1 Data Description

References: Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.

Data source:
FireBrowse TCGA BRCA Archives.

Samples:
TCGA breast invasive carcinoma (BRCA) tumor samples in file “illuminahiseq_rnaseq-gene_expression”.
To avoid possible confounding due to gender and race, we confined our study samples to be only from female Caucasian subjects.
In addition, only samples with somatic mutation annotation were kept, resulted in 573 samples.

Genes:
Only the top 10k variable genes in samples of consideration were kept. (Variance was calculated based on the TMM-normalized log2(CPM) data.)

Normalization:
Raw counts normalized by TMM using edgeR, converted to log2(CPM), then corrected for subject age and tumor purity. The corrected and scaled expression data were used as input for subsequent factor analysis.

Perturbations:
Somatic mutation status of selected frequently mutated driver genes (TP53, CDH1, GATA3, MAP3K1, PIK3CA).
Mutations were classified into 2 types: missense mutations and loss of function (LOF) mutations.

Number of samples that harbor each type of mutation (out of all 573)
Mutation	TP53_LOF	TP53_mis	CDH1_LOF	CDH1_mis	GATA3_LOF
Num_cells	71	100	34	8	58
Mutation	GATA3_mis	MAP3K1_LOF	MAP3K1_mis	PIK3CA_LOF	PIK3CA_mis
Num_cells	5	37	10	6	187

2 Guided results

Here, our “guide”, \(G\) matrix, consists of the somatic mutation status (missense and LOF separated) of top 5 driver genes across samples.

We specified 20 factors in our model. In each case, Gibbs sampling was conducted for 2000 iterations, and the posterior mean estimates were averaged over the last 500 iterations.

2.1 SVD Initialization

2.1.1 Local False Sign Rate (LFSR)

For a given GSFA inference result, we can estimate the effect a certain KO condition \(m\) has on the expression of gene \(j\) by computing the LFSR of \(\beta_{m\cdot} \cdot W_{j\cdot}\).

GSFA, # of genes that passed LFSR cutoff of 0.05:
KO	TP53_LOF	TP53_mis	CDH1_LOF	CDH1_mis	GATA3_LOF
Num_genes	7349	7173	3769	0	3583
KO	GATA3_mis	MAP3K1_LOF	MAP3K1_mis	PIK3CA_LOF	PIK3CA_mis
Num_genes	0	119	0	0	6699

2.1.2 Factor ~ KO Beta PIP

2.1.3 Factor ~ KO Posterior Association

2.1.4 Beta PIP vs P-Value

2.1.5 Correlation btw Factors

3 Gene Ontology Enrichment Analysis

Statistical test: hypergeometric test;

GO category: Biological Process.

3.1 GO enrichment per factor

Target: Genes w/ PIP > 0.95 in each factor;
Backgroud: all 10000 genes used in factor analysis.

GO terms that passed over-representation test fold change \(\geq\) 1.5 and q value \(<\) 0.05:

Factor 2 : 11 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030199	GO:0030199	collagen fibril organization	35/4365	41/8380	1.64	7.68e-06	0.00181	41
GO:1900449	GO:1900449	regulation of glutamate receptor signaling pathway	30/4365	34/8380	1.69	8.66e-06	0.00194	34
GO:0060996	GO:0060996	dendritic spine development	41/4365	51/8380	1.54	2.51e-05	0.00417	51
GO:0006415	GO:0006415	translational termination	12/4365	12/8380	1.92	3.96e-04	0.03225	12
GO:0051646	GO:0051646	mitochondrion localization	15/4365	16/8380	1.80	4.57e-04	0.03469	16
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	26/4365	32/8380	1.56	6.01e-04	0.03895	32
GO:0010714	GO:0010714	positive regulation of collagen metabolic process	17/4365	19/8380	1.72	6.69e-04	0.04080	19
GO:0070125	GO:0070125	mitochondrial translational elongation	11/4365	11/8380	1.92	7.61e-04	0.04262	11
GO:0070126	GO:0070126	mitochondrial translational termination	11/4365	11/8380	1.92	7.61e-04	0.04262	11
GO:0140053	GO:0140053	mitochondrial gene expression	14/4365	15/8380	1.79	8.27e-04	0.04518	15
GO:0060997	GO:0060997	dendritic spine morphogenesis	29/4365	37/8380	1.50	8.82e-04	0.04701	37

Factor 3 : 5 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0006364	GO:0006364	rRNA processing	26/5268	27/8380	1.53	5.99e-05	0.0179	27
GO:0006613	GO:0006613	cotranslational protein targeting to membrane	19/5268	19/8380	1.59	1.46e-04	0.0251	19
GO:0006614	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	19/5268	19/8380	1.59	1.46e-04	0.0251	19
GO:0007257	GO:0007257	activation of JUN kinase activity	23/5268	24/8380	1.52	2.17e-04	0.0286	24
GO:0032148	GO:0032148	activation of protein kinase B activity	18/5268	18/8380	1.59	2.33e-04	0.0289	18

Factor 4 : 125 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030198	GO:0030198	extracellular matrix organization	204/2981	290/8380	1.98	1.59e-34	6.98e-31	290
GO:0043062	GO:0043062	extracellular structure organization	218/2981	326/8380	1.88	1.05e-31	2.29e-28	326
GO:0001501	GO:0001501	skeletal system development	201/2981	351/8380	1.61	2.27e-17	3.31e-14	351
GO:0030199	GO:0030199	collagen fibril organization	35/2981	41/8380	2.40	6.19e-11	3.38e-08	41
GO:0001503	GO:0001503	ossification	137/2981	252/8380	1.53	4.91e-10	2.39e-07	252
GO:0061448	GO:0061448	connective tissue development	107/2981	190/8380	1.58	3.01e-09	8.78e-07	190
GO:0051216	GO:0051216	cartilage development	90/2981	154/8380	1.64	4.59e-09	1.19e-06	154
GO:0048705	GO:0048705	skeletal system morphogenesis	98/2981	172/8380	1.60	6.11e-09	1.48e-06	172
GO:0090130	GO:0090130	tissue migration	99/2981	176/8380	1.58	1.28e-08	2.94e-06	176
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	30/2981	37/8380	2.28	1.72e-08	3.42e-06	37
GO:0010631	GO:0010631	epithelial cell migration	95/2981	169/8380	1.58	2.62e-08	4.99e-06	169
GO:0090287	GO:0090287	regulation of cellular response to growth factor stimulus	94/2981	167/8380	1.58	2.84e-08	5.18e-06	167
GO:0010810	GO:0010810	regulation of cell-substrate adhesion	79/2981	135/8380	1.65	3.71e-08	6.50e-06	135
GO:0090132	GO:0090132	epithelium migration	95/2981	170/8380	1.57	3.89e-08	6.55e-06	170
GO:0007044	GO:0007044	cell-substrate junction assembly	40/2981	57/8380	1.97	1.02e-07	1.60e-05	57
GO:0034330	GO:0034330	cell junction organization	96/2981	175/8380	1.54	1.12e-07	1.69e-05	175
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	22/2981	26/8380	2.38	3.63e-07	5.30e-05	26
GO:0006023	GO:0006023	aminoglycan biosynthetic process	48/2981	75/8380	1.80	4.62e-07	6.39e-05	75
GO:0060348	GO:0060348	bone development	79/2981	141/8380	1.58	4.67e-07	6.39e-05	141
GO:0034329	GO:0034329	cell junction assembly	78/2981	139/8380	1.58	5.07e-07	6.72e-05	139
GO:0002062	GO:0002062	chondrocyte differentiation	54/2981	89/8380	1.71	1.11e-06	1.35e-04	89
GO:0010632	GO:0010632	regulation of epithelial cell migration	72/2981	128/8380	1.58	1.22e-06	1.45e-04	128
GO:0006024	GO:0006024	glycosaminoglycan biosynthetic process	46/2981	73/8380	1.77	1.53e-06	1.76e-04	73
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	52/2981	87/8380	1.68	3.30e-06	3.53e-04	87
GO:0032330	GO:0032330	regulation of chondrocyte differentiation	27/2981	37/8380	2.05	3.84e-06	4.00e-04	37
GO:0061035	GO:0061035	regulation of cartilage development	33/2981	49/8380	1.89	5.70e-06	5.55e-04	49
GO:0043542	GO:0043542	endothelial cell migration	67/2981	121/8380	1.56	5.95e-06	5.66e-04	121
GO:0042476	GO:0042476	odontogenesis	56/2981	97/8380	1.62	6.33e-06	5.77e-04	97
GO:0032963	GO:0032963	collagen metabolic process	46/2981	76/8380	1.70	7.52e-06	6.72e-04	76
GO:0090288	GO:0090288	negative regulation of cellular response to growth factor stimulus	53/2981	91/8380	1.64	7.83e-06	6.85e-04	91
GO:0017015	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	37/2981	58/8380	1.79	1.07e-05	9.16e-04	58
GO:0001935	GO:0001935	endothelial cell proliferation	54/2981	94/8380	1.61	1.13e-05	9.48e-04	94
GO:0010811	GO:0010811	positive regulation of cell-substrate adhesion	48/2981	82/8380	1.65	1.73e-05	1.43e-03	82
GO:0022617	GO:0022617	extracellular matrix disassembly	38/2981	61/8380	1.75	1.82e-05	1.48e-03	61
GO:1903844	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	37/2981	59/8380	1.76	1.89e-05	1.50e-03	59
GO:1903053	GO:1903053	regulation of extracellular matrix organization	20/2981	26/8380	2.16	1.99e-05	1.55e-03	26
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	48/2981	83/8380	1.63	2.69e-05	2.00e-03	83
GO:0051893	GO:0051893	regulation of focal adhesion assembly	23/2981	32/8380	2.02	3.07e-05	2.13e-03	32
GO:0090109	GO:0090109	regulation of cell-substrate junction assembly	23/2981	32/8380	2.02	3.07e-05	2.13e-03	32
GO:0031581	GO:0031581	hemidesmosome assembly	10/2981	10/8380	2.81	3.21e-05	2.19e-03	10
GO:0002040	GO:0002040	sprouting angiogenesis	45/2981	77/8380	1.64	3.33e-05	2.19e-03	77
GO:1903391	GO:1903391	regulation of adherens junction organization	24/2981	34/8380	1.98	3.34e-05	2.19e-03	34
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	42/2981	71/8380	1.66	4.06e-05	2.57e-03	71
GO:0060349	GO:0060349	bone morphogenesis	48/2981	84/8380	1.61	4.13e-05	2.58e-03	84
GO:0060021	GO:0060021	roof of mouth development	39/2981	65/8380	1.69	4.87e-05	2.84e-03	65
GO:0002526	GO:0002526	acute inflammatory response	62/2981	116/8380	1.50	5.58e-05	3.02e-03	116
GO:0002673	GO:0002673	regulation of acute inflammatory response	43/2981	74/8380	1.63	5.98e-05	3.19e-03	74
GO:0006022	GO:0006022	aminoglycan metabolic process	59/2981	110/8380	1.51	7.34e-05	3.83e-03	110
GO:0010594	GO:0010594	regulation of endothelial cell migration	50/2981	90/8380	1.56	7.86e-05	4.00e-03	90
GO:0030203	GO:0030203	glycosaminoglycan metabolic process	56/2981	104/8380	1.51	9.64e-05	4.80e-03	104
GO:0016525	GO:0016525	negative regulation of angiogenesis	40/2981	69/8380	1.63	1.15e-04	5.61e-03	69
GO:1901343	GO:1901343	negative regulation of vasculature development	45/2981	80/8380	1.58	1.19e-04	5.73e-03	80
GO:0007179	GO:0007179	transforming growth factor beta receptor signaling pathway	52/2981	96/8380	1.52	1.38e-04	6.31e-03	96
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	35/2981	59/8380	1.67	1.62e-04	7.18e-03	59
GO:0002313	GO:0002313	mature B cell differentiation involved in immune response	12/2981	14/8380	2.41	1.67e-04	7.30e-03	14
GO:0043534	GO:0043534	blood vessel endothelial cell migration	39/2981	68/8380	1.61	1.92e-04	8.22e-03	68
GO:0034332	GO:0034332	adherens junction organization	47/2981	86/8380	1.54	2.16e-04	9.18e-03	86
GO:0007045	GO:0007045	cell-substrate adherens junction assembly	28/2981	45/8380	1.75	2.37e-04	9.86e-03	45
GO:0048041	GO:0048041	focal adhesion assembly	28/2981	45/8380	1.75	2.37e-04	9.86e-03	45
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	36/2981	62/8380	1.63	2.40e-04	9.89e-03	62
GO:0007229	GO:0007229	integrin-mediated signaling pathway	41/2981	73/8380	1.58	2.47e-04	1.01e-02	73
GO:0097756	GO:0097756	negative regulation of blood vessel diameter	35/2981	60/8380	1.64	2.57e-04	1.04e-02	60
GO:0002042	GO:0002042	cell migration involved in sprouting angiogenesis	24/2981	37/8380	1.82	2.65e-04	1.06e-02	37
GO:0032964	GO:0032964	collagen biosynthetic process	22/2981	33/8380	1.87	2.67e-04	1.06e-02	33
GO:0042310	GO:0042310	vasoconstriction	34/2981	58/8380	1.65	2.76e-04	1.08e-02	58
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	30/2981	50/8380	1.69	3.58e-04	1.29e-02	50
GO:1902547	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	11/2981	13/8380	2.38	4.06e-04	1.42e-02	13
GO:0006939	GO:0006939	smooth muscle contraction	44/2981	81/8380	1.53	4.06e-04	1.42e-02	81
GO:0010765	GO:0010765	positive regulation of sodium ion transport	16/2981	22/8380	2.04	4.24e-04	1.45e-02	22
GO:0060840	GO:0060840	artery development	34/2981	59/8380	1.62	4.31e-04	1.46e-02	59
GO:0030204	GO:0030204	chondroitin sulfate metabolic process	17/2981	24/8380	1.99	4.61e-04	1.55e-02	24
GO:0001656	GO:0001656	metanephros development	42/2981	77/8380	1.53	4.86e-04	1.58e-02	77
GO:0050654	GO:0050654	chondroitin sulfate proteoglycan metabolic process	18/2981	26/8380	1.95	4.87e-04	1.58e-02	26
GO:0090049	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	18/2981	26/8380	1.95	4.87e-04	1.58e-02	26
GO:0072210	GO:0072210	metanephric nephron development	23/2981	36/8380	1.80	4.93e-04	1.59e-02	36
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	21/2981	32/8380	1.84	5.09e-04	1.63e-02	32
GO:0042698	GO:0042698	ovulation cycle	30/2981	51/8380	1.65	5.76e-04	1.79e-02	51
GO:0007272	GO:0007272	ensheathment of neurons	40/2981	73/8380	1.54	5.81e-04	1.79e-02	73
GO:0008366	GO:0008366	axon ensheathment	40/2981	73/8380	1.54	5.81e-04	1.79e-02	73
GO:0032288	GO:0032288	myelin assembly	9/2981	10/8380	2.53	6.16e-04	1.86e-02	10
GO:0090101	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	39/2981	71/8380	1.54	6.35e-04	1.86e-02	71
GO:1903510	GO:1903510	mucopolysaccharide metabolic process	39/2981	71/8380	1.54	6.35e-04	1.86e-02	71
GO:0002335	GO:0002335	mature B cell differentiation	13/2981	17/8380	2.15	6.96e-04	1.98e-02	17
GO:0030206	GO:0030206	chondroitin sulfate biosynthetic process	13/2981	17/8380	2.15	6.96e-04	1.98e-02	17
GO:0032331	GO:0032331	negative regulation of chondrocyte differentiation	13/2981	17/8380	2.15	6.96e-04	1.98e-02	17
GO:0019229	GO:0019229	regulation of vasoconstriction	27/2981	45/8380	1.69	7.00e-04	1.98e-02	45
GO:1901888	GO:1901888	regulation of cell junction assembly	27/2981	45/8380	1.69	7.00e-04	1.98e-02	45
GO:0070613	GO:0070613	regulation of protein processing	41/2981	76/8380	1.52	7.62e-04	2.11e-02	76
GO:0050650	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	14/2981	19/8380	2.07	8.03e-04	2.18e-02	19
GO:0085029	GO:0085029	extracellular matrix assembly	14/2981	19/8380	2.07	8.03e-04	2.18e-02	19
GO:0050918	GO:0050918	positive chemotaxis	31/2981	54/8380	1.61	8.35e-04	2.25e-02	54
GO:0030512	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	23/2981	37/8380	1.75	8.66e-04	2.31e-02	37
GO:0035904	GO:0035904	aorta development	22/2981	35/8380	1.77	9.02e-04	2.37e-02	35
GO:0042552	GO:0042552	myelination	39/2981	72/8380	1.52	9.15e-04	2.38e-02	72
GO:0050926	GO:0050926	regulation of positive chemotaxis	16/2981	23/8380	1.96	9.33e-04	2.41e-02	23
GO:0071634	GO:0071634	regulation of transforming growth factor beta production	17/2981	25/8380	1.91	9.64e-04	2.41e-02	25
GO:0010712	GO:0010712	regulation of collagen metabolic process	19/2981	29/8380	1.84	9.73e-04	2.41e-02	29
GO:0048566	GO:0048566	embryonic digestive tract development	19/2981	29/8380	1.84	9.73e-04	2.41e-02	29
GO:0051580	GO:0051580	regulation of neurotransmitter uptake	10/2981	12/8380	2.34	9.75e-04	2.41e-02	12
GO:1900746	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	10/2981	12/8380	2.34	9.75e-04	2.41e-02	12
GO:0048260	GO:0048260	positive regulation of receptor-mediated endocytosis	18/2981	27/8380	1.87	9.76e-04	2.41e-02	27
GO:0034333	GO:0034333	adherens junction assembly	28/2981	48/8380	1.64	1.05e-03	2.53e-02	48
GO:0042475	GO:0042475	odontogenesis of dentin-containing tooth	36/2981	66/8380	1.53	1.20e-03	2.84e-02	66
GO:0006027	GO:0006027	glycosaminoglycan catabolic process	26/2981	44/8380	1.66	1.21e-03	2.84e-02	44
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	25/2981	42/8380	1.67	1.29e-03	2.94e-02	42
GO:0002063	GO:0002063	chondrocyte development	23/2981	38/8380	1.70	1.46e-03	3.25e-02	38
GO:1903845	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	23/2981	38/8380	1.70	1.46e-03	3.25e-02	38
GO:0030038	GO:0030038	contractile actin filament bundle assembly	29/2981	51/8380	1.60	1.50e-03	3.28e-02	51
GO:0043149	GO:0043149	stress fiber assembly	29/2981	51/8380	1.60	1.50e-03	3.28e-02	51
GO:0071880	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	12/2981	16/8380	2.11	1.52e-03	3.29e-02	16
GO:1903010	GO:1903010	regulation of bone development	12/2981	16/8380	2.11	1.52e-03	3.29e-02	16
GO:0044273	GO:0044273	sulfur compound catabolic process	22/2981	36/8380	1.72	1.55e-03	3.33e-02	36
GO:0035136	GO:0035136	forelimb morphogenesis	21/2981	34/8380	1.74	1.63e-03	3.48e-02	34
GO:0035987	GO:0035987	endodermal cell differentiation	21/2981	34/8380	1.74	1.63e-03	3.48e-02	34
GO:0014829	GO:0014829	vascular smooth muscle contraction	13/2981	18/8380	2.03	1.69e-03	3.59e-02	18
GO:0050772	GO:0050772	positive regulation of axonogenesis	27/2981	47/8380	1.61	1.76e-03	3.69e-02	47
GO:0006929	GO:0006929	substrate-dependent cell migration	14/2981	20/8380	1.97	1.80e-03	3.77e-02	20
GO:0060976	GO:0060976	coronary vasculature development	18/2981	28/8380	1.81	1.83e-03	3.79e-02	28
GO:0071526	GO:0071526	semaphorin-plexin signaling pathway	18/2981	28/8380	1.81	1.83e-03	3.79e-02	28
GO:0050927	GO:0050927	positive regulation of positive chemotaxis	15/2981	22/8380	1.92	1.86e-03	3.79e-02	22
GO:0061036	GO:0061036	positive regulation of cartilage development	15/2981	22/8380	1.92	1.86e-03	3.79e-02	22
GO:0010812	GO:0010812	negative regulation of cell-substrate adhesion	24/2981	41/8380	1.65	2.21e-03	4.33e-02	41
GO:0046849	GO:0046849	bone remodeling	33/2981	61/8380	1.52	2.27e-03	4.42e-02	61
GO:0030449	GO:0030449	regulation of complement activation	23/2981	39/8380	1.66	2.37e-03	4.57e-02	39
GO:0048709	GO:0048709	oligodendrocyte differentiation	32/2981	59/8380	1.52	2.49e-03	4.75e-02	59

