
GO:0070304	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	37/1801	99/8135	1.69	3.89e-04	4.37e-03	99
GO:2000116	GO:2000116	regulation of cysteine-type endopeptidase activity	41/1801	113/8135	1.64	3.99e-04	4.47e-03	113
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	11/1801	18/8135	2.76	4.05e-04	4.51e-03	18
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	11/1801	18/8135	2.76	4.05e-04	4.51e-03	18
GO:0042092	GO:0042092	type 2 immune response	14/1801	26/8135	2.43	4.08e-04	4.53e-03	26
GO:1990266	GO:1990266	neutrophil migration	36/1801	96/8135	1.69	4.30e-04	4.76e-03	96
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	23/1801	53/8135	1.96	4.33e-04	4.78e-03	53
GO:0050706	GO:0050706	regulation of interleukin-1 beta secretion	15/1801	29/8135	2.34	4.50e-04	4.95e-03	29
GO:0097028	GO:0097028	dendritic cell differentiation	15/1801	29/8135	2.34	4.50e-04	4.95e-03	29
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	30/1801	76/8135	1.78	4.65e-04	5.09e-03	76
GO:0002762	GO:0002762	negative regulation of myeloid leukocyte differentiation	16/1801	32/8135	2.26	4.79e-04	5.19e-03	32
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	16/1801	32/8135	2.26	4.79e-04	5.19e-03	32
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	16/1801	32/8135	2.26	4.79e-04	5.19e-03	32
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	16/1801	32/8135	2.26	4.79e-04	5.19e-03	32
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	20/1801	44/8135	2.05	4.88e-04	5.22e-03	44
GO:0030852	GO:0030852	regulation of granulocyte differentiation	8/1801	11/8135	3.29	4.90e-04	5.22e-03	11
GO:0032695	GO:0032695	negative regulation of interleukin-12 production	8/1801	11/8135	3.29	4.90e-04	5.22e-03	11
GO:0034162	GO:0034162	toll-like receptor 9 signaling pathway	8/1801	11/8135	3.29	4.90e-04	5.22e-03	11
GO:0039528	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	8/1801	11/8135	3.29	4.90e-04	5.22e-03	11
GO:0043374	GO:0043374	CD8-positive, alpha-beta T cell differentiation	8/1801	11/8135	3.29	4.90e-04	5.22e-03	11
GO:0032663	GO:0032663	regulation of interleukin-2 production	17/1801	35/8135	2.19	4.95e-04	5.24e-03	35
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	17/1801	35/8135	2.19	4.95e-04	5.24e-03	35
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	18/1801	38/8135	2.14	5.00e-04	5.28e-03	38
GO:0032652	GO:0032652	regulation of interleukin-1 production	24/1801	57/8135	1.90	5.61e-04	5.87e-03	57
GO:0045582	GO:0045582	positive regulation of T cell differentiation	24/1801	57/8135	1.90	5.61e-04	5.87e-03	57
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	10/1801	16/8135	2.82	5.85e-04	6.08e-03	16
GO:1903010	GO:1903010	regulation of bone development	10/1801	16/8135	2.82	5.85e-04	6.08e-03	16
GO:0032611	GO:0032611	interleukin-1 beta production	23/1801	54/8135	1.92	5.98e-04	6.18e-03	54
GO:0038093	GO:0038093	Fc receptor signaling pathway	23/1801	54/8135	1.92	5.98e-04	6.18e-03	54
GO:0007254	GO:0007254	JNK cascade	41/1801	115/8135	1.61	6.05e-04	6.24e-03	115
GO:0032673	GO:0032673	regulation of interleukin-4 production	13/1801	24/8135	2.45	6.10e-04	6.28e-03	24
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	22/1801	51/8135	1.95	6.34e-04	6.48e-03	51
GO:0046330	GO:0046330	positive regulation of JNK cascade	32/1801	84/8135	1.72	6.39e-04	6.53e-03	84
GO:0030193	GO:0030193	regulation of blood coagulation	26/1801	64/8135	1.84	6.52e-04	6.62e-03	64
GO:1900046	GO:1900046	regulation of hemostasis	26/1801	64/8135	1.84	6.52e-04	6.62e-03	64
GO:0032874	GO:0032874	positive regulation of stress-activated MAPK cascade	36/1801	98/8135	1.66	6.76e-04	6.82e-03	98
GO:0045824	GO:0045824	negative regulation of innate immune response	14/1801	27/8135	2.34	6.76e-04	6.82e-03	27
GO:0046328	GO:0046328	regulation of JNK cascade	38/1801	105/8135	1.63	6.79e-04	6.84e-03	105
GO:0032637	GO:0032637	interleukin-8 production	20/1801	45/8135	2.01	6.97e-04	7.01e-03	45
GO:0010633	GO:0010633	negative regulation of epithelial cell migration	15/1801	30/8135	2.26	7.18e-04	7.18e-03	30
GO:0050922	GO:0050922	negative regulation of chemotaxis	19/1801	42/8135	2.04	7.22e-04	7.20e-03	42
GO:0031098	GO:0031098	stress-activated protein kinase signaling cascade	51/1801	152/8135	1.52	7.31e-04	7.25e-03	152
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	18/1801	39/8135	2.08	7.39e-04	7.31e-03	39
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	17/1801	36/8135	2.13	7.46e-04	7.35e-03	36
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	23/1801	55/8135	1.89	8.15e-04	8.01e-03	55
GO:0045072	GO:0045072	regulation of interferon-gamma biosynthetic process	9/1801	14/8135	2.90	8.38e-04	8.19e-03	14
GO:0030100	GO:0030100	regulation of endocytosis	45/1801	131/8135	1.55	8.41e-04	8.20e-03	131
GO:0010594	GO:0010594	regulation of endothelial cell migration	29/1801	75/8135	1.75	8.53e-04	8.30e-03	75
GO:0050818	GO:0050818	regulation of coagulation	26/1801	65/8135	1.81	8.61e-04	8.35e-03	65
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	12/1801	22/8135	2.46	9.14e-04	8.82e-03	22
GO:0050718	GO:0050718	positive regulation of interleukin-1 beta secretion	12/1801	22/8135	2.46	9.14e-04	8.82e-03	22
GO:0002675	GO:0002675	positive regulation of acute inflammatory response	13/1801	25/8135	2.35	1.02e-03	9.72e-03	25
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	13/1801	25/8135	2.35	1.02e-03	9.72e-03	25
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	13/1801	25/8135	2.35	1.02e-03	9.72e-03	25
GO:1903034	GO:1903034	regulation of response to wounding	38/1801	107/8135	1.60	1.03e-03	9.78e-03	107
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	19/1801	43/8135	2.00	1.03e-03	9.78e-03	43
GO:0032677	GO:0032677	regulation of interleukin-8 production	18/1801	40/8135	2.03	1.07e-03	1.01e-02	40
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	18/1801	40/8135	2.03	1.07e-03	1.01e-02	40
GO:0032633	GO:0032633	interleukin-4 production	14/1801	28/8135	2.26	1.08e-03	1.02e-02	28
GO:0019722	GO:0019722	calcium-mediated signaling	49/1801	147/8135	1.51	1.08e-03	1.02e-02	147
GO:0042093	GO:0042093	T-helper cell differentiation	17/1801	37/8135	2.08	1.10e-03	1.03e-02	37
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	17/1801	37/8135	2.08	1.10e-03	1.03e-02	37
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	16/1801	34/8135	2.13	1.11e-03	1.04e-02	34
GO:2000108	GO:2000108	positive regulation of leukocyte apoptotic process	10/1801	17/8135	2.66	1.14e-03	1.06e-02	17
GO:0043281	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	35/1801	97/8135	1.63	1.15e-03	1.07e-02	97
GO:0043537	GO:0043537	negative regulation of blood vessel endothelial cell migration	8/1801	12/8135	3.01	1.18e-03	1.09e-02	12
GO:0045862	GO:0045862	positive regulation of proteolysis	48/1801	144/8135	1.51	1.21e-03	1.11e-02	144
GO:0070302	GO:0070302	regulation of stress-activated protein kinase signaling cascade	43/1801	126/8135	1.54	1.26e-03	1.15e-02	126
GO:0050869	GO:0050869	negative regulation of B cell activation	11/1801	20/8135	2.48	1.37e-03	1.25e-02	20
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	11/1801	20/8135	2.48	1.37e-03	1.25e-02	20
GO:0032635	GO:0032635	interleukin-6 production	33/1801	91/8135	1.64	1.43e-03	1.30e-02	91
GO:0002260	GO:0002260	lymphocyte homeostasis	19/1801	44/8135	1.95	1.44e-03	1.30e-02	44
GO:0034113	GO:0034113	heterotypic cell-cell adhesion	19/1801	44/8135	1.95	1.44e-03	1.30e-02	44
GO:0045670	GO:0045670	regulation of osteoclast differentiation	19/1801	44/8135	1.95	1.44e-03	1.30e-02	44
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	12/1801	23/8135	2.36	1.53e-03	1.36e-02	23
GO:0014009	GO:0014009	glial cell proliferation	12/1801	23/8135	2.36	1.53e-03	1.36e-02	23
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	17/1801	38/8135	2.02	1.58e-03	1.41e-02	38
GO:2000401	GO:2000401	regulation of lymphocyte migration	17/1801	38/8135	2.02	1.58e-03	1.41e-02	38
GO:0050716	GO:0050716	positive regulation of interleukin-1 secretion	13/1801	26/8135	2.26	1.62e-03	1.43e-02	26
GO:0002418	GO:0002418	immune response to tumor cell	7/1801	10/8135	3.16	1.63e-03	1.43e-02	10
GO:0045063	GO:0045063	T-helper 1 cell differentiation	7/1801	10/8135	3.16	1.63e-03	1.43e-02	10
GO:0060252	GO:0060252	positive regulation of glial cell proliferation	7/1801	10/8135	3.16	1.63e-03	1.43e-02	10
GO:1903587	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	7/1801	10/8135	3.16	1.63e-03	1.43e-02	10
GO:2001185	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	7/1801	10/8135	3.16	1.63e-03	1.43e-02	10
GO:0042130	GO:0042130	negative regulation of T cell proliferation	16/1801	35/8135	2.06	1.64e-03	1.43e-02	35
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	15/1801	32/8135	2.12	1.67e-03	1.45e-02	32
GO:0002092	GO:0002092	positive regulation of receptor internalization	9/1801	15/8135	2.71	1.68e-03	1.46e-02	15
GO:0042832	GO:0042832	defense response to protozoan	9/1801	15/8135	2.71	1.68e-03	1.46e-02	15
GO:0043243	GO:0043243	positive regulation of protein complex disassembly	9/1801	15/8135	2.71	1.68e-03	1.46e-02	15
GO:0032675	GO:0032675	regulation of interleukin-6 production	31/1801	85/8135	1.65	1.77e-03	1.52e-02	85
GO:0030308	GO:0030308	negative regulation of cell growth	34/1801	96/8135	1.60	1.94e-03	1.66e-02	96
GO:0050715	GO:0050715	positive regulation of cytokine secretion	32/1801	89/8135	1.62	1.97e-03	1.68e-02	89
GO:0045576	GO:0045576	mast cell activation	19/1801	45/8135	1.91	1.98e-03	1.68e-02	45
GO:0050871	GO:0050871	positive regulation of B cell activation	19/1801	45/8135	1.91	1.98e-03	1.68e-02	45
GO:0032872	GO:0032872	regulation of stress-activated MAPK cascade	42/1801	125/8135	1.52	2.00e-03	1.70e-02	125
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	10/1801	18/8135	2.51	2.06e-03	1.72e-02	18
GO:0002832	GO:0002832	negative regulation of response to biotic stimulus	10/1801	18/8135	2.51	2.06e-03	1.72e-02	18
GO:0045577	GO:0045577	regulation of B cell differentiation	10/1801	18/8135	2.51	2.06e-03	1.72e-02	18
GO:0002040	GO:0002040	sprouting angiogenesis	25/1801	65/8135	1.74	2.07e-03	1.72e-02	65
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	25/1801	65/8135	1.74	2.07e-03	1.72e-02	65
GO:0061041	GO:0061041	regulation of wound healing	33/1801	93/8135	1.60	2.17e-03	1.80e-02	93
GO:0043534	GO:0043534	blood vessel endothelial cell migration	21/1801	52/8135	1.82	2.29e-03	1.90e-02	52
GO:0032732	GO:0032732	positive regulation of interleukin-1 production	15/1801	33/8135	2.05	2.44e-03	2.00e-02	33
GO:1904705	GO:1904705	regulation of vascular smooth muscle cell proliferation	15/1801	33/8135	2.05	2.44e-03	2.00e-02	33
GO:1990874	GO:1990874	vascular smooth muscle cell proliferation	15/1801	33/8135	2.05	2.44e-03	2.00e-02	33
GO:0050858	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	8/1801	13/8135	2.78	2.48e-03	2.03e-02	13
GO:2000484	GO:2000484	positive regulation of interleukin-8 secretion	8/1801	13/8135	2.78	2.48e-03	2.03e-02	13
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	13/1801	27/8135	2.17	2.50e-03	2.03e-02	27
GO:2000404	GO:2000404	regulation of T cell migration	13/1801	27/8135	2.17	2.50e-03	2.03e-02	27
GO:0032651	GO:0032651	regulation of interleukin-1 beta production	19/1801	46/8135	1.87	2.69e-03	2.18e-02	46
GO:0072676	GO:0072676	lymphocyte migration	29/1801	80/8135	1.64	2.73e-03	2.20e-02	80
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	24/1801	63/8135	1.72	2.92e-03	2.34e-02	63
GO:0016525	GO:0016525	negative regulation of angiogenesis	24/1801	63/8135	1.72	2.92e-03	2.34e-02	63
GO:0007259	GO:0007259	JAK-STAT cascade	30/1801	84/8135	1.61	3.02e-03	2.41e-02	84
GO:0001562	GO:0001562	response to protozoan	9/1801	16/8135	2.54	3.10e-03	2.46e-02	16
GO:0042454	GO:0042454	ribonucleoside catabolic process	9/1801	16/8135	2.54	3.10e-03	2.46e-02	16
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	9/1801	16/8135	2.54	3.10e-03	2.46e-02	16
GO:0002312	GO:0002312	B cell activation involved in immune response	17/1801	40/8135	1.92	3.10e-03	2.46e-02	40
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	17/1801	40/8135	1.92	3.10e-03	2.46e-02	40
GO:0097696	GO:0097696	STAT cascade	31/1801	88/8135	1.59	3.30e-03	2.61e-02	88
GO:0048640	GO:0048640	negative regulation of developmental growth	25/1801	67/8135	1.69	3.34e-03	2.63e-02	67
GO:0001782	GO:0001782	B cell homeostasis	10/1801	19/8135	2.38	3.49e-03	2.73e-02	19
GO:0002507	GO:0002507	tolerance induction	10/1801	19/8135	2.38	3.49e-03	2.73e-02	19
GO:0036035	GO:0036035	osteoclast development	7/1801	11/8135	2.87	3.63e-03	2.83e-02	11
GO:0043383	GO:0043383	negative T cell selection	7/1801	11/8135	2.87	3.63e-03	2.83e-02	11
GO:0046629	GO:0046629	gamma-delta T cell activation	7/1801	11/8135	2.87	3.63e-03	2.83e-02	11
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	13/1801	28/8135	2.10	3.73e-03	2.88e-02	28
GO:0032731	GO:0032731	positive regulation of interleukin-1 beta production	13/1801	28/8135	2.10	3.73e-03	2.88e-02	28
GO:1902667	GO:1902667	regulation of axon guidance	13/1801	28/8135	2.10	3.73e-03	2.88e-02	28
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	26/1801	71/8135	1.65	3.77e-03	2.89e-02	71
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	12/1801	25/8135	2.17	3.77e-03	2.89e-02	25
GO:0030225	GO:0030225	macrophage differentiation	12/1801	25/8135	2.17	3.77e-03	2.89e-02	25
GO:0070555	GO:0070555	response to interleukin-1	31/1801	89/8135	1.57	4.02e-03	3.07e-02	89
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	24/1801	65/8135	1.67	4.67e-03	3.54e-02	65
GO:0002043	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	8/1801	14/8135	2.58	4.67e-03	3.54e-02	14
GO:0006957	GO:0006957	complement activation, alternative pathway	8/1801	14/8135	2.58	4.67e-03	3.54e-02	14
GO:1904706	GO:1904706	negative regulation of vascular smooth muscle cell proliferation	8/1801	14/8135	2.58	4.67e-03	3.54e-02	14
GO:0048662	GO:0048662	negative regulation of smooth muscle cell proliferation	15/1801	35/8135	1.94	4.86e-03	3.67e-02	35
GO:0030890	GO:0030890	positive regulation of B cell proliferation	14/1801	32/8135	1.98	5.16e-03	3.87e-02	32
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	14/1801	32/8135	1.98	5.16e-03	3.87e-02	32
GO:0071675	GO:0071675	regulation of mononuclear cell migration	14/1801	32/8135	1.98	5.16e-03	3.87e-02	32
GO:1903035	GO:1903035	negative regulation of response to wounding	23/1801	62/8135	1.68	5.19e-03	3.89e-02	62
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	9/1801	17/8135	2.39	5.30e-03	3.95e-02	17
GO:0046627	GO:0046627	negative regulation of insulin receptor signaling pathway	9/1801	17/8135	2.39	5.30e-03	3.95e-02	17
GO:1900077	GO:1900077	negative regulation of cellular response to insulin stimulus	9/1801	17/8135	2.39	5.30e-03	3.95e-02	17
GO:0006911	GO:0006911	phagocytosis, engulfment	13/1801	29/8135	2.02	5.42e-03	3.99e-02	29
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	13/1801	29/8135	2.02	5.42e-03	3.99e-02	29
GO:0002200	GO:0002200	somatic diversification of immune receptors	12/1801	26/8135	2.08	5.61e-03	4.09e-02	26
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	12/1801	26/8135	2.08	5.61e-03	4.09e-02	26
GO:0007202	GO:0007202	activation of phospholipase C activity	12/1801	26/8135	2.08	5.61e-03	4.09e-02	26
GO:0048260	GO:0048260	positive regulation of receptor-mediated endocytosis	12/1801	26/8135	2.08	5.61e-03	4.09e-02	26
GO:0010950	GO:0010950	positive regulation of endopeptidase activity	28/1801	80/8135	1.58	5.63e-03	4.10e-02	80
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	11/1801	23/8135	2.16	5.69e-03	4.12e-02	23
GO:0030851	GO:0030851	granulocyte differentiation	11/1801	23/8135	2.16	5.69e-03	4.12e-02	23
GO:0071320	GO:0071320	cellular response to cAMP	15/1801	36/8135	1.88	6.66e-03	4.75e-02	36
GO:0002374	GO:0002374	cytokine secretion involved in immune response	7/1801	12/8135	2.63	7.06e-03	4.98e-02	12
GO:0046133	GO:0046133	pyrimidine ribonucleoside catabolic process	7/1801	12/8135	2.63	7.06e-03	4.98e-02	12
GO:0071871	GO:0071871	response to epinephrine	7/1801	12/8135	2.63	7.06e-03	4.98e-02	12
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	20/1801	53/8135	1.70	7.12e-03	5.00e-02	53
GO:0061045	GO:0061045	negative regulation of wound healing	20/1801	53/8135	1.70	7.12e-03	5.00e-02	53

Factor 18 : 1 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0060602	GO:0060602	branch elongation of an epithelium	17/3586	18/8135	2.14	9.23e-06	0.0426	18