Factor 5 : 914 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0046649	GO:0046649	lymphocyte activation	224/1216	416/8380	3.71	2.47e-84	8.79e-81	416
GO:0002250	GO:0002250	adaptive immune response	169/1216	270/8380	4.31	9.56e-77	1.70e-73	270
GO:0050778	GO:0050778	positive regulation of immune response	218/1216	443/8380	3.39	3.38e-72	4.00e-69	443
GO:0002443	GO:0002443	leukocyte mediated immunity	204/1216	435/8380	3.23	1.01e-62	9.01e-60	435
GO:0002694	GO:0002694	regulation of leukocyte activation	174/1216	334/8380	3.59	7.13e-62	5.07e-59	334
GO:0050865	GO:0050865	regulation of cell activation	182/1216	362/8380	3.46	1.21e-61	7.20e-59	362
GO:0042110	GO:0042110	T cell activation	164/1216	306/8380	3.69	1.49e-60	7.58e-58	306
GO:0002263	GO:0002263	cell activation involved in immune response	180/1216	381/8380	3.26	1.17e-55	5.21e-53	381
GO:0002366	GO:0002366	leukocyte activation involved in immune response	179/1216	378/8380	3.26	1.57e-55	6.22e-53	378
GO:0002764	GO:0002764	immune response-regulating signaling pathway	153/1216	291/8380	3.62	6.38e-55	2.27e-52	291
GO:0002253	GO:0002253	activation of immune response	160/1216	321/8380	3.43	2.58e-53	8.33e-51	321
GO:0002757	GO:0002757	immune response-activating signal transduction	144/1216	269/8380	3.69	6.18e-53	1.83e-50	269
GO:0051249	GO:0051249	regulation of lymphocyte activation	146/1216	276/8380	3.65	8.29e-53	2.27e-50	276
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	123/1216	207/8380	4.09	6.35e-52	1.61e-49	207
GO:0001816	GO:0001816	cytokine production	195/1216	459/8380	2.93	2.57e-51	6.08e-49	459
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	114/1216	185/8380	4.25	1.92e-50	4.27e-48	185
GO:0050867	GO:0050867	positive regulation of cell activation	125/1216	220/8380	3.92	9.69e-50	2.03e-47	220
GO:0002696	GO:0002696	positive regulation of leukocyte activation	122/1216	212/8380	3.97	2.27e-49	4.48e-47	212
GO:0002521	GO:0002521	leukocyte differentiation	154/1216	320/8380	3.32	1.00e-48	1.88e-46	320
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	191/1216	465/8380	2.83	1.59e-47	2.83e-45	465
GO:0002274	GO:0002274	myeloid leukocyte activation	164/1216	362/8380	3.12	1.84e-47	3.11e-45	362
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	125/1216	231/8380	3.73	1.43e-46	2.32e-44	231
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	107/1216	180/8380	4.10	3.44e-45	5.32e-43	180
GO:0050863	GO:0050863	regulation of T cell activation	118/1216	217/8380	3.75	2.99e-44	4.43e-42	217
GO:0001817	GO:0001817	regulation of cytokine production	173/1216	415/8380	2.87	5.96e-44	8.47e-42	415
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	81/1216	118/8380	4.73	3.27e-41	4.47e-39	118
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	95/1216	157/8380	4.17	4.25e-41	5.60e-39	157
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	111/1216	207/8380	3.70	7.62e-41	9.67e-39	207
GO:0030098	GO:0030098	lymphocyte differentiation	114/1216	217/8380	3.62	8.92e-41	1.09e-38	217
GO:0032943	GO:0032943	mononuclear cell proliferation	103/1216	183/8380	3.88	1.74e-40	2.07e-38	183
GO:0046651	GO:0046651	lymphocyte proliferation	102/1216	181/8380	3.88	3.67e-40	4.21e-38	181
GO:0031347	GO:0031347	regulation of defense response	174/1216	445/8380	2.69	1.07e-39	1.19e-37	445
GO:0050870	GO:0050870	positive regulation of T cell activation	90/1216	147/8380	4.22	1.48e-39	1.59e-37	147
GO:0070661	GO:0070661	leukocyte proliferation	106/1216	196/8380	3.73	1.79e-39	1.88e-37	196
GO:0030097	GO:0030097	hemopoiesis	181/1216	477/8380	2.61	3.20e-39	3.25e-37	477
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	96/1216	172/8380	3.85	2.42e-37	2.39e-35	172
GO:0001819	GO:0001819	positive regulation of cytokine production	126/1216	274/8380	3.17	3.51e-37	3.38e-35	274
GO:0002697	GO:0002697	regulation of immune effector process	118/1216	248/8380	3.28	1.22e-36	1.14e-34	248
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	129/1216	291/8380	3.05	5.44e-36	4.96e-34	291
GO:0043299	GO:0043299	leukocyte degranulation	126/1216	283/8380	3.07	2.16e-35	1.92e-33	283
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	98/1216	186/8380	3.63	3.03e-35	2.63e-33	186
GO:0070663	GO:0070663	regulation of leukocyte proliferation	90/1216	162/8380	3.83	7.88e-35	6.67e-33	162
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	88/1216	156/8380	3.89	9.04e-35	7.36e-33	156
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	127/1216	290/8380	3.02	9.11e-35	7.36e-33	290
GO:0002449	GO:0002449	lymphocyte mediated immunity	89/1216	161/8380	3.81	3.20e-34	2.53e-32	161
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	87/1216	155/8380	3.87	3.72e-34	2.88e-32	155
GO:0050900	GO:0050900	leukocyte migration	130/1216	319/8380	2.81	1.08e-31	8.15e-30	319
GO:0036230	GO:0036230	granulocyte activation	115/1216	263/8380	3.01	2.00e-31	1.48e-29	263
GO:0042119	GO:0042119	neutrophil activation	113/1216	260/8380	3.00	1.36e-30	9.84e-29	260
GO:0022407	GO:0022407	regulation of cell-cell adhesion	117/1216	276/8380	2.92	1.94e-30	1.38e-28	276
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	76/1216	134/8380	3.91	2.36e-30	1.64e-28	134
GO:0042113	GO:0042113	B cell activation	74/1216	131/8380	3.89	2.01e-29	1.37e-27	131
GO:0002283	GO:0002283	neutrophil activation involved in immune response	109/1216	252/8380	2.98	2.63e-29	1.77e-27	252
GO:0002683	GO:0002683	negative regulation of immune system process	117/1216	284/8380	2.84	4.60e-29	3.03e-27	284
GO:0030217	GO:0030217	T cell differentiation	83/1216	162/8380	3.53	7.99e-29	5.17e-27	162
GO:0045785	GO:0045785	positive regulation of cell adhesion	117/1216	287/8380	2.81	1.45e-28	9.19e-27	287
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	65/1216	107/8380	4.19	1.61e-28	1.01e-26	107
GO:0043312	GO:0043312	neutrophil degranulation	107/1216	249/8380	2.96	1.75e-28	1.07e-26	249
GO:0002699	GO:0002699	positive regulation of immune effector process	76/1216	141/8380	3.71	2.29e-28	1.38e-26	141
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	64/1216	105/8380	4.20	3.24e-28	1.92e-26	105
GO:0002446	GO:0002446	neutrophil mediated immunity	108/1216	256/8380	2.91	6.47e-28	3.77e-26	256
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	63/1216	104/8380	4.17	1.42e-27	8.15e-26	104
GO:0042098	GO:0042098	T cell proliferation	71/1216	129/8380	3.79	2.58e-27	1.45e-25	129
GO:0046631	GO:0046631	alpha-beta T cell activation	60/1216	97/8380	4.26	5.13e-27	2.85e-25	97
GO:0050852	GO:0050852	T cell receptor signaling pathway	56/1216	87/8380	4.44	1.41e-26	7.70e-25	87
GO:0034341	GO:0034341	response to interferon-gamma	72/1216	135/8380	3.68	1.53e-26	8.22e-25	135
GO:0045055	GO:0045055	regulated exocytosis	154/1216	460/8380	2.31	3.05e-26	1.62e-24	460
GO:0050727	GO:0050727	regulation of inflammatory response	103/1216	251/8380	2.83	1.74e-25	9.10e-24	251
GO:0030155	GO:0030155	regulation of cell adhesion	152/1216	458/8380	2.29	1.90e-25	9.81e-24	458
GO:0031349	GO:0031349	positive regulation of defense response	109/1216	275/8380	2.73	1.99e-25	1.01e-23	275
GO:0042102	GO:0042102	positive regulation of T cell proliferation	51/1216	78/8380	4.51	8.82e-25	4.42e-23	78
GO:0050853	GO:0050853	B cell receptor signaling pathway	35/1216	40/8380	6.03	9.38e-25	4.63e-23	40
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	58/1216	98/8380	4.08	9.92e-25	4.83e-23	98
GO:0006909	GO:0006909	phagocytosis	72/1216	143/8380	3.47	1.57e-24	7.56e-23	143
GO:1902105	GO:1902105	regulation of leukocyte differentiation	82/1216	179/8380	3.16	2.92e-24	1.39e-22	179
GO:0009617	GO:0009617	response to bacterium	135/1216	395/8380	2.36	5.59e-24	2.61e-22	395
GO:0045088	GO:0045088	regulation of innate immune response	91/1216	215/8380	2.92	9.34e-24	4.31e-22	215
GO:0042129	GO:0042129	regulation of T cell proliferation	62/1216	114/8380	3.75	1.30e-23	5.94e-22	114
GO:0071346	GO:0071346	cellular response to interferon-gamma	64/1216	121/8380	3.65	1.90e-23	8.55e-22	121
GO:0002819	GO:0002819	regulation of adaptive immune response	59/1216	107/8380	3.80	6.16e-23	2.74e-21	107
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	55/1216	97/8380	3.91	2.97e-22	1.30e-20	97
GO:0002695	GO:0002695	negative regulation of leukocyte activation	59/1216	111/8380	3.66	7.56e-22	3.28e-20	111
GO:1903706	GO:1903706	regulation of hemopoiesis	97/1216	251/8380	2.66	9.41e-22	4.03e-20	251
GO:0032609	GO:0032609	interferon-gamma production	51/1216	87/8380	4.04	1.27e-21	5.38e-20	87
GO:0050866	GO:0050866	negative regulation of cell activation	63/1216	128/8380	3.39	6.28e-21	2.63e-19	128
GO:0050663	GO:0050663	cytokine secretion	69/1216	149/8380	3.19	6.59e-21	2.73e-19	149
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	50/1216	87/8380	3.96	1.08e-20	4.40e-19	87
GO:0030595	GO:0030595	leukocyte chemotaxis	75/1216	172/8380	3.00	1.11e-20	4.48e-19	172
GO:0002237	GO:0002237	response to molecule of bacterial origin	88/1216	224/8380	2.71	2.24e-20	8.97e-19	224
GO:0060326	GO:0060326	cell chemotaxis	88/1216	225/8380	2.70	3.18e-20	1.26e-18	225
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	42/1216	66/8380	4.39	5.99e-20	2.34e-18	66
GO:0097529	GO:0097529	myeloid leukocyte migration	70/1216	158/8380	3.05	7.56e-20	2.92e-18	158
GO:0032103	GO:0032103	positive regulation of response to external stimulus	83/1216	208/8380	2.75	8.85e-20	3.39e-18	208
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	53/1216	100/8380	3.65	1.13e-19	4.29e-18	100
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	42/1216	67/8380	4.32	1.38e-19	5.18e-18	67
GO:0046632	GO:0046632	alpha-beta T cell differentiation	43/1216	71/8380	4.17	3.45e-19	1.28e-17	71
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	56/1216	112/8380	3.45	3.80e-19	1.39e-17	112
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	50/1216	93/8380	3.71	5.54e-19	2.01e-17	93
GO:0006897	GO:0006897	endocytosis	125/1216	396/8380	2.18	6.56e-19	2.35e-17	396
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	46/1216	81/8380	3.91	7.54e-19	2.68e-17	81
GO:0032649	GO:0032649	regulation of interferon-gamma production	45/1216	78/8380	3.98	7.70e-19	2.71e-17	78
GO:0002286	GO:0002286	T cell activation involved in immune response	39/1216	61/8380	4.41	1.02e-18	3.55e-17	61
GO:0050707	GO:0050707	regulation of cytokine secretion	60/1216	128/8380	3.23	1.18e-18	4.07e-17	128
GO:0045089	GO:0045089	positive regulation of innate immune response	75/1216	184/8380	2.81	1.32e-18	4.52e-17	184
GO:0002821	GO:0002821	positive regulation of adaptive immune response	42/1216	70/8380	4.13	1.48e-18	5.03e-17	70
GO:0050864	GO:0050864	regulation of B cell activation	43/1216	73/8380	4.06	1.55e-18	5.20e-17	73
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	31/1216	41/8380	5.21	1.89e-18	6.28e-17	41
GO:0032496	GO:0032496	response to lipopolysaccharide	82/1216	214/8380	2.64	2.87e-18	9.44e-17	214
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	40/1216	66/8380	4.18	5.94e-18	1.92e-16	66
GO:0034612	GO:0034612	response to tumor necrosis factor	68/1216	161/8380	2.91	5.94e-18	1.92e-16	161
GO:0019882	GO:0019882	antigen processing and presentation	49/1216	94/8380	3.59	6.98e-18	2.23e-16	94
GO:0072676	GO:0072676	lymphocyte migration	46/1216	85/8380	3.73	1.03e-17	3.26e-16	85
GO:0042107	GO:0042107	cytokine metabolic process	42/1216	73/8380	3.96	1.32e-17	4.14e-16	73
GO:0045580	GO:0045580	regulation of T cell differentiation	48/1216	92/8380	3.60	1.45e-17	4.53e-16	92
GO:0042100	GO:0042100	B cell proliferation	36/1216	56/8380	4.43	1.72e-17	5.32e-16	56
GO:0071216	GO:0071216	cellular response to biotic stimulus	61/1216	138/8380	3.05	2.19e-17	6.71e-16	138
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	59/1216	131/8380	3.10	2.50e-17	7.58e-16	131
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	41/1216	71/8380	3.98	2.68e-17	8.09e-16	71
GO:0001818	GO:0001818	negative regulation of cytokine production	69/1216	169/8380	2.81	2.98e-17	8.89e-16	169
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	64/1216	150/8380	2.94	3.11e-17	9.23e-16	150
GO:0042089	GO:0042089	cytokine biosynthetic process	41/1216	72/8380	3.92	5.37e-17	1.58e-15	72
GO:0097530	GO:0097530	granulocyte migration	52/1216	109/8380	3.29	9.65e-17	2.81e-15	109
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	48/1216	96/8380	3.45	1.37e-16	3.97e-15	96
GO:1990868	GO:1990868	response to chemokine	44/1216	83/8380	3.65	1.50e-16	4.28e-15	83
GO:1990869	GO:1990869	cellular response to chemokine	44/1216	83/8380	3.65	1.50e-16	4.28e-15	83
GO:0001906	GO:0001906	cell killing	52/1216	110/8380	3.26	1.58e-16	4.45e-15	110
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	42/1216	77/8380	3.76	1.88e-16	5.27e-15	77
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	48/1216	97/8380	3.41	2.34e-16	6.46e-15	97
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	48/1216	97/8380	3.41	2.34e-16	6.46e-15	97
GO:0098542	GO:0098542	defense response to other organism	89/1216	259/8380	2.37	3.16e-16	8.64e-15	259
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	38/1216	66/8380	3.97	4.57e-16	1.24e-14	66
GO:0098657	GO:0098657	import into cell	137/1216	485/8380	1.95	4.88e-16	1.31e-14	485
GO:0050729	GO:0050729	positive regulation of inflammatory response	48/1216	99/8380	3.34	6.63e-16	1.77e-14	99
GO:0002685	GO:0002685	regulation of leukocyte migration	59/1216	139/8380	2.93	7.43e-16	1.97e-14	139
GO:0031295	GO:0031295	T cell costimulation	28/1216	39/8380	4.95	8.51e-16	2.24e-14	39
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	36/1216	61/8380	4.07	9.20e-16	2.40e-14	61
GO:0038093	GO:0038093	Fc receptor signaling pathway	37/1216	64/8380	3.98	9.31e-16	2.42e-14	64
GO:0006968	GO:0006968	cellular defense response	31/1216	47/8380	4.55	1.04e-15	2.69e-14	47
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	55/1216	126/8380	3.01	1.66e-15	4.26e-14	126
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	30/1216	45/8380	4.59	1.96e-15	4.97e-14	45
GO:0031294	GO:0031294	lymphocyte costimulation	28/1216	40/8380	4.82	2.45e-15	6.17e-14	40
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	32/1216	51/8380	4.32	3.06e-15	7.67e-14	51
GO:0071674	GO:0071674	mononuclear cell migration	38/1216	69/8380	3.80	3.42e-15	8.50e-14	69
GO:1990266	GO:1990266	neutrophil migration	45/1216	93/8380	3.33	5.98e-15	1.48e-13	93
GO:0031341	GO:0031341	regulation of cell killing	38/1216	70/8380	3.74	6.45e-15	1.58e-13	70
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	36/1216	64/8380	3.88	7.50e-15	1.83e-13	64
GO:0071621	GO:0071621	granulocyte chemotaxis	46/1216	99/8380	3.20	2.04e-14	4.94e-13	99
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	44/1216	92/8380	3.30	2.05e-14	4.94e-13	92
GO:0002440	GO:0002440	production of molecular mediator of immune response	50/1216	114/8380	3.02	2.60e-14	6.19e-13	114
GO:1903708	GO:1903708	positive regulation of hemopoiesis	51/1216	118/8380	2.98	2.94e-14	6.96e-13	118
GO:0045582	GO:0045582	positive regulation of T cell differentiation	33/1216	57/8380	3.99	3.22e-14	7.57e-13	57
GO:0032640	GO:0032640	tumor necrosis factor production	44/1216	93/8380	3.26	3.36e-14	7.87e-13	93
GO:0002886	GO:0002886	regulation of myeloid leukocyte mediated immunity	25/1216	35/8380	4.92	3.75e-14	8.71e-13	35
GO:0002218	GO:0002218	activation of innate immune response	56/1216	138/8380	2.80	4.26e-14	9.85e-13	138
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	31/1216	52/8380	4.11	6.37e-14	1.46e-12	52
GO:0019724	GO:0019724	B cell mediated immunity	36/1216	68/8380	3.65	9.40e-14	2.14e-12	68
GO:0030888	GO:0030888	regulation of B cell proliferation	28/1216	44/8380	4.39	1.01e-13	2.29e-12	44
GO:0072678	GO:0072678	T cell migration	29/1216	47/8380	4.25	1.17e-13	2.64e-12	47
GO:0002758	GO:0002758	innate immune response-activating signal transduction	54/1216	133/8380	2.80	1.19e-13	2.67e-12	133
GO:0002456	GO:0002456	T cell mediated immunity	38/1216	75/8380	3.49	1.22e-13	2.71e-12	75
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	26/1216	39/8380	4.59	1.52e-13	3.35e-12	39
GO:0030593	GO:0030593	neutrophil chemotaxis	41/1216	86/8380	3.29	1.84e-13	4.04e-12	86
GO:0002292	GO:0002292	T cell differentiation involved in immune response	28/1216	45/8380	4.29	2.31e-13	5.04e-12	45
GO:0002573	GO:0002573	myeloid leukocyte differentiation	53/1216	131/8380	2.79	2.40e-13	5.19e-12	131
GO:0050868	GO:0050868	negative regulation of T cell activation	36/1216	70/8380	3.54	3.01e-13	6.49e-12	70
GO:0042088	GO:0042088	T-helper 1 type immune response	23/1216	32/8380	4.95	3.27e-13	7.00e-12	32
GO:0016064	GO:0016064	immunoglobulin mediated immune response	35/1216	67/8380	3.60	3.52e-13	7.45e-12	67
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	35/1216	67/8380	3.60	3.52e-13	7.45e-12	67
GO:0050871	GO:0050871	positive regulation of B cell activation	28/1216	46/8380	4.19	5.09e-13	1.07e-11	46
GO:0048247	GO:0048247	lymphocyte chemotaxis	30/1216	52/8380	3.98	5.46e-13	1.14e-11	52
GO:0051345	GO:0051345	positive regulation of hydrolase activity	109/1216	386/8380	1.95	6.49e-13	1.35e-11	386
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	33/1216	62/8380	3.67	8.37e-13	1.73e-11	62
GO:0071887	GO:0071887	leukocyte apoptotic process	35/1216	69/8380	3.50	1.09e-12	2.25e-11	69
GO:0006935	GO:0006935	chemotaxis	124/1216	466/8380	1.83	1.54e-12	3.14e-11	466
GO:0042330	GO:0042330	taxis	124/1216	467/8380	1.83	1.81e-12	3.67e-11	467
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	26/1216	42/8380	4.27	2.00e-12	4.04e-11	42
GO:0002228	GO:0002228	natural killer cell mediated immunity	27/1216	45/8380	4.13	2.18e-12	4.36e-11	45
GO:0032623	GO:0032623	interleukin-2 production	27/1216	45/8380	4.13	2.18e-12	4.36e-11	45
GO:0043300	GO:0043300	regulation of leukocyte degranulation	21/1216	29/8380	4.99	2.85e-12	5.65e-11	29
GO:0002687	GO:0002687	positive regulation of leukocyte migration	41/1216	92/8380	3.07	3.00e-12	5.92e-11	92
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	24/1216	37/8380	4.47	3.29e-12	6.46e-11	37
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	37/1216	78/8380	3.27	3.41e-12	6.65e-11	78
GO:0050715	GO:0050715	positive regulation of cytokine secretion	40/1216	89/8380	3.10	3.96e-12	7.70e-11	89
GO:0002548	GO:0002548	monocyte chemotaxis	30/1216	55/8380	3.76	4.00e-12	7.73e-11	55
GO:0002377	GO:0002377	immunoglobulin production	28/1216	49/8380	3.94	4.53e-12	8.71e-11	49
GO:0046633	GO:0046633	alpha-beta T cell proliferation	20/1216	27/8380	5.10	4.77e-12	9.13e-11	27
GO:0044419	GO:0044419	interspecies interaction between organisms	93/1216	319/8380	2.01	5.01e-12	9.53e-11	319
GO:0030183	GO:0030183	B cell differentiation	32/1216	62/8380	3.56	5.61e-12	1.06e-10	62
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	32/1216	62/8380	3.56	5.61e-12	1.06e-10	62
GO:0009615	GO:0009615	response to virus	58/1216	161/8380	2.48	5.95e-12	1.11e-10	161
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	74/1216	231/8380	2.21	5.97e-12	1.11e-10	231
GO:0032653	GO:0032653	regulation of interleukin-10 production	23/1216	35/8380	4.53	6.26e-12	1.16e-10	35
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	38/1216	83/8380	3.16	6.82e-12	1.26e-10	83
GO:0030099	GO:0030099	myeloid cell differentiation	72/1216	223/8380	2.23	7.64e-12	1.40e-10	223
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	19/1216	25/8380	5.24	7.71e-12	1.41e-10	25
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	25/1216	41/8380	4.20	8.71e-12	1.57e-10	41
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	25/1216	41/8380	4.20	8.71e-12	1.57e-10	41
GO:0032655	GO:0032655	regulation of interleukin-12 production	22/1216	33/8380	4.59	1.18e-11	2.11e-10	33
GO:0045058	GO:0045058	T cell selection	22/1216	33/8380	4.59	1.18e-11	2.11e-10	33
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	18/1216	23/8380	5.39	1.19e-11	2.11e-10	23
GO:0032613	GO:0032613	interleukin-10 production	23/1216	36/8380	4.40	1.50e-11	2.65e-10	36
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	29/1216	54/8380	3.70	1.54e-11	2.71e-10	54
GO:0016032	GO:0016032	viral process	79/1216	259/8380	2.10	1.85e-11	3.24e-10	259
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	25/1216	42/8380	4.10	1.86e-11	3.24e-10	42
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	19/1216	26/8380	5.04	2.48e-11	4.29e-10	26
GO:0032615	GO:0032615	interleukin-12 production	22/1216	34/8380	4.46	2.89e-11	4.98e-10	34
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	34/1216	72/8380	3.25	3.03e-11	5.20e-10	72
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	37/1216	83/8380	3.07	3.44e-11	5.89e-10	83
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	27/1216	49/8380	3.80	3.51e-11	5.94e-10	49
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	27/1216	49/8380	3.80	3.51e-11	5.94e-10	49
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	24/1216	40/8380	4.13	3.73e-11	6.29e-10	40
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	33/1216	69/8380	3.30	3.84e-11	6.45e-10	69
GO:0006959	GO:0006959	humoral immune response	61/1216	181/8380	2.32	4.33e-11	7.22e-10	181
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	21/1216	32/8380	4.52	5.52e-11	9.16e-10	32
GO:0001776	GO:0001776	leukocyte homeostasis	30/1216	60/8380	3.45	7.33e-11	1.21e-09	60
GO:0032663	GO:0032663	regulation of interleukin-2 production	23/1216	38/8380	4.17	7.47e-11	1.22e-09	38
GO:0038094	GO:0038094	Fc-gamma receptor signaling pathway	23/1216	38/8380	4.17	7.47e-11	1.22e-09	38
GO:0044403	GO:0044403	symbiont process	84/1216	290/8380	2.00	8.17e-11	1.33e-09	290
GO:0032635	GO:0032635	interleukin-6 production	37/1216	86/8380	2.96	1.23e-10	1.99e-09	86
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	15/1216	18/8380	5.74	1.31e-10	2.11e-09	18
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	29/1216	58/8380	3.45	1.52e-10	2.45e-09	58
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	14/1216	16/8380	6.03	1.55e-10	2.47e-09	16
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	14/1216	16/8380	6.03	1.55e-10	2.47e-09	16
GO:0031348	GO:0031348	negative regulation of defense response	45/1216	118/8380	2.63	1.66e-10	2.63e-09	118
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	30/1216	62/8380	3.33	2.08e-10	3.29e-09	62
GO:0031343	GO:0031343	positive regulation of cell killing	27/1216	52/8380	3.58	2.17e-10	3.41e-09	52
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	20/1216	31/8380	4.45	2.54e-10	3.97e-09	31
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	25/1216	46/8380	3.75	2.81e-10	4.37e-09	46
GO:0045123	GO:0045123	cellular extravasation	25/1216	46/8380	3.75	2.81e-10	4.37e-09	46
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	34/1216	77/8380	3.04	2.97e-10	4.59e-09	77
GO:0030003	GO:0030003	cellular cation homeostasis	106/1216	408/8380	1.79	3.37e-10	5.18e-09	408
GO:0045066	GO:0045066	regulatory T cell differentiation	16/1216	21/8380	5.25	3.50e-10	5.36e-09	21
GO:0019722	GO:0019722	calcium-mediated signaling	52/1216	150/8380	2.39	3.80e-10	5.79e-09	150
GO:0006874	GO:0006874	cellular calcium ion homeostasis	87/1216	313/8380	1.92	3.86e-10	5.86e-09	313
GO:0050777	GO:0050777	negative regulation of immune response	37/1216	89/8380	2.86	4.05e-10	6.12e-09	89
GO:0048872	GO:0048872	homeostasis of number of cells	50/1216	142/8380	2.43	4.44e-10	6.69e-09	142
GO:0002709	GO:0002709	regulation of T cell mediated immunity	26/1216	50/8380	3.58	4.50e-10	6.75e-09	50
GO:0055074	GO:0055074	calcium ion homeostasis	89/1216	324/8380	1.89	4.67e-10	6.98e-09	324
GO:0042116	GO:0042116	macrophage activation	28/1216	57/8380	3.39	5.37e-10	7.93e-09	57
GO:0002507	GO:0002507	tolerance induction	15/1216	19/8380	5.44	5.38e-10	7.93e-09	19
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	15/1216	19/8380	5.44	5.38e-10	7.93e-09	19
GO:0030335	GO:0030335	positive regulation of cell migration	88/1216	320/8380	1.90	5.53e-10	8.12e-09	320
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	11/1216	11/8380	6.89	5.78e-10	8.45e-09	11
GO:0002224	GO:0002224	toll-like receptor signaling pathway	33/1216	75/8380	3.03	6.08e-10	8.87e-09	75
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	21/1216	35/8380	4.13	6.39e-10	9.28e-09	35
GO:0072507	GO:0072507	divalent inorganic cation homeostasis	94/1216	351/8380	1.85	6.50e-10	9.38e-09	351
GO:0042093	GO:0042093	T-helper cell differentiation	22/1216	38/8380	3.99	6.52e-10	9.38e-09	38
GO:0072503	GO:0072503	cellular divalent inorganic cation homeostasis	91/1216	336/8380	1.87	6.59e-10	9.45e-09	336
GO:0002698	GO:0002698	negative regulation of immune effector process	31/1216	68/8380	3.14	6.85e-10	9.78e-09	68
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	29/1216	61/8380	3.28	7.10e-10	1.01e-08	61
GO:0030100	GO:0030100	regulation of endocytosis	50/1216	144/8380	2.39	7.78e-10	1.10e-08	144
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	75/1216	259/8380	2.00	8.86e-10	1.25e-08	259
GO:0009306	GO:0009306	protein secretion	94/1216	353/8380	1.84	8.99e-10	1.26e-08	353
GO:0032675	GO:0032675	regulation of interleukin-6 production	34/1216	80/8380	2.93	1.03e-09	1.44e-08	80
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	46/1216	128/8380	2.48	1.04e-09	1.44e-08	128
GO:0040017	GO:0040017	positive regulation of locomotion	93/1216	349/8380	1.84	1.07e-09	1.48e-08	349
GO:0030101	GO:0030101	natural killer cell activation	24/1216	45/8380	3.68	1.08e-09	1.49e-08	45
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	16/1216	22/8380	5.01	1.11e-09	1.52e-08	22
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	16/1216	22/8380	5.01	1.11e-09	1.52e-08	22
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	16/1216	22/8380	5.01	1.11e-09	1.52e-08	22
GO:0050764	GO:0050764	regulation of phagocytosis	27/1216	55/8380	3.38	1.12e-09	1.52e-08	55
GO:0002790	GO:0002790	peptide secretion	99/1216	380/8380	1.80	1.14e-09	1.55e-08	380
GO:0032633	GO:0032633	interleukin-4 production	19/1216	30/8380	4.36	1.15e-09	1.55e-08	30
GO:0097028	GO:0097028	dendritic cell differentiation	19/1216	30/8380	4.36	1.15e-09	1.55e-08	30
GO:0045807	GO:0045807	positive regulation of endocytosis	36/1216	88/8380	2.82	1.19e-09	1.60e-08	88
GO:0002526	GO:0002526	acute inflammatory response	43/1216	116/8380	2.55	1.20e-09	1.61e-08	116
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	38/1216	96/8380	2.73	1.28e-09	1.70e-08	96
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	20/1216	33/8380	4.18	1.28e-09	1.70e-08	33
GO:0002431	GO:0002431	Fc receptor mediated stimulatory signaling pathway	22/1216	39/8380	3.89	1.29e-09	1.71e-08	39
GO:0006873	GO:0006873	cellular ion homeostasis	106/1216	418/8380	1.75	1.49e-09	1.97e-08	418
GO:0043547	GO:0043547	positive regulation of GTPase activity	63/1216	205/8380	2.12	1.55e-09	2.03e-08	205
GO:0032673	GO:0032673	regulation of interleukin-4 production	17/1216	25/8380	4.69	1.72e-09	2.25e-08	25
GO:0006875	GO:0006875	cellular metal ion homeostasis	98/1216	378/8380	1.79	1.85e-09	2.41e-08	378
GO:0001773	GO:0001773	myeloid dendritic cell activation	15/1216	20/8380	5.17	1.86e-09	2.41e-08	20
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	15/1216	20/8380	5.17	1.86e-09	2.41e-08	20
GO:0002673	GO:0002673	regulation of acute inflammatory response	32/1216	74/8380	2.98	1.89e-09	2.44e-08	74
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	24/1216	46/8380	3.60	1.94e-09	2.49e-08	46
GO:2000147	GO:2000147	positive regulation of cell motility	89/1216	333/8380	1.84	2.12e-09	2.71e-08	333
GO:0002702	GO:0002702	positive regulation of production of molecular mediator of immune response	26/1216	53/8380	3.38	2.32e-09	2.96e-08	53
GO:0030316	GO:0030316	osteoclast differentiation	28/1216	60/8380	3.22	2.38e-09	3.03e-08	60
GO:0045453	GO:0045453	bone resorption	22/1216	40/8380	3.79	2.48e-09	3.14e-08	40
GO:0070555	GO:0070555	response to interleukin-1	38/1216	98/8380	2.67	2.55e-09	3.21e-08	98
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	21/1216	37/8380	3.91	2.65e-09	3.33e-08	37
GO:0043368	GO:0043368	positive T cell selection	16/1216	23/8380	4.79	3.16e-09	3.95e-08	23
GO:0002504	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	24/1216	47/8380	3.52	3.43e-09	4.27e-08	47
GO:0002260	GO:0002260	lymphocyte homeostasis	23/1216	44/8380	3.60	4.03e-09	5.00e-08	44
GO:0050710	GO:0050710	negative regulation of cytokine secretion	23/1216	44/8380	3.60	4.03e-09	5.00e-08	44
GO:0043410	GO:0043410	positive regulation of MAPK cascade	97/1216	379/8380	1.76	4.65e-09	5.74e-08	379
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	21/1216	38/8380	3.81	5.12e-09	6.30e-08	38
GO:0002433	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	20/1216	35/8380	3.94	5.43e-09	6.61e-08	35
GO:0002448	GO:0002448	mast cell mediated immunity	20/1216	35/8380	3.94	5.43e-09	6.61e-08	35
GO:0038096	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	20/1216	35/8380	3.94	5.43e-09	6.61e-08	35
GO:0002637	GO:0002637	regulation of immunoglobulin production	19/1216	32/8380	4.09	5.45e-09	6.62e-08	32
GO:0055080	GO:0055080	cation homeostasis	112/1216	460/8380	1.68	6.23e-09	7.53e-08	460
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	26/1216	55/8380	3.26	6.32e-09	7.62e-08	55
GO:0010942	GO:0010942	positive regulation of cell death	92/1216	356/8380	1.78	7.08e-09	8.51e-08	356
GO:0045576	GO:0045576	mast cell activation	23/1216	45/8380	3.52	7.13e-09	8.53e-08	45
GO:0002791	GO:0002791	regulation of peptide secretion	83/1216	311/8380	1.84	8.14e-09	9.71e-08	311
GO:2000401	GO:2000401	regulation of lymphocyte migration	22/1216	42/8380	3.61	8.38e-09	9.97e-08	42
GO:0032612	GO:0032612	interleukin-1 production	28/1216	63/8380	3.06	9.30e-09	1.10e-07	63
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	33/1216	82/8380	2.77	9.58e-09	1.13e-07	82
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	33/1216	82/8380	2.77	9.58e-09	1.13e-07	82
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	14/1216	19/8380	5.08	9.75e-09	1.14e-07	19
GO:0098771	GO:0098771	inorganic ion homeostasis	113/1216	469/8380	1.66	1.00e-08	1.17e-07	469
GO:1903530	GO:1903530	regulation of secretion by cell	114/1216	475/8380	1.65	1.08e-08	1.26e-07	475
GO:0043303	GO:0043303	mast cell degranulation	19/1216	33/8380	3.97	1.11e-08	1.29e-07	33
GO:0051272	GO:0051272	positive regulation of cellular component movement	89/1216	344/8380	1.78	1.19e-08	1.38e-07	344
GO:0050708	GO:0050708	regulation of protein secretion	78/1216	289/8380	1.86	1.36e-08	1.57e-07	289
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	33/1216	83/8380	2.74	1.37e-08	1.58e-07	83
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	22/1216	43/8380	3.53	1.48e-08	1.70e-07	43
GO:0043068	GO:0043068	positive regulation of programmed cell death	84/1216	320/8380	1.81	1.52e-08	1.74e-07	320
GO:0051208	GO:0051208	sequestering of calcium ion	33/1216	84/8380	2.71	1.95e-08	2.22e-07	84
GO:0032611	GO:0032611	interleukin-1 beta production	25/1216	54/8380	3.19	2.11e-08	2.39e-07	54
GO:0002279	GO:0002279	mast cell activation involved in immune response	19/1216	34/8380	3.85	2.18e-08	2.46e-07	34
GO:0010324	GO:0010324	membrane invagination	19/1216	34/8380	3.85	2.18e-08	2.46e-07	34
GO:0055065	GO:0055065	metal ion homeostasis	104/1216	427/8380	1.68	2.21e-08	2.48e-07	427
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	17/1216	28/8380	4.18	2.21e-08	2.48e-07	28
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	39/1216	109/8380	2.47	2.24e-08	2.50e-07	109
GO:0006911	GO:0006911	phagocytosis, engulfment	18/1216	31/8380	4.00	2.27e-08	2.52e-07	31
GO:0030890	GO:0030890	positive regulation of B cell proliferation	18/1216	31/8380	4.00	2.27e-08	2.52e-07	31
GO:0051090	GO:0051090	regulation of DNA-binding transcription factor activity	61/1216	209/8380	2.01	2.48e-08	2.75e-07	209
GO:0032660	GO:0032660	regulation of interleukin-17 production	14/1216	20/8380	4.82	2.82e-08	3.09e-07	20
GO:0043304	GO:0043304	regulation of mast cell degranulation	14/1216	20/8380	4.82	2.82e-08	3.09e-07	20
GO:0050869	GO:0050869	negative regulation of B cell activation	14/1216	20/8380	4.82	2.82e-08	3.09e-07	20
GO:0048771	GO:0048771	tissue remodeling	39/1216	110/8380	2.44	2.99e-08	3.27e-07	110
GO:0050766	GO:0050766	positive regulation of phagocytosis	21/1216	41/8380	3.53	3.09e-08	3.36e-07	41
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	21/1216	41/8380	3.53	3.09e-08	3.36e-07	41
GO:0002367	GO:0002367	cytokine production involved in immune response	28/1216	66/8380	2.92	3.24e-08	3.52e-07	66
GO:0002312	GO:0002312	B cell activation involved in immune response	20/1216	38/8380	3.63	3.63e-08	3.92e-07	38
GO:0060627	GO:0060627	regulation of vesicle-mediated transport	76/1216	285/8380	1.84	3.68e-08	3.95e-07	285
GO:0051607	GO:0051607	defense response to virus	40/1216	115/8380	2.40	3.68e-08	3.95e-07	115
GO:0032620	GO:0032620	interleukin-17 production	15/1216	23/8380	4.49	3.82e-08	4.08e-07	23
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	15/1216	23/8380	4.49	3.82e-08	4.08e-07	23
GO:0032418	GO:0032418	lysosome localization	19/1216	35/8380	3.74	4.12e-08	4.37e-07	35
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	19/1216	35/8380	3.74	4.12e-08	4.37e-07	35
GO:0033003	GO:0033003	regulation of mast cell activation	17/1216	29/8380	4.04	4.63e-08	4.90e-07	29
GO:0042742	GO:0042742	defense response to bacterium	47/1216	147/8380	2.20	4.92e-08	5.19e-07	147
GO:0001913	GO:0001913	T cell mediated cytotoxicity	21/1216	42/8380	3.45	5.34e-08	5.62e-07	42
GO:0043065	GO:0043065	positive regulation of apoptotic process	82/1216	318/8380	1.78	5.36e-08	5.62e-07	318
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	20/1216	39/8380	3.53	6.43e-08	6.73e-07	39
GO:0050921	GO:0050921	positive regulation of chemotaxis	35/1216	96/8380	2.51	6.84e-08	7.13e-07	96
GO:0043087	GO:0043087	regulation of GTPase activity	67/1216	244/8380	1.89	7.18e-08	7.47e-07	244
GO:0033006	GO:0033006	regulation of mast cell activation involved in immune response	14/1216	21/8380	4.59	7.32e-08	7.59e-07	21
GO:0099024	GO:0099024	plasma membrane invagination	18/1216	33/8380	3.76	8.54e-08	8.83e-07	33
GO:0002544	GO:0002544	chronic inflammatory response	12/1216	16/8380	5.17	8.57e-08	8.83e-07	16
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	15/1216	24/8380	4.31	8.83e-08	9.04e-07	24
GO:0045730	GO:0045730	respiratory burst	15/1216	24/8380	4.31	8.83e-08	9.04e-07	24
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	17/1216	30/8380	3.91	9.25e-08	9.45e-07	30
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	16/1216	27/8380	4.08	9.42e-08	9.60e-07	27
GO:0050714	GO:0050714	positive regulation of protein secretion	50/1216	164/8380	2.10	1.02e-07	1.04e-06	164
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	24/1216	54/8380	3.06	1.07e-07	1.08e-06	54
GO:0032652	GO:0032652	regulation of interleukin-1 production	24/1216	54/8380	3.06	1.07e-07	1.08e-06	54
GO:0050920	GO:0050920	regulation of chemotaxis	48/1216	155/8380	2.13	1.08e-07	1.09e-06	155
GO:0002755	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/1216	19/8380	4.72	1.38e-07	1.38e-06	19
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	13/1216	19/8380	4.72	1.38e-07	1.38e-06	19
GO:0070374	GO:0070374	positive regulation of ERK1 and ERK2 cascade	53/1216	180/8380	2.03	1.51e-07	1.51e-06	180
GO:0002920	GO:0002920	regulation of humoral immune response	24/1216	55/8380	3.01	1.64e-07	1.63e-06	55
GO:0018108	GO:0018108	peptidyl-tyrosine phosphorylation	67/1216	249/8380	1.85	1.67e-07	1.65e-06	249
GO:0018212	GO:0018212	peptidyl-tyrosine modification	67/1216	249/8380	1.85	1.67e-07	1.65e-06	249
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	14/1216	22/8380	4.39	1.74e-07	1.72e-06	22
GO:0032715	GO:0032715	negative regulation of interleukin-6 production	16/1216	28/8380	3.94	1.90e-07	1.87e-06	28
GO:0070371	GO:0070371	ERK1 and ERK2 cascade	65/1216	240/8380	1.87	1.97e-07	1.93e-06	240
GO:0071347	GO:0071347	cellular response to interleukin-1	31/1216	83/8380	2.57	2.04e-07	2.00e-06	83
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	29/1216	75/8380	2.66	2.11e-07	2.07e-06	75
GO:0019058	GO:0019058	viral life cycle	43/1216	136/8380	2.18	2.60e-07	2.53e-06	136
GO:0032602	GO:0032602	chemokine production	25/1216	60/8380	2.87	2.70e-07	2.62e-06	60
GO:0070372	GO:0070372	regulation of ERK1 and ERK2 cascade	62/1216	227/8380	1.88	2.73e-07	2.65e-06	227
GO:0050702	GO:0050702	interleukin-1 beta secretion	18/1216	35/8380	3.54	2.80e-07	2.70e-06	35
GO:0002793	GO:0002793	positive regulation of peptide secretion	52/1216	179/8380	2.00	3.17e-07	3.05e-06	179
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	33/1216	93/8380	2.45	3.37e-07	3.24e-06	93
GO:0002714	GO:0002714	positive regulation of B cell mediated immunity	13/1216	20/8380	4.48	3.41e-07	3.25e-06	20
GO:0002891	GO:0002891	positive regulation of immunoglobulin mediated immune response	13/1216	20/8380	4.48	3.41e-07	3.25e-06	20
GO:0010818	GO:0010818	T cell chemotaxis	13/1216	20/8380	4.48	3.41e-07	3.25e-06	20
GO:0002712	GO:0002712	regulation of B cell mediated immunity	16/1216	29/8380	3.80	3.68e-07	3.49e-06	29
GO:0002889	GO:0002889	regulation of immunoglobulin mediated immune response	16/1216	29/8380	3.80	3.68e-07	3.49e-06	29
GO:0032651	GO:0032651	regulation of interleukin-1 beta production	21/1216	46/8380	3.15	3.84e-07	3.62e-06	46
GO:0070227	GO:0070227	lymphocyte apoptotic process	21/1216	46/8380	3.15	3.84e-07	3.62e-06	46
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	14/1216	23/8380	4.19	3.86e-07	3.63e-06	23
GO:0002532	GO:0002532	production of molecular mediator involved in inflammatory response	19/1216	39/8380	3.36	3.91e-07	3.67e-06	39
GO:0045637	GO:0045637	regulation of myeloid cell differentiation	43/1216	138/8380	2.15	4.09e-07	3.83e-06	138
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	26/1216	65/8380	2.76	4.10e-07	3.83e-06	65
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	34/1216	98/8380	2.39	4.14e-07	3.85e-06	98
GO:0043408	GO:0043408	regulation of MAPK cascade	110/1216	484/8380	1.57	4.15e-07	3.85e-06	484
GO:0042533	GO:0042533	tumor necrosis factor biosynthetic process	11/1216	15/8380	5.05	4.48e-07	4.13e-06	15
GO:0042534	GO:0042534	regulation of tumor necrosis factor biosynthetic process	11/1216	15/8380	5.05	4.48e-07	4.13e-06	15
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	11/1216	15/8380	5.05	4.48e-07	4.13e-06	15
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	32/1216	90/8380	2.45	4.81e-07	4.42e-06	90
GO:0030168	GO:0030168	platelet activation	35/1216	103/8380	2.34	4.97e-07	4.56e-06	103
GO:0032637	GO:0032637	interleukin-8 production	20/1216	43/8380	3.21	5.01e-07	4.58e-06	43
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	25/1216	62/8380	2.78	5.71e-07	5.21e-06	62
GO:0045670	GO:0045670	regulation of osteoclast differentiation	19/1216	40/8380	3.27	6.44e-07	5.81e-06	40
GO:0050701	GO:0050701	interleukin-1 secretion	19/1216	40/8380	3.27	6.44e-07	5.81e-06	40
GO:0150076	GO:0150076	neuroinflammatory response	19/1216	40/8380	3.27	6.44e-07	5.81e-06	40
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	19/1216	40/8380	3.27	6.44e-07	5.81e-06	40
GO:0019932	GO:0019932	second-messenger-mediated signaling	79/1216	320/8380	1.70	6.58e-07	5.91e-06	320
GO:1901623	GO:1901623	regulation of lymphocyte chemotaxis	12/1216	18/8380	4.59	6.58e-07	5.91e-06	18
GO:0050728	GO:0050728	negative regulation of inflammatory response	31/1216	87/8380	2.46	6.86e-07	6.14e-06	87
GO:0055082	GO:0055082	cellular chemical homeostasis	112/1216	500/8380	1.54	7.02e-07	6.27e-06	500
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	23/1216	55/8380	2.88	7.49e-07	6.67e-06	55
GO:0048305	GO:0048305	immunoglobulin secretion	10/1216	13/8380	5.30	7.53e-07	6.67e-06	13
GO:0050690	GO:0050690	regulation of defense response to virus by virus	10/1216	13/8380	5.30	7.53e-07	6.67e-06	13
GO:0010469	GO:0010469	regulation of signaling receptor activity	93/1216	396/8380	1.62	7.54e-07	6.67e-06	396
GO:0001774	GO:0001774	microglial cell activation	15/1216	27/8380	3.83	7.63e-07	6.71e-06	27
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	15/1216	27/8380	3.83	7.63e-07	6.71e-06	27
GO:2000406	GO:2000406	positive regulation of T cell migration	13/1216	21/8380	4.27	7.76e-07	6.82e-06	21
GO:0071396	GO:0071396	cellular response to lipid	87/1216	364/8380	1.65	7.91e-07	6.92e-06	364
GO:0032479	GO:0032479	regulation of type I interferon production	20/1216	44/8380	3.13	7.94e-07	6.92e-06	44
GO:0032606	GO:0032606	type I interferon production	20/1216	44/8380	3.13	7.94e-07	6.92e-06	44
GO:0043030	GO:0043030	regulation of macrophage activation	18/1216	37/8380	3.35	8.15e-07	7.09e-06	37
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	37/1216	114/8380	2.24	8.63e-07	7.48e-06	114
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	19/1216	41/8380	3.19	1.04e-06	8.96e-06	41
GO:0070228	GO:0070228	regulation of lymphocyte apoptotic process	19/1216	41/8380	3.19	1.04e-06	8.96e-06	41
GO:0060402	GO:0060402	calcium ion transport into cytosol	35/1216	106/8380	2.28	1.08e-06	9.29e-06	106
GO:0001911	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	9/1216	11/8380	5.64	1.16e-06	9.93e-06	11
GO:0031342	GO:0031342	negative regulation of cell killing	9/1216	11/8380	5.64	1.16e-06	9.93e-06	11
GO:0002577	GO:0002577	regulation of antigen processing and presentation	11/1216	16/8380	4.74	1.25e-06	1.06e-05	16
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	11/1216	16/8380	4.74	1.25e-06	1.06e-05	16
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	11/1216	16/8380	4.74	1.25e-06	1.06e-05	16
GO:0050858	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	11/1216	16/8380	4.74	1.25e-06	1.06e-05	16
GO:0090087	GO:0090087	regulation of peptide transport	92/1216	395/8380	1.61	1.27e-06	1.08e-05	395
GO:0060401	GO:0060401	cytosolic calcium ion transport	35/1216	107/8380	2.25	1.38e-06	1.17e-05	107
GO:0002820	GO:0002820	negative regulation of adaptive immune response	15/1216	28/8380	3.69	1.42e-06	1.20e-05	28
GO:0036336	GO:0036336	dendritic cell migration	12/1216	19/8380	4.35	1.55e-06	1.30e-05	19
GO:0007162	GO:0007162	negative regulation of cell adhesion	49/1216	173/8380	1.95	1.57e-06	1.31e-05	173
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	14/1216	25/8380	3.86	1.58e-06	1.32e-05	25
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	14/1216	25/8380	3.86	1.58e-06	1.32e-05	25
GO:0046849	GO:0046849	bone remodeling	24/1216	61/8380	2.71	1.63e-06	1.35e-05	61
GO:1903532	GO:1903532	positive regulation of secretion by cell	65/1216	254/8380	1.76	1.76e-06	1.47e-05	254
GO:0051047	GO:0051047	positive regulation of secretion	69/1216	275/8380	1.73	1.83e-06	1.52e-05	275
GO:0051223	GO:0051223	regulation of protein transport	87/1216	371/8380	1.62	1.85e-06	1.53e-05	371
GO:0006801	GO:0006801	superoxide metabolic process	20/1216	46/8380	3.00	1.89e-06	1.56e-05	46
GO:0033077	GO:0033077	T cell differentiation in thymus	20/1216	46/8380	3.00	1.89e-06	1.56e-05	46
GO:1903531	GO:1903531	negative regulation of secretion by cell	39/1216	127/8380	2.12	2.11e-06	1.73e-05	127
GO:0002720	GO:0002720	positive regulation of cytokine production involved in immune response	16/1216	32/8380	3.45	2.11e-06	1.73e-05	32
GO:0071675	GO:0071675	regulation of mononuclear cell migration	16/1216	32/8380	3.45	2.11e-06	1.73e-05	32
GO:0030449	GO:0030449	regulation of complement activation	18/1216	39/8380	3.18	2.15e-06	1.75e-05	39
GO:0032677	GO:0032677	regulation of interleukin-8 production	18/1216	39/8380	3.18	2.15e-06	1.75e-05	39
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	40/1216	132/8380	2.09	2.28e-06	1.84e-05	132
GO:0002792	GO:0002792	negative regulation of peptide secretion	30/1216	87/8380	2.38	2.28e-06	1.84e-05	87
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	10/1216	14/8380	4.92	2.29e-06	1.84e-05	14
GO:0002643	GO:0002643	regulation of tolerance induction	10/1216	14/8380	4.92	2.29e-06	1.84e-05	14
GO:0002830	GO:0002830	positive regulation of type 2 immune response	10/1216	14/8380	4.92	2.29e-06	1.84e-05	14
GO:0042095	GO:0042095	interferon-gamma biosynthetic process	10/1216	14/8380	4.92	2.29e-06	1.84e-05	14
GO:0045063	GO:0045063	T-helper 1 cell differentiation	10/1216	14/8380	4.92	2.29e-06	1.84e-05	14
GO:2000404	GO:2000404	regulation of T cell migration	15/1216	29/8380	3.56	2.55e-06	2.04e-05	29
GO:0030162	GO:0030162	regulation of proteolysis	89/1216	385/8380	1.59	2.66e-06	2.12e-05	385
GO:0001525	GO:0001525	angiogenesis	81/1216	342/8380	1.63	2.81e-06	2.24e-05	342
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	14/1216	26/8380	3.71	2.97e-06	2.36e-05	26
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	30/1216	88/8380	2.35	2.99e-06	2.37e-05	88
GO:0002335	GO:0002335	mature B cell differentiation	11/1216	17/8380	4.46	3.07e-06	2.41e-05	17
GO:0002407	GO:0002407	dendritic cell chemotaxis	11/1216	17/8380	4.46	3.07e-06	2.41e-05	17
GO:2000108	GO:2000108	positive regulation of leukocyte apoptotic process	11/1216	17/8380	4.46	3.07e-06	2.41e-05	17
GO:0007599	GO:0007599	hemostasis	54/1216	202/8380	1.84	3.28e-06	2.58e-05	202
GO:0001782	GO:0001782	B cell homeostasis	12/1216	20/8380	4.13	3.36e-06	2.63e-05	20
GO:2000257	GO:2000257	regulation of protein activation cascade	18/1216	40/8380	3.10	3.39e-06	2.65e-05	40
GO:0050709	GO:0050709	negative regulation of protein secretion	28/1216	80/8380	2.41	3.54e-06	2.76e-05	80
GO:0061900	GO:0061900	glial cell activation	16/1216	33/8380	3.34	3.55e-06	2.76e-05	33
GO:0046718	GO:0046718	viral entry into host cell	27/1216	76/8380	2.45	3.81e-06	2.96e-05	76
GO:0070201	GO:0070201	regulation of establishment of protein localization	88/1216	383/8380	1.58	3.95e-06	3.06e-05	383
GO:2001185	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	9/1216	12/8380	5.17	4.03e-06	3.12e-05	12
GO:0050706	GO:0050706	regulation of interleukin-1 beta secretion	15/1216	30/8380	3.45	4.42e-06	3.41e-05	30
GO:0002220	GO:0002220	innate immune response activating cell surface receptor signaling pathway	18/1216	41/8380	3.03	5.23e-06	4.02e-05	41
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	14/1216	27/8380	3.57	5.35e-06	4.11e-05	27
GO:0007229	GO:0007229	integrin-mediated signaling pathway	26/1216	73/8380	2.45	5.44e-06	4.17e-05	73
GO:0001894	GO:0001894	tissue homeostasis	42/1216	146/8380	1.98	5.64e-06	4.31e-05	146
GO:0051222	GO:0051222	positive regulation of protein transport	58/1216	226/8380	1.77	5.78e-06	4.41e-05	226
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	16/1216	34/8380	3.24	5.81e-06	4.43e-05	34
GO:0045061	GO:0045061	thymic T cell selection	10/1216	15/8380	4.59	5.98e-06	4.54e-05	15
GO:0002828	GO:0002828	regulation of type 2 immune response	13/1216	24/8380	3.73	6.21e-06	4.70e-05	24
GO:0072677	GO:0072677	eosinophil migration	13/1216	24/8380	3.73	6.21e-06	4.70e-05	24
GO:0002430	GO:0002430	complement receptor mediated signaling pathway	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0002517	GO:0002517	T cell tolerance induction	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0035747	GO:0035747	natural killer cell chemotaxis	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0036005	GO:0036005	response to macrophage colony-stimulating factor	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0036006	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0043383	GO:0043383	negative T cell selection	8/1216	10/8380	5.51	6.59e-06	4.92e-05	10
GO:0002639	GO:0002639	positive regulation of immunoglobulin production	12/1216	21/8380	3.94	6.81e-06	5.07e-05	21
GO:0002888	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	11/1216	18/8380	4.21	6.85e-06	5.07e-05	18
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	11/1216	18/8380	4.21	6.85e-06	5.07e-05	18
GO:0035590	GO:0035590	purinergic nucleotide receptor signaling pathway	11/1216	18/8380	4.21	6.85e-06	5.07e-05	18
GO:0042130	GO:0042130	negative regulation of T cell proliferation	17/1216	38/8380	3.08	7.00e-06	5.18e-05	38
GO:0032722	GO:0032722	positive regulation of chemokine production	18/1216	42/8380	2.95	7.92e-06	5.84e-05	42
GO:0050848	GO:0050848	regulation of calcium-mediated signaling	23/1216	62/8380	2.56	8.63e-06	6.35e-05	62
GO:0051235	GO:0051235	maintenance of location	51/1216	193/8380	1.82	8.75e-06	6.43e-05	193
GO:0048010	GO:0048010	vascular endothelial growth factor receptor signaling pathway	20/1216	50/8380	2.76	8.90e-06	6.52e-05	50
GO:0006956	GO:0006956	complement activation	21/1216	54/8380	2.68	9.00e-06	6.58e-05	54
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	16/1216	35/8380	3.15	9.28e-06	6.76e-05	35
GO:0038083	GO:0038083	peptidyl-tyrosine autophosphorylation	14/1216	28/8380	3.45	9.28e-06	6.76e-05	28
GO:0051048	GO:0051048	negative regulation of secretion	42/1216	149/8380	1.94	9.86e-06	7.17e-05	149
GO:1904951	GO:1904951	positive regulation of establishment of protein localization	59/1216	235/8380	1.73	1.00e-05	7.27e-05	235
GO:0007596	GO:0007596	blood coagulation	52/1216	199/8380	1.80	1.01e-05	7.32e-05	199
GO:0032102	GO:0032102	negative regulation of response to external stimulus	55/1216	215/8380	1.76	1.11e-05	8.04e-05	215
GO:0002381	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	13/1216	25/8380	3.58	1.12e-05	8.09e-05	25
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	13/1216	25/8380	3.58	1.12e-05	8.09e-05	25
GO:0045072	GO:0045072	regulation of interferon-gamma biosynthetic process	9/1216	13/8380	4.77	1.14e-05	8.20e-05	13
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	18/1216	43/8380	2.88	1.18e-05	8.45e-05	43
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	15/1216	32/8380	3.23	1.21e-05	8.67e-05	32
GO:0070613	GO:0070613	regulation of protein processing	26/1216	76/8380	2.36	1.26e-05	8.98e-05	76
GO:0050901	GO:0050901	leukocyte tethering or rolling	12/1216	22/8380	3.76	1.30e-05	9.27e-05	22
GO:0043900	GO:0043900	regulation of multi-organism process	50/1216	191/8380	1.80	1.41e-05	1.01e-04	191
GO:0030260	GO:0030260	entry into host cell	27/1216	81/8380	2.30	1.48e-05	1.05e-04	81
GO:0044409	GO:0044409	entry into host	27/1216	81/8380	2.30	1.48e-05	1.05e-04	81
GO:0051806	GO:0051806	entry into cell of other organism involved in symbiotic interaction	27/1216	81/8380	2.30	1.48e-05	1.05e-04	81
GO:0051828	GO:0051828	entry into other organism involved in symbiotic interaction	27/1216	81/8380	2.30	1.48e-05	1.05e-04	81
GO:0050817	GO:0050817	coagulation	52/1216	202/8380	1.77	1.59e-05	1.12e-04	202
GO:0033674	GO:0033674	positive regulation of kinase activity	76/1216	330/8380	1.59	1.67e-05	1.17e-04	330
GO:0072593	GO:0072593	reactive oxygen species metabolic process	44/1216	162/8380	1.87	1.71e-05	1.20e-04	162
GO:0032642	GO:0032642	regulation of chemokine production	21/1216	56/8380	2.58	1.74e-05	1.22e-04	56
GO:0097190	GO:0097190	apoptotic signaling pathway	68/1216	287/8380	1.63	1.76e-05	1.23e-04	287
GO:0032755	GO:0032755	positive regulation of interleukin-6 production	20/1216	52/8380	2.65	1.78e-05	1.24e-04	52
GO:0070231	GO:0070231	T cell apoptotic process	15/1216	33/8380	3.13	1.93e-05	1.34e-04	33
GO:0002369	GO:0002369	T cell cytokine production	13/1216	26/8380	3.45	1.95e-05	1.35e-04	26
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	13/1216	26/8380	3.45	1.95e-05	1.35e-04	26
GO:0032481	GO:0032481	positive regulation of type I interferon production	13/1216	26/8380	3.45	1.95e-05	1.35e-04	26
GO:0042092	GO:0042092	type 2 immune response	13/1216	26/8380	3.45	1.95e-05	1.35e-04	26
GO:0006816	GO:0006816	calcium ion transport	65/1216	272/8380	1.65	2.01e-05	1.39e-04	272
GO:0001771	GO:0001771	immunological synapse formation	8/1216	11/8380	5.01	2.11e-05	1.44e-04	11
GO:0032740	GO:0032740	positive regulation of interleukin-17 production	8/1216	11/8380	5.01	2.11e-05	1.44e-04	11
GO:0051023	GO:0051023	regulation of immunoglobulin secretion	8/1216	11/8380	5.01	2.11e-05	1.44e-04	11
GO:1903317	GO:1903317	regulation of protein maturation	26/1216	78/8380	2.30	2.13e-05	1.45e-04	78
GO:0051224	GO:0051224	negative regulation of protein transport	31/1216	101/8380	2.12	2.33e-05	1.59e-04	101
GO:0050856	GO:0050856	regulation of T cell receptor signaling pathway	12/1216	23/8380	3.60	2.36e-05	1.61e-04	23
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	14/1216	30/8380	3.22	2.53e-05	1.72e-04	30
GO:0045824	GO:0045824	negative regulation of innate immune response	14/1216	30/8380	3.22	2.53e-05	1.72e-04	30
GO:0043032	GO:0043032	positive regulation of macrophage activation	11/1216	20/8380	3.79	2.73e-05	1.85e-04	20
GO:0072606	GO:0072606	interleukin-8 secretion	11/1216	20/8380	3.79	2.73e-05	1.85e-04	20
GO:0035589	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	9/1216	14/8380	4.43	2.78e-05	1.88e-04	14
GO:0051924	GO:0051924	regulation of calcium ion transport	44/1216	165/8380	1.84	2.81e-05	1.89e-04	165
GO:0002831	GO:0002831	regulation of response to biotic stimulus	23/1216	66/8380	2.40	2.81e-05	1.89e-04	66
GO:1904950	GO:1904950	negative regulation of establishment of protein localization	31/1216	102/8380	2.09	2.89e-05	1.94e-04	102
GO:0009595	GO:0009595	detection of biotic stimulus	10/1216	17/8380	4.05	2.93e-05	1.95e-04	17
GO:0045671	GO:0045671	negative regulation of osteoclast differentiation	10/1216	17/8380	4.05	2.93e-05	1.95e-04	17
GO:2000482	GO:2000482	regulation of interleukin-8 secretion	10/1216	17/8380	4.05	2.93e-05	1.95e-04	17
GO:0006898	GO:0006898	receptor-mediated endocytosis	48/1216	186/8380	1.78	3.12e-05	2.08e-04	186
GO:0035587	GO:0035587	purinergic receptor signaling pathway	13/1216	27/8380	3.32	3.26e-05	2.17e-04	27
GO:0002223	GO:0002223	stimulatory C-type lectin receptor signaling pathway	16/1216	38/8380	2.90	3.30e-05	2.19e-04	38
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	43/1216	161/8380	1.84	3.31e-05	2.19e-04	161
GO:0048514	GO:0048514	blood vessel morphogenesis	88/1216	404/8380	1.50	3.56e-05	2.35e-04	404
GO:0043281	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	32/1216	108/8380	2.04	3.79e-05	2.50e-04	108
GO:0072511	GO:0072511	divalent inorganic cation transport	69/1216	299/8380	1.59	3.81e-05	2.51e-04	299
GO:1902622	GO:1902622	regulation of neutrophil migration	12/1216	24/8380	3.45	4.10e-05	2.70e-04	24
GO:2000116	GO:2000116	regulation of cysteine-type endopeptidase activity	35/1216	123/8380	1.96	4.29e-05	2.82e-04	123
GO:0150077	GO:0150077	regulation of neuroinflammatory response	11/1216	21/8380	3.61	4.98e-05	3.26e-04	21
GO:0002437	GO:0002437	inflammatory response to antigenic stimulus	13/1216	28/8380	3.20	5.29e-05	3.46e-04	28
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	37/1216	134/8380	1.90	5.36e-05	3.50e-04	134
GO:1903707	GO:1903707	negative regulation of hemopoiesis	28/1216	91/8380	2.12	5.44e-05	3.54e-04	91
GO:0070838	GO:0070838	divalent metal ion transport	68/1216	297/8380	1.58	5.63e-05	3.66e-04	297
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	9/1216	15/8380	4.13	6.06e-05	3.94e-04	15
GO:0033627	GO:0033627	cell adhesion mediated by integrin	19/1216	52/8380	2.52	6.60e-05	4.28e-04	52
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	15/1216	36/8380	2.87	6.74e-05	4.36e-04	36
GO:0002534	GO:0002534	cytokine production involved in inflammatory response	12/1216	25/8380	3.31	6.86e-05	4.42e-04	25
GO:0002675	GO:0002675	positive regulation of acute inflammatory response	12/1216	25/8380	3.31	6.86e-05	4.42e-04	25
GO:0034103	GO:0034103	regulation of tissue remodeling	18/1216	48/8380	2.58	6.89e-05	4.43e-04	48
GO:0043550	GO:0043550	regulation of lipid kinase activity	16/1216	40/8380	2.76	7.01e-05	4.50e-04	40
GO:0051051	GO:0051051	negative regulation of transport	66/1216	289/8380	1.57	7.84e-05	5.02e-04	289
GO:0072376	GO:0072376	protein activation cascade	23/1216	70/8380	2.26	8.09e-05	5.17e-04	70
GO:0070232	GO:0070232	regulation of T cell apoptotic process	13/1216	29/8380	3.09	8.32e-05	5.31e-04	29
GO:0042554	GO:0042554	superoxide anion generation	11/1216	22/8380	3.45	8.66e-05	5.49e-04	22
GO:0050718	GO:0050718	positive regulation of interleukin-1 beta secretion	11/1216	22/8380	3.45	8.66e-05	5.49e-04	22
GO:0070670	GO:0070670	response to interleukin-4	11/1216	22/8380	3.45	8.66e-05	5.49e-04	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	11/1216	22/8380	3.45	8.66e-05	5.49e-04	22
GO:0016485	GO:0016485	protein processing	40/1216	152/8380	1.81	8.82e-05	5.58e-04	152
GO:1903725	GO:1903725	regulation of phospholipid metabolic process	19/1216	53/8380	2.47	8.91e-05	5.63e-04	53
GO:0051701	GO:0051701	interaction with host	30/1216	103/8380	2.01	9.31e-05	5.87e-04	103
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	15/1216	37/8380	2.79	9.82e-05	6.17e-04	37
GO:1905517	GO:1905517	macrophage migration	15/1216	37/8380	2.79	9.82e-05	6.17e-04	37
GO:0045577	GO:0045577	regulation of B cell differentiation	10/1216	19/8380	3.63	1.05e-04	6.60e-04	19
GO:0090025	GO:0090025	regulation of monocyte chemotaxis	10/1216	19/8380	3.63	1.05e-04	6.60e-04	19
GO:0002467	GO:0002467	germinal center formation	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0032490	GO:0032490	detection of molecule of bacterial origin	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0033004	GO:0033004	negative regulation of mast cell activation	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0043374	GO:0043374	CD8-positive, alpha-beta T cell differentiation	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0045591	GO:0045591	positive regulation of regulatory T cell differentiation	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:0070230	GO:0070230	positive regulation of lymphocyte apoptotic process	7/1216	10/8380	4.82	1.07e-04	6.61e-04	10
GO:1905521	GO:1905521	regulation of macrophage migration	12/1216	26/8380	3.18	1.11e-04	6.83e-04	26
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	9/1216	16/8380	3.88	1.21e-04	7.41e-04	16
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	9/1216	16/8380	3.88	1.21e-04	7.41e-04	16
GO:0071677	GO:0071677	positive regulation of mononuclear cell migration	9/1216	16/8380	3.88	1.21e-04	7.41e-04	16
GO:0072538	GO:0072538	T-helper 17 type immune response	9/1216	16/8380	3.88	1.21e-04	7.41e-04	16
GO:0002726	GO:0002726	positive regulation of T cell cytokine production	8/1216	13/8380	4.24	1.25e-04	7.61e-04	13
GO:0006925	GO:0006925	inflammatory cell apoptotic process	8/1216	13/8380	4.24	1.25e-04	7.61e-04	13
GO:0010919	GO:0010919	regulation of inositol phosphate biosynthetic process	8/1216	13/8380	4.24	1.25e-04	7.61e-04	13
GO:0032604	GO:0032604	granulocyte macrophage colony-stimulating factor production	8/1216	13/8380	4.24	1.25e-04	7.61e-04	13
GO:0090026	GO:0090026	positive regulation of monocyte chemotaxis	8/1216	13/8380	4.24	1.25e-04	7.61e-04	13
GO:0045860	GO:0045860	positive regulation of protein kinase activity	69/1216	310/8380	1.53	1.25e-04	7.61e-04	310
GO:0046209	GO:0046209	nitric oxide metabolic process	18/1216	50/8380	2.48	1.28e-04	7.74e-04	50
GO:0035588	GO:0035588	G protein-coupled purinergic receptor signaling pathway	11/1216	23/8380	3.30	1.44e-04	8.67e-04	23
GO:2000249	GO:2000249	regulation of actin cytoskeleton reorganization	11/1216	23/8380	3.30	1.44e-04	8.67e-04	23
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	22/1216	68/8380	2.23	1.49e-04	8.89e-04	68
GO:0048871	GO:0048871	multicellular organismal homeostasis	69/1216	312/8380	1.52	1.54e-04	9.20e-04	312
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	19/1216	55/8380	2.38	1.58e-04	9.40e-04	55
GO:0010543	GO:0010543	regulation of platelet activation	12/1216	27/8380	3.06	1.73e-04	1.03e-03	27
GO:0030225	GO:0030225	macrophage differentiation	12/1216	27/8380	3.06	1.73e-04	1.03e-03	27
GO:0031331	GO:0031331	positive regulation of cellular catabolic process	35/1216	131/8380	1.84	1.73e-04	1.03e-03	131
GO:0002724	GO:0002724	regulation of T cell cytokine production	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:0032814	GO:0032814	regulation of natural killer cell activation	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:0048245	GO:0048245	eosinophil chemotaxis	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:0071353	GO:0071353	cellular response to interleukin-4	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:0090322	GO:0090322	regulation of superoxide metabolic process	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:1902624	GO:1902624	positive regulation of neutrophil migration	10/1216	20/8380	3.45	1.83e-04	1.08e-03	20
GO:0032732	GO:0032732	positive regulation of interleukin-1 production	13/1216	31/8380	2.89	1.91e-04	1.12e-03	31
GO:0010950	GO:0010950	positive regulation of endopeptidase activity	26/1216	88/8380	2.04	2.08e-04	1.21e-03	88
GO:0050878	GO:0050878	regulation of body fluid levels	69/1216	315/8380	1.51	2.08e-04	1.21e-03	315
GO:0070588	GO:0070588	calcium ion transmembrane transport	48/1216	200/8380	1.65	2.15e-04	1.25e-03	200
GO:0043491	GO:0043491	protein kinase B signaling	39/1216	153/8380	1.76	2.23e-04	1.30e-03	153
GO:0042832	GO:0042832	defense response to protozoan	9/1216	17/8380	3.65	2.24e-04	1.30e-03	17
GO:2001057	GO:2001057	reactive nitrogen species metabolic process	18/1216	52/8380	2.39	2.27e-04	1.31e-03	52
GO:0030224	GO:0030224	monocyte differentiation	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0034142	GO:0034142	toll-like receptor 4 signaling pathway	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0043552	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0050716	GO:0050716	positive regulation of interleukin-1 secretion	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:1903131	GO:1903131	mononuclear cell differentiation	11/1216	24/8380	3.16	2.32e-04	1.33e-03	24
GO:0046777	GO:0046777	protein autophosphorylation	33/1216	123/8380	1.85	2.41e-04	1.38e-03	123
GO:0032147	GO:0032147	activation of protein kinase activity	45/1216	185/8380	1.68	2.42e-04	1.38e-03	185
GO:0006809	GO:0006809	nitric oxide biosynthetic process	17/1216	48/8380	2.44	2.46e-04	1.40e-03	48
GO:0043405	GO:0043405	regulation of MAP kinase activity	50/1216	212/8380	1.63	2.51e-04	1.43e-03	212
GO:0071902	GO:0071902	positive regulation of protein serine/threonine kinase activity	47/1216	196/8380	1.65	2.54e-04	1.43e-03	196
GO:0002313	GO:0002313	mature B cell differentiation involved in immune response	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0043302	GO:0043302	positive regulation of leukocyte degranulation	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0046639	GO:0046639	negative regulation of alpha-beta T cell differentiation	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0097242	GO:0097242	amyloid-beta clearance	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0098581	GO:0098581	detection of external biotic stimulus	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0140131	GO:0140131	positive regulation of lymphocyte chemotaxis	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0150078	GO:0150078	positive regulation of neuroinflammatory response	8/1216	14/8380	3.94	2.55e-04	1.43e-03	14
GO:0010715	GO:0010715	regulation of extracellular matrix disassembly	7/1216	11/8380	4.39	2.57e-04	1.43e-03	11
GO:0034134	GO:0034134	toll-like receptor 2 signaling pathway	7/1216	11/8380	4.39	2.57e-04	1.43e-03	11
GO:0043011	GO:0043011	myeloid dendritic cell differentiation	7/1216	11/8380	4.39	2.57e-04	1.43e-03	11
GO:0043371	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	7/1216	11/8380	4.39	2.57e-04	1.43e-03	11
GO:0043373	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	7/1216	11/8380	4.39	2.57e-04	1.43e-03	11
GO:0006919	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	16/1216	44/8380	2.51	2.63e-04	1.45e-03	44
GO:0032731	GO:0032731	positive regulation of interleukin-1 beta production	12/1216	28/8380	2.95	2.63e-04	1.45e-03	28
GO:0043277	GO:0043277	apoptotic cell clearance	12/1216	28/8380	2.95	2.63e-04	1.45e-03	28
GO:0045124	GO:0045124	regulation of bone resorption	12/1216	28/8380	2.95	2.63e-04	1.45e-03	28
GO:0008360	GO:0008360	regulation of cell shape	27/1216	94/8380	1.98	2.64e-04	1.46e-03	94
GO:0052548	GO:0052548	regulation of endopeptidase activity	57/1216	251/8380	1.56	2.77e-04	1.53e-03	251
GO:0002686	GO:0002686	negative regulation of leukocyte migration	14/1216	36/8380	2.68	2.82e-04	1.55e-03	36
GO:0046456	GO:0046456	icosanoid biosynthetic process	14/1216	36/8380	2.68	2.82e-04	1.55e-03	36
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	10/1216	21/8380	3.28	3.05e-04	1.67e-03	21
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	31/1216	115/8380	1.86	3.36e-04	1.84e-03	115
GO:0051604	GO:0051604	protein maturation	42/1216	172/8380	1.68	3.53e-04	1.93e-03	172
GO:0006958	GO:0006958	complement activation, classical pathway	11/1216	25/8380	3.03	3.60e-04	1.96e-03	25
GO:0045581	GO:0045581	negative regulation of T cell differentiation	11/1216	25/8380	3.03	3.60e-04	1.96e-03	25
GO:0045862	GO:0045862	positive regulation of proteolysis	40/1216	162/8380	1.70	3.80e-04	2.06e-03	162
GO:0001562	GO:0001562	response to protozoan	9/1216	18/8380	3.45	3.90e-04	2.11e-03	18
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	9/1216	18/8380	3.45	3.90e-04	2.11e-03	18
GO:1903727	GO:1903727	positive regulation of phospholipid metabolic process	13/1216	33/8380	2.71	3.99e-04	2.16e-03	33
GO:0043406	GO:0043406	positive regulation of MAP kinase activity	41/1216	168/8380	1.68	4.19e-04	2.26e-03	168
GO:1903409	GO:1903409	reactive oxygen species biosynthetic process	21/1216	68/8380	2.13	4.28e-04	2.30e-03	68
GO:0010517	GO:0010517	regulation of phospholipase activity	17/1216	50/8380	2.34	4.28e-04	2.30e-03	50
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	17/1216	50/8380	2.34	4.28e-04	2.30e-03	50
GO:1904894	GO:1904894	positive regulation of STAT cascade	19/1216	59/8380	2.22	4.41e-04	2.37e-03	59
GO:0001779	GO:0001779	natural killer cell differentiation	8/1216	15/8380	3.68	4.77e-04	2.55e-03	15
GO:0032691	GO:0032691	negative regulation of interleukin-1 beta production	8/1216	15/8380	3.68	4.77e-04	2.55e-03	15
GO:0055094	GO:0055094	response to lipoprotein particle	8/1216	15/8380	3.68	4.77e-04	2.55e-03	15
GO:0072539	GO:0072539	T-helper 17 cell differentiation	8/1216	15/8380	3.68	4.77e-04	2.55e-03	15
GO:0007202	GO:0007202	activation of phospholipase C activity	10/1216	22/8380	3.13	4.87e-04	2.60e-03	22
GO:0051928	GO:0051928	positive regulation of calcium ion transport	23/1216	78/8380	2.03	4.89e-04	2.60e-03	78
GO:0097696	GO:0097696	STAT cascade	24/1216	83/8380	1.99	5.11e-04	2.72e-03	83
GO:0042136	GO:0042136	neurotransmitter biosynthetic process	21/1216	69/8380	2.10	5.32e-04	2.83e-03	69
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0002418	GO:0002418	immune response to tumor cell	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0032495	GO:0032495	response to muramyl dipeptide	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0032645	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0034162	GO:0034162	toll-like receptor 9 signaling pathway	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0046629	GO:0046629	gamma-delta T cell activation	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:1904994	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:1905523	GO:1905523	positive regulation of macrophage migration	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:2000484	GO:2000484	positive regulation of interleukin-8 secretion	7/1216	12/8380	4.02	5.40e-04	2.83e-03	12
GO:0045428	GO:0045428	regulation of nitric oxide biosynthetic process	14/1216	38/8380	2.54	5.41e-04	2.83e-03	38
GO:0050850	GO:0050850	positive regulation of calcium-mediated signaling	11/1216	26/8380	2.92	5.43e-04	2.83e-03	26
GO:0090218	GO:0090218	positive regulation of lipid kinase activity	11/1216	26/8380	2.92	5.43e-04	2.83e-03	26
GO:1903053	GO:1903053	regulation of extracellular matrix organization	11/1216	26/8380	2.92	5.43e-04	2.83e-03	26
GO:0014068	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	17/1216	51/8380	2.30	5.57e-04	2.89e-03	51
GO:0002763	GO:0002763	positive regulation of myeloid leukocyte differentiation	13/1216	34/8380	2.63	5.62e-04	2.92e-03	34
GO:0043901	GO:0043901	negative regulation of multi-organism process	25/1216	89/8380	1.94	6.35e-04	3.29e-03	89
GO:0045639	GO:0045639	positive regulation of myeloid cell differentiation	18/1216	56/8380	2.22	6.35e-04	3.29e-03	56
GO:0032692	GO:0032692	negative regulation of interleukin-1 production	9/1216	19/8380	3.26	6.46e-04	3.33e-03	19
GO:0032958	GO:0032958	inositol phosphate biosynthetic process	9/1216	19/8380	3.26	6.46e-04	3.33e-03	19
GO:0034105	GO:0034105	positive regulation of tissue remodeling	9/1216	19/8380	3.26	6.46e-04	3.33e-03	19
GO:0045920	GO:0045920	negative regulation of exocytosis	9/1216	19/8380	3.26	6.46e-04	3.33e-03	19
GO:0007259	GO:0007259	JAK-STAT cascade	23/1216	80/8380	1.98	7.25e-04	3.72e-03	80
GO:0030866	GO:0030866	cortical actin cytoskeleton organization	10/1216	23/8380	3.00	7.50e-04	3.84e-03	23
GO:1900015	GO:1900015	regulation of cytokine production involved in inflammatory response	10/1216	23/8380	3.00	7.50e-04	3.84e-03	23
GO:0045766	GO:0045766	positive regulation of angiogenesis	29/1216	110/8380	1.82	7.65e-04	3.91e-03	110
GO:1903305	GO:1903305	regulation of regulated secretory pathway	28/1216	105/8380	1.84	7.71e-04	3.93e-03	105
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	18/1216	57/8380	2.18	8.05e-04	4.10e-03	57
GO:0002360	GO:0002360	T cell lineage commitment	8/1216	16/8380	3.45	8.33e-04	4.23e-03	16
GO:0071402	GO:0071402	cellular response to lipoprotein particle stimulus	8/1216	16/8380	3.45	8.33e-04	4.23e-03	16
GO:0042133	GO:0042133	neurotransmitter metabolic process	27/1216	101/8380	1.84	9.12e-04	4.61e-03	101
GO:0045765	GO:0045765	regulation of angiogenesis	44/1216	191/8380	1.59	9.73e-04	4.91e-03	191
GO:0002710	GO:0002710	negative regulation of T cell mediated immunity	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:0032728	GO:0032728	positive regulation of interferon-beta production	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:0032928	GO:0032928	regulation of superoxide anion generation	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:0045911	GO:0045911	positive regulation of DNA recombination	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:1903978	GO:1903978	regulation of microglial cell activation	7/1216	13/8380	3.71	1.02e-03	5.09e-03	13
GO:0002691	GO:0002691	regulation of cellular extravasation	9/1216	20/8380	3.10	1.03e-03	5.09e-03	20
GO:0032608	GO:0032608	interferon-beta production	9/1216	20/8380	3.10	1.03e-03	5.09e-03	20
GO:0032648	GO:0032648	regulation of interferon-beta production	9/1216	20/8380	3.10	1.03e-03	5.09e-03	20
GO:0033028	GO:0033028	myeloid cell apoptotic process	9/1216	20/8380	3.10	1.03e-03	5.09e-03	20
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	9/1216	20/8380	3.10	1.03e-03	5.09e-03	20
GO:0001659	GO:0001659	temperature homeostasis	29/1216	112/8380	1.78	1.05e-03	5.18e-03	112
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	24/1216	87/8380	1.90	1.07e-03	5.30e-03	87
GO:2000377	GO:2000377	regulation of reactive oxygen species metabolic process	27/1216	102/8380	1.82	1.07e-03	5.31e-03	102
GO:0017157	GO:0017157	regulation of exocytosis	33/1216	133/8380	1.71	1.09e-03	5.37e-03	133
GO:0030193	GO:0030193	regulation of blood coagulation	19/1216	63/8380	2.08	1.09e-03	5.37e-03	63
GO:0043280	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	19/1216	63/8380	2.08	1.09e-03	5.37e-03	63
GO:1900046	GO:1900046	regulation of hemostasis	19/1216	63/8380	2.08	1.09e-03	5.37e-03	63
GO:0010863	GO:0010863	positive regulation of phospholipase C activity	12/1216	32/8380	2.58	1.12e-03	5.48e-03	32
GO:0043029	GO:0043029	T cell homeostasis	10/1216	24/8380	2.87	1.12e-03	5.49e-03	24
GO:0002200	GO:0002200	somatic diversification of immune receptors	11/1216	28/8380	2.71	1.14e-03	5.49e-03	28
GO:0009620	GO:0009620	response to fungus	11/1216	28/8380	2.71	1.14e-03	5.49e-03	28
GO:0010573	GO:0010573	vascular endothelial growth factor production	11/1216	28/8380	2.71	1.14e-03	5.49e-03	28
GO:0002295	GO:0002295	T-helper cell lineage commitment	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0002834	GO:0002834	regulation of response to tumor cell	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0002837	GO:0002837	regulation of immune response to tumor cell	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0010759	GO:0010759	positive regulation of macrophage chemotaxis	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0010819	GO:0010819	regulation of T cell chemotaxis	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0032494	GO:0032494	response to peptidoglycan	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0042226	GO:0042226	interleukin-6 biosynthetic process	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0042535	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0042976	GO:0042976	activation of Janus kinase activity	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0045623	GO:0045623	negative regulation of T-helper cell differentiation	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0045830	GO:0045830	positive regulation of isotype switching	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0070486	GO:0070486	leukocyte aggregation	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0071800	GO:0071800	podosome assembly	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0098543	GO:0098543	detection of other organism	6/1216	10/8380	4.13	1.15e-03	5.49e-03	10
GO:0050830	GO:0050830	defense response to Gram-positive bacterium	17/1216	54/8380	2.17	1.16e-03	5.55e-03	54
GO:0048015	GO:0048015	phosphatidylinositol-mediated signaling	27/1216	103/8380	1.81	1.26e-03	6.01e-03	103
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	23/1216	83/8380	1.91	1.26e-03	6.02e-03	83
GO:0010952	GO:0010952	positive regulation of peptidase activity	26/1216	98/8380	1.83	1.27e-03	6.05e-03	98
GO:0010518	GO:0010518	positive regulation of phospholipase activity	14/1216	41/8380	2.35	1.29e-03	6.14e-03	41
GO:0007260	GO:0007260	tyrosine phosphorylation of STAT protein	16/1216	50/8380	2.21	1.32e-03	6.28e-03	50
GO:0035743	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	8/1216	17/8380	3.24	1.38e-03	6.53e-03	17
GO:0051896	GO:0051896	regulation of protein kinase B signaling	33/1216	135/8380	1.68	1.43e-03	6.77e-03	135
GO:0002262	GO:0002262	myeloid cell homeostasis	21/1216	74/8380	1.96	1.46e-03	6.88e-03	74
GO:2001056	GO:2001056	positive regulation of cysteine-type endopeptidase activity	21/1216	74/8380	1.96	1.46e-03	6.88e-03	74
GO:0034113	GO:0034113	heterotypic cell-cell adhesion	15/1216	46/8380	2.25	1.50e-03	7.07e-03	46
GO:0000187	GO:0000187	activation of MAPK activity	25/1216	94/8380	1.83	1.50e-03	7.08e-03	94
GO:0001935	GO:0001935	endothelial cell proliferation	25/1216	94/8380	1.83	1.50e-03	7.08e-03	94
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	12/1216	33/8380	2.51	1.53e-03	7.14e-03	33
GO:0002762	GO:0002762	negative regulation of myeloid leukocyte differentiation	12/1216	33/8380	2.51	1.53e-03	7.14e-03	33
GO:0046850	GO:0046850	regulation of bone remodeling	12/1216	33/8380	2.51	1.53e-03	7.14e-03	33
GO:1900274	GO:1900274	regulation of phospholipase C activity	12/1216	33/8380	2.51	1.53e-03	7.14e-03	33
GO:0006509	GO:0006509	membrane protein ectodomain proteolysis	9/1216	21/8380	2.95	1.57e-03	7.29e-03	21
GO:1902932	GO:1902932	positive regulation of alcohol biosynthetic process	9/1216	21/8380	2.95	1.57e-03	7.29e-03	21
GO:1904646	GO:1904646	cellular response to amyloid-beta	9/1216	21/8380	2.95	1.57e-03	7.29e-03	21
GO:0050688	GO:0050688	regulation of defense response to virus	11/1216	29/8380	2.61	1.60e-03	7.46e-03	29
GO:0030865	GO:0030865	cortical cytoskeleton organization	10/1216	25/8380	2.76	1.63e-03	7.57e-03	25
GO:0031334	GO:0031334	positive regulation of protein complex assembly	29/1216	115/8380	1.74	1.63e-03	7.57e-03	115
GO:0050818	GO:0050818	regulation of coagulation	19/1216	65/8380	2.01	1.65e-03	7.64e-03	65
GO:0060337	GO:0060337	type I interferon signaling pathway	16/1216	51/8380	2.16	1.67e-03	7.72e-03	51
GO:0071357	GO:0071357	cellular response to type I interferon	16/1216	51/8380	2.16	1.67e-03	7.72e-03	51
GO:0048017	GO:0048017	inositol lipid-mediated signaling	27/1216	105/8380	1.77	1.71e-03	7.90e-03	105
GO:1904892	GO:1904892	regulation of STAT cascade	21/1216	75/8380	1.93	1.75e-03	8.08e-03	75
GO:0043254	GO:0043254	regulation of protein complex assembly	45/1216	202/8380	1.54	1.77e-03	8.16e-03	202
GO:0045191	GO:0045191	regulation of isotype switching	7/1216	14/8380	3.45	1.79e-03	8.22e-03	14
GO:0072643	GO:0072643	interferon-gamma secretion	7/1216	14/8380	3.45	1.79e-03	8.22e-03	14
GO:1901739	GO:1901739	regulation of myoblast fusion	7/1216	14/8380	3.45	1.79e-03	8.22e-03	14
GO:0070527	GO:0070527	platelet aggregation	13/1216	38/8380	2.36	1.87e-03	8.57e-03	38
GO:0007254	GO:0007254	JNK cascade	31/1216	127/8380	1.68	2.01e-03	9.19e-03	127
GO:0033628	GO:0033628	regulation of cell adhesion mediated by integrin	12/1216	34/8380	2.43	2.05e-03	9.36e-03	34
GO:0046330	GO:0046330	positive regulation of JNK cascade	25/1216	96/8380	1.79	2.07e-03	9.42e-03	96
GO:0034340	GO:0034340	response to type I interferon	16/1216	52/8380	2.12	2.09e-03	9.53e-03	52
GO:0002576	GO:0002576	platelet degranulation	23/1216	86/8380	1.84	2.11e-03	9.59e-03	86
GO:0002719	GO:0002719	negative regulation of cytokine production involved in immune response	8/1216	18/8380	3.06	2.16e-03	9.78e-03	18
GO:0032703	GO:0032703	negative regulation of interleukin-2 production	8/1216	18/8380	3.06	2.16e-03	9.78e-03	18
GO:0033032	GO:0033032	regulation of myeloid cell apoptotic process	8/1216	18/8380	3.06	2.16e-03	9.78e-03	18
GO:0060142	GO:0060142	regulation of syncytium formation by plasma membrane fusion	8/1216	18/8380	3.06	2.16e-03	9.78e-03	18
GO:0071354	GO:0071354	cellular response to interleukin-6	8/1216	18/8380	3.06	2.16e-03	9.78e-03	18
GO:0014015	GO:0014015	positive regulation of gliogenesis	14/1216	43/8380	2.24	2.17e-03	9.78e-03	43
GO:0002374	GO:0002374	cytokine secretion involved in immune response	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0032725	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0032816	GO:0032816	positive regulation of natural killer cell activation	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0045064	GO:0045064	T-helper 2 cell differentiation	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0050860	GO:0050860	negative regulation of T cell receptor signaling pathway	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0051044	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0060732	GO:0060732	positive regulation of inositol phosphate biosynthetic process	6/1216	11/8380	3.76	2.21e-03	9.90e-03	11
GO:0070304	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	28/1216	112/8380	1.72	2.23e-03	9.97e-03	112
GO:0002474	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	10/1216	26/8380	2.65	2.31e-03	1.02e-02	26
GO:0002562	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	10/1216	26/8380	2.65	2.31e-03	1.02e-02	26
GO:0010574	GO:0010574	regulation of vascular endothelial growth factor production	10/1216	26/8380	2.65	2.31e-03	1.02e-02	26
GO:0016444	GO:0016444	somatic cell DNA recombination	10/1216	26/8380	2.65	2.31e-03	1.02e-02	26
GO:0070741	GO:0070741	response to interleukin-6	9/1216	22/8380	2.82	2.31e-03	1.03e-02	22
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	18/1216	62/8380	2.00	2.35e-03	1.04e-02	62
GO:0046425	GO:0046425	regulation of JAK-STAT cascade	20/1216	72/8380	1.91	2.47e-03	1.10e-02	72
GO:0043433	GO:0043433	negative regulation of DNA-binding transcription factor activity	21/1216	77/8380	1.88	2.50e-03	1.10e-02	77
GO:0050792	GO:0050792	regulation of viral process	21/1216	77/8380	1.88	2.50e-03	1.10e-02	77
GO:0019079	GO:0019079	viral genome replication	16/1216	53/8380	2.08	2.60e-03	1.15e-02	53
GO:1904018	GO:1904018	positive regulation of vasculature development	30/1216	124/8380	1.67	2.72e-03	1.20e-02	124
GO:1903169	GO:1903169	regulation of calcium ion transmembrane transport	26/1216	103/8380	1.74	2.73e-03	1.20e-02	103
GO:0060191	GO:0060191	regulation of lipase activity	18/1216	63/8380	1.97	2.85e-03	1.25e-02	63
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	19/1216	68/8380	1.93	2.92e-03	1.28e-02	68
GO:0032607	GO:0032607	interferon-alpha production	7/1216	15/8380	3.22	2.94e-03	1.28e-02	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	7/1216	15/8380	3.22	2.94e-03	1.28e-02	15
GO:0048535	GO:0048535	lymph node development	7/1216	15/8380	3.22	2.94e-03	1.28e-02	15
GO:1903306	GO:1903306	negative regulation of regulated secretory pathway	7/1216	15/8380	3.22	2.94e-03	1.28e-02	15
GO:0032088	GO:0032088	negative regulation of NF-kappaB transcription factor activity	11/1216	31/8380	2.45	2.98e-03	1.29e-02	31
GO:0045071	GO:0045071	negative regulation of viral genome replication	11/1216	31/8380	2.45	2.98e-03	1.29e-02	31
GO:0045620	GO:0045620	negative regulation of lymphocyte differentiation	11/1216	31/8380	2.45	2.98e-03	1.29e-02	31
GO:1903428	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	11/1216	31/8380	2.45	2.98e-03	1.29e-02	31
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	15/1216	49/8380	2.11	3.02e-03	1.31e-02	49
GO:0034599	GO:0034599	cellular response to oxidative stress	33/1216	141/8380	1.61	3.05e-03	1.32e-02	141
GO:0009896	GO:0009896	positive regulation of catabolic process	37/1216	163/8380	1.56	3.11e-03	1.35e-02	163
GO:0033619	GO:0033619	membrane protein proteolysis	10/1216	27/8380	2.55	3.19e-03	1.37e-02	27
GO:0045429	GO:0045429	positive regulation of nitric oxide biosynthetic process	10/1216	27/8380	2.55	3.19e-03	1.37e-02	27
GO:0045806	GO:0045806	negative regulation of endocytosis	10/1216	27/8380	2.55	3.19e-03	1.37e-02	27
GO:1904407	GO:1904407	positive regulation of nitric oxide metabolic process	10/1216	27/8380	2.55	3.19e-03	1.37e-02	27
GO:0002204	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0002208	GO:0002208	somatic diversification of immunoglobulins involved in immune response	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0032480	GO:0032480	negative regulation of type I interferon production	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0045190	GO:0045190	isotype switching	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0050691	GO:0050691	regulation of defense response to virus by host	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0070233	GO:0070233	negative regulation of T cell apoptotic process	8/1216	19/8380	2.90	3.27e-03	1.40e-02	19
GO:0010575	GO:0010575	positive regulation of vascular endothelial growth factor production	9/1216	23/8380	2.70	3.31e-03	1.41e-02	23
GO:0016445	GO:0016445	somatic diversification of immunoglobulins	9/1216	23/8380	2.70	3.31e-03	1.41e-02	23
GO:0046173	GO:0046173	polyol biosynthetic process	12/1216	36/8380	2.30	3.54e-03	1.51e-02	36
GO:0031098	GO:0031098	stress-activated protein kinase signaling cascade	38/1216	170/8380	1.54	3.65e-03	1.55e-02	170
GO:2000117	GO:2000117	negative regulation of cysteine-type endopeptidase activity	15/1216	50/8380	2.07	3.74e-03	1.59e-02	50
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	24/1216	95/8380	1.74	3.86e-03	1.63e-02	95
GO:0002693	GO:0002693	positive regulation of cellular extravasation	6/1216	12/8380	3.45	3.89e-03	1.64e-02	12
GO:0032736	GO:0032736	positive regulation of interleukin-13 production	6/1216	12/8380	3.45	3.89e-03	1.64e-02	12
GO:0035872	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	6/1216	12/8380	3.45	3.89e-03	1.64e-02	12
GO:0070423	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	6/1216	12/8380	3.45	3.89e-03	1.64e-02	12
GO:0032874	GO:0032874	positive regulation of stress-activated MAPK cascade	27/1216	111/8380	1.68	4.00e-03	1.68e-02	111
GO:0046488	GO:0046488	phosphatidylinositol metabolic process	29/1216	122/8380	1.64	4.17e-03	1.75e-02	122
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	10/1216	28/8380	2.46	4.33e-03	1.81e-02	28
GO:0019835	GO:0019835	cytolysis	10/1216	28/8380	2.46	4.33e-03	1.81e-02	28
GO:0051482	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	10/1216	28/8380	2.46	4.33e-03	1.81e-02	28
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	14/1216	46/8380	2.10	4.35e-03	1.81e-02	46
GO:0043154	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	14/1216	46/8380	2.10	4.35e-03	1.81e-02	46
GO:0060193	GO:0060193	positive regulation of lipase activity	14/1216	46/8380	2.10	4.35e-03	1.81e-02	46
GO:1902930	GO:1902930	regulation of alcohol biosynthetic process	14/1216	46/8380	2.10	4.35e-03	1.81e-02	46
GO:0046328	GO:0046328	regulation of JNK cascade	28/1216	117/8380	1.65	4.37e-03	1.82e-02	117
GO:0010524	GO:0010524	positive regulation of calcium ion transport into cytosol	12/1216	37/8380	2.24	4.57e-03	1.89e-02	37
GO:0002438	GO:0002438	acute inflammatory response to antigenic stimulus	7/1216	16/8380	3.02	4.58e-03	1.89e-02	16
GO:0032616	GO:0032616	interleukin-13 production	7/1216	16/8380	3.02	4.58e-03	1.89e-02	16
GO:0033622	GO:0033622	integrin activation	7/1216	16/8380	3.02	4.58e-03	1.89e-02	16
GO:1904645	GO:1904645	response to amyloid-beta	9/1216	24/8380	2.58	4.63e-03	1.91e-02	24
GO:0046165	GO:0046165	alcohol biosynthetic process	22/1216	86/8380	1.76	4.70e-03	1.94e-02	86
GO:0010758	GO:0010758	regulation of macrophage chemotaxis	8/1216	20/8380	2.76	4.76e-03	1.96e-02	20
GO:0014013	GO:0014013	regulation of gliogenesis	20/1216	76/8380	1.81	4.88e-03	2.01e-02	76
GO:0070302	GO:0070302	regulation of stress-activated protein kinase signaling cascade	32/1216	140/8380	1.58	5.12e-03	2.10e-02	140
GO:0043507	GO:0043507	positive regulation of JUN kinase activity	14/1216	47/8380	2.05	5.39e-03	2.21e-02	47
GO:0048525	GO:0048525	negative regulation of viral process	14/1216	47/8380	2.05	5.39e-03	2.21e-02	47
GO:0048246	GO:0048246	macrophage chemotaxis	10/1216	29/8380	2.38	5.77e-03	2.36e-02	29
GO:0050798	GO:0050798	activated T cell proliferation	10/1216	29/8380	2.38	5.77e-03	2.36e-02	29
GO:0051403	GO:0051403	stress-activated MAPK cascade	35/1216	158/8380	1.53	5.97e-03	2.44e-02	158
GO:0061041	GO:0061041	regulation of wound healing	23/1216	93/8380	1.70	6.10e-03	2.49e-02	93
GO:0097191	GO:0097191	extrinsic apoptotic signaling pathway	28/1216	120/8380	1.61	6.33e-03	2.56e-02	120
GO:0002756	GO:0002756	MyD88-independent toll-like receptor signaling pathway	6/1216	13/8380	3.18	6.34e-03	2.56e-02	13
GO:0019370	GO:0019370	leukotriene biosynthetic process	6/1216	13/8380	3.18	6.34e-03	2.56e-02	13
GO:0045655	GO:0045655	regulation of monocyte differentiation	6/1216	13/8380	3.18	6.34e-03	2.56e-02	13
GO:1901741	GO:1901741	positive regulation of myoblast fusion	6/1216	13/8380	3.18	6.34e-03	2.56e-02	13
GO:1905153	GO:1905153	regulation of membrane invagination	6/1216	13/8380	3.18	6.34e-03	2.56e-02	13
GO:0016447	GO:0016447	somatic recombination of immunoglobulin gene segments	8/1216	21/8380	2.63	6.73e-03	2.72e-02	21
GO:0042036	GO:0042036	negative regulation of cytokine biosynthetic process	8/1216	21/8380	2.63	6.73e-03	2.72e-02	21
GO:0002347	GO:0002347	response to tumor cell	7/1216	17/8380	2.84	6.83e-03	2.74e-02	17
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7/1216	17/8380	2.84	6.83e-03	2.74e-02	17
GO:0032770	GO:0032770	positive regulation of monooxygenase activity	7/1216	17/8380	2.84	6.83e-03	2.74e-02	17
GO:0060143	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	7/1216	17/8380	2.84	6.83e-03	2.74e-02	17
GO:0021782	GO:0021782	glial cell development	18/1216	68/8380	1.82	6.90e-03	2.77e-02	68
GO:1901570	GO:1901570	fatty acid derivative biosynthetic process	17/1216	63/8380	1.86	6.95e-03	2.78e-02	63
GO:1903900	GO:1903900	regulation of viral life cycle	17/1216	63/8380	1.86	6.95e-03	2.78e-02	63
GO:0043542	GO:0043542	endothelial cell migration	28/1216	121/8380	1.59	7.12e-03	2.85e-02	121
GO:1903901	GO:1903901	negative regulation of viral life cycle	12/1216	39/8380	2.12	7.31e-03	2.92e-02	39
GO:0051353	GO:0051353	positive regulation of oxidoreductase activity	10/1216	30/8380	2.30	7.55e-03	3.00e-02	30
GO:0008154	GO:0008154	actin polymerization or depolymerization	26/1216	111/8380	1.61	7.90e-03	3.13e-02	111
GO:0043902	GO:0043902	positive regulation of multi-organism process	19/1216	74/8380	1.77	7.94e-03	3.15e-02	74
GO:0120162	GO:0120162	positive regulation of cold-induced thermogenesis	17/1216	64/8380	1.83	8.21e-03	3.25e-02	64
GO:0032872	GO:0032872	regulation of stress-activated MAPK cascade	31/1216	139/8380	1.54	8.42e-03	3.30e-02	139
GO:0010955	GO:0010955	negative regulation of protein processing	9/1216	26/8380	2.39	8.45e-03	3.30e-02	26
GO:0046006	GO:0046006	regulation of activated T cell proliferation	9/1216	26/8380	2.39	8.45e-03	3.30e-02	26
GO:0070229	GO:0070229	negative regulation of lymphocyte apoptotic process	9/1216	26/8380	2.39	8.45e-03	3.30e-02	26
GO:1903318	GO:1903318	negative regulation of protein maturation	9/1216	26/8380	2.39	8.45e-03	3.30e-02	26
GO:0010508	GO:0010508	positive regulation of autophagy	11/1216	35/8380	2.17	8.46e-03	3.30e-02	35
GO:0030574	GO:0030574	collagen catabolic process	11/1216	35/8380	2.17	8.46e-03	3.30e-02	35
GO:0001780	GO:0001780	neutrophil homeostasis	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0002323	GO:0002323	natural killer cell activation involved in immune response	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0002864	GO:0002864	regulation of acute inflammatory response to antigenic stimulus	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0002923	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0007252	GO:0007252	I-kappaB phosphorylation	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0032930	GO:0032930	positive regulation of superoxide anion generation	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0033033	GO:0033033	negative regulation of myeloid cell apoptotic process	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0033089	GO:0033089	positive regulation of T cell differentiation in thymus	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0033631	GO:0033631	cell-cell adhesion mediated by integrin	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0035666	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0042362	GO:0042362	fat-soluble vitamin biosynthetic process	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0050862	GO:0050862	positive regulation of T cell receptor signaling pathway	5/1216	10/8380	3.45	8.52e-03	3.30e-02	10
GO:0006691	GO:0006691	leukotriene metabolic process	8/1216	22/8380	2.51	9.25e-03	3.58e-02	22
GO:0071260	GO:0071260	cellular response to mechanical stimulus	13/1216	45/8380	1.99	9.51e-03	3.67e-02	45
GO:0030500	GO:0030500	regulation of bone mineralization	14/1216	50/8380	1.93	9.73e-03	3.74e-02	50
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	6/1216	14/8380	2.95	9.75e-03	3.74e-02	14
GO:0002922	GO:0002922	positive regulation of humoral immune response	6/1216	14/8380	2.95	9.75e-03	3.74e-02	14
GO:0034104	GO:0034104	negative regulation of tissue remodeling	6/1216	14/8380	2.95	9.75e-03	3.74e-02	14
GO:0090195	GO:0090195	chemokine secretion	6/1216	14/8380	2.95	9.75e-03	3.74e-02	14
GO:0031532	GO:0031532	actin cytoskeleton reorganization	16/1216	60/8380	1.84	9.78e-03	3.74e-02	60
GO:0001516	GO:0001516	prostaglandin biosynthetic process	7/1216	18/8380	2.68	9.80e-03	3.74e-02	18
GO:0007040	GO:0007040	lysosome organization	7/1216	18/8380	2.68	9.80e-03	3.74e-02	18
GO:0046457	GO:0046457	prostanoid biosynthetic process	7/1216	18/8380	2.68	9.80e-03	3.74e-02	18
GO:0071349	GO:0071349	cellular response to interleukin-12	7/1216	18/8380	2.68	9.80e-03	3.74e-02	18
GO:0080171	GO:0080171	lytic vacuole organization	7/1216	18/8380	2.68	9.80e-03	3.74e-02	18
GO:0007200	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	20/1216	81/8380	1.70	1.03e-02	3.93e-02	81
GO:0001885	GO:0001885	endothelial cell development	11/1216	36/8380	2.11	1.06e-02	4.05e-02	36
GO:0030282	GO:0030282	bone mineralization	19/1216	76/8380	1.72	1.07e-02	4.07e-02	76
GO:0106106	GO:0106106	cold-induced thermogenesis	22/1216	92/8380	1.65	1.08e-02	4.12e-02	92
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	22/1216	92/8380	1.65	1.08e-02	4.12e-02	92
GO:0007520	GO:0007520	myoblast fusion	9/1216	27/8380	2.30	1.11e-02	4.20e-02	27
GO:2000379	GO:2000379	positive regulation of reactive oxygen species metabolic process	16/1216	61/8380	1.81	1.15e-02	4.37e-02	61
GO:0032091	GO:0032091	negative regulation of protein binding	15/1216	56/8380	1.85	1.17e-02	4.41e-02	56
GO:0043506	GO:0043506	regulation of JUN kinase activity	15/1216	56/8380	1.85	1.17e-02	4.41e-02	56

Factor 6 : 2 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0003341	GO:0003341	cilium movement	35/4283	42/8380	1.63	1.35e-05	0.00679	42
GO:0003351	GO:0003351	epithelial cilium movement	15/4283	15/8380	1.96	4.19e-05	0.01867	15

Factor 7 : 2 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0031929	GO:0031929	TOR signaling	29/3826	35/8380	1.81	6.40e-06	0.0156	35
GO:0043648	GO:0043648	dicarboxylic acid metabolic process	43/3826	60/8380	1.57	3.82e-05	0.0465	60

Factor 9 : 26 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0030316	GO:0030316	osteoclast differentiation	44/3603	60/8380	1.71	1.72e-06	0.00158	60
GO:0030041	GO:0030041	actin filament polymerization	64/3603	98/8380	1.52	6.31e-06	0.00321	98
GO:0070972	GO:0070972	protein localization to endoplasmic reticulum	24/3603	29/8380	1.92	1.29e-05	0.00455	29
GO:0030833	GO:0030833	regulation of actin filament polymerization	55/3603	85/8380	1.50	4.14e-05	0.00655	85
GO:0051651	GO:0051651	maintenance of location in cell	31/3603	42/8380	1.72	4.90e-05	0.00701	42
GO:0046686	GO:0046686	response to cadmium ion	25/3603	32/8380	1.82	5.43e-05	0.00718	32
GO:0045185	GO:0045185	maintenance of protein location	33/3603	46/8380	1.67	7.25e-05	0.00852	46
GO:0002548	GO:0002548	monocyte chemotaxis	38/3603	55/8380	1.61	7.91e-05	0.00907	55
GO:0050922	GO:0050922	negative regulation of chemotaxis	34/3603	48/8380	1.65	8.56e-05	0.00957	48
GO:0006929	GO:0006929	substrate-dependent cell migration	17/3603	20/8380	1.98	1.38e-04	0.01290	20
GO:0045047	GO:0045047	protein targeting to ER	17/3603	20/8380	1.98	1.38e-04	0.01290	20
GO:0006402	GO:0006402	mRNA catabolic process	45/3603	69/8380	1.52	1.55e-04	0.01379	69
GO:0035747	GO:0035747	natural killer cell chemotaxis	10/3603	10/8380	2.33	2.14e-04	0.01686	10
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	21/3603	27/8380	1.81	2.48e-04	0.01804	27
GO:0006613	GO:0006613	cotranslational protein targeting to membrane	16/3603	19/8380	1.96	2.76e-04	0.01948	19
GO:0006614	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	16/3603	19/8380	1.96	2.76e-04	0.01948	19
GO:0048247	GO:0048247	lymphocyte chemotaxis	35/3603	52/8380	1.57	3.36e-04	0.02232	52
GO:0006413	GO:0006413	translational initiation	26/3603	36/8380	1.68	3.60e-04	0.02358	36
GO:0007030	GO:0007030	Golgi organization	23/3603	31/8380	1.73	4.19e-04	0.02631	31
GO:0032507	GO:0032507	maintenance of protein location in cell	23/3603	31/8380	1.73	4.19e-04	0.02631	31
GO:0000956	GO:0000956	nuclear-transcribed mRNA catabolic process	27/3603	38/8380	1.65	4.27e-04	0.02645	38
GO:0072599	GO:0072599	establishment of protein localization to endoplasmic reticulum	17/3603	21/8380	1.88	4.34e-04	0.02646	21
GO:0072678	GO:0072678	T cell migration	32/3603	47/8380	1.58	4.39e-04	0.02646	47
GO:0007040	GO:0007040	lysosome organization	15/3603	18/8380	1.94	5.47e-04	0.03056	18
GO:0080171	GO:0080171	lytic vacuole organization	15/3603	18/8380	1.94	5.47e-04	0.03056	18
GO:0000184	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	18/3603	23/8380	1.82	6.19e-04	0.03380	23

Factor 10 : 75 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0006413	GO:0006413	translational initiation	28/2500	36/8380	2.61	3.62e-09	1.71e-05	36
GO:0006396	GO:0006396	RNA processing	87/2500	175/8380	1.67	1.99e-08	2.35e-05	175
GO:0019693	GO:0019693	ribose phosphate metabolic process	107/2500	227/8380	1.58	1.99e-08	2.35e-05	227
GO:0045047	GO:0045047	protein targeting to ER	18/2500	20/8380	3.02	3.30e-08	3.12e-05	20
GO:0070972	GO:0070972	protein localization to endoplasmic reticulum	23/2500	29/8380	2.66	4.95e-08	3.90e-05	29
GO:0009259	GO:0009259	ribonucleotide metabolic process	104/2500	223/8380	1.56	6.26e-08	4.23e-05	223
GO:0006613	GO:0006613	cotranslational protein targeting to membrane	17/2500	19/8380	3.00	1.00e-07	5.19e-05	19
GO:0006614	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	17/2500	19/8380	3.00	1.00e-07	5.19e-05	19
GO:0072599	GO:0072599	establishment of protein localization to endoplasmic reticulum	18/2500	21/8380	2.87	1.66e-07	6.49e-05	21
GO:0006163	GO:0006163	purine nucleotide metabolic process	107/2500	235/8380	1.53	1.87e-07	6.49e-05	235
GO:0009150	GO:0009150	purine ribonucleotide metabolic process	101/2500	219/8380	1.55	1.92e-07	6.49e-05	219
GO:0006732	GO:0006732	coenzyme metabolic process	89/2500	188/8380	1.59	2.44e-07	7.69e-05	188
GO:0033865	GO:0033865	nucleoside bisphosphate metabolic process	44/2500	77/8380	1.92	5.14e-07	1.35e-04	77
GO:0033875	GO:0033875	ribonucleoside bisphosphate metabolic process	44/2500	77/8380	1.92	5.14e-07	1.35e-04	77
GO:0034032	GO:0034032	purine nucleoside bisphosphate metabolic process	44/2500	77/8380	1.92	5.14e-07	1.35e-04	77
GO:0000184	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	18/2500	23/8380	2.62	2.18e-06	4.90e-04	23
GO:0034660	GO:0034660	ncRNA metabolic process	48/2500	92/8380	1.75	5.51e-06	1.13e-03	92
GO:0009123	GO:0009123	nucleoside monophosphate metabolic process	56/2500	113/8380	1.66	7.45e-06	1.47e-03	113
GO:0009161	GO:0009161	ribonucleoside monophosphate metabolic process	52/2500	104/8380	1.68	1.13e-05	1.98e-03	104
GO:0006605	GO:0006605	protein targeting	59/2500	124/8380	1.59	2.11e-05	3.41e-03	124
GO:0009167	GO:0009167	purine ribonucleoside monophosphate metabolic process	50/2500	101/8380	1.66	2.35e-05	3.58e-03	101
GO:0046390	GO:0046390	ribose phosphate biosynthetic process	58/2500	122/8380	1.59	2.54e-05	3.64e-03	122
GO:0009141	GO:0009141	nucleoside triphosphate metabolic process	54/2500	112/8380	1.62	2.93e-05	4.04e-03	112
GO:0006888	GO:0006888	ER to Golgi vesicle-mediated transport	32/2500	57/8380	1.88	2.99e-05	4.04e-03	57
GO:0009260	GO:0009260	ribonucleotide biosynthetic process	57/2500	120/8380	1.59	3.07e-05	4.04e-03	120
GO:0009126	GO:0009126	purine nucleoside monophosphate metabolic process	50/2500	102/8380	1.64	3.29e-05	4.09e-03	102
GO:0009199	GO:0009199	ribonucleoside triphosphate metabolic process	50/2500	102/8380	1.64	3.29e-05	4.09e-03	102
GO:0007005	GO:0007005	mitochondrion organization	65/2500	142/8380	1.53	3.82e-05	4.63e-03	142
GO:0010257	GO:0010257	NADH dehydrogenase complex assembly	10/2500	11/8380	3.05	4.43e-05	4.98e-03	11
GO:0032981	GO:0032981	mitochondrial respiratory chain complex I assembly	10/2500	11/8380	3.05	4.43e-05	4.98e-03	11
GO:0009144	GO:0009144	purine nucleoside triphosphate metabolic process	50/2500	103/8380	1.63	4.56e-05	5.02e-03	103
GO:0033108	GO:0033108	mitochondrial respiratory chain complex assembly	11/2500	13/8380	2.84	6.78e-05	7.08e-03	13
GO:0034470	GO:0034470	ncRNA processing	30/2500	54/8380	1.86	6.89e-05	7.08e-03	54
GO:0046034	GO:0046034	ATP metabolic process	44/2500	89/8380	1.66	7.44e-05	7.48e-03	89
GO:0022613	GO:0022613	ribonucleoprotein complex biogenesis	31/2500	57/8380	1.82	9.02e-05	8.86e-03	57
GO:0009205	GO:0009205	purine ribonucleoside triphosphate metabolic process	48/2500	100/8380	1.61	9.18e-05	8.86e-03	100
GO:0009152	GO:0009152	purine ribonucleotide biosynthetic process	54/2500	116/8380	1.56	9.73e-05	9.20e-03	116
GO:0006401	GO:0006401	RNA catabolic process	41/2500	83/8380	1.66	1.32e-04	1.20e-02	83
GO:0042274	GO:0042274	ribosomal small subunit biogenesis	9/2500	10/8380	3.02	1.36e-04	1.21e-02	10
GO:0098813	GO:0098813	nuclear chromosome segregation	52/2500	112/8380	1.56	1.42e-04	1.24e-02	112
GO:0072522	GO:0072522	purine-containing compound biosynthetic process	59/2500	131/8380	1.51	1.50e-04	1.29e-02	131
GO:0042254	GO:0042254	ribosome biogenesis	22/2500	37/8380	1.99	1.69e-04	1.39e-02	37
GO:0045333	GO:0045333	cellular respiration	25/2500	44/8380	1.90	1.70e-04	1.39e-02	44
GO:0006637	GO:0006637	acyl-CoA metabolic process	32/2500	61/8380	1.76	1.73e-04	1.39e-02	61
GO:0035383	GO:0035383	thioester metabolic process	32/2500	61/8380	1.76	1.73e-04	1.39e-02	61
GO:0006119	GO:0006119	oxidative phosphorylation	17/2500	26/8380	2.19	1.86e-04	1.39e-02	26
GO:0022904	GO:0022904	respiratory electron transport chain	17/2500	26/8380	2.19	1.86e-04	1.39e-02	26
GO:0016072	GO:0016072	rRNA metabolic process	21/2500	35/8380	2.01	1.98e-04	1.44e-02	35
GO:0006900	GO:0006900	vesicle budding from membrane	16/2500	24/8380	2.23	2.06e-04	1.48e-02	24
GO:0009124	GO:0009124	nucleoside monophosphate biosynthetic process	33/2500	64/8380	1.73	2.11e-04	1.49e-02	64
GO:1990542	GO:1990542	mitochondrial transmembrane transport	15/2500	22/8380	2.29	2.25e-04	1.56e-02	22
GO:0042773	GO:0042773	ATP synthesis coupled electron transport	13/2500	18/8380	2.42	2.49e-04	1.68e-02	18
GO:0042775	GO:0042775	mitochondrial ATP synthesis coupled electron transport	13/2500	18/8380	2.42	2.49e-04	1.68e-02	18
GO:0000956	GO:0000956	nuclear-transcribed mRNA catabolic process	22/2500	38/8380	1.94	2.89e-04	1.89e-02	38
GO:0006364	GO:0006364	rRNA processing	17/2500	27/8380	2.11	3.63e-04	2.32e-02	27
GO:0009201	GO:0009201	ribonucleoside triphosphate biosynthetic process	30/2500	58/8380	1.73	3.78e-04	2.38e-02	58
GO:0009156	GO:0009156	ribonucleoside monophosphate biosynthetic process	31/2500	61/8380	1.70	4.54e-04	2.78e-02	61
GO:0007062	GO:0007062	sister chromatid cohesion	15/2500	23/8380	2.19	4.69e-04	2.84e-02	23
GO:0009142	GO:0009142	nucleoside triphosphate biosynthetic process	32/2500	64/8380	1.68	5.36e-04	3.15e-02	64
GO:0070125	GO:0070125	mitochondrial translational elongation	9/2500	11/8380	2.74	5.47e-04	3.15e-02	11
GO:0070126	GO:0070126	mitochondrial translational termination	9/2500	11/8380	2.74	5.47e-04	3.15e-02	11
GO:0009108	GO:0009108	coenzyme biosynthetic process	49/2500	109/8380	1.51	5.55e-04	3.16e-02	109
GO:0006414	GO:0006414	translational elongation	12/2500	17/8380	2.37	6.12e-04	3.44e-02	17
GO:0033866	GO:0033866	nucleoside bisphosphate biosynthetic process	20/2500	35/8380	1.92	6.86e-04	3.72e-02	35
GO:0034030	GO:0034030	ribonucleoside bisphosphate biosynthetic process	20/2500	35/8380	1.92	6.86e-04	3.72e-02	35
GO:0034033	GO:0034033	purine nucleoside bisphosphate biosynthetic process	20/2500	35/8380	1.92	6.86e-04	3.72e-02	35
GO:1902600	GO:1902600	proton transmembrane transport	34/2500	70/8380	1.63	7.15e-04	3.84e-02	70
GO:0016125	GO:0016125	sterol metabolic process	43/2500	94/8380	1.53	7.61e-04	4.04e-02	94
GO:0008203	GO:0008203	cholesterol metabolic process	38/2500	81/8380	1.57	8.37e-04	4.40e-02	81
GO:0090502	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	15/2500	24/8380	2.10	9.07e-04	4.55e-02	24
GO:0015980	GO:0015980	energy derivation by oxidation of organic compounds	42/2500	92/8380	1.53	9.18e-04	4.55e-02	92
GO:1902652	GO:1902652	secondary alcohol metabolic process	39/2500	84/8380	1.56	9.25e-04	4.55e-02	84
GO:0009127	GO:0009127	purine nucleoside monophosphate biosynthetic process	29/2500	58/8380	1.68	9.63e-04	4.60e-02	58
GO:0009168	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	29/2500	58/8380	1.68	9.63e-04	4.60e-02	58
GO:0009116	GO:0009116	nucleoside metabolic process	27/2500	53/8380	1.71	9.91e-04	4.68e-02	53

Factor 11 : 12 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0070268	GO:0070268	cornification	71/3356	95/8380	1.87	5.40e-12	2.64e-08	95
GO:0031424	GO:0031424	keratinization	80/3356	113/8380	1.77	2.71e-11	6.64e-08	113
GO:0030216	GO:0030216	keratinocyte differentiation	105/3356	161/8380	1.63	6.72e-11	1.10e-07	161
GO:0009913	GO:0009913	epidermal cell differentiation	118/3356	193/8380	1.53	1.82e-09	1.78e-06	193
GO:0006613	GO:0006613	cotranslational protein targeting to membrane	19/3356	19/8380	2.50	2.73e-08	1.67e-05	19
GO:0006614	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	19/3356	19/8380	2.50	2.73e-08	1.67e-05	19
GO:0072599	GO:0072599	establishment of protein localization to endoplasmic reticulum	20/3356	21/8380	2.38	1.42e-07	7.71e-05	21
GO:0045047	GO:0045047	protein targeting to ER	19/3356	20/8380	2.37	3.39e-07	1.66e-04	20
GO:0000184	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	20/3356	23/8380	2.17	4.60e-06	1.88e-03	23
GO:0070972	GO:0070972	protein localization to endoplasmic reticulum	23/3356	29/8380	1.98	1.84e-05	6.95e-03	29
GO:0052697	GO:0052697	xenobiotic glucuronidation	11/3356	11/8380	2.50	4.21e-05	1.47e-02	11
GO:0009812	GO:0009812	flavonoid metabolic process	12/3356	13/8380	2.30	1.38e-04	4.51e-02	13

Factor 12 : 59 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0007018	GO:0007018	microtubule-based movement	81/2594	125/8380	2.09	4.54e-15	2.13e-11	125
GO:0007017	GO:0007017	microtubule-based process	170/2594	335/8380	1.64	1.08e-14	2.53e-11	335
GO:0044782	GO:0044782	cilium organization	91/2594	151/8380	1.95	6.25e-14	9.76e-11	151
GO:0060271	GO:0060271	cilium assembly	85/2594	140/8380	1.96	2.35e-13	2.71e-10	140
GO:0001578	GO:0001578	microtubule bundle formation	45/2594	58/8380	2.51	2.89e-13	2.71e-10	58
GO:0120031	GO:0120031	plasma membrane bounded cell projection assembly	131/2594	251/8380	1.69	1.01e-12	7.09e-10	251
GO:0035082	GO:0035082	axoneme assembly	36/2594	43/8380	2.70	1.06e-12	7.09e-10	43
GO:0003341	GO:0003341	cilium movement	35/2594	42/8380	2.69	2.90e-12	1.70e-09	42
GO:0030031	GO:0030031	cell projection assembly	134/2594	262/8380	1.65	3.84e-12	2.00e-09	262
GO:0007269	GO:0007269	neurotransmitter secretion	69/2594	117/8380	1.91	2.73e-10	1.16e-07	117
GO:0099643	GO:0099643	signal release from synapse	69/2594	117/8380	1.91	2.73e-10	1.16e-07	117
GO:0099504	GO:0099504	synaptic vesicle cycle	72/2594	124/8380	1.88	3.00e-10	1.17e-07	124
GO:0099003	GO:0099003	vesicle-mediated transport in synapse	67/2594	118/8380	1.83	4.50e-09	1.41e-06	118
GO:0006836	GO:0006836	neurotransmitter transport	96/2594	189/8380	1.64	7.26e-09	1.89e-06	189
GO:0001505	GO:0001505	regulation of neurotransmitter levels	115/2594	241/8380	1.54	2.47e-08	6.10e-06	241
GO:0051648	GO:0051648	vesicle localization	77/2594	146/8380	1.70	2.82e-08	6.61e-06	146
GO:0070286	GO:0070286	axonemal dynein complex assembly	20/2594	23/8380	2.81	3.88e-08	8.35e-06	23
GO:0017156	GO:0017156	calcium ion regulated exocytosis	59/2594	104/8380	1.83	3.92e-08	8.35e-06	104
GO:0017158	GO:0017158	regulation of calcium ion-dependent exocytosis	46/2594	75/8380	1.98	4.90e-08	9.99e-06	75
GO:0097479	GO:0097479	synaptic vesicle localization	59/2594	105/8380	1.82	6.27e-08	1.22e-05	105
GO:0051650	GO:0051650	establishment of vesicle localization	70/2594	134/8380	1.69	1.96e-07	3.26e-05	134
GO:0048489	GO:0048489	synaptic vesicle transport	54/2594	96/8380	1.82	2.16e-07	3.26e-05	96
GO:0097480	GO:0097480	establishment of synaptic vesicle localization	54/2594	96/8380	1.82	2.16e-07	3.26e-05	96
GO:0098693	GO:0098693	regulation of synaptic vesicle cycle	44/2594	74/8380	1.92	3.42e-07	5.00e-05	74
GO:0016079	GO:0016079	synaptic vesicle exocytosis	48/2594	84/8380	1.85	5.37e-07	7.40e-05	84
GO:0046928	GO:0046928	regulation of neurotransmitter secretion	44/2594	75/8380	1.90	5.81e-07	7.77e-05	75
GO:0008306	GO:0008306	associative learning	31/2594	48/8380	2.09	1.55e-06	1.91e-04	48
GO:0007632	GO:0007632	visual behavior	22/2594	30/8380	2.37	2.13e-06	2.56e-04	30
GO:0048167	GO:0048167	regulation of synaptic plasticity	61/2594	119/8380	1.66	2.70e-06	3.16e-04	119
GO:0007368	GO:0007368	determination of left/right symmetry	38/2594	65/8380	1.89	3.83e-06	4.37e-04	65
GO:0008542	GO:0008542	visual learning	20/2594	27/8380	2.39	4.89e-06	5.45e-04	27
GO:0007612	GO:0007612	learning	51/2594	97/8380	1.70	6.89e-06	7.50e-04	97
GO:0009855	GO:0009855	determination of bilateral symmetry	40/2594	71/8380	1.82	7.59e-06	8.08e-04	71
GO:0001539	GO:0001539	cilium or flagellum-dependent cell motility	17/2594	22/8380	2.50	1.01e-05	9.99e-04	22
GO:0045956	GO:0045956	positive regulation of calcium ion-dependent exocytosis	17/2594	22/8380	2.50	1.01e-05	9.99e-04	22
GO:0060285	GO:0060285	cilium-dependent cell motility	17/2594	22/8380	2.50	1.01e-05	9.99e-04	22
GO:0017157	GO:0017157	regulation of exocytosis	65/2594	133/8380	1.58	1.02e-05	9.99e-04	133
GO:0009799	GO:0009799	specification of symmetry	40/2594	72/8380	1.79	1.20e-05	1.12e-03	72
GO:0036158	GO:0036158	outer dynein arm assembly	11/2594	12/8380	2.96	2.12e-05	1.91e-03	12
GO:0051588	GO:0051588	regulation of neurotransmitter transport	50/2594	99/8380	1.63	3.52e-05	3.11e-03	99
GO:0140029	GO:0140029	exocytic process	28/2594	47/8380	1.92	4.48e-05	3.75e-03	47
GO:2000300	GO:2000300	regulation of synaptic vesicle exocytosis	31/2594	54/8380	1.85	4.86e-05	3.89e-03	54
GO:1903305	GO:1903305	regulation of regulated secretory pathway	52/2594	105/8380	1.60	4.90e-05	3.89e-03	105
GO:1902803	GO:1902803	regulation of synaptic vesicle transport	31/2594	57/8380	1.76	1.92e-04	1.30e-02	57
GO:0030534	GO:0030534	adult behavior	45/2594	93/8380	1.56	3.04e-04	1.97e-02	93
GO:0051966	GO:0051966	regulation of synaptic transmission, glutamatergic	28/2594	51/8380	1.77	3.15e-04	2.02e-02	51
GO:0060632	GO:0060632	regulation of microtubule-based movement	12/2594	16/8380	2.42	3.64e-04	2.24e-02	16
GO:0010970	GO:0010970	transport along microtubule	27/2594	49/8380	1.78	3.72e-04	2.24e-02	49
GO:0099111	GO:0099111	microtubule-based transport	27/2594	49/8380	1.78	3.72e-04	2.24e-02	49
GO:0009060	GO:0009060	aerobic respiration	13/2594	18/8380	2.33	3.75e-04	2.24e-02	18
GO:0003143	GO:0003143	embryonic heart tube morphogenesis	24/2594	42/8380	1.85	3.78e-04	2.24e-02	42
GO:0045921	GO:0045921	positive regulation of exocytosis	29/2594	54/8380	1.73	4.08e-04	2.39e-02	54
GO:0061371	GO:0061371	determination of heart left/right asymmetry	23/2594	40/8380	1.86	4.41e-04	2.55e-02	40
GO:0035418	GO:0035418	protein localization to synapse	23/2594	41/8380	1.81	7.13e-04	3.93e-02	41
GO:0036159	GO:0036159	inner dynein arm assembly	9/2594	11/8380	2.64	7.42e-04	4.00e-02	11
GO:0042271	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	9/2594	11/8380	2.64	7.42e-04	4.00e-02	11
GO:0035050	GO:0035050	embryonic heart tube development	25/2594	46/8380	1.76	8.00e-04	4.26e-02	46
GO:0003351	GO:0003351	epithelial cilium movement	11/2594	15/8380	2.37	8.95e-04	4.61e-02	15
GO:0030705	GO:0030705	cytoskeleton-dependent intracellular transport	29/2594	56/8380	1.67	8.97e-04	4.61e-02	56

Factor 13 : 1 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0007156	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	88/3070	149/8380	1.61	1.7e-08	8.3e-05	149

Factor 14 : 760 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001944	GO:0001944	vasculature development	175/1669	465/8380	1.89	5.70e-20	1.97e-16	465
GO:0001568	GO:0001568	blood vessel development	169/1669	448/8380	1.89	2.01e-19	3.13e-16	448
GO:0072358	GO:0072358	cardiovascular system development	175/1669	471/8380	1.87	2.72e-19	3.13e-16	471
GO:0048514	GO:0048514	blood vessel morphogenesis	154/1669	404/8380	1.91	3.02e-18	2.60e-15	404
GO:0001525	GO:0001525	angiogenesis	134/1669	342/8380	1.97	3.91e-17	2.70e-14	342
GO:0045765	GO:0045765	regulation of angiogenesis	84/1669	191/8380	2.21	1.91e-14	1.10e-11	191
GO:1901342	GO:1901342	regulation of vasculature development	90/1669	214/8380	2.11	5.70e-14	2.81e-11	214
GO:0050727	GO:0050727	regulation of inflammatory response	96/1669	251/8380	1.92	7.37e-12	3.18e-09	251
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	150/1669	465/8380	1.62	6.59e-11	2.42e-08	465
GO:0051051	GO:0051051	negative regulation of transport	104/1669	289/8380	1.81	7.01e-11	2.42e-08	289
GO:0001935	GO:0001935	endothelial cell proliferation	46/1669	94/8380	2.46	2.19e-10	6.71e-08	94
GO:0032496	GO:0032496	response to lipopolysaccharide	82/1669	214/8380	1.92	2.33e-10	6.71e-08	214
GO:0019216	GO:0019216	regulation of lipid metabolic process	84/1669	222/8380	1.90	2.94e-10	7.81e-08	222
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	42/1669	83/8380	2.54	3.53e-10	8.69e-08	83
GO:0001667	GO:0001667	ameboidal-type cell migration	88/1669	239/8380	1.85	5.64e-10	1.30e-07	239
GO:0071363	GO:0071363	cellular response to growth factor stimulus	128/1669	391/8380	1.64	6.36e-10	1.37e-07	391
GO:0070848	GO:0070848	response to growth factor	132/1669	410/8380	1.62	1.15e-09	2.25e-07	410
GO:0000302	GO:0000302	response to reactive oxygen species	52/1669	117/8380	2.23	1.22e-09	2.25e-07	117
GO:0002237	GO:0002237	response to molecule of bacterial origin	83/1669	224/8380	1.86	1.24e-09	2.25e-07	224
GO:0040017	GO:0040017	positive regulation of locomotion	116/1669	349/8380	1.67	1.54e-09	2.66e-07	349
GO:0030335	GO:0030335	positive regulation of cell migration	108/1669	320/8380	1.69	2.20e-09	3.62e-07	320
GO:0010243	GO:0010243	response to organonitrogen compound	151/1669	493/8380	1.54	3.60e-09	5.64e-07	493
GO:0030155	GO:0030155	regulation of cell adhesion	142/1669	458/8380	1.56	4.51e-09	6.65e-07	458
GO:1904018	GO:1904018	positive regulation of vasculature development	53/1669	124/8380	2.15	4.62e-09	6.65e-07	124
GO:0043542	GO:0043542	endothelial cell migration	52/1669	121/8380	2.16	5.15e-09	7.09e-07	121
GO:0008285	GO:0008285	negative regulation of cell proliferation	135/1669	431/8380	1.57	5.43e-09	7.09e-07	431
GO:0010631	GO:0010631	epithelial cell migration	66/1669	169/8380	1.96	5.55e-09	7.09e-07	169
GO:2000147	GO:2000147	positive regulation of cell motility	110/1669	333/8380	1.66	6.15e-09	7.58e-07	333
GO:0043062	GO:0043062	extracellular structure organization	108/1669	326/8380	1.66	7.10e-09	8.44e-07	326
GO:0090132	GO:0090132	epithelium migration	66/1669	170/8380	1.95	7.34e-09	8.44e-07	170
GO:0003013	GO:0003013	circulatory system process	116/1669	360/8380	1.62	1.17e-08	1.30e-06	360
GO:0050673	GO:0050673	epithelial cell proliferation	89/1669	256/8380	1.75	1.20e-08	1.30e-06	256
GO:0090130	GO:0090130	tissue migration	67/1669	176/8380	1.91	1.43e-08	1.50e-06	176
GO:0050678	GO:0050678	regulation of epithelial cell proliferation	79/1669	220/8380	1.80	1.60e-08	1.61e-06	220
GO:0008015	GO:0008015	blood circulation	114/1669	354/8380	1.62	1.64e-08	1.61e-06	354
GO:0019935	GO:0019935	cyclic-nucleotide-mediated signaling	62/1669	159/8380	1.96	1.73e-08	1.65e-06	159
GO:0002040	GO:0002040	sprouting angiogenesis	37/1669	77/8380	2.41	2.39e-08	2.23e-06	77
GO:0010594	GO:0010594	regulation of endothelial cell migration	41/1669	90/8380	2.29	2.91e-08	2.65e-06	90
GO:0050900	GO:0050900	leukocyte migration	104/1669	319/8380	1.64	3.51e-08	3.10e-06	319
GO:0016525	GO:0016525	negative regulation of angiogenesis	34/1669	69/8380	2.47	4.00e-08	3.45e-06	69
GO:0019932	GO:0019932	second-messenger-mediated signaling	104/1669	320/8380	1.63	4.20e-08	3.54e-06	320
GO:0051272	GO:0051272	positive regulation of cellular component movement	110/1669	344/8380	1.61	4.51e-08	3.70e-06	344
GO:0002790	GO:0002790	peptide secretion	119/1669	380/8380	1.57	4.65e-08	3.74e-06	380
GO:0071346	GO:0071346	cellular response to interferon-gamma	50/1669	121/8380	2.07	4.77e-08	3.74e-06	121
GO:1901652	GO:1901652	response to peptide	88/1669	260/8380	1.70	6.07e-08	4.65e-06	260
GO:0045834	GO:0045834	positive regulation of lipid metabolic process	41/1669	92/8380	2.24	6.28e-08	4.71e-06	92
GO:0006898	GO:0006898	receptor-mediated endocytosis	68/1669	186/8380	1.84	7.25e-08	5.21e-06	186
GO:0050729	GO:0050729	positive regulation of inflammatory response	43/1669	99/8380	2.18	7.51e-08	5.29e-06	99
GO:0009636	GO:0009636	response to toxic substance	100/1669	308/8380	1.63	8.15e-08	5.63e-06	308
GO:0042180	GO:0042180	cellular ketone metabolic process	45/1669	106/8380	2.13	8.59e-08	5.80e-06	106
GO:0010469	GO:0010469	regulation of signaling receptor activity	122/1669	396/8380	1.55	8.74e-08	5.80e-06	396
GO:0010565	GO:0010565	regulation of cellular ketone metabolic process	35/1669	74/8380	2.37	9.42e-08	6.03e-06	74
GO:0019933	GO:0019933	cAMP-mediated signaling	54/1669	137/8380	1.98	9.44e-08	6.03e-06	137
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	34/1669	71/8380	2.40	9.81e-08	6.04e-06	71
GO:0046677	GO:0046677	response to antibiotic	66/1669	180/8380	1.84	9.92e-08	6.04e-06	180
GO:0062012	GO:0062012	regulation of small molecule metabolic process	69/1669	191/8380	1.81	9.98e-08	6.04e-06	191
GO:0001101	GO:0001101	response to acid chemical	77/1669	221/8380	1.75	1.06e-07	6.20e-06	221
GO:0045766	GO:0045766	positive regulation of angiogenesis	46/1669	110/8380	2.10	1.07e-07	6.20e-06	110
GO:0030198	GO:0030198	extracellular matrix organization	95/1669	290/8380	1.64	1.08e-07	6.20e-06	290
GO:0060326	GO:0060326	cell chemotaxis	78/1669	225/8380	1.74	1.12e-07	6.31e-06	225
GO:0050663	GO:0050663	cytokine secretion	57/1669	149/8380	1.92	1.41e-07	7.80e-06	149
GO:0010632	GO:0010632	regulation of epithelial cell migration	51/1669	128/8380	2.00	1.43e-07	7.80e-06	128
GO:0034341	GO:0034341	response to interferon-gamma	53/1669	135/8380	1.97	1.45e-07	7.80e-06	135
GO:0071674	GO:0071674	mononuclear cell migration	33/1669	69/8380	2.40	1.57e-07	8.34e-06	69
GO:0006897	GO:0006897	endocytosis	121/1669	396/8380	1.53	1.64e-07	8.55e-06	396
GO:0070555	GO:0070555	response to interleukin-1	42/1669	98/8380	2.15	1.68e-07	8.59e-06	98
GO:0006979	GO:0006979	response to oxidative stress	78/1669	227/8380	1.73	1.70e-07	8.59e-06	227
GO:0071396	GO:0071396	cellular response to lipid	113/1669	364/8380	1.56	1.72e-07	8.59e-06	364
GO:0006874	GO:0006874	cellular calcium ion homeostasis	100/1669	313/8380	1.60	1.97e-07	9.71e-06	313
GO:0003158	GO:0003158	endothelium development	34/1669	73/8380	2.34	2.29e-07	1.11e-05	73
GO:0007187	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	68/1669	191/8380	1.79	2.34e-07	1.12e-05	191
GO:0019217	GO:0019217	regulation of fatty acid metabolic process	26/1669	49/8380	2.66	2.43e-07	1.14e-05	49
GO:0061061	GO:0061061	muscle structure development	123/1669	407/8380	1.52	2.51e-07	1.16e-05	407
GO:0070542	GO:0070542	response to fatty acid	30/1669	61/8380	2.47	2.65e-07	1.20e-05	61
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	35/1669	77/8380	2.28	3.20e-07	1.41e-05	77
GO:0001937	GO:0001937	negative regulation of endothelial cell proliferation	16/1669	23/8380	3.49	3.37e-07	1.47e-05	23
GO:0051048	GO:0051048	negative regulation of secretion	56/1669	149/8380	1.89	3.61e-07	1.55e-05	149
GO:0009306	GO:0009306	protein secretion	109/1669	353/8380	1.55	3.85e-07	1.60e-05	353
GO:0043534	GO:0043534	blood vessel endothelial cell migration	32/1669	68/8380	2.36	3.85e-07	1.60e-05	68
GO:0036293	GO:0036293	response to decreased oxygen levels	68/1669	194/8380	1.76	4.57e-07	1.88e-05	194
GO:0009617	GO:0009617	response to bacterium	119/1669	395/8380	1.51	4.77e-07	1.94e-05	395
GO:0062013	GO:0062013	positive regulation of small molecule metabolic process	38/1669	88/8380	2.17	5.12e-07	2.05e-05	88
GO:0044057	GO:0044057	regulation of system process	120/1669	400/8380	1.51	5.44e-07	2.16e-05	400
GO:0097529	GO:0097529	myeloid leukocyte migration	58/1669	158/8380	1.84	5.64e-07	2.21e-05	158
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	23/1669	42/8380	2.75	5.74e-07	2.22e-05	42
GO:0001659	GO:0001659	temperature homeostasis	45/1669	112/8380	2.02	5.81e-07	2.23e-05	112
GO:0055074	GO:0055074	calcium ion homeostasis	101/1669	324/8380	1.57	6.36e-07	2.41e-05	324
GO:0070482	GO:0070482	response to oxygen levels	70/1669	204/8380	1.72	7.74e-07	2.87e-05	204
GO:0002042	GO:0002042	cell migration involved in sprouting angiogenesis	21/1669	37/8380	2.85	8.04e-07	2.93e-05	37
GO:0032103	GO:0032103	positive regulation of response to external stimulus	71/1669	208/8380	1.71	8.08e-07	2.93e-05	208
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	77/1669	231/8380	1.67	8.15e-07	2.93e-05	231
GO:1990868	GO:1990868	response to chemokine	36/1669	83/8380	2.18	8.93e-07	3.14e-05	83
GO:1990869	GO:1990869	cellular response to chemokine	36/1669	83/8380	2.18	8.93e-07	3.14e-05	83
GO:0003018	GO:0003018	vascular process in circulatory system	46/1669	117/8380	1.97	9.11e-07	3.17e-05	117
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	84/1669	259/8380	1.63	9.49e-07	3.27e-05	259
GO:0007517	GO:0007517	muscle organ development	86/1669	267/8380	1.62	9.75e-07	3.33e-05	267
GO:0001501	GO:0001501	skeletal system development	107/1669	351/8380	1.53	9.86e-07	3.34e-05	351
GO:0033002	GO:0033002	muscle cell proliferation	51/1669	135/8380	1.90	9.96e-07	3.34e-05	135
GO:0071229	GO:0071229	cellular response to acid chemical	54/1669	146/8380	1.86	1.05e-06	3.45e-05	146
GO:0097305	GO:0097305	response to alcohol	54/1669	146/8380	1.86	1.05e-06	3.45e-05	146
GO:0009612	GO:0009612	response to mechanical stimulus	52/1669	139/8380	1.88	1.11e-06	3.61e-05	139
GO:0007178	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	69/1669	202/8380	1.72	1.12e-06	3.61e-05	202
GO:0010596	GO:0010596	negative regulation of endothelial cell migration	17/1669	27/8380	3.16	1.23e-06	3.94e-05	27
GO:0050679	GO:0050679	positive regulation of epithelial cell proliferation	51/1669	136/8380	1.88	1.29e-06	4.09e-05	136
GO:0003007	GO:0003007	heart morphogenesis	62/1669	177/8380	1.76	1.50e-06	4.71e-05	177
GO:0007188	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	60/1669	170/8380	1.77	1.66e-06	5.17e-05	170
GO:0001666	GO:0001666	response to hypoxia	65/1669	189/8380	1.73	1.75e-06	5.39e-05	189
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	25/1669	50/8380	2.51	1.78e-06	5.44e-05	50
GO:0043434	GO:0043434	response to peptide hormone	72/1669	216/8380	1.67	1.85e-06	5.61e-05	216
GO:1903531	GO:1903531	negative regulation of secretion by cell	48/1669	127/8380	1.90	2.03e-06	6.10e-05	127
GO:0072503	GO:0072503	cellular divalent inorganic cation homeostasis	102/1669	336/8380	1.52	2.19e-06	6.52e-05	336
GO:0046320	GO:0046320	regulation of fatty acid oxidation	13/1669	18/8380	3.63	2.32e-06	6.86e-05	18
GO:0031960	GO:0031960	response to corticosteroid	45/1669	117/8380	1.93	2.43e-06	7.10e-05	117
GO:0051271	GO:0051271	negative regulation of cellular component movement	69/1669	206/8380	1.68	2.49e-06	7.23e-05	206
GO:0007507	GO:0007507	heart development	101/1669	333/8380	1.52	2.57e-06	7.33e-05	333
GO:0045444	GO:0045444	fat cell differentiation	51/1669	139/8380	1.84	2.74e-06	7.74e-05	139
GO:1901654	GO:1901654	response to ketone	47/1669	125/8380	1.89	3.06e-06	8.60e-05	125
GO:1901343	GO:1901343	negative regulation of vasculature development	34/1669	80/8380	2.13	3.13e-06	8.70e-05	80
GO:1990845	GO:1990845	adaptive thermogenesis	39/1669	97/8380	2.02	3.19e-06	8.75e-05	97
GO:0030336	GO:0030336	negative regulation of cell migration	60/1669	173/8380	1.74	3.19e-06	8.75e-05	173
GO:0072507	GO:0072507	divalent inorganic cation homeostasis	105/1669	351/8380	1.50	3.28e-06	8.91e-05	351
GO:0034614	GO:0034614	cellular response to reactive oxygen species	33/1669	77/8380	2.15	3.49e-06	9.40e-05	77
GO:0002791	GO:0002791	regulation of peptide secretion	95/1669	311/8380	1.53	3.66e-06	9.80e-05	311
GO:0045785	GO:0045785	positive regulation of cell adhesion	89/1669	287/8380	1.56	3.77e-06	1.00e-04	287
GO:0090049	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	16/1669	26/8380	3.09	3.95e-06	1.04e-04	26
GO:0002548	GO:0002548	monocyte chemotaxis	26/1669	55/8380	2.37	4.26e-06	1.11e-04	55
GO:0007189	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	41/1669	105/8380	1.96	4.33e-06	1.12e-04	105
GO:0001570	GO:0001570	vasculogenesis	25/1669	52/8380	2.41	4.44e-06	1.14e-04	52
GO:1903532	GO:1903532	positive regulation of secretion by cell	80/1669	254/8380	1.58	6.10e-06	1.53e-04	254
GO:0034308	GO:0034308	primary alcohol metabolic process	26/1669	56/8380	2.33	6.46e-06	1.60e-04	56
GO:0042542	GO:0042542	response to hydrogen peroxide	30/1669	69/8380	2.18	6.77e-06	1.67e-04	69
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	74/1669	231/8380	1.61	6.93e-06	1.70e-04	231
GO:0040013	GO:0040013	negative regulation of locomotion	68/1669	208/8380	1.64	7.57e-06	1.83e-04	208
GO:2000146	GO:2000146	negative regulation of cell motility	61/1669	181/8380	1.69	7.59e-06	1.83e-04	181
GO:0045446	GO:0045446	endothelial cell differentiation	28/1669	63/8380	2.23	8.19e-06	1.96e-04	63
GO:0090092	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	50/1669	140/8380	1.79	8.25e-06	1.96e-04	140
GO:0071347	GO:0071347	cellular response to interleukin-1	34/1669	83/8380	2.06	8.32e-06	1.96e-04	83
GO:0070371	GO:0070371	ERK1 and ERK2 cascade	76/1669	240/8380	1.59	8.36e-06	1.96e-04	240
GO:0048659	GO:0048659	smooth muscle cell proliferation	38/1669	97/8380	1.97	8.79e-06	2.05e-04	97
GO:0071417	GO:0071417	cellular response to organonitrogen compound	92/1669	305/8380	1.51	9.23e-06	2.14e-04	305
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	35/1669	87/8380	2.02	9.93e-06	2.28e-04	87
GO:0035150	GO:0035150	regulation of tube size	39/1669	101/8380	1.94	1.01e-05	2.29e-04	101
GO:0050880	GO:0050880	regulation of blood vessel size	39/1669	101/8380	1.94	1.01e-05	2.29e-04	101
GO:0003205	GO:0003205	cardiac chamber development	44/1669	119/8380	1.86	1.04e-05	2.34e-04	119
GO:0014068	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	24/1669	51/8380	2.36	1.09e-05	2.42e-04	51
GO:0042698	GO:0042698	ovulation cycle	24/1669	51/8380	2.36	1.09e-05	2.42e-04	51
GO:0030595	GO:0030595	leukocyte chemotaxis	58/1669	172/8380	1.69	1.24e-05	2.71e-04	172
GO:0061384	GO:0061384	heart trabecula morphogenesis	15/1669	25/8380	3.01	1.24e-05	2.71e-04	25
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	67/1669	207/8380	1.63	1.28e-05	2.78e-04	207
GO:0070374	GO:0070374	positive regulation of ERK1 and ERK2 cascade	60/1669	180/8380	1.67	1.32e-05	2.85e-04	180
GO:0051047	GO:0051047	positive regulation of secretion	84/1669	275/8380	1.53	1.34e-05	2.86e-04	275
GO:0034612	GO:0034612	response to tumor necrosis factor	55/1669	161/8380	1.72	1.35e-05	2.86e-04	161
GO:0070372	GO:0070372	regulation of ERK1 and ERK2 cascade	72/1669	227/8380	1.59	1.35e-05	2.86e-04	227
GO:0007162	GO:0007162	negative regulation of cell adhesion	58/1669	173/8380	1.68	1.51e-05	3.11e-04	173
GO:0051591	GO:0051591	response to cAMP	29/1669	68/8380	2.14	1.51e-05	3.11e-04	68
GO:0106106	GO:0106106	cold-induced thermogenesis	36/1669	92/8380	1.96	1.55e-05	3.15e-04	92
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	36/1669	92/8380	1.96	1.55e-05	3.15e-04	92
GO:0050707	GO:0050707	regulation of cytokine secretion	46/1669	128/8380	1.80	1.56e-05	3.15e-04	128
GO:0050867	GO:0050867	positive regulation of cell activation	70/1669	220/8380	1.60	1.58e-05	3.17e-04	220
GO:0001701	GO:0001701	in utero embryonic development	54/1669	158/8380	1.72	1.59e-05	3.17e-04	158
GO:2001057	GO:2001057	reactive nitrogen species metabolic process	24/1669	52/8380	2.32	1.65e-05	3.25e-04	52
GO:0048511	GO:0048511	rhythmic process	55/1669	162/8380	1.70	1.66e-05	3.25e-04	162
GO:0072593	GO:0072593	reactive oxygen species metabolic process	55/1669	162/8380	1.70	1.66e-05	3.25e-04	162
GO:0048660	GO:0048660	regulation of smooth muscle cell proliferation	37/1669	96/8380	1.94	1.77e-05	3.46e-04	96
GO:0002062	GO:0002062	chondrocyte differentiation	35/1669	89/8380	1.97	1.79e-05	3.47e-04	89
GO:0048545	GO:0048545	response to steroid hormone	73/1669	233/8380	1.57	1.89e-05	3.65e-04	233
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	19/1669	37/8380	2.58	1.91e-05	3.67e-04	37
GO:0003206	GO:0003206	cardiac chamber morphogenesis	38/1669	100/8380	1.91	2.00e-05	3.81e-04	100
GO:0043537	GO:0043537	negative regulation of blood vessel endothelial cell migration	12/1669	18/8380	3.35	2.10e-05	3.93e-04	18
GO:0051384	GO:0051384	response to glucocorticoid	39/1669	104/8380	1.88	2.24e-05	4.15e-04	104
GO:0042063	GO:0042063	gliogenesis	60/1669	183/8380	1.65	2.33e-05	4.25e-04	183
GO:0032102	GO:0032102	negative regulation of response to external stimulus	68/1669	215/8380	1.59	2.59e-05	4.67e-04	215
GO:0051224	GO:0051224	negative regulation of protein transport	38/1669	101/8380	1.89	2.60e-05	4.68e-04	101
GO:0046209	GO:0046209	nitric oxide metabolic process	23/1669	50/8380	2.31	2.64e-05	4.73e-04	50
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	34/1669	87/8380	1.96	2.74e-05	4.85e-04	87
GO:0050728	GO:0050728	negative regulation of inflammatory response	34/1669	87/8380	1.96	2.74e-05	4.85e-04	87
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	53/1669	157/8380	1.69	2.81e-05	4.94e-04	157
GO:0097237	GO:0097237	cellular response to toxic substance	45/1669	127/8380	1.78	2.89e-05	5.07e-04	127
GO:0002573	GO:0002573	myeloid leukocyte differentiation	46/1669	131/8380	1.76	3.08e-05	5.31e-04	131
GO:0008217	GO:0008217	regulation of blood pressure	46/1669	131/8380	1.76	3.08e-05	5.31e-04	131
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	51/1669	150/8380	1.71	3.18e-05	5.43e-04	150
GO:1904950	GO:1904950	negative regulation of establishment of protein localization	38/1669	102/8380	1.87	3.37e-05	5.70e-04	102
GO:0002685	GO:0002685	regulation of leukocyte migration	48/1669	139/8380	1.73	3.43e-05	5.77e-04	139
GO:0051235	GO:0051235	maintenance of location	62/1669	193/8380	1.61	3.45e-05	5.78e-04	193
GO:0046890	GO:0046890	regulation of lipid biosynthetic process	39/1669	106/8380	1.85	3.70e-05	6.14e-04	106
GO:0034694	GO:0034694	response to prostaglandin	14/1669	24/8380	2.93	3.80e-05	6.28e-04	24
GO:0046683	GO:0046683	response to organophosphorus	35/1669	92/8380	1.91	4.09e-05	6.73e-04	92
GO:0006809	GO:0006809	nitric oxide biosynthetic process	22/1669	48/8380	2.30	4.23e-05	6.89e-04	48
GO:0048015	GO:0048015	phosphatidylinositol-mediated signaling	38/1669	103/8380	1.85	4.33e-05	6.98e-04	103
GO:0097755	GO:0097755	positive regulation of blood vessel diameter	21/1669	45/8380	2.34	4.52e-05	7.26e-04	45
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	28/1669	68/8380	2.07	4.58e-05	7.33e-04	68
GO:0030323	GO:0030323	respiratory tube development	43/1669	122/8380	1.77	5.00e-05	7.95e-04	122
GO:0006953	GO:0006953	acute-phase response	18/1669	36/8380	2.51	5.04e-05	7.97e-04	36
GO:0034599	GO:0034599	cellular response to oxidative stress	48/1669	141/8380	1.71	5.19e-05	8.14e-04	141
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	44/1669	126/8380	1.75	5.29e-05	8.27e-04	126
GO:0043491	GO:0043491	protein kinase B signaling	51/1669	153/8380	1.67	5.76e-05	8.89e-04	153
GO:0002696	GO:0002696	positive regulation of leukocyte activation	66/1669	212/8380	1.56	5.85e-05	8.89e-04	212
GO:0071560	GO:0071560	cellular response to transforming growth factor beta stimulus	46/1669	134/8380	1.72	5.85e-05	8.89e-04	134
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	26/1669	62/8380	2.11	5.86e-05	8.89e-04	62
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	26/1669	62/8380	2.11	5.86e-05	8.89e-04	62
GO:0035296	GO:0035296	regulation of tube diameter	36/1669	97/8380	1.86	5.90e-05	8.89e-04	97
GO:0097746	GO:0097746	regulation of blood vessel diameter	36/1669	97/8380	1.86	5.90e-05	8.89e-04	97
GO:0010876	GO:0010876	lipid localization	76/1669	253/8380	1.51	6.39e-05	9.54e-04	253
GO:0006112	GO:0006112	energy reserve metabolic process	21/1669	46/8380	2.29	6.77e-05	9.99e-04	46
GO:0045123	GO:0045123	cellular extravasation	21/1669	46/8380	2.29	6.77e-05	9.99e-04	46
GO:1904035	GO:1904035	regulation of epithelial cell apoptotic process	21/1669	46/8380	2.29	6.77e-05	9.99e-04	46
GO:0072001	GO:0072001	renal system development	68/1669	221/8380	1.54	6.82e-05	1.00e-03	221
GO:0048017	GO:0048017	inositol lipid-mediated signaling	38/1669	105/8380	1.82	7.03e-05	1.02e-03	105
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	14/1669	25/8380	2.81	7.07e-05	1.02e-03	25
GO:1903672	GO:1903672	positive regulation of sprouting angiogenesis	14/1669	25/8380	2.81	7.07e-05	1.02e-03	25
GO:0002792	GO:0002792	negative regulation of peptide secretion	33/1669	87/8380	1.90	7.21e-05	1.03e-03	87
GO:0030324	GO:0030324	lung development	42/1669	120/8380	1.76	7.32e-05	1.04e-03	120
GO:0032642	GO:0032642	regulation of chemokine production	24/1669	56/8380	2.15	7.38e-05	1.04e-03	56
GO:0055017	GO:0055017	cardiac muscle tissue growth	24/1669	56/8380	2.15	7.38e-05	1.04e-03	56
GO:0071559	GO:0071559	response to transforming growth factor beta	47/1669	139/8380	1.70	7.48e-05	1.05e-03	139
GO:0060976	GO:0060976	coronary vasculature development	15/1669	28/8380	2.69	7.74e-05	1.08e-03	28
GO:1901653	GO:1901653	cellular response to peptide	59/1669	186/8380	1.59	7.94e-05	1.10e-03	186
GO:0060419	GO:0060419	heart growth	26/1669	63/8380	2.07	8.11e-05	1.12e-03	63
GO:0001655	GO:0001655	urogenital system development	74/1669	247/8380	1.50	8.74e-05	1.20e-03	247
GO:0060541	GO:0060541	respiratory system development	46/1669	136/8380	1.70	8.82e-05	1.21e-03	136
GO:0046889	GO:0046889	positive regulation of lipid biosynthetic process	22/1669	50/8380	2.21	9.08e-05	1.24e-03	50
GO:0032602	GO:0032602	chemokine production	25/1669	60/8380	2.09	9.19e-05	1.25e-03	60
GO:0003015	GO:0003015	heart process	58/1669	183/8380	1.59	9.33e-05	1.26e-03	183
GO:0003014	GO:0003014	renal system process	31/1669	81/8380	1.92	9.73e-05	1.31e-03	81
GO:0019915	GO:0019915	lipid storage	21/1669	47/8380	2.24	9.97e-05	1.33e-03	47
GO:0031348	GO:0031348	negative regulation of defense response	41/1669	118/8380	1.74	1.07e-04	1.42e-03	118
GO:1903671	GO:1903671	negative regulation of sprouting angiogenesis	10/1669	15/8380	3.35	1.07e-04	1.42e-03	15
GO:0071398	GO:0071398	cellular response to fatty acid	20/1669	44/8380	2.28	1.08e-04	1.43e-03	44
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	57/1669	180/8380	1.59	1.10e-04	1.44e-03	180
GO:0060401	GO:0060401	cytosolic calcium ion transport	38/1669	107/8380	1.78	1.12e-04	1.46e-03	107
GO:0042311	GO:0042311	vasodilation	13/1669	23/8380	2.84	1.13e-04	1.47e-03	23
GO:0045923	GO:0045923	positive regulation of fatty acid metabolic process	13/1669	23/8380	2.84	1.13e-04	1.47e-03	23
GO:0055021	GO:0055021	regulation of cardiac muscle tissue growth	19/1669	41/8380	2.33	1.17e-04	1.50e-03	41
GO:1901215	GO:1901215	negative regulation of neuron death	39/1669	111/8380	1.76	1.19e-04	1.53e-03	111
GO:0014074	GO:0014074	response to purine-containing compound	36/1669	100/8380	1.81	1.22e-04	1.56e-03	100
GO:0008016	GO:0008016	regulation of heart contraction	52/1669	161/8380	1.62	1.24e-04	1.56e-03	161
GO:0045428	GO:0045428	regulation of nitric oxide biosynthetic process	18/1669	38/8380	2.38	1.24e-04	1.56e-03	38
GO:0060047	GO:0060047	heart contraction	56/1669	177/8380	1.59	1.29e-04	1.62e-03	177
GO:0030593	GO:0030593	neutrophil chemotaxis	32/1669	86/8380	1.87	1.41e-04	1.75e-03	86
GO:0045926	GO:0045926	negative regulation of growth	52/1669	162/8380	1.61	1.48e-04	1.82e-03	162
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	44/1669	131/8380	1.69	1.49e-04	1.83e-03	131
GO:0006641	GO:0006641	triglyceride metabolic process	26/1669	65/8380	2.01	1.51e-04	1.84e-03	65
GO:0061448	GO:0061448	connective tissue development	59/1669	190/8380	1.56	1.53e-04	1.85e-03	190
GO:0051896	GO:0051896	regulation of protein kinase B signaling	45/1669	135/8380	1.67	1.54e-04	1.85e-03	135
GO:1904659	GO:1904659	glucose transmembrane transport	23/1669	55/8380	2.10	1.63e-04	1.94e-03	55
GO:0097530	GO:0097530	granulocyte migration	38/1669	109/8380	1.75	1.74e-04	2.07e-03	109
GO:0001822	GO:0001822	kidney development	63/1669	207/8380	1.53	1.76e-04	2.09e-03	207
GO:0090287	GO:0090287	regulation of cellular response to growth factor stimulus	53/1669	167/8380	1.59	1.77e-04	2.10e-03	167
GO:1903522	GO:1903522	regulation of blood circulation	60/1669	195/8380	1.54	1.79e-04	2.11e-03	195
GO:0010001	GO:0010001	glial cell differentiation	45/1669	136/8380	1.66	1.87e-04	2.18e-03	136
GO:0003044	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	18/1669	39/8380	2.32	1.88e-04	2.19e-03	39
GO:2000377	GO:2000377	regulation of reactive oxygen species metabolic process	36/1669	102/8380	1.77	1.93e-04	2.25e-03	102
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	24/1669	59/8380	2.04	1.97e-04	2.28e-03	59
GO:0010633	GO:0010633	negative regulation of epithelial cell migration	17/1669	36/8380	2.37	2.00e-04	2.31e-03	36
GO:0050886	GO:0050886	endocrine process	26/1669	66/8380	1.98	2.02e-04	2.32e-03	66
GO:0060402	GO:0060402	calcium ion transport into cytosol	37/1669	106/8380	1.75	2.05e-04	2.35e-03	106
GO:0061614	GO:0061614	pri-miRNA transcription by RNA polymerase II	14/1669	27/8380	2.60	2.13e-04	2.43e-03	27
GO:0055123	GO:0055123	digestive system development	38/1669	110/8380	1.73	2.16e-04	2.46e-03	110
GO:0016051	GO:0016051	carbohydrate biosynthetic process	39/1669	114/8380	1.72	2.26e-04	2.57e-03	114
GO:0071621	GO:0071621	granulocyte chemotaxis	35/1669	99/8380	1.78	2.27e-04	2.57e-03	99
GO:0090050	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	10/1669	16/8380	3.14	2.35e-04	2.65e-03	16
GO:1905952	GO:1905952	regulation of lipid localization	33/1669	92/8380	1.80	2.50e-04	2.81e-03	92
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	26/1669	67/8380	1.95	2.68e-04	3.00e-03	67
GO:0071216	GO:0071216	cellular response to biotic stimulus	45/1669	138/8380	1.64	2.71e-04	3.02e-03	138
GO:0051216	GO:0051216	cartilage development	49/1669	154/8380	1.60	2.86e-04	3.16e-03	154
GO:1900180	GO:1900180	regulation of protein localization to nucleus	21/1669	50/8380	2.11	2.89e-04	3.17e-03	50
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	57/1669	186/8380	1.54	2.89e-04	3.17e-03	186
GO:0120162	GO:0120162	positive regulation of cold-induced thermogenesis	25/1669	64/8380	1.96	3.11e-04	3.39e-03	64
GO:1990266	GO:1990266	neutrophil migration	33/1669	93/8380	1.78	3.14e-04	3.42e-03	93
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	30/1669	82/8380	1.84	3.18e-04	3.43e-03	82
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	30/1669	82/8380	1.84	3.18e-04	3.43e-03	82
GO:0061383	GO:0061383	trabecula morphogenesis	16/1669	34/8380	2.36	3.23e-04	3.47e-03	34
GO:0060395	GO:0060395	SMAD protein signal transduction	20/1669	47/8380	2.14	3.25e-04	3.48e-03	47
GO:0060420	GO:0060420	regulation of heart growth	20/1669	47/8380	2.14	3.25e-04	3.48e-03	47
GO:0050901	GO:0050901	leukocyte tethering or rolling	12/1669	22/8380	2.74	3.29e-04	3.50e-03	22
GO:0050870	GO:0050870	positive regulation of T cell activation	47/1669	147/8380	1.61	3.34e-04	3.54e-03	147
GO:0010883	GO:0010883	regulation of lipid storage	15/1669	31/8380	2.43	3.39e-04	3.56e-03	31
GO:0002526	GO:0002526	acute inflammatory response	39/1669	116/8380	1.69	3.40e-04	3.56e-03	116
GO:0050920	GO:0050920	regulation of chemotaxis	49/1669	155/8380	1.59	3.40e-04	3.56e-03	155
GO:0002793	GO:0002793	positive regulation of peptide secretion	55/1669	179/8380	1.54	3.41e-04	3.56e-03	179
GO:0098801	GO:0098801	regulation of renal system process	13/1669	25/8380	2.61	3.46e-04	3.60e-03	25
GO:1903409	GO:1903409	reactive oxygen species biosynthetic process	26/1669	68/8380	1.92	3.53e-04	3.66e-03	68
GO:0035265	GO:0035265	organ growth	41/1669	124/8380	1.66	3.60e-04	3.71e-03	124
GO:0010614	GO:0010614	negative regulation of cardiac muscle hypertrophy	9/1669	14/8380	3.23	3.65e-04	3.75e-03	14
GO:0030278	GO:0030278	regulation of ossification	42/1669	128/8380	1.65	3.69e-04	3.76e-03	128
GO:0048565	GO:0048565	digestive tract development	36/1669	105/8380	1.72	3.70e-04	3.76e-03	105
GO:0071772	GO:0071772	response to BMP	36/1669	105/8380	1.72	3.70e-04	3.76e-03	105
GO:0071773	GO:0071773	cellular response to BMP stimulus	36/1669	105/8380	1.72	3.70e-04	3.76e-03	105
GO:0035690	GO:0035690	cellular response to drug	60/1669	200/8380	1.51	3.80e-04	3.83e-03	200
GO:0008360	GO:0008360	regulation of cell shape	33/1669	94/8380	1.76	3.93e-04	3.94e-03	94
GO:0030856	GO:0030856	regulation of epithelial cell differentiation	33/1669	94/8380	1.76	3.93e-04	3.94e-03	94
GO:0042089	GO:0042089	cytokine biosynthetic process	27/1669	72/8380	1.88	3.95e-04	3.94e-03	72
GO:0015850	GO:0015850	organic hydroxy compound transport	55/1669	180/8380	1.53	3.98e-04	3.95e-03	180
GO:0051966	GO:0051966	regulation of synaptic transmission, glutamatergic	21/1669	51/8380	2.07	4.00e-04	3.97e-03	51
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	30/1669	83/8380	1.81	4.04e-04	4.00e-03	83
GO:1904019	GO:1904019	epithelial cell apoptotic process	23/1669	58/8380	1.99	4.14e-04	4.07e-03	58
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	34/1669	98/8380	1.74	4.16e-04	4.08e-03	98
GO:0045913	GO:0045913	positive regulation of carbohydrate metabolic process	20/1669	48/8380	2.09	4.54e-04	4.44e-03	48
GO:0060348	GO:0060348	bone development	45/1669	141/8380	1.60	4.63e-04	4.50e-03	141
GO:0001818	GO:0001818	negative regulation of cytokine production	52/1669	169/8380	1.54	4.71e-04	4.57e-03	169
GO:0050709	GO:0050709	negative regulation of protein secretion	29/1669	80/8380	1.82	4.74e-04	4.57e-03	80
GO:0010676	GO:0010676	positive regulation of cellular carbohydrate metabolic process	16/1669	35/8380	2.30	4.85e-04	4.67e-03	35
GO:0030509	GO:0030509	BMP signaling pathway	33/1669	95/8380	1.74	4.90e-04	4.70e-03	95
GO:0042107	GO:0042107	cytokine metabolic process	27/1669	73/8380	1.86	5.10e-04	4.85e-03	73
GO:0051952	GO:0051952	regulation of amine transport	27/1669	73/8380	1.86	5.10e-04	4.85e-03	73
GO:0051208	GO:0051208	sequestering of calcium ion	30/1669	84/8380	1.79	5.11e-04	4.85e-03	84
GO:0045601	GO:0045601	regulation of endothelial cell differentiation	11/1669	20/8380	2.76	5.33e-04	5.02e-03	20
GO:0051491	GO:0051491	positive regulation of filopodium assembly	11/1669	20/8380	2.76	5.33e-04	5.02e-03	20
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	25/1669	66/8380	1.90	5.38e-04	5.04e-03	66
GO:0006109	GO:0006109	regulation of carbohydrate metabolic process	31/1669	88/8380	1.77	5.45e-04	5.10e-03	88
GO:0048008	GO:0048008	platelet-derived growth factor receptor signaling pathway	14/1669	29/8380	2.42	5.50e-04	5.12e-03	29