Factor 19 : 188 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001525	GO:0001525	angiogenesis	114/1611	306/8135	1.88	3.77e-13	1.19e-09	306
GO:0001944	GO:0001944	vasculature development	143/1611	417/8135	1.73	7.01e-13	1.19e-09	417
GO:0072358	GO:0072358	cardiovascular system development	144/1611	422/8135	1.72	8.95e-13	1.19e-09	422
GO:0001568	GO:0001568	blood vessel development	138/1611	401/8135	1.74	1.35e-12	1.24e-09	401
GO:0048514	GO:0048514	blood vessel morphogenesis	127/1611	360/8135	1.78	1.57e-12	1.24e-09	360
GO:0030334	GO:0030334	regulation of cell migration	153/1611	490/8135	1.58	3.82e-10	2.53e-07	490
GO:0098657	GO:0098657	import into cell	141/1611	445/8135	1.60	6.56e-10	3.72e-07	445
GO:0006897	GO:0006897	endocytosis	117/1611	357/8135	1.65	2.29e-09	1.14e-06	357
GO:0035239	GO:0035239	tube morphogenesis	151/1611	499/8135	1.53	5.76e-09	2.45e-06	499
GO:0043062	GO:0043062	extracellular structure organization	101/1611	300/8135	1.70	6.16e-09	2.45e-06	300
GO:0030198	GO:0030198	extracellular matrix organization	91/1611	264/8135	1.74	9.72e-09	3.51e-06	264
GO:0030335	GO:0030335	positive regulation of cell migration	96/1611	287/8135	1.69	2.14e-08	7.07e-06	287
GO:0002263	GO:0002263	cell activation involved in immune response	112/1611	356/8135	1.59	6.39e-08	1.95e-05	356
GO:0001935	GO:0001935	endothelial cell proliferation	37/1611	80/8135	2.34	7.21e-08	2.05e-05	80
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	34/1611	71/8135	2.42	8.44e-08	2.09e-05	71
GO:0002366	GO:0002366	leukocyte activation involved in immune response	111/1611	354/8135	1.58	8.92e-08	2.09e-05	354
GO:0003158	GO:0003158	endothelium development	30/1611	59/8135	2.57	8.93e-08	2.09e-05	59
GO:0040017	GO:0040017	positive regulation of locomotion	102/1611	319/8135	1.61	1.04e-07	2.29e-05	319
GO:1901342	GO:1901342	regulation of vasculature development	71/1611	200/8135	1.79	1.13e-07	2.36e-05	200
GO:2000147	GO:2000147	positive regulation of cell motility	97/1611	302/8135	1.62	1.69e-07	3.35e-05	302
GO:0051272	GO:0051272	positive regulation of cellular component movement	99/1611	311/8135	1.61	2.04e-07	3.86e-05	311
GO:0006898	GO:0006898	receptor-mediated endocytosis	64/1611	177/8135	1.83	2.23e-07	3.91e-05	177
GO:0045446	GO:0045446	endothelial cell differentiation	27/1611	52/8135	2.62	2.26e-07	3.91e-05	52
GO:0045765	GO:0045765	regulation of angiogenesis	64/1611	178/8135	1.82	2.82e-07	4.67e-05	178
GO:0001667	GO:0001667	ameboidal-type cell migration	71/1611	208/8135	1.72	6.39e-07	1.01e-04	208
GO:0050900	GO:0050900	leukocyte migration	96/1611	306/8135	1.58	6.61e-07	1.01e-04	306
GO:0003013	GO:0003013	circulatory system process	104/1611	342/8135	1.54	1.19e-06	1.75e-04	342
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	26/1611	53/8135	2.48	1.57e-06	2.23e-04	53
GO:0043542	GO:0043542	endothelial cell migration	40/1611	99/8135	2.04	1.77e-06	2.38e-04	99
GO:0090130	GO:0090130	tissue migration	54/1611	149/8135	1.83	1.80e-06	2.38e-04	149
GO:0003018	GO:0003018	vascular process in circulatory system	45/1611	117/8135	1.94	2.05e-06	2.55e-04	117
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	83/1611	261/8135	1.61	2.09e-06	2.55e-04	261
GO:0003170	GO:0003170	heart valve development	20/1611	36/8135	2.81	2.12e-06	2.55e-04	36
GO:0008015	GO:0008015	blood circulation	102/1611	338/8135	1.52	2.22e-06	2.59e-04	338
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	83/1611	262/8135	1.60	2.48e-06	2.81e-04	262
GO:0043299	GO:0043299	leukocyte degranulation	80/1611	254/8135	1.59	4.82e-06	5.29e-04	254
GO:0031623	GO:0031623	receptor internalization	28/1611	62/8135	2.28	4.98e-06	5.29e-04	62
GO:0002274	GO:0002274	myeloid leukocyte activation	98/1611	328/8135	1.51	5.66e-06	5.63e-04	328
GO:0090132	GO:0090132	epithelium migration	51/1611	143/8135	1.80	5.90e-06	5.72e-04	143
GO:0048844	GO:0048844	artery morphogenesis	20/1611	38/8135	2.66	6.47e-06	6.00e-04	38
GO:0090066	GO:0090066	regulation of anatomical structure size	87/1611	284/8135	1.55	6.49e-06	6.00e-04	284
GO:0072001	GO:0072001	renal system development	64/1611	194/8135	1.67	8.22e-06	7.43e-04	194
GO:0007507	GO:0007507	heart development	94/1611	315/8135	1.51	9.30e-06	8.22e-04	315
GO:0003179	GO:0003179	heart valve morphogenesis	18/1611	33/8135	2.75	9.77e-06	8.44e-04	33
GO:0010631	GO:0010631	epithelial cell migration	50/1611	142/8135	1.78	1.09e-05	9.24e-04	142
GO:0008360	GO:0008360	regulation of cell shape	32/1611	78/8135	2.07	1.29e-05	1.07e-03	78
GO:0043114	GO:0043114	regulation of vascular permeability	13/1611	20/8135	3.28	1.32e-05	1.07e-03	20
GO:0036230	GO:0036230	granulocyte activation	73/1611	233/8135	1.58	1.53e-05	1.22e-03	233
GO:0045123	GO:0045123	cellular extravasation	21/1611	43/8135	2.47	1.73e-05	1.35e-03	43
GO:0002283	GO:0002283	neutrophil activation involved in immune response	70/1611	222/8135	1.59	1.80e-05	1.35e-03	222
GO:0042119	GO:0042119	neutrophil activation	72/1611	230/8135	1.58	1.80e-05	1.35e-03	230
GO:0043312	GO:0043312	neutrophil degranulation	69/1611	219/8135	1.59	2.12e-05	1.54e-03	219
GO:0002446	GO:0002446	neutrophil mediated immunity	71/1611	227/8135	1.58	2.13e-05	1.54e-03	227
GO:1904018	GO:1904018	positive regulation of vasculature development	43/1611	119/8135	1.82	2.16e-05	1.54e-03	119
GO:0060326	GO:0060326	cell chemotaxis	69/1611	221/8135	1.58	2.95e-05	2.02e-03	221
GO:0045926	GO:0045926	negative regulation of growth	50/1611	147/8135	1.72	3.18e-05	2.08e-03	147
GO:0060485	GO:0060485	mesenchyme development	56/1611	171/8135	1.65	3.77e-05	2.37e-03	171
GO:0033627	GO:0033627	cell adhesion mediated by integrin	22/1611	48/8135	2.31	3.85e-05	2.37e-03	48
GO:0048762	GO:0048762	mesenchymal cell differentiation	45/1611	129/8135	1.76	3.87e-05	2.37e-03	129
GO:0001655	GO:0001655	urogenital system development	68/1611	219/8135	1.57	4.09e-05	2.43e-03	219
GO:0010594	GO:0010594	regulation of endothelial cell migration	30/1611	75/8135	2.02	4.27e-05	2.50e-03	75
GO:0050919	GO:0050919	negative chemotaxis	16/1611	30/8135	2.69	4.45e-05	2.55e-03	30
GO:0002040	GO:0002040	sprouting angiogenesis	27/1611	65/8135	2.10	4.67e-05	2.61e-03	65
GO:0043534	GO:0043534	blood vessel endothelial cell migration	23/1611	52/8135	2.23	5.19e-05	2.85e-03	52
GO:0003205	GO:0003205	cardiac chamber development	39/1611	108/8135	1.82	5.24e-05	2.85e-03	108
GO:0060840	GO:0060840	artery development	22/1611	49/8135	2.27	5.70e-05	3.06e-03	49
GO:0097529	GO:0097529	myeloid leukocyte migration	51/1611	154/8135	1.67	5.95e-05	3.10e-03	154
GO:0034329	GO:0034329	cell junction assembly	41/1611	116/8135	1.78	6.00e-05	3.10e-03	116
GO:0035150	GO:0035150	regulation of tube size	38/1611	105/8135	1.83	6.16e-05	3.14e-03	105
GO:0050673	GO:0050673	epithelial cell proliferation	70/1611	230/8135	1.54	6.47e-05	3.25e-03	230
GO:0001822	GO:0001822	kidney development	58/1611	182/8135	1.61	6.62e-05	3.27e-03	182
GO:0001570	GO:0001570	vasculogenesis	20/1611	43/8135	2.35	6.66e-05	3.27e-03	43
GO:0003007	GO:0003007	heart morphogenesis	53/1611	163/8135	1.64	7.47e-05	3.57e-03	163
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	16/1611	31/8135	2.61	7.51e-05	3.57e-03	31
GO:0003279	GO:0003279	cardiac septum development	27/1611	67/8135	2.03	8.76e-05	4.05e-03	67
GO:0045766	GO:0045766	positive regulation of angiogenesis	38/1611	107/8135	1.79	9.82e-05	4.49e-03	107
GO:1905314	GO:1905314	semi-lunar valve development	13/1611	23/8135	2.85	1.07e-04	4.79e-03	23
GO:0050678	GO:0050678	regulation of epithelial cell proliferation	61/1611	197/8135	1.56	1.10e-04	4.84e-03	197
GO:0050880	GO:0050880	regulation of blood vessel size	37/1611	104/8135	1.80	1.16e-04	4.95e-03	104
GO:0034330	GO:0034330	cell junction organization	48/1611	146/8135	1.66	1.19e-04	4.98e-03	146
GO:0001885	GO:0001885	endothelial cell development	15/1611	29/8135	2.61	1.22e-04	5.01e-03	29
GO:0060412	GO:0060412	ventricular septum morphogenesis	15/1611	29/8135	2.61	1.22e-04	5.01e-03	29
GO:0043112	GO:0043112	receptor metabolic process	32/1611	86/8135	1.88	1.26e-04	5.09e-03	86
GO:0031589	GO:0031589	cell-substrate adhesion	63/1611	206/8135	1.54	1.27e-04	5.09e-03	206
GO:0021954	GO:0021954	central nervous system neuron development	21/1611	48/8135	2.21	1.32e-04	5.26e-03	48
GO:0014031	GO:0014031	mesenchymal cell development	23/1611	55/8135	2.11	1.49e-04	5.79e-03	55
GO:0002698	GO:0002698	negative regulation of immune effector process	27/1611	69/8135	1.98	1.58e-04	6.10e-03	69
GO:0016525	GO:0016525	negative regulation of angiogenesis	25/1611	63/8135	2.00	2.12e-04	7.93e-03	63
GO:0050679	GO:0050679	positive regulation of epithelial cell proliferation	41/1611	122/8135	1.70	2.14e-04	7.96e-03	122
GO:0001945	GO:0001945	lymph vessel development	10/1611	16/8135	3.16	2.24e-04	8.15e-03	16
GO:0050920	GO:0050920	regulation of chemotaxis	47/1611	146/8135	1.63	2.43e-04	8.79e-03	146
GO:0030168	GO:0030168	platelet activation	35/1611	100/8135	1.77	2.53e-04	8.81e-03	100
GO:0035296	GO:0035296	regulation of tube diameter	35/1611	100/8135	1.77	2.53e-04	8.81e-03	100
GO:0097746	GO:0097746	regulation of blood vessel diameter	35/1611	100/8135	1.77	2.53e-04	8.81e-03	100
GO:0050777	GO:0050777	negative regulation of immune response	32/1611	89/8135	1.82	2.63e-04	9.08e-03	89
GO:0032102	GO:0032102	negative regulation of response to external stimulus	62/1611	207/8135	1.51	2.72e-04	9.23e-03	207
GO:0060348	GO:0060348	bone development	44/1611	135/8135	1.65	2.79e-04	9.29e-03	135
GO:0072132	GO:0072132	mesenchyme morphogenesis	17/1611	37/8135	2.32	2.81e-04	9.29e-03	37
GO:0040013	GO:0040013	negative regulation of locomotion	56/1611	183/8135	1.55	2.90e-04	9.45e-03	183
GO:0003281	GO:0003281	ventricular septum development	20/1611	47/8135	2.15	3.00e-04	9.69e-03	47
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	12/1611	22/8135	2.75	3.10e-04	9.95e-03	22
GO:0003206	GO:0003206	cardiac chamber morphogenesis	32/1611	90/8135	1.80	3.31e-04	1.05e-02	90
GO:0086065	GO:0086065	cell communication involved in cardiac conduction	19/1611	44/8135	2.18	3.37e-04	1.05e-02	44
GO:0010632	GO:0010632	regulation of epithelial cell migration	37/1611	109/8135	1.71	3.42e-04	1.06e-02	109
GO:0003177	GO:0003177	pulmonary valve development	9/1611	14/8135	3.25	3.48e-04	1.07e-02	14
GO:0031348	GO:0031348	negative regulation of defense response	39/1611	117/8135	1.68	3.65e-04	1.10e-02	117
GO:0060411	GO:0060411	cardiac septum morphogenesis	21/1611	51/8135	2.08	3.68e-04	1.10e-02	51
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	25/1611	65/8135	1.94	3.74e-04	1.11e-02	65
GO:0048864	GO:0048864	stem cell development	22/1611	55/8135	2.02	4.38e-04	1.26e-02	55
GO:0003231	GO:0003231	cardiac ventricle development	30/1611	84/8135	1.80	4.61e-04	1.30e-02	84
GO:0006909	GO:0006909	phagocytosis	41/1611	126/8135	1.64	4.62e-04	1.30e-02	126
GO:1901343	GO:1901343	negative regulation of vasculature development	27/1611	73/8135	1.87	4.63e-04	1.30e-02	73
GO:0032387	GO:0032387	negative regulation of intracellular transport	15/1611	32/8135	2.37	4.89e-04	1.35e-02	32
GO:0033628	GO:0033628	regulation of cell adhesion mediated by integrin	15/1611	32/8135	2.37	4.89e-04	1.35e-02	32
GO:0045216	GO:0045216	cell-cell junction organization	31/1611	88/8135	1.78	4.91e-04	1.35e-02	88
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	21/1611	52/8135	2.04	5.04e-04	1.36e-02	52
GO:0014032	GO:0014032	neural crest cell development	21/1611	52/8135	2.04	5.04e-04	1.36e-02	52
GO:0035904	GO:0035904	aorta development	14/1611	29/8135	2.44	5.17e-04	1.38e-02	29
GO:0048846	GO:0048846	axon extension involved in axon guidance	13/1611	26/8135	2.52	5.34e-04	1.40e-02	26
GO:1902284	GO:1902284	neuron projection extension involved in neuron projection guidance	13/1611	26/8135	2.52	5.34e-04	1.40e-02	26
GO:0030308	GO:0030308	negative regulation of cell growth	33/1611	96/8135	1.74	5.44e-04	1.41e-02	96
GO:0048863	GO:0048863	stem cell differentiation	41/1611	127/8135	1.63	5.54e-04	1.42e-02	127
GO:0036293	GO:0036293	response to decreased oxygen levels	52/1611	171/8135	1.54	5.55e-04	1.42e-02	171
GO:0003151	GO:0003151	outflow tract morphogenesis	22/1611	56/8135	1.98	5.88e-04	1.49e-02	56
GO:0014909	GO:0014909	smooth muscle cell migration	17/1611	39/8135	2.20	6.01e-04	1.50e-02	39
GO:0001666	GO:0001666	response to hypoxia	51/1611	168/8135	1.53	6.53e-04	1.61e-02	168
GO:0007160	GO:0007160	cell-matrix adhesion	41/1611	128/8135	1.62	6.62e-04	1.62e-02	128
GO:0042310	GO:0042310	vasoconstriction	23/1611	60/8135	1.94	6.70e-04	1.62e-02	60
GO:0051216	GO:0051216	cartilage development	46/1611	148/8135	1.57	6.73e-04	1.62e-02	148
GO:1904019	GO:1904019	epithelial cell apoptotic process	21/1611	53/8135	2.00	6.82e-04	1.63e-02	53
GO:0001991	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	9/1611	15/8135	3.03	7.18e-04	1.70e-02	15
GO:1900181	GO:1900181	negative regulation of protein localization to nucleus	9/1611	15/8135	3.03	7.18e-04	1.70e-02	15
GO:0051271	GO:0051271	negative regulation of cellular component movement	54/1611	181/8135	1.51	7.29e-04	1.71e-02	181
GO:0010977	GO:0010977	negative regulation of neuron projection development	31/1611	90/8135	1.74	7.61e-04	1.78e-02	90
GO:0014033	GO:0014033	neural crest cell differentiation	22/1611	57/8135	1.95	7.81e-04	1.81e-02	57
GO:0036303	GO:0036303	lymph vessel morphogenesis	7/1611	10/8135	3.53	8.05e-04	1.81e-02	10
GO:0048484	GO:0048484	enteric nervous system development	7/1611	10/8135	3.53	8.05e-04	1.81e-02	10
GO:0086016	GO:0086016	AV node cell action potential	7/1611	10/8135	3.53	8.05e-04	1.81e-02	10
GO:0086027	GO:0086027	AV node cell to bundle of His cell signaling	7/1611	10/8135	3.53	8.05e-04	1.81e-02	10
GO:0086067	GO:0086067	AV node cell to bundle of His cell communication	7/1611	10/8135	3.53	8.05e-04	1.81e-02	10
GO:0035909	GO:0035909	aorta morphogenesis	10/1611	18/8135	2.81	8.27e-04	1.84e-02	18
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	13/1611	27/8135	2.43	8.45e-04	1.85e-02	27
GO:0086019	GO:0086019	cell-cell signaling involved in cardiac conduction	13/1611	27/8135	2.43	8.45e-04	1.85e-02	27
GO:0003203	GO:0003203	endocardial cushion morphogenesis	12/1611	24/8135	2.52	8.75e-04	1.90e-02	24
GO:0071526	GO:0071526	semaphorin-plexin signaling pathway	12/1611	24/8135	2.52	8.75e-04	1.90e-02	24
GO:0019935	GO:0019935	cyclic-nucleotide-mediated signaling	48/1611	158/8135	1.53	9.12e-04	1.97e-02	158
GO:0007043	GO:0007043	cell-cell junction assembly	24/1611	65/8135	1.86	9.68e-04	2.06e-02	65
GO:0007229	GO:0007229	integrin-mediated signaling pathway	24/1611	65/8135	1.86	9.68e-04	2.06e-02	65
GO:0003184	GO:0003184	pulmonary valve morphogenesis	8/1611	13/8135	3.11	1.15e-03	2.38e-02	13
GO:0010919	GO:0010919	regulation of inositol phosphate biosynthetic process	8/1611	13/8135	3.11	1.15e-03	2.38e-02	13
GO:0045648	GO:0045648	positive regulation of erythrocyte differentiation	8/1611	13/8135	3.11	1.15e-03	2.38e-02	13
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	14/1611	31/8135	2.28	1.19e-03	2.45e-02	31
GO:0030336	GO:0030336	negative regulation of cell migration	46/1611	152/8135	1.53	1.26e-03	2.58e-02	152
GO:0097530	GO:0097530	granulocyte migration	36/1611	112/8135	1.62	1.28e-03	2.61e-02	112
GO:0002685	GO:0002685	regulation of leukocyte migration	41/1611	132/8135	1.57	1.31e-03	2.65e-02	132
GO:0003171	GO:0003171	atrioventricular valve development	9/1611	16/8135	2.84	1.35e-03	2.72e-02	16
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	16/1611	38/8135	2.13	1.36e-03	2.72e-02	38
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	12/1611	25/8135	2.42	1.38e-03	2.73e-02	25
GO:0072677	GO:0072677	eosinophil migration	12/1611	25/8135	2.42	1.38e-03	2.73e-02	25
GO:1902668	GO:1902668	negative regulation of axon guidance	10/1611	19/8135	2.66	1.44e-03	2.83e-02	19
GO:0097756	GO:0097756	negative regulation of blood vessel diameter	23/1611	63/8135	1.84	1.46e-03	2.86e-02	63
GO:0051145	GO:0051145	smooth muscle cell differentiation	15/1611	35/8135	2.16	1.54e-03	2.99e-02	35
GO:0050918	GO:0050918	positive chemotaxis	19/1611	49/8135	1.96	1.64e-03	3.14e-02	49
GO:0097755	GO:0097755	positive regulation of blood vessel diameter	17/1611	42/8135	2.04	1.64e-03	3.14e-02	42
GO:0030856	GO:0030856	regulation of epithelial cell differentiation	30/1611	90/8135	1.68	1.67e-03	3.17e-02	90
GO:0002523	GO:0002523	leukocyte migration involved in inflammatory response	7/1611	11/8135	3.21	1.83e-03	3.39e-02	11
GO:0061162	GO:0061162	establishment of monopolar cell polarity	7/1611	11/8135	3.21	1.83e-03	3.39e-02	11
GO:1901888	GO:1901888	regulation of cell junction assembly	16/1611	39/8135	2.07	1.89e-03	3.47e-02	39
GO:0003073	GO:0003073	regulation of systemic arterial blood pressure	24/1611	68/8135	1.78	1.99e-03	3.62e-02	68
GO:0051495	GO:0051495	positive regulation of cytoskeleton organization	31/1611	95/8135	1.65	2.07e-03	3.75e-02	95
GO:0071621	GO:0071621	granulocyte chemotaxis	33/1611	103/8135	1.62	2.12e-03	3.82e-02	103
GO:0042157	GO:0042157	lipoprotein metabolic process	19/1611	50/8135	1.92	2.16e-03	3.86e-02	50
GO:0014910	GO:0014910	regulation of smooth muscle cell migration	15/1611	36/8135	2.10	2.17e-03	3.86e-02	36
GO:0003181	GO:0003181	atrioventricular valve morphogenesis	8/1611	14/8135	2.89	2.22e-03	3.91e-02	14
GO:0014912	GO:0014912	negative regulation of smooth muscle cell migration	8/1611	14/8135	2.89	2.22e-03	3.91e-02	14
GO:0045646	GO:0045646	regulation of erythrocyte differentiation	10/1611	20/8135	2.52	2.37e-03	4.10e-02	20
GO:0086014	GO:0086014	atrial cardiac muscle cell action potential	9/1611	17/8135	2.67	2.38e-03	4.10e-02	17
GO:0086026	GO:0086026	atrial cardiac muscle cell to AV node cell signaling	9/1611	17/8135	2.67	2.38e-03	4.10e-02	17
GO:0086066	GO:0086066	atrial cardiac muscle cell to AV node cell communication	9/1611	17/8135	2.67	2.38e-03	4.10e-02	17
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	33/1611	104/8135	1.60	2.53e-03	4.30e-02	104
GO:0030323	GO:0030323	respiratory tube development	35/1611	112/8135	1.58	2.54e-03	4.30e-02	112
GO:0003044	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	16/1611	40/8135	2.02	2.58e-03	4.34e-02	40
GO:0001942	GO:0001942	hair follicle development	21/1611	58/8135	1.83	2.60e-03	4.36e-02	58
GO:0003197	GO:0003197	endocardial cushion development	13/1611	30/8135	2.19	2.79e-03	4.56e-02	30
GO:0043300	GO:0043300	regulation of leukocyte degranulation	13/1611	30/8135	2.19	2.79e-03	4.56e-02	30
GO:0048659	GO:0048659	smooth muscle cell proliferation	29/1611	89/8135	1.65	2.91e-03	4.71e-02	89
GO:0034113	GO:0034113	heterotypic cell-cell adhesion	17/1611	44/8135	1.95	2.97e-03	4.79e-02	44
GO:0014074	GO:0014074	response to purine-containing compound	32/1611	101/8135	1.60	3.00e-03	4.82e-02	101