GO:0008645	GO:0008645	hexose transmembrane transport	23/1669	59/8380	1.96	5.52e-04	5.12e-03	59
GO:1901655	GO:1901655	cellular response to ketone	23/1669	59/8380	1.96	5.52e-04	5.12e-03	59
GO:0006006	GO:0006006	glucose metabolic process	36/1669	107/8380	1.69	5.57e-04	5.14e-03	107
GO:0046321	GO:0046321	positive regulation of fatty acid oxidation	8/1669	12/8380	3.35	5.58e-04	5.14e-03	12
GO:0051580	GO:0051580	regulation of neurotransmitter uptake	8/1669	12/8380	3.35	5.58e-04	5.14e-03	12
GO:0019432	GO:0019432	triglyceride biosynthetic process	13/1669	26/8380	2.51	5.66e-04	5.20e-03	26
GO:0002687	GO:0002687	positive regulation of leukocyte migration	32/1669	92/8380	1.75	5.77e-04	5.28e-03	92
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	38/1669	115/8380	1.66	5.91e-04	5.39e-03	115
GO:0007179	GO:0007179	transforming growth factor beta receptor signaling pathway	33/1669	96/8380	1.73	6.06e-04	5.52e-03	96
GO:0003151	GO:0003151	outflow tract morphogenesis	24/1669	63/8380	1.91	6.27e-04	5.66e-03	63
GO:0060191	GO:0060191	regulation of lipase activity	24/1669	63/8380	1.91	6.27e-04	5.66e-03	63
GO:0062014	GO:0062014	negative regulation of small molecule metabolic process	22/1669	56/8380	1.97	6.39e-04	5.76e-03	56
GO:0090090	GO:0090090	negative regulation of canonical Wnt signaling pathway	30/1669	85/8380	1.77	6.42e-04	5.77e-03	85
GO:0003279	GO:0003279	cardiac septum development	27/1669	74/8380	1.83	6.53e-04	5.81e-03	74
GO:0010675	GO:0010675	regulation of cellular carbohydrate metabolic process	27/1669	74/8380	1.83	6.53e-04	5.81e-03	74
GO:0044706	GO:0044706	multi-multicellular organism process	47/1669	151/8380	1.56	6.53e-04	5.81e-03	151
GO:0050715	GO:0050715	positive regulation of cytokine secretion	31/1669	89/8380	1.75	6.80e-04	6.02e-03	89
GO:0001885	GO:0001885	endothelial cell development	16/1669	36/8380	2.23	7.14e-04	6.24e-03	36
GO:0043949	GO:0043949	regulation of cAMP-mediated signaling	16/1669	36/8380	2.23	7.14e-04	6.24e-03	36
GO:0046888	GO:0046888	negative regulation of hormone secretion	19/1669	46/8380	2.07	7.14e-04	6.24e-03	46
GO:1902930	GO:1902930	regulation of alcohol biosynthetic process	19/1669	46/8380	2.07	7.14e-04	6.24e-03	46
GO:0032868	GO:0032868	response to insulin	39/1669	120/8380	1.63	7.27e-04	6.34e-03	120
GO:0015749	GO:0015749	monosaccharide transmembrane transport	23/1669	60/8380	1.92	7.29e-04	6.34e-03	60
GO:0097306	GO:0097306	cellular response to alcohol	21/1669	53/8380	1.99	7.38e-04	6.40e-03	53
GO:0031649	GO:0031649	heat generation	9/1669	15/8380	3.01	7.51e-04	6.45e-03	15
GO:0035812	GO:0035812	renal sodium excretion	9/1669	15/8380	3.01	7.51e-04	6.45e-03	15
GO:0035813	GO:0035813	regulation of renal sodium excretion	9/1669	15/8380	3.01	7.51e-04	6.45e-03	15
GO:0042133	GO:0042133	neurotransmitter metabolic process	34/1669	101/8380	1.69	7.75e-04	6.63e-03	101
GO:2000351	GO:2000351	regulation of endothelial cell apoptotic process	15/1669	33/8380	2.28	7.82e-04	6.68e-03	33
GO:1903034	GO:1903034	regulation of response to wounding	35/1669	105/8380	1.67	8.00e-04	6.80e-03	105
GO:0045598	GO:0045598	regulation of fat cell differentiation	30/1669	86/8380	1.75	8.01e-04	6.80e-03	86
GO:0045600	GO:0045600	positive regulation of fat cell differentiation	18/1669	43/8380	2.10	8.11e-04	6.86e-03	43
GO:0007369	GO:0007369	gastrulation	36/1669	109/8380	1.66	8.22e-04	6.92e-03	109
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	36/1669	109/8380	1.66	8.22e-04	6.92e-03	109
GO:0031998	GO:0031998	regulation of fatty acid beta-oxidation	7/1669	10/8380	3.51	8.35e-04	6.94e-03	10
GO:0033605	GO:0033605	positive regulation of catecholamine secretion	7/1669	10/8380	3.51	8.35e-04	6.94e-03	10
GO:0042308	GO:0042308	negative regulation of protein import into nucleus	7/1669	10/8380	3.51	8.35e-04	6.94e-03	10
GO:0061050	GO:0061050	regulation of cell growth involved in cardiac muscle cell development	7/1669	10/8380	3.51	8.35e-04	6.94e-03	10
GO:1904590	GO:1904590	negative regulation of protein import	7/1669	10/8380	3.51	8.35e-04	6.94e-03	10
GO:0034754	GO:0034754	cellular hormone metabolic process	31/1669	90/8380	1.73	8.43e-04	6.98e-03	90
GO:1905954	GO:1905954	positive regulation of lipid localization	22/1669	57/8380	1.94	8.48e-04	7.00e-03	57
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	20/1669	50/8380	2.01	8.51e-04	7.01e-03	50
GO:0019882	GO:0019882	antigen processing and presentation	32/1669	94/8380	1.71	8.80e-04	7.24e-03	94
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	49/1669	161/8380	1.53	8.87e-04	7.28e-03	161
GO:0045429	GO:0045429	positive regulation of nitric oxide biosynthetic process	13/1669	27/8380	2.42	8.94e-04	7.30e-03	27
GO:1904407	GO:1904407	positive regulation of nitric oxide metabolic process	13/1669	27/8380	2.42	8.94e-04	7.30e-03	27
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	25/1669	68/8380	1.85	8.99e-04	7.31e-03	68
GO:0071453	GO:0071453	cellular response to oxygen levels	33/1669	98/8380	1.69	9.14e-04	7.41e-03	98
GO:0061437	GO:0061437	renal system vasculature development	11/1669	21/8380	2.63	9.20e-04	7.42e-03	21
GO:0061440	GO:0061440	kidney vasculature development	11/1669	21/8380	2.63	9.20e-04	7.42e-03	21
GO:0042572	GO:0042572	retinol metabolic process	12/1669	24/8380	2.51	9.24e-04	7.42e-03	24
GO:0034219	GO:0034219	carbohydrate transmembrane transport	23/1669	61/8380	1.89	9.54e-04	7.62e-03	61
GO:0030178	GO:0030178	negative regulation of Wnt signaling pathway	35/1669	106/8380	1.66	9.70e-04	7.73e-03	106
GO:0032231	GO:0032231	regulation of actin filament bundle assembly	21/1669	54/8380	1.95	9.85e-04	7.80e-03	54
GO:0060291	GO:0060291	long-term synaptic potentiation	21/1669	54/8380	1.95	9.85e-04	7.80e-03	54
GO:1903524	GO:1903524	positive regulation of blood circulation	21/1669	54/8380	1.95	9.85e-04	7.80e-03	54
GO:0046545	GO:0046545	development of primary female sexual characteristics	24/1669	65/8380	1.85	1.05e-03	8.27e-03	65
GO:0050818	GO:0050818	regulation of coagulation	24/1669	65/8380	1.85	1.05e-03	8.27e-03	65
GO:0048738	GO:0048738	cardiac muscle tissue development	43/1669	138/8380	1.56	1.06e-03	8.29e-03	138
GO:0006638	GO:0006638	neutral lipid metabolic process	28/1669	80/8380	1.76	1.11e-03	8.65e-03	80
GO:0015837	GO:0015837	amine transport	28/1669	80/8380	1.76	1.11e-03	8.65e-03	80
GO:0003281	GO:0003281	ventricular septum development	20/1669	51/8380	1.97	1.14e-03	8.81e-03	51
GO:0033138	GO:0033138	positive regulation of peptidyl-serine phosphorylation	20/1669	51/8380	1.97	1.14e-03	8.81e-03	51
GO:0010878	GO:0010878	cholesterol storage	8/1669	13/8380	3.09	1.20e-03	9.15e-03	13
GO:0051767	GO:0051767	nitric-oxide synthase biosynthetic process	8/1669	13/8380	3.09	1.20e-03	9.15e-03	13
GO:0051769	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	8/1669	13/8380	3.09	1.20e-03	9.15e-03	13
GO:0007565	GO:0007565	female pregnancy	40/1669	127/8380	1.58	1.24e-03	9.45e-03	127
GO:0010810	GO:0010810	regulation of cell-substrate adhesion	42/1669	135/8380	1.56	1.25e-03	9.47e-03	135
GO:0050873	GO:0050873	brown fat cell differentiation	14/1669	31/8380	2.27	1.26e-03	9.54e-03	31
GO:0008277	GO:0008277	regulation of G protein-coupled receptor signaling pathway	31/1669	92/8380	1.69	1.27e-03	9.60e-03	92
GO:0030858	GO:0030858	positive regulation of epithelial cell differentiation	17/1669	41/8380	2.08	1.28e-03	9.61e-03	41
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	21/1669	55/8380	1.92	1.30e-03	9.74e-03	55
GO:0002027	GO:0002027	regulation of heart rate	27/1669	77/8380	1.76	1.31e-03	9.83e-03	77
GO:0043255	GO:0043255	regulation of carbohydrate biosynthetic process	19/1669	48/8380	1.99	1.32e-03	9.87e-03	48
GO:0008207	GO:0008207	C21-steroid hormone metabolic process	13/1669	28/8380	2.33	1.37e-03	1.01e-02	28
GO:0046460	GO:0046460	neutral lipid biosynthetic process	13/1669	28/8380	2.33	1.37e-03	1.01e-02	28
GO:0046461	GO:0046461	neutral lipid catabolic process	13/1669	28/8380	2.33	1.37e-03	1.01e-02	28
GO:0046463	GO:0046463	acylglycerol biosynthetic process	13/1669	28/8380	2.33	1.37e-03	1.01e-02	28
GO:0046464	GO:0046464	acylglycerol catabolic process	13/1669	28/8380	2.33	1.37e-03	1.01e-02	28
GO:0050714	GO:0050714	positive regulation of protein secretion	49/1669	164/8380	1.50	1.38e-03	1.01e-02	164
GO:0002021	GO:0002021	response to dietary excess	9/1669	16/8380	2.82	1.41e-03	1.03e-02	16
GO:0002043	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	9/1669	16/8380	2.82	1.41e-03	1.03e-02	16
GO:0014741	GO:0014741	negative regulation of muscle hypertrophy	9/1669	16/8380	2.82	1.41e-03	1.03e-02	16
GO:0060669	GO:0060669	embryonic placenta morphogenesis	9/1669	16/8380	2.82	1.41e-03	1.03e-02	16
GO:1904894	GO:1904894	positive regulation of STAT cascade	22/1669	59/8380	1.87	1.45e-03	1.05e-02	59
GO:0032355	GO:0032355	response to estradiol	29/1669	85/8380	1.71	1.45e-03	1.05e-02	85
GO:0010827	GO:0010827	regulation of glucose transmembrane transport	16/1669	38/8380	2.11	1.45e-03	1.05e-02	38
GO:0048662	GO:0048662	negative regulation of smooth muscle cell proliferation	16/1669	38/8380	2.11	1.45e-03	1.05e-02	38
GO:0019433	GO:0019433	triglyceride catabolic process	12/1669	25/8380	2.41	1.46e-03	1.05e-02	25
GO:0050866	GO:0050866	negative regulation of cell activation	40/1669	128/8380	1.57	1.47e-03	1.05e-02	128
GO:0007584	GO:0007584	response to nutrient	41/1669	132/8380	1.56	1.47e-03	1.05e-02	132
GO:0071276	GO:0071276	cellular response to cadmium ion	10/1669	19/8380	2.64	1.51e-03	1.06e-02	19
GO:0072012	GO:0072012	glomerulus vasculature development	10/1669	19/8380	2.64	1.51e-03	1.06e-02	19
GO:0085029	GO:0085029	extracellular matrix assembly	10/1669	19/8380	2.64	1.51e-03	1.06e-02	19
GO:0097009	GO:0097009	energy homeostasis	10/1669	19/8380	2.64	1.51e-03	1.06e-02	19
GO:0034405	GO:0034405	response to fluid shear stress	11/1669	22/8380	2.51	1.51e-03	1.06e-02	22
GO:0051968	GO:0051968	positive regulation of synaptic transmission, glutamatergic	11/1669	22/8380	2.51	1.51e-03	1.06e-02	22
GO:0014897	GO:0014897	striated muscle hypertrophy	20/1669	52/8380	1.93	1.51e-03	1.06e-02	52
GO:0048247	GO:0048247	lymphocyte chemotaxis	20/1669	52/8380	1.93	1.51e-03	1.06e-02	52
GO:1901888	GO:1901888	regulation of cell junction assembly	18/1669	45/8380	2.01	1.52e-03	1.07e-02	45
GO:0003231	GO:0003231	cardiac ventricle development	31/1669	93/8380	1.67	1.55e-03	1.08e-02	93
GO:0061041	GO:0061041	regulation of wound healing	31/1669	93/8380	1.67	1.55e-03	1.08e-02	93
GO:0030193	GO:0030193	regulation of blood coagulation	23/1669	63/8380	1.83	1.58e-03	1.10e-02	63
GO:1900046	GO:1900046	regulation of hemostasis	23/1669	63/8380	1.83	1.58e-03	1.10e-02	63
GO:0032768	GO:0032768	regulation of monooxygenase activity	15/1669	35/8380	2.15	1.64e-03	1.12e-02	35
GO:0050994	GO:0050994	regulation of lipid catabolic process	15/1669	35/8380	2.15	1.64e-03	1.12e-02	35
GO:0072577	GO:0072577	endothelial cell apoptotic process	15/1669	35/8380	2.15	1.64e-03	1.12e-02	35
GO:0044262	GO:0044262	cellular carbohydrate metabolic process	43/1669	141/8380	1.53	1.70e-03	1.17e-02	141
GO:0045833	GO:0045833	negative regulation of lipid metabolic process	19/1669	49/8380	1.95	1.76e-03	1.20e-02	49
GO:0032635	GO:0032635	interleukin-6 production	29/1669	86/8380	1.69	1.78e-03	1.20e-02	86
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	14/1669	32/8380	2.20	1.83e-03	1.23e-02	32
GO:0043618	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	14/1669	32/8380	2.20	1.83e-03	1.23e-02	32
GO:0071675	GO:0071675	regulation of mononuclear cell migration	14/1669	32/8380	2.20	1.83e-03	1.23e-02	32
GO:0036294	GO:0036294	cellular response to decreased oxygen levels	30/1669	90/8380	1.67	1.84e-03	1.23e-02	90
GO:0043524	GO:0043524	negative regulation of neuron apoptotic process	30/1669	90/8380	1.67	1.84e-03	1.23e-02	90
GO:0010885	GO:0010885	regulation of cholesterol storage	7/1669	11/8380	3.20	1.90e-03	1.26e-02	11
GO:0046823	GO:0046823	negative regulation of nucleocytoplasmic transport	7/1669	11/8380	3.20	1.90e-03	1.26e-02	11
GO:0051770	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	7/1669	11/8380	3.20	1.90e-03	1.26e-02	11
GO:0060347	GO:0060347	heart trabecula formation	7/1669	11/8380	3.20	1.90e-03	1.26e-02	11
GO:1903587	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	7/1669	11/8380	3.20	1.90e-03	1.26e-02	11
GO:0008643	GO:0008643	carbohydrate transport	26/1669	75/8380	1.74	1.93e-03	1.27e-02	75
GO:0034440	GO:0034440	lipid oxidation	20/1669	53/8380	1.89	1.98e-03	1.31e-02	53
GO:0006639	GO:0006639	acylglycerol metabolic process	27/1669	79/8380	1.72	2.02e-03	1.33e-02	79
GO:0048566	GO:0048566	embryonic digestive tract development	13/1669	29/8380	2.25	2.03e-03	1.33e-02	29
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	28/1669	83/8380	1.69	2.10e-03	1.38e-02	83
GO:0071456	GO:0071456	cellular response to hypoxia	29/1669	87/8380	1.67	2.17e-03	1.41e-02	87
GO:0010906	GO:0010906	regulation of glucose metabolic process	21/1669	57/8380	1.85	2.19e-03	1.41e-02	57
GO:0033555	GO:0033555	multicellular organismal response to stress	21/1669	57/8380	1.85	2.19e-03	1.41e-02	57
GO:0045778	GO:0045778	positive regulation of ossification	21/1669	57/8380	1.85	2.19e-03	1.41e-02	57
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	21/1669	57/8380	1.85	2.19e-03	1.41e-02	57
GO:0055024	GO:0055024	regulation of cardiac muscle tissue development	21/1669	57/8380	1.85	2.19e-03	1.41e-02	57
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	12/1669	26/8380	2.32	2.22e-03	1.43e-02	26
GO:0043112	GO:0043112	receptor metabolic process	30/1669	91/8380	1.66	2.23e-03	1.43e-02	91
GO:0090288	GO:0090288	negative regulation of cellular response to growth factor stimulus	30/1669	91/8380	1.66	2.23e-03	1.43e-02	91
GO:0043266	GO:0043266	regulation of potassium ion transport	25/1669	72/8380	1.74	2.28e-03	1.46e-02	72
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	15/1669	36/8380	2.09	2.30e-03	1.47e-02	36
GO:1904705	GO:1904705	regulation of vascular smooth muscle cell proliferation	15/1669	36/8380	2.09	2.30e-03	1.47e-02	36
GO:1990874	GO:1990874	vascular smooth muscle cell proliferation	15/1669	36/8380	2.09	2.30e-03	1.47e-02	36
GO:0003094	GO:0003094	glomerular filtration	8/1669	14/8380	2.87	2.31e-03	1.47e-02	14
GO:0061418	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	8/1669	14/8380	2.87	2.31e-03	1.47e-02	14
GO:0003300	GO:0003300	cardiac muscle hypertrophy	19/1669	50/8380	1.91	2.32e-03	1.47e-02	50
GO:0031623	GO:0031623	receptor internalization	22/1669	61/8380	1.81	2.37e-03	1.49e-02	61
GO:0046620	GO:0046620	regulation of organ growth	22/1669	61/8380	1.81	2.37e-03	1.49e-02	61
GO:0019318	GO:0019318	hexose metabolic process	39/1669	127/8380	1.54	2.38e-03	1.49e-02	127
GO:0006692	GO:0006692	prostanoid metabolic process	11/1669	23/8380	2.40	2.38e-03	1.49e-02	23
GO:0006693	GO:0006693	prostaglandin metabolic process	11/1669	23/8380	2.40	2.38e-03	1.49e-02	23
GO:0043267	GO:0043267	negative regulation of potassium ion transport	11/1669	23/8380	2.40	2.38e-03	1.49e-02	23
GO:0050806	GO:0050806	positive regulation of synaptic transmission	36/1669	115/8380	1.57	2.39e-03	1.49e-02	115
GO:0034695	GO:0034695	response to prostaglandin E	9/1669	17/8380	2.66	2.48e-03	1.53e-02	17
GO:0043950	GO:0043950	positive regulation of cAMP-mediated signaling	9/1669	17/8380	2.66	2.48e-03	1.53e-02	17
GO:0044062	GO:0044062	regulation of excretion	9/1669	17/8380	2.66	2.48e-03	1.53e-02	17
GO:1904037	GO:1904037	positive regulation of epithelial cell apoptotic process	9/1669	17/8380	2.66	2.48e-03	1.53e-02	17
GO:0019233	GO:0019233	sensory perception of pain	27/1669	80/8380	1.69	2.48e-03	1.53e-02	80
GO:0032675	GO:0032675	regulation of interleukin-6 production	27/1669	80/8380	1.69	2.48e-03	1.53e-02	80
GO:0060021	GO:0060021	roof of mouth development	23/1669	65/8380	1.78	2.54e-03	1.57e-02	65
GO:0014896	GO:0014896	muscle hypertrophy	20/1669	54/8380	1.86	2.57e-03	1.58e-02	54
GO:0022602	GO:0022602	ovulation cycle process	14/1669	33/8380	2.13	2.61e-03	1.59e-02	33
GO:0032387	GO:0032387	negative regulation of intracellular transport	14/1669	33/8380	2.13	2.61e-03	1.59e-02	33
GO:0046887	GO:0046887	positive regulation of hormone secretion	30/1669	92/8380	1.64	2.69e-03	1.64e-02	92
GO:0042136	GO:0042136	neurotransmitter biosynthetic process	24/1669	69/8380	1.75	2.69e-03	1.64e-02	69
GO:0110053	GO:0110053	regulation of actin filament organization	42/1669	140/8380	1.51	2.70e-03	1.64e-02	140
GO:0001508	GO:0001508	action potential	31/1669	96/8380	1.62	2.73e-03	1.65e-02	96
GO:0050921	GO:0050921	positive regulation of chemotaxis	31/1669	96/8380	1.62	2.73e-03	1.65e-02	96
GO:0061572	GO:0061572	actin filament bundle organization	31/1669	96/8380	1.62	2.73e-03	1.65e-02	96
GO:0031294	GO:0031294	lymphocyte costimulation	16/1669	40/8380	2.01	2.74e-03	1.65e-02	40
GO:0060389	GO:0060389	pathway-restricted SMAD protein phosphorylation	16/1669	40/8380	2.01	2.74e-03	1.65e-02	40
GO:0048661	GO:0048661	positive regulation of smooth muscle cell proliferation	21/1669	58/8380	1.82	2.80e-03	1.68e-02	58
GO:0060411	GO:0060411	cardiac septum morphogenesis	21/1669	58/8380	1.82	2.80e-03	1.68e-02	58
GO:0010611	GO:0010611	regulation of cardiac muscle hypertrophy	13/1669	30/8380	2.18	2.94e-03	1.75e-02	30
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	22/1669	62/8380	1.78	3.00e-03	1.78e-02	62
GO:0008585	GO:0008585	female gonad development	22/1669	62/8380	1.78	3.00e-03	1.78e-02	62
GO:0072676	GO:0072676	lymphocyte migration	28/1669	85/8380	1.65	3.11e-03	1.84e-02	85
GO:0050710	GO:0050710	negative regulation of cytokine secretion	17/1669	44/8380	1.94	3.16e-03	1.86e-02	44
GO:0050819	GO:0050819	negative regulation of coagulation	17/1669	44/8380	1.94	3.16e-03	1.86e-02	44
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	41/1669	137/8380	1.50	3.16e-03	1.86e-02	137
GO:0010463	GO:0010463	mesenchymal cell proliferation	15/1669	37/8380	2.04	3.17e-03	1.86e-02	37
GO:0010524	GO:0010524	positive regulation of calcium ion transport into cytosol	15/1669	37/8380	2.04	3.17e-03	1.86e-02	37
GO:0015908	GO:0015908	fatty acid transport	23/1669	66/8380	1.75	3.18e-03	1.86e-02	66
GO:0001649	GO:0001649	osteoblast differentiation	40/1669	133/8380	1.51	3.20e-03	1.87e-02	133
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	30/1669	93/8380	1.62	3.23e-03	1.88e-02	93
GO:0010543	GO:0010543	regulation of platelet activation	12/1669	27/8380	2.23	3.28e-03	1.91e-02	27
GO:0051489	GO:0051489	regulation of filopodium assembly	12/1669	27/8380	2.23	3.28e-03	1.91e-02	27
GO:0043271	GO:0043271	negative regulation of ion transport	32/1669	101/8380	1.59	3.29e-03	1.91e-02	101
GO:0048640	GO:0048640	negative regulation of developmental growth	25/1669	74/8380	1.70	3.47e-03	2.01e-02	74
GO:0090100	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	21/1669	59/8380	1.79	3.54e-03	2.04e-02	59
GO:0006721	GO:0006721	terpenoid metabolic process	26/1669	78/8380	1.67	3.59e-03	2.06e-02	78
GO:0007190	GO:0007190	activation of adenylate cyclase activity	11/1669	24/8380	2.30	3.61e-03	2.06e-02	24
GO:0010742	GO:0010742	macrophage derived foam cell differentiation	11/1669	24/8380	2.30	3.61e-03	2.06e-02	24
GO:0043552	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	11/1669	24/8380	2.30	3.61e-03	2.06e-02	24
GO:0090077	GO:0090077	foam cell differentiation	11/1669	24/8380	2.30	3.61e-03	2.06e-02	24
GO:0099084	GO:0099084	postsynaptic specialization organization	11/1669	24/8380	2.30	3.61e-03	2.06e-02	24
GO:0032615	GO:0032615	interleukin-12 production	14/1669	34/8380	2.07	3.64e-03	2.06e-02	34
GO:0045744	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	14/1669	34/8380	2.07	3.64e-03	2.06e-02	34
GO:0086009	GO:0086009	membrane repolarization	14/1669	34/8380	2.07	3.64e-03	2.06e-02	34
GO:0001890	GO:0001890	placenta development	28/1669	86/8380	1.63	3.76e-03	2.10e-02	86
GO:0003198	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0010888	GO:0010888	negative regulation of lipid storage	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0030730	GO:0030730	sequestering of triglyceride	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0032682	GO:0032682	negative regulation of chemokine production	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0035994	GO:0035994	response to muscle stretch	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0042448	GO:0042448	progesterone metabolic process	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:1902644	GO:1902644	tertiary alcohol metabolic process	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:1904994	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	7/1669	12/8380	2.93	3.78e-03	2.10e-02	12
GO:0034504	GO:0034504	protein localization to nucleus	30/1669	94/8380	1.60	3.86e-03	2.14e-02	94
GO:0051017	GO:0051017	actin filament bundle assembly	30/1669	94/8380	1.60	3.86e-03	2.14e-02	94
GO:0051341	GO:0051341	regulation of oxidoreductase activity	19/1669	52/8380	1.83	3.88e-03	2.14e-02	52
GO:0002026	GO:0002026	regulation of the force of heart contraction	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:0010743	GO:0010743	regulation of macrophage derived foam cell differentiation	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:0010907	GO:0010907	positive regulation of glucose metabolic process	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:0035767	GO:0035767	endothelial cell chemotaxis	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:0090317	GO:0090317	negative regulation of intracellular protein transport	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:1902932	GO:1902932	positive regulation of alcohol biosynthetic process	10/1669	21/8380	2.39	3.90e-03	2.14e-02	21
GO:0001516	GO:0001516	prostaglandin biosynthetic process	9/1669	18/8380	2.51	4.09e-03	2.21e-02	18
GO:0035886	GO:0035886	vascular smooth muscle cell differentiation	9/1669	18/8380	2.51	4.09e-03	2.21e-02	18
GO:0046457	GO:0046457	prostanoid biosynthetic process	9/1669	18/8380	2.51	4.09e-03	2.21e-02	18
GO:0071379	GO:0071379	cellular response to prostaglandin stimulus	9/1669	18/8380	2.51	4.09e-03	2.21e-02	18
GO:0098698	GO:0098698	postsynaptic specialization assembly	9/1669	18/8380	2.51	4.09e-03	2.21e-02	18
GO:0042474	GO:0042474	middle ear morphogenesis	8/1669	15/8380	2.68	4.09e-03	2.21e-02	15
GO:0050995	GO:0050995	negative regulation of lipid catabolic process	8/1669	15/8380	2.68	4.09e-03	2.21e-02	15
GO:0097205	GO:0097205	renal filtration	8/1669	15/8380	2.68	4.09e-03	2.21e-02	15
GO:0071236	GO:0071236	cellular response to antibiotic	24/1669	71/8380	1.70	4.11e-03	2.21e-02	71
GO:0090101	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	24/1669	71/8380	1.70	4.11e-03	2.21e-02	71
GO:0001990	GO:0001990	regulation of systemic arterial blood pressure by hormone	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:0042306	GO:0042306	regulation of protein import into nucleus	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:0045823	GO:0045823	positive regulation of heart contraction	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:0090278	GO:0090278	negative regulation of peptide hormone secretion	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:1903428	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:1904589	GO:1904589	regulation of protein import	13/1669	31/8380	2.11	4.16e-03	2.22e-02	31
GO:0014812	GO:0014812	muscle cell migration	20/1669	56/8380	1.79	4.19e-03	2.23e-02	56
GO:0001706	GO:0001706	endoderm formation	15/1669	38/8380	1.98	4.28e-03	2.27e-02	38
GO:0046660	GO:0046660	female sex differentiation	26/1669	79/8380	1.65	4.35e-03	2.30e-02	79
GO:2001023	GO:2001023	regulation of response to drug	21/1669	60/8380	1.76	4.45e-03	2.35e-02	60
GO:0061035	GO:0061035	regulation of cartilage development	18/1669	49/8380	1.84	4.58e-03	2.40e-02	49
GO:0110020	GO:0110020	regulation of actomyosin structure organization	18/1669	49/8380	1.84	4.58e-03	2.40e-02	49
GO:0046323	GO:0046323	glucose import	12/1669	28/8380	2.15	4.72e-03	2.47e-02	28
GO:0051281	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	12/1669	28/8380	2.15	4.72e-03	2.47e-02	28
GO:0001523	GO:0001523	retinoid metabolic process	23/1669	68/8380	1.70	4.87e-03	2.52e-02	68
GO:0021782	GO:0021782	glial cell development	23/1669	68/8380	1.70	4.87e-03	2.52e-02	68
GO:0030195	GO:0030195	negative regulation of blood coagulation	16/1669	42/8380	1.91	4.87e-03	2.52e-02	42
GO:0032722	GO:0032722	positive regulation of chemokine production	16/1669	42/8380	1.91	4.87e-03	2.52e-02	42
GO:0070301	GO:0070301	cellular response to hydrogen peroxide	16/1669	42/8380	1.91	4.87e-03	2.52e-02	42
GO:1900047	GO:1900047	negative regulation of hemostasis	16/1669	42/8380	1.91	4.87e-03	2.52e-02	42
GO:0001892	GO:0001892	embryonic placenta development	19/1669	53/8380	1.80	4.95e-03	2.55e-02	53
GO:0043620	GO:0043620	regulation of DNA-templated transcription in response to stress	14/1669	35/8380	2.01	4.97e-03	2.56e-02	35
GO:0016101	GO:0016101	diterpenoid metabolic process	24/1669	72/8380	1.67	5.03e-03	2.58e-02	72
GO:0030282	GO:0030282	bone mineralization	25/1669	76/8380	1.65	5.16e-03	2.64e-02	76
GO:0001704	GO:0001704	formation of primary germ layer	26/1669	80/8380	1.63	5.26e-03	2.69e-02	80
GO:0002534	GO:0002534	cytokine production involved in inflammatory response	11/1669	25/8380	2.21	5.31e-03	2.70e-02	25
GO:0042304	GO:0042304	regulation of fatty acid biosynthetic process	11/1669	25/8380	2.21	5.31e-03	2.70e-02	25
GO:0055023	GO:0055023	positive regulation of cardiac muscle tissue growth	11/1669	25/8380	2.21	5.31e-03	2.70e-02	25
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	21/1669	61/8380	1.73	5.54e-03	2.81e-02	61
GO:0031295	GO:0031295	T cell costimulation	15/1669	39/8380	1.93	5.70e-03	2.87e-02	39
GO:0032677	GO:0032677	regulation of interleukin-8 production	15/1669	39/8380	1.93	5.70e-03	2.87e-02	39
GO:0048546	GO:0048546	digestive tract morphogenesis	15/1669	39/8380	1.93	5.70e-03	2.87e-02	39
GO:0072132	GO:0072132	mesenchyme morphogenesis	15/1669	39/8380	1.93	5.70e-03	2.87e-02	39
GO:0010863	GO:0010863	positive regulation of phospholipase C activity	13/1669	32/8380	2.04	5.74e-03	2.87e-02	32
GO:0014743	GO:0014743	regulation of muscle hypertrophy	13/1669	32/8380	2.04	5.74e-03	2.87e-02	32
GO:0051893	GO:0051893	regulation of focal adhesion assembly	13/1669	32/8380	2.04	5.74e-03	2.87e-02	32
GO:0090109	GO:0090109	regulation of cell-substrate junction assembly	13/1669	32/8380	2.04	5.74e-03	2.87e-02	32
GO:0010517	GO:0010517	regulation of phospholipase activity	18/1669	50/8380	1.81	5.84e-03	2.92e-02	50
GO:0050810	GO:0050810	regulation of steroid biosynthetic process	18/1669	50/8380	1.81	5.84e-03	2.92e-02	50
GO:0007202	GO:0007202	activation of phospholipase C activity	10/1669	22/8380	2.28	5.89e-03	2.92e-02	22
GO:0043114	GO:0043114	regulation of vascular permeability	10/1669	22/8380	2.28	5.89e-03	2.92e-02	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	10/1669	22/8380	2.28	5.89e-03	2.92e-02	22
GO:0097106	GO:0097106	postsynaptic density organization	10/1669	22/8380	2.28	5.89e-03	2.92e-02	22
GO:1902893	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	10/1669	22/8380	2.28	5.89e-03	2.92e-02	22
GO:0033135	GO:0033135	regulation of peptidyl-serine phosphorylation	23/1669	69/8380	1.67	5.96e-03	2.94e-02	69
GO:0035249	GO:0035249	synaptic transmission, glutamatergic	23/1669	69/8380	1.67	5.96e-03	2.94e-02	69
GO:0001886	GO:0001886	endothelial cell morphogenesis	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0002430	GO:0002430	complement receptor mediated signaling pathway	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0010566	GO:0010566	regulation of ketone biosynthetic process	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0016102	GO:0016102	diterpenoid biosynthetic process	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0032490	GO:0032490	detection of molecule of bacterial origin	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0042362	GO:0042362	fat-soluble vitamin biosynthetic process	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0043116	GO:0043116	negative regulation of vascular permeability	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0044126	GO:0044126	regulation of growth of symbiont in host	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0044130	GO:0044130	negative regulation of growth of symbiont in host	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:1903392	GO:1903392	negative regulation of adherens junction organization	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:2000833	GO:2000833	positive regulation of steroid hormone secretion	6/1669	10/8380	3.01	6.20e-03	3.01e-02	10
GO:0050680	GO:0050680	negative regulation of epithelial cell proliferation	25/1669	77/8380	1.63	6.22e-03	3.01e-02	77
GO:0050918	GO:0050918	positive chemotaxis	19/1669	54/8380	1.77	6.24e-03	3.01e-02	54
GO:0006939	GO:0006939	smooth muscle contraction	26/1669	81/8380	1.61	6.31e-03	3.04e-02	81
GO:0019886	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	16/1669	43/8380	1.87	6.35e-03	3.04e-02	43
GO:0032637	GO:0032637	interleukin-8 production	16/1669	43/8380	1.87	6.35e-03	3.04e-02	43
GO:0071384	GO:0071384	cellular response to corticosteroid stimulus	16/1669	43/8380	1.87	6.35e-03	3.04e-02	43
GO:0050777	GO:0050777	negative regulation of immune response	28/1669	89/8380	1.58	6.40e-03	3.05e-02	89
GO:0007612	GO:0007612	learning	30/1669	97/8380	1.55	6.40e-03	3.05e-02	97
GO:0046885	GO:0046885	regulation of hormone biosynthetic process	9/1669	19/8380	2.38	6.41e-03	3.05e-02	19
GO:0061082	GO:0061082	myeloid leukocyte cytokine production	9/1669	19/8380	2.38	6.41e-03	3.05e-02	19
GO:0090025	GO:0090025	regulation of monocyte chemotaxis	9/1669	19/8380	2.38	6.41e-03	3.05e-02	19
GO:0003208	GO:0003208	cardiac ventricle morphogenesis	20/1669	58/8380	1.73	6.57e-03	3.12e-02	58
GO:0098869	GO:0098869	cellular oxidant detoxification	20/1669	58/8380	1.73	6.57e-03	3.12e-02	58
GO:0014009	GO:0014009	glial cell proliferation	12/1669	29/8380	2.08	6.61e-03	3.12e-02	29
GO:0032570	GO:0032570	response to progesterone	12/1669	29/8380	2.08	6.61e-03	3.12e-02	29
GO:0060421	GO:0060421	positive regulation of heart growth	12/1669	29/8380	2.08	6.61e-03	3.12e-02	29
GO:0120163	GO:0120163	negative regulation of cold-induced thermogenesis	12/1669	29/8380	2.08	6.61e-03	3.12e-02	29
GO:0002686	GO:0002686	negative regulation of leukocyte migration	14/1669	36/8380	1.95	6.67e-03	3.12e-02	36
GO:0006700	GO:0006700	C21-steroid hormone biosynthetic process	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:0010544	GO:0010544	negative regulation of platelet activation	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:0055022	GO:0055022	negative regulation of cardiac muscle tissue growth	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:0061117	GO:0061117	negative regulation of heart growth	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:0071677	GO:0071677	positive regulation of mononuclear cell migration	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:1900181	GO:1900181	negative regulation of protein localization to nucleus	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:1904706	GO:1904706	negative regulation of vascular smooth muscle cell proliferation	8/1669	16/8380	2.51	6.77e-03	3.12e-02	16
GO:0007194	GO:0007194	negative regulation of adenylate cyclase activity	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0019430	GO:0019430	removal of superoxide radicals	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0045922	GO:0045922	negative regulation of fatty acid metabolic process	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0048305	GO:0048305	immunoglobulin secretion	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0060330	GO:0060330	regulation of response to interferon-gamma	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0060334	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0060390	GO:0060390	regulation of SMAD protein signal transduction	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0071450	GO:0071450	cellular response to oxygen radical	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0071451	GO:0071451	cellular response to superoxide	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0071498	GO:0071498	cellular response to fluid shear stress	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:1901889	GO:1901889	negative regulation of cell junction assembly	7/1669	13/8380	2.70	6.79e-03	3.12e-02	13
GO:0033273	GO:0033273	response to vitamin	21/1669	62/8380	1.70	6.84e-03	3.13e-02	62
GO:0006968	GO:0006968	cellular defense response	17/1669	47/8380	1.82	6.91e-03	3.14e-02	47
GO:0014909	GO:0014909	smooth muscle cell migration	17/1669	47/8380	1.82	6.91e-03	3.14e-02	47
GO:0015909	GO:0015909	long-chain fatty acid transport	17/1669	47/8380	1.82	6.91e-03	3.14e-02	47
GO:0048145	GO:0048145	regulation of fibroblast proliferation	17/1669	47/8380	1.82	6.91e-03	3.14e-02	47
GO:0003073	GO:0003073	regulation of systemic arterial blood pressure	23/1669	70/8380	1.65	7.24e-03	3.28e-02	70
GO:0002673	GO:0002673	regulation of acute inflammatory response	24/1669	74/8380	1.63	7.37e-03	3.31e-02	74
GO:0098754	GO:0098754	detoxification	24/1669	74/8380	1.63	7.37e-03	3.31e-02	74
GO:0031214	GO:0031214	biomineral tissue development	32/1669	106/8380	1.52	7.38e-03	3.31e-02	106
GO:0001841	GO:0001841	neural tube formation	18/1669	51/8380	1.77	7.39e-03	3.31e-02	51
GO:0019395	GO:0019395	fatty acid oxidation	18/1669	51/8380	1.77	7.39e-03	3.31e-02	51
GO:0030038	GO:0030038	contractile actin filament bundle assembly	18/1669	51/8380	1.77	7.39e-03	3.31e-02	51
GO:0043149	GO:0043149	stress fiber assembly	18/1669	51/8380	1.77	7.39e-03	3.31e-02	51
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	25/1669	78/8380	1.61	7.47e-03	3.33e-02	78
GO:0043550	GO:0043550	regulation of lipid kinase activity	15/1669	40/8380	1.88	7.47e-03	3.33e-02	40
GO:0046503	GO:0046503	glycerolipid catabolic process	15/1669	40/8380	1.88	7.47e-03	3.33e-02	40
GO:0010811	GO:0010811	positive regulation of cell-substrate adhesion	26/1669	82/8380	1.59	7.53e-03	3.35e-02	82
GO:0033762	GO:0033762	response to glucagon	11/1669	26/8380	2.12	7.57e-03	3.35e-02	26
GO:0060317	GO:0060317	cardiac epithelial to mesenchymal transition	11/1669	26/8380	2.12	7.57e-03	3.35e-02	26
GO:0090218	GO:0090218	positive regulation of lipid kinase activity	11/1669	26/8380	2.12	7.57e-03	3.35e-02	26
GO:0099174	GO:0099174	regulation of presynapse organization	11/1669	26/8380	2.12	7.57e-03	3.35e-02	26
GO:1903053	GO:1903053	regulation of extracellular matrix organization	11/1669	26/8380	2.12	7.57e-03	3.35e-02	26
GO:0032655	GO:0032655	regulation of interleukin-12 production	13/1669	33/8380	1.98	7.78e-03	3.41e-02	33
GO:0046850	GO:0046850	regulation of bone remodeling	13/1669	33/8380	1.98	7.78e-03	3.41e-02	33
GO:0060412	GO:0060412	ventricular septum morphogenesis	13/1669	33/8380	1.98	7.78e-03	3.41e-02	33
GO:1900274	GO:1900274	regulation of phospholipase C activity	13/1669	33/8380	1.98	7.78e-03	3.41e-02	33
GO:1903727	GO:1903727	positive regulation of phospholipid metabolic process	13/1669	33/8380	1.98	7.78e-03	3.41e-02	33
GO:0030510	GO:0030510	regulation of BMP signaling pathway	19/1669	55/8380	1.73	7.79e-03	3.41e-02	55
GO:0048708	GO:0048708	astrocyte differentiation	19/1669	55/8380	1.73	7.79e-03	3.41e-02	55
GO:0007585	GO:0007585	respiratory gaseous exchange	16/1669	44/8380	1.83	8.17e-03	3.54e-02	44
GO:0014910	GO:0014910	regulation of smooth muscle cell migration	16/1669	44/8380	1.83	8.17e-03	3.54e-02	44
GO:0051492	GO:0051492	regulation of stress fiber assembly	16/1669	44/8380	1.83	8.17e-03	3.54e-02	44
GO:0051953	GO:0051953	negative regulation of amine transport	10/1669	23/8380	2.18	8.59e-03	3.69e-02	23
GO:0061037	GO:0061037	negative regulation of cartilage development	10/1669	23/8380	2.18	8.59e-03	3.69e-02	23
GO:1900015	GO:1900015	regulation of cytokine production involved in inflammatory response	10/1669	23/8380	2.18	8.59e-03	3.69e-02	23
GO:0030168	GO:0030168	platelet activation	31/1669	103/8380	1.51	8.68e-03	3.72e-02	103
GO:0034763	GO:0034763	negative regulation of transmembrane transport	23/1669	71/8380	1.63	8.74e-03	3.72e-02	71
GO:0048144	GO:0048144	fibroblast proliferation	17/1669	48/8380	1.78	8.76e-03	3.72e-02	48
GO:0048844	GO:0048844	artery morphogenesis	17/1669	48/8380	1.78	8.76e-03	3.72e-02	48
GO:0050432	GO:0050432	catecholamine secretion	17/1669	48/8380	1.78	8.76e-03	3.72e-02	48
GO:0050433	GO:0050433	regulation of catecholamine secretion	17/1669	48/8380	1.78	8.76e-03	3.72e-02	48
GO:0032233	GO:0032233	positive regulation of actin filament bundle assembly	14/1669	37/8380	1.90	8.80e-03	3.72e-02	37
GO:0044060	GO:0044060	regulation of endocrine process	14/1669	37/8380	1.90	8.80e-03	3.72e-02	37
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	24/1669	75/8380	1.61	8.84e-03	3.72e-02	75
GO:1904892	GO:1904892	regulation of STAT cascade	24/1669	75/8380	1.61	8.84e-03	3.72e-02	75
GO:0051147	GO:0051147	regulation of muscle cell differentiation	28/1669	91/8380	1.54	8.90e-03	3.74e-02	91
GO:0097696	GO:0097696	STAT cascade	26/1669	83/8380	1.57	8.94e-03	3.75e-02	83
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	12/1669	30/8380	2.01	9.06e-03	3.79e-02	30
GO:0032835	GO:0032835	glomerulus development	18/1669	52/8380	1.74	9.24e-03	3.86e-02	52
GO:0002691	GO:0002691	regulation of cellular extravasation	9/1669	20/8380	2.26	9.63e-03	4.00e-02	20
GO:0035929	GO:0035929	steroid hormone secretion	9/1669	20/8380	2.26	9.63e-03	4.00e-02	20
GO:0048011	GO:0048011	neurotrophin TRK receptor signaling pathway	9/1669	20/8380	2.26	9.63e-03	4.00e-02	20
GO:1903792	GO:1903792	negative regulation of anion transport	9/1669	20/8380	2.26	9.63e-03	4.00e-02	20
GO:0032370	GO:0032370	positive regulation of lipid transport	15/1669	41/8380	1.84	9.66e-03	4.00e-02	41
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	15/1669	41/8380	1.84	9.66e-03	4.00e-02	41
GO:0071385	GO:0071385	cellular response to glucocorticoid stimulus	15/1669	41/8380	1.84	9.66e-03	4.00e-02	41
GO:0030316	GO:0030316	osteoclast differentiation	20/1669	60/8380	1.67	9.95e-03	4.10e-02	60
GO:1903035	GO:1903035	negative regulation of response to wounding	20/1669	60/8380	1.67	9.95e-03	4.10e-02	60
GO:1990748	GO:1990748	cellular detoxification	20/1669	60/8380	1.67	9.95e-03	4.10e-02	60
GO:0035987	GO:0035987	endodermal cell differentiation	13/1669	34/8380	1.92	1.03e-02	4.21e-02	34
GO:0045776	GO:0045776	negative regulation of blood pressure	13/1669	34/8380	1.92	1.03e-02	4.21e-02	34
GO:1903391	GO:1903391	regulation of adherens junction organization	13/1669	34/8380	1.92	1.03e-02	4.21e-02	34
GO:0015844	GO:0015844	monoamine transport	22/1669	68/8380	1.62	1.04e-02	4.21e-02	68
GO:0048644	GO:0048644	muscle organ morphogenesis	22/1669	68/8380	1.62	1.04e-02	4.21e-02	68
GO:0030177	GO:0030177	positive regulation of Wnt signaling pathway	23/1669	72/8380	1.60	1.05e-02	4.21e-02	72
GO:0046425	GO:0046425	regulation of JAK-STAT cascade	23/1669	72/8380	1.60	1.05e-02	4.21e-02	72
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	23/1669	72/8380	1.60	1.05e-02	4.21e-02	72
GO:0051154	GO:0051154	negative regulation of striated muscle cell differentiation	11/1669	27/8380	2.05	1.05e-02	4.21e-02	27
GO:0006766	GO:0006766	vitamin metabolic process	24/1669	76/8380	1.59	1.05e-02	4.21e-02	76
GO:0045667	GO:0045667	regulation of osteoblast differentiation	24/1669	76/8380	1.59	1.05e-02	4.21e-02	76
GO:0006720	GO:0006720	isoprenoid metabolic process	26/1669	84/8380	1.55	1.06e-02	4.21e-02	84
GO:0055088	GO:0055088	lipid homeostasis	26/1669	84/8380	1.55	1.06e-02	4.21e-02	84
GO:0060349	GO:0060349	bone morphogenesis	26/1669	84/8380	1.55	1.06e-02	4.21e-02	84
GO:0007259	GO:0007259	JAK-STAT cascade	25/1669	80/8380	1.57	1.06e-02	4.21e-02	80
GO:1903825	GO:1903825	organic acid transmembrane transport	25/1669	80/8380	1.57	1.06e-02	4.21e-02	80
GO:1905039	GO:1905039	carboxylic acid transmembrane transport	25/1669	80/8380	1.57	1.06e-02	4.21e-02	80
GO:0001893	GO:0001893	maternal placenta development	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0003016	GO:0003016	respiratory system process	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0003181	GO:0003181	atrioventricular valve morphogenesis	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0003298	GO:0003298	physiological muscle hypertrophy	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0003301	GO:0003301	physiological cardiac muscle hypertrophy	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0009595	GO:0009595	detection of biotic stimulus	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0014821	GO:0014821	phasic smooth muscle contraction	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0014912	GO:0014912	negative regulation of smooth muscle cell migration	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0061049	GO:0061049	cell growth involved in cardiac muscle cell development	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0071875	GO:0071875	adrenergic receptor signaling pathway	8/1669	17/8380	2.36	1.06e-02	4.21e-02	17
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	17/1669	49/8380	1.74	1.10e-02	4.34e-02	49
GO:0031280	GO:0031280	negative regulation of cyclase activity	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0043576	GO:0043576	regulation of respiratory gaseous exchange	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0048384	GO:0048384	retinoic acid receptor signaling pathway	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0051894	GO:0051894	positive regulation of focal adhesion assembly	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0060713	GO:0060713	labyrinthine layer morphogenesis	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0061298	GO:0061298	retina vasculature development in camera-type eye	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0070293	GO:0070293	renal absorption	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0098581	GO:0098581	detection of external biotic stimulus	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:1905476	GO:1905476	negative regulation of protein localization to membrane	7/1669	14/8380	2.51	1.13e-02	4.41e-02	14
GO:0003214	GO:0003214	cardiac left ventricle morphogenesis	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0042574	GO:0042574	retinal metabolic process	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0044144	GO:0044144	modulation of growth of symbiont involved in interaction with host	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0044146	GO:0044146	negative regulation of growth of symbiont involved in interaction with host	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0051023	GO:0051023	regulation of immunoglobulin secretion	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0070493	GO:0070493	thrombin-activated receptor signaling pathway	6/1669	11/8380	2.74	1.14e-02	4.41e-02	11
GO:0002063	GO:0002063	chondrocyte development	14/1669	38/8380	1.85	1.14e-02	4.42e-02	38
GO:0060393	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	14/1669	38/8380	1.85	1.14e-02	4.42e-02	38
GO:0019226	GO:0019226	transmission of nerve impulse	18/1669	53/8380	1.71	1.15e-02	4.43e-02	53
GO:0006606	GO:0006606	protein import into nucleus	19/1669	57/8380	1.67	1.18e-02	4.54e-02	57
GO:0002028	GO:0002028	regulation of sodium ion transport	20/1669	61/8380	1.65	1.21e-02	4.57e-02	61
GO:0022617	GO:0022617	extracellular matrix disassembly	20/1669	61/8380	1.65	1.21e-02	4.57e-02	61
GO:2000379	GO:2000379	positive regulation of reactive oxygen species metabolic process	20/1669	61/8380	1.65	1.21e-02	4.57e-02	61
GO:0003230	GO:0003230	cardiac atrium development	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:0030224	GO:0030224	monocyte differentiation	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:0038179	GO:0038179	neurotrophin signaling pathway	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:0072677	GO:0072677	eosinophil migration	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:1902622	GO:1902622	regulation of neutrophil migration	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:1903131	GO:1903131	mononuclear cell differentiation	10/1669	24/8380	2.09	1.21e-02	4.57e-02	24
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	28/1669	93/8380	1.51	1.22e-02	4.57e-02	93
GO:0001504	GO:0001504	neurotransmitter uptake	12/1669	31/8380	1.94	1.22e-02	4.57e-02	31
GO:0051930	GO:0051930	regulation of sensory perception of pain	12/1669	31/8380	1.94	1.22e-02	4.57e-02	31
GO:0060043	GO:0060043	regulation of cardiac muscle cell proliferation	12/1669	31/8380	1.94	1.22e-02	4.57e-02	31
GO:0086010	GO:0086010	membrane depolarization during action potential	12/1669	31/8380	1.94	1.22e-02	4.57e-02	31
GO:1900182	GO:1900182	positive regulation of protein localization to nucleus	12/1669	31/8380	1.94	1.22e-02	4.57e-02	31
GO:0048634	GO:0048634	regulation of muscle organ development	27/1669	89/8380	1.52	1.23e-02	4.62e-02	89
GO:0019218	GO:0019218	regulation of steroid metabolic process	22/1669	69/8380	1.60	1.24e-02	4.65e-02	69
GO:0071901	GO:0071901	negative regulation of protein serine/threonine kinase activity	22/1669	69/8380	1.60	1.24e-02	4.65e-02	69
GO:0016999	GO:0016999	antibiotic metabolic process	25/1669	81/8380	1.55	1.25e-02	4.67e-02	81
GO:0002495	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	16/1669	46/8380	1.75	1.30e-02	4.85e-02	46
GO:0006801	GO:0006801	superoxide metabolic process	16/1669	46/8380	1.75	1.30e-02	4.85e-02	46
GO:0019319	GO:0019319	hexose biosynthetic process	16/1669	46/8380	1.75	1.30e-02	4.85e-02	46
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	16/1669	46/8380	1.75	1.30e-02	4.85e-02	46
GO:0060193	GO:0060193	positive regulation of lipase activity	16/1669	46/8380	1.75	1.30e-02	4.85e-02	46
GO:0032653	GO:0032653	regulation of interleukin-10 production	13/1669	35/8380	1.86	1.35e-02	5.00e-02	35
GO:0090303	GO:0090303	positive regulation of wound healing	13/1669	35/8380	1.86	1.35e-02	5.00e-02	35
GO:1905207	GO:1905207	regulation of cardiocyte differentiation	13/1669	35/8380	1.86	1.35e-02	5.00e-02	35

Factor 15 : 2 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0018149	GO:0018149	peptide cross-linking	27/3218	38/8380	1.85	4.40e-05	0.0297	38
GO:0070268	GO:0070268	cornification	55/3218	95/8380	1.51	8.47e-05	0.0401	95

Factor 16 : 614 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0002250	GO:0002250	adaptive immune response	153/1988	270/8380	2.39	3.19e-32	1.25e-28	270
GO:0050778	GO:0050778	positive regulation of immune response	214/1988	443/8380	2.04	3.47e-31	6.83e-28	443
GO:0046649	GO:0046649	lymphocyte activation	204/1988	416/8380	2.07	7.40e-31	9.70e-28	416
GO:0002443	GO:0002443	leukocyte mediated immunity	204/1988	435/8380	1.98	1.48e-27	1.46e-24	435
GO:0002366	GO:0002366	leukocyte activation involved in immune response	183/1988	378/8380	2.04	7.92e-27	5.43e-24	378
GO:0002263	GO:0002263	cell activation involved in immune response	184/1988	381/8380	2.04	8.29e-27	5.43e-24	381
GO:0050865	GO:0050865	regulation of cell activation	176/1988	362/8380	2.05	4.33e-26	2.43e-23	362
GO:0002694	GO:0002694	regulation of leukocyte activation	166/1988	334/8380	2.10	5.41e-26	2.66e-23	334
GO:0002274	GO:0002274	myeloid leukocyte activation	173/1988	362/8380	2.01	1.42e-24	6.21e-22	362
GO:0042110	GO:0042110	T cell activation	152/1988	306/8380	2.09	8.04e-24	3.16e-21	306
GO:0002764	GO:0002764	immune response-regulating signaling pathway	146/1988	291/8380	2.11	1.84e-23	6.40e-21	291
GO:0002757	GO:0002757	immune response-activating signal transduction	138/1988	269/8380	2.16	2.11e-23	6.40e-21	269
GO:0001816	GO:0001816	cytokine production	203/1988	459/8380	1.86	2.12e-23	6.40e-21	459
GO:0002253	GO:0002253	activation of immune response	156/1988	321/8380	2.05	3.65e-23	1.02e-20	321
GO:0051249	GO:0051249	regulation of lymphocyte activation	139/1988	276/8380	2.12	1.42e-22	3.72e-20	276
GO:0031347	GO:0031347	regulation of defense response	194/1988	445/8380	1.84	1.74e-21	4.27e-19	445
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	200/1988	465/8380	1.81	2.73e-21	6.31e-19	465
GO:0001817	GO:0001817	regulation of cytokine production	180/1988	415/8380	1.83	1.10e-19	2.41e-17	415
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	138/1988	291/8380	2.00	2.26e-19	4.45e-17	291
GO:0002697	GO:0002697	regulation of immune effector process	123/1988	248/8380	2.09	2.26e-19	4.45e-17	248
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	116/1988	231/8380	2.12	7.19e-19	1.35e-16	231
GO:0050867	GO:0050867	positive regulation of cell activation	112/1988	220/8380	2.15	7.66e-19	1.37e-16	220
GO:0002521	GO:0002521	leukocyte differentiation	146/1988	320/8380	1.92	1.67e-18	2.85e-16	320
GO:0050863	GO:0050863	regulation of T cell activation	110/1988	217/8380	2.14	2.41e-18	3.95e-16	217
GO:0043299	GO:0043299	leukocyte degranulation	133/1988	283/8380	1.98	2.76e-18	4.35e-16	283
GO:0002696	GO:0002696	positive regulation of leukocyte activation	108/1988	212/8380	2.15	3.09e-18	4.67e-16	212
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	134/1988	290/8380	1.95	1.24e-17	1.80e-15	290
GO:0036230	GO:0036230	granulocyte activation	124/1988	263/8380	1.99	2.96e-17	4.15e-15	263
GO:0045088	GO:0045088	regulation of innate immune response	107/1988	215/8380	2.10	3.95e-17	5.36e-15	215
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	94/1988	180/8380	2.20	6.19e-17	8.12e-15	180
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	103/1988	207/8380	2.10	1.59e-16	2.01e-14	207
GO:0042119	GO:0042119	neutrophil activation	121/1988	260/8380	1.96	2.55e-16	3.14e-14	260
GO:0030098	GO:0030098	lymphocyte differentiation	106/1988	217/8380	2.06	2.99e-16	3.56e-14	217
GO:0002283	GO:0002283	neutrophil activation involved in immune response	118/1988	252/8380	1.97	3.43e-16	3.96e-14	252
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	102/1988	207/8380	2.08	5.24e-16	5.88e-14	207
GO:0050870	GO:0050870	positive regulation of T cell activation	80/1988	147/8380	2.29	6.12e-16	6.65e-14	147
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	94/1988	185/8380	2.14	6.26e-16	6.65e-14	185
GO:0009615	GO:0009615	response to virus	85/1988	161/8380	2.23	8.43e-16	8.72e-14	161
GO:0043312	GO:0043312	neutrophil degranulation	116/1988	249/8380	1.96	9.88e-16	9.96e-14	249
GO:0002446	GO:0002446	neutrophil mediated immunity	118/1988	256/8380	1.94	1.48e-15	1.45e-13	256
GO:0001819	GO:0001819	positive regulation of cytokine production	124/1988	274/8380	1.91	1.56e-15	1.50e-13	274
GO:0031349	GO:0031349	positive regulation of defense response	124/1988	275/8380	1.90	2.20e-15	2.06e-13	275
GO:0030097	GO:0030097	hemopoiesis	188/1988	477/8380	1.66	2.80e-15	2.56e-13	477
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	82/1988	157/8380	2.20	6.19e-15	5.53e-13	157
GO:0051607	GO:0051607	defense response to virus	66/1988	115/8380	2.42	6.91e-15	6.04e-13	115
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	86/1988	172/8380	2.11	3.72e-14	3.18e-12	172
GO:0045089	GO:0045089	positive regulation of innate immune response	90/1988	184/8380	2.06	5.04e-14	4.22e-12	184
GO:0034341	GO:0034341	response to interferon-gamma	72/1988	135/8380	2.25	7.11e-14	5.82e-12	135
GO:0030217	GO:0030217	T cell differentiation	81/1988	162/8380	2.11	2.09e-13	1.68e-11	162
GO:0098542	GO:0098542	defense response to other organism	114/1988	259/8380	1.86	2.39e-13	1.88e-11	259
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	89/1988	186/8380	2.02	3.52e-13	2.72e-11	186
GO:0022407	GO:0022407	regulation of cell-cell adhesion	119/1988	276/8380	1.82	4.07e-13	3.07e-11	276
GO:0042113	GO:0042113	B cell activation	69/1988	131/8380	2.22	5.28e-13	3.91e-11	131
GO:0070661	GO:0070661	leukocyte proliferation	92/1988	196/8380	1.98	5.79e-13	4.22e-11	196
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	64/1988	118/8380	2.29	6.39e-13	4.57e-11	118
GO:0002699	GO:0002699	positive regulation of immune effector process	72/1988	141/8380	2.15	1.23e-12	8.63e-11	141
GO:0060337	GO:0060337	type I interferon signaling pathway	36/1988	51/8380	2.98	1.67e-12	1.13e-10	51
GO:0071357	GO:0071357	cellular response to type I interferon	36/1988	51/8380	2.98	1.67e-12	1.13e-10	51
GO:0002683	GO:0002683	negative regulation of immune system process	120/1988	284/8380	1.78	1.74e-12	1.16e-10	284
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	69/1988	134/8380	2.17	2.18e-12	1.43e-10	134
GO:0070663	GO:0070663	regulation of leukocyte proliferation	79/1988	162/8380	2.06	2.22e-12	1.43e-10	162
GO:0050727	GO:0050727	regulation of inflammatory response	109/1988	251/8380	1.83	2.35e-12	1.49e-10	251
GO:0046631	GO:0046631	alpha-beta T cell activation	55/1988	97/8380	2.39	2.48e-12	1.55e-10	97
GO:0032943	GO:0032943	mononuclear cell proliferation	86/1988	183/8380	1.98	3.09e-12	1.90e-10	183
GO:0034340	GO:0034340	response to type I interferon	36/1988	52/8380	2.92	4.20e-12	2.54e-10	52
GO:0002449	GO:0002449	lymphocyte mediated immunity	78/1988	161/8380	2.04	4.69e-12	2.79e-10	161
GO:0045055	GO:0045055	regulated exocytosis	172/1988	460/8380	1.58	1.01e-11	5.90e-10	460
GO:0071346	GO:0071346	cellular response to interferon-gamma	63/1988	121/8380	2.19	1.06e-11	6.15e-10	121
GO:0046651	GO:0046651	lymphocyte proliferation	84/1988	181/8380	1.96	1.27e-11	7.25e-10	181
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	75/1988	156/8380	2.03	1.95e-11	1.09e-09	156
GO:0030155	GO:0030155	regulation of cell adhesion	170/1988	458/8380	1.56	2.70e-11	1.49e-09	458
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	74/1988	155/8380	2.01	4.05e-11	2.21e-09	155
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	53/1988	97/8380	2.30	4.30e-11	2.31e-09	97
GO:0032609	GO:0032609	interferon-gamma production	49/1988	87/8380	2.37	5.45e-11	2.89e-09	87
GO:0002758	GO:0002758	innate immune response-activating signal transduction	66/1988	133/8380	2.09	5.55e-11	2.91e-09	133
GO:0002695	GO:0002695	negative regulation of leukocyte activation	58/1988	111/8380	2.20	5.85e-11	3.02e-09	111
GO:0050853	GO:0050853	B cell receptor signaling pathway	29/1988	40/8380	3.06	8.89e-11	4.54e-09	40
GO:0050663	GO:0050663	cytokine secretion	71/1988	149/8380	2.01	1.13e-10	5.68e-09	149
GO:0002819	GO:0002819	regulation of adaptive immune response	56/1988	107/8380	2.21	1.16e-10	5.75e-09	107
GO:0045785	GO:0045785	positive regulation of cell adhesion	116/1988	287/8380	1.70	1.26e-10	6.18e-09	287
GO:0002218	GO:0002218	activation of innate immune response	67/1988	138/8380	2.05	1.36e-10	6.59e-09	138
GO:1902105	GO:1902105	regulation of leukocyte differentiation	81/1988	179/8380	1.91	1.43e-10	6.85e-09	179
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	29/1988	41/8380	2.98	2.35e-10	1.10e-08	41
GO:0050866	GO:0050866	negative regulation of cell activation	63/1988	128/8380	2.07	2.36e-10	1.10e-08	128
GO:0050900	GO:0050900	leukocyte migration	125/1988	319/8380	1.65	2.61e-10	1.21e-08	319
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	51/1988	96/8380	2.24	3.88e-10	1.78e-08	96
GO:0032649	GO:0032649	regulation of interferon-gamma production	44/1988	78/8380	2.38	4.90e-10	2.21e-08	78
GO:0032103	GO:0032103	positive regulation of response to external stimulus	89/1988	208/8380	1.80	6.43e-10	2.87e-08	208
GO:0046632	GO:0046632	alpha-beta T cell differentiation	41/1988	71/8380	2.43	7.24e-10	3.20e-08	71
GO:0043900	GO:0043900	regulation of multi-organism process	83/1988	191/8380	1.83	9.91e-10	4.33e-08	191
GO:0009617	GO:0009617	response to bacterium	146/1988	395/8380	1.56	1.05e-09	4.53e-08	395
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	56/1988	112/8380	2.11	1.11e-09	4.75e-08	112
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	39/1988	67/8380	2.45	1.37e-09	5.72e-08	67
GO:0002224	GO:0002224	toll-like receptor signaling pathway	42/1988	75/8380	2.36	1.65e-09	6.83e-08	75
GO:0050864	GO:0050864	regulation of B cell activation	41/1988	73/8380	2.37	2.29e-09	9.38e-08	73
GO:0006909	GO:0006909	phagocytosis	66/1988	143/8380	1.95	2.71e-09	1.10e-07	143
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	38/1988	66/8380	2.43	3.42e-09	1.36e-07	66
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	38/1988	66/8380	2.43	3.42e-09	1.36e-07	66
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	50/1988	98/8380	2.15	3.60e-09	1.41e-07	98
GO:0045071	GO:0045071	negative regulation of viral genome replication	23/1988	31/8380	3.13	3.96e-09	1.54e-07	31
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	49/1988	96/8380	2.15	5.06e-09	1.95e-07	96
GO:0001818	GO:0001818	negative regulation of cytokine production	74/1988	169/8380	1.85	5.40e-09	2.06e-07	169
GO:1903706	GO:1903706	regulation of hemopoiesis	100/1988	251/8380	1.68	6.10e-09	2.31e-07	251
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	61/1988	131/8380	1.96	7.11e-09	2.66e-07	131
GO:0002821	GO:0002821	positive regulation of adaptive immune response	39/1988	70/8380	2.35	7.69e-09	2.85e-07	70
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	49/1988	97/8380	2.13	7.90e-09	2.90e-07	97
GO:0042102	GO:0042102	positive regulation of T cell proliferation	42/1988	78/8380	2.27	8.11e-09	2.95e-07	78
GO:0002440	GO:0002440	production of molecular mediator of immune response	55/1988	114/8380	2.03	8.17e-09	2.95e-07	114
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	50/1988	100/8380	2.11	8.67e-09	3.10e-07	100
GO:0006897	GO:0006897	endocytosis	143/1988	396/8380	1.52	9.35e-09	3.31e-07	396
GO:0055065	GO:0055065	metal ion homeostasis	152/1988	427/8380	1.50	9.58e-09	3.36e-07	427
GO:0071216	GO:0071216	cellular response to biotic stimulus	63/1988	138/8380	1.92	1.06e-08	3.67e-07	138
GO:0031295	GO:0031295	T cell costimulation	26/1988	39/8380	2.81	1.46e-08	5.00e-07	39
GO:0019058	GO:0019058	viral life cycle	62/1988	136/8380	1.92	1.48e-08	5.00e-07	136
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	52/1988	107/8380	2.05	1.52e-08	5.12e-07	107
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	47/1988	93/8380	2.13	1.57e-08	5.22e-07	93
GO:0002286	GO:0002286	T cell activation involved in immune response	35/1988	61/8380	2.42	1.61e-08	5.31e-07	61
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	31/1988	51/8380	2.56	1.62e-08	5.31e-07	51
GO:0042100	GO:0042100	B cell proliferation	33/1988	56/8380	2.48	1.67e-08	5.42e-07	56
GO:0050707	GO:0050707	regulation of cytokine secretion	59/1988	128/8380	1.94	2.00e-08	6.39e-07	128
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	51/1988	105/8380	2.05	2.14e-08	6.80e-07	105
GO:0019882	GO:0019882	antigen processing and presentation	47/1988	94/8380	2.11	2.42e-08	7.61e-07	94
GO:0042129	GO:0042129	regulation of T cell proliferation	54/1988	114/8380	2.00	2.49e-08	7.77e-07	114
GO:0031294	GO:0031294	lymphocyte costimulation	26/1988	40/8380	2.74	3.24e-08	1.00e-06	40
GO:0030595	GO:0030595	leukocyte chemotaxis	73/1988	172/8380	1.79	3.39e-08	1.03e-06	172
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	46/1988	92/8380	2.11	3.41e-08	1.03e-06	92
GO:0045580	GO:0045580	regulation of T cell differentiation	46/1988	92/8380	2.11	3.41e-08	1.03e-06	92
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	28/1988	45/8380	2.62	3.91e-08	1.17e-06	45
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	50/1988	104/8380	2.03	4.49e-08	1.34e-06	104
GO:0002237	GO:0002237	response to molecule of bacterial origin	89/1988	224/8380	1.67	4.91e-08	1.45e-06	224
GO:0045069	GO:0045069	regulation of viral genome replication	27/1988	43/8380	2.65	5.19e-08	1.52e-06	43
GO:0032640	GO:0032640	tumor necrosis factor production	46/1988	93/8380	2.08	5.21e-08	1.52e-06	93
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	58/1988	128/8380	1.91	5.61e-08	1.62e-06	128
GO:0019079	GO:0019079	viral genome replication	31/1988	53/8380	2.47	5.79e-08	1.66e-06	53
GO:0050729	GO:0050729	positive regulation of inflammatory response	48/1988	99/8380	2.04	5.97e-08	1.70e-06	99
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	36/1988	66/8380	2.30	6.09e-08	1.72e-06	66
GO:0060326	GO:0060326	cell chemotaxis	89/1988	225/8380	1.67	6.27e-08	1.76e-06	225
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	34/1988	61/8380	2.35	6.94e-08	1.94e-06	61
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	57/1988	126/8380	1.91	7.84e-08	2.17e-06	126
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	25/1988	39/8380	2.70	9.01e-08	2.46e-06	39
GO:0043901	GO:0043901	negative regulation of multi-organism process	44/1988	89/8380	2.08	1.03e-07	2.78e-06	89
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	46/1988	95/8380	2.04	1.18e-07	3.14e-06	95
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	43/1988	87/8380	2.08	1.45e-07	3.81e-06	87
GO:0002698	GO:0002698	negative regulation of immune effector process	36/1988	68/8380	2.23	1.67e-07	4.36e-06	68
GO:0016032	GO:0016032	viral process	98/1988	259/8380	1.59	1.76e-07	4.56e-06	259
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	37/1988	71/8380	2.20	1.92e-07	4.94e-06	71
GO:1903900	GO:1903900	regulation of viral life cycle	34/1988	63/8380	2.27	2.00e-07	5.11e-06	63
GO:0042098	GO:0042098	T cell proliferation	57/1988	129/8380	1.86	2.11e-07	5.36e-06	129
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	32/1988	58/8380	2.33	2.32e-07	5.85e-06	58
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	46/1988	97/8380	2.00	2.57e-07	6.45e-06	97
GO:0071887	GO:0071887	leukocyte apoptotic process	36/1988	69/8380	2.20	2.71e-07	6.74e-06	69
GO:0042089	GO:0042089	cytokine biosynthetic process	37/1988	72/8380	2.17	3.06e-07	7.57e-06	72
GO:0035455	GO:0035455	response to interferon-alpha	12/1988	13/8380	3.89	3.15e-07	7.74e-06	13
GO:0050777	GO:0050777	negative regulation of immune response	43/1988	89/8380	2.04	3.29e-07	8.03e-06	89
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	40/1988	81/8380	2.08	4.06e-07	9.85e-06	81
GO:0044403	GO:0044403	symbiont process	106/1988	290/8380	1.54	4.16e-07	1.00e-05	290
GO:0031341	GO:0031341	regulation of cell killing	36/1988	70/8380	2.17	4.31e-07	1.03e-05	70
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	30/1988	54/8380	2.34	4.52e-07	1.07e-05	54
GO:0050852	GO:0050852	T cell receptor signaling pathway	42/1988	87/8380	2.03	4.62e-07	1.09e-05	87
GO:0032496	GO:0032496	response to lipopolysaccharide	83/1988	214/8380	1.63	4.68e-07	1.10e-05	214
GO:0042107	GO:0042107	cytokine metabolic process	37/1988	73/8380	2.14	4.80e-07	1.12e-05	73
GO:1903901	GO:1903901	negative regulation of viral life cycle	24/1988	39/8380	2.59	4.99e-07	1.15e-05	39
GO:0030888	GO:0030888	regulation of B cell proliferation	26/1988	44/8380	2.49	5.19e-07	1.19e-05	44
GO:0045582	GO:0045582	positive regulation of T cell differentiation	31/1988	57/8380	2.29	5.50e-07	1.26e-05	57
GO:0019724	GO:0019724	B cell mediated immunity	35/1988	68/8380	2.17	6.07e-07	1.38e-05	68
GO:0031343	GO:0031343	positive regulation of cell killing	29/1988	52/8380	2.35	6.30e-07	1.41e-05	52
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	29/1988	52/8380	2.35	6.30e-07	1.41e-05	52
GO:0097028	GO:0097028	dendritic cell differentiation	20/1988	30/8380	2.81	7.08e-07	1.58e-05	30
GO:1903708	GO:1903708	positive regulation of hemopoiesis	52/1988	118/8380	1.86	7.93e-07	1.76e-05	118
GO:0002367	GO:0002367	cytokine production involved in immune response	34/1988	66/8380	2.17	8.55e-07	1.89e-05	66
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	40/1988	83/8380	2.03	9.15e-07	2.00e-05	83
GO:0002292	GO:0002292	T cell differentiation involved in immune response	26/1988	45/8380	2.44	9.52e-07	2.07e-05	45
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	18/1988	26/8380	2.92	1.11e-06	2.39e-05	26
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	21/1988	33/8380	2.68	1.18e-06	2.51e-05	33
GO:0032655	GO:0032655	regulation of interleukin-12 production	21/1988	33/8380	2.68	1.18e-06	2.51e-05	33
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	33/1988	64/8380	2.17	1.20e-06	2.55e-05	64
GO:0016064	GO:0016064	immunoglobulin mediated immune response	34/1988	67/8380	2.14	1.34e-06	2.83e-05	67
GO:0050868	GO:0050868	negative regulation of T cell activation	35/1988	70/8380	2.11	1.48e-06	3.09e-05	70
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	43/1988	93/8380	1.95	1.49e-06	3.10e-05	93
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	50/1988	114/8380	1.85	1.53e-06	3.16e-05	114
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	32/1988	62/8380	2.18	1.70e-06	3.46e-05	62
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	32/1988	62/8380	2.18	1.70e-06	3.46e-05	62
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	26/1988	46/8380	2.38	1.70e-06	3.46e-05	46
GO:0097529	GO:0097529	myeloid leukocyte migration	64/1988	158/8380	1.71	1.71e-06	3.47e-05	158
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	24/1988	41/8380	2.47	1.81e-06	3.61e-05	41
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	24/1988	41/8380	2.47	1.81e-06	3.61e-05	41
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	24/1988	41/8380	2.47	1.81e-06	3.61e-05	41
GO:0050869	GO:0050869	negative regulation of B cell activation	15/1988	20/8380	3.16	1.82e-06	3.61e-05	20
GO:0050688	GO:0050688	regulation of defense response to virus	19/1988	29/8380	2.76	2.02e-06	3.99e-05	29
GO:0045807	GO:0045807	positive regulation of endocytosis	41/1988	88/8380	1.96	2.04e-06	4.00e-05	88
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	86/1988	231/8380	1.57	2.18e-06	4.27e-05	231
GO:0032615	GO:0032615	interleukin-12 production	21/1988	34/8380	2.60	2.40e-06	4.65e-05	34
GO:0050792	GO:0050792	regulation of viral process	37/1988	77/8380	2.03	2.55e-06	4.91e-05	77
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	39/1988	83/8380	1.98	2.77e-06	5.31e-05	83
GO:0030100	GO:0030100	regulation of endocytosis	59/1988	144/8380	1.73	2.80e-06	5.33e-05	144
GO:0032635	GO:0032635	interleukin-6 production	40/1988	86/8380	1.96	2.85e-06	5.39e-05	86
GO:0002831	GO:0002831	regulation of response to biotic stimulus	33/1988	66/8380	2.11	2.93e-06	5.48e-05	66
GO:0006968	GO:0006968	cellular defense response	26/1988	47/8380	2.33	2.95e-06	5.48e-05	47
GO:0048525	GO:0048525	negative regulation of viral process	26/1988	47/8380	2.33	2.95e-06	5.48e-05	47
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	29/1988	55/8380	2.22	2.96e-06	5.48e-05	55
GO:0042088	GO:0042088	T-helper 1 type immune response	20/1988	32/8380	2.63	3.22e-06	5.91e-05	32
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	20/1988	32/8380	2.63	3.22e-06	5.91e-05	32
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	24/1988	42/8380	2.41	3.28e-06	5.98e-05	42
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	17/1988	25/8380	2.87	3.29e-06	5.98e-05	25
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	37/1988	78/8380	2.00	3.75e-06	6.73e-05	78
GO:0043368	GO:0043368	positive T cell selection	16/1988	23/8380	2.93	4.09e-06	7.31e-05	23
GO:0032623	GO:0032623	interleukin-2 production	25/1988	45/8380	2.34	4.12e-06	7.33e-05	45
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	23/1988	40/8380	2.42	4.54e-06	8.01e-05	40
GO:0002886	GO:0002886	regulation of myeloid leukocyte mediated immunity	21/1988	35/8380	2.53	4.66e-06	8.18e-05	35
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	10/1988	11/8380	3.83	4.79e-06	8.34e-05	11
GO:1903587	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	10/1988	11/8380	3.83	4.79e-06	8.34e-05	11
GO:0098586	GO:0098586	cellular response to virus	15/1988	21/8380	3.01	4.96e-06	8.59e-05	21
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	93/1988	259/8380	1.51	5.08e-06	8.77e-05	259
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	47/1988	109/8380	1.82	5.53e-06	9.41e-05	109
GO:0002507	GO:0002507	tolerance induction	14/1988	19/8380	3.11	5.81e-06	9.84e-05	19
GO:0002573	GO:0002573	myeloid leukocyte differentiation	54/1988	131/8380	1.74	5.90e-06	9.96e-05	131
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	22/1988	38/8380	2.44	6.29e-06	1.05e-04	38
GO:0045058	GO:0045058	T cell selection	20/1988	33/8380	2.55	6.35e-06	1.06e-04	33
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	28/1988	54/8380	2.19	6.70e-06	1.11e-04	54
GO:0035456	GO:0035456	response to interferon-beta	12/1988	15/8380	3.37	6.75e-06	1.12e-04	15
GO:0048771	GO:0048771	tissue remodeling	47/1988	110/8380	1.80	7.46e-06	1.22e-04	110
GO:0007259	GO:0007259	JAK-STAT cascade	37/1988	80/8380	1.95	7.86e-06	1.28e-04	80
GO:0032675	GO:0032675	regulation of interleukin-6 production	37/1988	80/8380	1.95	7.86e-06	1.28e-04	80
GO:0097696	GO:0097696	STAT cascade	38/1988	83/8380	1.93	8.01e-06	1.30e-04	83
GO:0050715	GO:0050715	positive regulation of cytokine secretion	40/1988	89/8380	1.89	8.14e-06	1.31e-04	89
GO:0002377	GO:0002377	immunoglobulin production	26/1988	49/8380	2.24	8.25e-06	1.31e-04	49
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	26/1988	49/8380	2.24	8.25e-06	1.31e-04	49
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	26/1988	49/8380	2.24	8.25e-06	1.31e-04	49
GO:0006911	GO:0006911	phagocytosis, engulfment	19/1988	31/8380	2.58	8.61e-06	1.36e-04	31
GO:0071674	GO:0071674	mononuclear cell migration	33/1988	69/8380	2.02	1.00e-05	1.57e-04	69
GO:0050764	GO:0050764	regulation of phagocytosis	28/1988	55/8380	2.15	1.06e-05	1.65e-04	55
GO:0006869	GO:0006869	lipid transport	83/1988	229/8380	1.53	1.09e-05	1.69e-04	229
GO:1903317	GO:1903317	regulation of protein maturation	36/1988	78/8380	1.95	1.10e-05	1.71e-04	78
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	40/1988	90/8380	1.87	1.13e-05	1.75e-04	90
GO:0006898	GO:0006898	receptor-mediated endocytosis	70/1988	186/8380	1.59	1.25e-05	1.90e-04	186
GO:0030099	GO:0030099	myeloid cell differentiation	81/1988	223/8380	1.53	1.26e-05	1.92e-04	223
GO:0002709	GO:0002709	regulation of T cell mediated immunity	26/1988	50/8380	2.19	1.33e-05	2.01e-04	50
GO:0001773	GO:0001773	myeloid dendritic cell activation	14/1988	20/8380	2.95	1.51e-05	2.27e-04	20
GO:0070613	GO:0070613	regulation of protein processing	35/1988	76/8380	1.94	1.54e-05	2.31e-04	76
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	39/1988	88/8380	1.87	1.58e-05	2.35e-04	88
GO:0002719	GO:0002719	negative regulation of cytokine production involved in immune response	13/1988	18/8380	3.04	1.83e-05	2.71e-04	18
GO:0002685	GO:0002685	regulation of leukocyte migration	55/1988	139/8380	1.67	2.03e-05	3.00e-04	139
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	12/1988	16/8380	3.16	2.11e-05	3.10e-04	16
GO:0032653	GO:0032653	regulation of interleukin-10 production	20/1988	35/8380	2.41	2.18e-05	3.18e-04	35
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	35/1988	77/8380	1.92	2.19e-05	3.19e-04	77
GO:0030316	GO:0030316	osteoclast differentiation	29/1988	60/8380	2.04	2.66e-05	3.84e-04	60
GO:0032663	GO:0032663	regulation of interleukin-2 production	21/1988	38/8380	2.33	2.72e-05	3.89e-04	38
GO:0042093	GO:0042093	T-helper cell differentiation	21/1988	38/8380	2.33	2.72e-05	3.89e-04	38
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	15/1988	23/8380	2.75	2.73e-05	3.89e-04	23
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	15/1988	23/8380	2.75	2.73e-05	3.89e-04	23
GO:0071621	GO:0071621	granulocyte chemotaxis	42/1988	99/8380	1.79	2.77e-05	3.93e-04	99
GO:0099024	GO:0099024	plasma membrane invagination	19/1988	33/8380	2.43	3.03e-05	4.28e-04	33
GO:0050766	GO:0050766	positive regulation of phagocytosis	22/1988	41/8380	2.26	3.25e-05	4.58e-04	41
GO:0097530	GO:0097530	granulocyte migration	45/1988	109/8380	1.74	3.31e-05	4.64e-04	109
GO:0032479	GO:0032479	regulation of type I interferon production	23/1988	44/8380	2.20	3.75e-05	5.19e-04	44
GO:0032606	GO:0032606	type I interferon production	23/1988	44/8380	2.20	3.75e-05	5.19e-04	44
GO:0032613	GO:0032613	interleukin-10 production	20/1988	36/8380	2.34	3.81e-05	5.26e-04	36
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	29/1988	61/8380	2.00	3.93e-05	5.41e-04	61
GO:0050920	GO:0050920	regulation of chemotaxis	59/1988	155/8380	1.60	4.01e-05	5.49e-04	155
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	18/1988	31/8380	2.45	4.20e-05	5.70e-04	31
GO:0002369	GO:0002369	T cell cytokine production	16/1988	26/8380	2.59	4.20e-05	5.70e-04	26
GO:0042092	GO:0042092	type 2 immune response	16/1988	26/8380	2.59	4.20e-05	5.70e-04	26
GO:0002755	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/1988	19/8380	2.88	4.52e-05	6.05e-04	19
GO:0032480	GO:0032480	negative regulation of type I interferon production	13/1988	19/8380	2.88	4.52e-05	6.05e-04	19
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	13/1988	19/8380	2.88	4.52e-05	6.05e-04	19
GO:0010324	GO:0010324	membrane invagination	19/1988	34/8380	2.36	5.34e-05	7.12e-04	34
GO:0002407	GO:0002407	dendritic cell chemotaxis	12/1988	17/8380	2.98	5.63e-05	7.42e-04	17
GO:0002828	GO:0002828	regulation of type 2 immune response	15/1988	24/8380	2.63	5.68e-05	7.42e-04	24
GO:0010742	GO:0010742	macrophage derived foam cell differentiation	15/1988	24/8380	2.63	5.68e-05	7.42e-04	24
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	15/1988	24/8380	2.63	5.68e-05	7.42e-04	24
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	15/1988	24/8380	2.63	5.68e-05	7.42e-04	24
GO:0090077	GO:0090077	foam cell differentiation	15/1988	24/8380	2.63	5.68e-05	7.42e-04	24
GO:0030101	GO:0030101	natural killer cell activation	23/1988	45/8380	2.15	5.96e-05	7.72e-04	45
GO:0045576	GO:0045576	mast cell activation	23/1988	45/8380	2.15	5.96e-05	7.72e-04	45
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	34/1988	77/8380	1.86	5.97e-05	7.72e-04	77
GO:0002673	GO:0002673	regulation of acute inflammatory response	33/1988	74/8380	1.88	6.00e-05	7.73e-04	74
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	20/1988	37/8380	2.28	6.45e-05	8.26e-04	37
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	20/1988	37/8380	2.28	6.45e-05	8.26e-04	37
GO:0032607	GO:0032607	interferon-alpha production	11/1988	15/8380	3.09	6.76e-05	8.61e-04	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	11/1988	15/8380	3.09	6.76e-05	8.61e-04	15
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	14/1988	22/8380	2.68	7.62e-05	9.60e-04	22
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	14/1988	22/8380	2.68	7.62e-05	9.60e-04	22
GO:0002710	GO:0002710	negative regulation of T cell mediated immunity	10/1988	13/8380	3.24	7.70e-05	9.67e-04	13
GO:0002456	GO:0002456	T cell mediated immunity	33/1988	75/8380	1.85	8.30e-05	1.04e-03	75
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	32/1988	72/8380	1.87	8.37e-05	1.04e-03	72
GO:0048872	GO:0048872	homeostasis of number of cells	54/1988	142/8380	1.60	8.64e-05	1.07e-03	142
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	19/1988	35/8380	2.29	9.10e-05	1.13e-03	35
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	13/1988	20/8380	2.74	1.01e-04	1.24e-03	20
GO:0072606	GO:0072606	interleukin-8 secretion	13/1988	20/8380	2.74	1.01e-04	1.24e-03	20
GO:0072676	GO:0072676	lymphocyte migration	36/1988	85/8380	1.79	1.06e-04	1.30e-03	85
GO:0002548	GO:0002548	monocyte chemotaxis	26/1988	55/8380	1.99	1.10e-04	1.34e-03	55
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	15/1988	25/8380	2.53	1.11e-04	1.35e-03	25
GO:0042310	GO:0042310	vasoconstriction	27/1988	58/8380	1.96	1.13e-04	1.37e-03	58
GO:0046849	GO:0046849	bone remodeling	28/1988	61/8380	1.93	1.16e-04	1.39e-03	61
GO:0038093	GO:0038093	Fc receptor signaling pathway	29/1988	64/8380	1.91	1.17e-04	1.40e-03	64
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	30/1988	67/8380	1.89	1.17e-04	1.40e-03	67
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	12/1988	18/8380	2.81	1.32e-04	1.57e-03	18
GO:0030593	GO:0030593	neutrophil chemotaxis	36/1988	86/8380	1.76	1.41e-04	1.66e-03	86
GO:1990868	GO:1990868	response to chemokine	35/1988	83/8380	1.78	1.46e-04	1.71e-03	83
GO:1990869	GO:1990869	cellular response to chemokine	35/1988	83/8380	1.78	1.46e-04	1.71e-03	83
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	16/1988	28/8380	2.41	1.47e-04	1.71e-03	28
GO:0002820	GO:0002820	negative regulation of adaptive immune response	16/1988	28/8380	2.41	1.47e-04	1.71e-03	28
GO:0043277	GO:0043277	apoptotic cell clearance	16/1988	28/8380	2.41	1.47e-04	1.71e-03	28
GO:0032620	GO:0032620	interleukin-17 production	14/1988	23/8380	2.57	1.52e-04	1.77e-03	23
GO:0050921	GO:0050921	positive regulation of chemotaxis	39/1988	96/8380	1.71	1.63e-04	1.89e-03	96
GO:0051604	GO:0051604	protein maturation	62/1988	172/8380	1.52	1.64e-04	1.89e-03	172
GO:0032720	GO:0032720	negative regulation of tumor necrosis factor production	20/1988	39/8380	2.16	1.70e-04	1.93e-03	39
GO:0002043	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	11/1988	16/8380	2.90	1.70e-04	1.93e-03	16
GO:0002577	GO:0002577	regulation of antigen processing and presentation	11/1988	16/8380	2.90	1.70e-04	1.93e-03	16
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	11/1988	16/8380	2.90	1.70e-04	1.93e-03	16
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	11/1988	16/8380	2.90	1.70e-04	1.93e-03	16
GO:1990266	GO:1990266	neutrophil migration	38/1988	93/8380	1.72	1.71e-04	1.93e-03	93
GO:0016485	GO:0016485	protein processing	56/1988	152/8380	1.55	1.74e-04	1.96e-03	152
GO:0002526	GO:0002526	acute inflammatory response	45/1988	116/8380	1.64	1.92e-04	2.16e-03	116
GO:0007162	GO:0007162	negative regulation of cell adhesion	62/1988	173/8380	1.51	1.98e-04	2.21e-03	173
GO:0002228	GO:0002228	natural killer cell mediated immunity	22/1988	45/8380	2.06	2.00e-04	2.23e-03	45
GO:0019229	GO:0019229	regulation of vasoconstriction	22/1988	45/8380	2.06	2.00e-04	2.23e-03	45
GO:0002474	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	15/1988	26/8380	2.43	2.05e-04	2.26e-03	26
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	15/1988	26/8380	2.43	2.05e-04	2.26e-03	26
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	13/1988	21/8380	2.61	2.08e-04	2.28e-03	21
GO:0045066	GO:0045066	regulatory T cell differentiation	13/1988	21/8380	2.61	2.08e-04	2.28e-03	21
GO:0071825	GO:0071825	protein-lipid complex subunit organization	18/1988	34/8380	2.23	2.13e-04	2.33e-03	34
GO:0001906	GO:0001906	cell killing	43/1988	110/8380	1.65	2.17e-04	2.36e-03	110
GO:0000187	GO:0000187	activation of MAPK activity	38/1988	94/8380	1.70	2.23e-04	2.42e-03	94
GO:0042116	GO:0042116	macrophage activation	26/1988	57/8380	1.92	2.28e-04	2.46e-03	57
GO:0032612	GO:0032612	interleukin-1 production	28/1988	63/8380	1.87	2.29e-04	2.46e-03	63
GO:0001776	GO:0001776	leukocyte homeostasis	27/1988	60/8380	1.90	2.29e-04	2.46e-03	60
GO:0097756	GO:0097756	negative regulation of blood vessel diameter	27/1988	60/8380	1.90	2.29e-04	2.46e-03	60
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	9/1988	12/8380	3.16	2.52e-04	2.68e-03	12
GO:0034162	GO:0034162	toll-like receptor 9 signaling pathway	9/1988	12/8380	3.16	2.52e-04	2.68e-03	12
GO:2000484	GO:2000484	positive regulation of interleukin-8 secretion	9/1988	12/8380	3.16	2.52e-04	2.68e-03	12
GO:0002712	GO:0002712	regulation of B cell mediated immunity	16/1988	29/8380	2.33	2.55e-04	2.68e-03	29
GO:0002889	GO:0002889	regulation of immunoglobulin mediated immune response	16/1988	29/8380	2.33	2.55e-04	2.68e-03	29
GO:0033003	GO:0033003	regulation of mast cell activation	16/1988	29/8380	2.33	2.55e-04	2.68e-03	29
GO:0043300	GO:0043300	regulation of leukocyte degranulation	16/1988	29/8380	2.33	2.55e-04	2.68e-03	29
GO:0045670	GO:0045670	regulation of osteoclast differentiation	20/1988	40/8380	2.11	2.64e-04	2.75e-03	40
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	20/1988	40/8380	2.11	2.64e-04	2.75e-03	40
GO:0002517	GO:0002517	T cell tolerance induction	8/1988	10/8380	3.37	2.79e-04	2.88e-03	10
GO:0033004	GO:0033004	negative regulation of mast cell activation	8/1988	10/8380	3.37	2.79e-04	2.88e-03	10
GO:0036336	GO:0036336	dendritic cell migration	12/1988	19/8380	2.66	2.82e-04	2.91e-03	19
GO:1902622	GO:1902622	regulation of neutrophil migration	14/1988	24/8380	2.46	2.86e-04	2.94e-03	24
GO:0046718	GO:0046718	viral entry into host cell	32/1988	76/8380	1.77	2.86e-04	2.94e-03	76
GO:0070227	GO:0070227	lymphocyte apoptotic process	22/1988	46/8380	2.02	2.98e-04	3.05e-03	46
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	17/1988	32/8380	2.24	3.01e-04	3.08e-03	32
GO:0031348	GO:0031348	negative regulation of defense response	45/1988	118/8380	1.61	3.03e-04	3.08e-03	118
GO:0032755	GO:0032755	positive regulation of interleukin-6 production	24/1988	52/8380	1.95	3.16e-04	3.21e-03	52
GO:0002920	GO:0002920	regulation of humoral immune response	25/1988	55/8380	1.92	3.20e-04	3.24e-03	55
GO:0045862	GO:0045862	positive regulation of proteolysis	58/1988	162/8380	1.51	3.23e-04	3.26e-03	162
GO:0031345	GO:0031345	negative regulation of cell projection organization	44/1988	115/8380	1.61	3.23e-04	3.26e-03	115
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	18/1988	35/8380	2.17	3.41e-04	3.43e-03	35
GO:0046330	GO:0046330	positive regulation of JNK cascade	38/1988	96/8380	1.67	3.69e-04	3.69e-03	96
GO:0035743	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	11/1988	17/8380	2.73	3.78e-04	3.76e-03	17
GO:2000482	GO:2000482	regulation of interleukin-8 secretion	11/1988	17/8380	2.73	3.78e-04	3.76e-03	17
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	13/1988	22/8380	2.49	3.98e-04	3.92e-03	22
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	13/1988	22/8380	2.49	3.98e-04	3.92e-03	22
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	20/1988	41/8380	2.06	4.02e-04	3.95e-03	41
GO:0032368	GO:0032368	regulation of lipid transport	30/1988	71/8380	1.78	4.08e-04	4.00e-03	71
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	29/1988	68/8380	1.80	4.20e-04	4.11e-03	68
GO:0072678	GO:0072678	T cell migration	22/1988	47/8380	1.97	4.36e-04	4.26e-03	47
GO:0019722	GO:0019722	calcium-mediated signaling	54/1988	150/8380	1.52	4.38e-04	4.26e-03	150
GO:0030183	GO:0030183	B cell differentiation	27/1988	62/8380	1.84	4.40e-04	4.27e-03	62
GO:0097006	GO:0097006	regulation of plasma lipoprotein particle levels	24/1988	53/8380	1.91	4.49e-04	4.35e-03	53
GO:0030260	GO:0030260	entry into host cell	33/1988	81/8380	1.72	4.77e-04	4.57e-03	81
GO:0044409	GO:0044409	entry into host	33/1988	81/8380	1.72	4.77e-04	4.57e-03	81
GO:0051806	GO:0051806	entry into cell of other organism involved in symbiotic interaction	33/1988	81/8380	1.72	4.77e-04	4.57e-03	81
GO:0051828	GO:0051828	entry into other organism involved in symbiotic interaction	33/1988	81/8380	1.72	4.77e-04	4.57e-03	81
GO:0042533	GO:0042533	tumor necrosis factor biosynthetic process	10/1988	15/8380	2.81	5.00e-04	4.73e-03	15
GO:0042534	GO:0042534	regulation of tumor necrosis factor biosynthetic process	10/1988	15/8380	2.81	5.00e-04	4.73e-03	15
GO:0055094	GO:0055094	response to lipoprotein particle	10/1988	15/8380	2.81	5.00e-04	4.73e-03	15
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	10/1988	15/8380	2.81	5.00e-04	4.73e-03	15
GO:0006958	GO:0006958	complement activation, classical pathway	14/1988	25/8380	2.36	5.09e-04	4.77e-03	25
GO:0032673	GO:0032673	regulation of interleukin-4 production	14/1988	25/8380	2.36	5.09e-04	4.77e-03	25
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	14/1988	25/8380	2.36	5.09e-04	4.77e-03	25
GO:0002724	GO:0002724	regulation of T cell cytokine production	12/1988	20/8380	2.53	5.53e-04	5.12e-03	20
GO:0032660	GO:0032660	regulation of interleukin-17 production	12/1988	20/8380	2.53	5.53e-04	5.12e-03	20
GO:0071353	GO:0071353	cellular response to interleukin-4	12/1988	20/8380	2.53	5.53e-04	5.12e-03	20
GO:1902624	GO:1902624	positive regulation of neutrophil migration	12/1988	20/8380	2.53	5.53e-04	5.12e-03	20
GO:0030449	GO:0030449	regulation of complement activation	19/1988	39/8380	2.05	5.70e-04	5.26e-03	39
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	20/1988	42/8380	2.01	5.97e-04	5.50e-03	42
GO:0002437	GO:0002437	inflammatory response to antigenic stimulus	15/1988	28/8380	2.26	6.07e-04	5.58e-03	28
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	33/1988	82/8380	1.70	6.20e-04	5.67e-03	82
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	33/1988	82/8380	1.70	6.20e-04	5.67e-03	82
GO:1905954	GO:1905954	positive regulation of lipid localization	25/1988	57/8380	1.85	6.23e-04	5.68e-03	57
GO:0010878	GO:0010878	cholesterol storage	9/1988	13/8380	2.92	6.47e-04	5.85e-03	13
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	9/1988	13/8380	2.92	6.47e-04	5.85e-03	13
GO:0045072	GO:0045072	regulation of interferon-gamma biosynthetic process	9/1988	13/8380	2.92	6.47e-04	5.85e-03	13
GO:0050690	GO:0050690	regulation of defense response to virus by virus	9/1988	13/8380	2.92	6.47e-04	5.85e-03	13
GO:0002687	GO:0002687	positive regulation of leukocyte migration	36/1988	92/8380	1.65	6.72e-04	6.04e-03	92
GO:1905952	GO:1905952	regulation of lipid localization	36/1988	92/8380	1.65	6.72e-04	6.04e-03	92
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	48/1988	132/8380	1.53	6.89e-04	6.17e-03	132
GO:0071827	GO:0071827	plasma lipoprotein particle organization	16/1988	31/8380	2.18	6.91e-04	6.17e-03	31
GO:0070304	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	42/1988	112/8380	1.58	7.11e-04	6.34e-03	112
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	13/1988	23/8380	2.38	7.18e-04	6.39e-03	23
GO:0055076	GO:0055076	transition metal ion homeostasis	29/1988	70/8380	1.75	7.46e-04	6.62e-03	70
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	11/1988	18/8380	2.58	7.65e-04	6.74e-03	18
GO:1901623	GO:1901623	regulation of lymphocyte chemotaxis	11/1988	18/8380	2.58	7.65e-04	6.74e-03	18
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	33/1988	83/8380	1.68	7.98e-04	7.01e-03	83
GO:0010885	GO:0010885	regulation of cholesterol storage	8/1988	11/8380	3.07	8.09e-04	7.03e-03	11
GO:0032727	GO:0032727	positive regulation of interferon-alpha production	8/1988	11/8380	3.07	8.09e-04	7.03e-03	11
GO:0043011	GO:0043011	myeloid dendritic cell differentiation	8/1988	11/8380	3.07	8.09e-04	7.03e-03	11
GO:0043373	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	8/1988	11/8380	3.07	8.09e-04	7.03e-03	11
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	18/1988	37/8380	2.05	8.10e-04	7.03e-03	37
GO:0060402	GO:0060402	calcium ion transport into cytosol	40/1988	106/8380	1.59	8.16e-04	7.07e-03	106
GO:0045453	GO:0045453	bone resorption	19/1988	40/8380	2.00	8.47e-04	7.27e-03	40
GO:0050701	GO:0050701	interleukin-1 secretion	19/1988	40/8380	2.00	8.47e-04	7.27e-03	40
GO:2000257	GO:2000257	regulation of protein activation cascade	19/1988	40/8380	2.00	8.47e-04	7.27e-03	40
GO:0032637	GO:0032637	interleukin-8 production	20/1988	43/8380	1.96	8.71e-04	7.44e-03	43
GO:0030168	GO:0030168	platelet activation	39/1988	103/8380	1.60	8.74e-04	7.45e-03	103
GO:0048247	GO:0048247	lymphocyte chemotaxis	23/1988	52/8380	1.86	8.81e-04	7.47e-03	52
GO:0033077	GO:0033077	T cell differentiation in thymus	21/1988	46/8380	1.92	8.83e-04	7.47e-03	46
GO:0045123	GO:0045123	cellular extravasation	21/1988	46/8380	1.92	8.83e-04	7.47e-03	46
GO:0050871	GO:0050871	positive regulation of B cell activation	21/1988	46/8380	1.92	8.83e-04	7.47e-03	46
GO:0060401	GO:0060401	cytosolic calcium ion transport	40/1988	107/8380	1.58	1.01e-03	8.49e-03	107
GO:0010743	GO:0010743	regulation of macrophage derived foam cell differentiation	12/1988	21/8380	2.41	1.01e-03	8.49e-03	21
GO:0051208	GO:0051208	sequestering of calcium ion	33/1988	84/8380	1.66	1.02e-03	8.53e-03	84
GO:0002360	GO:0002360	T cell lineage commitment	10/1988	16/8380	2.63	1.05e-03	8.68e-03	16
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	10/1988	16/8380	2.63	1.05e-03	8.68e-03	16
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	10/1988	16/8380	2.63	1.05e-03	8.68e-03	16
GO:0071402	GO:0071402	cellular response to lipoprotein particle stimulus	10/1988	16/8380	2.63	1.05e-03	8.68e-03	16
GO:0072538	GO:0072538	T-helper 17 type immune response	10/1988	16/8380	2.63	1.05e-03	8.68e-03	16
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	26/1988	62/8380	1.77	1.11e-03	9.15e-03	62
GO:0050702	GO:0050702	interleukin-1 beta secretion	17/1988	35/8380	2.05	1.15e-03	9.47e-03	35
GO:0032874	GO:0032874	positive regulation of stress-activated MAPK cascade	41/1988	111/8380	1.56	1.16e-03	9.49e-03	111
GO:0046916	GO:0046916	cellular transition metal ion homeostasis	24/1988	56/8380	1.81	1.18e-03	9.69e-03	56
GO:0002312	GO:0002312	B cell activation involved in immune response	18/1988	38/8380	2.00	1.20e-03	9.80e-03	38
GO:0042130	GO:0042130	negative regulation of T cell proliferation	18/1988	38/8380	2.00	1.20e-03	9.80e-03	38
GO:0032370	GO:0032370	positive regulation of lipid transport	19/1988	41/8380	1.95	1.23e-03	1.00e-02	41
GO:0070228	GO:0070228	regulation of lymphocyte apoptotic process	19/1988	41/8380	1.95	1.23e-03	1.00e-02	41
GO:0043281	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	40/1988	108/8380	1.56	1.24e-03	1.01e-02	108
GO:0050710	GO:0050710	negative regulation of cytokine secretion	20/1988	44/8380	1.92	1.24e-03	1.01e-02	44
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	37/1988	98/8380	1.59	1.25e-03	1.01e-02	98
GO:0046488	GO:0046488	phosphatidylinositol metabolic process	44/1988	122/8380	1.52	1.37e-03	1.10e-02	122
GO:0001774	GO:0001774	microglial cell activation	14/1988	27/8380	2.19	1.40e-03	1.12e-02	27
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	14/1988	27/8380	2.19	1.40e-03	1.12e-02	27
GO:0046633	GO:0046633	alpha-beta T cell proliferation	14/1988	27/8380	2.19	1.40e-03	1.12e-02	27
GO:0015908	GO:0015908	fatty acid transport	27/1988	66/8380	1.72	1.41e-03	1.12e-02	66
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	11/1988	19/8380	2.44	1.43e-03	1.13e-02	19
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	11/1988	19/8380	2.44	1.43e-03	1.13e-02	19
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	9/1988	14/8380	2.71	1.43e-03	1.13e-02	14
GO:0002643	GO:0002643	regulation of tolerance induction	9/1988	14/8380	2.71	1.43e-03	1.13e-02	14
GO:0042095	GO:0042095	interferon-gamma biosynthetic process	9/1988	14/8380	2.71	1.43e-03	1.13e-02	14
GO:0045063	GO:0045063	T-helper 1 cell differentiation	9/1988	14/8380	2.71	1.43e-03	1.13e-02	14
GO:0140131	GO:0140131	positive regulation of lymphocyte chemotaxis	9/1988	14/8380	2.71	1.43e-03	1.13e-02	14
GO:0032633	GO:0032633	interleukin-4 production	15/1988	30/8380	2.11	1.54e-03	1.20e-02	30
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	15/1988	30/8380	2.11	1.54e-03	1.20e-02	30
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	16/1988	33/8380	2.04	1.64e-03	1.27e-02	33
GO:0006956	GO:0006956	complement activation	23/1988	54/8380	1.80	1.64e-03	1.27e-02	54
GO:0032611	GO:0032611	interleukin-1 beta production	23/1988	54/8380	1.80	1.64e-03	1.27e-02	54
GO:0032652	GO:0032652	regulation of interleukin-1 production	23/1988	54/8380	1.80	1.64e-03	1.27e-02	54
GO:0014068	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	22/1988	51/8380	1.82	1.69e-03	1.30e-02	51
GO:0002686	GO:0002686	negative regulation of leukocyte migration	17/1988	36/8380	1.99	1.71e-03	1.31e-02	36
GO:0050922	GO:0050922	negative regulation of chemotaxis	21/1988	48/8380	1.84	1.72e-03	1.32e-02	48
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0034367	GO:0034367	protein-containing complex remodeling	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0034368	GO:0034368	protein-lipid complex remodeling	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0034369	GO:0034369	plasma lipoprotein particle remodeling	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0045907	GO:0045907	positive regulation of vasoconstriction	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0070670	GO:0070670	response to interleukin-4	12/1988	22/8380	2.30	1.75e-03	1.33e-02	22
GO:0001913	GO:0001913	T cell mediated cytotoxicity	19/1988	42/8380	1.91	1.75e-03	1.33e-02	42
GO:2000401	GO:2000401	regulation of lymphocyte migration	19/1988	42/8380	1.91	1.75e-03	1.33e-02	42
GO:0051701	GO:0051701	interaction with host	38/1988	103/8380	1.56	1.77e-03	1.33e-02	103
GO:0010977	GO:0010977	negative regulation of neuron projection development	37/1988	100/8380	1.56	1.90e-03	1.43e-02	100
GO:0010744	GO:0010744	positive regulation of macrophage derived foam cell differentiation	8/1988	12/8380	2.81	1.92e-03	1.44e-02	12
GO:0002381	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	13/1988	25/8380	2.19	2.01e-03	1.50e-02	25
GO:1903672	GO:1903672	positive regulation of sprouting angiogenesis	13/1988	25/8380	2.19	2.01e-03	1.50e-02	25
GO:0002832	GO:0002832	negative regulation of response to biotic stimulus	10/1988	17/8380	2.48	2.01e-03	1.50e-02	17
GO:2000108	GO:2000108	positive regulation of leukocyte apoptotic process	10/1988	17/8380	2.48	2.01e-03	1.50e-02	17
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	33/1988	87/8380	1.60	2.04e-03	1.51e-02	87
GO:0035296	GO:0035296	regulation of tube diameter	36/1988	97/8380	1.56	2.04e-03	1.51e-02	97
GO:0097746	GO:0097746	regulation of blood vessel diameter	36/1988	97/8380	1.56	2.04e-03	1.51e-02	97
GO:0001935	GO:0001935	endothelial cell proliferation	35/1988	94/8380	1.57	2.20e-03	1.62e-02	94
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	23/1988	55/8380	1.76	2.20e-03	1.62e-02	55
GO:0002200	GO:0002200	somatic diversification of immune receptors	14/1988	28/8380	2.11	2.20e-03	1.62e-02	28
GO:0038083	GO:0038083	peptidyl-tyrosine autophosphorylation	14/1988	28/8380	2.11	2.20e-03	1.62e-02	28
GO:0051482	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	14/1988	28/8380	2.11	2.20e-03	1.62e-02	28
GO:0002279	GO:0002279	mast cell activation involved in immune response	16/1988	34/8380	1.98	2.42e-03	1.77e-02	34
GO:0010818	GO:0010818	T cell chemotaxis	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0032608	GO:0032608	interferon-beta production	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0032648	GO:0032648	regulation of interferon-beta production	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0043032	GO:0043032	positive regulation of macrophage activation	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0065005	GO:0065005	protein-lipid complex assembly	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	11/1988	20/8380	2.32	2.50e-03	1.77e-02	20
GO:0070555	GO:0070555	response to interleukin-1	36/1988	98/8380	1.55	2.51e-03	1.77e-02	98
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	41/1988	115/8380	1.50	2.51e-03	1.77e-02	115
GO:0002295	GO:0002295	T-helper cell lineage commitment	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0002430	GO:0002430	complement receptor mediated signaling pathway	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0010819	GO:0010819	regulation of T cell chemotaxis	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0031223	GO:0031223	auditory behavior	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0032490	GO:0032490	detection of molecule of bacterial origin	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0035666	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0035747	GO:0035747	natural killer cell chemotaxis	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0036005	GO:0036005	response to macrophage colony-stimulating factor	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0036006	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0042535	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0045591	GO:0045591	positive regulation of regulatory T cell differentiation	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:0070230	GO:0070230	positive regulation of lymphocyte apoptotic process	7/1988	10/8380	2.95	2.52e-03	1.77e-02	10
GO:1903034	GO:1903034	regulation of response to wounding	38/1988	105/8380	1.53	2.62e-03	1.84e-02	105
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	25/1988	62/8380	1.70	2.64e-03	1.85e-02	62
GO:1904892	GO:1904892	regulation of STAT cascade	29/1988	75/8380	1.63	2.66e-03	1.86e-02	75
GO:0001779	GO:0001779	natural killer cell differentiation	9/1988	15/8380	2.53	2.83e-03	1.95e-02	15
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	9/1988	15/8380	2.53	2.83e-03	1.95e-02	15
GO:0051354	GO:0051354	negative regulation of oxidoreductase activity	9/1988	15/8380	2.53	2.83e-03	1.95e-02	15
GO:0072539	GO:0072539	T-helper 17 cell differentiation	9/1988	15/8380	2.53	2.83e-03	1.95e-02	15
GO:0046425	GO:0046425	regulation of JAK-STAT cascade	28/1988	72/8380	1.64	2.84e-03	1.96e-02	72
GO:0001937	GO:0001937	negative regulation of endothelial cell proliferation	12/1988	23/8380	2.20	2.88e-03	1.98e-02	23
GO:0016445	GO:0016445	somatic diversification of immunoglobulins	12/1988	23/8380	2.20	2.88e-03	1.98e-02	23
GO:0032642	GO:0032642	regulation of chemokine production	23/1988	56/8380	1.73	2.91e-03	2.00e-02	56
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	27/1988	69/8380	1.65	3.02e-03	2.06e-02	69
GO:1903725	GO:1903725	regulation of phospholipid metabolic process	22/1988	53/8380	1.75	3.04e-03	2.07e-02	53
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	13/1988	26/8380	2.11	3.15e-03	2.12e-02	26
GO:0010955	GO:0010955	negative regulation of protein processing	13/1988	26/8380	2.11	3.15e-03	2.12e-02	26
GO:0032481	GO:0032481	positive regulation of type I interferon production	13/1988	26/8380	2.11	3.15e-03	2.12e-02	26
GO:0050850	GO:0050850	positive regulation of calcium-mediated signaling	13/1988	26/8380	2.11	3.15e-03	2.12e-02	26
GO:1903318	GO:1903318	negative regulation of protein maturation	13/1988	26/8380	2.11	3.15e-03	2.12e-02	26
GO:0010517	GO:0010517	regulation of phospholipase activity	21/1988	50/8380	1.77	3.17e-03	2.13e-02	50
GO:0002260	GO:0002260	lymphocyte homeostasis	19/1988	44/8380	1.82	3.37e-03	2.26e-02	44
GO:0060191	GO:0060191	regulation of lipase activity	25/1988	63/8380	1.67	3.40e-03	2.28e-02	63
GO:0002637	GO:0002637	regulation of immunoglobulin production	15/1988	32/8380	1.98	3.45e-03	2.30e-02	32
GO:0034381	GO:0034381	plasma lipoprotein particle clearance	15/1988	32/8380	1.98	3.45e-03	2.30e-02	32
GO:1903036	GO:1903036	positive regulation of response to wounding	17/1988	38/8380	1.89	3.49e-03	2.31e-02	38
GO:0032418	GO:0032418	lysosome localization	16/1988	35/8380	1.93	3.49e-03	2.31e-02	35
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	16/1988	35/8380	1.93	3.49e-03	2.31e-02	35
GO:0090303	GO:0090303	positive regulation of wound healing	16/1988	35/8380	1.93	3.49e-03	2.31e-02	35
GO:0061041	GO:0061041	regulation of wound healing	34/1988	93/8380	1.54	3.56e-03	2.35e-02	93
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	10/1988	18/8380	2.34	3.57e-03	2.36e-02	18
GO:0032602	GO:0032602	chemokine production	24/1988	60/8380	1.69	3.60e-03	2.37e-02	60
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	31/1988	83/8380	1.57	3.62e-03	2.38e-02	83
GO:0072376	GO:0072376	protein activation cascade	27/1988	70/8380	1.63	3.82e-03	2.51e-02	70
GO:0002756	GO:0002756	MyD88-independent toll-like receptor signaling pathway	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0006925	GO:0006925	inflammatory cell apoptotic process	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0032728	GO:0032728	positive regulation of interferon-beta production	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0060330	GO:0060330	regulation of response to interferon-gamma	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0060334	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0060396	GO:0060396	growth hormone receptor signaling pathway	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0071378	GO:0071378	cellular response to growth hormone stimulus	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:2000353	GO:2000353	positive regulation of endothelial cell apoptotic process	8/1988	13/8380	2.59	3.96e-03	2.56e-02	13
GO:0002753	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	11/1988	21/8380	2.21	4.13e-03	2.66e-02	21
GO:0033006	GO:0033006	regulation of mast cell activation involved in immune response	11/1988	21/8380	2.21	4.13e-03	2.66e-02	21
GO:0035150	GO:0035150	regulation of tube size	36/1988	101/8380	1.50	4.47e-03	2.86e-02	101
GO:0050880	GO:0050880	regulation of blood vessel size	36/1988	101/8380	1.50	4.47e-03	2.86e-02	101
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	12/1988	24/8380	2.11	4.53e-03	2.88e-02	24
GO:1904645	GO:1904645	response to amyloid-beta	12/1988	24/8380	2.11	4.53e-03	2.88e-02	24
GO:0032722	GO:0032722	positive regulation of chemokine production	18/1988	42/8380	1.81	4.72e-03	3.00e-02	42
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	18/1988	42/8380	1.81	4.72e-03	3.00e-02	42
GO:0032689	GO:0032689	negative regulation of interferon-gamma production	13/1988	27/8380	2.03	4.78e-03	3.02e-02	27
GO:0090279	GO:0090279	regulation of calcium ion import	13/1988	27/8380	2.03	4.78e-03	3.02e-02	27
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	13/1988	27/8380	2.03	4.78e-03	3.02e-02	27
GO:0002431	GO:0002431	Fc receptor mediated stimulatory signaling pathway	17/1988	39/8380	1.84	4.84e-03	3.04e-02	39
GO:0002532	GO:0002532	production of molecular mediator involved in inflammatory response	17/1988	39/8380	1.84	4.84e-03	3.04e-02	39
GO:0032677	GO:0032677	regulation of interleukin-8 production	17/1988	39/8380	1.84	4.84e-03	3.04e-02	39
GO:0032757	GO:0032757	positive regulation of interleukin-8 production	14/1988	30/8380	1.97	4.91e-03	3.07e-02	30
GO:0033344	GO:0033344	cholesterol efflux	14/1988	30/8380	1.97	4.91e-03	3.07e-02	30
GO:0060443	GO:0060443	mammary gland morphogenesis	16/1988	36/8380	1.87	4.93e-03	3.07e-02	36
GO:0043303	GO:0043303	mast cell degranulation	15/1988	33/8380	1.92	4.95e-03	3.07e-02	33
GO:0061900	GO:0061900	glial cell activation	15/1988	33/8380	1.92	4.95e-03	3.07e-02	33
GO:0070231	GO:0070231	T cell apoptotic process	15/1988	33/8380	1.92	4.95e-03	3.07e-02	33
GO:0002689	GO:0002689	negative regulation of leukocyte chemotaxis	9/1988	16/8380	2.37	5.11e-03	3.15e-02	16
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	9/1988	16/8380	2.37	5.11e-03	3.15e-02	16
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	26/1988	68/8380	1.61	5.15e-03	3.16e-02	68
GO:0030301	GO:0030301	cholesterol transport	22/1988	55/8380	1.69	5.20e-03	3.19e-02	55
GO:0050818	GO:0050818	regulation of coagulation	25/1988	65/8380	1.62	5.51e-03	3.31e-02	65
GO:0007638	GO:0007638	mechanosensory behavior	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0010715	GO:0010715	regulation of extracellular matrix disassembly	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0034433	GO:0034433	steroid esterification	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0034434	GO:0034434	sterol esterification	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0034435	GO:0034435	cholesterol esterification	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0042447	GO:0042447	hormone catabolic process	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0043371	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0060252	GO:0060252	positive regulation of glial cell proliferation	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0071404	GO:0071404	cellular response to low-density lipoprotein particle stimulus	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0120033	GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	7/1988	11/8380	2.68	5.51e-03	3.31e-02	11
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	28/1988	75/8380	1.57	5.56e-03	3.34e-02	75
GO:0061025	GO:0061025	membrane fusion	24/1988	62/8380	1.63	5.88e-03	3.51e-02	62
GO:0002204	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0002208	GO:0002208	somatic diversification of immunoglobulins involved in immune response	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0045190	GO:0045190	isotype switching	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0045577	GO:0045577	regulation of B cell differentiation	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0048873	GO:0048873	homeostasis of number of cells within a tissue	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0050691	GO:0050691	regulation of defense response to virus by host	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0070207	GO:0070207	protein homotrimerization	10/1988	19/8380	2.22	5.95e-03	3.51e-02	19
GO:0034113	GO:0034113	heterotypic cell-cell adhesion	19/1988	46/8380	1.74	6.07e-03	3.56e-02	46
GO:0043154	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	19/1988	46/8380	1.74	6.07e-03	3.56e-02	46
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	18/1988	43/8380	1.76	6.35e-03	3.71e-02	43
GO:0034110	GO:0034110	regulation of homotypic cell-cell adhesion	11/1988	22/8380	2.11	6.51e-03	3.78e-02	22
GO:0044764	GO:0044764	multi-organism cellular process	11/1988	22/8380	2.11	6.51e-03	3.78e-02	22
GO:0050901	GO:0050901	leukocyte tethering or rolling	11/1988	22/8380	2.11	6.51e-03	3.78e-02	22
GO:0150076	GO:0150076	neuroinflammatory response	17/1988	40/8380	1.79	6.59e-03	3.81e-02	40
GO:2000058	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	17/1988	40/8380	1.79	6.59e-03	3.81e-02	40
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	12/1988	25/8380	2.02	6.85e-03	3.95e-02	25
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	15/1988	34/8380	1.86	6.95e-03	4.00e-02	34
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	13/1988	28/8380	1.96	7.01e-03	4.02e-02	28
GO:0032715	GO:0032715	negative regulation of interleukin-6 production	13/1988	28/8380	1.96	7.01e-03	4.02e-02	28
GO:0045124	GO:0045124	regulation of bone resorption	13/1988	28/8380	1.96	7.01e-03	4.02e-02	28
GO:0030890	GO:0030890	positive regulation of B cell proliferation	14/1988	31/8380	1.90	7.03e-03	4.02e-02	31
GO:0031100	GO:0031100	animal organ regeneration	21/1988	53/8380	1.67	7.11e-03	4.06e-02	53
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	8/1988	14/8380	2.41	7.33e-03	4.17e-02	14
GO:0031954	GO:0031954	positive regulation of protein autophosphorylation	8/1988	14/8380	2.41	7.33e-03	4.17e-02	14
GO:0097242	GO:0097242	amyloid-beta clearance	8/1988	14/8380	2.41	7.33e-03	4.17e-02	14
GO:0030193	GO:0030193	regulation of blood coagulation	24/1988	63/8380	1.61	7.41e-03	4.20e-02	63
GO:1900046	GO:1900046	regulation of hemostasis	24/1988	63/8380	1.61	7.41e-03	4.20e-02	63
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	20/1988	50/8380	1.69	7.54e-03	4.26e-02	50
GO:2000117	GO:2000117	negative regulation of cysteine-type endopeptidase activity	20/1988	50/8380	1.69	7.54e-03	4.26e-02	50
GO:0050709	GO:0050709	negative regulation of protein secretion	29/1988	80/8380	1.53	7.76e-03	4.38e-02	80
GO:0015909	GO:0015909	long-chain fatty acid transport	19/1988	47/8380	1.70	7.97e-03	4.49e-02	47
GO:0050728	GO:0050728	negative regulation of inflammatory response	31/1988	87/8380	1.50	8.02e-03	4.51e-02	87
GO:0006919	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	18/1988	44/8380	1.72	8.40e-03	4.68e-02	44
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0009595	GO:0009595	detection of biotic stimulus	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0031664	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0034377	GO:0034377	plasma lipoprotein particle assembly	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0042832	GO:0042832	defense response to protozoan	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0045671	GO:0045671	negative regulation of osteoclast differentiation	9/1988	17/8380	2.23	8.60e-03	4.74e-02	17
GO:0002220	GO:0002220	innate immune response activating cell surface receptor signaling pathway	17/1988	41/8380	1.75	8.82e-03	4.84e-02	41

Factor 17 : 257 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	148/1096	309/8380	3.66	1.91e-52	8.10e-49	309
GO:0000278	GO:0000278	mitotic cell cycle	161/1096	370/8380	3.33	4.80e-50	1.02e-46	370
GO:0051276	GO:0051276	chromosome organization	152/1096	406/8380	2.86	1.55e-37	2.20e-34	406
GO:0007059	GO:0007059	chromosome segregation	77/1096	126/8380	4.67	4.12e-37	4.05e-34	126
GO:0044772	GO:0044772	mitotic cell cycle phase transition	97/1096	191/8380	3.88	4.77e-37	4.05e-34	191
GO:0044770	GO:0044770	cell cycle phase transition	100/1096	206/8380	3.71	5.46e-36	3.87e-33	206
GO:0051301	GO:0051301	cell division	112/1096	255/8380	3.36	4.09e-35	2.49e-32	255
GO:0000819	GO:0000819	sister chromatid segregation	56/1096	76/8380	5.63	7.69e-34	4.09e-31	76
GO:0140014	GO:0140014	mitotic nuclear division	71/1096	122/8380	4.45	2.47e-32	1.17e-29	122
GO:0006260	GO:0006260	DNA replication	62/1096	96/8380	4.94	4.57e-32	1.94e-29	96
GO:0098813	GO:0098813	nuclear chromosome segregation	67/1096	112/8380	4.57	1.38e-31	5.32e-29	112
GO:0000070	GO:0000070	mitotic sister chromatid segregation	47/1096	60/8380	5.99	1.18e-30	4.17e-28	60
GO:0000280	GO:0000280	nuclear division	90/1096	198/8380	3.48	1.09e-29	3.57e-27	198
GO:0048285	GO:0048285	organelle fission	94/1096	215/8380	3.34	2.41e-29	7.31e-27	215
GO:0006259	GO:0006259	DNA metabolic process	120/1096	330/8380	2.78	3.28e-28	9.28e-26	330
GO:0006261	GO:0006261	DNA-dependent DNA replication	42/1096	55/8380	5.84	1.03e-26	2.73e-24	55
GO:0010564	GO:0010564	regulation of cell cycle process	102/1096	279/8380	2.80	2.97e-24	7.43e-22	279
GO:0051726	GO:0051726	regulation of cell cycle	140/1096	465/8380	2.30	2.14e-23	5.05e-21	465
GO:0051983	GO:0051983	regulation of chromosome segregation	33/1096	40/8380	6.31	3.41e-23	7.62e-21	40
GO:0006974	GO:0006974	cellular response to DNA damage stimulus	96/1096	268/8380	2.74	4.07e-22	8.64e-20	268
GO:0071103	GO:0071103	DNA conformation change	58/1096	120/8380	3.70	4.03e-21	8.16e-19	120
GO:0006281	GO:0006281	DNA repair	66/1096	150/8380	3.36	4.70e-21	9.09e-19	150
GO:1901987	GO:1901987	regulation of cell cycle phase transition	64/1096	146/8380	3.35	2.41e-20	4.36e-18	146
GO:0007346	GO:0007346	regulation of mitotic cell cycle	86/1096	237/8380	2.77	2.54e-20	4.36e-18	237
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	60/1096	131/8380	3.50	2.57e-20	4.36e-18	131
GO:0044839	GO:0044839	cell cycle G2/M phase transition	44/1096	82/8380	4.10	1.43e-18	2.34e-16	82
GO:0000075	GO:0000075	cell cycle checkpoint	41/1096	73/8380	4.29	2.32e-18	3.65e-16	73
GO:0033045	GO:0033045	regulation of sister chromatid segregation	26/1096	32/8380	6.21	3.40e-18	5.17e-16	32
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	41/1096	75/8380	4.18	8.82e-18	1.29e-15	75
GO:0032392	GO:0032392	DNA geometric change	23/1096	27/8380	6.51	4.07e-17	5.76e-15	27
GO:0051304	GO:0051304	chromosome separation	28/1096	39/8380	5.49	5.34e-17	7.32e-15	39
GO:0007088	GO:0007088	regulation of mitotic nuclear division	44/1096	90/8380	3.74	1.48e-16	1.97e-14	90
GO:0006310	GO:0006310	DNA recombination	47/1096	101/8380	3.56	1.62e-16	2.08e-14	101
GO:0044843	GO:0044843	cell cycle G1/S phase transition	49/1096	109/8380	3.44	2.11e-16	2.64e-14	109
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	22/1096	26/8380	6.47	2.70e-16	3.10e-14	26
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	22/1096	26/8380	6.47	2.70e-16	3.10e-14	26
GO:0051306	GO:0051306	mitotic sister chromatid separation	22/1096	26/8380	6.47	2.70e-16	3.10e-14	26
GO:0032508	GO:0032508	DNA duplex unwinding	20/1096	22/8380	6.95	3.28e-16	3.63e-14	22
GO:0010948	GO:0010948	negative regulation of cell cycle process	49/1096	110/8380	3.41	3.34e-16	3.63e-14	110
GO:0007051	GO:0007051	spindle organization	35/1096	62/8380	4.32	5.91e-16	6.18e-14	62
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	46/1096	100/8380	3.52	5.97e-16	6.18e-14	100
GO:1905818	GO:1905818	regulation of chromosome separation	22/1096	27/8380	6.23	1.28e-15	1.29e-13	27
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	21/1096	25/8380	6.42	1.78e-15	1.76e-13	25
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	34/1096	61/8380	4.26	2.62e-15	2.54e-13	61
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	31/1096	52/8380	4.56	3.41e-15	3.22e-13	52
GO:0051783	GO:0051783	regulation of nuclear division	45/1096	101/8380	3.41	5.47e-15	5.05e-13	101
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	21/1096	26/8380	6.18	8.11e-15	7.33e-13	26
GO:0045786	GO:0045786	negative regulation of cell cycle	76/1096	236/8380	2.46	8.96e-15	7.89e-13	236
GO:0006302	GO:0006302	double-strand break repair	39/1096	80/8380	3.73	9.10e-15	7.89e-13	80
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	20/1096	24/8380	6.37	1.16e-14	9.86e-13	24
GO:0034502	GO:0034502	protein localization to chromosome	19/1096	22/8380	6.60	1.49e-14	1.24e-12	22
GO:0045787	GO:0045787	positive regulation of cell cycle	65/1096	189/8380	2.63	2.55e-14	2.08e-12	189
GO:0090068	GO:0090068	positive regulation of cell cycle process	52/1096	133/8380	2.99	2.95e-14	2.37e-12	133
GO:0051321	GO:0051321	meiotic cell cycle	51/1096	130/8380	3.00	4.47e-14	3.52e-12	130
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	32/1096	59/8380	4.15	4.96e-14	3.84e-12	59
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	20/1096	25/8380	6.12	5.09e-14	3.86e-12	25
GO:0031570	GO:0031570	DNA integrity checkpoint	29/1096	50/8380	4.43	7.34e-14	5.47e-12	50
GO:0007052	GO:0007052	mitotic spindle organization	27/1096	44/8380	4.69	7.76e-14	5.69e-12	44
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	37/1096	77/8380	3.67	7.94e-14	5.72e-12	77
GO:0033044	GO:0033044	regulation of chromosome organization	44/1096	104/8380	3.23	1.07e-13	7.59e-12	104
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	29/1096	52/8380	4.26	2.96e-13	2.06e-11	52
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	14/1096	14/8380	7.65	3.99e-13	2.73e-11	14
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	34/1096	70/8380	3.71	5.53e-13	3.73e-11	70
GO:0006270	GO:0006270	DNA replication initiation	15/1096	16/8380	7.17	7.25e-13	4.81e-11	16
GO:2001251	GO:2001251	negative regulation of chromosome organization	26/1096	45/8380	4.42	1.66e-12	1.08e-10	45
GO:0007017	GO:0007017	microtubule-based process	91/1096	335/8380	2.08	1.68e-12	1.08e-10	335
GO:0007062	GO:0007062	sister chromatid cohesion	18/1096	23/8380	5.98	1.95e-12	1.24e-10	23
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	44/1096	112/8380	3.00	2.40e-12	1.50e-10	112
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/1096	19/8380	6.44	4.38e-12	2.66e-10	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/1096	19/8380	6.44	4.38e-12	2.66e-10	19
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	15/1096	17/8380	6.75	5.41e-12	3.24e-10	17
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	26/1096	48/8380	4.14	1.26e-11	7.41e-10	48
GO:1903046	GO:1903046	meiotic cell cycle process	41/1096	105/8380	2.99	1.71e-11	9.93e-10	105
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/1096	18/8380	6.37	2.86e-11	1.60e-09	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/1096	18/8380	6.37	2.86e-11	1.60e-09	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/1096	18/8380	6.37	2.86e-11	1.60e-09	18
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	24/1096	43/8380	4.27	3.33e-11	1.81e-09	43
GO:0000725	GO:0000725	recombinational repair	24/1096	43/8380	4.27	3.33e-11	1.81e-09	43
GO:0006323	GO:0006323	DNA packaging	38/1096	96/8380	3.03	5.85e-11	3.15e-09	96
GO:0000226	GO:0000226	microtubule cytoskeleton organization	71/1096	253/8380	2.15	1.06e-10	5.65e-09	253
GO:0044786	GO:0044786	cell cycle DNA replication	15/1096	19/8380	6.04	1.19e-10	6.25e-09	19
GO:0006325	GO:0006325	chromatin organization	74/1096	270/8380	2.10	1.42e-10	7.37e-09	270
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	18/1096	27/8380	5.10	1.61e-10	8.26e-09	27
GO:0051383	GO:0051383	kinetochore organization	11/1096	11/8380	7.65	1.83e-10	9.00e-09	11
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	11/1096	11/8380	7.65	1.83e-10	9.00e-09	11
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	14/1096	17/8380	6.30	1.84e-10	9.00e-09	17
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	14/1096	17/8380	6.30	1.84e-10	9.00e-09	17
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	22/1096	40/8380	4.21	3.27e-10	1.58e-08	40
GO:0051310	GO:0051310	metaphase plate congression	15/1096	20/8380	5.73	4.19e-10	2.00e-08	20
GO:0010639	GO:0010639	negative regulation of organelle organization	52/1096	167/8380	2.38	6.67e-10	3.15e-08	167
GO:0140013	GO:0140013	meiotic nuclear division	37/1096	99/8380	2.86	7.27e-10	3.40e-08	99
GO:0051784	GO:0051784	negative regulation of nuclear division	18/1096	30/8380	4.59	2.02e-09	9.31e-08	30
GO:0000077	GO:0000077	DNA damage checkpoint	22/1096	43/8380	3.91	2.05e-09	9.38e-08	43
GO:0065004	GO:0065004	protein-DNA complex assembly	35/1096	96/8380	2.79	4.52e-09	2.04e-07	96
GO:0051225	GO:0051225	spindle assembly	19/1096	35/8380	4.15	7.23e-09	3.14e-07	35
GO:0007080	GO:0007080	mitotic metaphase plate congression	12/1096	15/8380	6.12	7.38e-09	3.14e-07	15
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/1096	15/8380	6.12	7.38e-09	3.14e-07	15
GO:0031577	GO:0031577	spindle checkpoint	12/1096	15/8380	6.12	7.38e-09	3.14e-07	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/1096	15/8380	6.12	7.38e-09	3.14e-07	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/1096	15/8380	6.12	7.38e-09	3.14e-07	15
GO:0071824	GO:0071824	protein-DNA complex subunit organization	37/1096	107/8380	2.64	8.74e-09	3.68e-07	107
GO:0000281	GO:0000281	mitotic cytokinesis	17/1096	29/8380	4.48	9.41e-09	3.92e-07	29
GO:0050000	GO:0050000	chromosome localization	16/1096	26/8380	4.71	9.71e-09	3.97e-07	26
GO:0051303	GO:0051303	establishment of chromosome localization	16/1096	26/8380	4.71	9.71e-09	3.97e-07	26
GO:0051052	GO:0051052	regulation of DNA metabolic process	45/1096	146/8380	2.36	1.36e-08	5.48e-07	146
GO:0051984	GO:0051984	positive regulation of chromosome segregation	10/1096	11/8380	6.95	1.37e-08	5.50e-07	11
GO:1902750	GO:1902750	negative regulation of cell cycle G2/M phase transition	14/1096	21/8380	5.10	1.89e-08	7.49e-07	21
GO:0006275	GO:0006275	regulation of DNA replication	19/1096	37/8380	3.93	2.43e-08	9.54e-07	37
GO:0033260	GO:0033260	nuclear DNA replication	12/1096	16/8380	5.73	2.60e-08	1.01e-06	16
GO:0000910	GO:0000910	cytokinesis	25/1096	60/8380	3.19	3.39e-08	1.31e-06	60
GO:0043161	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	35/1096	103/8380	2.60	3.67e-08	1.41e-06	103
GO:0007098	GO:0007098	centrosome cycle	19/1096	38/8380	3.82	4.26e-08	1.60e-06	38
GO:0044774	GO:0044774	mitotic DNA integrity checkpoint	19/1096	38/8380	3.82	4.26e-08	1.60e-06	38
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	11/1096	14/8380	6.01	4.57e-08	1.70e-06	14
GO:0034508	GO:0034508	centromere complex assembly	15/1096	25/8380	4.59	4.64e-08	1.72e-06	25
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	28/1096	74/8380	2.89	6.30e-08	2.31e-06	74
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	18/1096	36/8380	3.82	9.72e-08	3.53e-06	36
GO:0032200	GO:0032200	telomere organization	21/1096	47/8380	3.42	9.98e-08	3.59e-06	47
GO:0061982	GO:0061982	meiosis I cell cycle process	26/1096	67/8380	2.97	1.03e-07	3.66e-06	67
GO:0000079	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	22/1096	51/8380	3.30	1.07e-07	3.77e-06	51
GO:0045132	GO:0045132	meiotic chromosome segregation	22/1096	51/8380	3.30	1.07e-07	3.77e-06	51
GO:0072401	GO:0072401	signal transduction involved in DNA integrity checkpoint	15/1096	27/8380	4.25	1.91e-07	6.60e-06	27
GO:0072422	GO:0072422	signal transduction involved in DNA damage checkpoint	15/1096	27/8380	4.25	1.91e-07	6.60e-06	27
GO:0090307	GO:0090307	mitotic spindle assembly	13/1096	21/8380	4.73	2.25e-07	7.73e-06	21
GO:0031497	GO:0031497	chromatin assembly	28/1096	78/8380	2.74	2.31e-07	7.86e-06	78
GO:0036297	GO:0036297	interstrand cross-link repair	10/1096	13/8380	5.88	2.77e-07	9.36e-06	13
GO:0006511	GO:0006511	ubiquitin-dependent protein catabolic process	43/1096	151/8380	2.18	3.48e-07	1.17e-05	151
GO:0072395	GO:0072395	signal transduction involved in cell cycle checkpoint	15/1096	28/8380	4.10	3.62e-07	1.20e-05	28
GO:1904029	GO:1904029	regulation of cyclin-dependent protein kinase activity	22/1096	54/8380	3.12	3.63e-07	1.20e-05	54
GO:0006333	GO:0006333	chromatin assembly or disassembly	29/1096	84/8380	2.64	3.69e-07	1.21e-05	84
GO:0033365	GO:0033365	protein localization to organelle	66/1096	275/8380	1.84	3.91e-07	1.27e-05	275
GO:0006334	GO:0006334	nucleosome assembly	26/1096	71/8380	2.80	3.96e-07	1.28e-05	71
GO:0010498	GO:0010498	proteasomal protein catabolic process	36/1096	117/8380	2.35	4.01e-07	1.28e-05	117
GO:0034728	GO:0034728	nucleosome organization	28/1096	80/8380	2.68	4.24e-07	1.34e-05	80
GO:0090329	GO:0090329	regulation of DNA-dependent DNA replication	11/1096	16/8380	5.26	4.26e-07	1.34e-05	16
GO:0000723	GO:0000723	telomere maintenance	18/1096	39/8380	3.53	4.53e-07	1.42e-05	39
GO:0031023	GO:0031023	microtubule organizing center organization	19/1096	43/8380	3.38	5.04e-07	1.56e-05	43
GO:0019941	GO:0019941	modification-dependent protein catabolic process	43/1096	153/8380	2.15	5.19e-07	1.60e-05	153
GO:0042770	GO:0042770	signal transduction in response to DNA damage	21/1096	51/8380	3.15	5.41e-07	1.65e-05	51
GO:0043632	GO:0043632	modification-dependent macromolecule catabolic process	43/1096	154/8380	2.13	6.31e-07	1.92e-05	154
GO:0007127	GO:0007127	meiosis I	24/1096	64/8380	2.87	6.68e-07	2.01e-05	64
GO:0045005	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	10/1096	14/8380	5.46	8.57e-07	2.56e-05	14
GO:0010972	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	11/1096	17/8380	4.95	1.06e-06	3.16e-05	17
GO:0030261	GO:0030261	chromosome condensation	12/1096	20/8380	4.59	1.08e-06	3.20e-05	20
GO:0070507	GO:0070507	regulation of microtubule cytoskeleton organization	29/1096	88/8380	2.52	1.12e-06	3.28e-05	88
GO:0031297	GO:0031297	replication fork processing	9/1096	12/8380	5.73	1.65e-06	4.80e-05	12
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	12/1096	21/8380	4.37	2.23e-06	6.40e-05	21
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	12/1096	21/8380	4.37	2.23e-06	6.40e-05	21
GO:0070317	GO:0070317	negative regulation of G0 to G1 transition	8/1096	10/8380	6.12	2.95e-06	8.41e-05	10
GO:2001020	GO:2001020	regulation of response to DNA damage stimulus	26/1096	79/8380	2.52	4.10e-06	1.16e-04	79
GO:0031055	GO:0031055	chromatin remodeling at centromere	12/1096	22/8380	4.17	4.32e-06	1.22e-04	22
GO:0051603	GO:0051603	proteolysis involved in cellular protein catabolic process	47/1096	187/8380	1.92	4.98e-06	1.39e-04	187
GO:0046605	GO:0046605	regulation of centrosome cycle	11/1096	19/8380	4.43	5.05e-06	1.40e-04	19
GO:1902806	GO:1902806	regulation of cell cycle G1/S phase transition	23/1096	67/8380	2.62	6.59e-06	1.82e-04	67
GO:0044773	GO:0044773	mitotic DNA damage checkpoint	15/1096	34/8380	3.37	8.32e-06	2.28e-04	34
GO:0031572	GO:0031572	G2 DNA damage checkpoint	8/1096	11/8380	5.56	9.56e-06	2.59e-04	11
GO:0044818	GO:0044818	mitotic G2/M transition checkpoint	8/1096	11/8380	5.56	9.56e-06	2.59e-04	11
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	11/1096	20/8380	4.21	9.90e-06	2.61e-04	20
GO:0061641	GO:0061641	CENP-A containing chromatin organization	11/1096	20/8380	4.21	9.90e-06	2.61e-04	20
GO:0090342	GO:0090342	regulation of cell aging	11/1096	20/8380	4.21	9.90e-06	2.61e-04	20
GO:1902751	GO:1902751	positive regulation of cell cycle G2/M phase transition	11/1096	20/8380	4.21	9.90e-06	2.61e-04	20
GO:2000779	GO:2000779	regulation of double-strand break repair	13/1096	27/8380	3.68	1.04e-05	2.72e-04	27
GO:2000772	GO:2000772	regulation of cellular senescence	10/1096	17/8380	4.50	1.14e-05	2.98e-04	17
GO:0007569	GO:0007569	cell aging	17/1096	43/8380	3.02	1.26e-05	3.25e-04	43
GO:0000726	GO:0000726	non-recombinational repair	12/1096	24/8380	3.82	1.40e-05	3.59e-04	24
GO:0043486	GO:0043486	histone exchange	12/1096	24/8380	3.82	1.40e-05	3.59e-04	24
GO:0072331	GO:0072331	signal transduction by p53 class mediator	26/1096	84/8380	2.37	1.44e-05	3.66e-04	84
GO:0090398	GO:0090398	cellular senescence	13/1096	28/8380	3.55	1.70e-05	4.31e-04	28
GO:0007018	GO:0007018	microtubule-based movement	34/1096	125/8380	2.08	1.72e-05	4.32e-04	125
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	17/1096	44/8380	2.95	1.80e-05	4.49e-04	44
GO:0006338	GO:0006338	chromatin remodeling	20/1096	57/8380	2.68	1.81e-05	4.49e-04	57
GO:0010971	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	10/1096	18/8380	4.25	2.27e-05	5.62e-04	18
GO:0032886	GO:0032886	regulation of microtubule-based process	30/1096	106/8380	2.16	2.32e-05	5.70e-04	106
GO:0007131	GO:0007131	reciprocal meiotic recombination	12/1096	25/8380	3.67	2.38e-05	5.78e-04	25
GO:0035825	GO:0035825	homologous recombination	12/1096	25/8380	3.67	2.38e-05	5.78e-04	25
GO:2000045	GO:2000045	regulation of G1/S transition of mitotic cell cycle	20/1096	58/8380	2.64	2.43e-05	5.86e-04	58
GO:0000018	GO:0000018	regulation of DNA recombination	16/1096	41/8380	2.98	2.74e-05	6.58e-04	41
GO:0070925	GO:0070925	organelle assembly	67/1096	316/8380	1.62	2.96e-05	7.06e-04	316
GO:2001252	GO:2001252	positive regulation of chromosome organization	18/1096	50/8380	2.75	3.17e-05	7.44e-04	50
GO:0006303	GO:0006303	double-strand break repair via nonhomologous end joining	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:0072413	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:0072431	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:1902400	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:1902402	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:1902403	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	11/1096	22/8380	3.82	3.24e-05	7.44e-04	22
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	25/1096	83/8380	2.30	3.51e-05	8.02e-04	83
GO:0006282	GO:0006282	regulation of DNA repair	16/1096	42/8380	2.91	3.89e-05	8.81e-04	42
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	12/1096	26/8380	3.53	3.90e-05	8.81e-04	26
GO:2001021	GO:2001021	negative regulation of response to DNA damage stimulus	13/1096	30/8380	3.31	4.23e-05	9.48e-04	30
GO:0051298	GO:0051298	centrosome duplication	10/1096	19/8380	4.02	4.24e-05	9.48e-04	19
GO:0044257	GO:0044257	cellular protein catabolic process	48/1096	208/8380	1.76	4.50e-05	1.00e-03	208
GO:0000729	GO:0000729	DNA double-strand break processing	7/1096	10/8380	5.35	5.38e-05	1.18e-03	10
GO:2000780	GO:2000780	negative regulation of double-strand break repair	7/1096	10/8380	5.35	5.38e-05	1.18e-03	10
GO:0030330	GO:0030330	DNA damage response, signal transduction by p53 class mediator	16/1096	43/8380	2.85	5.46e-05	1.18e-03	43
GO:0031571	GO:0031571	mitotic G1 DNA damage checkpoint	11/1096	23/8380	3.66	5.47e-05	1.18e-03	23
GO:0044783	GO:0044783	G1 DNA damage checkpoint	11/1096	23/8380	3.66	5.47e-05	1.18e-03	23
GO:0044819	GO:0044819	mitotic G1/S transition checkpoint	11/1096	23/8380	3.66	5.47e-05	1.18e-03	23
GO:0045023	GO:0045023	G0 to G1 transition	8/1096	13/8380	4.71	5.84e-05	1.25e-03	13
GO:0070316	GO:0070316	regulation of G0 to G1 transition	8/1096	13/8380	4.71	5.84e-05	1.25e-03	13
GO:0032465	GO:0032465	regulation of cytokinesis	14/1096	35/8380	3.06	6.31e-05	1.34e-03	35
GO:0010569	GO:0010569	regulation of double-strand break repair via homologous recombination	9/1096	17/8380	4.05	9.83e-05	2.08e-03	17
GO:0007050	GO:0007050	cell cycle arrest	29/1096	109/8380	2.03	1.08e-04	2.28e-03	109
GO:0006977	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	10/1096	21/8380	3.64	1.26e-04	2.64e-03	21
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	14/1096	37/8380	2.89	1.29e-04	2.68e-03	37
GO:0045737	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	7/1096	11/8380	4.87	1.31e-04	2.71e-03	11
GO:0045738	GO:0045738	negative regulation of DNA repair	7/1096	11/8380	4.87	1.31e-04	2.71e-03	11
GO:0010638	GO:0010638	positive regulation of organelle organization	55/1096	259/8380	1.62	1.45e-04	2.98e-03	259
GO:0006890	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	9/1096	18/8380	3.82	1.74e-04	3.54e-03	18
GO:0007143	GO:0007143	female meiotic nuclear division	9/1096	18/8380	3.82	1.74e-04	3.54e-03	18
GO:0044380	GO:0044380	protein localization to cytoskeleton	10/1096	22/8380	3.48	2.05e-04	4.14e-03	22
GO:1902807	GO:1902807	negative regulation of cell cycle G1/S phase transition	15/1096	43/8380	2.67	2.16e-04	4.34e-03	43
GO:0090344	GO:0090344	negative regulation of cell aging	8/1096	15/8380	4.08	2.29e-04	4.59e-03	15
GO:2000773	GO:2000773	negative regulation of cellular senescence	7/1096	12/8380	4.46	2.79e-04	5.55e-03	12
GO:0071897	GO:0071897	DNA biosynthetic process	18/1096	58/8380	2.37	2.83e-04	5.60e-03	58
GO:0072698	GO:0072698	protein localization to microtubule cytoskeleton	9/1096	19/8380	3.62	2.92e-04	5.75e-03	19
GO:2000134	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	14/1096	40/8380	2.68	3.35e-04	6.56e-03	40
GO:0071156	GO:0071156	regulation of cell cycle arrest	15/1096	45/8380	2.55	3.81e-04	7.39e-03	45
GO:0031146	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	8/1096	16/8380	3.82	4.06e-04	7.84e-03	16
GO:0071158	GO:0071158	positive regulation of cell cycle arrest	12/1096	32/8380	2.87	4.29e-04	8.25e-03	32
GO:0002200	GO:0002200	somatic diversification of immune receptors	11/1096	28/8380	3.00	4.66e-04	8.88e-03	28
GO:0051445	GO:0051445	regulation of meiotic cell cycle	11/1096	28/8380	3.00	4.66e-04	8.88e-03	28
GO:0045740	GO:0045740	positive regulation of DNA replication	9/1096	20/8380	3.44	4.70e-04	8.92e-03	20
GO:0000209	GO:0000209	protein polyubiquitination	22/1096	81/8380	2.08	5.22e-04	9.85e-03	81
GO:0010824	GO:0010824	regulation of centrosome duplication	7/1096	13/8380	4.12	5.37e-04	1.01e-02	13
GO:0048193	GO:0048193	Golgi vesicle transport	25/1096	98/8380	1.95	6.29e-04	1.18e-02	98
GO:0040001	GO:0040001	establishment of mitotic spindle localization	6/1096	10/8380	4.59	6.48e-04	1.20e-02	10
GO:0098534	GO:0098534	centriole assembly	6/1096	10/8380	4.59	6.48e-04	1.20e-02	10
GO:0051640	GO:0051640	organelle localization	56/1096	281/8380	1.52	6.88e-04	1.27e-02	281
GO:0007156	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	34/1096	149/8380	1.74	6.95e-04	1.28e-02	149
GO:0006342	GO:0006342	chromatin silencing	13/1096	38/8380	2.62	6.98e-04	1.28e-02	38
GO:0000731	GO:0000731	DNA synthesis involved in DNA repair	7/1096	14/8380	3.82	9.54e-04	1.70e-02	14
GO:0006284	GO:0006284	base-excision repair	7/1096	14/8380	3.82	9.54e-04	1.70e-02	14
GO:0051307	GO:0051307	meiotic chromosome separation	7/1096	14/8380	3.82	9.54e-04	1.70e-02	14
GO:1904031	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	7/1096	14/8380	3.82	9.54e-04	1.70e-02	14
GO:0002562	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	10/1096	26/8380	2.94	1.03e-03	1.82e-02	26
GO:0016444	GO:0016444	somatic cell DNA recombination	10/1096	26/8380	2.94	1.03e-03	1.82e-02	26
GO:0051053	GO:0051053	negative regulation of DNA metabolic process	15/1096	49/8380	2.34	1.05e-03	1.85e-02	49
GO:0045910	GO:0045910	negative regulation of DNA recombination	8/1096	18/8380	3.40	1.08e-03	1.89e-02	18
GO:0051438	GO:0051438	regulation of ubiquitin-protein transferase activity	8/1096	18/8380	3.40	1.08e-03	1.89e-02	18
GO:0097711	GO:0097711	ciliary basal body-plasma membrane docking	8/1096	18/8380	3.40	1.08e-03	1.89e-02	18
GO:0006611	GO:0006611	protein export from nucleus	11/1096	31/8380	2.71	1.27e-03	2.17e-02	31
GO:0010458	GO:0010458	exit from mitosis	6/1096	11/8380	4.17	1.27e-03	2.17e-02	11
GO:0031935	GO:0031935	regulation of chromatin silencing	6/1096	11/8380	4.17	1.27e-03	2.17e-02	11
GO:1904666	GO:1904666	regulation of ubiquitin protein ligase activity	6/1096	11/8380	4.17	1.27e-03	2.17e-02	11
GO:0045840	GO:0045840	positive regulation of mitotic nuclear division	10/1096	27/8380	2.83	1.44e-03	2.45e-02	27
GO:0006289	GO:0006289	nucleotide-excision repair	7/1096	15/8380	3.57	1.59e-03	2.69e-02	15
GO:0032467	GO:0032467	positive regulation of cytokinesis	8/1096	19/8380	3.22	1.66e-03	2.80e-02	19
GO:0051168	GO:0051168	nuclear export	11/1096	32/8380	2.63	1.71e-03	2.86e-02	32
GO:1903320	GO:1903320	regulation of protein modification by small protein conjugation or removal	19/1096	72/8380	2.02	1.78e-03	2.97e-02	72
GO:0051651	GO:0051651	maintenance of location in cell	13/1096	42/8380	2.37	1.99e-03	3.32e-02	42
GO:0031396	GO:0031396	regulation of protein ubiquitination	18/1096	68/8380	2.02	2.24e-03	3.71e-02	68
GO:0006301	GO:0006301	postreplication repair	6/1096	12/8380	3.82	2.26e-03	3.72e-02	12
GO:0031062	GO:0031062	positive regulation of histone methylation	6/1096	12/8380	3.82	2.26e-03	3.72e-02	12
GO:0016567	GO:0016567	protein ubiquitination	47/1096	239/8380	1.50	2.38e-03	3.89e-02	239
GO:0051169	GO:0051169	nuclear transport	23/1096	96/8380	1.83	2.50e-03	4.05e-02	96
GO:0044003	GO:0044003	modification by symbiont of host morphology or physiology	7/1096	16/8380	3.35	2.51e-03	4.05e-02	16
GO:0051653	GO:0051653	spindle localization	7/1096	16/8380	3.35	2.51e-03	4.05e-02	16