Factor 20 : 756 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0046649	GO:0046649	lymphocyte activation	217/1389	397/8135	3.20	4.94e-69	1.80e-65	397
GO:0002250	GO:0002250	adaptive immune response	163/1389	269/8135	3.55	4.22e-60	7.71e-57	269
GO:0042110	GO:0042110	T cell activation	166/1389	285/8135	3.41	1.01e-57	1.23e-54	285
GO:0045087	GO:0045087	innate immune response	227/1389	485/8135	2.74	5.34e-56	4.87e-53	485
GO:0050778	GO:0050778	positive regulation of immune response	206/1389	423/8135	2.85	3.49e-54	2.54e-51	423
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	213/1389	459/8135	2.72	1.33e-51	8.08e-49	459
GO:0002694	GO:0002694	regulation of leukocyte activation	166/1389	316/8135	3.08	3.61e-49	1.88e-46	316
GO:0050865	GO:0050865	regulation of cell activation	170/1389	344/8135	2.89	1.41e-45	6.44e-43	344
GO:0051249	GO:0051249	regulation of lymphocyte activation	143/1389	260/8135	3.22	1.86e-45	7.56e-43	260
GO:0050863	GO:0050863	regulation of T cell activation	120/1389	203/8135	3.46	1.48e-42	5.39e-40	203
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	125/1389	218/8135	3.36	2.41e-42	8.01e-40	218
GO:0030098	GO:0030098	lymphocyte differentiation	120/1389	214/8135	3.28	2.66e-39	8.10e-37	214
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	112/1389	196/8135	3.35	9.00e-38	2.53e-35	196
GO:0002696	GO:0002696	positive regulation of leukocyte activation	114/1389	202/8135	3.31	1.01e-37	2.65e-35	202
GO:0050867	GO:0050867	positive regulation of cell activation	116/1389	210/8135	3.24	3.91e-37	9.51e-35	210
GO:0002521	GO:0002521	leukocyte differentiation	150/1389	318/8135	2.76	4.36e-37	9.95e-35	318
GO:0002253	GO:0002253	activation of immune response	144/1389	302/8135	2.79	2.87e-36	6.17e-34	302
GO:0002443	GO:0002443	leukocyte mediated immunity	174/1389	410/8135	2.49	1.49e-35	3.03e-33	410
GO:0001816	GO:0001816	cytokine production	182/1389	444/8135	2.40	8.72e-35	1.68e-32	444
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	99/1389	170/8135	3.41	2.05e-34	3.74e-32	170
GO:0002757	GO:0002757	immune response-activating signal transduction	125/1389	249/8135	2.94	2.41e-34	4.19e-32	249
GO:0009615	GO:0009615	response to virus	96/1389	162/8135	3.47	2.88e-34	4.78e-32	162
GO:0002764	GO:0002764	immune response-regulating signaling pathway	131/1389	270/8135	2.84	5.41e-34	8.34e-32	270
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	91/1389	149/8135	3.58	5.48e-34	8.34e-32	149
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	97/1389	168/8135	3.38	2.64e-33	3.86e-31	168
GO:0030097	GO:0030097	hemopoiesis	183/1389	459/8135	2.34	4.40e-33	6.17e-31	459
GO:0002449	GO:0002449	lymphocyte mediated immunity	94/1389	161/8135	3.42	7.75e-33	1.05e-30	161
GO:0050870	GO:0050870	positive regulation of T cell activation	86/1389	139/8135	3.62	8.98e-33	1.17e-30	139
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	96/1389	167/8135	3.37	9.42e-33	1.19e-30	167
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	103/1389	189/8135	3.19	2.38e-32	2.89e-30	189
GO:0001817	GO:0001817	regulation of cytokine production	167/1389	406/8135	2.41	4.27e-32	5.03e-30	406
GO:0002697	GO:0002697	regulation of immune effector process	122/1389	251/8135	2.85	8.94e-32	1.02e-29	251
GO:0048534	GO:0048534	hematopoietic or lymphoid organ development	187/1389	487/8135	2.25	2.83e-31	3.13e-29	487
GO:0051607	GO:0051607	defense response to virus	76/1389	118/8135	3.77	8.84e-31	9.43e-29	118
GO:0046651	GO:0046651	lymphocyte proliferation	97/1389	177/8135	3.21	9.04e-31	9.43e-29	177
GO:0030217	GO:0030217	T cell differentiation	88/1389	151/8135	3.41	1.04e-30	1.06e-28	151
GO:0070661	GO:0070661	leukocyte proliferation	102/1389	193/8135	3.10	1.53e-30	1.51e-28	193
GO:0031347	GO:0031347	regulation of defense response	169/1389	425/8135	2.33	2.35e-30	2.26e-28	425
GO:0098542	GO:0098542	defense response to other organism	125/1389	268/8135	2.73	2.50e-30	2.34e-28	268
GO:0032943	GO:0032943	mononuclear cell proliferation	97/1389	179/8135	3.17	3.06e-30	2.79e-28	179
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	71/1389	108/8135	3.85	1.16e-29	1.03e-27	108
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	95/1389	177/8135	3.14	3.40e-29	2.95e-27	177
GO:0022407	GO:0022407	regulation of cell-cell adhesion	119/1389	260/8135	2.68	5.89e-28	5.00e-26	260
GO:0001819	GO:0001819	positive regulation of cytokine production	122/1389	271/8135	2.64	8.09e-28	6.72e-26	271
GO:0070663	GO:0070663	regulation of leukocyte proliferation	86/1389	158/8135	3.19	4.31e-27	3.50e-25	158
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	83/1389	150/8135	3.24	7.60e-27	6.03e-25	150
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	83/1389	151/8135	3.22	1.41e-26	1.10e-24	151
GO:0002263	GO:0002263	cell activation involved in immune response	143/1389	356/8135	2.35	3.22e-26	2.45e-24	356
GO:0002366	GO:0002366	leukocyte activation involved in immune response	142/1389	354/8135	2.35	5.77e-26	4.30e-24	354
GO:0042113	GO:0042113	B cell activation	76/1389	134/8135	3.32	1.34e-25	9.80e-24	134
GO:0034341	GO:0034341	response to interferon-gamma	72/1389	126/8135	3.35	1.41e-24	1.01e-22	126
GO:0002819	GO:0002819	regulation of adaptive immune response	64/1389	105/8135	3.57	3.98e-24	2.79e-22	105
GO:0042098	GO:0042098	T cell proliferation	69/1389	120/8135	3.37	8.09e-24	5.57e-22	120
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	64/1389	106/8135	3.54	8.41e-24	5.69e-22	106
GO:0046631	GO:0046631	alpha-beta T cell activation	59/1389	93/8135	3.72	1.25e-23	8.29e-22	93
GO:0030155	GO:0030155	regulation of cell adhesion	154/1389	419/8135	2.15	2.13e-23	1.39e-21	419
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	62/1389	102/8135	3.56	2.57e-23	1.65e-21	102
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	62/1389	103/8135	3.53	5.41e-23	3.40e-21	103
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	59/1389	95/8135	3.64	6.21e-23	3.84e-21	95
GO:0045785	GO:0045785	positive regulation of cell adhesion	111/1389	262/8135	2.48	1.07e-22	6.49e-21	262
GO:0002683	GO:0002683	negative regulation of immune system process	114/1389	273/8135	2.45	1.16e-22	6.86e-21	273
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	72/1389	133/8135	3.17	1.16e-22	6.86e-21	133
GO:0042102	GO:0042102	positive regulation of T cell proliferation	51/1389	76/8135	3.93	3.05e-22	1.77e-20	76
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	61/1389	104/8135	3.44	8.22e-22	4.69e-20	104
GO:0050852	GO:0050852	T cell receptor signaling pathway	52/1389	80/8135	3.81	1.10e-21	6.19e-20	80
GO:0034340	GO:0034340	response to type I interferon	38/1389	47/8135	4.74	1.22e-21	6.54e-20	47
GO:0060337	GO:0060337	type I interferon signaling pathway	38/1389	47/8135	4.74	1.22e-21	6.54e-20	47
GO:0071357	GO:0071357	cellular response to type I interferon	38/1389	47/8135	4.74	1.22e-21	6.54e-20	47
GO:0042129	GO:0042129	regulation of T cell proliferation	62/1389	108/8135	3.36	1.82e-21	9.60e-20	108
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	46/1389	66/8135	4.08	3.05e-21	1.59e-19	66
GO:0071346	GO:0071346	cellular response to interferon-gamma	63/1389	112/8135	3.29	3.77e-21	1.94e-19	112
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	58/1389	98/8135	3.47	4.55e-21	2.31e-19	98
GO:0002821	GO:0002821	positive regulation of adaptive immune response	47/1389	69/8135	3.99	5.15e-21	2.57e-19	69
GO:0002699	GO:0002699	positive regulation of immune effector process	72/1389	140/8135	3.01	6.26e-21	3.09e-19	140
GO:0050900	GO:0050900	leukocyte migration	118/1389	306/8135	2.26	5.30e-20	2.55e-18	306
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	46/1389	69/8135	3.90	5.30e-20	2.55e-18	69
GO:0032609	GO:0032609	interferon-gamma production	53/1389	88/8135	3.53	7.61e-20	3.61e-18	88
GO:0031349	GO:0031349	positive regulation of defense response	104/1389	257/8135	2.37	1.58e-19	7.38e-18	257
GO:0045088	GO:0045088	regulation of innate immune response	87/1389	198/8135	2.57	3.15e-19	1.45e-17	198
GO:0002274	GO:0002274	myeloid leukocyte activation	122/1389	328/8135	2.18	3.87e-19	1.77e-17	328
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	51/1389	85/8135	3.51	4.85e-19	2.17e-17	85
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	59/1389	108/8135	3.20	4.87e-19	2.17e-17	108
GO:0002286	GO:0002286	T cell activation involved in immune response	43/1389	64/8135	3.93	5.62e-19	2.47e-17	64
GO:0016032	GO:0016032	viral process	90/1389	211/8135	2.50	8.21e-19	3.57e-17	211
GO:0002695	GO:0002695	negative regulation of leukocyte activation	58/1389	108/8135	3.15	2.91e-18	1.25e-16	108
GO:0032649	GO:0032649	regulation of interferon-gamma production	48/1389	80/8135	3.51	5.39e-18	2.29e-16	80
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	46/1389	75/8135	3.59	7.75e-18	3.25e-16	75
GO:0045580	GO:0045580	regulation of T cell differentiation	51/1389	89/8135	3.36	7.89e-18	3.27e-16	89
GO:0044419	GO:0044419	interspecies interaction between organisms	105/1389	273/8135	2.25	8.48e-18	3.45e-16	273
GO:1902105	GO:1902105	regulation of leukocyte differentiation	78/1389	175/8135	2.61	8.50e-18	3.45e-16	175
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	37/1389	53/8135	4.09	2.30e-17	9.22e-16	53
GO:0044403	GO:0044403	symbiont process	96/1389	245/8135	2.29	5.51e-17	2.19e-15	245
GO:0046632	GO:0046632	alpha-beta T cell differentiation	43/1389	70/8135	3.60	8.58e-17	3.37e-15	70
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	38/1389	57/8135	3.90	9.67e-17	3.75e-15	57
GO:0031341	GO:0031341	regulation of cell killing	42/1389	68/8135	3.62	1.48e-16	5.69e-15	68
GO:0009617	GO:0009617	response to bacterium	133/1389	398/8135	1.96	3.02e-16	1.15e-14	398
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	49/1389	89/8135	3.22	3.29e-16	1.23e-14	89
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	39/1389	61/8135	3.74	3.29e-16	1.23e-14	61
GO:0050864	GO:0050864	regulation of B cell activation	43/1389	72/8135	3.50	3.79e-16	1.40e-14	72
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	40/1389	64/8135	3.66	4.36e-16	1.59e-14	64
GO:0006968	GO:0006968	cellular defense response	34/1389	49/8135	4.06	6.25e-16	2.26e-14	49
GO:0002456	GO:0002456	T cell mediated immunity	42/1389	70/8135	3.51	6.63e-16	2.37e-14	70
GO:0050866	GO:0050866	negative regulation of cell activation	59/1389	123/8135	2.81	1.50e-15	5.31e-14	123
GO:1903706	GO:1903706	regulation of hemopoiesis	92/1389	241/8135	2.24	1.76e-15	6.16e-14	241
GO:0045089	GO:0045089	positive regulation of innate immune response	72/1389	169/8135	2.50	3.03e-15	1.05e-13	169
GO:0050663	GO:0050663	cytokine secretion	65/1389	145/8135	2.63	3.52e-15	1.20e-13	145
GO:0050727	GO:0050727	regulation of inflammatory response	94/1389	251/8135	2.19	3.52e-15	1.20e-13	251
GO:0001906	GO:0001906	cell killing	53/1389	106/8135	2.93	4.67e-15	1.58e-13	106
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	37/1389	59/8135	3.67	4.79e-15	1.60e-13	59
GO:0031295	GO:0031295	T cell costimulation	28/1389	37/8135	4.43	6.47e-15	2.15e-13	37
GO:0001818	GO:0001818	negative regulation of cytokine production	70/1389	165/8135	2.48	9.65e-15	3.17e-13	165
GO:0002440	GO:0002440	production of molecular mediator of immune response	55/1389	115/8135	2.80	1.63e-14	5.32e-13	115
GO:0031294	GO:0031294	lymphocyte costimulation	28/1389	38/8135	4.32	2.06e-14	6.66e-13	38
GO:0045058	GO:0045058	T cell selection	27/1389	36/8135	4.39	2.92e-14	9.34e-13	36
GO:0050868	GO:0050868	negative regulation of T cell activation	39/1389	67/8135	3.41	3.01e-14	9.55e-13	67
GO:0031343	GO:0031343	positive regulation of cell killing	32/1389	49/8135	3.82	6.47e-14	2.03e-12	49
GO:0019882	GO:0019882	antigen processing and presentation	44/1389	83/8135	3.10	6.78e-14	2.12e-12	83
GO:0002292	GO:0002292	T cell differentiation involved in immune response	30/1389	44/8135	3.99	6.94e-14	2.15e-12	44
GO:0050707	GO:0050707	regulation of cytokine secretion	58/1389	129/8135	2.63	9.44e-14	2.90e-12	129
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	41/1389	75/8135	3.20	1.23e-13	3.75e-12	75
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	32/1389	50/8135	3.75	1.50e-13	4.54e-12	50
GO:0043900	GO:0043900	regulation of multi-organism process	74/1389	188/8135	2.31	1.79e-13	5.35e-12	188
GO:0043901	GO:0043901	negative regulation of multi-organism process	46/1389	91/8135	2.96	1.83e-13	5.42e-12	91
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	29/1389	43/8135	3.95	2.82e-13	8.32e-12	43
GO:0002377	GO:0002377	immunoglobulin production	32/1389	51/8135	3.67	3.38e-13	9.88e-12	51
GO:0071887	GO:0071887	leukocyte apoptotic process	38/1389	68/8135	3.27	3.86e-13	1.12e-11	68
GO:0072676	GO:0072676	lymphocyte migration	42/1389	80/8135	3.07	3.92e-13	1.12e-11	80
GO:0050853	GO:0050853	B cell receptor signaling pathway	26/1389	36/8135	4.23	3.94e-13	1.12e-11	36
GO:1903901	GO:1903901	negative regulation of viral life cycle	27/1389	39/8135	4.05	7.14e-13	2.02e-11	39
GO:0002709	GO:0002709	regulation of T cell mediated immunity	30/1389	47/8135	3.74	9.74e-13	2.73e-11	47
GO:1903900	GO:1903900	regulation of viral life cycle	34/1389	58/8135	3.43	1.03e-12	2.88e-11	58
GO:0042100	GO:0042100	B cell proliferation	35/1389	61/8135	3.36	1.15e-12	3.18e-11	61
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	36/1389	64/8135	3.29	1.24e-12	3.39e-11	64
GO:0043368	GO:0043368	positive T cell selection	21/1389	26/8135	4.73	1.83e-12	4.98e-11	26
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	46/1389	96/8135	2.81	2.17e-12	5.86e-11	96
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	35/1389	62/8135	3.31	2.21e-12	5.94e-11	62
GO:0045071	GO:0045071	negative regulation of viral genome replication	24/1389	33/8135	4.26	2.53e-12	6.73e-11	33
GO:0002228	GO:0002228	natural killer cell mediated immunity	28/1389	43/8135	3.81	2.73e-12	7.23e-11	43
GO:0019058	GO:0019058	viral life cycle	52/1389	119/8135	2.56	7.09e-12	1.86e-10	119
GO:0048525	GO:0048525	negative regulation of viral process	29/1389	47/8135	3.61	8.12e-12	2.12e-10	47
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	20/1389	25/8135	4.69	8.76e-12	2.27e-10	25
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	23/1389	32/8135	4.21	1.09e-11	2.81e-10	32
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	46/1389	100/8135	2.69	1.32e-11	3.38e-10	100
GO:0019724	GO:0019724	B cell mediated immunity	37/1389	71/8135	3.05	1.33e-11	3.38e-10	71
GO:0034612	GO:0034612	response to tumor necrosis factor	60/1389	150/8135	2.34	1.65e-11	4.15e-10	150
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	26/1389	40/8135	3.81	1.78e-11	4.38e-10	40
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	26/1389	40/8135	3.81	1.78e-11	4.38e-10	40
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	26/1389	40/8135	3.81	1.78e-11	4.38e-10	40
GO:0032103	GO:0032103	positive regulation of response to external stimulus	75/1389	208/8135	2.11	2.07e-11	5.08e-10	208
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	88/1389	261/8135	1.97	2.48e-11	6.03e-10	261
GO:0060326	GO:0060326	cell chemotaxis	78/1389	221/8135	2.07	2.78e-11	6.72e-10	221
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	88/1389	262/8135	1.97	3.12e-11	7.50e-10	262
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	57/1389	141/8135	2.37	3.23e-11	7.70e-10	141
GO:1903708	GO:1903708	positive regulation of hemopoiesis	49/1389	113/8135	2.54	4.04e-11	9.57e-10	113
GO:0045069	GO:0045069	regulation of viral genome replication	26/1389	41/8135	3.71	4.07e-11	9.59e-10	41
GO:0016064	GO:0016064	immunoglobulin mediated immune response	36/1389	70/8135	3.01	4.17e-11	9.69e-10	70
GO:0050792	GO:0050792	regulation of viral process	36/1389	70/8135	3.01	4.17e-11	9.69e-10	70
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	41/1389	86/8135	2.79	4.23e-11	9.77e-10	86
GO:0002831	GO:0002831	regulation of response to biotic stimulus	35/1389	67/8135	3.06	4.38e-11	9.98e-10	67
GO:0030183	GO:0030183	B cell differentiation	35/1389	67/8135	3.06	4.38e-11	9.98e-10	67
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	22/1389	31/8135	4.16	4.67e-11	1.06e-09	31
GO:0001913	GO:0001913	T cell mediated cytotoxicity	24/1389	36/8135	3.90	4.84e-11	1.09e-09	36
GO:0002685	GO:0002685	regulation of leukocyte migration	54/1389	132/8135	2.40	6.24e-11	1.40e-09	132
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	25/1389	39/8135	3.75	6.88e-11	1.53e-09	39
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	48/1389	111/8135	2.53	7.20e-11	1.59e-09	111
GO:0036230	GO:0036230	granulocyte activation	80/1389	233/8135	2.01	7.45e-11	1.64e-09	233
GO:0043299	GO:0043299	leukocyte degranulation	85/1389	254/8135	1.96	8.51e-11	1.86e-09	254
GO:0042119	GO:0042119	neutrophil activation	79/1389	230/8135	2.01	9.62e-11	2.09e-09	230
GO:0050871	GO:0050871	positive regulation of B cell activation	27/1389	45/8135	3.51	1.09e-10	2.35e-09	45
GO:0019079	GO:0019079	viral genome replication	29/1389	51/8135	3.33	1.37e-10	2.94e-09	51
GO:0001776	GO:0001776	leukocyte homeostasis	32/1389	60/8135	3.12	1.47e-10	3.14e-09	60
GO:0045582	GO:0045582	positive regulation of T cell differentiation	31/1389	57/8135	3.19	1.48e-10	3.14e-09	57
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	25/1389	40/8135	3.66	1.54e-10	3.25e-09	40
GO:0050777	GO:0050777	negative regulation of immune response	41/1389	89/8135	2.70	1.63e-10	3.42e-09	89
GO:0072678	GO:0072678	T cell migration	26/1389	43/8135	3.54	1.90e-10	3.96e-09	43
GO:0048872	GO:0048872	homeostasis of number of cells	52/1389	128/8135	2.38	1.92e-10	3.98e-09	128
GO:0035456	GO:0035456	response to interferon-beta	14/1389	15/8135	5.47	2.14e-10	4.41e-09	15
GO:0030888	GO:0030888	regulation of B cell proliferation	27/1389	46/8135	3.44	2.21e-10	4.53e-09	46
GO:0030595	GO:0030595	leukocyte chemotaxis	63/1389	170/8135	2.17	2.35e-10	4.80e-09	170
GO:0001773	GO:0001773	myeloid dendritic cell activation	17/1389	21/8135	4.74	2.45e-10	4.97e-09	21
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	32/1389	61/8135	3.07	2.60e-10	5.24e-09	61
GO:0002237	GO:0002237	response to molecule of bacterial origin	76/1389	222/8135	2.01	2.64e-10	5.26e-09	222
GO:0002283	GO:0002283	neutrophil activation involved in immune response	76/1389	222/8135	2.01	2.64e-10	5.26e-09	222
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	16/1389	19/8135	4.93	2.80e-10	5.55e-09	19
GO:0050688	GO:0050688	regulation of defense response to virus	22/1389	33/8135	3.90	3.16e-10	6.24e-09	33
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	26/1389	44/8135	3.46	3.90e-10	7.65e-09	44
GO:0030101	GO:0030101	natural killer cell activation	28/1389	50/8135	3.28	4.66e-10	9.09e-09	50
GO:0032496	GO:0032496	response to lipopolysaccharide	73/1389	213/8135	2.01	5.66e-10	1.10e-08	213
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	24/1389	39/8135	3.60	5.74e-10	1.11e-08	39
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	37/1389	79/8135	2.74	7.15e-10	1.37e-08	79
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	22/1389	34/8135	3.79	7.52e-10	1.44e-08	34
GO:1990868	GO:1990868	response to chemokine	39/1389	86/8135	2.66	8.12e-10	1.54e-08	86
GO:1990869	GO:1990869	cellular response to chemokine	39/1389	86/8135	2.66	8.12e-10	1.54e-08	86
GO:0002446	GO:0002446	neutrophil mediated immunity	76/1389	227/8135	1.96	8.53e-10	1.60e-08	227
GO:0050729	GO:0050729	positive regulation of inflammatory response	43/1389	100/8135	2.52	8.78e-10	1.64e-08	100
GO:0043312	GO:0043312	neutrophil degranulation	74/1389	219/8135	1.98	8.94e-10	1.67e-08	219
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	38/1389	83/8135	2.68	9.54e-10	1.77e-08	83
GO:0042093	GO:0042093	T-helper cell differentiation	23/1389	37/8135	3.64	9.90e-10	1.82e-08	37
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	34/1389	70/8135	2.84	1.05e-09	1.93e-08	70
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	37/1389	80/8135	2.71	1.11e-09	2.03e-08	80
GO:0006909	GO:0006909	phagocytosis	50/1389	126/8135	2.32	1.14e-09	2.07e-08	126
GO:0002218	GO:0002218	activation of innate immune response	51/1389	130/8135	2.30	1.25e-09	2.26e-08	130
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	25/1389	43/8135	3.41	1.37e-09	2.47e-08	43
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	14/1389	16/8135	5.12	1.44e-09	2.58e-08	16
GO:0007259	GO:0007259	JAK-STAT cascade	38/1389	84/8135	2.65	1.46e-09	2.60e-08	84
GO:0032655	GO:0032655	regulation of interleukin-12 production	22/1389	35/8135	3.68	1.70e-09	3.01e-08	35
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	43/1389	102/8135	2.47	1.85e-09	3.26e-08	102
GO:0097696	GO:0097696	STAT cascade	39/1389	88/8135	2.60	1.85e-09	3.26e-08	88
GO:0007162	GO:0007162	negative regulation of cell adhesion	59/1389	162/8135	2.13	1.92e-09	3.35e-08	162
GO:0042088	GO:0042088	T-helper 1 type immune response	20/1389	30/8135	3.90	2.07e-09	3.60e-08	30
GO:0031348	GO:0031348	negative regulation of defense response	47/1389	117/8135	2.35	2.24e-09	3.88e-08	117
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	30/1389	59/8135	2.98	2.52e-09	4.35e-08	59
GO:0002637	GO:0002637	regulation of immunoglobulin production	21/1389	33/8135	3.73	2.90e-09	4.94e-08	33
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	21/1389	33/8135	3.73	2.90e-09	4.94e-08	33
GO:0046633	GO:0046633	alpha-beta T cell proliferation	17/1389	23/8135	4.33	2.92e-09	4.96e-08	23
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	76/1389	233/8135	1.91	3.24e-09	5.48e-08	233
GO:0032615	GO:0032615	interleukin-12 production	22/1389	36/8135	3.58	3.67e-09	6.14e-08	36
GO:0032653	GO:0032653	regulation of interleukin-10 production	22/1389	36/8135	3.58	3.67e-09	6.14e-08	36
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	50/1389	130/8135	2.25	4.03e-09	6.71e-08	130
GO:0032479	GO:0032479	regulation of type I interferon production	23/1389	39/8135	3.45	4.30e-09	7.11e-08	39
GO:0032606	GO:0032606	type I interferon production	23/1389	39/8135	3.45	4.30e-09	7.11e-08	39
GO:0002687	GO:0002687	positive regulation of leukocyte migration	38/1389	87/8135	2.56	4.94e-09	8.12e-08	87
GO:0048247	GO:0048247	lymphocyte chemotaxis	27/1389	51/8135	3.10	5.06e-09	8.28e-08	51
GO:0042089	GO:0042089	cytokine biosynthetic process	35/1389	77/8135	2.66	5.56e-09	9.06e-08	77
GO:0032613	GO:0032613	interleukin-10 production	22/1389	37/8135	3.48	7.59e-09	1.23e-07	37
GO:0042107	GO:0042107	cytokine metabolic process	35/1389	78/8135	2.63	8.45e-09	1.37e-07	78
GO:0002312	GO:0002312	B cell activation involved in immune response	23/1389	40/8135	3.37	8.50e-09	1.37e-07	40
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	24/1389	43/8135	3.27	9.05e-09	1.44e-07	43
GO:0045123	GO:0045123	cellular extravasation	24/1389	43/8135	3.27	9.05e-09	1.44e-07	43
GO:0050715	GO:0050715	positive regulation of cytokine secretion	38/1389	89/8135	2.50	1.06e-08	1.69e-07	89
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	20/1389	32/8135	3.66	1.10e-08	1.73e-07	32
GO:0032660	GO:0032660	regulation of interleukin-17 production	16/1389	22/8135	4.26	1.28e-08	2.02e-07	22
GO:0002698	GO:0002698	negative regulation of immune effector process	32/1389	69/8135	2.72	1.37e-08	2.15e-07	69
GO:0002260	GO:0002260	lymphocyte homeostasis	24/1389	44/8135	3.19	1.67e-08	2.61e-07	44
GO:0071216	GO:0071216	cellular response to biotic stimulus	50/1389	135/8135	2.17	1.75e-08	2.72e-07	135
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	30/1389	63/8135	2.79	1.82e-08	2.81e-07	63
GO:0006959	GO:0006959	humoral immune response	63/1389	187/8135	1.97	1.85e-08	2.85e-07	187
GO:0036336	GO:0036336	dendritic cell migration	15/1389	20/8135	4.39	1.88e-08	2.88e-07	20
GO:0051345	GO:0051345	positive regulation of hydrolase activity	102/1389	356/8135	1.68	1.95e-08	2.98e-07	356
GO:0002758	GO:0002758	innate immune response-activating signal transduction	47/1389	125/8135	2.20	2.72e-08	4.12e-07	125
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	47/1389	125/8135	2.20	2.72e-08	4.12e-07	125
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	11/1389	12/8135	5.37	3.53e-08	5.32e-07	12
GO:0032620	GO:0032620	interleukin-17 production	16/1389	23/8135	4.07	3.55e-08	5.33e-07	23
GO:0043373	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	12/1389	14/8135	5.02	3.82e-08	5.69e-07	14
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	12/1389	14/8135	5.02	3.82e-08	5.69e-07	14
GO:0097529	GO:0097529	myeloid leukocyte migration	54/1389	154/8135	2.05	4.22e-08	6.26e-07	154
GO:0006897	GO:0006897	endocytosis	101/1389	357/8135	1.66	4.66e-08	6.88e-07	357
GO:0006874	GO:0006874	cellular calcium ion homeostasis	91/1389	312/8135	1.71	4.69e-08	6.90e-07	312
GO:0070227	GO:0070227	lymphocyte apoptotic process	24/1389	46/8135	3.06	5.27e-08	7.73e-07	46
GO:0045066	GO:0045066	regulatory T cell differentiation	15/1389	21/8135	4.18	5.53e-08	8.02e-07	21
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	15/1389	21/8135	4.18	5.53e-08	8.02e-07	21
GO:0072538	GO:0072538	T-helper 17 type immune response	15/1389	21/8135	4.18	5.53e-08	8.02e-07	21
GO:0097028	GO:0097028	dendritic cell differentiation	18/1389	29/8135	3.64	7.09e-08	1.02e-06	29
GO:0072539	GO:0072539	T-helper 17 cell differentiation	14/1389	19/8135	4.32	8.35e-08	1.20e-06	19
GO:0070231	GO:0070231	T cell apoptotic process	19/1389	32/8135	3.48	8.44e-08	1.21e-06	32
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	16/1389	24/8135	3.90	8.95e-08	1.27e-06	24
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	16/1389	24/8135	3.90	8.95e-08	1.27e-06	24
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	28/1389	60/8135	2.73	9.36e-08	1.32e-06	60
GO:0032623	GO:0032623	interleukin-2 production	22/1389	41/8135	3.14	9.86e-08	1.38e-06	41
GO:0070228	GO:0070228	regulation of lymphocyte apoptotic process	22/1389	41/8135	3.14	9.86e-08	1.38e-06	41
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	34/1389	81/8135	2.46	1.05e-07	1.47e-06	81
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	79/1389	264/8135	1.75	1.13e-07	1.58e-06	264
GO:1990266	GO:1990266	neutrophil migration	38/1389	96/8135	2.32	1.22e-07	1.68e-06	96
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	26/1389	54/8135	2.82	1.23e-07	1.68e-06	54
GO:0007260	GO:0007260	tyrosine phosphorylation of STAT protein	26/1389	54/8135	2.82	1.23e-07	1.68e-06	54
GO:0038093	GO:0038093	Fc receptor signaling pathway	26/1389	54/8135	2.82	1.23e-07	1.68e-06	54
GO:0006887	GO:0006887	exocytosis	123/1389	466/8135	1.55	1.23e-07	1.68e-06	466
GO:0050691	GO:0050691	regulation of defense response to virus by host	15/1389	22/8135	3.99	1.46e-07	1.99e-06	22
GO:0002437	GO:0002437	inflammatory response to antigenic stimulus	18/1389	30/8135	3.51	1.49e-07	2.02e-06	30
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	12/1389	15/8135	4.69	1.61e-07	2.17e-06	15
GO:0002577	GO:0002577	regulation of antigen processing and presentation	12/1389	15/8135	4.69	1.61e-07	2.17e-06	15
GO:0033077	GO:0033077	T cell differentiation in thymus	22/1389	42/8135	3.07	1.74e-07	2.33e-06	42
GO:0072540	GO:0072540	T-helper 17 cell lineage commitment	10/1389	11/8135	5.32	1.91e-07	2.54e-06	11
GO:0030593	GO:0030593	neutrophil chemotaxis	36/1389	90/8135	2.34	1.92e-07	2.54e-06	90
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	36/1389	90/8135	2.34	1.92e-07	2.54e-06	90
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	36/1389	90/8135	2.34	1.92e-07	2.54e-06	90
GO:0002295	GO:0002295	T-helper cell lineage commitment	11/1389	13/8135	4.96	1.94e-07	2.55e-06	13
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	25/1389	52/8135	2.82	2.22e-07	2.92e-06	52
GO:0002714	GO:0002714	positive regulation of B cell mediated immunity	14/1389	20/8135	4.10	2.35e-07	3.06e-06	20
GO:0002891	GO:0002891	positive regulation of immunoglobulin mediated immune response	14/1389	20/8135	4.10	2.35e-07	3.06e-06	20
GO:0002573	GO:0002573	myeloid leukocyte differentiation	46/1389	129/8135	2.09	2.41e-07	3.13e-06	129
GO:0002820	GO:0002820	negative regulation of adaptive immune response	17/1389	28/8135	3.56	2.62e-07	3.38e-06	28
GO:0070232	GO:0070232	regulation of T cell apoptotic process	17/1389	28/8135	3.56	2.62e-07	3.38e-06	28
GO:0055074	GO:0055074	calcium ion homeostasis	91/1389	323/8135	1.65	2.72e-07	3.50e-06	323
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	18/1389	31/8135	3.40	2.99e-07	3.83e-06	31
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	15/1389	23/8135	3.82	3.55e-07	4.51e-06	23
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	15/1389	23/8135	3.82	3.55e-07	4.51e-06	23
GO:0072503	GO:0072503	cellular divalent inorganic cation homeostasis	93/1389	334/8135	1.63	3.60e-07	4.57e-06	334
GO:0002360	GO:0002360	T cell lineage commitment	13/1389	18/8135	4.23	3.65e-07	4.59e-06	18
GO:0002407	GO:0002407	dendritic cell chemotaxis	13/1389	18/8135	4.23	3.65e-07	4.59e-06	18
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	33/1389	81/8135	2.39	3.74e-07	4.69e-06	81
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16/1389	26/8135	3.60	4.58e-07	5.70e-06	26
GO:0042092	GO:0042092	type 2 immune response	16/1389	26/8135	3.60	4.58e-07	5.70e-06	26
GO:0046425	GO:0046425	regulation of JAK-STAT cascade	32/1389	78/8135	2.40	4.64e-07	5.76e-06	78
GO:0097530	GO:0097530	granulocyte migration	41/1389	112/8135	2.14	4.85e-07	6.00e-06	112
GO:1904892	GO:1904892	regulation of STAT cascade	33/1389	82/8135	2.36	5.24e-07	6.46e-06	82
GO:0002712	GO:0002712	regulation of B cell mediated immunity	17/1389	29/8135	3.43	5.32e-07	6.50e-06	29
GO:0002889	GO:0002889	regulation of immunoglobulin mediated immune response	17/1389	29/8135	3.43	5.32e-07	6.50e-06	29
GO:0038094	GO:0038094	Fc-gamma receptor signaling pathway	17/1389	29/8135	3.43	5.32e-07	6.50e-06	29
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	12/1389	16/8135	4.39	5.44e-07	6.62e-06	16
GO:0150076	GO:0150076	neuroinflammatory response	20/1389	38/8135	3.08	5.74e-07	6.94e-06	38
GO:0030890	GO:0030890	positive regulation of B cell proliferation	18/1389	32/8135	3.29	5.74e-07	6.94e-06	32
GO:0032640	GO:0032640	tumor necrosis factor production	34/1389	86/8135	2.32	5.81e-07	6.98e-06	86
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	34/1389	86/8135	2.32	5.81e-07	6.98e-06	86
GO:2000116	GO:2000116	regulation of cysteine-type endopeptidase activity	41/1389	113/8135	2.13	6.38e-07	7.63e-06	113
GO:0045055	GO:0045055	regulated exocytosis	111/1389	423/8135	1.54	7.20e-07	8.59e-06	423
GO:0002367	GO:0002367	cytokine production involved in immune response	28/1389	65/8135	2.52	7.36e-07	8.76e-06	65
GO:0048305	GO:0048305	immunoglobulin secretion	11/1389	14/8135	4.60	7.63e-07	9.05e-06	14
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	31/1389	76/8135	2.39	8.14e-07	9.62e-06	76
GO:0030099	GO:0030099	myeloid cell differentiation	65/1389	214/8135	1.78	8.54e-07	1.01e-05	214
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	35/1389	91/8135	2.25	8.64e-07	1.01e-05	91
GO:1904894	GO:1904894	positive regulation of STAT cascade	27/1389	62/8135	2.55	8.93e-07	1.04e-05	62
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	16/1389	27/8135	3.47	9.46e-07	1.10e-05	27
GO:0072507	GO:0072507	divalent inorganic cation homeostasis	95/1389	350/8135	1.59	9.52e-07	1.11e-05	350
GO:0002507	GO:0002507	tolerance induction	13/1389	19/8135	4.01	9.74e-07	1.12e-05	19
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	13/1389	19/8135	4.01	9.74e-07	1.12e-05	19
GO:0150077	GO:0150077	regulation of neuroinflammatory response	13/1389	19/8135	4.01	9.74e-07	1.12e-05	19
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	24/1389	52/8135	2.70	9.97e-07	1.14e-05	52
GO:0019722	GO:0019722	calcium-mediated signaling	49/1389	147/8135	1.95	1.01e-06	1.16e-05	147
GO:0002418	GO:0002418	immune response to tumor cell	9/1389	10/8135	5.27	1.02e-06	1.16e-05	10
GO:0002483	GO:0002483	antigen processing and presentation of endogenous peptide antigen	9/1389	10/8135	5.27	1.02e-06	1.16e-05	10
GO:0035458	GO:0035458	cellular response to interferon-beta	9/1389	10/8135	5.27	1.02e-06	1.16e-05	10
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	26/1389	59/8135	2.58	1.08e-06	1.22e-05	59
GO:0002828	GO:0002828	regulation of type 2 immune response	14/1389	22/8135	3.73	1.37e-06	1.54e-05	22
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	14/1389	22/8135	3.73	1.37e-06	1.54e-05	22
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	14/1389	22/8135	3.73	1.37e-06	1.54e-05	22
GO:0051090	GO:0051090	regulation of DNA-binding transcription factor activity	60/1389	195/8135	1.80	1.40e-06	1.57e-05	195
GO:0002702	GO:0002702	positive regulation of production of molecular mediator of immune response	24/1389	53/8135	2.65	1.53e-06	1.70e-05	53
GO:0071674	GO:0071674	mononuclear cell migration	28/1389	67/8135	2.45	1.55e-06	1.72e-05	67
GO:0032480	GO:0032480	negative regulation of type I interferon production	12/1389	17/8135	4.13	1.56e-06	1.72e-05	17
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	12/1389	17/8135	4.13	1.56e-06	1.72e-05	17
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	15/1389	25/8135	3.51	1.68e-06	1.83e-05	25
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	15/1389	25/8135	3.51	1.68e-06	1.83e-05	25
GO:0070229	GO:0070229	negative regulation of lymphocyte apoptotic process	15/1389	25/8135	3.51	1.68e-06	1.83e-05	25
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	22/1389	47/8135	2.74	2.10e-06	2.28e-05	47
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	22/1389	47/8135	2.74	2.10e-06	2.28e-05	47
GO:0010818	GO:0010818	T cell chemotaxis	13/1389	20/8135	3.81	2.35e-06	2.54e-05	20
GO:0050869	GO:0050869	negative regulation of B cell activation	13/1389	20/8135	3.81	2.35e-06	2.54e-05	20
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	11/1389	15/8135	4.29	2.42e-06	2.59e-05	15
GO:0042832	GO:0042832	defense response to protozoan	11/1389	15/8135	4.29	2.42e-06	2.59e-05	15
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	11/1389	15/8135	4.29	2.42e-06	2.59e-05	15
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	20/1389	41/8135	2.86	2.73e-06	2.92e-05	41
GO:0071621	GO:0071621	granulocyte chemotaxis	37/1389	103/8135	2.10	2.94e-06	3.12e-05	103
GO:0002639	GO:0002639	positive regulation of immunoglobulin production	14/1389	23/8135	3.56	2.96e-06	3.12e-05	23
GO:0032481	GO:0032481	positive regulation of type I interferon production	14/1389	23/8135	3.56	2.96e-06	3.12e-05	23
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	14/1389	23/8135	3.56	2.96e-06	3.12e-05	23
GO:0032663	GO:0032663	regulation of interleukin-2 production	18/1389	35/8135	3.01	3.29e-06	3.45e-05	35
GO:0043030	GO:0043030	regulation of macrophage activation	18/1389	35/8135	3.01	3.29e-06	3.45e-05	35
GO:0002369	GO:0002369	T cell cytokine production	15/1389	26/8135	3.38	3.34e-06	3.49e-05	26
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	17/1389	32/8135	3.11	3.46e-06	3.60e-05	32
GO:0061900	GO:0061900	glial cell activation	17/1389	32/8135	3.11	3.46e-06	3.60e-05	32
GO:0002431	GO:0002431	Fc receptor mediated stimulatory signaling pathway	16/1389	29/8135	3.23	3.49e-06	3.62e-05	29
GO:0006875	GO:0006875	cellular metal ion homeostasis	98/1389	374/8135	1.53	3.53e-06	3.65e-05	374
GO:0032740	GO:0032740	positive regulation of interleukin-17 production	10/1389	13/8135	4.51	3.55e-06	3.65e-05	13
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	10/1389	13/8135	4.51	3.55e-06	3.65e-05	13
GO:0050921	GO:0050921	positive regulation of chemotaxis	34/1389	92/8135	2.16	3.56e-06	3.65e-05	92
GO:0002335	GO:0002335	mature B cell differentiation	12/1389	18/8135	3.90	3.96e-06	4.01e-05	18
GO:0002832	GO:0002832	negative regulation of response to biotic stimulus	12/1389	18/8135	3.90	3.96e-06	4.01e-05	18
GO:0070233	GO:0070233	negative regulation of T cell apoptotic process	12/1389	18/8135	3.90	3.96e-06	4.01e-05	18
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	12/1389	18/8135	3.90	3.96e-06	4.01e-05	18
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	28/1389	70/8135	2.34	4.36e-06	4.41e-05	70
GO:0030335	GO:0030335	positive regulation of cell migration	79/1389	287/8135	1.61	4.49e-06	4.53e-05	287
GO:0018108	GO:0018108	peptidyl-tyrosine phosphorylation	68/1389	237/8135	1.68	4.52e-06	4.53e-05	237
GO:0018212	GO:0018212	peptidyl-tyrosine modification	68/1389	237/8135	1.68	4.52e-06	4.53e-05	237
GO:0070555	GO:0070555	response to interleukin-1	33/1389	89/8135	2.17	4.54e-06	4.53e-05	89
GO:0090087	GO:0090087	regulation of peptide transport	98/1389	376/8135	1.53	4.54e-06	4.53e-05	376
GO:0043011	GO:0043011	myeloid dendritic cell differentiation	9/1389	11/8135	4.79	4.77e-06	4.74e-05	11
GO:0002790	GO:0002790	peptide secretion	96/1389	367/8135	1.53	4.82e-06	4.79e-05	367
GO:0051223	GO:0051223	regulation of protein transport	93/1389	353/8135	1.54	4.94e-06	4.89e-05	353
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	22/1389	49/8135	2.63	4.96e-06	4.90e-05	49
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	13/1389	21/8135	3.63	5.20e-06	5.12e-05	21
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	23/1389	53/8135	2.54	6.16e-06	6.01e-05	53
GO:0042116	GO:0042116	macrophage activation	23/1389	53/8135	2.54	6.16e-06	6.01e-05	53
GO:0002381	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	15/1389	27/8135	3.25	6.33e-06	6.16e-05	27
GO:0001562	GO:0001562	response to protozoan	11/1389	16/8135	4.03	6.54e-06	6.35e-05	16
GO:0046718	GO:0046718	viral entry into host cell	26/1389	64/8135	2.38	6.81e-06	6.59e-05	64
GO:0050710	GO:0050710	negative regulation of cytokine secretion	20/1389	43/8135	2.72	6.89e-06	6.65e-05	43
GO:0002791	GO:0002791	regulation of peptide secretion	82/1389	305/8135	1.57	7.95e-06	7.65e-05	305
GO:0070374	GO:0070374	positive regulation of ERK1 and ERK2 cascade	53/1389	174/8135	1.78	7.96e-06	7.65e-05	174
GO:0070201	GO:0070201	regulation of establishment of protein localization	94/1389	362/8135	1.52	8.42e-06	8.07e-05	362
GO:0043068	GO:0043068	positive regulation of programmed cell death	78/1389	287/8135	1.59	8.63e-06	8.24e-05	287
GO:0010942	GO:0010942	positive regulation of cell death	85/1389	320/8135	1.56	9.03e-06	8.61e-05	320
GO:0050856	GO:0050856	regulation of T cell receptor signaling pathway	12/1389	19/8135	3.70	9.07e-06	8.62e-05	19
GO:0010950	GO:0010950	positive regulation of endopeptidase activity	30/1389	80/8135	2.20	9.40e-06	8.91e-05	80
GO:0050708	GO:0050708	regulation of protein secretion	77/1389	283/8135	1.59	9.42e-06	8.91e-05	283