Factor 18 : 587 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0002250	GO:0002250	adaptive immune response	126/1012	270/8380	3.86	6.42e-47	1.91e-43	270
GO:0050778	GO:0050778	positive regulation of immune response	167/1012	443/8380	3.12	1.03e-46	1.91e-43	443
GO:0046649	GO:0046649	lymphocyte activation	160/1012	416/8380	3.18	5.05e-46	6.25e-43	416
GO:0019221	GO:0019221	cytokine-mediated signaling pathway	165/1012	465/8380	2.94	4.53e-42	4.21e-39	465
GO:0009615	GO:0009615	response to virus	89/1012	161/8380	4.58	9.52e-41	7.08e-38	161
GO:0051607	GO:0051607	defense response to virus	74/1012	115/8380	5.33	2.14e-40	1.32e-37	115
GO:0042110	GO:0042110	T cell activation	123/1012	306/8380	3.33	1.77e-37	9.40e-35	306
GO:0098542	GO:0098542	defense response to other organism	105/1012	259/8380	3.36	2.23e-32	1.04e-29	259
GO:0002253	GO:0002253	activation of immune response	119/1012	321/8380	3.07	3.11e-32	1.28e-29	321
GO:0002757	GO:0002757	immune response-activating signal transduction	104/1012	269/8380	3.20	5.53e-30	2.06e-27	269
GO:0002697	GO:0002697	regulation of immune effector process	99/1012	248/8380	3.31	6.83e-30	2.31e-27	248
GO:0002764	GO:0002764	immune response-regulating signaling pathway	108/1012	291/8380	3.07	2.58e-29	8.01e-27	291
GO:0051249	GO:0051249	regulation of lymphocyte activation	104/1012	276/8380	3.12	6.99e-29	2.00e-26	276
GO:0002694	GO:0002694	regulation of leukocyte activation	116/1012	334/8380	2.88	2.00e-28	5.31e-26	334
GO:0002429	GO:0002429	immune response-activating cell surface receptor signaling pathway	81/1012	185/8380	3.63	7.62e-28	1.89e-25	185
GO:0060337	GO:0060337	type I interferon signaling pathway	40/1012	51/8380	6.49	1.20e-27	2.63e-25	51
GO:0071357	GO:0071357	cellular response to type I interferon	40/1012	51/8380	6.49	1.20e-27	2.63e-25	51
GO:0034341	GO:0034341	response to interferon-gamma	67/1012	135/8380	4.11	3.88e-27	8.01e-25	135
GO:0034340	GO:0034340	response to type I interferon	40/1012	52/8380	6.37	4.62e-27	9.03e-25	52
GO:0002768	GO:0002768	immune response-regulating cell surface receptor signaling pathway	85/1012	207/8380	3.40	8.95e-27	1.66e-24	207
GO:0050863	GO:0050863	regulation of T cell activation	87/1012	217/8380	3.32	1.70e-26	3.01e-24	217
GO:0031347	GO:0031347	regulation of defense response	135/1012	445/8380	2.51	2.39e-26	4.04e-24	445
GO:0050865	GO:0050865	regulation of cell activation	118/1012	362/8380	2.70	4.38e-26	7.07e-24	362
GO:0001816	GO:0001816	cytokine production	137/1012	459/8380	2.47	5.80e-26	8.98e-24	459
GO:0001817	GO:0001817	regulation of cytokine production	127/1012	415/8380	2.53	3.58e-25	5.32e-23	415
GO:0007159	GO:0007159	leukocyte cell-cell adhesion	88/1012	231/8380	3.15	6.47e-25	9.25e-23	231
GO:0045088	GO:0045088	regulation of innate immune response	84/1012	215/8380	3.24	1.08e-24	1.48e-22	215
GO:0071346	GO:0071346	cellular response to interferon-gamma	60/1012	121/8380	4.11	2.21e-24	2.93e-22	121
GO:0002449	GO:0002449	lymphocyte mediated immunity	70/1012	161/8380	3.60	5.85e-24	7.49e-22	161
GO:0030098	GO:0030098	lymphocyte differentiation	83/1012	217/8380	3.17	1.11e-23	1.38e-21	217
GO:0002443	GO:0002443	leukocyte mediated immunity	128/1012	435/8380	2.44	1.25e-23	1.50e-21	435
GO:1903037	GO:1903037	regulation of leukocyte cell-cell adhesion	80/1012	207/8380	3.20	3.40e-23	3.94e-21	207
GO:0002460	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	71/1012	172/8380	3.42	1.15e-22	1.29e-20	172
GO:0002521	GO:0002521	leukocyte differentiation	101/1012	320/8380	2.61	3.34e-21	3.65e-19	320
GO:0002696	GO:0002696	positive regulation of leukocyte activation	78/1012	212/8380	3.05	4.44e-21	4.71e-19	212
GO:0016032	GO:0016032	viral process	88/1012	259/8380	2.81	5.95e-21	6.15e-19	259
GO:0050851	GO:0050851	antigen receptor-mediated signaling pathway	55/1012	118/8380	3.86	8.29e-21	8.33e-19	118
GO:0030217	GO:0030217	T cell differentiation	66/1012	162/8380	3.37	9.07e-21	8.87e-19	162
GO:0051251	GO:0051251	positive regulation of lymphocyte activation	70/1012	180/8380	3.22	1.36e-20	1.29e-18	180
GO:0050867	GO:0050867	positive regulation of cell activation	79/1012	220/8380	2.97	1.41e-20	1.31e-18	220
GO:0044419	GO:0044419	interspecies interaction between organisms	99/1012	319/8380	2.57	3.34e-20	3.03e-18	319
GO:0050870	GO:0050870	positive regulation of T cell activation	61/1012	147/8380	3.44	9.26e-20	8.16e-18	147
GO:0045071	GO:0045071	negative regulation of viral genome replication	26/1012	31/8380	6.95	9.44e-20	8.16e-18	31
GO:0046631	GO:0046631	alpha-beta T cell activation	48/1012	97/8380	4.10	1.10e-19	9.29e-18	97
GO:1903039	GO:1903039	positive regulation of leukocyte cell-cell adhesion	63/1012	157/8380	3.32	1.82e-19	1.50e-17	157
GO:1903901	GO:1903901	negative regulation of viral life cycle	29/1012	39/8380	6.16	3.16e-19	2.56e-17	39
GO:0002683	GO:0002683	negative regulation of immune system process	90/1012	284/8380	2.62	4.20e-19	3.32e-17	284
GO:0060333	GO:0060333	interferon-gamma-mediated signaling pathway	37/1012	62/8380	4.94	4.30e-19	3.33e-17	62
GO:0044403	GO:0044403	symbiont process	91/1012	290/8380	2.60	5.50e-19	4.17e-17	290
GO:0070661	GO:0070661	leukocyte proliferation	71/1012	196/8380	3.00	7.74e-19	5.76e-17	196
GO:0002703	GO:0002703	regulation of leukocyte mediated immunity	56/1012	134/8380	3.46	2.09e-18	1.53e-16	134
GO:0043900	GO:0043900	regulation of multi-organism process	69/1012	191/8380	2.99	2.91e-18	2.08e-16	191
GO:0019058	GO:0019058	viral life cycle	56/1012	136/8380	3.41	4.78e-18	3.35e-16	136
GO:0001819	GO:0001819	positive regulation of cytokine production	86/1012	274/8380	2.60	5.36e-18	3.69e-16	274
GO:0045089	GO:0045089	positive regulation of innate immune response	67/1012	184/8380	3.02	5.67e-18	3.83e-16	184
GO:0030097	GO:0030097	hemopoiesis	124/1012	477/8380	2.15	6.39e-18	4.24e-16	477
GO:0046651	GO:0046651	lymphocyte proliferation	66/1012	181/8380	3.02	9.30e-18	6.07e-16	181
GO:1903900	GO:1903900	regulation of viral life cycle	36/1012	63/8380	4.73	9.58e-18	6.14e-16	63
GO:0032943	GO:0032943	mononuclear cell proliferation	66/1012	183/8380	2.99	1.80e-17	1.13e-15	183
GO:0002819	GO:0002819	regulation of adaptive immune response	48/1012	107/8380	3.71	1.84e-17	1.14e-15	107
GO:0045069	GO:0045069	regulation of viral genome replication	29/1012	43/8380	5.58	2.41e-17	1.47e-15	43
GO:0043901	GO:0043901	negative regulation of multi-organism process	43/1012	89/8380	4.00	2.90e-17	1.74e-15	89
GO:0002699	GO:0002699	positive regulation of immune effector process	56/1012	141/8380	3.29	3.45e-17	2.04e-15	141
GO:0019079	GO:0019079	viral genome replication	32/1012	53/8380	5.00	6.81e-17	3.94e-15	53
GO:0048525	GO:0048525	negative regulation of viral process	30/1012	47/8380	5.29	6.89e-17	3.94e-15	47
GO:0070663	GO:0070663	regulation of leukocyte proliferation	60/1012	162/8380	3.07	1.28e-16	7.23e-15	162
GO:0001909	GO:0001909	leukocyte mediated cytotoxicity	40/1012	81/8380	4.09	1.43e-16	7.93e-15	81
GO:0002706	GO:0002706	regulation of lymphocyte mediated immunity	45/1012	100/8380	3.73	1.64e-16	8.95e-15	100
GO:0022409	GO:0022409	positive regulation of cell-cell adhesion	65/1012	186/8380	2.89	1.98e-16	1.07e-14	186
GO:0002822	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	44/1012	97/8380	3.76	2.47e-16	1.31e-14	97
GO:0022407	GO:0022407	regulation of cell-cell adhesion	83/1012	276/8380	2.49	3.66e-16	1.92e-14	276
GO:0002831	GO:0002831	regulation of response to biotic stimulus	35/1012	66/8380	4.39	6.60e-16	3.41e-14	66
GO:0031341	GO:0031341	regulation of cell killing	36/1012	70/8380	4.26	9.16e-16	4.66e-14	70
GO:0045619	GO:0045619	regulation of lymphocyte differentiation	47/1012	112/8380	3.47	9.97e-16	5.01e-14	112
GO:0001910	GO:0001910	regulation of leukocyte mediated cytotoxicity	34/1012	64/8380	4.40	1.61e-15	7.97e-14	64
GO:0002263	GO:0002263	cell activation involved in immune response	101/1012	381/8380	2.20	2.54e-15	1.24e-13	381
GO:0031349	GO:0031349	positive regulation of defense response	81/1012	275/8380	2.44	3.17e-15	1.53e-13	275
GO:0050852	GO:0050852	T cell receptor signaling pathway	40/1012	87/8380	3.81	3.25e-15	1.55e-13	87
GO:0002366	GO:0002366	leukocyte activation involved in immune response	100/1012	378/8380	2.19	4.08e-15	1.92e-13	378
GO:0050670	GO:0050670	regulation of lymphocyte proliferation	56/1012	155/8380	2.99	4.86e-15	2.26e-13	155
GO:0046634	GO:0046634	regulation of alpha-beta T cell activation	34/1012	66/8380	4.27	5.46e-15	2.51e-13	66
GO:0045580	GO:0045580	regulation of T cell differentiation	41/1012	92/8380	3.69	5.62e-15	2.55e-13	92
GO:0050792	GO:0050792	regulation of viral process	37/1012	77/8380	3.98	6.15e-15	2.76e-13	77
GO:0032944	GO:0032944	regulation of mononuclear cell proliferation	56/1012	156/8380	2.97	6.72e-15	2.97e-13	156
GO:0002821	GO:0002821	positive regulation of adaptive immune response	35/1012	70/8380	4.14	7.13e-15	3.12e-13	70
GO:0002824	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34/1012	67/8380	4.20	9.83e-15	4.25e-13	67
GO:0009617	GO:0009617	response to bacterium	102/1012	395/8380	2.14	1.20e-14	5.11e-13	395
GO:0002708	GO:0002708	positive regulation of lymphocyte mediated immunity	35/1012	71/8380	4.08	1.25e-14	5.26e-13	71
GO:0001906	GO:0001906	cell killing	45/1012	110/8380	3.39	1.28e-14	5.35e-13	110
GO:0002705	GO:0002705	positive regulation of leukocyte mediated immunity	39/1012	87/8380	3.71	2.06e-14	8.50e-13	87
GO:1902105	GO:1902105	regulation of leukocyte differentiation	59/1012	179/8380	2.73	9.95e-14	4.06e-12	179
GO:0002456	GO:0002456	T cell mediated immunity	35/1012	75/8380	3.86	1.02e-13	4.13e-12	75
GO:0042113	GO:0042113	B cell activation	48/1012	131/8380	3.03	2.46e-13	9.84e-12	131
GO:0002274	GO:0002274	myeloid leukocyte activation	93/1012	362/8380	2.13	2.72e-13	1.08e-11	362
GO:0031343	GO:0031343	positive regulation of cell killing	28/1012	52/8380	4.46	3.33e-13	1.30e-11	52
GO:0001818	GO:0001818	negative regulation of cytokine production	56/1012	169/8380	2.74	3.35e-13	1.30e-11	169
GO:0001912	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	26/1012	46/8380	4.68	5.11e-13	1.96e-11	46
GO:0042098	GO:0042098	T cell proliferation	47/1012	129/8380	3.02	5.59e-13	2.12e-11	129
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	39/1012	95/8380	3.40	6.70e-13	2.51e-11	95
GO:0050671	GO:0050671	positive regulation of lymphocyte proliferation	41/1012	104/8380	3.26	8.54e-13	3.17e-11	104
GO:0032946	GO:0032946	positive regulation of mononuclear cell proliferation	41/1012	105/8380	3.23	1.24e-12	4.53e-11	105
GO:0030155	GO:0030155	regulation of cell adhesion	108/1012	458/8380	1.95	1.24e-12	4.53e-11	458
GO:0050688	GO:0050688	regulation of defense response to virus	20/1012	29/8380	5.71	1.26e-12	4.53e-11	29
GO:1903706	GO:1903706	regulation of hemopoiesis	71/1012	251/8380	2.34	1.57e-12	5.60e-11	251
GO:0051250	GO:0051250	negative regulation of lymphocyte activation	38/1012	93/8380	3.38	1.58e-12	5.60e-11	93
GO:0035456	GO:0035456	response to interferon-beta	14/1012	15/8380	7.73	1.73e-12	6.06e-11	15
GO:0002695	GO:0002695	negative regulation of leukocyte activation	42/1012	111/8380	3.13	2.28e-12	7.91e-11	111
GO:0002228	GO:0002228	natural killer cell mediated immunity	25/1012	45/8380	4.60	2.45e-12	8.43e-11	45
GO:0070665	GO:0070665	positive regulation of leukocyte proliferation	41/1012	107/8380	3.17	2.58e-12	8.79e-11	107
GO:0042102	GO:0042102	positive regulation of T cell proliferation	34/1012	78/8380	3.61	2.64e-12	8.92e-11	78
GO:0050900	GO:0050900	leukocyte migration	83/1012	319/8380	2.15	2.75e-12	9.19e-11	319
GO:0045785	GO:0045785	positive regulation of cell adhesion	77/1012	287/8380	2.22	3.35e-12	1.11e-10	287
GO:0046632	GO:0046632	alpha-beta T cell differentiation	32/1012	71/8380	3.73	3.86e-12	1.27e-10	71
GO:0032609	GO:0032609	interferon-gamma production	36/1012	87/8380	3.43	3.93e-12	1.28e-10	87
GO:0002286	GO:0002286	T cell activation involved in immune response	29/1012	61/8380	3.94	7.63e-12	2.47e-10	61
GO:0006968	GO:0006968	cellular defense response	25/1012	47/8380	4.40	9.01e-12	2.89e-10	47
GO:0002483	GO:0002483	antigen processing and presentation of endogenous peptide antigen	12/1012	12/8380	8.28	9.08e-12	2.89e-10	12
GO:0002285	GO:0002285	lymphocyte activation involved in immune response	38/1012	98/8380	3.21	1.07e-11	3.38e-10	98
GO:0050868	GO:0050868	negative regulation of T cell activation	31/1012	70/8380	3.67	1.48e-11	4.63e-10	70
GO:0042129	GO:0042129	regulation of T cell proliferation	41/1012	114/8380	2.98	2.79e-11	8.65e-10	114
GO:0050691	GO:0050691	regulation of defense response to virus by host	15/1012	19/8380	6.54	3.73e-11	1.15e-09	19
GO:0002704	GO:0002704	negative regulation of leukocyte mediated immunity	20/1012	33/8380	5.02	4.45e-11	1.35e-09	33
GO:0045058	GO:0045058	T cell selection	20/1012	33/8380	5.02	4.45e-11	1.35e-09	33
GO:1903038	GO:1903038	negative regulation of leukocyte cell-cell adhesion	32/1012	78/8380	3.40	8.18e-11	2.45e-09	78
GO:0002715	GO:0002715	regulation of natural killer cell mediated immunity	21/1012	37/8380	4.70	8.26e-11	2.46e-09	37
GO:0045621	GO:0045621	positive regulation of lymphocyte differentiation	29/1012	66/8380	3.64	8.56e-11	2.52e-09	66
GO:0031348	GO:0031348	negative regulation of defense response	41/1012	118/8380	2.88	9.76e-11	2.85e-09	118
GO:0032479	GO:0032479	regulation of type I interferon production	23/1012	44/8380	4.33	9.90e-11	2.85e-09	44
GO:0032606	GO:0032606	type I interferon production	23/1012	44/8380	4.33	9.90e-11	2.85e-09	44
GO:0002440	GO:0002440	production of molecular mediator of immune response	40/1012	114/8380	2.91	1.17e-10	3.36e-09	114
GO:0050866	GO:0050866	negative regulation of cell activation	43/1012	128/8380	2.78	1.19e-10	3.36e-09	128
GO:0030101	GO:0030101	natural killer cell activation	23/1012	45/8380	4.23	1.80e-10	5.02e-09	45
GO:0046635	GO:0046635	positive regulation of alpha-beta T cell activation	23/1012	45/8380	4.23	1.80e-10	5.02e-09	45
GO:0043368	GO:0043368	positive T cell selection	16/1012	23/8380	5.76	1.97e-10	5.46e-09	23
GO:0002474	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	17/1012	26/8380	5.41	2.35e-10	6.47e-09	26
GO:0001913	GO:0001913	T cell mediated cytotoxicity	22/1012	42/8380	4.34	2.41e-10	6.55e-09	42
GO:0042267	GO:0042267	natural killer cell mediated cytotoxicity	22/1012	42/8380	4.34	2.41e-10	6.55e-09	42
GO:0019883	GO:0019883	antigen processing and presentation of endogenous antigen	14/1012	18/8380	6.44	2.47e-10	6.66e-09	18
GO:0070098	GO:0070098	chemokine-mediated signaling pathway	31/1012	77/8380	3.33	2.86e-10	7.65e-09	77
GO:0035710	GO:0035710	CD4-positive, alpha-beta T cell activation	27/1012	61/8380	3.67	3.14e-10	8.33e-09	61
GO:0002709	GO:0002709	regulation of T cell mediated immunity	24/1012	50/8380	3.97	3.87e-10	1.02e-08	50
GO:0032649	GO:0032649	regulation of interferon-gamma production	31/1012	78/8380	3.29	4.21e-10	1.10e-08	78
GO:0002218	GO:0002218	activation of innate immune response	44/1012	138/8380	2.64	4.91e-10	1.28e-08	138
GO:1990868	GO:1990868	response to chemokine	32/1012	83/8380	3.19	5.53e-10	1.42e-08	83
GO:1990869	GO:1990869	cellular response to chemokine	32/1012	83/8380	3.19	5.53e-10	1.42e-08	83
GO:0032729	GO:0032729	positive regulation of interferon-gamma production	24/1012	51/8380	3.90	6.48e-10	1.65e-08	51
GO:0050854	GO:0050854	regulation of antigen receptor-mediated signaling pathway	20/1012	37/8380	4.48	7.66e-10	1.94e-08	37
GO:0050777	GO:0050777	negative regulation of immune response	33/1012	89/8380	3.07	9.80e-10	2.46e-08	89
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	42/1012	131/8380	2.65	1.01e-09	2.52e-08	131
GO:0002698	GO:0002698	negative regulation of immune effector process	28/1012	68/8380	3.41	1.13e-09	2.80e-08	68
GO:0042100	GO:0042100	B cell proliferation	25/1012	56/8380	3.70	1.15e-09	2.82e-08	56
GO:0001914	GO:0001914	regulation of T cell mediated cytotoxicity	17/1012	28/8380	5.03	1.27e-09	3.11e-08	28
GO:0071216	GO:0071216	cellular response to biotic stimulus	43/1012	138/8380	2.58	1.73e-09	4.21e-08	138
GO:0045582	GO:0045582	positive regulation of T cell differentiation	25/1012	57/8380	3.63	1.81e-09	4.37e-08	57
GO:0042269	GO:0042269	regulation of natural killer cell mediated cytotoxicity	19/1012	35/8380	4.50	1.86e-09	4.46e-08	35
GO:0001773	GO:0001773	myeloid dendritic cell activation	14/1012	20/8380	5.80	2.48e-09	5.90e-08	20
GO:0002237	GO:0002237	response to molecule of bacterial origin	59/1012	224/8380	2.18	2.69e-09	6.38e-08	224
GO:0006959	GO:0006959	humoral immune response	51/1012	181/8380	2.33	2.76e-09	6.49e-08	181
GO:0071356	GO:0071356	cellular response to tumor necrosis factor	45/1012	150/8380	2.48	2.79e-09	6.53e-08	150
GO:1902107	GO:1902107	positive regulation of leukocyte differentiation	34/1012	97/8380	2.90	3.03e-09	7.04e-08	97
GO:0060326	GO:0060326	cell chemotaxis	59/1012	225/8380	2.17	3.23e-09	7.47e-08	225
GO:0034612	GO:0034612	response to tumor necrosis factor	47/1012	161/8380	2.42	3.33e-09	7.64e-08	161
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	40/1012	126/8380	2.63	3.51e-09	8.00e-08	126
GO:0060759	GO:0060759	regulation of response to cytokine stimulus	33/1012	93/8380	2.94	3.62e-09	8.21e-08	93
GO:0050853	GO:0050853	B cell receptor signaling pathway	20/1012	40/8380	4.14	4.64e-09	1.04e-07	40
GO:0019882	GO:0019882	antigen processing and presentation	33/1012	94/8380	2.91	4.95e-09	1.11e-07	94
GO:0007249	GO:0007249	I-kappaB kinase/NF-kappaB signaling	40/1012	128/8380	2.59	5.85e-09	1.30e-07	128
GO:0050727	GO:0050727	regulation of inflammatory response	63/1012	251/8380	2.08	6.12e-09	1.35e-07	251
GO:0046633	GO:0046633	alpha-beta T cell proliferation	16/1012	27/8380	4.91	6.51e-09	1.43e-07	27
GO:0043367	GO:0043367	CD4-positive, alpha-beta T cell differentiation	23/1012	52/8380	3.66	6.65e-09	1.45e-07	52
GO:0036230	GO:0036230	granulocyte activation	65/1012	263/8380	2.05	6.78e-09	1.47e-07	263
GO:0050864	GO:0050864	regulation of B cell activation	28/1012	73/8380	3.18	7.62e-09	1.65e-07	73
GO:0032496	GO:0032496	response to lipopolysaccharide	56/1012	214/8380	2.17	8.88e-09	1.91e-07	214
GO:0032623	GO:0032623	interleukin-2 production	21/1012	45/8380	3.86	9.30e-09	1.99e-07	45
GO:0050857	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	12/1012	16/8380	6.21	1.04e-08	2.20e-07	16
GO:0042119	GO:0042119	neutrophil activation	64/1012	260/8380	2.04	1.05e-08	2.22e-07	260
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	30/1012	83/8380	2.99	1.14e-08	2.37e-07	83
GO:0002700	GO:0002700	regulation of production of molecular mediator of immune response	30/1012	83/8380	2.99	1.14e-08	2.37e-07	83
GO:0001959	GO:0001959	regulation of cytokine-mediated signaling pathway	31/1012	88/8380	2.92	1.32e-08	2.73e-07	88
GO:0046637	GO:0046637	regulation of alpha-beta T cell differentiation	20/1012	42/8380	3.94	1.36e-08	2.81e-07	42
GO:0002707	GO:0002707	negative regulation of lymphocyte mediated immunity	15/1012	25/8380	4.97	1.55e-08	3.18e-07	25
GO:0002711	GO:0002711	positive regulation of T cell mediated immunity	18/1012	35/8380	4.26	1.56e-08	3.19e-07	35
GO:0070664	GO:0070664	negative regulation of leukocyte proliferation	23/1012	54/8380	3.53	1.61e-08	3.26e-07	54
GO:0001916	GO:0001916	positive regulation of T cell mediated cytotoxicity	14/1012	22/8380	5.27	1.61e-08	3.26e-07	22
GO:0002230	GO:0002230	positive regulation of defense response to virus by host	11/1012	14/8380	6.51	1.95e-08	3.90e-07	14
GO:0031295	GO:0031295	T cell costimulation	19/1012	39/8380	4.03	1.96e-08	3.90e-07	39
GO:2000514	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	19/1012	39/8380	4.03	1.96e-08	3.90e-07	39
GO:0002758	GO:0002758	innate immune response-activating signal transduction	40/1012	133/8380	2.49	1.98e-08	3.91e-07	133
GO:0032103	GO:0032103	positive regulation of response to external stimulus	54/1012	208/8380	2.15	2.21e-08	4.35e-07	208
GO:0043299	GO:0043299	leukocyte degranulation	67/1012	283/8380	1.96	2.51e-08	4.92e-07	283
GO:0002444	GO:0002444	myeloid leukocyte mediated immunity	68/1012	290/8380	1.94	2.97e-08	5.77e-07	290
GO:0002717	GO:0002717	positive regulation of natural killer cell mediated immunity	15/1012	26/8380	4.78	3.25e-08	6.30e-07	26
GO:0031294	GO:0031294	lymphocyte costimulation	19/1012	40/8380	3.93	3.32e-08	6.39e-07	40
GO:0002275	GO:0002275	myeloid cell activation involved in immune response	68/1012	291/8380	1.93	3.43e-08	6.57e-07	291
GO:0071887	GO:0071887	leukocyte apoptotic process	26/1012	69/8380	3.12	4.02e-08	7.66e-07	69
GO:0060760	GO:0060760	positive regulation of response to cytokine stimulus	18/1012	37/8380	4.03	4.79e-08	9.09e-07	37
GO:0002292	GO:0002292	T cell differentiation involved in immune response	20/1012	45/8380	3.68	5.87e-08	1.11e-06	45
GO:0002367	GO:0002367	cytokine production involved in immune response	25/1012	66/8380	3.14	6.50e-08	1.22e-06	66
GO:1903708	GO:1903708	positive regulation of hemopoiesis	36/1012	118/8380	2.53	6.74e-08	1.26e-06	118
GO:0002685	GO:0002685	regulation of leukocyte migration	40/1012	139/8380	2.38	7.67e-08	1.43e-06	139
GO:0043122	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	35/1012	114/8380	2.54	8.61e-08	1.59e-06	114
GO:0042590	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	13/1012	21/8380	5.13	8.64e-08	1.59e-06	21
GO:0070227	GO:0070227	lymphocyte apoptotic process	20/1012	46/8380	3.60	9.22e-08	1.69e-06	46
GO:0048002	GO:0048002	antigen processing and presentation of peptide antigen	26/1012	72/8380	2.99	1.10e-07	2.01e-06	72
GO:0002283	GO:0002283	neutrophil activation involved in immune response	60/1012	252/8380	1.97	1.11e-07	2.01e-06	252
GO:0035455	GO:0035455	response to interferon-alpha	10/1012	13/8380	6.37	1.28e-07	2.32e-06	13
GO:0046640	GO:0046640	regulation of alpha-beta T cell proliferation	14/1012	25/8380	4.64	1.58e-07	2.84e-06	25
GO:0043370	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	16/1012	32/8380	4.14	1.66e-07	2.97e-06	32
GO:0043312	GO:0043312	neutrophil degranulation	59/1012	249/8380	1.96	1.70e-07	3.02e-06	249
GO:0090022	GO:0090022	regulation of neutrophil chemotaxis	13/1012	22/8380	4.89	1.88e-07	3.33e-06	22
GO:0002507	GO:0002507	tolerance induction	12/1012	19/8380	5.23	2.02e-07	3.55e-06	19
GO:0032480	GO:0032480	negative regulation of type I interferon production	12/1012	19/8380	5.23	2.02e-07	3.55e-06	19
GO:0050663	GO:0050663	cytokine secretion	41/1012	149/8380	2.28	2.05e-07	3.58e-06	149
GO:0030888	GO:0030888	regulation of B cell proliferation	19/1012	44/8380	3.58	2.21e-07	3.84e-06	44
GO:0001961	GO:0001961	positive regulation of cytokine-mediated signaling pathway	16/1012	33/8380	4.01	2.87e-07	4.93e-06	33
GO:0032655	GO:0032655	regulation of interleukin-12 production	16/1012	33/8380	4.01	2.87e-07	4.93e-06	33
GO:0072676	GO:0072676	lymphocyte migration	28/1012	85/8380	2.73	3.35e-07	5.73e-06	85
GO:2000106	GO:2000106	regulation of leukocyte apoptotic process	23/1012	62/8380	3.07	3.40e-07	5.76e-06	62
GO:0002287	GO:0002287	alpha-beta T cell activation involved in immune response	18/1012	41/8380	3.64	3.41e-07	5.76e-06	41
GO:0002293	GO:0002293	alpha-beta T cell differentiation involved in immune response	18/1012	41/8380	3.64	3.41e-07	5.76e-06	41
GO:0046718	GO:0046718	viral entry into host cell	26/1012	76/8380	2.83	3.80e-07	6.39e-06	76
GO:0050856	GO:0050856	regulation of T cell receptor signaling pathway	13/1012	23/8380	4.68	3.85e-07	6.44e-06	23
GO:0002475	GO:0002475	antigen processing and presentation via MHC class Ib	10/1012	14/8380	5.91	4.01e-07	6.68e-06	14
GO:0045824	GO:0045824	negative regulation of innate immune response	15/1012	30/8380	4.14	4.08e-07	6.75e-06	30
GO:0030260	GO:0030260	entry into host cell	27/1012	81/8380	2.76	4.14e-07	6.75e-06	81
GO:0044409	GO:0044409	entry into host	27/1012	81/8380	2.76	4.14e-07	6.75e-06	81
GO:0051806	GO:0051806	entry into cell of other organism involved in symbiotic interaction	27/1012	81/8380	2.76	4.14e-07	6.75e-06	81
GO:0051828	GO:0051828	entry into other organism involved in symbiotic interaction	27/1012	81/8380	2.76	4.14e-07	6.75e-06	81
GO:0030593	GO:0030593	neutrophil chemotaxis	28/1012	86/8380	2.70	4.40e-07	7.14e-06	86
GO:0002446	GO:0002446	neutrophil mediated immunity	59/1012	256/8380	1.91	4.67e-07	7.55e-06	256
GO:0032102	GO:0032102	negative regulation of response to external stimulus	52/1012	215/8380	2.00	4.69e-07	7.55e-06	215
GO:0032615	GO:0032615	interleukin-12 production	16/1012	34/8380	3.90	4.81e-07	7.71e-06	34
GO:0032663	GO:0032663	regulation of interleukin-2 production	17/1012	38/8380	3.70	5.21e-07	8.31e-06	38
GO:0030595	GO:0030595	leukocyte chemotaxis	44/1012	172/8380	2.12	7.02e-07	1.11e-05	172
GO:0097696	GO:0097696	STAT cascade	27/1012	83/8380	2.69	7.19e-07	1.14e-05	83
GO:0032735	GO:0032735	positive regulation of interleukin-12 production	13/1012	24/8380	4.49	7.47e-07	1.17e-05	24
GO:0045954	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	13/1012	24/8380	4.49	7.47e-07	1.17e-05	24
GO:1902622	GO:1902622	regulation of neutrophil migration	13/1012	24/8380	4.49	7.47e-07	1.17e-05	24
GO:0051701	GO:0051701	interaction with host	31/1012	103/8380	2.49	7.64e-07	1.18e-05	103
GO:1990266	GO:1990266	neutrophil migration	29/1012	93/8380	2.58	7.65e-07	1.18e-05	93
GO:0032653	GO:0032653	regulation of interleukin-10 production	16/1012	35/8380	3.79	7.88e-07	1.22e-05	35
GO:0002418	GO:0002418	immune response to tumor cell	9/1012	12/8380	6.21	8.27e-07	1.27e-05	12
GO:0045066	GO:0045066	regulatory T cell differentiation	12/1012	21/8380	4.73	9.35e-07	1.42e-05	21
GO:0098586	GO:0098586	cellular response to virus	12/1012	21/8380	4.73	9.35e-07	1.42e-05	21
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	32/1012	109/8380	2.43	9.41e-07	1.43e-05	109
GO:0002690	GO:0002690	positive regulation of leukocyte chemotaxis	22/1012	61/8380	2.99	1.07e-06	1.62e-05	61
GO:0090023	GO:0090023	positive regulation of neutrophil chemotaxis	11/1012	18/8380	5.06	1.07e-06	1.62e-05	18
GO:0097529	GO:0097529	myeloid leukocyte migration	41/1012	158/8380	2.15	1.12e-06	1.68e-05	158
GO:0042088	GO:0042088	T-helper 1 type immune response	15/1012	32/8380	3.88	1.18e-06	1.75e-05	32
GO:0032613	GO:0032613	interleukin-10 production	16/1012	36/8380	3.68	1.26e-06	1.87e-05	36
GO:0002294	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	17/1012	40/8380	3.52	1.27e-06	1.87e-05	40
GO:2000107	GO:2000107	negative regulation of leukocyte apoptotic process	17/1012	40/8380	3.52	1.27e-06	1.87e-05	40
GO:0002834	GO:0002834	regulation of response to tumor cell	8/1012	10/8380	6.62	1.59e-06	2.30e-05	10
GO:0002837	GO:0002837	regulation of immune response to tumor cell	8/1012	10/8380	6.62	1.59e-06	2.30e-05	10
GO:0002221	GO:0002221	pattern recognition receptor signaling pathway	29/1012	96/8380	2.50	1.59e-06	2.30e-05	96
GO:0050921	GO:0050921	positive regulation of chemotaxis	29/1012	96/8380	2.50	1.59e-06	2.30e-05	96
GO:1903555	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	29/1012	96/8380	2.50	1.59e-06	2.30e-05	96
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	19/1012	49/8380	3.21	1.63e-06	2.35e-05	49
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	19/1012	49/8380	3.21	1.63e-06	2.35e-05	49
GO:0050920	GO:0050920	regulation of chemotaxis	40/1012	155/8380	2.14	1.77e-06	2.52e-05	155
GO:0050707	GO:0050707	regulation of cytokine secretion	35/1012	128/8380	2.26	1.87e-06	2.66e-05	128
GO:0070231	GO:0070231	T cell apoptotic process	15/1012	33/8380	3.76	1.92e-06	2.72e-05	33
GO:0070228	GO:0070228	regulation of lymphocyte apoptotic process	17/1012	41/8380	3.43	1.92e-06	2.72e-05	41
GO:0071706	GO:0071706	tumor necrosis factor superfamily cytokine production	29/1012	97/8380	2.48	2.01e-06	2.83e-05	97
GO:0002718	GO:0002718	regulation of cytokine production involved in immune response	20/1012	54/8380	3.07	2.04e-06	2.86e-05	54
GO:0007162	GO:0007162	negative regulation of cell adhesion	43/1012	173/8380	2.06	2.15e-06	3.00e-05	173
GO:0019724	GO:0019724	B cell mediated immunity	23/1012	68/8380	2.80	2.23e-06	3.10e-05	68
GO:0036037	GO:0036037	CD8-positive, alpha-beta T cell activation	11/1012	19/8380	4.79	2.27e-06	3.14e-05	19
GO:0046641	GO:0046641	positive regulation of alpha-beta T cell proliferation	11/1012	19/8380	4.79	2.27e-06	3.14e-05	19
GO:0002710	GO:0002710	negative regulation of T cell mediated immunity	9/1012	13/8380	5.73	2.40e-06	3.30e-05	13
GO:0002369	GO:0002369	T cell cytokine production	13/1012	26/8380	4.14	2.46e-06	3.35e-05	26
GO:0032481	GO:0032481	positive regulation of type I interferon production	13/1012	26/8380	4.14	2.46e-06	3.35e-05	26
GO:2000516	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	13/1012	26/8380	4.14	2.46e-06	3.35e-05	26
GO:0002577	GO:0002577	regulation of antigen processing and presentation	10/1012	16/8380	5.18	2.55e-06	3.45e-05	16
GO:0045076	GO:0045076	regulation of interleukin-2 biosynthetic process	10/1012	16/8380	5.18	2.55e-06	3.45e-05	16
GO:0033077	GO:0033077	T cell differentiation in thymus	18/1012	46/8380	3.24	2.63e-06	3.54e-05	46
GO:0097028	GO:0097028	dendritic cell differentiation	14/1012	30/8380	3.86	2.87e-06	3.85e-05	30
GO:0002825	GO:0002825	regulation of T-helper 1 type immune response	12/1012	23/8380	4.32	3.41e-06	4.54e-05	23
GO:0032620	GO:0032620	interleukin-17 production	12/1012	23/8380	4.32	3.41e-06	4.54e-05	23
GO:0006909	GO:0006909	phagocytosis	37/1012	143/8380	2.14	4.02e-06	5.33e-05	143
GO:0043123	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	27/1012	90/8380	2.48	4.19e-06	5.54e-05	90
GO:0007259	GO:0007259	JAK-STAT cascade	25/1012	80/8380	2.59	4.21e-06	5.54e-05	80
GO:0032660	GO:0032660	regulation of interleukin-17 production	11/1012	20/8380	4.55	4.50e-06	5.87e-05	20
GO:0071624	GO:0071624	positive regulation of granulocyte chemotaxis	11/1012	20/8380	4.55	4.50e-06	5.87e-05	20
GO:1902624	GO:1902624	positive regulation of neutrophil migration	11/1012	20/8380	4.55	4.50e-06	5.87e-05	20
GO:0046638	GO:0046638	positive regulation of alpha-beta T cell differentiation	14/1012	31/8380	3.74	4.66e-06	6.05e-05	31
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	52/1012	231/8380	1.86	4.70e-06	6.09e-05	231
GO:0042035	GO:0042035	regulation of cytokine biosynthetic process	22/1012	66/8380	2.76	4.86e-06	6.27e-05	66
GO:0001911	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	8/1012	11/8380	6.02	5.20e-06	6.64e-05	11
GO:0031342	GO:0031342	negative regulation of cell killing	8/1012	11/8380	6.02	5.20e-06	6.64e-05	11
GO:0043011	GO:0043011	myeloid dendritic cell differentiation	8/1012	11/8380	6.02	5.20e-06	6.64e-05	11
GO:0002479	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	10/1012	17/8380	4.87	5.52e-06	7.00e-05	17
GO:0002832	GO:0002832	negative regulation of response to biotic stimulus	10/1012	17/8380	4.87	5.52e-06	7.00e-05	17
GO:0030183	GO:0030183	B cell differentiation	21/1012	62/8380	2.80	5.97e-06	7.55e-05	62
GO:0051090	GO:0051090	regulation of DNA-binding transcription factor activity	48/1012	209/8380	1.90	6.11e-06	7.70e-05	209
GO:0016064	GO:0016064	immunoglobulin mediated immune response	22/1012	67/8380	2.72	6.42e-06	8.06e-05	67
GO:0032680	GO:0032680	regulation of tumor necrosis factor production	27/1012	92/8380	2.43	6.64e-06	8.31e-05	92
GO:0042089	GO:0042089	cytokine biosynthetic process	23/1012	72/8380	2.65	6.71e-06	8.37e-05	72
GO:0002833	GO:0002833	positive regulation of response to biotic stimulus	13/1012	28/8380	3.84	7.03e-06	8.73e-05	28
GO:0071622	GO:0071622	regulation of granulocyte chemotaxis	14/1012	32/8380	3.62	7.37e-06	9.13e-05	32
GO:0032640	GO:0032640	tumor necrosis factor production	27/1012	93/8380	2.40	8.30e-06	1.03e-04	93
GO:0042107	GO:0042107	cytokine metabolic process	23/1012	73/8380	2.61	8.70e-06	1.07e-04	73
GO:0097530	GO:0097530	granulocyte migration	30/1012	109/8380	2.28	8.71e-06	1.07e-04	109
GO:0071621	GO:0071621	granulocyte chemotaxis	28/1012	99/8380	2.34	9.84e-06	1.20e-04	99
GO:0042108	GO:0042108	positive regulation of cytokine biosynthetic process	16/1012	41/8380	3.23	9.87e-06	1.20e-04	41
GO:0033209	GO:0033209	tumor necrosis factor-mediated signaling pathway	22/1012	69/8380	2.64	1.10e-05	1.33e-04	69
GO:0042094	GO:0042094	interleukin-2 biosynthetic process	10/1012	18/8380	4.60	1.11e-05	1.34e-04	18
GO:0070232	GO:0070232	regulation of T cell apoptotic process	13/1012	29/8380	3.71	1.13e-05	1.37e-04	29
GO:0002548	GO:0002548	monocyte chemotaxis	19/1012	55/8380	2.86	1.19e-05	1.44e-04	55
GO:0001776	GO:0001776	leukocyte homeostasis	20/1012	60/8380	2.76	1.30e-05	1.56e-04	60
GO:0045061	GO:0045061	thymic T cell selection	9/1012	15/8380	4.97	1.34e-05	1.60e-04	15
GO:2001185	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	8/1012	12/8380	5.52	1.39e-05	1.66e-04	12
GO:0002224	GO:0002224	toll-like receptor signaling pathway	23/1012	75/8380	2.54	1.43e-05	1.70e-04	75
GO:0043372	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	11/1012	22/8380	4.14	1.50e-05	1.78e-04	22
GO:0042093	GO:0042093	T-helper cell differentiation	15/1012	38/8380	3.27	1.59e-05	1.88e-04	38
GO:0072678	GO:0072678	T cell migration	17/1012	47/8380	3.00	1.71e-05	2.02e-04	47
GO:0002823	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	12/1012	26/8380	3.82	1.72e-05	2.02e-04	26
GO:0048247	GO:0048247	lymphocyte chemotaxis	18/1012	52/8380	2.87	1.96e-05	2.29e-04	52
GO:0002687	GO:0002687	positive regulation of leukocyte migration	26/1012	92/8380	2.34	2.06e-05	2.40e-04	92
GO:0045589	GO:0045589	regulation of regulatory T cell differentiation	10/1012	19/8380	4.36	2.09e-05	2.42e-04	19
GO:0050728	GO:0050728	negative regulation of inflammatory response	25/1012	87/8380	2.38	2.16e-05	2.51e-04	87
GO:0002478	GO:0002478	antigen processing and presentation of exogenous peptide antigen	20/1012	62/8380	2.67	2.26e-05	2.61e-04	62
GO:0051092	GO:0051092	positive regulation of NF-kappaB transcription factor activity	23/1012	77/8380	2.47	2.31e-05	2.66e-04	77
GO:0019884	GO:0019884	antigen processing and presentation of exogenous antigen	21/1012	67/8380	2.60	2.32e-05	2.66e-04	67
GO:0045622	GO:0045622	regulation of T-helper cell differentiation	11/1012	23/8380	3.96	2.56e-05	2.92e-04	23
GO:0046636	GO:0046636	negative regulation of alpha-beta T cell activation	11/1012	23/8380	3.96	2.56e-05	2.92e-04	23
GO:0002702	GO:0002702	positive regulation of production of molecular mediator of immune response	18/1012	53/8380	2.81	2.63e-05	2.99e-04	53
GO:0002360	GO:0002360	T cell lineage commitment	9/1012	16/8380	4.66	2.73e-05	3.07e-04	16
GO:0002827	GO:0002827	positive regulation of T-helper 1 type immune response	9/1012	16/8380	4.66	2.73e-05	3.07e-04	16
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	9/1012	16/8380	4.66	2.73e-05	3.07e-04	16
GO:0072538	GO:0072538	T-helper 17 type immune response	9/1012	16/8380	4.66	2.73e-05	3.07e-04	16
GO:0045055	GO:0045055	regulated exocytosis	85/1012	460/8380	1.53	2.79e-05	3.13e-04	460
GO:0002260	GO:0002260	lymphocyte homeostasis	16/1012	44/8380	3.01	2.80e-05	3.13e-04	44
GO:1903557	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	19/1012	58/8380	2.71	2.83e-05	3.14e-04	58
GO:0043383	GO:0043383	negative T cell selection	7/1012	10/8380	5.80	3.17e-05	3.50e-04	10
GO:0050862	GO:0050862	positive regulation of T cell receptor signaling pathway	7/1012	10/8380	5.80	3.17e-05	3.50e-04	10
GO:0002377	GO:0002377	immunoglobulin production	17/1012	49/8380	2.87	3.21e-05	3.54e-04	49
GO:0050690	GO:0050690	regulation of defense response to virus by virus	8/1012	13/8380	5.10	3.24e-05	3.54e-04	13
GO:0060330	GO:0060330	regulation of response to interferon-gamma	8/1012	13/8380	5.10	3.24e-05	3.54e-04	13
GO:0060334	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	8/1012	13/8380	5.10	3.24e-05	3.54e-04	13
GO:0019722	GO:0019722	calcium-mediated signaling	36/1012	150/8380	1.99	3.25e-05	3.54e-04	150
GO:0050869	GO:0050869	negative regulation of B cell activation	10/1012	20/8380	4.14	3.72e-05	4.05e-04	20
GO:0038093	GO:0038093	Fc receptor signaling pathway	20/1012	64/8380	2.59	3.80e-05	4.12e-04	64
GO:0071674	GO:0071674	mononuclear cell migration	21/1012	69/8380	2.52	3.81e-05	4.12e-04	69
GO:0002820	GO:0002820	negative regulation of adaptive immune response	12/1012	28/8380	3.55	4.30e-05	4.63e-04	28
GO:0002920	GO:0002920	regulation of humoral immune response	18/1012	55/8380	2.71	4.64e-05	4.97e-04	55
GO:0032760	GO:0032760	positive regulation of tumor necrosis factor production	18/1012	55/8380	2.71	4.64e-05	4.97e-04	55
GO:0002347	GO:0002347	response to tumor cell	9/1012	17/8380	4.38	5.19e-05	5.51e-04	17
GO:0035743	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	9/1012	17/8380	4.38	5.19e-05	5.51e-04	17
GO:0046596	GO:0046596	regulation of viral entry into host cell	9/1012	17/8380	4.38	5.19e-05	5.51e-04	17
GO:0050871	GO:0050871	positive regulation of B cell activation	16/1012	46/8380	2.88	5.27e-05	5.59e-04	46
GO:0048872	GO:0048872	homeostasis of number of cells	34/1012	142/8380	1.98	5.62e-05	5.93e-04	142
GO:0002701	GO:0002701	negative regulation of production of molecular mediator of immune response	11/1012	25/8380	3.64	6.72e-05	7.08e-04	25
GO:0002643	GO:0002643	regulation of tolerance induction	8/1012	14/8380	4.73	6.76e-05	7.08e-04	14
GO:0035589	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	8/1012	14/8380	4.73	6.76e-05	7.08e-04	14
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	23/1012	82/8380	2.32	6.94e-05	7.23e-04	82
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	23/1012	82/8380	2.32	6.94e-05	7.23e-04	82
GO:0032740	GO:0032740	positive regulation of interleukin-17 production	7/1012	11/8380	5.27	7.80e-05	8.05e-04	11
GO:0043373	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	7/1012	11/8380	5.27	7.80e-05	8.05e-04	11
GO:0045086	GO:0045086	positive regulation of interleukin-2 biosynthetic process	7/1012	11/8380	5.27	7.80e-05	8.05e-04	11
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	23/1012	83/8380	2.29	8.53e-05	8.78e-04	83
GO:1901623	GO:1901623	regulation of lymphocyte chemotaxis	9/1012	18/8380	4.14	9.26e-05	9.51e-04	18
GO:0032612	GO:0032612	interleukin-1 production	19/1012	63/8380	2.50	1.01e-04	1.04e-03	63
GO:0032733	GO:0032733	positive regulation of interleukin-10 production	10/1012	22/8380	3.76	1.04e-04	1.05e-03	22
GO:0032753	GO:0032753	positive regulation of interleukin-4 production	10/1012	22/8380	3.76	1.04e-04	1.05e-03	22
GO:0070229	GO:0070229	negative regulation of lymphocyte apoptotic process	11/1012	26/8380	3.50	1.04e-04	1.05e-03	26
GO:0051208	GO:0051208	sequestering of calcium ion	23/1012	84/8380	2.27	1.04e-04	1.06e-03	84
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	52/1012	259/8380	1.66	1.26e-04	1.27e-03	259
GO:0006956	GO:0006956	complement activation	17/1012	54/8380	2.61	1.29e-04	1.28e-03	54
GO:0032611	GO:0032611	interleukin-1 beta production	17/1012	54/8380	2.61	1.29e-04	1.28e-03	54
GO:0032652	GO:0032652	regulation of interleukin-1 production	17/1012	54/8380	2.61	1.29e-04	1.28e-03	54
GO:0032607	GO:0032607	interferon-alpha production	8/1012	15/8380	4.42	1.30e-04	1.28e-03	15
GO:0032647	GO:0032647	regulation of interferon-alpha production	8/1012	15/8380	4.42	1.30e-04	1.28e-03	15
GO:0043330	GO:0043330	response to exogenous dsRNA	8/1012	15/8380	4.42	1.30e-04	1.28e-03	15
GO:0072539	GO:0072539	T-helper 17 cell differentiation	8/1012	15/8380	4.42	1.30e-04	1.28e-03	15
GO:0006911	GO:0006911	phagocytosis, engulfment	12/1012	31/8380	3.21	1.41e-04	1.40e-03	31
GO:0002573	GO:0002573	myeloid leukocyte differentiation	31/1012	131/8380	1.96	1.49e-04	1.47e-03	131
GO:0070233	GO:0070233	negative regulation of T cell apoptotic process	9/1012	19/8380	3.92	1.57e-04	1.55e-03	19
GO:0030099	GO:0030099	myeloid cell differentiation	46/1012	223/8380	1.71	1.59e-04	1.56e-03	223
GO:0035588	GO:0035588	G protein-coupled purinergic receptor signaling pathway	10/1012	23/8380	3.60	1.64e-04	1.60e-03	23
GO:0050764	GO:0050764	regulation of phagocytosis	17/1012	55/8380	2.56	1.67e-04	1.63e-03	55
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	7/1012	12/8380	4.83	1.68e-04	1.63e-03	12
GO:0018108	GO:0018108	peptidyl-tyrosine phosphorylation	50/1012	249/8380	1.66	1.69e-04	1.63e-03	249
GO:0018212	GO:0018212	peptidyl-tyrosine modification	50/1012	249/8380	1.66	1.69e-04	1.63e-03	249
GO:0051091	GO:0051091	positive regulation of DNA-binding transcription factor activity	31/1012	132/8380	1.94	1.72e-04	1.66e-03	132
GO:0034121	GO:0034121	regulation of toll-like receptor signaling pathway	14/1012	41/8380	2.83	1.93e-04	1.86e-03	41
GO:0002637	GO:0002637	regulation of immunoglobulin production	12/1012	32/8380	3.11	2.01e-04	1.93e-03	32
GO:0032651	GO:0032651	regulation of interleukin-1 beta production	15/1012	46/8380	2.70	2.06e-04	1.98e-03	46
GO:0050855	GO:0050855	regulation of B cell receptor signaling pathway	8/1012	16/8380	4.14	2.32e-04	2.21e-03	16
GO:0072507	GO:0072507	divalent inorganic cation homeostasis	65/1012	351/8380	1.53	2.32e-04	2.21e-03	351
GO:0002724	GO:0002724	regulation of T cell cytokine production	9/1012	20/8380	3.73	2.55e-04	2.42e-03	20
GO:0032743	GO:0032743	positive regulation of interleukin-2 production	9/1012	20/8380	3.73	2.55e-04	2.42e-03	20
GO:0032814	GO:0032814	regulation of natural killer cell activation	9/1012	20/8380	3.73	2.55e-04	2.42e-03	20
GO:0051345	GO:0051345	positive regulation of hydrolase activity	70/1012	386/8380	1.50	2.57e-04	2.43e-03	386
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	18/1012	62/8380	2.40	2.61e-04	2.46e-03	62
GO:0042742	GO:0042742	defense response to bacterium	33/1012	147/8380	1.86	2.66e-04	2.50e-03	147
GO:0006874	GO:0006874	cellular calcium ion homeostasis	59/1012	313/8380	1.56	2.77e-04	2.59e-03	313
GO:0099024	GO:0099024	plasma membrane invagination	12/1012	33/8380	3.01	2.82e-04	2.63e-03	33
GO:0031663	GO:0031663	lipopolysaccharide-mediated signaling pathway	13/1012	38/8380	2.83	3.19e-04	2.96e-03	38
GO:0042130	GO:0042130	negative regulation of T cell proliferation	13/1012	38/8380	2.83	3.19e-04	2.96e-03	38
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	7/1012	13/8380	4.46	3.25e-04	3.02e-03	13
GO:0002712	GO:0002712	regulation of B cell mediated immunity	11/1012	29/8380	3.14	3.30e-04	3.04e-03	29
GO:0002889	GO:0002889	regulation of immunoglobulin mediated immune response	11/1012	29/8380	3.14	3.30e-04	3.04e-03	29
GO:0043300	GO:0043300	regulation of leukocyte degranulation	11/1012	29/8380	3.14	3.30e-04	3.04e-03	29
GO:0002673	GO:0002673	regulation of acute inflammatory response	20/1012	74/8380	2.24	3.50e-04	3.21e-03	74
GO:0072503	GO:0072503	cellular divalent inorganic cation homeostasis	62/1012	336/8380	1.53	3.56e-04	3.26e-03	336
GO:0032673	GO:0032673	regulation of interleukin-4 production	10/1012	25/8380	3.31	3.73e-04	3.40e-03	25
GO:0045581	GO:0045581	negative regulation of T cell differentiation	10/1012	25/8380	3.31	3.73e-04	3.40e-03	25
GO:0010324	GO:0010324	membrane invagination	12/1012	34/8380	2.92	3.89e-04	3.53e-03	34
GO:0002407	GO:0002407	dendritic cell chemotaxis	8/1012	17/8380	3.90	3.92e-04	3.55e-03	17
GO:0002753	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	9/1012	21/8380	3.55	3.99e-04	3.60e-03	21
GO:0055074	GO:0055074	calcium ion homeostasis	60/1012	324/8380	1.53	4.01e-04	3.61e-03	324
GO:0002295	GO:0002295	T-helper cell lineage commitment	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0002430	GO:0002430	complement receptor mediated signaling pathway	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0002517	GO:0002517	T cell tolerance induction	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0010819	GO:0010819	regulation of T cell chemotaxis	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0033631	GO:0033631	cell-cell adhesion mediated by integrin	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0043374	GO:0043374	CD8-positive, alpha-beta T cell differentiation	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0045591	GO:0045591	positive regulation of regulatory T cell differentiation	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:0046597	GO:0046597	negative regulation of viral entry into host cell	6/1012	10/8380	4.97	4.17e-04	3.68e-03	10
GO:1904892	GO:1904892	regulation of STAT cascade	20/1012	75/8380	2.21	4.24e-04	3.71e-03	75
GO:1904894	GO:1904894	positive regulation of STAT cascade	17/1012	59/8380	2.39	4.24e-04	3.71e-03	59
GO:0043065	GO:0043065	positive regulation of apoptotic process	59/1012	318/8380	1.54	4.25e-04	3.71e-03	318
GO:0002431	GO:0002431	Fc receptor mediated stimulatory signaling pathway	13/1012	39/8380	2.76	4.26e-04	3.71e-03	39
GO:0030449	GO:0030449	regulation of complement activation	13/1012	39/8380	2.76	4.26e-04	3.71e-03	39
GO:0032633	GO:0032633	interleukin-4 production	11/1012	30/8380	3.04	4.65e-04	4.04e-03	30
GO:0050706	GO:0050706	regulation of interleukin-1 beta secretion	11/1012	30/8380	3.04	4.65e-04	4.04e-03	30
GO:0070555	GO:0070555	response to interleukin-1	24/1012	98/8380	2.03	4.72e-04	4.09e-03	98
GO:0043068	GO:0043068	positive regulation of programmed cell death	59/1012	320/8380	1.53	5.02e-04	4.34e-03	320
GO:0002526	GO:0002526	acute inflammatory response	27/1012	116/8380	1.93	5.15e-04	4.44e-03	116
GO:0002886	GO:0002886	regulation of myeloid leukocyte mediated immunity	12/1012	35/8380	2.84	5.27e-04	4.52e-03	35
GO:0050702	GO:0050702	interleukin-1 beta secretion	12/1012	35/8380	2.84	5.27e-04	4.52e-03	35
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	16/1012	55/8380	2.41	5.52e-04	4.73e-03	55
GO:2000257	GO:2000257	regulation of protein activation cascade	13/1012	40/8380	2.69	5.62e-04	4.80e-03	40
GO:0006471	GO:0006471	protein ADP-ribosylation	7/1012	14/8380	4.14	5.83e-04	4.96e-03	14
GO:0045063	GO:0045063	T-helper 1 cell differentiation	7/1012	14/8380	4.14	5.83e-04	4.96e-03	14
GO:0002719	GO:0002719	negative regulation of cytokine production involved in immune response	8/1012	18/8380	3.68	6.31e-04	5.30e-03	18
GO:0032703	GO:0032703	negative regulation of interleukin-2 production	8/1012	18/8380	3.68	6.31e-04	5.30e-03	18
GO:0035590	GO:0035590	purinergic nucleotide receptor signaling pathway	8/1012	18/8380	3.68	6.31e-04	5.30e-03	18
GO:0043331	GO:0043331	response to dsRNA	8/1012	18/8380	3.68	6.31e-04	5.30e-03	18
GO:0030890	GO:0030890	positive regulation of B cell proliferation	11/1012	31/8380	2.94	6.43e-04	5.38e-03	31
GO:0032088	GO:0032088	negative regulation of NF-kappaB transcription factor activity	11/1012	31/8380	2.94	6.43e-04	5.38e-03	31
GO:0071347	GO:0071347	cellular response to interleukin-1	21/1012	83/8380	2.10	6.61e-04	5.52e-03	83
GO:0060402	GO:0060402	calcium ion transport into cytosol	25/1012	106/8380	1.95	6.65e-04	5.54e-03	106
GO:0050715	GO:0050715	positive regulation of cytokine secretion	22/1012	89/8380	2.05	7.00e-04	5.82e-03	89
GO:0002686	GO:0002686	negative regulation of leukocyte migration	12/1012	36/8380	2.76	7.05e-04	5.85e-03	36
GO:0050766	GO:0050766	positive regulation of phagocytosis	13/1012	41/8380	2.63	7.33e-04	6.07e-03	41
GO:0035587	GO:0035587	purinergic receptor signaling pathway	10/1012	27/8380	3.07	7.67e-04	6.34e-03	27
GO:0060401	GO:0060401	cytosolic calcium ion transport	25/1012	107/8380	1.93	7.70e-04	6.35e-03	107
GO:0001771	GO:0001771	immunological synapse formation	6/1012	11/8380	4.52	8.24e-04	6.71e-03	11
GO:0032727	GO:0032727	positive regulation of interferon-alpha production	6/1012	11/8380	4.52	8.24e-04	6.71e-03	11
GO:0032816	GO:0032816	positive regulation of natural killer cell activation	6/1012	11/8380	4.52	8.24e-04	6.71e-03	11
GO:0039694	GO:0039694	viral RNA genome replication	6/1012	11/8380	4.52	8.24e-04	6.71e-03	11
GO:0002720	GO:0002720	positive regulation of cytokine production involved in immune response	11/1012	32/8380	2.85	8.74e-04	7.11e-03	32
GO:0097190	GO:0097190	apoptotic signaling pathway	53/1012	287/8380	1.53	9.18e-04	7.45e-03	287
GO:0010524	GO:0010524	positive regulation of calcium ion transport into cytosol	12/1012	37/8380	2.69	9.30e-04	7.53e-03	37
GO:0032692	GO:0032692	negative regulation of interleukin-1 production	8/1012	19/8380	3.49	9.75e-04	7.77e-03	19
GO:0036336	GO:0036336	dendritic cell migration	8/1012	19/8380	3.49	9.75e-04	7.77e-03	19
GO:0045577	GO:0045577	regulation of B cell differentiation	8/1012	19/8380	3.49	9.75e-04	7.77e-03	19
GO:0045920	GO:0045920	negative regulation of exocytosis	8/1012	19/8380	3.49	9.75e-04	7.77e-03	19
GO:0090025	GO:0090025	regulation of monocyte chemotaxis	8/1012	19/8380	3.49	9.75e-04	7.77e-03	19
GO:0001779	GO:0001779	natural killer cell differentiation	7/1012	15/8380	3.86	9.80e-04	7.77e-03	15
GO:0032691	GO:0032691	negative regulation of interleukin-1 beta production	7/1012	15/8380	3.86	9.80e-04	7.77e-03	15
GO:0048535	GO:0048535	lymph node development	7/1012	15/8380	3.86	9.80e-04	7.77e-03	15
GO:1903306	GO:1903306	negative regulation of regulated secretory pathway	7/1012	15/8380	3.86	9.80e-04	7.77e-03	15
GO:2000515	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	7/1012	15/8380	3.86	9.80e-04	7.77e-03	15
GO:0002437	GO:0002437	inflammatory response to antigenic stimulus	10/1012	28/8380	2.96	1.07e-03	8.40e-03	28
GO:0019835	GO:0019835	cytolysis	10/1012	28/8380	2.96	1.07e-03	8.40e-03	28
GO:0051281	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	10/1012	28/8380	2.96	1.07e-03	8.40e-03	28
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	23/1012	98/8380	1.94	1.15e-03	9.05e-03	98
GO:0050922	GO:0050922	negative regulation of chemotaxis	14/1012	48/8380	2.42	1.17e-03	9.19e-03	48
GO:0002828	GO:0002828	regulation of type 2 immune response	9/1012	24/8380	3.11	1.27e-03	9.89e-03	24
GO:0043029	GO:0043029	T cell homeostasis	9/1012	24/8380	3.11	1.27e-03	9.89e-03	24
GO:0050830	GO:0050830	defense response to Gram-positive bacterium	15/1012	54/8380	2.30	1.38e-03	1.07e-02	54
GO:0050798	GO:0050798	activated T cell proliferation	10/1012	29/8380	2.86	1.45e-03	1.11e-02	29
GO:0002714	GO:0002714	positive regulation of B cell mediated immunity	8/1012	20/8380	3.31	1.45e-03	1.11e-02	20
GO:0002891	GO:0002891	positive regulation of immunoglobulin mediated immune response	8/1012	20/8380	3.31	1.45e-03	1.11e-02	20
GO:0010818	GO:0010818	T cell chemotaxis	8/1012	20/8380	3.31	1.45e-03	1.11e-02	20
GO:0032608	GO:0032608	interferon-beta production	8/1012	20/8380	3.31	1.45e-03	1.11e-02	20
GO:0032648	GO:0032648	regulation of interferon-beta production	8/1012	20/8380	3.31	1.45e-03	1.11e-02	20
GO:0060338	GO:0060338	regulation of type I interferon-mediated signaling pathway	6/1012	12/8380	4.14	1.48e-03	1.13e-02	12
GO:0045807	GO:0045807	positive regulation of endocytosis	21/1012	88/8380	1.98	1.49e-03	1.13e-02	88
GO:0050704	GO:0050704	regulation of interleukin-1 secretion	11/1012	34/8380	2.68	1.54e-03	1.17e-02	34
GO:0002544	GO:0002544	chronic inflammatory response	7/1012	16/8380	3.62	1.56e-03	1.18e-02	16
GO:0002689	GO:0002689	negative regulation of leukocyte chemotaxis	7/1012	16/8380	3.62	1.56e-03	1.18e-02	16
GO:0002861	GO:0002861	regulation of inflammatory response to antigenic stimulus	7/1012	16/8380	3.62	1.56e-03	1.18e-02	16
GO:0033622	GO:0033622	integrin activation	7/1012	16/8380	3.62	1.56e-03	1.18e-02	16
GO:0050858	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	7/1012	16/8380	3.62	1.56e-03	1.18e-02	16
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	15/1012	55/8380	2.26	1.69e-03	1.27e-02	55
GO:0046425	GO:0046425	regulation of JAK-STAT cascade	18/1012	72/8380	2.07	1.81e-03	1.36e-02	72
GO:0007260	GO:0007260	tyrosine phosphorylation of STAT protein	14/1012	50/8380	2.32	1.81e-03	1.36e-02	50
GO:0045637	GO:0045637	regulation of myeloid cell differentiation	29/1012	138/8380	1.74	1.84e-03	1.38e-02	138
GO:0038095	GO:0038095	Fc-epsilon receptor signaling pathway	10/1012	30/8380	2.76	1.95e-03	1.45e-02	30
GO:0043550	GO:0043550	regulation of lipid kinase activity	12/1012	40/8380	2.48	1.99e-03	1.48e-02	40
GO:0050701	GO:0050701	interleukin-1 secretion	12/1012	40/8380	2.48	1.99e-03	1.48e-02	40
GO:0002455	GO:0002455	humoral immune response mediated by circulating immunoglobulin	11/1012	35/8380	2.60	2.01e-03	1.49e-02	35
GO:2000406	GO:2000406	positive regulation of T cell migration	8/1012	21/8380	3.15	2.10e-03	1.55e-02	21
GO:0007229	GO:0007229	integrin-mediated signaling pathway	18/1012	73/8380	2.04	2.14e-03	1.57e-02	73
GO:0031664	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	7/1012	17/8380	3.41	2.38e-03	1.75e-02	17
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	17/1012	68/8380	2.07	2.40e-03	1.76e-02	68
GO:0042092	GO:0042092	type 2 immune response	9/1012	26/8380	2.87	2.43e-03	1.77e-02	26
GO:0046006	GO:0046006	regulation of activated T cell proliferation	9/1012	26/8380	2.87	2.43e-03	1.77e-02	26
GO:0032604	GO:0032604	granulocyte macrophage colony-stimulating factor production	6/1012	13/8380	3.82	2.47e-03	1.78e-02	13
GO:0032728	GO:0032728	positive regulation of interferon-beta production	6/1012	13/8380	3.82	2.47e-03	1.78e-02	13
GO:0051767	GO:0051767	nitric-oxide synthase biosynthetic process	6/1012	13/8380	3.82	2.47e-03	1.78e-02	13
GO:0051769	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	6/1012	13/8380	3.82	2.47e-03	1.78e-02	13
GO:0090026	GO:0090026	positive regulation of monocyte chemotaxis	6/1012	13/8380	3.82	2.47e-03	1.78e-02	13
GO:0042116	GO:0042116	macrophage activation	15/1012	57/8380	2.18	2.48e-03	1.78e-02	57
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	15/1012	57/8380	2.18	2.48e-03	1.78e-02	57
GO:0002220	GO:0002220	innate immune response activating cell surface receptor signaling pathway	12/1012	41/8380	2.42	2.51e-03	1.80e-02	41
GO:0045620	GO:0045620	negative regulation of lymphocyte differentiation	10/1012	31/8380	2.67	2.57e-03	1.84e-02	31
GO:0043551	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	11/1012	36/8380	2.53	2.58e-03	1.84e-02	36
GO:0046456	GO:0046456	icosanoid biosynthetic process	11/1012	36/8380	2.53	2.58e-03	1.84e-02	36
GO:0033627	GO:0033627	cell adhesion mediated by integrin	14/1012	52/8380	2.23	2.71e-03	1.93e-02	52
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	32/1012	161/8380	1.65	2.83e-03	2.01e-02	161
GO:2000116	GO:2000116	regulation of cysteine-type endopeptidase activity	26/1012	123/8380	1.75	2.84e-03	2.02e-02	123
GO:0007202	GO:0007202	activation of phospholipase C activity	8/1012	22/8380	3.01	2.96e-03	2.08e-02	22
GO:0044764	GO:0044764	multi-organism cellular process	8/1012	22/8380	3.01	2.96e-03	2.08e-02	22
GO:0098760	GO:0098760	response to interleukin-7	8/1012	22/8380	3.01	2.96e-03	2.08e-02	22
GO:0098761	GO:0098761	cellular response to interleukin-7	8/1012	22/8380	3.01	2.96e-03	2.08e-02	22
GO:2000401	GO:2000401	regulation of lymphocyte migration	12/1012	42/8380	2.37	3.14e-03	2.20e-02	42
GO:0001774	GO:0001774	microglial cell activation	9/1012	27/8380	2.76	3.26e-03	2.27e-02	27
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	9/1012	27/8380	2.76	3.26e-03	2.27e-02	27
GO:2000403	GO:2000403	positive regulation of lymphocyte migration	9/1012	27/8380	2.76	3.26e-03	2.27e-02	27
GO:1905517	GO:1905517	macrophage migration	11/1012	37/8380	2.46	3.28e-03	2.29e-02	37
GO:0072376	GO:0072376	protein activation cascade	17/1012	70/8380	2.01	3.33e-03	2.32e-02	70
GO:0071675	GO:0071675	regulation of mononuclear cell migration	10/1012	32/8380	2.59	3.34e-03	2.32e-02	32
GO:0001516	GO:0001516	prostaglandin biosynthetic process	7/1012	18/8380	3.22	3.50e-03	2.41e-02	18
GO:0046135	GO:0046135	pyrimidine nucleoside catabolic process	7/1012	18/8380	3.22	3.50e-03	2.41e-02	18
GO:0046457	GO:0046457	prostanoid biosynthetic process	7/1012	18/8380	3.22	3.50e-03	2.41e-02	18
GO:0071354	GO:0071354	cellular response to interleukin-6	7/1012	18/8380	3.22	3.50e-03	2.41e-02	18
GO:0030100	GO:0030100	regulation of endocytosis	29/1012	144/8380	1.67	3.58e-03	2.46e-02	144
GO:0034103	GO:0034103	regulation of tissue remodeling	13/1012	48/8380	2.24	3.60e-03	2.47e-02	48
GO:1902106	GO:1902106	negative regulation of leukocyte differentiation	16/1012	65/8380	2.04	3.76e-03	2.56e-02	65
GO:0032069	GO:0032069	regulation of nuclease activity	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0032494	GO:0032494	response to peptidoglycan	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0032700	GO:0032700	negative regulation of interleukin-17 production	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0033033	GO:0033033	negative regulation of myeloid cell apoptotic process	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0033089	GO:0033089	positive regulation of T cell differentiation in thymus	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0035747	GO:0035747	natural killer cell chemotaxis	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0042976	GO:0042976	activation of Janus kinase activity	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0070230	GO:0070230	positive regulation of lymphocyte apoptotic process	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0080111	GO:0080111	DNA demethylation	5/1012	10/8380	4.14	3.80e-03	2.56e-02	10
GO:0042454	GO:0042454	ribonucleoside catabolic process	6/1012	14/8380	3.55	3.88e-03	2.60e-02	14
GO:0140131	GO:0140131	positive regulation of lymphocyte chemotaxis	6/1012	14/8380	3.55	3.88e-03	2.60e-02	14
GO:1901224	GO:1901224	positive regulation of NIK/NF-kappaB signaling	12/1012	43/8380	2.31	3.88e-03	2.60e-02	43
GO:0043433	GO:0043433	negative regulation of DNA-binding transcription factor activity	18/1012	77/8380	1.94	3.99e-03	2.67e-02	77
GO:0009164	GO:0009164	nucleoside catabolic process	8/1012	23/8380	2.88	4.07e-03	2.71e-02	23
GO:0002312	GO:0002312	B cell activation involved in immune response	11/1012	38/8380	2.40	4.13e-03	2.74e-02	38
GO:0038094	GO:0038094	Fc-gamma receptor signaling pathway	11/1012	38/8380	2.40	4.13e-03	2.74e-02	38
GO:0097191	GO:0097191	extrinsic apoptotic signaling pathway	25/1012	120/8380	1.73	4.15e-03	2.75e-02	120
GO:0061900	GO:0061900	glial cell activation	10/1012	33/8380	2.51	4.28e-03	2.84e-02	33
GO:0038083	GO:0038083	peptidyl-tyrosine autophosphorylation	9/1012	28/8380	2.66	4.29e-03	2.84e-02	28
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	13/1012	49/8380	2.20	4.37e-03	2.88e-02	49
GO:0006919	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	12/1012	44/8380	2.26	4.77e-03	3.14e-02	44
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	27/1012	134/8380	1.67	4.80e-03	3.15e-02	134
GO:0070671	GO:0070671	response to interleukin-12	7/1012	19/8380	3.05	4.97e-03	3.26e-02	19
GO:0010517	GO:0010517	regulation of phospholipase activity	13/1012	50/8380	2.15	5.26e-03	3.43e-02	50
GO:0034122	GO:0034122	negative regulation of toll-like receptor signaling pathway	8/1012	24/8380	2.76	5.47e-03	3.53e-02	24
GO:0034142	GO:0034142	toll-like receptor 4 signaling pathway	8/1012	24/8380	2.76	5.47e-03	3.53e-02	24
GO:0072677	GO:0072677	eosinophil migration	8/1012	24/8380	2.76	5.47e-03	3.53e-02	24
GO:0034656	GO:0034656	nucleobase-containing small molecule catabolic process	9/1012	29/8380	2.57	5.57e-03	3.59e-02	29
GO:2000404	GO:2000404	regulation of T cell migration	9/1012	29/8380	2.57	5.57e-03	3.59e-02	29
GO:0032656	GO:0032656	regulation of interleukin-13 production	6/1012	15/8380	3.31	5.82e-03	3.73e-02	15
GO:0045624	GO:0045624	positive regulation of T-helper cell differentiation	6/1012	15/8380	3.31	5.82e-03	3.73e-02	15
GO:0061025	GO:0061025	membrane fusion	15/1012	62/8380	2.00	5.88e-03	3.76e-02	62
GO:0043902	GO:0043902	positive regulation of multi-organism process	17/1012	74/8380	1.90	6.11e-03	3.89e-02	74
GO:2001056	GO:2001056	positive regulation of cysteine-type endopeptidase activity	17/1012	74/8380	1.90	6.11e-03	3.89e-02	74
GO:0001783	GO:0001783	B cell apoptotic process	5/1012	11/8380	3.76	6.28e-03	3.97e-02	11
GO:0016553	GO:0016553	base conversion or substitution editing	5/1012	11/8380	3.76	6.28e-03	3.97e-02	11
GO:0032823	GO:0032823	regulation of natural killer cell differentiation	5/1012	11/8380	3.76	6.28e-03	3.97e-02	11
GO:0050860	GO:0050860	negative regulation of T cell receptor signaling pathway	5/1012	11/8380	3.76	6.28e-03	3.97e-02	11
GO:0150076	GO:0150076	neuroinflammatory response	11/1012	40/8380	2.28	6.33e-03	4.00e-02	40
GO:0002433	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	10/1012	35/8380	2.37	6.79e-03	4.28e-02	35
GO:0038096	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	10/1012	35/8380	2.37	6.79e-03	4.28e-02	35
GO:0001782	GO:0001782	B cell homeostasis	7/1012	20/8380	2.90	6.86e-03	4.30e-02	20
GO:0048245	GO:0048245	eosinophil chemotaxis	7/1012	20/8380	2.90	6.86e-03	4.30e-02	20
GO:0071353	GO:0071353	cellular response to interleukin-4	7/1012	20/8380	2.90	6.86e-03	4.30e-02	20
GO:0060191	GO:0060191	regulation of lipase activity	15/1012	63/8380	1.97	6.87e-03	4.30e-02	63
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	12/1012	46/8380	2.16	7.01e-03	4.37e-02	46
GO:0060193	GO:0060193	positive regulation of lipase activity	12/1012	46/8380	2.16	7.01e-03	4.37e-02	46
GO:0002761	GO:0002761	regulation of myeloid leukocyte differentiation	17/1012	75/8380	1.88	7.03e-03	4.38e-02	75
GO:0006958	GO:0006958	complement activation, classical pathway	8/1012	25/8380	2.65	7.20e-03	4.47e-02	25
GO:0010518	GO:0010518	positive regulation of phospholipase activity	11/1012	41/8380	2.22	7.73e-03	4.78e-02	41
GO:1903556	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	11/1012	41/8380	2.22	7.73e-03	4.78e-02	41
GO:0010950	GO:0010950	positive regulation of endopeptidase activity	19/1012	88/8380	1.79	7.85e-03	4.84e-02	88
GO:0070613	GO:0070613	regulation of protein processing	17/1012	76/8380	1.85	8.07e-03	4.97e-02	76

Factor 20 : 324 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001944	GO:0001944	vasculature development	160/1494	465/8380	1.93	7.14e-19	2.29e-15	465
GO:0072358	GO:0072358	cardiovascular system development	161/1494	471/8380	1.92	1.14e-18	2.29e-15	471
GO:0001525	GO:0001525	angiogenesis	127/1494	342/8380	2.08	3.71e-18	4.97e-15	342
GO:0001568	GO:0001568	blood vessel development	153/1494	448/8380	1.92	9.98e-18	1.00e-14	448
GO:0048514	GO:0048514	blood vessel morphogenesis	140/1494	404/8380	1.94	6.85e-17	5.50e-14	404
GO:0001935	GO:0001935	endothelial cell proliferation	48/1494	94/8380	2.86	1.81e-13	1.21e-10	94
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	44/1494	83/8380	2.97	3.34e-13	1.92e-10	83
GO:1901342	GO:1901342	regulation of vasculature development	80/1494	214/8380	2.10	5.17e-12	2.32e-09	214
GO:0030335	GO:0030335	positive regulation of cell migration	107/1494	320/8380	1.88	5.19e-12	2.32e-09	320
GO:0043062	GO:0043062	extracellular structure organization	107/1494	326/8380	1.84	1.90e-11	7.62e-09	326
GO:0030198	GO:0030198	extracellular matrix organization	98/1494	290/8380	1.90	2.14e-11	7.81e-09	290
GO:0040017	GO:0040017	positive regulation of locomotion	112/1494	349/8380	1.80	3.09e-11	1.04e-08	349
GO:2000147	GO:2000147	positive regulation of cell motility	108/1494	333/8380	1.82	3.47e-11	1.07e-08	333
GO:0001667	GO:0001667	ameboidal-type cell migration	84/1494	239/8380	1.97	6.40e-11	1.84e-08	239
GO:0006897	GO:0006897	endocytosis	122/1494	396/8380	1.73	7.97e-11	2.13e-08	396
GO:0051272	GO:0051272	positive regulation of cellular component movement	109/1494	344/8380	1.78	1.36e-10	3.42e-08	344
GO:0045765	GO:0045765	regulation of angiogenesis	70/1494	191/8380	2.06	3.18e-10	7.52e-08	191
GO:0003158	GO:0003158	endothelium development	36/1494	73/8380	2.77	6.88e-10	1.54e-07	73
GO:0098657	GO:0098657	import into cell	139/1494	485/8380	1.61	9.74e-10	2.04e-07	485
GO:0043542	GO:0043542	endothelial cell migration	50/1494	121/8380	2.32	1.01e-09	2.04e-07	121
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	23/1494	37/8380	3.49	2.39e-09	4.58e-07	37
GO:0070848	GO:0070848	response to growth factor	120/1494	410/8380	1.64	3.82e-09	6.97e-07	410
GO:0002040	GO:0002040	sprouting angiogenesis	36/1494	77/8380	2.62	4.38e-09	7.64e-07	77
GO:0001938	GO:0001938	positive regulation of endothelial cell proliferation	31/1494	62/8380	2.80	6.92e-09	1.16e-06	62
GO:0090130	GO:0090130	tissue migration	63/1494	176/8380	2.01	7.24e-09	1.16e-06	176
GO:0050900	GO:0050900	leukocyte migration	98/1494	319/8380	1.72	7.48e-09	1.16e-06	319
GO:0038084	GO:0038084	vascular endothelial growth factor signaling pathway	18/1494	26/8380	3.88	1.10e-08	1.62e-06	26
GO:0045446	GO:0045446	endothelial cell differentiation	31/1494	63/8380	2.76	1.13e-08	1.62e-06	63
GO:0071363	GO:0071363	cellular response to growth factor stimulus	114/1494	391/8380	1.64	1.22e-08	1.69e-06	391
GO:0010631	GO:0010631	epithelial cell migration	60/1494	169/8380	1.99	2.35e-08	3.14e-06	169
GO:0042330	GO:0042330	taxis	130/1494	467/8380	1.56	2.51e-08	3.25e-06	467
GO:0090132	GO:0090132	epithelium migration	60/1494	170/8380	1.98	3.01e-08	3.77e-06	170
GO:0006898	GO:0006898	receptor-mediated endocytosis	64/1494	186/8380	1.93	3.20e-08	3.89e-06	186
GO:0006935	GO:0006935	chemotaxis	129/1494	466/8380	1.55	4.09e-08	4.83e-06	466
GO:0048762	GO:0048762	mesenchymal cell differentiation	52/1494	143/8380	2.04	8.28e-08	9.50e-06	143
GO:0010594	GO:0010594	regulation of endothelial cell migration	37/1494	90/8380	2.31	1.78e-07	1.98e-05	90
GO:1904018	GO:1904018	positive regulation of vasculature development	46/1494	124/8380	2.08	2.35e-07	2.55e-05	124
GO:0060485	GO:0060485	mesenchyme development	62/1494	187/8380	1.86	2.42e-07	2.55e-05	187
GO:0050678	GO:0050678	regulation of epithelial cell proliferation	70/1494	220/8380	1.78	2.49e-07	2.57e-05	220
GO:0060326	GO:0060326	cell chemotaxis	71/1494	225/8380	1.77	2.93e-07	2.94e-05	225
GO:0019932	GO:0019932	second-messenger-mediated signaling	93/1494	320/8380	1.63	3.33e-07	3.26e-05	320
GO:0050673	GO:0050673	epithelial cell proliferation	78/1494	256/8380	1.71	3.84e-07	3.67e-05	256
GO:0043534	GO:0043534	blood vessel endothelial cell migration	30/1494	68/8380	2.47	4.17e-07	3.90e-05	68
GO:0090066	GO:0090066	regulation of anatomical structure size	88/1494	301/8380	1.64	5.23e-07	4.58e-05	301
GO:0001570	GO:0001570	vasculogenesis	25/1494	52/8380	2.70	5.25e-07	4.58e-05	52
GO:0032835	GO:0032835	glomerulus development	25/1494	52/8380	2.70	5.25e-07	4.58e-05	52
GO:0010632	GO:0010632	regulation of epithelial cell migration	46/1494	128/8380	2.02	6.80e-07	5.81e-05	128
GO:0007169	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	108/1494	395/8380	1.53	1.06e-06	8.86e-05	395
GO:0050919	GO:0050919	negative chemotaxis	19/1494	35/8380	3.04	1.17e-06	9.59e-05	35
GO:0050920	GO:0050920	regulation of chemotaxis	52/1494	155/8380	1.88	1.50e-06	1.21e-04	155
GO:0048844	GO:0048844	artery morphogenesis	23/1494	48/8380	2.69	1.61e-06	1.26e-04	48
GO:0050679	GO:0050679	positive regulation of epithelial cell proliferation	47/1494	136/8380	1.94	1.87e-06	1.41e-04	136
GO:0008360	GO:0008360	regulation of cell shape	36/1494	94/8380	2.15	1.99e-06	1.48e-04	94
GO:0097529	GO:0097529	myeloid leukocyte migration	52/1494	158/8380	1.85	2.88e-06	2.10e-04	158
GO:0072001	GO:0072001	renal system development	67/1494	221/8380	1.70	3.09e-06	2.21e-04	221
GO:0090287	GO:0090287	regulation of cellular response to growth factor stimulus	54/1494	167/8380	1.81	3.41e-06	2.40e-04	167
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	23/1494	50/8380	2.58	3.90e-06	2.70e-04	50
GO:0003013	GO:0003013	circulatory system process	98/1494	360/8380	1.53	4.17e-06	2.83e-04	360
GO:0031623	GO:0031623	receptor internalization	26/1494	61/8380	2.39	5.37e-06	3.59e-04	61
GO:0003018	GO:0003018	vascular process in circulatory system	41/1494	117/8380	1.97	5.65e-06	3.72e-04	117
GO:0001945	GO:0001945	lymph vessel development	12/1494	18/8380	3.74	6.34e-06	4.04e-04	18
GO:0001655	GO:0001655	urogenital system development	72/1494	247/8380	1.64	6.39e-06	4.04e-04	247
GO:0031589	GO:0031589	cell-substrate adhesion	69/1494	234/8380	1.65	6.45e-06	4.04e-04	234
GO:0016525	GO:0016525	negative regulation of angiogenesis	28/1494	69/8380	2.28	7.43e-06	4.52e-04	69
GO:1901343	GO:1901343	negative regulation of vasculature development	31/1494	80/8380	2.17	7.63e-06	4.53e-04	80
GO:0014031	GO:0014031	mesenchymal cell development	26/1494	62/8380	2.35	7.69e-06	4.53e-04	62
GO:0007507	GO:0007507	heart development	91/1494	333/8380	1.53	7.79e-06	4.53e-04	333
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	68/1494	231/8380	1.65	8.01e-06	4.59e-04	231
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	25/1494	59/8380	2.38	9.21e-06	5.13e-04	59
GO:0060840	GO:0060840	artery development	25/1494	59/8380	2.38	9.21e-06	5.13e-04	59
GO:0001885	GO:0001885	endothelial cell development	18/1494	36/8380	2.80	1.04e-05	5.72e-04	36
GO:0008015	GO:0008015	blood circulation	95/1494	354/8380	1.51	1.11e-05	6.04e-04	354
GO:0022604	GO:0022604	regulation of cell morphogenesis	82/1494	296/8380	1.55	1.27e-05	6.79e-04	296
GO:0003170	GO:0003170	heart valve development	20/1494	43/8380	2.61	1.35e-05	7.16e-04	43
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	28/1494	71/8380	2.21	1.42e-05	7.38e-04	71
GO:0002576	GO:0002576	platelet degranulation	32/1494	86/8380	2.09	1.47e-05	7.47e-04	86
GO:0048010	GO:0048010	vascular endothelial growth factor receptor signaling pathway	22/1494	50/8380	2.47	1.53e-05	7.68e-04	50
GO:0051480	GO:0051480	regulation of cytosolic calcium ion concentration	73/1494	259/8380	1.58	2.00e-05	9.92e-04	259
GO:0001822	GO:0001822	kidney development	61/1494	207/8380	1.65	2.24e-05	1.09e-03	207
GO:0003007	GO:0003007	heart morphogenesis	54/1494	177/8380	1.71	2.27e-05	1.09e-03	177
GO:0007219	GO:0007219	Notch signaling pathway	39/1494	115/8380	1.90	2.27e-05	1.09e-03	115
GO:0036303	GO:0036303	lymph vessel morphogenesis	9/1494	12/8380	4.21	2.33e-05	1.10e-03	12
GO:0043087	GO:0043087	regulation of GTPase activity	69/1494	244/8380	1.59	2.99e-05	1.36e-03	244
GO:0045926	GO:0045926	negative regulation of growth	50/1494	162/8380	1.73	3.21e-05	1.45e-03	162
GO:0043536	GO:0043536	positive regulation of blood vessel endothelial cell migration	16/1494	32/8380	2.80	3.24e-05	1.45e-03	32
GO:0001937	GO:0001937	negative regulation of endothelial cell proliferation	13/1494	23/8380	3.17	3.37e-05	1.49e-03	23
GO:0048659	GO:0048659	smooth muscle cell proliferation	34/1494	97/8380	1.97	3.47e-05	1.51e-03	97
GO:0072132	GO:0072132	mesenchyme morphogenesis	18/1494	39/8380	2.59	4.16e-05	1.78e-03	39
GO:0045766	GO:0045766	positive regulation of angiogenesis	37/1494	110/8380	1.89	4.47e-05	1.88e-03	110
GO:0007265	GO:0007265	Ras protein signal transduction	64/1494	225/8380	1.60	4.75e-05	1.97e-03	225
GO:0034329	GO:0034329	cell junction assembly	44/1494	139/8380	1.78	4.81e-05	1.97e-03	139
GO:0014033	GO:0014033	neural crest cell differentiation	25/1494	64/8380	2.19	4.88e-05	1.97e-03	64
GO:0001503	GO:0001503	ossification	70/1494	252/8380	1.56	4.94e-05	1.97e-03	252
GO:0033002	GO:0033002	muscle cell proliferation	43/1494	135/8380	1.79	4.96e-05	1.97e-03	135
GO:0043112	GO:0043112	receptor metabolic process	32/1494	91/8380	1.97	5.43e-05	2.14e-03	91
GO:0048846	GO:0048846	axon extension involved in axon guidance	15/1494	30/8380	2.80	5.73e-05	2.21e-03	30
GO:1902284	GO:1902284	neuron projection extension involved in neuron projection guidance	15/1494	30/8380	2.80	5.73e-05	2.21e-03	30
GO:0061437	GO:0061437	renal system vasculature development	12/1494	21/8380	3.21	5.91e-05	2.24e-03	21
GO:0061440	GO:0061440	kidney vasculature development	12/1494	21/8380	3.21	5.91e-05	2.24e-03	21
GO:0003179	GO:0003179	heart valve morphogenesis	18/1494	40/8380	2.52	6.31e-05	2.28e-03	40
GO:0001837	GO:0001837	epithelial to mesenchymal transition	30/1494	84/8380	2.00	6.62e-05	2.37e-03	84
GO:0014909	GO:0014909	smooth muscle cell migration	20/1494	47/8380	2.39	6.66e-05	2.37e-03	47
GO:0048660	GO:0048660	regulation of smooth muscle cell proliferation	33/1494	96/8380	1.93	7.01e-05	2.44e-03	96
GO:0003206	GO:0003206	cardiac chamber morphogenesis	34/1494	100/8380	1.91	7.04e-05	2.44e-03	100
GO:0014032	GO:0014032	neural crest cell development	23/1494	58/8380	2.22	7.36e-05	2.53e-03	58
GO:0051271	GO:0051271	negative regulation of cellular component movement	59/1494	206/8380	1.61	7.51e-05	2.55e-03	206
GO:0007229	GO:0007229	integrin-mediated signaling pathway	27/1494	73/8380	2.07	7.60e-05	2.56e-03	73
GO:0035150	GO:0035150	regulation of tube size	34/1494	101/8380	1.89	8.83e-05	2.89e-03	101
GO:0050880	GO:0050880	regulation of blood vessel size	34/1494	101/8380	1.89	8.83e-05	2.89e-03	101
GO:0003177	GO:0003177	pulmonary valve development	10/1494	16/8380	3.51	8.87e-05	2.89e-03	16
GO:0001946	GO:0001946	lymphangiogenesis	8/1494	11/8380	4.08	9.92e-05	3.19e-03	11
GO:0040013	GO:0040013	negative regulation of locomotion	59/1494	208/8380	1.59	1.01e-04	3.19e-03	208
GO:1905314	GO:1905314	semi-lunar valve development	14/1494	28/8380	2.80	1.02e-04	3.19e-03	28
GO:0006909	GO:0006909	phagocytosis	44/1494	143/8380	1.73	1.02e-04	3.19e-03	143
GO:0072012	GO:0072012	glomerulus vasculature development	11/1494	19/8380	3.25	1.03e-04	3.20e-03	19
GO:0051928	GO:0051928	positive regulation of calcium ion transport	28/1494	78/8380	2.01	1.04e-04	3.20e-03	78
GO:1901888	GO:1901888	regulation of cell junction assembly	19/1494	45/8380	2.37	1.15e-04	3.49e-03	45
GO:0003205	GO:0003205	cardiac chamber development	38/1494	119/8380	1.79	1.26e-04	3.80e-03	119
GO:0030308	GO:0030308	negative regulation of cell growth	36/1494	111/8380	1.82	1.32e-04	3.96e-03	111
GO:0030168	GO:0030168	platelet activation	34/1494	103/8380	1.85	1.37e-04	4.05e-03	103
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	18/1494	42/8380	2.40	1.37e-04	4.05e-03	42
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	30/1494	87/8380	1.93	1.38e-04	4.05e-03	87
GO:0007160	GO:0007160	cell-matrix adhesion	45/1494	150/8380	1.68	1.65e-04	4.72e-03	150
GO:0042116	GO:0042116	macrophage activation	22/1494	57/8380	2.16	1.68e-04	4.79e-03	57
GO:0003203	GO:0003203	endocardial cushion morphogenesis	13/1494	26/8380	2.80	1.80e-04	5.02e-03	26
GO:0060317	GO:0060317	cardiac epithelial to mesenchymal transition	13/1494	26/8380	2.80	1.80e-04	5.02e-03	26
GO:0048864	GO:0048864	stem cell development	23/1494	61/8380	2.11	1.82e-04	5.04e-03	61
GO:0014808	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	12/1494	23/8380	2.93	1.91e-04	5.15e-03	23
GO:1902668	GO:1902668	negative regulation of axon guidance	12/1494	23/8380	2.93	1.91e-04	5.15e-03	23
GO:0032103	GO:0032103	positive regulation of response to external stimulus	58/1494	208/8380	1.56	1.91e-04	5.15e-03	208
GO:0050918	GO:0050918	positive chemotaxis	21/1494	54/8380	2.18	2.08e-04	5.49e-03	54
GO:0035296	GO:0035296	regulation of tube diameter	32/1494	97/8380	1.85	2.16e-04	5.58e-03	97
GO:0097746	GO:0097746	regulation of blood vessel diameter	32/1494	97/8380	1.85	2.16e-04	5.58e-03	97
GO:0048863	GO:0048863	stem cell differentiation	42/1494	139/8380	1.69	2.26e-04	5.81e-03	139
GO:0051145	GO:0051145	smooth muscle cell differentiation	17/1494	40/8380	2.38	2.37e-04	6.02e-03	40
GO:0051004	GO:0051004	regulation of lipoprotein lipase activity	8/1494	12/8380	3.74	2.51e-04	6.34e-03	12
GO:0032102	GO:0032102	negative regulation of response to external stimulus	59/1494	215/8380	1.54	2.70e-04	6.72e-03	215
GO:0051100	GO:0051100	negative regulation of binding	29/1494	86/8380	1.89	2.75e-04	6.83e-03	86
GO:0014910	GO:0014910	regulation of smooth muscle cell migration	18/1494	44/8380	2.29	2.79e-04	6.86e-03	44
GO:0072006	GO:0072006	nephron development	36/1494	115/8380	1.76	2.91e-04	6.96e-03	115
GO:0001774	GO:0001774	microglial cell activation	13/1494	27/8380	2.70	2.91e-04	6.96e-03	27
GO:0002269	GO:0002269	leukocyte activation involved in inflammatory response	13/1494	27/8380	2.70	2.91e-04	6.96e-03	27
GO:0050922	GO:0050922	negative regulation of chemotaxis	19/1494	48/8380	2.22	3.16e-04	7.39e-03	48
GO:0003184	GO:0003184	pulmonary valve morphogenesis	9/1494	15/8380	3.37	3.16e-04	7.39e-03	15
GO:0010882	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	9/1494	15/8380	3.37	3.16e-04	7.39e-03	15
GO:0003151	GO:0003151	outflow tract morphogenesis	23/1494	63/8380	2.05	3.17e-04	7.39e-03	63
GO:1903514	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	12/1494	24/8380	2.80	3.20e-04	7.42e-03	24
GO:0003197	GO:0003197	endocardial cushion development	15/1494	34/8380	2.47	3.36e-04	7.70e-03	34
GO:0048843	GO:0048843	negative regulation of axon extension involved in axon guidance	11/1494	21/8380	2.94	3.40e-04	7.76e-03	21
GO:0061311	GO:0061311	cell surface receptor signaling pathway involved in heart development	10/1494	18/8380	3.12	3.42e-04	7.76e-03	18
GO:0019935	GO:0019935	cyclic-nucleotide-mediated signaling	46/1494	159/8380	1.62	3.51e-04	7.92e-03	159
GO:0014812	GO:0014812	muscle cell migration	21/1494	56/8380	2.10	3.74e-04	8.40e-03	56
GO:0030336	GO:0030336	negative regulation of cell migration	49/1494	173/8380	1.59	3.95e-04	8.81e-03	173
GO:0001886	GO:0001886	endothelial cell morphogenesis	7/1494	10/8380	3.93	4.10e-04	9.07e-03	10
GO:0050921	GO:0050921	positive regulation of chemotaxis	31/1494	96/8380	1.81	4.11e-04	9.07e-03	96
GO:0046683	GO:0046683	response to organophosphorus	30/1494	92/8380	1.83	4.20e-04	9.07e-03	92
GO:0106106	GO:0106106	cold-induced thermogenesis	30/1494	92/8380	1.83	4.20e-04	9.07e-03	92
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	30/1494	92/8380	1.83	4.20e-04	9.07e-03	92
GO:0046578	GO:0046578	regulation of Ras protein signal transduction	39/1494	130/8380	1.68	4.38e-04	9.35e-03	130
GO:0071526	GO:0071526	semaphorin-plexin signaling pathway	13/1494	28/8380	2.60	4.55e-04	9.67e-03	28
GO:0071559	GO:0071559	response to transforming growth factor beta	41/1494	139/8380	1.65	4.66e-04	9.85e-03	139
GO:0002448	GO:0002448	mast cell mediated immunity	15/1494	35/8380	2.40	4.92e-04	1.02e-02	35
GO:0035904	GO:0035904	aorta development	15/1494	35/8380	2.40	4.92e-04	1.02e-02	35
GO:1990845	GO:1990845	adaptive thermogenesis	31/1494	97/8380	1.79	5.03e-04	1.04e-02	97
GO:0001974	GO:0001974	blood vessel remodeling	12/1494	25/8380	2.69	5.17e-04	1.05e-02	25
GO:0048841	GO:0048841	regulation of axon extension involved in axon guidance	12/1494	25/8380	2.69	5.17e-04	1.05e-02	25
GO:0070296	GO:0070296	sarcoplasmic reticulum calcium ion transport	12/1494	25/8380	2.69	5.17e-04	1.05e-02	25
GO:0034330	GO:0034330	cell junction organization	49/1494	175/8380	1.57	5.27e-04	1.06e-02	175
GO:0045123	GO:0045123	cellular extravasation	18/1494	46/8380	2.19	5.32e-04	1.07e-02	46
GO:0010881	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	8/1494	13/8380	3.45	5.50e-04	1.09e-02	13
GO:1902547	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	8/1494	13/8380	3.45	5.50e-04	1.09e-02	13
GO:1903978	GO:1903978	regulation of microglial cell activation	8/1494	13/8380	3.45	5.50e-04	1.09e-02	13
GO:0071675	GO:0071675	regulation of mononuclear cell migration	14/1494	32/8380	2.45	5.86e-04	1.15e-02	32
GO:0010880	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	10/1494	19/8380	2.95	6.08e-04	1.19e-02	19
GO:0032693	GO:0032693	negative regulation of interleukin-10 production	9/1494	16/8380	3.16	6.08e-04	1.19e-02	16
GO:0030856	GO:0030856	regulation of epithelial cell differentiation	30/1494	94/8380	1.79	6.32e-04	1.22e-02	94
GO:0003208	GO:0003208	cardiac ventricle morphogenesis	21/1494	58/8380	2.03	6.47e-04	1.24e-02	58
GO:0060411	GO:0060411	cardiac septum morphogenesis	21/1494	58/8380	2.03	6.47e-04	1.24e-02	58
GO:0030595	GO:0030595	leukocyte chemotaxis	48/1494	172/8380	1.57	6.49e-04	1.24e-02	172
GO:0051056	GO:0051056	regulation of small GTPase mediated signal transduction	52/1494	190/8380	1.54	6.51e-04	1.24e-02	190
GO:0019722	GO:0019722	calcium-mediated signaling	43/1494	150/8380	1.61	6.66e-04	1.26e-02	150
GO:0003279	GO:0003279	cardiac septum development	25/1494	74/8380	1.89	6.88e-04	1.30e-02	74
GO:0043300	GO:0043300	regulation of leukocyte degranulation	13/1494	29/8380	2.51	6.92e-04	1.30e-02	29
GO:0071621	GO:0071621	granulocyte chemotaxis	31/1494	99/8380	1.76	7.43e-04	1.38e-02	99
GO:0007162	GO:0007162	negative regulation of cell adhesion	48/1494	173/8380	1.56	7.46e-04	1.38e-02	173
GO:0045665	GO:0045665	negative regulation of neuron differentiation	43/1494	151/8380	1.60	7.74e-04	1.41e-02	151
GO:0001659	GO:0001659	temperature homeostasis	34/1494	112/8380	1.70	7.87e-04	1.43e-02	112
GO:0071560	GO:0071560	cellular response to transforming growth factor beta stimulus	39/1494	134/8380	1.63	8.44e-04	1.52e-02	134
GO:0051924	GO:0051924	regulation of calcium ion transport	46/1494	165/8380	1.56	8.52e-04	1.52e-02	165
GO:0060412	GO:0060412	ventricular septum morphogenesis	14/1494	33/8380	2.38	8.53e-04	1.52e-02	33
GO:1902667	GO:1902667	regulation of axon guidance	14/1494	33/8380	2.38	8.53e-04	1.52e-02	33
GO:2000351	GO:2000351	regulation of endothelial cell apoptotic process	14/1494	33/8380	2.38	8.53e-04	1.52e-02	33
GO:0010977	GO:0010977	negative regulation of neuron projection development	31/1494	100/8380	1.74	8.96e-04	1.57e-02	100
GO:0014074	GO:0014074	response to purine-containing compound	31/1494	100/8380	1.74	8.96e-04	1.57e-02	100
GO:0051098	GO:0051098	regulation of binding	49/1494	179/8380	1.54	9.15e-04	1.59e-02	179
GO:0035909	GO:0035909	aorta morphogenesis	11/1494	23/8380	2.68	9.20e-04	1.59e-02	23
GO:0090075	GO:0090075	relaxation of muscle	11/1494	23/8380	2.68	9.20e-04	1.59e-02	23
GO:0002685	GO:0002685	regulation of leukocyte migration	40/1494	139/8380	1.61	9.30e-04	1.60e-02	139
GO:0061081	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	7/1494	11/8380	3.57	9.53e-04	1.63e-02	11
GO:0072109	GO:0072109	glomerular mesangium development	7/1494	11/8380	3.57	9.53e-04	1.63e-02	11
GO:0097530	GO:0097530	granulocyte migration	33/1494	109/8380	1.70	9.83e-04	1.67e-02	109
GO:0002042	GO:0002042	cell migration involved in sprouting angiogenesis	15/1494	37/8380	2.27	9.93e-04	1.67e-02	37
GO:0043030	GO:0043030	regulation of macrophage activation	15/1494	37/8380	2.27	9.93e-04	1.67e-02	37
GO:0071320	GO:0071320	cellular response to cAMP	15/1494	37/8380	2.27	9.93e-04	1.67e-02	37
GO:0033627	GO:0033627	cell adhesion mediated by integrin	19/1494	52/8380	2.05	1.02e-03	1.69e-02	52
GO:0043032	GO:0043032	positive regulation of macrophage activation	10/1494	20/8380	2.80	1.02e-03	1.69e-02	20
GO:0045601	GO:0045601	regulation of endothelial cell differentiation	10/1494	20/8380	2.80	1.02e-03	1.69e-02	20
GO:0002011	GO:0002011	morphogenesis of an epithelial sheet	13/1494	30/8380	2.43	1.02e-03	1.69e-02	30
GO:0046677	GO:0046677	response to antibiotic	49/1494	180/8380	1.53	1.05e-03	1.71e-02	180
GO:0008361	GO:0008361	regulation of cell size	31/1494	101/8380	1.72	1.08e-03	1.73e-02	101
GO:0035589	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	8/1494	14/8380	3.21	1.08e-03	1.73e-02	14
GO:0150078	GO:0150078	positive regulation of neuroinflammatory response	8/1494	14/8380	3.21	1.08e-03	1.73e-02	14
GO:0072010	GO:0072010	glomerular epithelium development	9/1494	17/8380	2.97	1.09e-03	1.73e-02	17
GO:0010522	GO:0010522	regulation of calcium ion transport into cytosol	23/1494	68/8380	1.90	1.09e-03	1.73e-02	68
GO:0051591	GO:0051591	response to cAMP	23/1494	68/8380	1.90	1.09e-03	1.73e-02	68
GO:0050663	GO:0050663	cytokine secretion	42/1494	149/8380	1.58	1.11e-03	1.75e-02	149
GO:2000146	GO:2000146	negative regulation of cell motility	49/1494	181/8380	1.52	1.19e-03	1.87e-02	181
GO:0001755	GO:0001755	neural crest cell migration	17/1494	45/8380	2.12	1.20e-03	1.87e-02	45
GO:0097755	GO:0097755	positive regulation of blood vessel diameter	17/1494	45/8380	2.12	1.20e-03	1.87e-02	45
GO:0010324	GO:0010324	membrane invagination	14/1494	34/8380	2.31	1.22e-03	1.87e-02	34
GO:1903391	GO:1903391	regulation of adherens junction organization	14/1494	34/8380	2.31	1.22e-03	1.87e-02	34
GO:0010543	GO:0010543	regulation of platelet activation	12/1494	27/8380	2.49	1.22e-03	1.87e-02	27
GO:0045806	GO:0045806	negative regulation of endocytosis	12/1494	27/8380	2.49	1.22e-03	1.87e-02	27
GO:0042542	GO:0042542	response to hydrogen peroxide	23/1494	69/8380	1.87	1.37e-03	2.07e-02	69
GO:0071674	GO:0071674	mononuclear cell migration	23/1494	69/8380	1.87	1.37e-03	2.07e-02	69
GO:0016486	GO:0016486	peptide hormone processing	11/1494	24/8380	2.57	1.43e-03	2.15e-02	24
GO:0061028	GO:0061028	establishment of endothelial barrier	11/1494	24/8380	2.57	1.43e-03	2.15e-02	24
GO:0006911	GO:0006911	phagocytosis, engulfment	13/1494	31/8380	2.35	1.48e-03	2.21e-02	31
GO:0030593	GO:0030593	neutrophil chemotaxis	27/1494	86/8380	1.76	1.52e-03	2.26e-02	86
GO:0010644	GO:0010644	cell communication by electrical coupling	10/1494	21/8380	2.67	1.64e-03	2.41e-02	21
GO:0035767	GO:0035767	endothelial cell chemotaxis	10/1494	21/8380	2.67	1.64e-03	2.41e-02	21
GO:0150077	GO:0150077	regulation of neuroinflammatory response	10/1494	21/8380	2.67	1.64e-03	2.41e-02	21
GO:0050771	GO:0050771	negative regulation of axonogenesis	18/1494	50/8380	2.02	1.66e-03	2.43e-02	50
GO:0010718	GO:0010718	positive regulation of epithelial to mesenchymal transition	14/1494	35/8380	2.24	1.70e-03	2.46e-02	35
GO:0072577	GO:0072577	endothelial cell apoptotic process	14/1494	35/8380	2.24	1.70e-03	2.46e-02	35
GO:0007266	GO:0007266	Rho protein signal transduction	35/1494	121/8380	1.62	1.71e-03	2.46e-02	121
GO:1902905	GO:1902905	positive regulation of supramolecular fiber organization	32/1494	108/8380	1.66	1.73e-03	2.46e-02	108
GO:0017015	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	20/1494	58/8380	1.93	1.73e-03	2.46e-02	58
GO:0042310	GO:0042310	vasoconstriction	20/1494	58/8380	1.93	1.73e-03	2.46e-02	58
GO:1904019	GO:1904019	epithelial cell apoptotic process	20/1494	58/8380	1.93	1.73e-03	2.46e-02	58
GO:0060976	GO:0060976	coronary vasculature development	12/1494	28/8380	2.40	1.79e-03	2.54e-02	28
GO:0003272	GO:0003272	endocardial cushion formation	9/1494	18/8380	2.80	1.84e-03	2.57e-02	18
GO:0035886	GO:0035886	vascular smooth muscle cell differentiation	9/1494	18/8380	2.80	1.84e-03	2.57e-02	18
GO:0071868	GO:0071868	cellular response to monoamine stimulus	9/1494	18/8380	2.80	1.84e-03	2.57e-02	18
GO:0071870	GO:0071870	cellular response to catecholamine stimulus	9/1494	18/8380	2.80	1.84e-03	2.57e-02	18
GO:0003198	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	7/1494	12/8380	3.27	1.94e-03	2.65e-02	12
GO:0072148	GO:0072148	epithelial cell fate commitment	7/1494	12/8380	3.27	1.94e-03	2.65e-02	12
GO:1900746	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	7/1494	12/8380	3.27	1.94e-03	2.65e-02	12
GO:0044319	GO:0044319	wound healing, spreading of cells	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:0046068	GO:0046068	cGMP metabolic process	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:0090504	GO:0090504	epiboly	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:0090505	GO:0090505	epiboly involved in wound healing	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:1904738	GO:1904738	vascular associated smooth muscle cell migration	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:1904752	GO:1904752	regulation of vascular associated smooth muscle cell migration	8/1494	15/8380	2.99	1.96e-03	2.65e-02	15
GO:0007179	GO:0007179	transforming growth factor beta receptor signaling pathway	29/1494	96/8380	1.69	2.01e-03	2.71e-02	96
GO:0007369	GO:0007369	gastrulation	32/1494	109/8380	1.65	2.04e-03	2.73e-02	109
GO:0048675	GO:0048675	axon extension	23/1494	71/8380	1.82	2.09e-03	2.78e-02	71
GO:0051495	GO:0051495	positive regulation of cytoskeleton organization	34/1494	118/8380	1.62	2.12e-03	2.81e-02	118
GO:1903034	GO:1903034	regulation of response to wounding	31/1494	105/8380	1.66	2.15e-03	2.84e-02	105
GO:0051279	GO:0051279	regulation of release of sequestered calcium ion into cytosol	19/1494	55/8380	1.94	2.18e-03	2.86e-02	55
GO:1903844	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	20/1494	59/8380	1.90	2.19e-03	2.86e-02	59
GO:0035023	GO:0035023	regulation of Rho protein signal transduction	26/1494	84/8380	1.74	2.31e-03	3.01e-02	84
GO:1904705	GO:1904705	regulation of vascular smooth muscle cell proliferation	14/1494	36/8380	2.18	2.33e-03	3.02e-02	36
GO:1990874	GO:1990874	vascular smooth muscle cell proliferation	14/1494	36/8380	2.18	2.33e-03	3.02e-02	36
GO:0048771	GO:0048771	tissue remodeling	32/1494	110/8380	1.63	2.39e-03	3.08e-02	110
GO:0072089	GO:0072089	stem cell proliferation	24/1494	76/8380	1.77	2.49e-03	3.16e-02	76
GO:0003231	GO:0003231	cardiac ventricle development	28/1494	93/8380	1.69	2.52e-03	3.16e-02	93
GO:0061041	GO:0061041	regulation of wound healing	28/1494	93/8380	1.69	2.52e-03	3.16e-02	93
GO:1990266	GO:1990266	neutrophil migration	28/1494	93/8380	1.69	2.52e-03	3.16e-02	93
GO:0071695	GO:0071695	anatomical structure maturation	31/1494	106/8380	1.64	2.53e-03	3.16e-02	106
GO:0003176	GO:0003176	aortic valve development	10/1494	22/8380	2.55	2.54e-03	3.16e-02	22
GO:0043114	GO:0043114	regulation of vascular permeability	10/1494	22/8380	2.55	2.54e-03	3.16e-02	22
GO:0019933	GO:0019933	cAMP-mediated signaling	38/1494	137/8380	1.56	2.55e-03	3.17e-02	137
GO:0120163	GO:0120163	negative regulation of cold-induced thermogenesis	12/1494	29/8380	2.32	2.56e-03	3.18e-02	29
GO:0031345	GO:0031345	negative regulation of cell projection organization	33/1494	115/8380	1.61	2.63e-03	3.24e-02	115
GO:0010771	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	22/1494	68/8380	1.81	2.64e-03	3.24e-02	68
GO:1904427	GO:1904427	positive regulation of calcium ion transmembrane transport	17/1494	48/8380	1.99	2.71e-03	3.32e-02	48
GO:0097756	GO:0097756	negative regulation of blood vessel diameter	20/1494	60/8380	1.87	2.74e-03	3.34e-02	60
GO:0032091	GO:0032091	negative regulation of protein binding	19/1494	56/8380	1.90	2.76e-03	3.36e-02	56
GO:0030517	GO:0030517	negative regulation of axon extension	13/1494	33/8380	2.21	2.89e-03	3.45e-02	33
GO:0032387	GO:0032387	negative regulation of intracellular transport	13/1494	33/8380	2.21	2.89e-03	3.45e-02	33
GO:0043303	GO:0043303	mast cell degranulation	13/1494	33/8380	2.21	2.89e-03	3.45e-02	33
GO:0061900	GO:0061900	glial cell activation	13/1494	33/8380	2.21	2.89e-03	3.45e-02	33
GO:0099024	GO:0099024	plasma membrane invagination	13/1494	33/8380	2.21	2.89e-03	3.45e-02	33
GO:0006939	GO:0006939	smooth muscle contraction	25/1494	81/8380	1.73	2.90e-03	3.45e-02	81
GO:0002064	GO:0002064	epithelial cell development	36/1494	129/8380	1.57	2.92e-03	3.47e-02	129
GO:0003171	GO:0003171	atrioventricular valve development	9/1494	19/8380	2.66	2.94e-03	3.49e-02	19
GO:0007043	GO:0007043	cell-cell junction assembly	24/1494	77/8380	1.75	3.02e-03	3.54e-02	77
GO:0090049	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	11/1494	26/8380	2.37	3.12e-03	3.65e-02	26
GO:0035850	GO:0035850	epithelial cell differentiation involved in kidney development	14/1494	37/8380	2.12	3.14e-03	3.66e-02	37
GO:1903169	GO:1903169	regulation of calcium ion transmembrane transport	30/1494	103/8380	1.63	3.15e-03	3.66e-02	103
GO:0045648	GO:0045648	positive regulation of erythrocyte differentiation	8/1494	16/8380	2.80	3.32e-03	3.79e-02	16
GO:0086064	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	8/1494	16/8380	2.80	3.32e-03	3.79e-02	16
GO:0090050	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	8/1494	16/8380	2.80	3.32e-03	3.79e-02	16
GO:1904706	GO:1904706	negative regulation of vascular smooth muscle cell proliferation	8/1494	16/8380	2.80	3.32e-03	3.79e-02	16
GO:0030516	GO:0030516	regulation of axon extension	19/1494	57/8380	1.87	3.46e-03	3.89e-02	57
GO:0010935	GO:0010935	regulation of macrophage cytokine production	6/1494	10/8380	3.37	3.47e-03	3.89e-02	10
GO:0030852	GO:0030852	regulation of granulocyte differentiation	6/1494	10/8380	3.37	3.47e-03	3.89e-02	10
GO:0045618	GO:0045618	positive regulation of keratinocyte differentiation	6/1494	10/8380	3.37	3.47e-03	3.89e-02	10
GO:0060841	GO:0060841	venous blood vessel development	6/1494	10/8380	3.37	3.47e-03	3.89e-02	10
GO:0032945	GO:0032945	negative regulation of mononuclear cell proliferation	17/1494	49/8380	1.95	3.48e-03	3.89e-02	49
GO:0050672	GO:0050672	negative regulation of lymphocyte proliferation	17/1494	49/8380	1.95	3.48e-03	3.89e-02	49
GO:0010919	GO:0010919	regulation of inositol phosphate biosynthetic process	7/1494	13/8380	3.02	3.55e-03	3.94e-02	13
GO:0090280	GO:0090280	positive regulation of calcium ion import	7/1494	13/8380	3.02	3.55e-03	3.94e-02	13
GO:0010810	GO:0010810	regulation of cell-substrate adhesion	37/1494	135/8380	1.54	3.60e-03	3.98e-02	135
GO:0090288	GO:0090288	negative regulation of cellular response to growth factor stimulus	27/1494	91/8380	1.66	3.74e-03	4.12e-02	91
GO:0030866	GO:0030866	cortical actin cytoskeleton organization	10/1494	23/8380	2.44	3.78e-03	4.13e-02	23
GO:0050926	GO:0050926	regulation of positive chemotaxis	10/1494	23/8380	2.44	3.78e-03	4.13e-02	23
GO:0002279	GO:0002279	mast cell activation involved in immune response	13/1494	34/8380	2.14	3.93e-03	4.29e-02	34
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	26/1494	87/8380	1.68	3.94e-03	4.29e-02	87
GO:0022408	GO:0022408	negative regulation of cell-cell adhesion	31/1494	109/8380	1.60	4.05e-03	4.37e-02	109
GO:1903531	GO:1903531	negative regulation of secretion by cell	35/1494	127/8380	1.55	4.13e-03	4.44e-02	127
GO:0048662	GO:0048662	negative regulation of smooth muscle cell proliferation	14/1494	38/8380	2.07	4.17e-03	4.47e-02	38
GO:0048661	GO:0048661	positive regulation of smooth muscle cell proliferation	19/1494	58/8380	1.84	4.30e-03	4.56e-02	58
GO:1904035	GO:1904035	regulation of epithelial cell apoptotic process	16/1494	46/8380	1.95	4.40e-03	4.62e-02	46
GO:0021954	GO:0021954	central nervous system neuron development	17/1494	50/8380	1.91	4.41e-03	4.62e-02	50
GO:0002687	GO:0002687	positive regulation of leukocyte migration	27/1494	92/8380	1.65	4.41e-03	4.62e-02	92
GO:0030857	GO:0030857	negative regulation of epithelial cell differentiation	11/1494	27/8380	2.29	4.43e-03	4.62e-02	27
GO:0006929	GO:0006929	substrate-dependent cell migration	9/1494	20/8380	2.52	4.51e-03	4.63e-02	20
GO:0043304	GO:0043304	regulation of mast cell degranulation	9/1494	20/8380	2.52	4.51e-03	4.63e-02	20
GO:0045773	GO:0045773	positive regulation of axon extension	9/1494	20/8380	2.52	4.51e-03	4.63e-02	20
GO:0048245	GO:0048245	eosinophil chemotaxis	9/1494	20/8380	2.52	4.51e-03	4.63e-02	20
GO:0086011	GO:0086011	membrane repolarization during action potential	9/1494	20/8380	2.52	4.51e-03	4.63e-02	20
GO:0050866	GO:0050866	negative regulation of cell activation	35/1494	128/8380	1.53	4.74e-03	4.82e-02	128

Summary:
Factor	1	2	3	4	5	6	7	8	9	10
Signif_GO_terms	0	11	5	125	914	2	2	0	26	75
Factor	11	12	13	14	15	16	17	18	19	20
Signif_GO_terms	12	59	1	760	2	614	257	587	0	324

3.1.1 Factors of interest

4: connective tissue development; tissue migration; endothelial cell proliferation
5: activation of immune response
12: microtubule-based movement; synaptic vesicle cycle
14: blood vessel development; endothelial cell proliferation
16: activation of immune response
17: cell division, mitotic cell cycle
18: activation of immune response
20: blood vessel development; endothelium development

3.2 GO enrichment per driver gene condition

Target: Genes w/ GSFA lfsr < 0.05 under each condition, stratefied by sign of effect;
Backgroud: all 10000 genes used in factor analysis.