GO:0032612	GO:0032612	interleukin-1 production	26/1389	65/8135	2.34	9.53e-06	8.99e-05	65
GO:2000147	GO:2000147	positive regulation of cell motility	81/1389	302/8135	1.57	9.95e-06	9.36e-05	302
GO:0010952	GO:0010952	positive regulation of peptidase activity	32/1389	88/8135	2.13	1.01e-05	9.50e-05	88
GO:0009306	GO:0009306	protein secretion	89/1389	340/8135	1.53	1.04e-05	9.75e-05	340
GO:0002224	GO:0002224	toll-like receptor signaling pathway	27/1389	69/8135	2.29	1.05e-05	9.75e-05	69
GO:2001056	GO:2001056	positive regulation of cysteine-type endopeptidase activity	27/1389	69/8135	2.29	1.05e-05	9.75e-05	69
GO:0046596	GO:0046596	regulation of viral entry into host cell	10/1389	14/8135	4.18	1.05e-05	9.77e-05	14
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	20/1389	44/8135	2.66	1.06e-05	9.84e-05	44
GO:0050901	GO:0050901	leukocyte tethering or rolling	13/1389	22/8135	3.46	1.07e-05	9.91e-05	22
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	22/1389	51/8135	2.53	1.10e-05	1.01e-04	51
GO:0030162	GO:0030162	regulation of proteolysis	96/1389	374/8135	1.50	1.13e-05	1.04e-04	374
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	14/1389	25/8135	3.28	1.15e-05	1.05e-04	25
GO:0045581	GO:0045581	negative regulation of T cell differentiation	14/1389	25/8135	3.28	1.15e-05	1.05e-04	25
GO:0032633	GO:0032633	interleukin-4 production	15/1389	28/8135	3.14	1.15e-05	1.05e-04	28
GO:0046006	GO:0046006	regulation of activated T cell proliferation	15/1389	28/8135	3.14	1.15e-05	1.05e-04	28
GO:0050920	GO:0050920	regulation of chemotaxis	46/1389	146/8135	1.85	1.19e-05	1.08e-04	146
GO:0043065	GO:0043065	positive regulation of apoptotic process	77/1389	285/8135	1.58	1.24e-05	1.12e-04	285
GO:0050701	GO:0050701	interleukin-1 secretion	19/1389	41/8135	2.71	1.25e-05	1.13e-04	41
GO:0043547	GO:0043547	positive regulation of GTPase activity	54/1389	181/8135	1.75	1.28e-05	1.15e-04	181
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	23/1389	55/8135	2.45	1.30e-05	1.16e-04	55
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	23/1389	55/8135	2.45	1.30e-05	1.16e-04	55
GO:0043281	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	34/1389	97/8135	2.05	1.35e-05	1.21e-04	97
GO:2000401	GO:2000401	regulation of lymphocyte migration	18/1389	38/8135	2.77	1.45e-05	1.29e-04	38
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	11/1389	17/8135	3.79	1.57e-05	1.39e-04	17
GO:0042742	GO:0042742	defense response to bacterium	48/1389	156/8135	1.80	1.57e-05	1.39e-04	156
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	22/1389	52/8135	2.48	1.60e-05	1.41e-04	52
GO:0035455	GO:0035455	response to interferon-alpha	9/1389	12/8135	4.39	1.62e-05	1.41e-04	12
GO:0051023	GO:0051023	regulation of immunoglobulin secretion	9/1389	12/8135	4.39	1.62e-05	1.41e-04	12
GO:1903978	GO:1903978	regulation of microglial cell activation	9/1389	12/8135	4.39	1.62e-05	1.41e-04	12
GO:0050702	GO:0050702	interleukin-1 beta secretion	17/1389	35/8135	2.84	1.65e-05	1.44e-04	35
GO:0051272	GO:0051272	positive regulation of cellular component movement	82/1389	311/8135	1.54	1.75e-05	1.52e-04	311
GO:0030260	GO:0030260	entry into host cell	26/1389	67/8135	2.27	1.81e-05	1.56e-04	67
GO:0044409	GO:0044409	entry into host	26/1389	67/8135	2.27	1.81e-05	1.56e-04	67
GO:0051806	GO:0051806	entry into cell of other organism involved in symbiotic interaction	26/1389	67/8135	2.27	1.81e-05	1.56e-04	67
GO:0051828	GO:0051828	entry into other organism involved in symbiotic interaction	26/1389	67/8135	2.27	1.81e-05	1.56e-04	67
GO:0002920	GO:0002920	regulation of humoral immune response	23/1389	56/8135	2.41	1.86e-05	1.60e-04	56
GO:0070372	GO:0070372	regulation of ERK1 and ERK2 cascade	62/1389	219/8135	1.66	1.88e-05	1.61e-04	219
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	12/1389	20/8135	3.51	1.92e-05	1.64e-04	20
GO:1902624	GO:1902624	positive regulation of neutrophil migration	12/1389	20/8135	3.51	1.92e-05	1.64e-04	20
GO:0006911	GO:0006911	phagocytosis, engulfment	15/1389	29/8135	3.03	2.01e-05	1.71e-04	29
GO:0050798	GO:0050798	activated T cell proliferation	15/1389	29/8135	3.03	2.01e-05	1.71e-04	29
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	13/1389	23/8135	3.31	2.08e-05	1.76e-04	23
GO:0001774	GO:0001774	microglial cell activation	14/1389	26/8135	3.15	2.10e-05	1.76e-04	26
GO:0002200	GO:0002200	somatic diversification of immune receptors	14/1389	26/8135	3.15	2.10e-05	1.76e-04	26
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	14/1389	26/8135	3.15	2.10e-05	1.76e-04	26
GO:0002433	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	14/1389	26/8135	3.15	2.10e-05	1.76e-04	26
GO:0038096	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	14/1389	26/8135	3.15	2.10e-05	1.76e-04	26
GO:0060402	GO:0060402	calcium ion transport into cytosol	35/1389	103/8135	1.99	2.19e-05	1.83e-04	103
GO:0050728	GO:0050728	negative regulation of inflammatory response	31/1389	87/8135	2.09	2.22e-05	1.85e-04	87
GO:0001771	GO:0001771	immunological synapse formation	8/1389	10/8135	4.69	2.30e-05	1.91e-04	10
GO:0001911	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	8/1389	10/8135	4.69	2.30e-05	1.91e-04	10
GO:2001185	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	8/1389	10/8135	4.69	2.30e-05	1.91e-04	10
GO:0032102	GO:0032102	negative regulation of response to external stimulus	59/1389	207/8135	1.67	2.39e-05	1.98e-04	207
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	46/1389	150/8135	1.80	2.58e-05	2.13e-04	150
GO:0032652	GO:0032652	regulation of interleukin-1 production	23/1389	57/8135	2.36	2.61e-05	2.15e-04	57
GO:0040017	GO:0040017	positive regulation of locomotion	83/1389	319/8135	1.52	2.64e-05	2.17e-04	319
GO:0002313	GO:0002313	mature B cell differentiation involved in immune response	10/1389	15/8135	3.90	2.67e-05	2.18e-04	15
GO:0045061	GO:0045061	thymic T cell selection	10/1389	15/8135	3.90	2.67e-05	2.18e-04	15
GO:2000316	GO:2000316	regulation of T-helper 17 type immune response	10/1389	15/8135	3.90	2.67e-05	2.18e-04	15
GO:0060401	GO:0060401	cytosolic calcium ion transport	35/1389	104/8135	1.97	2.77e-05	2.25e-04	104
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	19/1389	43/8135	2.59	2.89e-05	2.35e-04	43
GO:0002548	GO:0002548	monocyte chemotaxis	22/1389	54/8135	2.39	3.27e-05	2.63e-04	54
GO:0032611	GO:0032611	interleukin-1 beta production	22/1389	54/8135	2.39	3.27e-05	2.63e-04	54
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	11/1389	18/8135	3.58	3.41e-05	2.72e-04	18
GO:0035743	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	11/1389	18/8135	3.58	3.41e-05	2.72e-04	18
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	11/1389	18/8135	3.58	3.41e-05	2.72e-04	18
GO:1901623	GO:1901623	regulation of lymphocyte chemotaxis	11/1389	18/8135	3.58	3.41e-05	2.72e-04	18
GO:0006919	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	18/1389	40/8135	2.64	3.47e-05	2.76e-04	40
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	18/1389	40/8135	2.64	3.47e-05	2.76e-04	40
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	28/1389	77/8135	2.13	3.58e-05	2.83e-04	77
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	28/1389	77/8135	2.13	3.58e-05	2.83e-04	77
GO:0045824	GO:0045824	negative regulation of innate immune response	14/1389	27/8135	3.04	3.68e-05	2.90e-04	27
GO:2000404	GO:2000404	regulation of T cell migration	14/1389	27/8135	3.04	3.68e-05	2.90e-04	27
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	39/1389	122/8135	1.87	3.74e-05	2.94e-04	122
GO:0052548	GO:0052548	regulation of endopeptidase activity	66/1389	242/8135	1.60	3.75e-05	2.95e-04	242
GO:0070670	GO:0070670	response to interleukin-4	12/1389	21/8135	3.35	3.78e-05	2.96e-04	21
GO:0002562	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	13/1389	24/8135	3.17	3.84e-05	2.98e-04	24
GO:0009164	GO:0009164	nucleoside catabolic process	13/1389	24/8135	3.17	3.84e-05	2.98e-04	24
GO:0016444	GO:0016444	somatic cell DNA recombination	13/1389	24/8135	3.17	3.84e-05	2.98e-04	24
GO:0032673	GO:0032673	regulation of interleukin-4 production	13/1389	24/8135	3.17	3.84e-05	2.98e-04	24
GO:0070371	GO:0070371	ERK1 and ERK2 cascade	63/1389	229/8135	1.61	4.22e-05	3.27e-04	229
GO:0002710	GO:0002710	negative regulation of T cell mediated immunity	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:0002830	GO:0002830	positive regulation of type 2 immune response	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:0006925	GO:0006925	inflammatory cell apoptotic process	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:0050858	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:0150078	GO:0150078	positive regulation of neuroinflammatory response	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:2000319	GO:2000319	regulation of T-helper 17 cell differentiation	9/1389	13/8135	4.05	4.45e-05	3.41e-04	13
GO:0002673	GO:0002673	regulation of acute inflammatory response	27/1389	74/8135	2.14	4.59e-05	3.50e-04	74
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	28/1389	78/8135	2.10	4.69e-05	3.57e-04	78
GO:0002526	GO:0002526	acute inflammatory response	38/1389	119/8135	1.87	4.81e-05	3.66e-04	119
GO:0052547	GO:0052547	regulation of peptidase activity	69/1389	258/8135	1.57	4.97e-05	3.77e-04	258
GO:0010324	GO:0010324	membrane invagination	15/1389	31/8135	2.83	5.53e-05	4.18e-04	31
GO:0099024	GO:0099024	plasma membrane invagination	15/1389	31/8135	2.83	5.53e-05	4.18e-04	31
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	10/1389	16/8135	3.66	6.03e-05	4.54e-04	16
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	10/1389	16/8135	3.66	6.03e-05	4.54e-04	16
GO:0051208	GO:0051208	sequestering of calcium ion	28/1389	79/8135	2.08	6.10e-05	4.58e-04	79
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	17/1389	38/8135	2.62	6.27e-05	4.70e-04	38
GO:0043029	GO:0043029	T cell homeostasis	13/1389	25/8135	3.05	6.75e-05	5.04e-04	25
GO:0043277	GO:0043277	apoptotic cell clearance	13/1389	25/8135	3.05	6.75e-05	5.04e-04	25
GO:0001782	GO:0001782	B cell homeostasis	11/1389	19/8135	3.39	6.85e-05	5.06e-04	19
GO:0002474	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	11/1389	19/8135	3.39	6.85e-05	5.06e-04	19
GO:0042104	GO:0042104	positive regulation of activated T cell proliferation	11/1389	19/8135	3.39	6.85e-05	5.06e-04	19
GO:0071353	GO:0071353	cellular response to interleukin-4	11/1389	19/8135	3.39	6.85e-05	5.06e-04	19
GO:2000406	GO:2000406	positive regulation of T cell migration	11/1389	19/8135	3.39	6.85e-05	5.06e-04	19
GO:0016445	GO:0016445	somatic diversification of immunoglobulins	12/1389	22/8135	3.19	7.02e-05	5.17e-04	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	12/1389	22/8135	3.19	7.02e-05	5.17e-04	22
GO:0010819	GO:0010819	regulation of T cell chemotaxis	8/1389	11/8135	4.26	7.18e-05	5.23e-04	11
GO:0031342	GO:0031342	negative regulation of cell killing	8/1389	11/8135	4.26	7.18e-05	5.23e-04	11
GO:0043383	GO:0043383	negative T cell selection	8/1389	11/8135	4.26	7.18e-05	5.23e-04	11
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	8/1389	11/8135	4.26	7.18e-05	5.23e-04	11
GO:0046629	GO:0046629	gamma-delta T cell activation	8/1389	11/8135	4.26	7.18e-05	5.23e-04	11
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	16/1389	35/8135	2.68	7.47e-05	5.43e-04	35
GO:0050709	GO:0050709	negative regulation of protein secretion	27/1389	76/8135	2.08	7.84e-05	5.69e-04	76
GO:0045620	GO:0045620	negative regulation of lymphocyte differentiation	15/1389	32/8135	2.75	8.77e-05	6.33e-04	32
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	15/1389	32/8135	2.75	8.77e-05	6.33e-04	32
GO:0032651	GO:0032651	regulation of interleukin-1 beta production	19/1389	46/8135	2.42	8.95e-05	6.44e-04	46
GO:0045862	GO:0045862	positive regulation of proteolysis	43/1389	144/8135	1.75	9.34e-05	6.71e-04	144
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	24/1389	65/8135	2.16	9.63e-05	6.91e-04	65
GO:0050706	GO:0050706	regulation of interleukin-1 beta secretion	14/1389	29/8135	2.83	1.01e-04	7.24e-04	29
GO:0045072	GO:0045072	regulation of interferon-gamma biosynthetic process	9/1389	14/8135	3.77	1.06e-04	7.56e-04	14
GO:0051224	GO:0051224	negative regulation of protein transport	31/1389	94/8135	1.93	1.20e-04	8.55e-04	94
GO:0002544	GO:0002544	chronic inflammatory response	10/1389	17/8135	3.45	1.24e-04	8.79e-04	17
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	10/1389	17/8135	3.45	1.24e-04	8.79e-04	17
GO:0002204	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0002208	GO:0002208	somatic diversification of immunoglobulins involved in immune response	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0016447	GO:0016447	somatic recombination of immunoglobulin gene segments	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0032814	GO:0032814	regulation of natural killer cell activation	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0033028	GO:0033028	myeloid cell apoptotic process	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0043032	GO:0043032	positive regulation of macrophage activation	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0045190	GO:0045190	isotype switching	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0046135	GO:0046135	pyrimidine nucleoside catabolic process	11/1389	20/8135	3.22	1.29e-04	8.99e-04	20
GO:0097191	GO:0097191	extrinsic apoptotic signaling pathway	34/1389	107/8135	1.86	1.32e-04	9.19e-04	107
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	17/1389	40/8135	2.49	1.37e-04	9.53e-04	40
GO:1904950	GO:1904950	negative regulation of establishment of protein localization	31/1389	95/8135	1.91	1.50e-04	1.04e-03	95
GO:0032715	GO:0032715	negative regulation of interleukin-6 production	14/1389	30/8135	2.73	1.60e-04	1.11e-03	30
GO:0002792	GO:0002792	negative regulation of peptide secretion	28/1389	83/8135	1.98	1.63e-04	1.13e-03	83
GO:0002793	GO:0002793	positive regulation of peptide secretion	50/1389	179/8135	1.64	1.70e-04	1.17e-03	179
GO:0043087	GO:0043087	regulation of GTPase activity	58/1389	216/8135	1.57	1.73e-04	1.19e-03	216
GO:0051222	GO:0051222	positive regulation of protein transport	58/1389	216/8135	1.57	1.73e-04	1.19e-03	216
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	8/1389	12/8135	3.90	1.83e-04	1.25e-03	12
GO:1901658	GO:1901658	glycosyl compound catabolic process	13/1389	27/8135	2.82	1.86e-04	1.27e-03	27
GO:0002686	GO:0002686	negative regulation of leukocyte migration	15/1389	34/8135	2.58	2.05e-04	1.39e-03	34
GO:0030224	GO:0030224	monocyte differentiation	12/1389	24/8135	2.93	2.10e-04	1.42e-03	24
GO:1902622	GO:1902622	regulation of neutrophil migration	12/1389	24/8135	2.93	2.10e-04	1.42e-03	24
GO:1903131	GO:1903131	mononuclear cell differentiation	12/1389	24/8135	2.93	2.10e-04	1.42e-03	24
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	12/1389	24/8135	2.93	2.10e-04	1.42e-03	24
GO:0071347	GO:0071347	cellular response to interleukin-1	26/1389	76/8135	2.00	2.14e-04	1.44e-03	76
GO:0031334	GO:0031334	positive regulation of protein complex assembly	32/1389	101/8135	1.86	2.18e-04	1.47e-03	101
GO:0001779	GO:0001779	natural killer cell differentiation	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0002347	GO:0002347	response to tumor cell	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0032607	GO:0032607	interferon-alpha production	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0033622	GO:0033622	integrin activation	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0042095	GO:0042095	interferon-gamma biosynthetic process	9/1389	15/8135	3.51	2.24e-04	1.49e-03	15
GO:0043552	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	11/1389	21/8135	3.07	2.29e-04	1.51e-03	21
GO:1904951	GO:1904951	positive regulation of establishment of protein localization	59/1389	223/8135	1.55	2.35e-04	1.55e-03	223
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	10/1389	18/8135	3.25	2.37e-04	1.55e-03	18
GO:0030866	GO:0030866	cortical actin cytoskeleton organization	10/1389	18/8135	3.25	2.37e-04	1.55e-03	18
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	10/1389	18/8135	3.25	2.37e-04	1.55e-03	18
GO:0045577	GO:0045577	regulation of B cell differentiation	10/1389	18/8135	3.25	2.37e-04	1.55e-03	18
GO:0032088	GO:0032088	negative regulation of NF-kappaB transcription factor activity	14/1389	31/8135	2.64	2.47e-04	1.61e-03	31
GO:0006898	GO:0006898	receptor-mediated endocytosis	49/1389	177/8135	1.62	2.48e-04	1.62e-03	177
GO:0051701	GO:0051701	interaction with host	28/1389	85/8135	1.93	2.58e-04	1.68e-03	85
GO:0043280	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	21/1389	57/8135	2.16	2.69e-04	1.75e-03	57
GO:0050714	GO:0050714	positive regulation of protein secretion	46/1389	164/8135	1.64	2.75e-04	1.79e-03	164
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	24/1389	69/8135	2.04	2.79e-04	1.81e-03	69
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	13/1389	28/8135	2.72	2.93e-04	1.89e-03	28
GO:0034656	GO:0034656	nucleobase-containing small molecule catabolic process	13/1389	28/8135	2.72	2.93e-04	1.89e-03	28
GO:0042130	GO:0042130	negative regulation of T cell proliferation	15/1389	35/8135	2.51	3.02e-04	1.94e-03	35
GO:0043550	GO:0043550	regulation of lipid kinase activity	15/1389	35/8135	2.51	3.02e-04	1.94e-03	35
GO:0009116	GO:0009116	nucleoside metabolic process	18/1389	46/8135	2.29	3.08e-04	1.96e-03	46
GO:0010820	GO:0010820	positive regulation of T cell chemotaxis	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0035745	GO:0035745	T-helper 2 cell cytokine production	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0035747	GO:0035747	natural killer cell chemotaxis	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0045060	GO:0045060	negative thymic T cell selection	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0045063	GO:0045063	T-helper 1 cell differentiation	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0045078	GO:0045078	positive regulation of interferon-gamma biosynthetic process	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0045591	GO:0045591	positive regulation of regulatory T cell differentiation	7/1389	10/8135	4.10	3.10e-04	1.96e-03	10
GO:0002534	GO:0002534	cytokine production involved in inflammatory response	12/1389	25/8135	2.81	3.41e-04	2.15e-03	25
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	12/1389	25/8135	2.81	3.41e-04	2.15e-03	25
GO:0050766	GO:0050766	positive regulation of phagocytosis	16/1389	39/8135	2.40	3.50e-04	2.20e-03	39
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	14/1389	32/8135	2.56	3.70e-04	2.32e-03	32
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	14/1389	32/8135	2.56	3.70e-04	2.32e-03	32
GO:0032635	GO:0032635	interleukin-6 production	29/1389	91/8135	1.87	3.80e-04	2.37e-03	91
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	29/1389	91/8135	1.87	3.80e-04	2.37e-03	91
GO:0032692	GO:0032692	negative regulation of interleukin-1 production	11/1389	22/8135	2.93	3.87e-04	2.41e-03	22
GO:0098586	GO:0098586	cellular response to virus	11/1389	22/8135	2.93	3.87e-04	2.41e-03	22
GO:0002643	GO:0002643	regulation of tolerance induction	8/1389	13/8135	3.60	4.05e-04	2.51e-03	13
GO:0033033	GO:0033033	negative regulation of myeloid cell apoptotic process	8/1389	13/8135	3.60	4.05e-04	2.51e-03	13
GO:0045637	GO:0045637	regulation of myeloid cell differentiation	39/1389	135/8135	1.69	4.11e-04	2.55e-03	135
GO:0002719	GO:0002719	negative regulation of cytokine production involved in immune response	10/1389	19/8135	3.08	4.23e-04	2.60e-03	19
GO:0002724	GO:0002724	regulation of T cell cytokine production	10/1389	19/8135	3.08	4.23e-04	2.60e-03	19
GO:0002753	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	10/1389	19/8135	3.08	4.23e-04	2.60e-03	19
GO:0033032	GO:0033032	regulation of myeloid cell apoptotic process	10/1389	19/8135	3.08	4.23e-04	2.60e-03	19
GO:0060142	GO:0060142	regulation of syncytium formation by plasma membrane fusion	10/1389	19/8135	3.08	4.23e-04	2.60e-03	19
GO:0034103	GO:0034103	regulation of tissue remodeling	19/1389	51/8135	2.18	4.42e-04	2.70e-03	51
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	25/1389	75/8135	1.95	4.43e-04	2.70e-03	75
GO:0070613	GO:0070613	regulation of protein processing	25/1389	75/8135	1.95	4.43e-04	2.70e-03	75
GO:1903727	GO:1903727	positive regulation of phospholipid metabolic process	13/1389	29/8135	2.63	4.48e-04	2.73e-03	29
GO:0006956	GO:0006956	complement activation	20/1389	55/8135	2.13	4.56e-04	2.77e-03	55
GO:0051048	GO:0051048	negative regulation of secretion	41/1389	145/8135	1.66	4.83e-04	2.93e-03	145
GO:0030449	GO:0030449	regulation of complement activation	16/1389	40/8135	2.34	4.92e-04	2.99e-03	40
GO:1903531	GO:1903531	negative regulation of secretion by cell	36/1389	123/8135	1.71	5.16e-04	3.12e-03	123
GO:1903725	GO:1903725	regulation of phospholipid metabolic process	17/1389	44/8135	2.26	5.35e-04	3.23e-03	44
GO:1903317	GO:1903317	regulation of protein maturation	25/1389	76/8135	1.93	5.55e-04	3.35e-03	76
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	37/1389	128/8135	1.69	5.65e-04	3.41e-03	128
GO:0002220	GO:0002220	innate immune response activating cell surface receptor signaling pathway	15/1389	37/8135	2.37	6.21e-04	3.73e-03	37
GO:0002532	GO:0002532	production of molecular mediator involved in inflammatory response	15/1389	37/8135	2.37	6.21e-04	3.73e-03	37
GO:0045730	GO:0045730	respiratory burst	11/1389	23/8135	2.80	6.29e-04	3.76e-03	23
GO:0090218	GO:0090218	positive regulation of lipid kinase activity	11/1389	23/8135	2.80	6.29e-04	3.76e-03	23
GO:0032675	GO:0032675	regulation of interleukin-6 production	27/1389	85/8135	1.86	6.32e-04	3.78e-03	85
GO:0002720	GO:0002720	positive regulation of cytokine production involved in immune response	13/1389	30/8135	2.54	6.69e-04	3.99e-03	30
GO:2000257	GO:2000257	regulation of protein activation cascade	16/1389	41/8135	2.29	6.81e-04	4.06e-03	41
GO:0030865	GO:0030865	cortical cytoskeleton organization	10/1389	20/8135	2.93	7.18e-04	4.27e-03	20
GO:0032816	GO:0032816	positive regulation of natural killer cell activation	7/1389	11/8135	3.73	7.26e-04	4.29e-03	11
GO:0043371	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	7/1389	11/8135	3.73	7.26e-04	4.29e-03	11
GO:0043374	GO:0043374	CD8-positive, alpha-beta T cell differentiation	7/1389	11/8135	3.73	7.26e-04	4.29e-03	11
GO:0050711	GO:0050711	negative regulation of interleukin-1 secretion	7/1389	11/8135	3.73	7.26e-04	4.29e-03	11
GO:0002262	GO:0002262	myeloid cell homeostasis	21/1389	61/8135	2.02	7.70e-04	4.54e-03	61
GO:2000108	GO:2000108	positive regulation of leukocyte apoptotic process	9/1389	17/8135	3.10	7.86e-04	4.63e-03	17
GO:0045191	GO:0045191	regulation of isotype switching	8/1389	14/8135	3.35	8.03e-04	4.71e-03	14
GO:0140131	GO:0140131	positive regulation of lymphocyte chemotaxis	8/1389	14/8135	3.35	8.03e-04	4.71e-03	14
GO:1901739	GO:1901739	regulation of myoblast fusion	8/1389	14/8135	3.35	8.03e-04	4.71e-03	14
GO:0030100	GO:0030100	regulation of endocytosis	37/1389	131/8135	1.65	9.13e-04	5.33e-03	131
GO:0006213	GO:0006213	pyrimidine nucleoside metabolic process	11/1389	24/8135	2.68	9.83e-04	5.73e-03	24
GO:0072529	GO:0072529	pyrimidine-containing compound catabolic process	11/1389	24/8135	2.68	9.83e-04	5.73e-03	24
GO:0045639	GO:0045639	positive regulation of myeloid cell differentiation	19/1389	54/8135	2.06	1.00e-03	5.82e-03	54
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	12/1389	28/8135	2.51	1.21e-03	7.02e-03	28
GO:0048771	GO:0048771	tissue remodeling	31/1389	106/8135	1.71	1.24e-03	7.21e-03	106
GO:0002438	GO:0002438	acute inflammatory response to antigenic stimulus	9/1389	18/8135	2.93	1.33e-03	7.70e-03	18
GO:0033081	GO:0033081	regulation of T cell differentiation in thymus	9/1389	18/8135	2.93	1.33e-03	7.70e-03	18
GO:0060143	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	9/1389	18/8135	2.93	1.33e-03	7.70e-03	18
GO:0033628	GO:0033628	regulation of cell adhesion mediated by integrin	13/1389	32/8135	2.38	1.39e-03	7.99e-03	32
GO:0043433	GO:0043433	negative regulation of DNA-binding transcription factor activity	23/1389	72/8135	1.87	1.43e-03	8.20e-03	72
GO:0046639	GO:0046639	negative regulation of alpha-beta T cell differentiation	8/1389	15/8135	3.12	1.46e-03	8.41e-03	15
GO:0002726	GO:0002726	positive regulation of T cell cytokine production	7/1389	12/8135	3.42	1.49e-03	8.47e-03	12
GO:0045655	GO:0045655	regulation of monocyte differentiation	7/1389	12/8135	3.42	1.49e-03	8.47e-03	12
GO:1904994	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	7/1389	12/8135	3.42	1.49e-03	8.47e-03	12
GO:0007520	GO:0007520	myoblast fusion	11/1389	25/8135	2.58	1.49e-03	8.47e-03	25
GO:0072677	GO:0072677	eosinophil migration	11/1389	25/8135	2.58	1.49e-03	8.47e-03	25
GO:0002763	GO:0002763	positive regulation of myeloid leukocyte differentiation	14/1389	36/8135	2.28	1.52e-03	8.62e-03	36
GO:0002886	GO:0002886	regulation of myeloid leukocyte mediated immunity	14/1389	36/8135	2.28	1.52e-03	8.62e-03	36
GO:0045807	GO:0045807	positive regulation of endocytosis	25/1389	81/8135	1.81	1.56e-03	8.87e-03	81
GO:0050848	GO:0050848	regulation of calcium-mediated signaling	20/1389	60/8135	1.95	1.60e-03	9.06e-03	60
GO:0010524	GO:0010524	positive regulation of calcium ion transport into cytosol	15/1389	40/8135	2.20	1.60e-03	9.06e-03	40
GO:0032722	GO:0032722	positive regulation of chemokine production	15/1389	40/8135	2.20	1.60e-03	9.06e-03	40
GO:0033627	GO:0033627	cell adhesion mediated by integrin	17/1389	48/8135	2.07	1.67e-03	9.43e-03	48
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	12/1389	29/8135	2.42	1.75e-03	9.81e-03	29
GO:0051482	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	12/1389	29/8135	2.42	1.75e-03	9.81e-03	29
GO:0050718	GO:0050718	positive regulation of interleukin-1 beta secretion	10/1389	22/8135	2.66	1.81e-03	1.01e-02	22
GO:0000768	GO:0000768	syncytium formation by plasma membrane fusion	13/1389	33/8135	2.31	1.94e-03	1.08e-02	33
GO:0006949	GO:0006949	syncytium formation	13/1389	33/8135	2.31	1.94e-03	1.08e-02	33
GO:0032732	GO:0032732	positive regulation of interleukin-1 production	13/1389	33/8135	2.31	1.94e-03	1.08e-02	33
GO:0140253	GO:0140253	cell-cell fusion	13/1389	33/8135	2.31	1.94e-03	1.08e-02	33
GO:0030168	GO:0030168	platelet activation	29/1389	100/8135	1.70	2.03e-03	1.12e-02	100
GO:0002244	GO:0002244	hematopoietic progenitor cell differentiation	18/1389	53/8135	1.99	2.13e-03	1.18e-02	53
GO:0045576	GO:0045576	mast cell activation	16/1389	45/8135	2.08	2.17e-03	1.20e-02	45
GO:0050716	GO:0050716	positive regulation of interleukin-1 secretion	11/1389	26/8135	2.48	2.19e-03	1.21e-02	26
GO:0043300	GO:0043300	regulation of leukocyte degranulation	12/1389	30/8135	2.34	2.46e-03	1.36e-02	30
GO:0032691	GO:0032691	negative regulation of interleukin-1 beta production	8/1389	16/8135	2.93	2.49e-03	1.37e-02	16
GO:0042454	GO:0042454	ribonucleoside catabolic process	8/1389	16/8135	2.93	2.49e-03	1.37e-02	16
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	8/1389	16/8135	2.93	2.49e-03	1.37e-02	16
GO:0051354	GO:0051354	negative regulation of oxidoreductase activity	8/1389	16/8135	2.93	2.49e-03	1.37e-02	16
GO:0030316	GO:0030316	osteoclast differentiation	20/1389	62/8135	1.89	2.50e-03	1.37e-02	62
GO:0002223	GO:0002223	stimulatory C-type lectin receptor signaling pathway	13/1389	34/8135	2.24	2.65e-03	1.44e-02	34
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	13/1389	34/8135	2.24	2.65e-03	1.44e-02	34
GO:1905517	GO:1905517	macrophage migration	13/1389	34/8135	2.24	2.65e-03	1.44e-02	34
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	18/1389	54/8135	1.95	2.70e-03	1.46e-02	54
GO:1900015	GO:1900015	regulation of cytokine production involved in inflammatory response	10/1389	23/8135	2.55	2.71e-03	1.47e-02	23
GO:0048535	GO:0048535	lymph node development	7/1389	13/8135	3.15	2.75e-03	1.47e-02	13
GO:0060330	GO:0060330	regulation of response to interferon-gamma	7/1389	13/8135	3.15	2.75e-03	1.47e-02	13
GO:0060334	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	7/1389	13/8135	3.15	2.75e-03	1.47e-02	13
GO:0090195	GO:0090195	chemokine secretion	7/1389	13/8135	3.15	2.75e-03	1.47e-02	13
GO:1901741	GO:1901741	positive regulation of myoblast fusion	7/1389	13/8135	3.15	2.75e-03	1.47e-02	13
GO:0002517	GO:0002517	T cell tolerance induction	6/1389	10/8135	3.51	2.76e-03	1.47e-02	10
GO:0030889	GO:0030889	negative regulation of B cell proliferation	6/1389	10/8135	3.51	2.76e-03	1.47e-02	10
GO:0032727	GO:0032727	positive regulation of interferon-alpha production	6/1389	10/8135	3.51	2.76e-03	1.47e-02	10
GO:0045623	GO:0045623	negative regulation of T-helper cell differentiation	6/1389	10/8135	3.51	2.76e-03	1.47e-02	10
GO:0045830	GO:0045830	positive regulation of isotype switching	6/1389	10/8135	3.51	2.76e-03	1.47e-02	10
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	14/1389	38/8135	2.16	2.76e-03	1.47e-02	38
GO:2000117	GO:2000117	negative regulation of cysteine-type endopeptidase activity	16/1389	46/8135	2.04	2.81e-03	1.49e-02	46
GO:0043154	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	15/1389	42/8135	2.09	2.81e-03	1.49e-02	42
GO:0072527	GO:0072527	pyrimidine-containing compound metabolic process	15/1389	42/8135	2.09	2.81e-03	1.49e-02	42
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	20/1389	63/8135	1.86	3.09e-03	1.64e-02	63
GO:0032642	GO:0032642	regulation of chemokine production	18/1389	55/8135	1.92	3.38e-03	1.79e-02	55
GO:0050764	GO:0050764	regulation of phagocytosis	17/1389	51/8135	1.95	3.50e-03	1.85e-02	51
GO:0008625	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	13/1389	35/8135	2.18	3.57e-03	1.88e-02	35
GO:0072577	GO:0072577	endothelial cell apoptotic process	13/1389	35/8135	2.18	3.57e-03	1.88e-02	35
GO:0032602	GO:0032602	chemokine production	19/1389	60/8135	1.85	4.00e-03	2.08e-02	60
GO:0061025	GO:0061025	membrane fusion	19/1389	60/8135	1.85	4.00e-03	2.08e-02	60
GO:0032608	GO:0032608	interferon-beta production	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0032648	GO:0032648	regulation of interferon-beta production	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0032703	GO:0032703	negative regulation of interleukin-2 production	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0034695	GO:0034695	response to prostaglandin E	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0035722	GO:0035722	interleukin-12-mediated signaling pathway	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0043124	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0043330	GO:0043330	response to exogenous dsRNA	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0070671	GO:0070671	response to interleukin-12	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:0071349	GO:0071349	cellular response to interleukin-12	8/1389	17/8135	2.76	4.01e-03	2.08e-02	17
GO:1901657	GO:1901657	glycosyl compound metabolic process	18/1389	56/8135	1.88	4.20e-03	2.17e-02	56
GO:1903707	GO:1903707	negative regulation of hemopoiesis	26/1389	91/8135	1.67	4.21e-03	2.17e-02	91
GO:0006958	GO:0006958	complement activation, classical pathway	11/1389	28/8135	2.30	4.37e-03	2.24e-02	28
GO:0032731	GO:0032731	positive regulation of interleukin-1 beta production	11/1389	28/8135	2.30	4.37e-03	2.24e-02	28
GO:1902041	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	11/1389	28/8135	2.30	4.37e-03	2.24e-02	28
GO:2001236	GO:2001236	regulation of extrinsic apoptotic signaling pathway	23/1389	78/8135	1.73	4.50e-03	2.31e-02	78
GO:0007229	GO:0007229	integrin-mediated signaling pathway	20/1389	65/8135	1.80	4.61e-03	2.36e-02	65
GO:2000351	GO:2000351	regulation of endothelial cell apoptotic process	12/1389	32/8135	2.20	4.62e-03	2.36e-02	32
GO:0030838	GO:0030838	positive regulation of actin filament polymerization	15/1389	44/8135	2.00	4.68e-03	2.38e-02	44
GO:0002922	GO:0002922	positive regulation of humoral immune response	7/1389	14/8135	2.93	4.69e-03	2.38e-02	14
GO:0045911	GO:0045911	positive regulation of DNA recombination	7/1389	14/8135	2.93	4.69e-03	2.38e-02	14
GO:0072643	GO:0072643	interferon-gamma secretion	7/1389	14/8135	2.93	4.69e-03	2.38e-02	14
GO:1903306	GO:1903306	negative regulation of regulated secretory pathway	7/1389	14/8135	2.93	4.69e-03	2.38e-02	14
GO:0009119	GO:0009119	ribonucleoside metabolic process	13/1389	36/8135	2.11	4.73e-03	2.39e-02	36
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	13/1389	36/8135	2.11	4.73e-03	2.39e-02	36
GO:0032677	GO:0032677	regulation of interleukin-8 production	14/1389	40/8135	2.05	4.74e-03	2.39e-02	40
GO:0048245	GO:0048245	eosinophil chemotaxis	9/1389	21/8135	2.51	4.96e-03	2.50e-02	21
GO:0002756	GO:0002756	MyD88-independent toll-like receptor signaling pathway	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0006216	GO:0006216	cytidine catabolic process	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0009972	GO:0009972	cytidine deamination	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0016554	GO:0016554	cytidine to uridine editing	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0032695	GO:0032695	negative regulation of interleukin-12 production	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0032823	GO:0032823	regulation of natural killer cell differentiation	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0033089	GO:0033089	positive regulation of T cell differentiation in thymus	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0034162	GO:0034162	toll-like receptor 9 signaling pathway	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0039528	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0042976	GO:0042976	activation of Janus kinase activity	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0046087	GO:0046087	cytidine metabolic process	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0051767	GO:0051767	nitric-oxide synthase biosynthetic process	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0051769	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0070230	GO:0070230	positive regulation of lymphocyte apoptotic process	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0071636	GO:0071636	positive regulation of transforming growth factor beta production	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0090197	GO:0090197	positive regulation of chemokine secretion	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:1904469	GO:1904469	positive regulation of tumor necrosis factor secretion	6/1389	11/8135	3.19	5.19e-03	2.55e-02	11
GO:0032637	GO:0032637	interleukin-8 production	15/1389	45/8135	1.95	5.93e-03	2.91e-02	45
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	11/1389	29/8135	2.22	5.97e-03	2.92e-02	29
GO:0035587	GO:0035587	purinergic receptor signaling pathway	11/1389	29/8135	2.22	5.97e-03	2.92e-02	29
GO:0019835	GO:0019835	cytolysis	12/1389	33/8135	2.13	6.15e-03	2.99e-02	33
GO:0002691	GO:0002691	regulation of cellular extravasation	8/1389	18/8135	2.60	6.16e-03	2.99e-02	18
GO:0009595	GO:0009595	detection of biotic stimulus	8/1389	18/8135	2.60	6.16e-03	2.99e-02	18
GO:0061028	GO:0061028	establishment of endothelial barrier	8/1389	18/8135	2.60	6.16e-03	2.99e-02	18
GO:0072376	GO:0072376	protein activation cascade	22/1389	76/8135	1.70	6.85e-03	3.33e-02	76
GO:0034142	GO:0034142	toll-like receptor 4 signaling pathway	9/1389	22/8135	2.40	7.14e-03	3.46e-02	22
GO:0010661	GO:0010661	positive regulation of muscle cell apoptotic process	7/1389	15/8135	2.73	7.51e-03	3.62e-02	15
GO:0032604	GO:0032604	granulocyte macrophage colony-stimulating factor production	7/1389	15/8135	2.73	7.51e-03	3.62e-02	15
GO:0043243	GO:0043243	positive regulation of protein complex disassembly	7/1389	15/8135	2.73	7.51e-03	3.62e-02	15
GO:1904037	GO:1904037	positive regulation of epithelial cell apoptotic process	7/1389	15/8135	2.73	7.51e-03	3.62e-02	15
GO:0045453	GO:0045453	bone resorption	14/1389	42/8135	1.95	7.73e-03	3.72e-02	42
GO:1904035	GO:1904035	regulation of epithelial cell apoptotic process	14/1389	42/8135	1.95	7.73e-03	3.72e-02	42
GO:0008037	GO:0008037	cell recognition	29/1389	109/8135	1.56	7.84e-03	3.76e-02	109
GO:0048017	GO:0048017	inositol lipid-mediated signaling	27/1389	100/8135	1.58	8.20e-03	3.93e-02	100
GO:0046488	GO:0046488	phosphatidylinositol metabolic process	31/1389	119/8135	1.53	8.46e-03	4.05e-02	119
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	23/1389	82/8135	1.64	8.71e-03	4.16e-02	82
GO:0032728	GO:0032728	positive regulation of interferon-beta production	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:0033004	GO:0033004	negative regulation of mast cell activation	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:0046133	GO:0046133	pyrimidine ribonucleoside catabolic process	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:0048143	GO:0048143	astrocyte activation	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:0090196	GO:0090196	regulation of chemokine secretion	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:2000353	GO:2000353	positive regulation of endothelial cell apoptotic process	6/1389	12/8135	2.93	8.89e-03	4.20e-02	12
GO:0002755	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	8/1389	19/8135	2.47	9.07e-03	4.25e-02	19
GO:0043331	GO:0043331	response to dsRNA	8/1389	19/8135	2.47	9.07e-03	4.25e-02	19
GO:0045920	GO:0045920	negative regulation of exocytosis	8/1389	19/8135	2.47	9.07e-03	4.25e-02	19
GO:2000482	GO:2000482	regulation of interleukin-8 secretion	8/1389	19/8135	2.47	9.07e-03	4.25e-02	19
GO:0001954	GO:0001954	positive regulation of cell-matrix adhesion	9/1389	23/8135	2.29	9.98e-03	4.65e-02	23
GO:0035588	GO:0035588	G protein-coupled purinergic receptor signaling pathway	9/1389	23/8135	2.29	9.98e-03	4.65e-02	23
GO:0042036	GO:0042036	negative regulation of cytokine biosynthetic process	9/1389	23/8135	2.29	9.98e-03	4.65e-02	23
GO:1905521	GO:1905521	regulation of macrophage migration	9/1389	23/8135	2.29	9.98e-03	4.65e-02	23
GO:0001960	GO:0001960	negative regulation of cytokine-mediated signaling pathway	12/1389	35/8135	2.01	1.04e-02	4.84e-02	35
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	10/1389	27/8135	2.17	1.04e-02	4.84e-02	27
GO:0050850	GO:0050850	positive regulation of calcium-mediated signaling	10/1389	27/8135	2.17	1.04e-02	4.84e-02	27
GO:0045124	GO:0045124	regulation of bone resorption	11/1389	31/8135	2.08	1.05e-02	4.88e-02	31

Summary:
Factor	1	2	3	4	5	6	7	8	9	10
Signif_GO_terms	0	14	4	197	913	1	0	2	77	0
Factor	11	12	13	14	15	16	17	18	19	20
Signif_GO_terms	10	3	281	736	28	3	495	1	188	756

3.1.1 Factors of interest

4: angiogenesis; all kinds of cell & tissue development/migration; regulation of Wnt signaling pathway
5: activation of immune response
9: microtubule-based movement; synaptic vesicle cycle
11: DNA repair; (cell cycle)
13: mitotic cell cycle
14: blood vessel development; regulation of cell migration; endothelial & epithelial cell proliferation
17: activation of immune response
19: blood vessel development; endothelium development
20: T cell activation; leukocyte cell-cell adhesion

3.2 GO enrichment per driver gene condition

Target: Genes w/ GSFA lfsr < 0.05 under each condition, stratefied by sign of effect;
Backgroud: all 10000 genes used in factor analysis.

GO terms that passed over-representation test fold change \(\geq\) 1.5 and q value \(<\) 0.05:

TP53_LOF_up : 143 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	171/2757	267/8135	1.89	1.51e-24	6.84e-21	267
GO:0000278	GO:0000278	mitotic cell cycle	197/2757	326/8135	1.78	1.48e-23	3.35e-20	326
GO:0022402	GO:0022402	cell cycle process	251/2757	470/8135	1.58	2.80e-19	4.24e-16	470
GO:0140014	GO:0140014	mitotic nuclear division	79/2757	107/8135	2.18	2.31e-17	2.61e-14	107
GO:0000070	GO:0000070	mitotic sister chromatid segregation	49/2757	56/8135	2.58	1.02e-16	9.20e-14	56
GO:0000819	GO:0000819	sister chromatid segregation	56/2757	68/8135	2.43	2.04e-16	1.54e-13	68
GO:0000280	GO:0000280	nuclear division	119/2757	192/8135	1.83	8.29e-16	5.36e-13	192
GO:0044772	GO:0044772	mitotic cell cycle phase transition	105/2757	164/8135	1.89	1.75e-15	9.90e-13	164
GO:0051276	GO:0051276	chromosome organization	204/2757	385/8135	1.56	2.46e-15	1.24e-12	385
GO:0044770	GO:0044770	cell cycle phase transition	110/2757	177/8135	1.83	7.99e-15	3.62e-12	177
GO:0007059	GO:0007059	chromosome segregation	81/2757	118/8135	2.03	9.24e-15	3.81e-12	118
GO:0048285	GO:0048285	organelle fission	122/2757	206/8135	1.75	4.54e-14	1.71e-11	206
GO:0098813	GO:0098813	nuclear chromosome segregation	72/2757	106/8135	2.00	6.57e-13	2.29e-10	106
GO:0006260	GO:0006260	DNA replication	56/2757	77/8135	2.15	3.13e-12	1.01e-09	77
GO:0071103	GO:0071103	DNA conformation change	78/2757	121/8135	1.90	4.63e-12	1.40e-09	121
GO:0007346	GO:0007346	regulation of mitotic cell cycle	117/2757	207/8135	1.67	1.20e-11	3.40e-09	207
GO:0051301	GO:0051301	cell division	121/2757	219/8135	1.63	4.14e-11	1.04e-08	219
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	38/2757	47/8135	2.39	4.53e-11	1.08e-08	47
GO:0010564	GO:0010564	regulation of cell cycle process	131/2757	243/8135	1.59	6.30e-11	1.43e-08	243
GO:0007052	GO:0007052	mitotic spindle organization	33/2757	39/8135	2.50	8.37e-11	1.81e-08	39
GO:0070268	GO:0070268	cornification	63/2757	95/8135	1.96	8.98e-11	1.85e-08	95
GO:0006259	GO:0006259	DNA metabolic process	154/2757	301/8135	1.51	2.49e-10	4.90e-08	301
GO:0007088	GO:0007088	regulation of mitotic nuclear division	53/2757	79/8135	1.98	1.50e-09	2.82e-07	79
GO:0007051	GO:0007051	spindle organization	38/2757	51/8135	2.20	3.26e-09	5.91e-07	51
GO:0006261	GO:0006261	DNA-dependent DNA replication	33/2757	42/8135	2.32	3.51e-09	6.11e-07	42
GO:0006281	GO:0006281	DNA repair	76/2757	130/8135	1.73	6.58e-09	1.10e-06	130
GO:0051783	GO:0051783	regulation of nuclear division	60/2757	96/8135	1.84	8.00e-09	1.29e-06	96
GO:0032392	GO:0032392	DNA geometric change	21/2757	23/8135	2.69	1.50e-08	2.32e-06	23
GO:0032508	GO:0032508	DNA duplex unwinding	19/2757	20/8135	2.80	1.54e-08	2.32e-06	20
GO:0051983	GO:0051983	regulation of chromosome segregation	28/2757	35/8135	2.36	2.74e-08	4.00e-06	35
GO:0051321	GO:0051321	meiotic cell cycle	80/2757	143/8135	1.65	4.10e-08	5.61e-06	143
GO:0031424	GO:0031424	keratinization	71/2757	123/8135	1.70	4.27e-08	5.61e-06	123
GO:0034502	GO:0034502	protein localization to chromosome	18/2757	19/8135	2.80	4.33e-08	5.61e-06	19
GO:0051310	GO:0051310	metaphase plate congression	18/2757	19/8135	2.80	4.33e-08	5.61e-06	19
GO:0044839	GO:0044839	cell cycle G2/M phase transition	48/2757	74/8135	1.91	4.60e-08	5.79e-06	74
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	66/2757	113/8135	1.72	6.83e-08	8.35e-06	113
GO:0006323	GO:0006323	DNA packaging	60/2757	100/8135	1.77	7.01e-08	8.35e-06	100
GO:1901987	GO:1901987	regulation of cell cycle phase transition	71/2757	125/8135	1.68	1.04e-07	1.21e-05	125
GO:0030216	GO:0030216	keratinocyte differentiation	87/2757	162/8135	1.58	1.34e-07	1.51e-05	162
GO:0045786	GO:0045786	negative regulation of cell cycle	108/2757	212/8135	1.50	1.66e-07	1.83e-05	212
GO:0065004	GO:0065004	protein-DNA complex assembly	58/2757	98/8135	1.75	2.26e-07	2.44e-05	98
GO:0007080	GO:0007080	mitotic metaphase plate congression	14/2757	14/8135	2.95	2.58e-07	2.72e-05	14
GO:0006302	GO:0006302	double-strand break repair	49/2757	79/8135	1.83	2.64e-07	2.72e-05	79
GO:1903046	GO:1903046	meiotic cell cycle process	64/2757	112/8135	1.69	3.28e-07	3.30e-05	112
GO:0000075	GO:0000075	cell cycle checkpoint	43/2757	67/8135	1.89	3.61e-07	3.56e-05	67
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	51/2757	84/8135	1.79	3.98e-07	3.83e-05	84
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	36/2757	53/8135	2.00	4.09e-07	3.86e-05	53
GO:0044843	GO:0044843	cell cycle G1/S phase transition	54/2757	91/8135	1.75	5.22e-07	4.82e-05	91
GO:0071824	GO:0071824	protein-DNA complex subunit organization	62/2757	109/8135	1.68	6.23e-07	5.64e-05	109
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	43/2757	68/8135	1.87	6.62e-07	5.78e-05	68
GO:0031497	GO:0031497	chromatin assembly	51/2757	85/8135	1.77	6.69e-07	5.78e-05	85
GO:0140013	GO:0140013	meiotic nuclear division	61/2757	107/8135	1.68	6.89e-07	5.78e-05	107
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	20/2757	24/8135	2.46	8.63e-07	6.86e-05	24
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	20/2757	24/8135	2.46	8.63e-07	6.86e-05	24
GO:0051306	GO:0051306	mitotic sister chromatid separation	20/2757	24/8135	2.46	8.63e-07	6.86e-05	24
GO:0006334	GO:0006334	nucleosome assembly	47/2757	77/8135	1.80	9.08e-07	7.10e-05	77
GO:0033045	GO:0033045	regulation of sister chromatid segregation	22/2757	28/8135	2.32	1.59e-06	1.22e-04	28
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	33/2757	49/8135	1.99	1.68e-06	1.27e-04	49
GO:0006333	GO:0006333	chromatin assembly or disassembly	52/2757	90/8135	1.70	2.62e-06	1.95e-04	90
GO:0051304	GO:0051304	chromosome separation	26/2757	36/8135	2.13	2.86e-06	2.09e-04	36
GO:1905818	GO:1905818	regulation of chromosome separation	20/2757	25/8135	2.36	2.94e-06	2.11e-04	25
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	34/2757	52/8135	1.93	3.27e-06	2.32e-04	52
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	30/2757	44/8135	2.01	3.39e-06	2.33e-04	44
GO:0000725	GO:0000725	recombinational repair	30/2757	44/8135	2.01	3.39e-06	2.33e-04	44
GO:0090307	GO:0090307	mitotic spindle assembly	17/2757	20/8135	2.51	3.59e-06	2.43e-04	20
GO:0051784	GO:0051784	negative regulation of nuclear division	22/2757	29/8135	2.24	4.48e-06	2.98e-04	29
GO:0034728	GO:0034728	nucleosome organization	50/2757	87/8135	1.70	5.02e-06	3.30e-04	87
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	52/2757	92/8135	1.67	6.38e-06	4.13e-04	92
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	31/2757	47/8135	1.95	6.78e-06	4.27e-04	47
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	40/2757	66/8135	1.79	7.53e-06	4.67e-04	66
GO:0010948	GO:0010948	negative regulation of cell cycle process	53/2757	95/8135	1.65	8.76e-06	5.36e-04	95
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/2757	19/8135	2.48	9.07e-06	5.41e-04	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/2757	19/8135	2.48	9.07e-06	5.41e-04	19
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	17/2757	21/8135	2.39	1.29e-05	7.47e-04	21
GO:0006342	GO:0006342	chromatin silencing	29/2757	44/8135	1.94	1.38e-05	7.89e-04	44
GO:0051052	GO:0051052	regulation of DNA metabolic process	68/2757	131/8135	1.53	1.43e-05	8.10e-04	131
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/2757	10/8135	2.95	1.98e-05	1.11e-03	10
GO:0006310	GO:0006310	DNA recombination	56/2757	104/8135	1.59	2.04e-05	1.12e-03	104
GO:0034508	GO:0034508	centromere complex assembly	20/2757	27/8135	2.19	2.27e-05	1.15e-03	27
GO:0050000	GO:0050000	chromosome localization	20/2757	27/8135	2.19	2.27e-05	1.15e-03	27
GO:0051303	GO:0051303	establishment of chromosome localization	20/2757	27/8135	2.19	2.27e-05	1.15e-03	27
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/2757	18/8135	2.46	2.28e-05	1.15e-03	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/2757	18/8135	2.46	2.28e-05	1.15e-03	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/2757	18/8135	2.46	2.28e-05	1.15e-03	18
GO:0090068	GO:0090068	positive regulation of cell cycle process	61/2757	116/8135	1.55	2.33e-05	1.16e-03	116
GO:0051225	GO:0051225	spindle assembly	21/2757	29/8135	2.14	2.50e-05	1.23e-03	29
GO:2001251	GO:2001251	negative regulation of chromosome organization	29/2757	45/8135	1.90	2.62e-05	1.27e-03	45
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	16/2757	20/8135	2.36	3.10e-05	1.48e-03	20
GO:0016458	GO:0016458	gene silencing	48/2757	87/8135	1.63	3.41e-05	1.61e-03	87
GO:0006270	GO:0006270	DNA replication initiation	13/2757	15/8135	2.56	3.78e-05	1.77e-03	15
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	17/2757	22/8135	2.28	3.86e-05	1.79e-03	22
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	18/2757	24/8135	2.21	4.51e-05	2.07e-03	24
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	11/2757	12/8135	2.70	5.54e-05	2.48e-03	12
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	11/2757	12/8135	2.70	5.54e-05	2.48e-03	12
GO:0007062	GO:0007062	sister chromatid cohesion	14/2757	17/8135	2.43	5.65e-05	2.51e-03	17
GO:0019730	GO:0019730	antimicrobial humoral response	47/2757	87/8135	1.59	8.30e-05	3.65e-03	87
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	53/2757	101/8135	1.55	8.46e-05	3.69e-03	101
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	16/2757	21/8135	2.25	8.92e-05	3.85e-03	21
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	12/2757	14/8135	2.53	9.75e-05	4.17e-03	14
GO:0030593	GO:0030593	neutrophil chemotaxis	48/2757	90/8135	1.57	1.07e-04	4.53e-03	90
GO:0031055	GO:0031055	chromatin remodeling at centromere	18/2757	25/8135	2.12	1.10e-04	4.62e-03	25
GO:0006275	GO:0006275	regulation of DNA replication	22/2757	33/8135	1.97	1.19e-04	4.94e-03	33
GO:0032200	GO:0032200	telomere organization	28/2757	46/8135	1.80	1.58e-04	6.50e-03	46
GO:0061982	GO:0061982	meiosis I cell cycle process	41/2757	75/8135	1.61	1.64e-04	6.67e-03	75
GO:0071621	GO:0071621	granulocyte chemotaxis	53/2757	103/8135	1.52	1.65e-04	6.67e-03	103
GO:1990266	GO:1990266	neutrophil migration	50/2757	96/8135	1.54	1.70e-04	6.81e-03	96
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	26/2757	42/8135	1.83	1.83e-04	7.20e-03	42
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	32/2757	55/8135	1.72	1.83e-04	7.20e-03	55
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	39/2757	71/8135	1.62	2.06e-04	8.05e-03	71
GO:0033044	GO:0033044	regulation of chromosome organization	50/2757	97/8135	1.52	2.37e-04	9.04e-03	97
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	17/2757	24/8135	2.09	2.37e-04	9.04e-03	24
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	17/2757	24/8135	2.09	2.37e-04	9.04e-03	24
GO:0000281	GO:0000281	mitotic cytokinesis	19/2757	28/8135	2.00	2.46e-04	9.30e-03	28
GO:0031570	GO:0031570	DNA integrity checkpoint	27/2757	45/8135	1.77	2.89e-04	1.08e-02	45
GO:0007127	GO:0007127	meiosis I	39/2757	72/8135	1.60	3.04e-04	1.13e-02	72
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:0031577	GO:0031577	spindle checkpoint	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	12/2757	15/8135	2.36	3.36e-04	1.19e-02	15
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	22/2757	35/8135	1.85	4.21e-04	1.47e-02	35
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	36/2757	66/8135	1.61	4.29e-04	1.48e-02	66
GO:0000910	GO:0000910	cytokinesis	31/2757	55/8135	1.66	4.98e-04	1.68e-02	55
GO:0043486	GO:0043486	histone exchange	18/2757	27/8135	1.97	5.02e-04	1.68e-02	27
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	16/2757	23/8135	2.05	5.04e-04	1.68e-02	23
GO:0045840	GO:0045840	positive regulation of mitotic nuclear division	16/2757	23/8135	2.05	5.04e-04	1.68e-02	23
GO:0061641	GO:0061641	CENP-A containing chromatin organization	16/2757	23/8135	2.05	5.04e-04	1.68e-02	23
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	21/2757	34/8135	1.82	7.96e-04	2.59e-02	34
GO:0044786	GO:0044786	cell cycle DNA replication	11/2757	14/8135	2.32	8.03e-04	2.60e-02	14
GO:0007098	GO:0007098	centrosome cycle	20/2757	32/8135	1.84	8.54e-04	2.74e-02	32
GO:0007143	GO:0007143	female meiotic nuclear division	12/2757	16/8135	2.21	9.29e-04	2.94e-02	16
GO:0006338	GO:0006338	chromatin remodeling	32/2757	59/8135	1.60	1.00e-03	3.15e-02	59
GO:1902751	GO:1902751	positive regulation of cell cycle G2/M phase transition	13/2757	18/8135	2.13	1.01e-03	3.15e-02	18
GO:0034660	GO:0034660	ncRNA metabolic process	34/2757	64/8135	1.57	1.15e-03	3.56e-02	64
GO:0006282	GO:0006282	regulation of DNA repair	22/2757	37/8135	1.75	1.24e-03	3.82e-02	37
GO:0045132	GO:0045132	meiotic chromosome segregation	29/2757	53/8135	1.61	1.42e-03	4.23e-02	53
GO:0060968	GO:0060968	regulation of gene silencing	29/2757	53/8135	1.61	1.42e-03	4.23e-02	53
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	32/2757	60/8135	1.57	1.46e-03	4.32e-02	60
GO:0000022	GO:0000022	mitotic spindle elongation	9/2757	11/8135	2.41	1.56e-03	4.50e-02	11
GO:0051231	GO:0051231	spindle elongation	9/2757	11/8135	2.41	1.56e-03	4.50e-02	11
GO:0090224	GO:0090224	regulation of spindle organization	9/2757	11/8135	2.41	1.56e-03	4.50e-02	11
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	18/2757	29/8135	1.83	1.74e-03	4.95e-02	29

TP53_LOF_down : 6 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0003341	GO:0003341	cilium movement	36/3093	46/8135	2.06	2.83e-08	0.000066	46
GO:0035082	GO:0035082	axoneme assembly	36/3093	46/8135	2.06	2.83e-08	0.000066	46
GO:0044782	GO:0044782	cilium organization	80/3093	132/8135	1.59	9.90e-08	0.000154	132
GO:0060271	GO:0060271	cilium assembly	74/3093	123/8135	1.58	4.50e-07	0.000525	123
GO:0070286	GO:0070286	axonemal dynein complex assembly	21/3093	25/8135	2.21	3.07e-06	0.002860	25
GO:0001578	GO:0001578	microtubule bundle formation	41/3093	62/8135	1.74	6.35e-06	0.004933	62

TP53_mis_up : 142 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	159/2722	267/8135	1.78	6.48e-19	2.59e-15	267
GO:0000278	GO:0000278	mitotic cell cycle	185/2722	326/8135	1.70	1.17e-18	2.59e-15	326
GO:0022402	GO:0022402	cell cycle process	239/2722	470/8135	1.52	8.75e-16	1.29e-12	470
GO:0051276	GO:0051276	chromosome organization	203/2722	385/8135	1.58	1.25e-15	1.38e-12	385
GO:0071103	GO:0071103	DNA conformation change	80/2722	121/8135	1.98	1.50e-13	1.14e-10	121
GO:0140014	GO:0140014	mitotic nuclear division	73/2722	107/8135	2.04	1.55e-13	1.14e-10	107
GO:0000819	GO:0000819	sister chromatid segregation	52/2722	68/8135	2.29	3.81e-13	2.41e-10	68
GO:0044772	GO:0044772	mitotic cell cycle phase transition	98/2722	164/8135	1.79	3.03e-12	1.68e-09	164
GO:0000070	GO:0000070	mitotic sister chromatid segregation	44/2722	56/8135	2.35	4.89e-12	2.40e-09	56
GO:0044770	GO:0044770	cell cycle phase transition	103/2722	177/8135	1.74	8.29e-12	3.67e-09	177
GO:0007059	GO:0007059	chromosome segregation	75/2722	118/8135	1.90	1.65e-11	6.44e-09	118
GO:0000280	GO:0000280	nuclear division	109/2722	192/8135	1.70	1.75e-11	6.44e-09	192
GO:0006260	GO:0006260	DNA replication	54/2722	77/8135	2.10	4.44e-11	1.51e-08	77
GO:0051301	GO:0051301	cell division	118/2722	219/8135	1.61	2.44e-10	7.72e-08	219
GO:0048285	GO:0048285	organelle fission	112/2722	206/8135	1.62	3.43e-10	1.01e-07	206
GO:0098813	GO:0098813	nuclear chromosome segregation	66/2722	106/8135	1.86	9.85e-10	2.73e-07	106
GO:0006323	GO:0006323	DNA packaging	63/2722	100/8135	1.88	1.19e-09	3.09e-07	100
GO:0070268	GO:0070268	cornification	60/2722	95/8135	1.89	2.56e-09	6.30e-07	95
GO:0019730	GO:0019730	antimicrobial humoral response	56/2722	87/8135	1.92	3.13e-09	7.29e-07	87
GO:0007346	GO:0007346	regulation of mitotic cell cycle	109/2722	207/8135	1.57	6.67e-09	1.48e-06	207
GO:0010564	GO:0010564	regulation of cell cycle process	124/2722	243/8135	1.53	7.51e-09	1.58e-06	243
GO:0030216	GO:0030216	keratinocyte differentiation	89/2722	162/8135	1.64	1.16e-08	2.23e-06	162
GO:0006261	GO:0006261	DNA-dependent DNA replication	32/2722	42/8135	2.28	1.64e-08	2.91e-06	42
GO:0051983	GO:0051983	regulation of chromosome segregation	28/2722	35/8135	2.39	2.00e-08	3.40e-06	35
GO:0031424	GO:0031424	keratinization	71/2722	123/8135	1.73	2.36e-08	3.88e-06	123
GO:0034502	GO:0034502	protein localization to chromosome	18/2722	19/8135	2.83	3.46e-08	5.47e-06	19
GO:0043588	GO:0043588	skin development	121/2722	241/8135	1.50	3.83e-08	5.84e-06	241
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	34/2722	47/8135	2.16	5.38e-08	7.94e-06	47
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	36/2722	52/8135	2.07	1.35e-07	1.88e-05	52
GO:0031497	GO:0031497	chromatin assembly	52/2722	85/8135	1.83	1.36e-07	1.88e-05	85
GO:0032392	GO:0032392	DNA geometric change	20/2722	23/8135	2.60	1.67e-07	2.21e-05	23
GO:0007088	GO:0007088	regulation of mitotic nuclear division	49/2722	79/8135	1.85	1.70e-07	2.21e-05	79
GO:0007052	GO:0007052	mitotic spindle organization	29/2722	39/8135	2.22	1.96e-07	2.42e-05	39
GO:0032508	GO:0032508	DNA duplex unwinding	18/2722	20/8135	2.69	2.37e-07	2.81e-05	20
GO:0000075	GO:0000075	cell cycle checkpoint	43/2722	67/8135	1.92	2.41e-07	2.81e-05	67
GO:0007051	GO:0007051	spindle organization	35/2722	51/8135	2.05	2.84e-07	3.22e-05	51
GO:0065004	GO:0065004	protein-DNA complex assembly	57/2722	98/8135	1.74	4.00e-07	4.42e-05	98
GO:0006333	GO:0006333	chromatin assembly or disassembly	53/2722	90/8135	1.76	5.91e-07	6.30e-05	90
GO:0006334	GO:0006334	nucleosome assembly	47/2722	77/8135	1.82	5.98e-07	6.30e-05	77
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	20/2722	24/8135	2.49	6.84e-07	6.73e-05	24
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	20/2722	24/8135	2.49	6.84e-07	6.73e-05	24
GO:0051306	GO:0051306	mitotic sister chromatid separation	20/2722	24/8135	2.49	6.84e-07	6.73e-05	24
GO:0010948	GO:0010948	negative regulation of cell cycle process	55/2722	95/8135	1.73	7.84e-07	7.38e-05	95
GO:0044843	GO:0044843	cell cycle G1/S phase transition	53/2722	91/8135	1.74	9.59e-07	8.85e-05	91
GO:0071824	GO:0071824	protein-DNA complex subunit organization	61/2722	109/8135	1.67	9.99e-07	9.03e-05	109
GO:0006281	GO:0006281	DNA repair	70/2722	130/8135	1.61	1.15e-06	1.01e-04	130
GO:0034728	GO:0034728	nucleosome organization	51/2722	87/8135	1.75	1.17e-06	1.01e-04	87
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	33/2722	49/8135	2.01	1.22e-06	1.02e-04	49
GO:0051783	GO:0051783	regulation of nuclear division	55/2722	96/8135	1.71	1.24e-06	1.02e-04	96
GO:0033045	GO:0033045	regulation of sister chromatid segregation	22/2722	28/8135	2.35	1.24e-06	1.02e-04	28
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	62/2722	113/8135	1.64	2.03e-06	1.63e-04	113
GO:0051304	GO:0051304	chromosome separation	26/2722	36/8135	2.16	2.18e-06	1.72e-04	36
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	49/2722	84/8135	1.74	2.30e-06	1.79e-04	84
GO:1905818	GO:1905818	regulation of chromosome separation	20/2722	25/8135	2.39	2.34e-06	1.79e-04	25
GO:1901987	GO:1901987	regulation of cell cycle phase transition	67/2722	125/8135	1.60	2.41e-06	1.81e-04	125
GO:0051784	GO:0051784	negative regulation of nuclear division	22/2722	29/8135	2.27	3.52e-06	2.60e-04	29
GO:0051321	GO:0051321	meiotic cell cycle	74/2722	143/8135	1.55	4.16e-06	2.97e-04	143
GO:0007062	GO:0007062	sister chromatid cohesion	15/2722	17/8135	2.64	4.63e-06	3.25e-04	17
GO:0006302	GO:0006302	double-strand break repair	46/2722	79/8135	1.74	5.01e-06	3.46e-04	79
GO:0007080	GO:0007080	mitotic metaphase plate congression	13/2722	14/8135	2.78	6.25e-06	4.26e-04	14
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/2722	19/8135	2.52	7.52e-06	4.83e-04	19
GO:0051310	GO:0051310	metaphase plate congression	16/2722	19/8135	2.52	7.52e-06	4.83e-04	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/2722	19/8135	2.52	7.52e-06	4.83e-04	19
GO:1903046	GO:1903046	meiotic cell cycle process	60/2722	112/8135	1.60	8.21e-06	5.19e-04	112
GO:0006342	GO:0006342	chromatin silencing	29/2722	44/8135	1.97	1.04e-05	6.48e-04	44
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	17/2722	21/8135	2.42	1.06e-05	6.51e-04	21
GO:0044839	GO:0044839	cell cycle G2/M phase transition	43/2722	74/8135	1.74	1.09e-05	6.56e-04	74
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	51/2722	92/8135	1.66	1.10e-05	6.56e-04	92
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	40/2722	68/8135	1.76	1.47e-05	8.34e-04	68
GO:0140013	GO:0140013	meiotic nuclear division	57/2722	107/8135	1.59	1.71e-05	9.48e-04	107
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/2722	10/8135	2.99	1.74e-05	9.51e-04	10
GO:0034508	GO:0034508	centromere complex assembly	20/2722	27/8135	2.21	1.83e-05	9.91e-04	27
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/2722	18/8135	2.49	1.91e-05	9.95e-04	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/2722	18/8135	2.49	1.91e-05	9.95e-04	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/2722	18/8135	2.49	1.91e-05	9.95e-04	18
GO:0016458	GO:0016458	gene silencing	48/2722	87/8135	1.65	2.34e-05	1.19e-03	87
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	16/2722	20/8135	2.39	2.59e-05	1.30e-03	20
GO:0006310	GO:0006310	DNA recombination	55/2722	104/8135	1.58	3.15e-05	1.57e-03	104
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	17/2722	22/8135	2.31	3.20e-05	1.57e-03	22
GO:0006270	GO:0006270	DNA replication initiation	13/2722	15/8135	2.59	3.24e-05	1.58e-03	15
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	18/2722	24/8135	2.24	3.71e-05	1.77e-03	24
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	28/2722	44/8135	1.90	3.90e-05	1.82e-03	44
GO:0000725	GO:0000725	recombinational repair	28/2722	44/8135	1.90	3.90e-05	1.82e-03	44
GO:0051052	GO:0051052	regulation of DNA metabolic process	66/2722	131/8135	1.51	4.12e-05	1.90e-03	131
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	11/2722	12/8135	2.74	4.84e-05	2.16e-03	12
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	11/2722	12/8135	2.74	4.84e-05	2.16e-03	12
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	32/2722	53/8135	1.80	5.12e-05	2.27e-03	53
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	29/2722	47/8135	1.84	6.54e-05	2.84e-03	47
GO:0031570	GO:0031570	DNA integrity checkpoint	28/2722	45/8135	1.86	7.04e-05	3.00e-03	45
GO:2001251	GO:2001251	negative regulation of chromosome organization	28/2722	45/8135	1.86	7.04e-05	3.00e-03	45
GO:0090068	GO:0090068	positive regulation of cell cycle process	59/2722	116/8135	1.52	7.33e-05	3.09e-03	116
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	16/2722	21/8135	2.28	7.48e-05	3.12e-03	21
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	12/2722	14/8135	2.56	8.46e-05	3.50e-03	14
GO:0031055	GO:0031055	chromatin remodeling at centromere	18/2722	25/8135	2.15	9.11e-05	3.74e-03	25
GO:0043486	GO:0043486	histone exchange	19/2722	27/8135	2.10	9.53e-05	3.78e-03	27
GO:0050000	GO:0050000	chromosome localization	19/2722	27/8135	2.10	9.53e-05	3.78e-03	27
GO:0051303	GO:0051303	establishment of chromosome localization	19/2722	27/8135	2.10	9.53e-05	3.78e-03	27
GO:0006275	GO:0006275	regulation of DNA replication	22/2722	33/8135	1.99	9.57e-05	3.78e-03	33
GO:0006338	GO:0006338	chromatin remodeling	34/2722	59/8135	1.72	1.13e-04	4.37e-03	59
GO:0071621	GO:0071621	granulocyte chemotaxis	53/2722	103/8135	1.54	1.14e-04	4.37e-03	103
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	37/2722	66/8135	1.68	1.27e-04	4.79e-03	66
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	37/2722	66/8135	1.68	1.27e-04	4.79e-03	66
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	32/2722	55/8135	1.74	1.39e-04	5.23e-03	55
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	39/2722	71/8135	1.64	1.52e-04	5.65e-03	71
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	17/2722	24/8135	2.12	1.99e-04	7.10e-03	24
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	17/2722	24/8135	2.12	1.99e-04	7.10e-03	24
GO:0000281	GO:0000281	mitotic cytokinesis	19/2722	28/8135	2.03	2.04e-04	7.21e-03	28
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	51/2722	101/8135	1.51	2.78e-04	9.46e-03	101
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:0031577	GO:0031577	spindle checkpoint	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	12/2722	15/8135	2.39	2.93e-04	9.48e-03	15
GO:0033044	GO:0033044	regulation of chromosome organization	49/2722	97/8135	1.51	3.59e-04	1.15e-02	97
GO:0032200	GO:0032200	telomere organization	27/2722	46/8135	1.75	3.77e-04	1.19e-02	46
GO:0030593	GO:0030593	neutrophil chemotaxis	46/2722	90/8135	1.53	3.83e-04	1.20e-02	90
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	19/2722	29/8135	1.96	4.06e-04	1.26e-02	29
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	16/2722	23/8135	2.08	4.28e-04	1.31e-02	23
GO:0061641	GO:0061641	CENP-A containing chromatin organization	16/2722	23/8135	2.08	4.28e-04	1.31e-02	23
GO:0060968	GO:0060968	regulation of gene silencing	30/2722	53/8135	1.69	4.33e-04	1.31e-02	53
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	33/2722	60/8135	1.64	4.66e-04	1.40e-02	60
GO:0070555	GO:0070555	response to interleukin-1	45/2722	89/8135	1.51	5.99e-04	1.73e-02	89
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	21/2722	34/8135	1.85	6.57e-04	1.88e-02	34
GO:0044786	GO:0044786	cell cycle DNA replication	11/2722	14/8135	2.35	7.10e-04	2.01e-02	14
GO:0090307	GO:0090307	mitotic spindle assembly	14/2722	20/8135	2.09	9.05e-04	2.52e-02	20
GO:0071347	GO:0071347	cellular response to interleukin-1	39/2722	76/8135	1.53	9.40e-04	2.60e-02	76
GO:0000910	GO:0000910	cytokinesis	30/2722	55/8135	1.63	1.00e-03	2.75e-02	55
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	21/2722	35/8135	1.79	1.13e-03	3.06e-02	35
GO:0018149	GO:0018149	peptide cross-linking	24/2722	42/8135	1.71	1.34e-03	3.58e-02	42
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	24/2722	42/8135	1.71	1.34e-03	3.58e-02	42
GO:0006586	GO:0006586	indolalkylamine metabolic process	9/2722	11/8135	2.45	1.41e-03	3.73e-02	11
GO:0007398	GO:0007398	ectoderm development	9/2722	11/8135	2.45	1.41e-03	3.73e-02	11
GO:0051225	GO:0051225	spindle assembly	18/2722	29/8135	1.86	1.47e-03	3.87e-02	29
GO:0061982	GO:0061982	meiosis I cell cycle process	38/2722	75/8135	1.51	1.48e-03	3.87e-02	75
GO:0045780	GO:0045780	positive regulation of bone resorption	10/2722	13/8135	2.30	1.69e-03	4.35e-02	13
GO:0046852	GO:0046852	positive regulation of bone remodeling	10/2722	13/8135	2.30	1.69e-03	4.35e-02	13
GO:0051782	GO:0051782	negative regulation of cell division	10/2722	13/8135	2.30	1.69e-03	4.35e-02	13
GO:0000183	GO:0000183	chromatin silencing at rDNA	16/2722	25/8135	1.91	1.70e-03	4.35e-02	25
GO:0034105	GO:0034105	positive regulation of tissue remodeling	14/2722	21/8135	1.99	1.88e-03	4.76e-02	21
GO:0002544	GO:0002544	chronic inflammatory response	12/2722	17/8135	2.11	1.93e-03	4.82e-02	17
GO:0006890	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	12/2722	17/8135	2.11	1.93e-03	4.82e-02	17

TP53_mis_down : 7 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0044782	GO:0044782	cilium organization	85/3053	132/8135	1.72	2.68e-10	9.59e-07	132
GO:0035082	GO:0035082	axoneme assembly	38/3053	46/8135	2.20	4.13e-10	9.59e-07	46
GO:0060271	GO:0060271	cilium assembly	79/3053	123/8135	1.71	1.38e-09	2.14e-06	123
GO:0003341	GO:0003341	cilium movement	36/3053	46/8135	2.09	1.91e-08	2.21e-05	46
GO:0001578	GO:0001578	microtubule bundle formation	44/3053	62/8135	1.89	8.49e-08	5.64e-05	62
GO:0070286	GO:0070286	axonemal dynein complex assembly	21/3053	25/8135	2.24	2.40e-06	1.39e-03	25
GO:0044458	GO:0044458	motile cilium assembly	11/3053	12/8135	2.44	1.62e-04	4.71e-02	12

CDH1_LOF_up : 7 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1901020	GO:1901020	negative regulation of calcium ion transmembrane transporter activity	17/3155	20/8135	2.19	2.90e-05	0.0161	20
GO:0030241	GO:0030241	skeletal muscle myosin thick filament assembly	11/3155	11/8135	2.58	2.95e-05	0.0161	11
GO:0031033	GO:0031033	myosin filament organization	11/3155	11/8135	2.58	2.95e-05	0.0161	11
GO:0031034	GO:0031034	myosin filament assembly	11/3155	11/8135	2.58	2.95e-05	0.0161	11
GO:0071688	GO:0071688	striated muscle myosin thick filament assembly	11/3155	11/8135	2.58	2.95e-05	0.0161	11
GO:1903170	GO:1903170	negative regulation of calcium ion transmembrane transport	18/3155	22/8135	2.11	4.54e-05	0.0213	22
GO:1901019	GO:1901019	regulation of calcium ion transmembrane transporter activity	36/3155	55/8135	1.69	5.37e-05	0.0213	55

CDH1_LOF_down : 263 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0051276	GO:0051276	chromosome organization	156/1142	385/8135	2.89	1.20e-39	4.93e-36	385
GO:1903047	GO:1903047	mitotic cell cycle process	114/1142	267/8135	3.04	2.09e-31	4.30e-28	267
GO:0000278	GO:0000278	mitotic cell cycle	128/1142	326/8135	2.80	7.82e-31	1.07e-27	326
GO:0071103	GO:0071103	DNA conformation change	71/1142	121/8135	4.18	1.17e-30	1.20e-27	121
GO:0007059	GO:0007059	chromosome segregation	69/1142	118/8135	4.17	1.08e-29	8.93e-27	118
GO:0022402	GO:0022402	cell cycle process	156/1142	470/8135	2.36	7.90e-28	5.43e-25	470
GO:0006323	GO:0006323	DNA packaging	59/1142	100/8135	4.20	7.98e-26	4.70e-23	100
GO:0000819	GO:0000819	sister chromatid segregation	47/1142	68/8135	4.92	3.47e-25	1.79e-22	68
GO:0098813	GO:0098813	nuclear chromosome segregation	60/1142	106/8135	4.03	6.58e-25	3.01e-22	106
GO:0006334	GO:0006334	nucleosome assembly	50/1142	77/8135	4.63	8.57e-25	3.54e-22	77
GO:0140014	GO:0140014	mitotic nuclear division	60/1142	107/8135	3.99	1.30e-24	4.87e-22	107
GO:0065004	GO:0065004	protein-DNA complex assembly	57/1142	98/8135	4.14	1.52e-24	5.23e-22	98
GO:0051301	GO:0051301	cell division	91/1142	219/8135	2.96	3.77e-24	1.20e-21	219
GO:0031497	GO:0031497	chromatin assembly	52/1142	85/8135	4.36	6.13e-24	1.81e-21	85
GO:0000070	GO:0000070	mitotic sister chromatid segregation	41/1142	56/8135	5.22	1.12e-23	3.09e-21	56
GO:0000280	GO:0000280	nuclear division	83/1142	192/8135	3.08	1.78e-23	4.58e-21	192
GO:0048285	GO:0048285	organelle fission	86/1142	206/8135	2.97	4.91e-23	1.19e-20	206
GO:0006333	GO:0006333	chromatin assembly or disassembly	52/1142	90/8135	4.12	2.63e-22	5.82e-20	90
GO:0034728	GO:0034728	nucleosome organization	51/1142	87/8135	4.18	2.69e-22	5.82e-20	87
GO:0071824	GO:0071824	protein-DNA complex subunit organization	58/1142	109/8135	3.79	2.82e-22	5.82e-20	109
GO:0006259	GO:0006259	DNA metabolic process	107/1142	301/8135	2.53	8.86e-22	1.74e-19	301
GO:0044770	GO:0044770	cell cycle phase transition	74/1142	177/8135	2.98	5.33e-20	9.99e-18	177
GO:0044772	GO:0044772	mitotic cell cycle phase transition	70/1142	164/8135	3.04	1.40e-19	2.51e-17	164
GO:0006302	GO:0006302	double-strand break repair	45/1142	79/8135	4.06	3.99e-19	6.81e-17	79
GO:0006325	GO:0006325	chromatin organization	93/1142	261/8135	2.54	4.13e-19	6.81e-17	261
GO:0006281	GO:0006281	DNA repair	60/1142	130/8135	3.29	5.65e-19	8.95e-17	130
GO:0006974	GO:0006974	cellular response to DNA damage stimulus	82/1142	230/8135	2.54	5.57e-17	8.50e-15	230
GO:0006260	GO:0006260	DNA replication	41/1142	77/8135	3.79	4.04e-16	5.95e-14	77
GO:0010564	GO:0010564	regulation of cell cycle process	82/1142	243/8135	2.40	2.22e-15	3.15e-13	243
GO:0006342	GO:0006342	chromatin silencing	29/1142	44/8135	4.70	3.73e-15	5.13e-13	44
GO:1901987	GO:1901987	regulation of cell cycle phase transition	53/1142	125/8135	3.02	5.75e-15	7.65e-13	125
GO:0051983	GO:0051983	regulation of chromosome segregation	25/1142	35/8135	5.09	1.70e-14	2.19e-12	35
GO:0000075	GO:0000075	cell cycle checkpoint	36/1142	67/8135	3.83	1.79e-14	2.23e-12	67
GO:0007346	GO:0007346	regulation of mitotic cell cycle	72/1142	207/8135	2.48	2.09e-14	2.53e-12	207
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	49/1142	113/8135	3.09	2.15e-14	2.53e-12	113
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	30/1142	49/8135	4.36	2.38e-14	2.72e-12	49
GO:0007088	GO:0007088	regulation of mitotic nuclear division	39/1142	79/8135	3.52	5.67e-14	6.32e-12	79
GO:0051726	GO:0051726	regulation of cell cycle	114/1142	412/8135	1.97	7.69e-14	8.35e-12	412
GO:0006261	GO:0006261	DNA-dependent DNA replication	27/1142	42/8135	4.58	8.50e-14	8.99e-12	42
GO:0007051	GO:0007051	spindle organization	30/1142	51/8135	4.19	1.09e-13	1.12e-11	51
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	28/1142	47/8135	4.24	4.67e-13	4.70e-11	47
GO:0051304	GO:0051304	chromosome separation	24/1142	36/8135	4.75	6.35e-13	6.24e-11	36
GO:0007052	GO:0007052	mitotic spindle organization	25/1142	39/8135	4.57	7.93e-13	7.61e-11	39
GO:0044839	GO:0044839	cell cycle G2/M phase transition	36/1142	74/8135	3.47	9.39e-13	8.80e-11	74
GO:0006310	GO:0006310	DNA recombination	44/1142	104/8135	3.01	1.33e-12	1.21e-10	104
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	30/1142	55/8135	3.89	1.66e-12	1.49e-10	55
GO:0034508	GO:0034508	centromere complex assembly	20/1142	27/8135	5.28	2.53e-12	2.22e-10	27
GO:0060968	GO:0060968	regulation of gene silencing	29/1142	53/8135	3.90	3.52e-12	2.93e-10	53
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	29/1142	53/8135	3.90	3.52e-12	2.93e-10	53
GO:0010948	GO:0010948	negative regulation of cell cycle process	41/1142	95/8135	3.07	3.56e-12	2.93e-10	95
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	18/1142	23/8135	5.57	6.65e-12	5.28e-10	23
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	18/1142	23/8135	5.57	6.65e-12	5.28e-10	23
GO:0033045	GO:0033045	regulation of sister chromatid segregation	20/1142	28/8135	5.09	7.69e-12	5.99e-10	28
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	33/1142	68/8135	3.46	9.17e-12	7.01e-10	68
GO:0032200	GO:0032200	telomere organization	26/1142	46/8135	4.03	1.73e-11	1.30e-09	46
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	32/1142	66/8135	3.45	1.96e-11	1.44e-09	66
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	18/1142	24/8135	5.34	2.31e-11	1.56e-09	24
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	18/1142	24/8135	5.34	2.31e-11	1.56e-09	24
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	18/1142	24/8135	5.34	2.31e-11	1.56e-09	24
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	18/1142	24/8135	5.34	2.31e-11	1.56e-09	24
GO:0051306	GO:0051306	mitotic sister chromatid separation	18/1142	24/8135	5.34	2.31e-11	1.56e-09	24
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	26/1142	47/8135	3.94	3.36e-11	2.24e-09	47
GO:0051321	GO:0051321	meiotic cell cycle	51/1142	143/8135	2.54	5.03e-11	3.30e-09	143
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	16/1142	20/8135	5.70	5.75e-11	3.71e-09	20
GO:0031570	GO:0031570	DNA integrity checkpoint	25/1142	45/8135	3.96	7.12e-11	4.35e-09	45
GO:0000183	GO:0000183	chromatin silencing at rDNA	18/1142	25/8135	5.13	7.18e-11	4.35e-09	25
GO:0031055	GO:0031055	chromatin remodeling at centromere	18/1142	25/8135	5.13	7.18e-11	4.35e-09	25
GO:1905818	GO:1905818	regulation of chromosome separation	18/1142	25/8135	5.13	7.18e-11	4.35e-09	25
GO:0000910	GO:0000910	cytokinesis	28/1142	55/8135	3.63	8.23e-11	4.92e-09	55
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	38/1142	92/8135	2.94	1.08e-10	6.38e-09	92
GO:1903046	GO:1903046	meiotic cell cycle process	43/1142	112/8135	2.73	1.11e-10	6.42e-09	112
GO:0051783	GO:0051783	regulation of nuclear division	39/1142	96/8135	2.89	1.12e-10	6.42e-09	96
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	17/1142	23/8135	5.27	1.25e-10	6.99e-09	23
GO:0061641	GO:0061641	CENP-A containing chromatin organization	17/1142	23/8135	5.27	1.25e-10	6.99e-09	23
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	29/1142	60/8135	3.44	1.91e-10	1.05e-08	60
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	16/1142	21/8135	5.43	2.10e-10	1.13e-08	21
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	16/1142	21/8135	5.43	2.10e-10	1.13e-08	21
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	19/1142	29/8135	4.67	2.71e-10	1.43e-08	29
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	24/1142	44/8135	3.89	2.88e-10	1.48e-08	44
GO:0000725	GO:0000725	recombinational repair	24/1142	44/8135	3.89	2.88e-10	1.48e-08	44
GO:0034502	GO:0034502	protein localization to chromosome	15/1142	19/8135	5.62	3.32e-10	1.67e-08	19
GO:0051310	GO:0051310	metaphase plate congression	15/1142	19/8135	5.62	3.32e-10	1.67e-08	19
GO:0043486	GO:0043486	histone exchange	18/1142	27/8135	4.75	5.29e-10	2.63e-08	27
GO:2001251	GO:2001251	negative regulation of chromosome organization	24/1142	45/8135	3.80	5.36e-10	2.63e-08	45
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	16/1142	22/8135	5.18	6.70e-10	3.23e-08	22
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	39/1142	101/8135	2.75	6.73e-10	3.23e-08	101
GO:0140013	GO:0140013	meiotic nuclear division	40/1142	107/8135	2.66	1.26e-09	5.98e-08	107
GO:0016458	GO:0016458	gene silencing	35/1142	87/8135	2.87	1.39e-09	6.50e-08	87
GO:0044843	GO:0044843	cell cycle G1/S phase transition	36/1142	91/8135	2.82	1.40e-09	6.50e-08	91
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	20/1142	34/8135	4.19	1.48e-09	6.78e-08	34
GO:0090068	GO:0090068	positive regulation of cell cycle process	42/1142	116/8135	2.58	1.53e-09	6.92e-08	116
GO:0045786	GO:0045786	negative regulation of cell cycle	63/1142	212/8135	2.12	1.75e-09	7.84e-08	212
GO:0006303	GO:0006303	double-strand break repair via nonhomologous end joining	16/1142	23/8135	4.96	1.92e-09	8.50e-08	23
GO:0045787	GO:0045787	positive regulation of cell cycle	53/1142	166/8135	2.27	2.19e-09	9.59e-08	166
GO:0033044	GO:0033044	regulation of chromosome organization	37/1142	97/8135	2.72	2.76e-09	1.19e-07	97
GO:0060964	GO:0060964	regulation of gene silencing by miRNA	21/1142	38/8135	3.94	2.76e-09	1.19e-07	38
GO:1902750	GO:1902750	negative regulation of cell cycle G2/M phase transition	15/1142	21/8135	5.09	3.52e-09	1.50e-07	21
GO:0050000	GO:0050000	chromosome localization	17/1142	27/8135	4.49	5.99e-09	2.50e-07	27
GO:0051303	GO:0051303	establishment of chromosome localization	17/1142	27/8135	4.49	5.99e-09	2.50e-07	27
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	14/1142	19/8135	5.25	6.26e-09	2.56e-07	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	14/1142	19/8135	5.25	6.26e-09	2.56e-07	19
GO:0060147	GO:0060147	regulation of posttranscriptional gene silencing	21/1142	40/8135	3.74	9.51e-09	3.81e-07	40
GO:0060966	GO:0060966	regulation of gene silencing by RNA	21/1142	40/8135	3.74	9.51e-09	3.81e-07	40
GO:0000726	GO:0000726	non-recombinational repair	16/1142	25/8135	4.56	1.21e-08	4.79e-07	25
GO:0000281	GO:0000281	mitotic cytokinesis	17/1142	28/8135	4.32	1.33e-08	5.21e-07	28
GO:0006270	GO:0006270	DNA replication initiation	12/1142	15/8135	5.70	1.68e-08	6.53e-07	15
GO:0090307	GO:0090307	mitotic spindle assembly	14/1142	20/8135	4.99	1.82e-08	7.01e-07	20
GO:0006338	GO:0006338	chromatin remodeling	26/1142	59/8135	3.14	1.94e-08	7.40e-07	59
GO:0061982	GO:0061982	meiosis I cell cycle process	30/1142	75/8135	2.85	2.45e-08	9.27e-07	75
GO:0051225	GO:0051225	spindle assembly	17/1142	29/8135	4.18	2.79e-08	1.05e-06	29
GO:0051052	GO:0051052	regulation of DNA metabolic process	43/1142	131/8135	2.34	2.92e-08	1.09e-06	131
GO:0030261	GO:0030261	chromosome condensation	13/1142	18/8135	5.14	3.33e-08	1.19e-06	18
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	13/1142	18/8135	5.14	3.33e-08	1.19e-06	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	13/1142	18/8135	5.14	3.33e-08	1.19e-06	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	13/1142	18/8135	5.14	3.33e-08	1.19e-06	18
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	32/1142	84/8135	2.71	3.38e-08	1.20e-06	84
GO:0045132	GO:0045132	meiotic chromosome segregation	24/1142	53/8135	3.23	3.57e-08	1.26e-06	53
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	15/1142	24/8135	4.45	5.60e-08	1.96e-06	24
GO:0007080	GO:0007080	mitotic metaphase plate congression	11/1142	14/8135	5.60	9.68e-08	3.33e-06	14
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	11/1142	14/8135	5.60	9.68e-08	3.33e-06	14
GO:0000018	GO:0000018	regulation of DNA recombination	20/1142	41/8135	3.47	1.07e-07	3.65e-06	41
GO:0000077	GO:0000077	DNA damage checkpoint	19/1142	38/8135	3.56	1.35e-07	4.57e-06	38
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	10/1142	12/8135	5.94	1.45e-07	4.85e-06	12
GO:0007127	GO:0007127	meiosis I	28/1142	72/8135	2.77	1.46e-07	4.85e-06	72
GO:0035195	GO:0035195	gene silencing by miRNA	22/1142	49/8135	3.20	1.60e-07	5.29e-06	49
GO:0007062	GO:0007062	sister chromatid cohesion	12/1142	17/8135	5.03	1.74e-07	5.64e-06	17
GO:0010972	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	12/1142	17/8135	5.03	1.74e-07	5.64e-06	17
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	9/1142	10/8135	6.41	1.80e-07	5.81e-06	10
GO:0007098	GO:0007098	centrosome cycle	17/1142	32/8135	3.78	2.00e-07	6.34e-06	32
GO:0051290	GO:0051290	protein heterotetramerization	17/1142	32/8135	3.78	2.00e-07	6.34e-06	32
GO:0045652	GO:0045652	regulation of megakaryocyte differentiation	19/1142	39/8135	3.47	2.29e-07	7.19e-06	39
GO:0051784	GO:0051784	negative regulation of nuclear division	16/1142	29/8135	3.93	2.30e-07	7.19e-06	29
GO:0032392	GO:0032392	DNA geometric change	14/1142	23/8135	4.34	2.53e-07	7.85e-06	23
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:0031577	GO:0031577	spindle checkpoint	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:0071173	GO:0071173	spindle assembly checkpoint	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	11/1142	15/8135	5.22	3.17e-07	9.40e-06	15
GO:0044774	GO:0044774	mitotic DNA integrity checkpoint	17/1142	33/8135	3.67	3.59e-07	1.06e-05	33
GO:0032465	GO:0032465	regulation of cytokinesis	16/1142	31/8135	3.68	7.71e-07	2.26e-05	31
GO:0016441	GO:0016441	posttranscriptional gene silencing	22/1142	53/8135	2.96	8.50e-07	2.45e-05	53
GO:0035194	GO:0035194	posttranscriptional gene silencing by RNA	22/1142	53/8135	2.96	8.50e-07	2.45e-05	53
GO:0030219	GO:0030219	megakaryocyte differentiation	20/1142	47/8135	3.03	1.67e-06	4.80e-05	47
GO:0000723	GO:0000723	telomere maintenance	17/1142	36/8135	3.36	1.74e-06	4.95e-05	36
GO:0045910	GO:0045910	negative regulation of DNA recombination	11/1142	17/8135	4.61	2.19e-06	6.18e-05	17
GO:2000779	GO:2000779	regulation of double-strand break repair	13/1142	23/8135	4.03	2.24e-06	6.28e-05	23
GO:0032508	GO:0032508	DNA duplex unwinding	12/1142	20/8135	4.27	2.35e-06	6.54e-05	20
GO:0031047	GO:0031047	gene silencing by RNA	24/1142	64/8135	2.67	2.43e-06	6.74e-05	64
GO:0006282	GO:0006282	regulation of DNA repair	17/1142	37/8135	3.27	2.80e-06	7.65e-05	37
GO:0031023	GO:0031023	microtubule organizing center organization	17/1142	37/8135	3.27	2.80e-06	7.65e-05	37
GO:0031572	GO:0031572	G2 DNA damage checkpoint	9/1142	12/8135	5.34	3.03e-06	8.18e-05	12
GO:0044818	GO:0044818	mitotic G2/M transition checkpoint	9/1142	12/8135	5.34	3.03e-06	8.18e-05	12
GO:0046605	GO:0046605	regulation of centrosome cycle	10/1142	15/8135	4.75	4.39e-06	1.18e-04	15
GO:0000079	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	18/1142	42/8135	3.05	4.90e-06	1.30e-04	42
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	18/1142	42/8135	3.05	4.90e-06	1.30e-04	42
GO:0000226	GO:0000226	microtubule cytoskeleton organization	56/1142	224/8135	1.78	7.01e-06	1.84e-04	224
GO:0072401	GO:0072401	signal transduction involved in DNA integrity checkpoint	12/1142	22/8135	3.89	9.17e-06	2.38e-04	22
GO:0072422	GO:0072422	signal transduction involved in DNA damage checkpoint	12/1142	22/8135	3.89	9.17e-06	2.38e-04	22
GO:1904029	GO:1904029	regulation of cyclin-dependent protein kinase activity	18/1142	45/8135	2.85	1.57e-05	4.04e-04	45
GO:0036297	GO:0036297	interstrand cross-link repair	8/1142	11/8135	5.18	1.64e-05	4.12e-04	11
GO:0045738	GO:0045738	negative regulation of DNA repair	8/1142	11/8135	5.18	1.64e-05	4.12e-04	11
GO:0070316	GO:0070316	regulation of G0 to G1 transition	8/1142	11/8135	5.18	1.64e-05	4.12e-04	11
GO:2000780	GO:2000780	negative regulation of double-strand break repair	8/1142	11/8135	5.18	1.64e-05	4.12e-04	11
GO:0072395	GO:0072395	signal transduction involved in cell cycle checkpoint	12/1142	23/8135	3.72	1.67e-05	4.18e-04	23
GO:0051607	GO:0051607	defense response to virus	34/1142	118/8135	2.05	2.05e-05	5.10e-04	118
GO:0044786	GO:0044786	cell cycle DNA replication	9/1142	14/8135	4.58	2.11e-05	5.22e-04	14
GO:0010569	GO:0010569	regulation of double-strand break repair via homologous recombination	10/1142	17/8135	4.19	2.17e-05	5.33e-04	17
GO:0034622	GO:0034622	cellular protein-containing complex assembly	81/1142	372/8135	1.55	2.22e-05	5.41e-04	372
GO:0098542	GO:0098542	defense response to other organism	62/1142	268/8135	1.65	3.17e-05	7.68e-04	268
GO:0051053	GO:0051053	negative regulation of DNA metabolic process	17/1142	43/8135	2.82	3.23e-05	7.78e-04	43
GO:0009314	GO:0009314	response to radiation	47/1142	188/8135	1.78	3.79e-05	9.09e-04	188
GO:0007017	GO:0007017	microtubule-based process	67/1142	298/8135	1.60	4.02e-05	9.59e-04	298
GO:0016233	GO:0016233	telomere capping	10/1142	18/8135	3.96	4.27e-05	1.01e-03	18
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	8/1142	12/8135	4.75	4.31e-05	1.01e-03	12
GO:0045023	GO:0045023	G0 to G1 transition	8/1142	12/8135	4.75	4.31e-05	1.01e-03	12
GO:0051640	GO:0051640	organelle localization	59/1142	254/8135	1.65	4.33e-05	1.01e-03	254
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	22/1142	66/8135	2.37	5.41e-05	1.25e-03	66
GO:0044773	GO:0044773	mitotic DNA damage checkpoint	13/1142	29/8135	3.19	5.84e-05	1.34e-03	29
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	15/1142	37/8135	2.89	6.65e-05	1.52e-03	37
GO:0007143	GO:0007143	female meiotic nuclear division	9/1142	16/8135	4.01	9.26e-05	2.11e-03	16
GO:0045143	GO:0045143	homologous chromosome segregation	15/1142	38/8135	2.81	9.58e-05	2.17e-03	38
GO:0031935	GO:0031935	regulation of chromatin silencing	8/1142	13/8135	4.38	9.83e-05	2.18e-03	13
GO:0045653	GO:0045653	negative regulation of megakaryocyte differentiation	8/1142	13/8135	4.38	9.83e-05	2.18e-03	13
GO:0051438	GO:0051438	regulation of ubiquitin-protein transferase activity	8/1142	13/8135	4.38	9.83e-05	2.18e-03	13
GO:0051782	GO:0051782	negative regulation of cell division	8/1142	13/8135	4.38	9.83e-05	2.18e-03	13
GO:0042770	GO:0042770	signal transduction in response to DNA damage	16/1142	43/8135	2.65	1.29e-04	2.84e-03	43
GO:0010608	GO:0010608	posttranscriptional regulation of gene expression	37/1142	144/8135	1.83	1.36e-04	2.96e-03	144
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	14/1142	35/8135	2.85	1.38e-04	3.00e-03	35
GO:0006063	GO:0006063	uronic acid metabolic process	9/1142	17/8135	3.77	1.72e-04	3.68e-03	17
GO:0006890	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	9/1142	17/8135	3.77	1.72e-04	3.68e-03	17
GO:0019585	GO:0019585	glucuronate metabolic process	9/1142	17/8135	3.77	1.72e-04	3.68e-03	17
GO:0007131	GO:0007131	reciprocal meiotic recombination	12/1142	28/8135	3.05	1.91e-04	4.04e-03	28
GO:0035825	GO:0035825	homologous recombination	12/1142	28/8135	3.05	1.91e-04	4.04e-03	28
GO:0051307	GO:0051307	meiotic chromosome separation	8/1142	14/8135	4.07	2.01e-04	4.23e-03	14
GO:0051262	GO:0051262	protein tetramerization	24/1142	81/8135	2.11	2.06e-04	4.31e-03	81
GO:0009812	GO:0009812	flavonoid metabolic process	7/1142	11/8135	4.53	2.08e-04	4.32e-03	11
GO:0070647	GO:0070647	protein modification by small protein conjugation or removal	56/1142	251/8135	1.59	2.11e-04	4.38e-03	251
GO:0010212	GO:0010212	response to ionizing radiation	16/1142	45/8135	2.53	2.40e-04	4.92e-03	45
GO:0016567	GO:0016567	protein ubiquitination	46/1142	197/8135	1.66	2.59e-04	5.29e-03	197
GO:0051302	GO:0051302	regulation of cell division	25/1142	87/8135	2.05	2.60e-04	5.29e-03	87
GO:0007140	GO:0007140	male meiotic nuclear division	13/1142	33/8135	2.81	2.86e-04	5.78e-03	33
GO:0031123	GO:0031123	RNA 3’-end processing	9/1142	18/8135	3.56	3.02e-04	6.07e-03	18
GO:2001020	GO:2001020	regulation of response to DNA damage stimulus	21/1142	69/8135	2.17	3.37e-04	6.75e-03	69
GO:0045815	GO:0045815	positive regulation of gene expression, epigenetic	8/1142	15/8135	3.80	3.78e-04	7.49e-03	15
GO:0052695	GO:0052695	cellular glucuronidation	8/1142	15/8135	3.80	3.78e-04	7.49e-03	15
GO:0051656	GO:0051656	establishment of organelle localization	47/1142	206/8135	1.63	3.92e-04	7.74e-03	206
GO:0070507	GO:0070507	regulation of microtubule cytoskeleton organization	20/1142	65/8135	2.19	3.95e-04	7.76e-03	65
GO:0002385	GO:0002385	mucosal immune response	11/1142	26/8135	3.01	4.05e-04	7.88e-03	26
GO:0031936	GO:0031936	negative regulation of chromatin silencing	7/1142	12/8135	4.16	4.38e-04	8.44e-03	12
GO:0033260	GO:0033260	nuclear DNA replication	7/1142	12/8135	4.16	4.38e-04	8.44e-03	12
GO:0032446	GO:0032446	protein modification by small protein conjugation	47/1142	207/8135	1.62	4.41e-04	8.45e-03	207
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	21/1142	71/8135	2.11	5.18e-04	9.88e-03	71
GO:0038111	GO:0038111	interleukin-7-mediated signaling pathway	10/1142	23/8135	3.10	5.73e-04	1.09e-02	23
GO:0071158	GO:0071158	positive regulation of cell cycle arrest	11/1142	27/8135	2.90	5.98e-04	1.13e-02	27
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	15/1142	44/8135	2.43	6.25e-04	1.18e-02	44
GO:0002227	GO:0002227	innate immune response in mucosa	8/1142	16/8135	3.56	6.63e-04	1.24e-02	16
GO:0022412	GO:0022412	cellular process involved in reproduction in multicellular organism	44/1142	195/8135	1.61	7.61e-04	1.41e-02	195
GO:1902806	GO:1902806	regulation of cell cycle G1/S phase transition	17/1142	54/8135	2.24	7.91e-04	1.46e-02	54
GO:0016073	GO:0016073	snRNA metabolic process	7/1142	13/8135	3.84	8.34e-04	1.53e-02	13
GO:0051298	GO:0051298	centrosome duplication	7/1142	13/8135	3.84	8.34e-04	1.53e-02	13
GO:0098760	GO:0098760	response to interleukin-7	10/1142	24/8135	2.97	8.60e-04	1.56e-02	24
GO:0098761	GO:0098761	cellular response to interleukin-7	10/1142	24/8135	2.97	8.60e-04	1.56e-02	24
GO:0002251	GO:0002251	organ or tissue specific immune response	11/1142	28/8135	2.80	8.61e-04	1.56e-02	28
GO:0000729	GO:0000729	DNA double-strand break processing	6/1142	10/8135	4.27	9.56e-04	1.70e-02	10
GO:0006998	GO:0006998	nuclear envelope organization	6/1142	10/8135	4.27	9.56e-04	1.70e-02	10
GO:0035458	GO:0035458	cellular response to interferon-beta	6/1142	10/8135	4.27	9.56e-04	1.70e-02	10
GO:0045005	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	6/1142	10/8135	4.27	9.56e-04	1.70e-02	10
GO:0006977	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:0072413	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:0072431	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:1902400	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:1902402	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:1902403	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	8/1142	17/8135	3.35	1.10e-03	1.91e-02	17
GO:0006275	GO:0006275	regulation of DNA replication	12/1142	33/8135	2.59	1.13e-03	1.96e-02	33
GO:0018149	GO:0018149	peptide cross-linking	14/1142	42/8135	2.37	1.21e-03	2.08e-02	42
GO:0043900	GO:0043900	regulation of multi-organism process	42/1142	188/8135	1.59	1.22e-03	2.09e-02	188
GO:0044380	GO:0044380	protein localization to cytoskeleton	7/1142	14/8135	3.56	1.47e-03	2.50e-02	14
GO:0009615	GO:0009615	response to virus	37/1142	162/8135	1.63	1.54e-03	2.61e-02	162
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	14/1142	43/8135	2.32	1.57e-03	2.65e-02	43
GO:0051291	GO:0051291	protein heterooligomerization	20/1142	72/8135	1.98	1.65e-03	2.78e-02	72
GO:0016572	GO:0016572	histone phosphorylation	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:0031571	GO:0031571	mitotic G1 DNA damage checkpoint	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:0032467	GO:0032467	positive regulation of cytokinesis	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:0044783	GO:0044783	G1 DNA damage checkpoint	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:0044819	GO:0044819	mitotic G1/S transition checkpoint	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:1902751	GO:1902751	positive regulation of cell cycle G2/M phase transition	8/1142	18/8135	3.17	1.74e-03	2.85e-02	18
GO:2001021	GO:2001021	negative regulation of response to DNA damage stimulus	10/1142	26/8135	2.74	1.79e-03	2.91e-02	26
GO:0016445	GO:0016445	somatic diversification of immunoglobulins	9/1142	22/8135	2.91	1.82e-03	2.95e-02	22
GO:0000022	GO:0000022	mitotic spindle elongation	6/1142	11/8135	3.89	1.85e-03	2.98e-02	11
GO:0051231	GO:0051231	spindle elongation	6/1142	11/8135	3.89	1.85e-03	2.98e-02	11
GO:0016569	GO:0016569	covalent chromatin modification	29/1142	120/8135	1.72	1.95e-03	3.12e-02	120
GO:0016032	GO:0016032	viral process	45/1142	211/8135	1.52	2.25e-03	3.58e-02	211
GO:0010639	GO:0010639	negative regulation of organelle organization	33/1142	143/8135	1.64	2.25e-03	3.58e-02	143
GO:0007129	GO:0007129	synapsis	11/1142	31/8135	2.53	2.27e-03	3.58e-02	31
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	16/1142	54/8135	2.11	2.28e-03	3.58e-02	54
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	13/1142	40/8135	2.32	2.33e-03	3.65e-02	40
GO:0030148	GO:0030148	sphingolipid biosynthetic process	17/1142	59/8135	2.05	2.34e-03	3.66e-02	59
GO:0070268	GO:0070268	cornification	24/1142	95/8135	1.80	2.48e-03	3.86e-02	95
GO:0045840	GO:0045840	positive regulation of mitotic nuclear division	9/1142	23/8135	2.79	2.63e-03	4.07e-02	23
GO:0030330	GO:0030330	DNA damage response, signal transduction by p53 class mediator	12/1142	36/8135	2.37	2.67e-03	4.13e-02	36
GO:0071156	GO:0071156	regulation of cell cycle arrest	13/1142	41/8135	2.26	2.98e-03	4.56e-02	41
GO:0072698	GO:0072698	protein localization to microtubule cytoskeleton	6/1142	12/8135	3.56	3.27e-03	4.98e-02	12

GATA3_LOF_up : 87 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0044782	GO:0044782	cilium organization	59/743	132/8135	4.89	1.70e-27	6.42e-24	132
GO:0060271	GO:0060271	cilium assembly	55/743	123/8135	4.90	1.05e-25	1.99e-22	123
GO:0001578	GO:0001578	microtubule bundle formation	36/743	62/8135	6.36	3.64e-22	3.44e-19	62
GO:0003341	GO:0003341	cilium movement	31/743	46/8135	7.38	4.55e-22	3.44e-19	46
GO:0035082	GO:0035082	axoneme assembly	31/743	46/8135	7.38	4.55e-22	3.44e-19	46
GO:0007017	GO:0007017	microtubule-based process	78/743	298/8135	2.87	1.48e-18	9.30e-16	298
GO:0120031	GO:0120031	plasma membrane bounded cell projection assembly	63/743	222/8135	3.11	5.09e-17	2.74e-14	222
GO:0030031	GO:0030031	cell projection assembly	64/743	231/8135	3.03	1.06e-16	4.98e-14	231
GO:0007018	GO:0007018	microtubule-based movement	39/743	119/8135	3.59	3.63e-13	1.52e-10	119
GO:0070286	GO:0070286	axonemal dynein complex assembly	17/743	25/8135	7.45	9.67e-13	3.65e-10	25
GO:0070925	GO:0070925	organelle assembly	64/743	279/8135	2.51	1.67e-12	5.72e-10	279
GO:0000226	GO:0000226	microtubule cytoskeleton organization	55/743	224/8135	2.69	3.80e-12	1.19e-09	224
GO:0044458	GO:0044458	motile cilium assembly	11/743	12/8135	10.00	3.80e-11	1.10e-08	12
GO:0034622	GO:0034622	cellular protein-containing complex assembly	71/743	372/8135	2.09	8.44e-10	2.28e-07	372
GO:0003351	GO:0003351	epithelial cilium movement	12/743	17/8135	7.73	1.25e-09	3.14e-07	17
GO:0006334	GO:0006334	nucleosome assembly	26/743	77/8135	3.70	1.58e-09	3.72e-07	77
GO:0031497	GO:0031497	chromatin assembly	26/743	85/8135	3.35	1.68e-08	3.73e-06	85
GO:0065004	GO:0065004	protein-DNA complex assembly	28/743	98/8135	3.13	2.52e-08	5.28e-06	98
GO:0034728	GO:0034728	nucleosome organization	26/743	87/8135	3.27	2.88e-08	5.71e-06	87
GO:0006333	GO:0006333	chromatin assembly or disassembly	26/743	90/8135	3.16	6.22e-08	1.17e-05	90
GO:0060968	GO:0060968	regulation of gene silencing	19/743	53/8135	3.93	8.54e-08	1.53e-05	53
GO:0006342	GO:0006342	chromatin silencing	17/743	44/8135	4.23	1.15e-07	1.98e-05	44
GO:0006323	GO:0006323	DNA packaging	27/743	100/8135	2.96	1.63e-07	2.67e-05	100
GO:0036158	GO:0036158	outer dynein arm assembly	9/743	13/8135	7.58	2.16e-07	3.25e-05	13
GO:0036159	GO:0036159	inner dynein arm assembly	9/743	13/8135	7.58	2.16e-07	3.25e-05	13
GO:0071824	GO:0071824	protein-DNA complex subunit organization	28/743	109/8135	2.81	3.00e-07	4.36e-05	109
GO:0000183	GO:0000183	chromatin silencing at rDNA	12/743	25/8135	5.26	5.25e-07	7.34e-05	25
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	17/743	49/8135	3.80	7.05e-07	9.51e-05	49
GO:0001539	GO:0001539	cilium or flagellum-dependent cell motility	11/743	23/8135	5.24	1.66e-06	2.09e-04	23
GO:0060285	GO:0060285	cilium-dependent cell motility	11/743	23/8135	5.24	1.66e-06	2.09e-04	23
GO:0007368	GO:0007368	determination of left/right symmetry	20/743	69/8135	3.17	1.96e-06	2.39e-04	69
GO:0016079	GO:0016079	synaptic vesicle exocytosis	22/743	81/8135	2.97	2.04e-06	2.41e-04	81
GO:0017156	GO:0017156	calcium ion regulated exocytosis	25/743	100/8135	2.74	2.22e-06	2.54e-04	100
GO:0031629	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	9/743	16/8135	6.16	2.68e-06	2.97e-04	16
GO:0071103	GO:0071103	DNA conformation change	28/743	121/8135	2.53	2.91e-06	3.13e-04	121
GO:0060964	GO:0060964	regulation of gene silencing by miRNA	14/743	38/8135	4.03	3.00e-06	3.14e-04	38
GO:0099500	GO:0099500	vesicle fusion to plasma membrane	9/743	17/8135	5.80	5.23e-06	5.33e-04	17
GO:0060147	GO:0060147	regulation of posttranscriptional gene silencing	14/743	40/8135	3.83	6.05e-06	5.72e-04	40
GO:0060966	GO:0060966	regulation of gene silencing by RNA	14/743	40/8135	3.83	6.05e-06	5.72e-04	40
GO:0030317	GO:0030317	flagellated sperm motility	18/743	62/8135	3.18	6.22e-06	5.72e-04	62
GO:0097722	GO:0097722	sperm motility	18/743	62/8135	3.18	6.22e-06	5.72e-04	62
GO:0009855	GO:0009855	determination of bilateral symmetry	20/743	75/8135	2.92	8.04e-06	7.22e-04	75
GO:0009799	GO:0009799	specification of symmetry	20/743	76/8135	2.88	9.99e-06	8.77e-04	76
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	10/743	23/8135	4.76	1.44e-05	1.21e-03	23
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	10/743	23/8135	4.76	1.44e-05	1.21e-03	23
GO:0017158	GO:0017158	regulation of calcium ion-dependent exocytosis	19/743	72/8135	2.89	1.59e-05	1.30e-03	72
GO:0035195	GO:0035195	gene silencing by miRNA	15/743	49/8135	3.35	1.82e-05	1.46e-03	49
GO:0006325	GO:0006325	chromatin organization	45/743	261/8135	1.89	1.93e-05	1.52e-03	261
GO:0048489	GO:0048489	synaptic vesicle transport	22/743	93/8135	2.59	2.31e-05	1.74e-03	93
GO:0097480	GO:0097480	establishment of synaptic vesicle localization	22/743	93/8135	2.59	2.31e-05	1.74e-03	93
GO:0045652	GO:0045652	regulation of megakaryocyte differentiation	13/743	39/8135	3.65	2.38e-05	1.76e-03	39
GO:0007269	GO:0007269	neurotransmitter secretion	25/743	114/8135	2.40	2.64e-05	1.88e-03	114
GO:0099643	GO:0099643	signal release from synapse	25/743	114/8135	2.40	2.64e-05	1.88e-03	114
GO:0045956	GO:0045956	positive regulation of calcium ion-dependent exocytosis	9/743	20/8135	4.93	2.81e-05	1.96e-03	20
GO:0097479	GO:0097479	synaptic vesicle localization	23/743	102/8135	2.47	3.45e-05	2.37e-03	102
GO:0016441	GO:0016441	posttranscriptional gene silencing	15/743	53/8135	3.10	5.11e-05	3.38e-03	53
GO:0035194	GO:0035194	posttranscriptional gene silencing by RNA	15/743	53/8135	3.10	5.11e-05	3.38e-03	53
GO:0001956	GO:0001956	positive regulation of neurotransmitter secretion	8/743	17/8135	5.15	5.37e-05	3.49e-03	17
GO:0016458	GO:0016458	gene silencing	20/743	87/8135	2.52	8.29e-05	5.16e-03	87
GO:0031630	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	6/743	10/8135	6.57	8.67e-05	5.16e-03	10
GO:0051650	GO:0051650	establishment of vesicle localization	25/743	122/8135	2.24	8.67e-05	5.16e-03	122
GO:0099504	GO:0099504	synaptic vesicle cycle	25/743	122/8135	2.24	8.67e-05	5.16e-03	122
GO:0006904	GO:0006904	vesicle docking involved in exocytosis	8/743	18/8135	4.87	8.89e-05	5.16e-03	18
GO:0016233	GO:0016233	telomere capping	8/743	18/8135	4.87	8.89e-05	5.16e-03	18
GO:0031338	GO:0031338	regulation of vesicle fusion	8/743	18/8135	4.87	8.89e-05	5.16e-03	18
GO:0051648	GO:0051648	vesicle localization	26/743	134/8135	2.12	1.62e-04	9.29e-03	134
GO:0048172	GO:0048172	regulation of short-term neuronal synaptic plasticity	6/743	11/8135	5.97	1.76e-04	9.91e-03	11
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	20/743	92/8135	2.38	1.88e-04	1.04e-02	92
GO:0098693	GO:0098693	regulation of synaptic vesicle cycle	17/743	72/8135	2.59	1.98e-04	1.08e-02	72
GO:0140029	GO:0140029	exocytic process	12/743	41/8135	3.20	2.02e-04	1.08e-02	41
GO:2000300	GO:2000300	regulation of synaptic vesicle exocytosis	14/743	53/8135	2.89	2.04e-04	1.08e-02	53
GO:0030219	GO:0030219	megakaryocyte differentiation	13/743	47/8135	3.03	2.08e-04	1.09e-02	47
GO:0099003	GO:0099003	vesicle-mediated transport in synapse	23/743	115/8135	2.19	2.40e-04	1.24e-02	115
GO:0051290	GO:0051290	protein heterotetramerization	10/743	32/8135	3.42	3.81e-04	1.94e-02	32
GO:1902803	GO:1902803	regulation of synaptic vesicle transport	14/743	57/8135	2.69	4.63e-04	2.33e-02	57
GO:0031047	GO:0031047	gene silencing by RNA	15/743	64/8135	2.57	5.04e-04	2.50e-02	64
GO:0045653	GO:0045653	negative regulation of megakaryocyte differentiation	6/743	13/8135	5.05	5.57e-04	2.73e-02	13
GO:0046928	GO:0046928	regulation of neurotransmitter secretion	16/743	72/8135	2.43	6.25e-04	3.02e-02	72
GO:0032200	GO:0032200	telomere organization	12/743	46/8135	2.86	6.50e-04	3.10e-02	46
GO:0051590	GO:0051590	positive regulation of neurotransmitter transport	9/743	29/8135	3.40	7.89e-04	3.72e-02	29
GO:0006836	GO:0006836	neurotransmitter transport	31/743	188/8135	1.81	8.22e-04	3.78e-02	188
GO:0006906	GO:0006906	vesicle fusion	10/743	35/8135	3.13	8.42e-04	3.78e-02	35
GO:0090174	GO:0090174	organelle membrane fusion	10/743	35/8135	3.13	8.42e-04	3.78e-02	35
GO:1903307	GO:1903307	positive regulation of regulated secretory pathway	10/743	35/8135	3.13	8.42e-04	3.78e-02	35
GO:0009132	GO:0009132	nucleoside diphosphate metabolic process	13/743	54/8135	2.64	8.98e-04	3.99e-02	54
GO:0048278	GO:0048278	vesicle docking	8/743	24/8135	3.65	9.10e-04	3.99e-02	24
GO:0048284	GO:0048284	organelle fusion	11/743	42/8135	2.87	1.05e-03	4.54e-02	42

GATA3_LOF_down : 12 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0043588	GO:0043588	skin development	86/1640	241/8135	1.77	9.36e-09	4.23e-05	241
GO:0070268	GO:0070268	cornification	42/1640	95/8135	2.19	8.20e-08	1.85e-04	95
GO:0008544	GO:0008544	epidermis development	91/1640	273/8135	1.65	1.44e-07	2.17e-04	273
GO:0030216	GO:0030216	keratinocyte differentiation	58/1640	162/8135	1.78	2.18e-06	2.46e-03	162
GO:0031424	GO:0031424	keratinization	45/1640	123/8135	1.81	1.57e-05	1.36e-02	123
GO:0009913	GO:0009913	epidermal cell differentiation	64/1640	195/8135	1.63	1.80e-05	1.36e-02	195
GO:0030111	GO:0030111	regulation of Wnt signaling pathway	55/1640	163/8135	1.67	2.89e-05	1.86e-02	163
GO:0071470	GO:0071470	cellular response to osmotic stress	11/1640	16/8135	3.41	3.45e-05	1.95e-02	16
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	43/1640	122/8135	1.75	6.71e-05	3.03e-02	122
GO:0016055	GO:0016055	Wnt signaling pathway	72/1640	238/8135	1.50	1.14e-04	4.31e-02	238
GO:0198738	GO:0198738	cell-cell signaling by wnt	72/1640	238/8135	1.50	1.14e-04	4.31e-02	238
GO:0051216	GO:0051216	cartilage development	49/1640	148/8135	1.64	1.32e-04	4.59e-02	148

PIK3CA_mis_up : 7 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0003341	GO:0003341	cilium movement	37/3011	46/8135	2.17	1.92e-09	8.95e-06	46
GO:0044782	GO:0044782	cilium organization	81/3011	132/8135	1.66	9.26e-09	1.94e-05	132
GO:0035082	GO:0035082	axoneme assembly	36/3011	46/8135	2.11	1.25e-08	1.94e-05	46
GO:0060271	GO:0060271	cilium assembly	75/3011	123/8135	1.65	4.81e-08	5.61e-05	123
GO:0070286	GO:0070286	axonemal dynein complex assembly	22/3011	25/8135	2.38	1.90e-07	1.77e-04	25
GO:0001578	GO:0001578	microtubule bundle formation	39/3011	62/8135	1.70	2.93e-05	1.37e-02	62
GO:0036158	GO:0036158	outer dynein arm assembly	12/3011	13/8135	2.49	5.59e-05	2.00e-02	13

PIK3CA_mis_down : 144 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0000278	GO:0000278	mitotic cell cycle	191/2566	326/8135	1.86	8.38e-25	3.70e-21	326
GO:1903047	GO:1903047	mitotic cell cycle process	164/2566	267/8135	1.95	1.66e-24	3.70e-21	267
GO:0022402	GO:0022402	cell cycle process	239/2566	470/8135	1.61	2.53e-19	3.76e-16	470
GO:0051276	GO:0051276	chromosome organization	195/2566	385/8135	1.61	1.13e-15	1.13e-12	385
GO:0044772	GO:0044772	mitotic cell cycle phase transition	101/2566	164/8135	1.95	1.27e-15	1.13e-12	164
GO:0000070	GO:0000070	mitotic sister chromatid segregation	46/2566	56/8135	2.60	6.33e-15	4.70e-12	56
GO:0044770	GO:0044770	cell cycle phase transition	105/2566	177/8135	1.88	1.30e-14	8.28e-12	177
GO:0140014	GO:0140014	mitotic nuclear division	72/2566	107/8135	2.13	2.36e-14	1.32e-11	107
GO:0000819	GO:0000819	sister chromatid segregation	52/2566	68/8135	2.42	2.67e-14	1.32e-11	68
GO:0007059	GO:0007059	chromosome segregation	76/2566	118/8135	2.04	1.54e-13	6.87e-11	118
GO:0051726	GO:0051726	regulation of cell cycle	197/2566	412/8135	1.52	1.13e-12	4.58e-10	412
GO:0051301	GO:0051301	cell division	119/2566	219/8135	1.72	1.26e-12	4.69e-10	219
GO:0000280	GO:0000280	nuclear division	107/2566	192/8135	1.77	2.11e-12	7.24e-10	192
GO:0007346	GO:0007346	regulation of mitotic cell cycle	112/2566	207/8135	1.72	8.49e-12	2.70e-09	207
GO:0071103	GO:0071103	DNA conformation change	74/2566	121/8135	1.94	1.40e-11	4.03e-09	121
GO:0048285	GO:0048285	organelle fission	111/2566	206/8135	1.71	1.49e-11	4.03e-09	206
GO:0098813	GO:0098813	nuclear chromosome segregation	67/2566	106/8135	2.00	1.54e-11	4.03e-09	106
GO:0010564	GO:0010564	regulation of cell cycle process	125/2566	243/8135	1.63	5.01e-11	1.24e-08	243
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	36/2566	47/8135	2.43	2.51e-10	5.88e-08	47
GO:0006259	GO:0006259	DNA metabolic process	145/2566	301/8135	1.53	6.55e-10	1.46e-07	301
GO:0006260	GO:0006260	DNA replication	50/2566	77/8135	2.06	1.52e-09	3.22e-07	77
GO:0007052	GO:0007052	mitotic spindle organization	30/2566	39/8135	2.44	6.84e-09	1.39e-06	39
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	65/2566	113/8135	1.82	8.57e-09	1.66e-06	113
GO:0007051	GO:0007051	spindle organization	36/2566	51/8135	2.24	1.08e-08	2.01e-06	51
GO:0006261	GO:0006261	DNA-dependent DNA replication	31/2566	42/8135	2.34	2.10e-08	3.74e-06	42
GO:1901987	GO:1901987	regulation of cell cycle phase transition	69/2566	125/8135	1.75	3.04e-08	5.21e-06	125
GO:0051983	GO:0051983	regulation of chromosome segregation	27/2566	35/8135	2.45	3.59e-08	5.71e-06	35
GO:0000075	GO:0000075	cell cycle checkpoint	43/2566	67/8135	2.03	3.59e-08	5.71e-06	67
GO:0032392	GO:0032392	DNA geometric change	20/2566	23/8135	2.76	5.52e-08	8.49e-06	23
GO:0007088	GO:0007088	regulation of mitotic nuclear division	48/2566	79/8135	1.93	7.38e-08	1.10e-05	79
GO:0045787	GO:0045787	positive regulation of cell cycle	85/2566	166/8135	1.62	8.39e-08	1.20e-05	166
GO:0032508	GO:0032508	DNA duplex unwinding	18/2566	20/8135	2.85	8.61e-08	1.20e-05	20
GO:0071824	GO:0071824	protein-DNA complex subunit organization	61/2566	109/8135	1.77	9.81e-08	1.32e-05	109
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	50/2566	84/8135	1.89	1.01e-07	1.32e-05	84
GO:0006323	GO:0006323	DNA packaging	57/2566	100/8135	1.81	1.09e-07	1.39e-05	100
GO:0044843	GO:0044843	cell cycle G1/S phase transition	53/2566	91/8135	1.85	1.15e-07	1.43e-05	91
GO:0045786	GO:0045786	negative regulation of cell cycle	103/2566	212/8135	1.54	1.20e-07	1.45e-05	212
GO:0065004	GO:0065004	protein-DNA complex assembly	56/2566	98/8135	1.81	1.25e-07	1.47e-05	98
GO:0044839	GO:0044839	cell cycle G2/M phase transition	45/2566	74/8135	1.93	1.82e-07	2.08e-05	74
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	20/2566	24/8135	2.64	2.33e-07	2.39e-05	24
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	20/2566	24/8135	2.64	2.33e-07	2.39e-05	24
GO:0051306	GO:0051306	mitotic sister chromatid separation	20/2566	24/8135	2.64	2.33e-07	2.39e-05	24
GO:0006281	GO:0006281	DNA repair	69/2566	130/8135	1.68	2.37e-07	2.39e-05	130
GO:0034502	GO:0034502	protein localization to chromosome	17/2566	19/8135	2.84	2.47e-07	2.39e-05	19
GO:0051310	GO:0051310	metaphase plate congression	17/2566	19/8135	2.84	2.47e-07	2.39e-05	19
GO:0006302	GO:0006302	double-strand break repair	47/2566	79/8135	1.89	2.49e-07	2.39e-05	79
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	42/2566	68/8135	1.96	2.52e-07	2.39e-05	68
GO:0010948	GO:0010948	negative regulation of cell cycle process	54/2566	95/8135	1.80	2.66e-07	2.47e-05	95
GO:0051783	GO:0051783	regulation of nuclear division	54/2566	96/8135	1.78	4.24e-07	3.85e-05	96
GO:0051304	GO:0051304	chromosome separation	26/2566	36/8135	2.29	6.08e-07	5.42e-05	36
GO:0051321	GO:0051321	meiotic cell cycle	73/2566	143/8135	1.62	7.95e-07	6.95e-05	143
GO:1905818	GO:1905818	regulation of chromosome separation	20/2566	25/8135	2.54	8.17e-07	7.00e-05	25
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	34/2566	53/8135	2.03	9.92e-07	8.09e-05	53
GO:0034508	GO:0034508	centromere complex assembly	21/2566	27/8135	2.47	9.97e-07	8.09e-05	27
GO:0006270	GO:0006270	DNA replication initiation	14/2566	15/8135	2.96	9.98e-07	8.09e-05	15
GO:0051784	GO:0051784	negative regulation of nuclear division	22/2566	29/8135	2.41	1.15e-06	9.16e-05	29
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	31/2566	47/8135	2.09	1.23e-06	9.58e-05	47
GO:0031497	GO:0031497	chromatin assembly	48/2566	85/8135	1.79	1.58e-06	1.22e-04	85
GO:0090068	GO:0090068	positive regulation of cell cycle process	61/2566	116/8135	1.67	1.78e-06	1.34e-04	116
GO:0006333	GO:0006333	chromatin assembly or disassembly	50/2566	90/8135	1.76	1.86e-06	1.38e-04	90
GO:0032200	GO:0032200	telomere organization	30/2566	46/8135	2.07	2.60e-06	1.90e-04	46
GO:0006342	GO:0006342	chromatin silencing	29/2566	44/8135	2.09	2.78e-06	1.95e-04	44
GO:0006334	GO:0006334	nucleosome assembly	44/2566	77/8135	1.81	2.79e-06	1.95e-04	77
GO:0033045	GO:0033045	regulation of sister chromatid segregation	21/2566	28/8135	2.38	2.80e-06	1.95e-04	28
GO:0007080	GO:0007080	mitotic metaphase plate congression	13/2566	14/8135	2.94	2.97e-06	2.04e-04	14
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/2566	19/8135	2.67	3.15e-06	2.10e-04	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/2566	19/8135	2.67	3.15e-06	2.10e-04	19
GO:0034728	GO:0034728	nucleosome organization	48/2566	87/8135	1.75	3.88e-06	2.51e-04	87
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	17/2566	21/8135	2.57	4.29e-06	2.73e-04	21
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	31/2566	49/8135	2.01	4.60e-06	2.89e-04	49
GO:1903046	GO:1903046	meiotic cell cycle process	58/2566	112/8135	1.64	5.97e-06	3.70e-04	112
GO:0031055	GO:0031055	chromatin remodeling at centromere	19/2566	25/8135	2.41	6.13e-06	3.74e-04	25
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/2566	18/8135	2.64	8.50e-06	4.98e-04	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/2566	18/8135	2.64	8.50e-06	4.98e-04	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/2566	18/8135	2.64	8.50e-06	4.98e-04	18
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/2566	10/8135	3.17	9.63e-06	5.58e-04	10
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	16/2566	20/8135	2.54	1.11e-05	6.36e-04	20
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	49/2566	92/8135	1.69	1.15e-05	6.49e-04	92
GO:0000910	GO:0000910	cytokinesis	33/2566	55/8135	1.90	1.19e-05	6.55e-04	55
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	33/2566	55/8135	1.90	1.19e-05	6.55e-04	55
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	17/2566	22/8135	2.45	1.33e-05	7.24e-04	22
GO:0140013	GO:0140013	meiotic nuclear division	55/2566	107/8135	1.63	1.37e-05	7.28e-04	107
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	18/2566	24/8135	2.38	1.50e-05	7.66e-04	24
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	18/2566	24/8135	2.38	1.50e-05	7.66e-04	24
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	18/2566	24/8135	2.38	1.50e-05	7.66e-04	24
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	23/2566	34/8135	2.14	1.59e-05	8.07e-04	34
GO:0000281	GO:0000281	mitotic cytokinesis	20/2566	28/8135	2.26	1.66e-05	8.31e-04	28
GO:0031570	GO:0031570	DNA integrity checkpoint	28/2566	45/8135	1.97	2.10e-05	1.03e-03	45
GO:2001251	GO:2001251	negative regulation of chromosome organization	28/2566	45/8135	1.97	2.10e-05	1.03e-03	45
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	52/2566	101/8135	1.63	2.21e-05	1.07e-03	101
GO:0007062	GO:0007062	sister chromatid cohesion	14/2566	17/8135	2.61	2.27e-05	1.09e-03	17
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	11/2566	12/8135	2.91	2.59e-05	1.19e-03	12
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	11/2566	12/8135	2.91	2.59e-05	1.19e-03	12
GO:0006310	GO:0006310	DNA recombination	53/2566	104/8135	1.62	2.68e-05	1.22e-03	104
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	16/2566	21/8135	2.42	3.30e-05	1.49e-03	21
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	17/2566	23/8135	2.34	3.60e-05	1.59e-03	23
GO:0061641	GO:0061641	CENP-A containing chromatin organization	17/2566	23/8135	2.34	3.60e-05	1.59e-03	23
GO:0043486	GO:0043486	histone exchange	19/2566	27/8135	2.23	3.81e-05	1.66e-03	27
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	27/2566	44/8135	1.95	4.22e-05	1.81e-03	44
GO:0000725	GO:0000725	recombinational repair	27/2566	44/8135	1.95	4.22e-05	1.81e-03	44
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	12/2566	14/8135	2.72	4.37e-05	1.84e-03	14
GO:0044786	GO:0044786	cell cycle DNA replication	12/2566	14/8135	2.72	4.37e-05	1.84e-03	14
GO:0000723	GO:0000723	telomere maintenance	23/2566	36/8135	2.03	6.35e-05	2.64e-03	36
GO:0016458	GO:0016458	gene silencing	45/2566	87/8135	1.64	6.70e-05	2.77e-03	87
GO:0033044	GO:0033044	regulation of chromosome organization	49/2566	97/8135	1.60	7.13e-05	2.91e-03	97
GO:0007098	GO:0007098	centrosome cycle	21/2566	32/8135	2.08	7.45e-05	3.02e-03	32
GO:0090307	GO:0090307	mitotic spindle assembly	15/2566	20/8135	2.38	8.07e-05	3.24e-03	20
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	36/2566	66/8135	1.73	8.54e-05	3.37e-03	66
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	36/2566	66/8135	1.73	8.54e-05	3.37e-03	66
GO:0006338	GO:0006338	chromatin remodeling	33/2566	59/8135	1.77	8.67e-05	3.39e-03	59
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	22/2566	35/8135	1.99	1.31e-04	5.07e-03	35
GO:0060968	GO:0060968	regulation of gene silencing	30/2566	53/8135	1.79	1.35e-04	5.14e-03	53
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	33/2566	60/8135	1.74	1.35e-04	5.14e-03	60
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:0031577	GO:0031577	spindle checkpoint	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	12/2566	15/8135	2.54	1.56e-04	5.63e-03	15
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	25/2566	42/8135	1.89	1.63e-04	5.87e-03	42
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	19/2566	29/8135	2.08	1.71e-04	6.04e-03	29
GO:0051225	GO:0051225	spindle assembly	19/2566	29/8135	2.08	1.71e-04	6.04e-03	29
GO:0050000	GO:0050000	chromosome localization	18/2566	27/8135	2.11	1.83e-04	6.36e-03	27
GO:0051303	GO:0051303	establishment of chromosome localization	18/2566	27/8135	2.11	1.83e-04	6.36e-03	27
GO:0000183	GO:0000183	chromatin silencing at rDNA	17/2566	25/8135	2.16	1.92e-04	6.65e-03	25
GO:0033260	GO:0033260	nuclear DNA replication	10/2566	12/8135	2.64	3.25e-04	1.08e-02	12
GO:0070507	GO:0070507	regulation of microtubule cytoskeleton organization	34/2566	65/8135	1.66	3.86e-04	1.27e-02	65
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	36/2566	71/8135	1.61	5.74e-04	1.87e-02	71
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	15/2566	23/8135	2.07	9.08e-04	2.87e-02	23
GO:0006882	GO:0006882	cellular zinc ion homeostasis	15/2566	23/8135	2.07	9.08e-04	2.87e-02	23
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	15/2566	23/8135	2.07	9.08e-04	2.87e-02	23
GO:0061982	GO:0061982	meiosis I cell cycle process	37/2566	75/8135	1.56	9.44e-04	2.96e-02	75
GO:0051782	GO:0051782	negative regulation of cell division	10/2566	13/8135	2.44	1.01e-03	3.08e-02	13
GO:0016441	GO:0016441	posttranscriptional gene silencing	28/2566	53/8135	1.67	1.01e-03	3.08e-02	53
GO:0035194	GO:0035194	posttranscriptional gene silencing by RNA	28/2566	53/8135	1.67	1.01e-03	3.08e-02	53
GO:0045132	GO:0045132	meiotic chromosome segregation	28/2566	53/8135	1.67	1.01e-03	3.08e-02	53
GO:0061351	GO:0061351	neural precursor cell proliferation	42/2566	88/8135	1.51	1.04e-03	3.16e-02	88
GO:0006890	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	12/2566	17/8135	2.24	1.07e-03	3.23e-02	17
GO:0031023	GO:0031023	microtubule organizing center organization	21/2566	37/8135	1.80	1.29e-03	3.83e-02	37
GO:0035195	GO:0035195	gene silencing by miRNA	26/2566	49/8135	1.68	1.39e-03	4.10e-02	49
GO:0006275	GO:0006275	regulation of DNA replication	19/2566	33/8135	1.83	1.73e-03	4.94e-02	33
GO:0044774	GO:0044774	mitotic DNA integrity checkpoint	19/2566	33/8135	1.83	1.73e-03	4.94e-02	33
GO:0060147	GO:0060147	regulation of posttranscriptional gene silencing	22/2566	40/8135	1.74	1.74e-03	4.94e-02	40
GO:0060966	GO:0060966	regulation of gene silencing by RNA	22/2566	40/8135	1.74	1.74e-03	4.94e-02	40

Summary:
Mutation_status	TP53_LOF_up	TP53_LOF_down	TP53_mis_up	TP53_mis_down	CDH1_LOF_up
Signif_GO_terms	143	6	142	7	7
Mutation_status	CDH1_LOF_down	GATA3_LOF_up	GATA3_LOF_down	PIK3CA_mis_up	PIK3CA_mis_down
Signif_GO_terms	263	87	12	7	144