GO terms that passed over-representation test fold change \(\geq\) 1.5 and q value \(<\) 0.05:

TP53_LOF_up : 122 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	191/3095	309/8380	1.67	1.47e-19	6.84e-16	309
GO:0000278	GO:0000278	mitotic cell cycle	219/3095	370/8380	1.60	5.49e-19	1.28e-15	370
GO:0007059	GO:0007059	chromosome segregation	90/3095	126/8380	1.93	2.48e-15	3.84e-12	126
GO:0000819	GO:0000819	sister chromatid segregation	61/3095	76/8380	2.17	1.02e-14	1.18e-11	76
GO:0000070	GO:0000070	mitotic sister chromatid segregation	51/3095	60/8380	2.30	1.82e-14	1.56e-11	60
GO:0098813	GO:0098813	nuclear chromosome segregation	81/3095	112/8380	1.96	2.01e-14	1.56e-11	112
GO:0006260	GO:0006260	DNA replication	72/3095	96/8380	2.03	2.56e-14	1.70e-11	96
GO:0000280	GO:0000280	nuclear division	124/3095	198/8380	1.70	1.08e-13	6.26e-11	198
GO:0140014	GO:0140014	mitotic nuclear division	84/3095	122/8380	1.86	5.90e-13	3.05e-10	122
GO:0044772	GO:0044772	mitotic cell cycle phase transition	118/3095	191/8380	1.67	1.66e-12	7.73e-10	191
GO:0048285	GO:0048285	organelle fission	129/3095	215/8380	1.62	3.11e-12	1.21e-09	215
GO:0044770	GO:0044770	cell cycle phase transition	122/3095	206/8380	1.60	4.16e-11	1.49e-08	206
GO:0006261	GO:0006261	DNA-dependent DNA replication	44/3095	55/8380	2.17	7.02e-11	2.33e-08	55
GO:0051301	GO:0051301	cell division	143/3095	255/8380	1.52	2.22e-10	6.46e-08	255
GO:0070268	GO:0070268	cornification	65/3095	95/8380	1.85	3.82e-10	1.05e-07	95
GO:0031424	GO:0031424	keratinization	73/3095	113/8380	1.75	1.79e-09	4.62e-07	113
GO:0071103	GO:0071103	DNA conformation change	76/3095	120/8380	1.71	3.17e-09	7.76e-07	120
GO:0051983	GO:0051983	regulation of chromosome segregation	33/3095	40/8380	2.23	4.10e-09	9.52e-07	40
GO:0030216	GO:0030216	keratinocyte differentiation	93/3095	161/8380	1.56	4.84e-08	9.79e-06	161
GO:0051310	GO:0051310	metaphase plate congression	19/3095	20/8380	2.57	7.59e-08	1.41e-05	20
GO:0034660	GO:0034660	ncRNA metabolic process	59/3095	92/8380	1.74	9.54e-08	1.71e-05	92
GO:0006270	GO:0006270	DNA replication initiation	16/3095	16/8380	2.71	1.17e-07	2.01e-05	16
GO:0034470	GO:0034470	ncRNA processing	39/3095	54/8380	1.96	1.34e-07	2.23e-05	54
GO:1903046	GO:1903046	meiotic cell cycle process	65/3095	105/8380	1.68	1.54e-07	2.48e-05	105
GO:0007051	GO:0007051	spindle organization	43/3095	62/8380	1.88	2.02e-07	3.13e-05	62
GO:0032508	GO:0032508	DNA duplex unwinding	20/3095	22/8380	2.46	2.09e-07	3.14e-05	22
GO:0007080	GO:0007080	mitotic metaphase plate congression	15/3095	15/8380	2.71	3.18e-07	4.48e-05	15
GO:0032392	GO:0032392	DNA geometric change	23/3095	27/8380	2.31	3.30e-07	4.52e-05	27
GO:0051321	GO:0051321	meiotic cell cycle	76/3095	130/8380	1.58	4.17e-07	5.54e-05	130
GO:0140013	GO:0140013	meiotic nuclear division	61/3095	99/8380	1.67	4.70e-07	6.07e-05	99
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	37/3095	52/8380	1.93	5.24e-07	6.58e-05	52
GO:0071219	GO:0071219	cellular response to molecule of bacterial origin	76/3095	131/8380	1.57	6.37e-07	7.80e-05	131
GO:0050000	GO:0050000	chromosome localization	22/3095	26/8380	2.29	7.69e-07	8.94e-05	26
GO:0051303	GO:0051303	establishment of chromosome localization	22/3095	26/8380	2.29	7.69e-07	8.94e-05	26
GO:0071216	GO:0071216	cellular response to biotic stimulus	79/3095	138/8380	1.55	8.13e-07	9.14e-05	138
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	35/3095	49/8380	1.93	9.20e-07	9.95e-05	49
GO:0071222	GO:0071222	cellular response to lipopolysaccharide	73/3095	126/8380	1.57	1.14e-06	1.20e-04	126
GO:0006281	GO:0006281	DNA repair	84/3095	150/8380	1.52	1.30e-06	1.34e-04	150
GO:0007052	GO:0007052	mitotic spindle organization	32/3095	44/8380	1.97	1.42e-06	1.44e-04	44
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	60/3095	100/8380	1.62	2.09e-06	2.05e-04	100
GO:0051304	GO:0051304	chromosome separation	29/3095	39/8380	2.01	2.11e-06	2.05e-04	39
GO:0033045	GO:0033045	regulation of sister chromatid segregation	25/3095	32/8380	2.12	2.31e-06	2.20e-04	32
GO:0034502	GO:0034502	protein localization to chromosome	19/3095	22/8380	2.34	2.48e-06	2.26e-04	22
GO:0007088	GO:0007088	regulation of mitotic nuclear division	55/3095	90/8380	1.65	2.48e-06	2.26e-04	90
GO:0006302	GO:0006302	double-strand break repair	50/3095	80/8380	1.69	2.78e-06	2.49e-04	80
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	47/3095	75/8380	1.70	4.95e-06	4.17e-04	75
GO:0000075	GO:0000075	cell cycle checkpoint	46/3095	73/8380	1.71	5.02e-06	4.17e-04	73
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	21/3095	26/8380	2.19	6.01e-06	4.74e-04	26
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	21/3095	26/8380	2.19	6.01e-06	4.74e-04	26
GO:0051306	GO:0051306	mitotic sister chromatid separation	21/3095	26/8380	2.19	6.01e-06	4.74e-04	26
GO:0044843	GO:0044843	cell cycle G1/S phase transition	63/3095	109/8380	1.56	6.78e-06	5.25e-04	109
GO:0044839	GO:0044839	cell cycle G2/M phase transition	50/3095	82/8380	1.65	7.71e-06	5.79e-04	82
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	73/3095	131/8380	1.51	8.05e-06	5.94e-04	131
GO:0006310	GO:0006310	DNA recombination	59/3095	101/8380	1.58	8.36e-06	5.99e-04	101
GO:0051783	GO:0051783	regulation of nuclear division	59/3095	101/8380	1.58	8.36e-06	5.99e-04	101
GO:0051784	GO:0051784	negative regulation of nuclear division	23/3095	30/8380	2.08	1.05e-05	7.29e-04	30
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	30/3095	43/8380	1.89	1.20e-05	8.09e-04	43
GO:0000725	GO:0000725	recombinational repair	30/3095	43/8380	1.89	1.20e-05	8.09e-04	43
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	20/3095	25/8380	2.17	1.33e-05	8.70e-04	25
GO:0006323	GO:0006323	DNA packaging	56/3095	96/8380	1.58	1.50e-05	9.53e-04	96
GO:0051383	GO:0051383	kinetochore organization	11/3095	11/8380	2.71	1.72e-05	1.08e-03	11
GO:1905818	GO:1905818	regulation of chromosome separation	21/3095	27/8380	2.11	1.76e-05	1.09e-03	27
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	13/3095	14/8380	2.51	2.16e-05	1.32e-03	14
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	34/3095	52/8380	1.77	2.78e-05	1.68e-03	52
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	19/3095	24/8380	2.14	2.91e-05	1.73e-03	24
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/3095	19/8380	2.28	3.17e-05	1.82e-03	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/3095	19/8380	2.28	3.17e-05	1.82e-03	19
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	20/3095	26/8380	2.08	3.75e-05	2.08e-03	26
GO:2001251	GO:2001251	negative regulation of chromosome organization	30/3095	45/8380	1.81	4.75e-05	2.60e-03	45
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	37/3095	59/8380	1.70	4.89e-05	2.65e-03	59
GO:0007062	GO:0007062	sister chromatid cohesion	18/3095	23/8380	2.12	6.30e-05	3.37e-03	23
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/3095	18/8380	2.26	7.30e-05	3.77e-03	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/3095	18/8380	2.26	7.30e-05	3.77e-03	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/3095	18/8380	2.26	7.30e-05	3.77e-03	18
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	19/3095	25/8380	2.06	7.91e-05	4.04e-03	25
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	20/3095	27/8380	2.01	9.44e-05	4.72e-03	27
GO:0061982	GO:0061982	meiosis I cell cycle process	40/3095	67/8380	1.62	1.21e-04	5.92e-03	67
GO:0019730	GO:0019730	antimicrobial humoral response	48/3095	84/8380	1.55	1.22e-04	5.92e-03	84
GO:0051225	GO:0051225	spindle assembly	24/3095	35/8380	1.86	1.40e-04	6.72e-03	35
GO:0045132	GO:0045132	meiotic chromosome segregation	32/3095	51/8380	1.70	1.55e-04	7.36e-03	51
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	14/3095	17/8380	2.23	1.66e-04	7.59e-03	17
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	14/3095	17/8380	2.23	1.66e-04	7.59e-03	17
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	14/3095	17/8380	2.23	1.66e-04	7.59e-03	17
GO:0007127	GO:0007127	meiosis I	38/3095	64/8380	1.61	2.08e-04	9.31e-03	64
GO:0044786	GO:0044786	cell cycle DNA replication	15/3095	19/8380	2.14	2.28e-04	1.01e-02	19
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	12/3095	14/8380	2.32	2.52e-04	1.11e-02	14
GO:0032479	GO:0032479	regulation of type I interferon production	28/3095	44/8380	1.72	2.82e-04	1.21e-02	44
GO:0032606	GO:0032606	type I interferon production	28/3095	44/8380	1.72	2.82e-04	1.21e-02	44
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	26/3095	40/8380	1.76	2.83e-04	1.21e-02	40
GO:0034134	GO:0034134	toll-like receptor 2 signaling pathway	10/3095	11/8380	2.46	3.42e-04	1.41e-02	11
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/3095	11/8380	2.46	3.42e-04	1.41e-02	11
GO:0031497	GO:0031497	chromatin assembly	44/3095	78/8380	1.53	3.43e-04	1.41e-02	78
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	36/3095	61/8380	1.60	3.58e-04	1.45e-02	61
GO:0034508	GO:0034508	centromere complex assembly	18/3095	25/8380	1.95	3.85e-04	1.52e-02	25
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	42/3095	74/8380	1.54	3.89e-04	1.52e-02	74
GO:0006364	GO:0006364	rRNA processing	19/3095	27/8380	1.91	4.24e-04	1.63e-02	27
GO:0000281	GO:0000281	mitotic cytokinesis	20/3095	29/8380	1.87	4.54e-04	1.72e-02	29
GO:0006399	GO:0006399	tRNA metabolic process	14/3095	18/8380	2.11	4.93e-04	1.85e-02	18
GO:0016072	GO:0016072	rRNA metabolic process	23/3095	35/8380	1.78	5.03e-04	1.87e-02	35
GO:0006275	GO:0006275	regulation of DNA replication	24/3095	37/8380	1.76	5.07e-04	1.87e-02	37
GO:0038061	GO:0038061	NIK/NF-kappaB signaling	36/3095	62/8380	1.57	5.54e-04	2.03e-02	62
GO:0000910	GO:0000910	cytokinesis	35/3095	60/8380	1.58	5.85e-04	2.12e-02	60
GO:0006334	GO:0006334	nucleosome assembly	40/3095	71/8380	1.53	6.51e-04	2.35e-02	71
GO:0031055	GO:0031055	chromatin remodeling at centromere	16/3095	22/8380	1.97	6.90e-04	2.47e-02	22
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	29/3095	48/8380	1.64	7.77e-04	2.74e-02	48
GO:0032481	GO:0032481	positive regulation of type I interferon production	18/3095	26/8380	1.87	8.21e-04	2.81e-02	26
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/3095	15/8380	2.17	8.35e-04	2.81e-02	15
GO:0031577	GO:0031577	spindle checkpoint	12/3095	15/8380	2.17	8.35e-04	2.81e-02	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/3095	15/8380	2.17	8.35e-04	2.81e-02	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/3095	15/8380	2.17	8.35e-04	2.81e-02	15
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	23/3095	36/8380	1.73	9.08e-04	3.04e-02	36
GO:1901222	GO:1901222	regulation of NIK/NF-kappaB signaling	32/3095	55/8380	1.58	1.06e-03	3.44e-02	55
GO:0032495	GO:0032495	response to muramyl dipeptide	10/3095	12/8380	2.26	1.37e-03	4.23e-02	12
GO:0035872	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	10/3095	12/8380	2.26	1.37e-03	4.23e-02	12
GO:0070423	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	10/3095	12/8380	2.26	1.37e-03	4.23e-02	12
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	15/3095	21/8380	1.93	1.38e-03	4.23e-02	21
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	15/3095	21/8380	1.93	1.38e-03	4.23e-02	21
GO:0090307	GO:0090307	mitotic spindle assembly	15/3095	21/8380	1.93	1.38e-03	4.23e-02	21
GO:0042254	GO:0042254	ribosome biogenesis	23/3095	37/8380	1.68	1.57e-03	4.67e-02	37
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	23/3095	37/8380	1.68	1.57e-03	4.67e-02	37
GO:0031123	GO:0031123	RNA 3’-end processing	18/3095	27/8380	1.81	1.62e-03	4.76e-02	27
GO:2000779	GO:2000779	regulation of double-strand break repair	18/3095	27/8380	1.81	1.62e-03	4.76e-02	27

TP53_LOF_down : 8 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0035082	GO:0035082	axoneme assembly	35/3073	43/8380	2.22	2.21e-09	1.07e-05	43
GO:0003341	GO:0003341	cilium movement	34/3073	42/8380	2.21	4.94e-09	1.20e-05	42
GO:0044782	GO:0044782	cilium organization	89/3073	151/8380	1.61	1.71e-08	2.76e-05	151
GO:0060271	GO:0060271	cilium assembly	82/3073	140/8380	1.60	9.15e-08	1.11e-04	140
GO:0001578	GO:0001578	microtubule bundle formation	41/3073	58/8380	1.93	1.35e-07	1.31e-04	58
GO:0070286	GO:0070286	axonemal dynein complex assembly	20/3073	23/8380	2.37	9.15e-07	7.11e-04	23
GO:0044458	GO:0044458	motile cilium assembly	12/3073	13/8380	2.52	5.02e-05	1.88e-02	13
GO:0036158	GO:0036158	outer dynein arm assembly	11/3073	12/8380	2.50	1.27e-04	3.63e-02	12

TP53_mis_up : 98 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:1903047	GO:1903047	mitotic cell cycle process	183/3121	309/8380	1.59	1.21e-15	4.00e-12	309
GO:0051276	GO:0051276	chromosome organization	228/3121	406/8380	1.51	1.72e-15	4.00e-12	406
GO:0000278	GO:0000278	mitotic cell cycle	210/3121	370/8380	1.52	5.32e-15	8.23e-12	370
GO:0007059	GO:0007059	chromosome segregation	89/3121	126/8380	1.90	1.89e-14	2.20e-11	126
GO:0006260	GO:0006260	DNA replication	72/3121	96/8380	2.01	4.20e-14	3.90e-11	96
GO:0000819	GO:0000819	sister chromatid segregation	60/3121	76/8380	2.12	1.05e-13	8.14e-11	76
GO:0098813	GO:0098813	nuclear chromosome segregation	79/3121	112/8380	1.89	6.39e-13	4.24e-10	112
GO:0000070	GO:0000070	mitotic sister chromatid segregation	49/3121	60/8380	2.19	1.87e-12	1.09e-09	60
GO:0071103	GO:0071103	DNA conformation change	81/3121	120/8380	1.81	1.29e-11	6.31e-09	120
GO:0006261	GO:0006261	DNA-dependent DNA replication	45/3121	55/8380	2.20	1.36e-11	6.31e-09	55
GO:0044772	GO:0044772	mitotic cell cycle phase transition	115/3121	191/8380	1.62	6.45e-11	2.73e-08	191
GO:0140014	GO:0140014	mitotic nuclear division	80/3121	122/8380	1.76	1.59e-10	6.15e-08	122
GO:0000280	GO:0000280	nuclear division	117/3121	198/8380	1.59	2.34e-10	8.35e-08	198
GO:0051301	GO:0051301	cell division	143/3121	255/8380	1.51	4.37e-10	1.45e-07	255
GO:0044770	GO:0044770	cell cycle phase transition	120/3121	206/8380	1.56	4.82e-10	1.49e-07	206
GO:0051983	GO:0051983	regulation of chromosome segregation	34/3121	40/8380	2.28	6.19e-10	1.80e-07	40
GO:0048285	GO:0048285	organelle fission	122/3121	215/8380	1.52	3.25e-09	8.38e-07	215
GO:0019730	GO:0019730	antimicrobial humoral response	57/3121	84/8380	1.82	1.06e-08	2.60e-06	84
GO:0034660	GO:0034660	ncRNA metabolic process	60/3121	92/8380	1.75	4.24e-08	9.84e-06	92
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	37/3121	49/8380	2.03	5.19e-08	1.15e-05	49
GO:0006270	GO:0006270	DNA replication initiation	16/3121	16/8380	2.69	1.34e-07	2.73e-05	16
GO:0006323	GO:0006323	DNA packaging	61/3121	96/8380	1.71	1.35e-07	2.73e-05	96
GO:0034470	GO:0034470	ncRNA processing	39/3121	54/8380	1.94	1.74e-07	3.37e-05	54
GO:0032508	GO:0032508	DNA duplex unwinding	20/3121	22/8380	2.44	2.45e-07	4.56e-05	22
GO:0032392	GO:0032392	DNA geometric change	23/3121	27/8380	2.29	3.94e-07	7.03e-05	27
GO:0033045	GO:0033045	regulation of sister chromatid segregation	26/3121	32/8380	2.18	4.25e-07	7.32e-05	32
GO:0006281	GO:0006281	DNA repair	85/3121	150/8380	1.52	8.57e-07	1.36e-04	150
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	22/3121	26/8380	2.27	9.08e-07	1.36e-04	26
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	22/3121	26/8380	2.27	9.08e-07	1.36e-04	26
GO:0051306	GO:0051306	mitotic sister chromatid separation	22/3121	26/8380	2.27	9.08e-07	1.36e-04	26
GO:0051321	GO:0051321	meiotic cell cycle	75/3121	130/8380	1.55	1.48e-06	2.14e-04	130
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	21/3121	25/8380	2.26	2.08e-06	2.93e-04	25
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	60/3121	100/8380	1.61	2.86e-06	3.80e-04	100
GO:0034502	GO:0034502	protein localization to chromosome	19/3121	22/8380	2.32	2.87e-06	3.80e-04	22
GO:1905818	GO:1905818	regulation of chromosome separation	22/3121	27/8380	2.19	3.17e-06	4.09e-04	27
GO:0044843	GO:0044843	cell cycle G1/S phase transition	64/3121	109/8380	1.58	3.81e-06	4.79e-04	109
GO:1903046	GO:1903046	meiotic cell cycle process	62/3121	105/8380	1.59	4.16e-06	5.08e-04	105
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	20/3121	24/8380	2.24	4.73e-06	5.64e-04	24
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	21/3121	26/8380	2.17	7.01e-06	7.75e-04	26
GO:0050000	GO:0050000	chromosome localization	21/3121	26/8380	2.17	7.01e-06	7.75e-04	26
GO:0051303	GO:0051303	establishment of chromosome localization	21/3121	26/8380	2.17	7.01e-06	7.75e-04	26
GO:0007062	GO:0007062	sister chromatid cohesion	19/3121	23/8380	2.22	1.07e-05	1.13e-03	23
GO:0140013	GO:0140013	meiotic nuclear division	58/3121	99/8380	1.57	1.18e-05	1.20e-03	99
GO:0051304	GO:0051304	chromosome separation	28/3121	39/8380	1.93	1.19e-05	1.20e-03	39
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	20/3121	25/8380	2.15	1.54e-05	1.47e-03	25
GO:0051310	GO:0051310	metaphase plate congression	17/3121	20/8380	2.28	1.55e-05	1.47e-03	20
GO:0051383	GO:0051383	kinetochore organization	11/3121	11/8380	2.69	1.89e-05	1.76e-03	11
GO:0065004	GO:0065004	protein-DNA complex assembly	56/3121	96/8380	1.57	1.98e-05	1.81e-03	96
GO:0007088	GO:0007088	regulation of mitotic nuclear division	53/3121	90/8380	1.58	2.28e-05	2.03e-03	90
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	13/3121	14/8380	2.49	2.39e-05	2.10e-03	14
GO:0006302	GO:0006302	double-strand break repair	48/3121	80/8380	1.61	2.78e-05	2.37e-03	80
GO:0031497	GO:0031497	chromatin assembly	47/3121	78/8380	1.62	2.88e-05	2.39e-03	78
GO:0007051	GO:0007051	spindle organization	39/3121	62/8380	1.69	3.46e-05	2.77e-03	62
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/3121	19/8380	2.26	3.58e-05	2.77e-03	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/3121	19/8380	2.26	3.58e-05	2.77e-03	19
GO:0000075	GO:0000075	cell cycle checkpoint	44/3121	73/8380	1.62	5.10e-05	3.82e-03	73
GO:0071824	GO:0071824	protein-DNA complex subunit organization	60/3121	107/8380	1.51	5.23e-05	3.82e-03	107
GO:0006334	GO:0006334	nucleosome assembly	43/3121	71/8380	1.63	5.26e-05	3.82e-03	71
GO:2001251	GO:2001251	negative regulation of chromosome organization	30/3121	45/8380	1.79	5.70e-05	4.07e-03	45
GO:0051784	GO:0051784	negative regulation of nuclear division	22/3121	30/8380	1.97	6.24e-05	4.39e-03	30
GO:0034728	GO:0034728	nucleosome organization	47/3121	80/8380	1.58	7.10e-05	4.92e-03	80
GO:0006399	GO:0006399	tRNA metabolic process	15/3121	18/8380	2.24	8.17e-05	5.27e-03	18
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/3121	18/8380	2.24	8.17e-05	5.27e-03	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/3121	18/8380	2.24	8.17e-05	5.27e-03	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/3121	18/8380	2.24	8.17e-05	5.27e-03	18
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	33/3121	52/8380	1.70	1.07e-04	6.70e-03	52
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	20/3121	27/8380	1.99	1.08e-04	6.70e-03	27
GO:0007080	GO:0007080	mitotic metaphase plate congression	13/3121	15/8380	2.33	1.18e-04	7.20e-03	15
GO:0006333	GO:0006333	chromatin assembly or disassembly	48/3121	84/8380	1.53	1.54e-04	9.08e-03	84
GO:0006275	GO:0006275	regulation of DNA replication	25/3121	37/8380	1.81	1.72e-04	9.63e-03	37
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	14/3121	17/8380	2.21	1.85e-04	9.63e-03	17
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	14/3121	17/8380	2.21	1.85e-04	9.63e-03	17
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	14/3121	17/8380	2.21	1.85e-04	9.63e-03	17
GO:0045132	GO:0045132	meiotic chromosome segregation	32/3121	51/8380	1.68	1.86e-04	9.63e-03	51
GO:0090502	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	18/3121	24/8380	2.01	1.87e-04	9.63e-03	24
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	28/3121	43/8380	1.75	1.87e-04	9.63e-03	43
GO:0000725	GO:0000725	recombinational repair	28/3121	43/8380	1.75	1.87e-04	9.63e-03	43
GO:0044786	GO:0044786	cell cycle DNA replication	15/3121	19/8380	2.12	2.54e-04	1.30e-02	19
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	12/3121	14/8380	2.30	2.77e-04	1.40e-02	14
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	43/3121	75/8380	1.54	3.03e-04	1.52e-02	75
GO:0007052	GO:0007052	mitotic spindle organization	28/3121	44/8380	1.71	3.32e-04	1.62e-02	44
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/3121	11/8380	2.44	3.71e-04	1.72e-02	11
GO:0044839	GO:0044839	cell cycle G2/M phase transition	46/3121	82/8380	1.51	3.75e-04	1.72e-02	82
GO:0034508	GO:0034508	centromere complex assembly	18/3121	25/8380	1.93	4.35e-04	1.94e-02	25
GO:0022613	GO:0022613	ribonucleoprotein complex biogenesis	34/3121	57/8380	1.60	4.71e-04	2.04e-02	57
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	24/3121	37/8380	1.74	5.85e-04	2.52e-02	37
GO:0031055	GO:0031055	chromatin remodeling at centromere	16/3121	22/8380	1.95	7.68e-04	3.05e-02	22
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	31/3121	52/8380	1.60	8.41e-04	3.28e-02	52
GO:0021522	GO:0021522	spinal cord motor neuron differentiation	17/3121	24/8380	1.90	8.54e-04	3.28e-02	24
GO:0043486	GO:0043486	histone exchange	17/3121	24/8380	1.90	8.54e-04	3.28e-02	24
GO:0061982	GO:0061982	meiosis I cell cycle process	38/3121	67/8380	1.52	8.90e-04	3.33e-02	67
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/3121	15/8380	2.15	9.11e-04	3.33e-02	15
GO:0008033	GO:0008033	tRNA processing	12/3121	15/8380	2.15	9.11e-04	3.33e-02	15
GO:0031577	GO:0031577	spindle checkpoint	12/3121	15/8380	2.15	9.11e-04	3.33e-02	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/3121	15/8380	2.15	9.11e-04	3.33e-02	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/3121	15/8380	2.15	9.11e-04	3.33e-02	15
GO:0021515	GO:0021515	cell differentiation in spinal cord	24/3121	38/8380	1.70	1.03e-03	3.71e-02	38
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	34/3121	59/8380	1.55	1.12e-03	4.00e-02	59

TP53_mis_down : 12 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0044782	GO:0044782	cilium organization	95/2917	151/8380	1.81	1.19e-12	5.81e-09	151
GO:0035082	GO:0035082	axoneme assembly	37/2917	43/8380	2.47	4.97e-12	1.21e-08	43
GO:0060271	GO:0060271	cilium assembly	88/2917	140/8380	1.81	8.76e-12	1.42e-08	140
GO:0003341	GO:0003341	cilium movement	36/2917	42/8380	2.46	1.24e-11	1.51e-08	42
GO:0001578	GO:0001578	microtubule bundle formation	42/2917	58/8380	2.08	5.26e-09	5.13e-06	58
GO:0070286	GO:0070286	axonemal dynein complex assembly	21/2917	23/8380	2.62	2.57e-08	2.09e-05	23
GO:0007018	GO:0007018	microtubule-based movement	69/2917	125/8380	1.59	2.09e-06	1.13e-03	125
GO:0044458	GO:0044458	motile cilium assembly	12/2917	13/8380	2.65	2.75e-05	1.22e-02	13
GO:0072329	GO:0072329	monocarboxylic acid catabolic process	41/2917	70/8380	1.68	3.88e-05	1.58e-02	70
GO:0001539	GO:0001539	cilium or flagellum-dependent cell motility	17/2917	22/8380	2.22	5.72e-05	1.86e-02	22
GO:0060285	GO:0060285	cilium-dependent cell motility	17/2917	22/8380	2.22	5.72e-05	1.86e-02	22
GO:0036158	GO:0036158	outer dynein arm assembly	11/2917	12/8380	2.63	7.35e-05	2.24e-02	12

CDH1_LOF_up : 409 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001944	GO:0001944	vasculature development	205/2185	465/8380	1.69	3.89e-18	7.60e-15	465
GO:0072358	GO:0072358	cardiovascular system development	207/2185	471/8380	1.69	4.04e-18	7.60e-15	471
GO:0001568	GO:0001568	blood vessel development	196/2185	448/8380	1.68	6.17e-17	7.74e-14	448
GO:0048514	GO:0048514	blood vessel morphogenesis	175/2185	404/8380	1.66	1.02e-14	9.63e-12	404
GO:0070848	GO:0070848	response to growth factor	176/2185	410/8380	1.65	2.37e-14	1.78e-11	410
GO:0071363	GO:0071363	cellular response to growth factor stimulus	168/2185	391/8380	1.65	8.72e-14	5.47e-11	391
GO:0001525	GO:0001525	angiogenesis	150/2185	342/8380	1.68	2.76e-13	1.48e-10	342
GO:0071559	GO:0071559	response to transforming growth factor beta	75/2185	139/8380	2.07	1.78e-12	7.85e-10	139
GO:0071560	GO:0071560	cellular response to transforming growth factor beta stimulus	73/2185	134/8380	2.09	1.88e-12	7.85e-10	134
GO:1901342	GO:1901342	regulation of vasculature development	102/2185	214/8380	1.83	5.33e-12	2.00e-09	214
GO:0045765	GO:0045765	regulation of angiogenesis	93/2185	191/8380	1.87	1.04e-11	3.57e-09	191
GO:0001501	GO:0001501	skeletal system development	148/2185	351/8380	1.62	1.62e-11	5.09e-09	351
GO:0007178	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	95/2185	202/8380	1.80	7.42e-11	2.15e-08	202
GO:0040013	GO:0040013	negative regulation of locomotion	94/2185	208/8380	1.73	1.33e-09	3.57e-07	208
GO:0090092	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	69/2185	140/8380	1.89	2.59e-09	6.51e-07	140
GO:0051271	GO:0051271	negative regulation of cellular component movement	92/2185	206/8380	1.71	4.18e-09	9.82e-07	206
GO:0007507	GO:0007507	heart development	133/2185	333/8380	1.53	1.19e-08	2.64e-06	333
GO:2000146	GO:2000146	negative regulation of cell motility	82/2185	181/8380	1.74	1.32e-08	2.75e-06	181
GO:0030336	GO:0030336	negative regulation of cell migration	79/2185	173/8380	1.75	1.57e-08	3.12e-06	173
GO:0016525	GO:0016525	negative regulation of angiogenesis	40/2185	69/8380	2.22	1.89e-08	3.55e-06	69
GO:0001667	GO:0001667	ameboidal-type cell migration	101/2185	239/8380	1.62	2.59e-08	4.64e-06	239
GO:0001503	GO:0001503	ossification	105/2185	252/8380	1.60	3.35e-08	5.72e-06	252
GO:0007179	GO:0007179	transforming growth factor beta receptor signaling pathway	50/2185	96/8380	2.00	4.23e-08	6.92e-06	96
GO:2000181	GO:2000181	negative regulation of blood vessel morphogenesis	40/2185	71/8380	2.16	5.68e-08	8.90e-06	71
GO:0019932	GO:0019932	second-messenger-mediated signaling	126/2185	320/8380	1.51	7.74e-08	1.16e-05	320
GO:0090287	GO:0090287	regulation of cellular response to growth factor stimulus	75/2185	167/8380	1.72	8.58e-08	1.24e-05	167
GO:1901343	GO:1901343	negative regulation of vasculature development	43/2185	80/8380	2.06	1.15e-07	1.55e-05	80
GO:0035265	GO:0035265	organ growth	59/2185	124/8380	1.82	1.80e-07	2.26e-05	124
GO:0030198	GO:0030198	extracellular matrix organization	114/2185	290/8380	1.51	3.60e-07	4.23e-05	290
GO:0018108	GO:0018108	peptidyl-tyrosine phosphorylation	100/2185	249/8380	1.54	5.91e-07	6.25e-05	249
GO:0018212	GO:0018212	peptidyl-tyrosine modification	100/2185	249/8380	1.54	5.91e-07	6.25e-05	249
GO:0007204	GO:0007204	positive regulation of cytosolic calcium ion concentration	94/2185	231/8380	1.56	6.42e-07	6.53e-05	231
GO:0090101	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	38/2185	71/8380	2.05	7.21e-07	7.14e-05	71
GO:1901654	GO:1901654	response to ketone	57/2185	125/8380	1.75	1.66e-06	1.60e-04	125
GO:0030278	GO:0030278	regulation of ossification	58/2185	128/8380	1.74	1.73e-06	1.63e-04	128
GO:0060070	GO:0060070	canonical Wnt signaling pathway	72/2185	170/8380	1.62	2.37e-06	2.02e-04	170
GO:0001659	GO:0001659	temperature homeostasis	52/2185	112/8380	1.78	2.42e-06	2.02e-04	112
GO:0010594	GO:0010594	regulation of endothelial cell migration	44/2185	90/8380	1.88	2.61e-06	2.13e-04	90
GO:1904018	GO:1904018	positive regulation of vasculature development	56/2185	124/8380	1.73	2.96e-06	2.27e-04	124
GO:0050678	GO:0050678	regulation of epithelial cell proliferation	88/2185	220/8380	1.53	3.40e-06	2.56e-04	220
GO:0010631	GO:0010631	epithelial cell migration	71/2185	169/8380	1.61	3.94e-06	2.85e-04	169
GO:0010632	GO:0010632	regulation of epithelial cell migration	57/2185	128/8380	1.71	4.16e-06	2.95e-04	128
GO:0001101	GO:0001101	response to acid chemical	88/2185	221/8380	1.53	4.23e-06	2.95e-04	221
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	60/2185	137/8380	1.68	4.53e-06	3.10e-04	137
GO:0097305	GO:0097305	response to alcohol	63/2185	146/8380	1.65	4.79e-06	3.15e-04	146
GO:0090132	GO:0090132	epithelium migration	71/2185	170/8380	1.60	5.06e-06	3.18e-04	170
GO:0030509	GO:0030509	BMP signaling pathway	45/2185	95/8380	1.82	5.90e-06	3.58e-04	95
GO:0060348	GO:0060348	bone development	61/2185	141/8380	1.66	6.11e-06	3.59e-04	141
GO:0043951	GO:0043951	negative regulation of cAMP-mediated signaling	13/2185	16/8380	3.12	6.15e-06	3.59e-04	16
GO:0030111	GO:0030111	regulation of Wnt signaling pathway	75/2185	183/8380	1.57	6.34e-06	3.59e-04	183
GO:0030510	GO:0030510	regulation of BMP signaling pathway	30/2185	55/8380	2.09	6.37e-06	3.59e-04	55
GO:0046677	GO:0046677	response to antibiotic	74/2185	180/8380	1.58	6.39e-06	3.59e-04	180
GO:0043542	GO:0043542	endothelial cell migration	54/2185	121/8380	1.71	6.85e-06	3.79e-04	121
GO:0045766	GO:0045766	positive regulation of angiogenesis	50/2185	110/8380	1.74	7.94e-06	4.33e-04	110
GO:0071772	GO:0071772	response to BMP	48/2185	105/8380	1.75	9.92e-06	5.04e-04	105
GO:0071773	GO:0071773	cellular response to BMP stimulus	48/2185	105/8380	1.75	9.92e-06	5.04e-04	105
GO:0090288	GO:0090288	negative regulation of cellular response to growth factor stimulus	43/2185	91/8380	1.81	1.02e-05	5.07e-04	91
GO:0019933	GO:0019933	cAMP-mediated signaling	59/2185	137/8380	1.65	1.02e-05	5.07e-04	137
GO:0033002	GO:0033002	muscle cell proliferation	58/2185	135/8380	1.65	1.33e-05	6.24e-04	135
GO:0019935	GO:0019935	cyclic-nucleotide-mediated signaling	66/2185	159/8380	1.59	1.37e-05	6.31e-04	159
GO:0106106	GO:0106106	cold-induced thermogenesis	43/2185	92/8380	1.79	1.44e-05	6.38e-04	92
GO:0120161	GO:0120161	regulation of cold-induced thermogenesis	43/2185	92/8380	1.79	1.44e-05	6.38e-04	92
GO:0061448	GO:0061448	connective tissue development	76/2185	190/8380	1.53	1.56e-05	6.75e-04	190
GO:0009612	GO:0009612	response to mechanical stimulus	59/2185	139/8380	1.63	1.75e-05	7.23e-04	139
GO:0048863	GO:0048863	stem cell differentiation	59/2185	139/8380	1.63	1.75e-05	7.23e-04	139
GO:0051216	GO:0051216	cartilage development	64/2185	154/8380	1.59	1.77e-05	7.23e-04	154
GO:0051354	GO:0051354	negative regulation of oxidoreductase activity	12/2185	15/8380	3.07	1.93e-05	7.66e-04	15
GO:0090130	GO:0090130	tissue migration	71/2185	176/8380	1.55	2.11e-05	8.17e-04	176
GO:0050731	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	57/2185	134/8380	1.63	2.24e-05	8.59e-04	134
GO:0071229	GO:0071229	cellular response to acid chemical	61/2185	146/8380	1.60	2.27e-05	8.64e-04	146
GO:0002040	GO:0002040	sprouting angiogenesis	37/2185	77/8380	1.84	2.63e-05	9.79e-04	77
GO:0000302	GO:0000302	response to reactive oxygen species	51/2185	117/8380	1.67	2.70e-05	9.96e-04	117
GO:1990845	GO:1990845	adaptive thermogenesis	44/2185	97/8380	1.74	2.92e-05	1.07e-03	97
GO:0030178	GO:0030178	negative regulation of Wnt signaling pathway	47/2185	106/8380	1.70	3.26e-05	1.17e-03	106
GO:0045444	GO:0045444	fat cell differentiation	58/2185	139/8380	1.60	3.75e-05	1.26e-03	139
GO:0051384	GO:0051384	response to glucocorticoid	46/2185	104/8380	1.70	4.25e-05	1.39e-03	104
GO:0031098	GO:0031098	stress-activated protein kinase signaling cascade	68/2185	170/8380	1.53	4.31e-05	1.40e-03	170
GO:0050730	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	65/2185	161/8380	1.55	4.51e-05	1.45e-03	161
GO:0051403	GO:0051403	stress-activated MAPK cascade	64/2185	158/8380	1.55	4.57e-05	1.46e-03	158
GO:0003007	GO:0003007	heart morphogenesis	70/2185	177/8380	1.52	5.15e-05	1.60e-03	177
GO:0030514	GO:0030514	negative regulation of BMP signaling pathway	20/2185	34/8380	2.26	5.33e-05	1.62e-03	34
GO:0046320	GO:0046320	regulation of fatty acid oxidation	13/2185	18/8380	2.77	5.44e-05	1.64e-03	18
GO:0010596	GO:0010596	negative regulation of endothelial cell migration	17/2185	27/8380	2.41	5.86e-05	1.74e-03	27
GO:0051489	GO:0051489	regulation of filopodium assembly	17/2185	27/8380	2.41	5.86e-05	1.74e-03	27
GO:0019722	GO:0019722	calcium-mediated signaling	61/2185	150/8380	1.56	5.96e-05	1.74e-03	150
GO:0090090	GO:0090090	negative regulation of canonical Wnt signaling pathway	39/2185	85/8380	1.76	5.97e-05	1.74e-03	85
GO:1903670	GO:1903670	regulation of sprouting angiogenesis	23/2185	42/8380	2.10	7.05e-05	1.99e-03	42
GO:0014074	GO:0014074	response to purine-containing compound	44/2185	100/8380	1.69	7.20e-05	2.00e-03	100
GO:0010463	GO:0010463	mesenchymal cell proliferation	21/2185	37/8380	2.18	7.21e-05	2.00e-03	37
GO:0017015	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	29/2185	58/8380	1.92	7.80e-05	2.11e-03	58
GO:0033135	GO:0033135	regulation of peptidyl-serine phosphorylation	33/2185	69/8380	1.83	7.96e-05	2.14e-03	69
GO:0046683	GO:0046683	response to organophosphorus	41/2185	92/8380	1.71	8.86e-05	2.32e-03	92
GO:0043368	GO:0043368	positive T cell selection	15/2185	23/8380	2.50	9.01e-05	2.34e-03	23
GO:0001763	GO:0001763	morphogenesis of a branching structure	59/2185	146/8380	1.55	9.66e-05	2.46e-03	146
GO:0060401	GO:0060401	cytosolic calcium ion transport	46/2185	107/8380	1.65	9.91e-05	2.50e-03	107
GO:0030323	GO:0030323	respiratory tube development	51/2185	122/8380	1.60	1.02e-04	2.56e-03	122
GO:0048511	GO:0048511	rhythmic process	64/2185	162/8380	1.52	1.10e-04	2.72e-03	162
GO:0014065	GO:0014065	phosphatidylinositol 3-kinase signaling	39/2185	87/8380	1.72	1.12e-04	2.73e-03	87
GO:1903844	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	29/2185	59/8380	1.89	1.16e-04	2.77e-03	59
GO:0045058	GO:0045058	T cell selection	19/2185	33/8380	2.21	1.23e-04	2.90e-03	33
GO:0051896	GO:0051896	regulation of protein kinase B signaling	55/2185	135/8380	1.56	1.27e-04	3.00e-03	135
GO:0045667	GO:0045667	regulation of osteoblast differentiation	35/2185	76/8380	1.77	1.28e-04	3.00e-03	76
GO:0010880	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	13/2185	19/8380	2.62	1.31e-04	3.02e-03	19
GO:0030324	GO:0030324	lung development	50/2185	120/8380	1.60	1.31e-04	3.02e-03	120
GO:0031960	GO:0031960	response to corticosteroid	49/2185	117/8380	1.61	1.31e-04	3.02e-03	117
GO:0006112	GO:0006112	energy reserve metabolic process	24/2185	46/8380	2.00	1.37e-04	3.10e-03	46
GO:0021537	GO:0021537	telencephalon development	61/2185	154/8380	1.52	1.45e-04	3.27e-03	154
GO:0051591	GO:0051591	response to cAMP	32/2185	68/8380	1.80	1.49e-04	3.32e-03	68
GO:0032872	GO:0032872	regulation of stress-activated MAPK cascade	56/2185	139/8380	1.55	1.58e-04	3.41e-03	139
GO:0010633	GO:0010633	negative regulation of epithelial cell migration	20/2185	36/8380	2.13	1.60e-04	3.41e-03	36
GO:0022029	GO:0022029	telencephalon cell migration	20/2185	36/8380	2.13	1.60e-04	3.41e-03	36
GO:0060541	GO:0060541	respiratory system development	55/2185	136/8380	1.55	1.61e-04	3.41e-03	136
GO:0061138	GO:0061138	morphogenesis of a branching epithelium	55/2185	136/8380	1.55	1.61e-04	3.41e-03	136
GO:0048659	GO:0048659	smooth muscle cell proliferation	42/2185	97/8380	1.66	1.62e-04	3.42e-03	97
GO:0001649	GO:0001649	osteoblast differentiation	54/2185	133/8380	1.56	1.63e-04	3.42e-03	133
GO:0048015	GO:0048015	phosphatidylinositol-mediated signaling	44/2185	103/8380	1.64	1.66e-04	3.47e-03	103
GO:0060402	GO:0060402	calcium ion transport into cytosol	45/2185	106/8380	1.63	1.67e-04	3.48e-03	106
GO:0008016	GO:0008016	regulation of heart contraction	63/2185	161/8380	1.50	1.72e-04	3.51e-03	161
GO:0050920	GO:0050920	regulation of chemotaxis	61/2185	155/8380	1.51	1.80e-04	3.65e-03	155
GO:0060419	GO:0060419	heart growth	30/2185	63/8380	1.83	1.83e-04	3.70e-03	63
GO:0018209	GO:0018209	peptidyl-serine modification	59/2185	149/8380	1.52	1.87e-04	3.73e-03	149
GO:0048762	GO:0048762	mesenchymal cell differentiation	57/2185	143/8380	1.53	1.95e-04	3.86e-03	143
GO:0070302	GO:0070302	regulation of stress-activated protein kinase signaling cascade	56/2185	140/8380	1.53	1.98e-04	3.88e-03	140
GO:0021885	GO:0021885	forebrain cell migration	21/2185	39/8380	2.07	2.00e-04	3.89e-03	39
GO:0071300	GO:0071300	cellular response to retinoic acid	27/2185	55/8380	1.88	2.02e-04	3.93e-03	55
GO:0036092	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	17/2185	29/8380	2.25	2.07e-04	3.98e-03	29
GO:0060420	GO:0060420	regulation of heart growth	24/2185	47/8380	1.96	2.11e-04	3.99e-03	47
GO:0051965	GO:0051965	positive regulation of synapse assembly	28/2185	58/8380	1.85	2.23e-04	4.19e-03	58
GO:0043491	GO:0043491	protein kinase B signaling	60/2185	153/8380	1.50	2.27e-04	4.24e-03	153
GO:0051968	GO:0051968	positive regulation of synaptic transmission, glutamatergic	14/2185	22/8380	2.44	2.29e-04	4.27e-03	22
GO:0046620	GO:0046620	regulation of organ growth	29/2185	61/8380	1.82	2.42e-04	4.49e-03	61
GO:0030512	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	20/2185	37/8380	2.07	2.64e-04	4.82e-03	37
GO:0048660	GO:0048660	regulation of smooth muscle cell proliferation	41/2185	96/8380	1.64	2.75e-04	4.98e-03	96
GO:0048017	GO:0048017	inositol lipid-mediated signaling	44/2185	105/8380	1.61	2.80e-04	5.03e-03	105
GO:0051491	GO:0051491	positive regulation of filopodium assembly	13/2185	20/8380	2.49	2.85e-04	5.06e-03	20
GO:0055017	GO:0055017	cardiac muscle tissue growth	27/2185	56/8380	1.85	2.95e-04	5.21e-03	56
GO:0010001	GO:0010001	glial cell differentiation	54/2185	136/8380	1.52	3.18e-04	5.59e-03	136
GO:0032526	GO:0032526	response to retinoic acid	35/2185	79/8380	1.70	3.26e-04	5.71e-03	79
GO:0031032	GO:0031032	actomyosin structure organization	47/2185	115/8380	1.57	3.52e-04	6.11e-03	115
GO:0042698	GO:0042698	ovulation cycle	25/2185	51/8380	1.88	3.55e-04	6.11e-03	51
GO:0051966	GO:0051966	regulation of synaptic transmission, glutamatergic	25/2185	51/8380	1.88	3.55e-04	6.11e-03	51
GO:0043534	GO:0043534	blood vessel endothelial cell migration	31/2185	68/8380	1.75	3.82e-04	6.48e-03	68
GO:0002673	GO:0002673	regulation of acute inflammatory response	33/2185	74/8380	1.71	4.14e-04	6.92e-03	74
GO:0035329	GO:0035329	hippo signaling	11/2185	16/8380	2.64	4.20e-04	6.97e-03	16
GO:1903845	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	20/2185	38/8380	2.02	4.21e-04	6.97e-03	38
GO:0033077	GO:0033077	T cell differentiation in thymus	23/2185	46/8380	1.92	4.23e-04	6.97e-03	46
GO:0002027	GO:0002027	regulation of heart rate	34/2185	77/8380	1.69	4.26e-04	7.00e-03	77
GO:0014808	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	14/2185	23/8380	2.33	4.46e-04	7.29e-03	23
GO:0002062	GO:0002062	chondrocyte differentiation	38/2185	89/8380	1.64	4.57e-04	7.41e-03	89
GO:0097553	GO:0097553	calcium ion transmembrane import into cytosol	41/2185	98/8380	1.60	4.63e-04	7.48e-03	98
GO:0110020	GO:0110020	regulation of actomyosin structure organization	24/2185	49/8380	1.88	4.71e-04	7.55e-03	49
GO:0009954	GO:0009954	proximal/distal pattern formation	16/2185	28/8380	2.19	4.75e-04	7.55e-03	28
GO:0060191	GO:0060191	regulation of lipase activity	29/2185	63/8380	1.77	4.79e-04	7.57e-03	63
GO:0055021	GO:0055021	regulation of cardiac muscle tissue growth	21/2185	41/8380	1.96	4.93e-04	7.73e-03	41
GO:0071385	GO:0071385	cellular response to glucocorticoid stimulus	21/2185	41/8380	1.96	4.93e-04	7.73e-03	41
GO:0001570	GO:0001570	vasculogenesis	25/2185	52/8380	1.84	5.17e-04	8.01e-03	52
GO:0002686	GO:0002686	negative regulation of leukocyte migration	19/2185	36/8380	2.02	5.59e-04	8.52e-03	36
GO:0035112	GO:0035112	genitalia morphogenesis	8/2185	10/8380	3.07	5.64e-04	8.52e-03	10
GO:0042308	GO:0042308	negative regulation of protein import into nucleus	8/2185	10/8380	3.07	5.64e-04	8.52e-03	10
GO:1904590	GO:1904590	negative regulation of protein import	8/2185	10/8380	3.07	5.64e-04	8.52e-03	10
GO:0071867	GO:0071867	response to monoamine	13/2185	21/8380	2.37	5.70e-04	8.54e-03	21
GO:0071869	GO:0071869	response to catecholamine	13/2185	21/8380	2.37	5.70e-04	8.54e-03	21
GO:0007189	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	43/2185	105/8380	1.57	5.87e-04	8.74e-03	105
GO:0010634	GO:0010634	positive regulation of epithelial cell migration	37/2185	87/8380	1.63	5.92e-04	8.74e-03	87
GO:0001508	GO:0001508	action potential	40/2185	96/8380	1.60	5.96e-04	8.74e-03	96
GO:0006661	GO:0006661	phosphatidylinositol biosynthetic process	27/2185	58/8380	1.79	5.97e-04	8.74e-03	58
GO:0014033	GO:0014033	neural crest cell differentiation	29/2185	64/8380	1.74	6.60e-04	9.52e-03	64
GO:0046854	GO:0046854	phosphatidylinositol phosphorylation	31/2185	70/8380	1.70	7.08e-04	1.02e-02	70
GO:0051897	GO:0051897	positive regulation of protein kinase B signaling	46/2185	115/8380	1.53	7.10e-04	1.02e-02	115
GO:0036336	GO:0036336	dendritic cell migration	12/2185	19/8380	2.42	7.23e-04	1.03e-02	19
GO:0072676	GO:0072676	lymphocyte migration	36/2185	85/8380	1.62	7.66e-04	1.08e-02	85
GO:0060421	GO:0060421	positive regulation of heart growth	16/2185	29/8380	2.12	8.06e-04	1.12e-02	29
GO:0120163	GO:0120163	negative regulation of cold-induced thermogenesis	16/2185	29/8380	2.12	8.06e-04	1.12e-02	29
GO:1903514	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	14/2185	24/8380	2.24	8.14e-04	1.13e-02	24
GO:0010595	GO:0010595	positive regulation of endothelial cell migration	27/2185	59/8380	1.76	8.30e-04	1.14e-02	59
GO:0003205	GO:0003205	cardiac chamber development	47/2185	119/8380	1.51	8.67e-04	1.18e-02	119
GO:0046622	GO:0046622	positive regulation of organ growth	19/2185	37/8380	1.97	8.71e-04	1.18e-02	37
GO:0071320	GO:0071320	cellular response to cAMP	19/2185	37/8380	1.97	8.71e-04	1.18e-02	37
GO:0048754	GO:0048754	branching morphogenesis of an epithelial tube	45/2185	113/8380	1.53	9.02e-04	1.22e-02	113
GO:0021782	GO:0021782	glial cell development	30/2185	68/8380	1.69	9.26e-04	1.25e-02	68
GO:0042133	GO:0042133	neurotransmitter metabolic process	41/2185	101/8380	1.56	9.60e-04	1.27e-02	101
GO:0050680	GO:0050680	negative regulation of epithelial cell proliferation	33/2185	77/8380	1.64	9.77e-04	1.28e-02	77
GO:0010863	GO:0010863	positive regulation of phospholipase C activity	17/2185	32/8380	2.04	9.87e-04	1.29e-02	32
GO:0001936	GO:0001936	regulation of endothelial cell proliferation	35/2185	83/8380	1.62	9.90e-04	1.29e-02	83
GO:0051963	GO:0051963	regulation of synapse assembly	37/2185	89/8380	1.59	9.90e-04	1.29e-02	89
GO:0014896	GO:0014896	muscle hypertrophy	25/2185	54/8380	1.78	1.04e-03	1.34e-02	54
GO:0060291	GO:0060291	long-term synaptic potentiation	25/2185	54/8380	1.78	1.04e-03	1.34e-02	54
GO:0007202	GO:0007202	activation of phospholipase C activity	13/2185	22/8380	2.27	1.06e-03	1.37e-02	22
GO:0055024	GO:0055024	regulation of cardiac muscle tissue development	26/2185	57/8380	1.75	1.09e-03	1.39e-02	57
GO:0071384	GO:0071384	cellular response to corticosteroid stimulus	21/2185	43/8380	1.87	1.10e-03	1.40e-02	43
GO:0010882	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	10/2185	15/8380	2.56	1.13e-03	1.42e-02	15
GO:0031102	GO:0031102	neuron projection regeneration	18/2185	35/8380	1.97	1.16e-03	1.44e-02	35
GO:0050919	GO:0050919	negative chemotaxis	18/2185	35/8380	1.97	1.16e-03	1.44e-02	35
GO:0098868	GO:0098868	bone growth	18/2185	35/8380	1.97	1.16e-03	1.44e-02	35
GO:0003151	GO:0003151	outflow tract morphogenesis	28/2185	63/8380	1.70	1.18e-03	1.46e-02	63
GO:0042542	GO:0042542	response to hydrogen peroxide	30/2185	69/8380	1.67	1.24e-03	1.52e-02	69
GO:0030177	GO:0030177	positive regulation of Wnt signaling pathway	31/2185	72/8380	1.65	1.25e-03	1.54e-02	72
GO:0046834	GO:0046834	lipid phosphorylation	33/2185	78/8380	1.62	1.28e-03	1.56e-02	78
GO:0010881	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	9/2185	13/8380	2.66	1.36e-03	1.65e-02	13
GO:0014897	GO:0014897	striated muscle hypertrophy	24/2185	52/8380	1.77	1.37e-03	1.65e-02	52
GO:0051341	GO:0051341	regulation of oxidoreductase activity	24/2185	52/8380	1.77	1.37e-03	1.65e-02	52
GO:0055023	GO:0055023	positive regulation of cardiac muscle tissue growth	14/2185	25/8380	2.15	1.41e-03	1.68e-02	25
GO:0070296	GO:0070296	sarcoplasmic reticulum calcium ion transport	14/2185	25/8380	2.15	1.41e-03	1.68e-02	25
GO:1903672	GO:1903672	positive regulation of sprouting angiogenesis	14/2185	25/8380	2.15	1.41e-03	1.68e-02	25
GO:0010812	GO:0010812	negative regulation of cell-substrate adhesion	20/2185	41/8380	1.87	1.47e-03	1.74e-02	41
GO:0035567	GO:0035567	non-canonical Wnt signaling pathway	27/2185	61/8380	1.70	1.54e-03	1.81e-02	61
GO:1900274	GO:1900274	regulation of phospholipase C activity	17/2185	33/8380	1.98	1.55e-03	1.81e-02	33
GO:0042476	GO:0042476	odontogenesis	39/2185	97/8380	1.54	1.56e-03	1.82e-02	97
GO:0120162	GO:0120162	positive regulation of cold-induced thermogenesis	28/2185	64/8380	1.68	1.58e-03	1.82e-02	64
GO:0001935	GO:0001935	endothelial cell proliferation	38/2185	94/8380	1.55	1.59e-03	1.82e-02	94
GO:0022612	GO:0022612	gland morphogenesis	38/2185	94/8380	1.55	1.59e-03	1.82e-02	94
GO:0031579	GO:0031579	membrane raft organization	8/2185	11/8380	2.79	1.59e-03	1.82e-02	11
GO:0046823	GO:0046823	negative regulation of nucleocytoplasmic transport	8/2185	11/8380	2.79	1.59e-03	1.82e-02	11
GO:1903421	GO:1903421	regulation of synaptic vesicle recycling	8/2185	11/8380	2.79	1.59e-03	1.82e-02	11
GO:0008589	GO:0008589	regulation of smoothened signaling pathway	21/2185	44/8380	1.83	1.60e-03	1.82e-02	44
GO:0014855	GO:0014855	striated muscle cell proliferation	21/2185	44/8380	1.83	1.60e-03	1.82e-02	44
GO:0072376	GO:0072376	protein activation cascade	30/2185	70/8380	1.64	1.63e-03	1.84e-02	70
GO:0003158	GO:0003158	endothelium development	31/2185	73/8380	1.63	1.64e-03	1.84e-02	73
GO:0007498	GO:0007498	mesoderm development	34/2185	82/8380	1.59	1.65e-03	1.84e-02	82
GO:0060395	GO:0060395	SMAD protein signal transduction	22/2185	47/8380	1.80	1.71e-03	1.90e-02	47
GO:0045668	GO:0045668	negative regulation of osteoblast differentiation	15/2185	28/8380	2.05	1.75e-03	1.92e-02	28
GO:0046323	GO:0046323	glucose import	15/2185	28/8380	2.05	1.75e-03	1.92e-02	28
GO:0050999	GO:0050999	regulation of nitric-oxide synthase activity	15/2185	28/8380	2.05	1.75e-03	1.92e-02	28
GO:0043949	GO:0043949	regulation of cAMP-mediated signaling	18/2185	36/8380	1.92	1.76e-03	1.92e-02	36
GO:0060425	GO:0060425	lung morphogenesis	18/2185	36/8380	1.92	1.76e-03	1.92e-02	36
GO:0071354	GO:0071354	cellular response to interleukin-6	11/2185	18/8380	2.34	1.79e-03	1.93e-02	18
GO:0071868	GO:0071868	cellular response to monoamine stimulus	11/2185	18/8380	2.34	1.79e-03	1.93e-02	18
GO:0071870	GO:0071870	cellular response to catecholamine stimulus	11/2185	18/8380	2.34	1.79e-03	1.93e-02	18
GO:0003300	GO:0003300	cardiac muscle hypertrophy	23/2185	50/8380	1.76	1.81e-03	1.93e-02	50
GO:0010517	GO:0010517	regulation of phospholipase activity	23/2185	50/8380	1.76	1.81e-03	1.93e-02	50
GO:0021954	GO:0021954	central nervous system neuron development	23/2185	50/8380	1.76	1.81e-03	1.93e-02	50
GO:0043535	GO:0043535	regulation of blood vessel endothelial cell migration	23/2185	50/8380	1.76	1.81e-03	1.93e-02	50
GO:1903426	GO:1903426	regulation of reactive oxygen species biosynthetic process	23/2185	50/8380	1.76	1.81e-03	1.93e-02	50
GO:0003382	GO:0003382	epithelial cell morphogenesis	13/2185	23/8380	2.17	1.86e-03	1.95e-02	23
GO:0005978	GO:0005978	glycogen biosynthetic process	13/2185	23/8380	2.17	1.86e-03	1.95e-02	23
GO:0009250	GO:0009250	glucan biosynthetic process	13/2185	23/8380	2.17	1.86e-03	1.95e-02	23
GO:0045923	GO:0045923	positive regulation of fatty acid metabolic process	13/2185	23/8380	2.17	1.86e-03	1.95e-02	23
GO:0090263	GO:0090263	positive regulation of canonical Wnt signaling pathway	24/2185	53/8380	1.74	1.90e-03	1.98e-02	53
GO:0040014	GO:0040014	regulation of multicellular organism growth	19/2185	39/8380	1.87	1.95e-03	2.02e-02	39
GO:1901655	GO:1901655	cellular response to ketone	26/2185	59/8380	1.69	2.02e-03	2.06e-02	59
GO:1904894	GO:1904894	positive regulation of STAT cascade	26/2185	59/8380	1.69	2.02e-03	2.06e-02	59
GO:0010171	GO:0010171	body morphogenesis	16/2185	31/8380	1.98	2.06e-03	2.07e-02	31
GO:0042306	GO:0042306	regulation of protein import into nucleus	16/2185	31/8380	1.98	2.06e-03	2.07e-02	31
GO:0050873	GO:0050873	brown fat cell differentiation	16/2185	31/8380	1.98	2.06e-03	2.07e-02	31
GO:0060043	GO:0060043	regulation of cardiac muscle cell proliferation	16/2185	31/8380	1.98	2.06e-03	2.07e-02	31
GO:1904589	GO:1904589	regulation of protein import	16/2185	31/8380	1.98	2.06e-03	2.07e-02	31
GO:0086065	GO:0086065	cell communication involved in cardiac conduction	20/2185	42/8380	1.83	2.12e-03	2.11e-02	42
GO:0034614	GO:0034614	cellular response to reactive oxygen species	32/2185	77/8380	1.59	2.13e-03	2.11e-02	77
GO:0035264	GO:0035264	multicellular organism growth	31/2185	74/8380	1.61	2.13e-03	2.11e-02	74
GO:0048640	GO:0048640	negative regulation of developmental growth	31/2185	74/8380	1.61	2.13e-03	2.11e-02	74
GO:0097366	GO:0097366	response to bronchodilator	17/2185	34/8380	1.92	2.35e-03	2.28e-02	34
GO:0043255	GO:0043255	regulation of carbohydrate biosynthetic process	22/2185	48/8380	1.76	2.40e-03	2.31e-02	48
GO:0010644	GO:0010644	cell communication by electrical coupling	12/2185	21/8380	2.19	2.46e-03	2.36e-02	21
GO:0010907	GO:0010907	positive regulation of glucose metabolic process	12/2185	21/8380	2.19	2.46e-03	2.36e-02	21
GO:0090317	GO:0090317	negative regulation of intracellular protein transport	12/2185	21/8380	2.19	2.46e-03	2.36e-02	21
GO:0030038	GO:0030038	contractile actin filament bundle assembly	23/2185	51/8380	1.73	2.50e-03	2.38e-02	51
GO:0033138	GO:0033138	positive regulation of peptidyl-serine phosphorylation	23/2185	51/8380	1.73	2.50e-03	2.38e-02	51
GO:0043149	GO:0043149	stress fiber assembly	23/2185	51/8380	1.73	2.50e-03	2.38e-02	51
GO:0006956	GO:0006956	complement activation	24/2185	54/8380	1.70	2.58e-03	2.43e-02	54
GO:0032231	GO:0032231	regulation of actin filament bundle assembly	24/2185	54/8380	1.70	2.58e-03	2.43e-02	54
GO:0002042	GO:0002042	cell migration involved in sprouting angiogenesis	18/2185	37/8380	1.87	2.60e-03	2.43e-02	37
GO:0046847	GO:0046847	filopodium assembly	18/2185	37/8380	1.87	2.60e-03	2.43e-02	37
GO:0045778	GO:0045778	positive regulation of ossification	25/2185	57/8380	1.68	2.65e-03	2.45e-02	57
GO:0046427	GO:0046427	positive regulation of JAK-STAT cascade	25/2185	57/8380	1.68	2.65e-03	2.45e-02	57
GO:0051208	GO:0051208	sequestering of calcium ion	34/2185	84/8380	1.55	2.66e-03	2.45e-02	84
GO:0060349	GO:0060349	bone morphogenesis	34/2185	84/8380	1.55	2.66e-03	2.45e-02	84
GO:1901019	GO:1901019	regulation of calcium ion transmembrane transporter activity	26/2185	60/8380	1.66	2.70e-03	2.47e-02	60
GO:0045446	GO:0045446	endothelial cell differentiation	27/2185	63/8380	1.64	2.73e-03	2.49e-02	63
GO:0060324	GO:0060324	face development	15/2185	29/8380	1.98	2.75e-03	2.50e-02	29
GO:0060389	GO:0060389	pathway-restricted SMAD protein phosphorylation	19/2185	40/8380	1.82	2.82e-03	2.56e-02	40
GO:0033137	GO:0033137	negative regulation of peptidyl-serine phosphorylation	9/2185	14/8380	2.47	2.93e-03	2.63e-02	14
GO:0051497	GO:0051497	negative regulation of stress fiber assembly	9/2185	14/8380	2.47	2.93e-03	2.63e-02	14
GO:0048678	GO:0048678	response to axon injury	20/2185	43/8380	1.78	3.01e-03	2.67e-02	43
GO:0007612	GO:0007612	learning	38/2185	97/8380	1.50	3.07e-03	2.71e-02	97
GO:0035051	GO:0035051	cardiocyte differentiation	38/2185	97/8380	1.50	3.07e-03	2.71e-02	97
GO:0034694	GO:0034694	response to prostaglandin	13/2185	24/8380	2.08	3.10e-03	2.73e-02	24
GO:0055025	GO:0055025	positive regulation of cardiac muscle tissue development	16/2185	32/8380	1.92	3.14e-03	2.76e-02	32
GO:0051017	GO:0051017	actin filament bundle assembly	37/2185	94/8380	1.51	3.15e-03	2.76e-02	94
GO:0042531	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	21/2185	46/8380	1.75	3.17e-03	2.76e-02	46
GO:0045123	GO:0045123	cellular extravasation	21/2185	46/8380	1.75	3.17e-03	2.76e-02	46
GO:0060193	GO:0060193	positive regulation of lipase activity	21/2185	46/8380	1.75	3.17e-03	2.76e-02	46
GO:0085029	GO:0085029	extracellular matrix assembly	11/2185	19/8380	2.22	3.25e-03	2.82e-02	19
GO:0042509	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	22/2185	49/8380	1.72	3.29e-03	2.84e-02	49
GO:0051209	GO:0051209	release of sequestered calcium ion into cytosol	33/2185	82/8380	1.54	3.40e-03	2.90e-02	82
GO:0051283	GO:0051283	negative regulation of sequestering of calcium ion	33/2185	82/8380	1.54	3.40e-03	2.90e-02	82
GO:0048708	GO:0048708	astrocyte differentiation	24/2185	55/8380	1.67	3.47e-03	2.92e-02	55
GO:0010676	GO:0010676	positive regulation of cellular carbohydrate metabolic process	17/2185	35/8380	1.86	3.47e-03	2.92e-02	35
GO:0032768	GO:0032768	regulation of monooxygenase activity	17/2185	35/8380	1.86	3.47e-03	2.92e-02	35
GO:0048806	GO:0048806	genitalia development	17/2185	35/8380	1.86	3.47e-03	2.92e-02	35
GO:1905207	GO:1905207	regulation of cardiocyte differentiation	17/2185	35/8380	1.86	3.47e-03	2.92e-02	35
GO:0003073	GO:0003073	regulation of systemic arterial blood pressure	29/2185	70/8380	1.59	3.56e-03	2.98e-02	70
GO:0010464	GO:0010464	regulation of mesenchymal cell proliferation	14/2185	27/8380	1.99	3.68e-03	3.00e-02	27
GO:0017145	GO:0017145	stem cell division	14/2185	27/8380	1.99	3.68e-03	3.00e-02	27
GO:0071604	GO:0071604	transforming growth factor beta production	14/2185	27/8380	1.99	3.68e-03	3.00e-02	27
GO:0002363	GO:0002363	alpha-beta T cell lineage commitment	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:0005979	GO:0005979	regulation of glycogen biosynthetic process	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:0010962	GO:0010962	regulation of glucan biosynthetic process	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:0046321	GO:0046321	positive regulation of fatty acid oxidation	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:0071871	GO:0071871	response to epinephrine	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:1904948	GO:1904948	midbrain dopaminergic neuron differentiation	8/2185	12/8380	2.56	3.69e-03	3.00e-02	12
GO:0010518	GO:0010518	positive regulation of phospholipase activity	19/2185	41/8380	1.78	3.99e-03	3.20e-02	41
GO:0048634	GO:0048634	regulation of muscle organ development	35/2185	89/8380	1.51	4.08e-03	3.26e-02	89
GO:1901861	GO:1901861	regulation of muscle tissue development	35/2185	89/8380	1.51	4.08e-03	3.26e-02	89
GO:0034260	GO:0034260	negative regulation of GTPase activity	12/2185	22/8380	2.09	4.14e-03	3.28e-02	22
GO:0060325	GO:0060325	face morphogenesis	12/2185	22/8380	2.09	4.14e-03	3.28e-02	22
GO:0061036	GO:0061036	positive regulation of cartilage development	12/2185	22/8380	2.09	4.14e-03	3.28e-02	22
GO:0070741	GO:0070741	response to interleukin-6	12/2185	22/8380	2.09	4.14e-03	3.28e-02	22
GO:0021915	GO:0021915	neural tube development	34/2185	86/8380	1.52	4.17e-03	3.28e-02	86
GO:0009880	GO:0009880	embryonic pattern specification	20/2185	44/8380	1.74	4.19e-03	3.28e-02	44
GO:0014910	GO:0014910	regulation of smooth muscle cell migration	20/2185	44/8380	1.74	4.19e-03	3.28e-02	44
GO:0051492	GO:0051492	regulation of stress fiber assembly	20/2185	44/8380	1.74	4.19e-03	3.28e-02	44
GO:0002688	GO:0002688	regulation of leukocyte chemotaxis	33/2185	83/8380	1.52	4.26e-03	3.31e-02	83
GO:0051282	GO:0051282	regulation of sequestering of calcium ion	33/2185	83/8380	1.52	4.26e-03	3.31e-02	83
GO:0061337	GO:0061337	cardiac conduction	33/2185	83/8380	1.52	4.26e-03	3.31e-02	83
GO:0097696	GO:0097696	STAT cascade	33/2185	83/8380	1.52	4.26e-03	3.31e-02	83
GO:0002407	GO:0002407	dendritic cell chemotaxis	10/2185	17/8380	2.26	4.29e-03	3.31e-02	17
GO:0014821	GO:0014821	phasic smooth muscle contraction	10/2185	17/8380	2.26	4.29e-03	3.31e-02	17
GO:0071875	GO:0071875	adrenergic receptor signaling pathway	10/2185	17/8380	2.26	4.29e-03	3.31e-02	17
GO:0014909	GO:0014909	smooth muscle cell migration	21/2185	47/8380	1.71	4.34e-03	3.32e-02	47
GO:0030279	GO:0030279	negative regulation of ossification	21/2185	47/8380	1.71	4.34e-03	3.32e-02	47
GO:0072678	GO:0072678	T cell migration	21/2185	47/8380	1.71	4.34e-03	3.32e-02	47
GO:0019233	GO:0019233	sensory perception of pain	32/2185	80/8380	1.53	4.34e-03	3.32e-02	80
GO:0007260	GO:0007260	tyrosine phosphorylation of STAT protein	22/2185	50/8380	1.69	4.46e-03	3.38e-02	50
GO:0003279	GO:0003279	cardiac septum development	30/2185	74/8380	1.55	4.49e-03	3.38e-02	74
GO:0001886	GO:0001886	endothelial cell morphogenesis	7/2185	10/8380	2.68	4.52e-03	3.38e-02	10
GO:0002295	GO:0002295	T-helper cell lineage commitment	7/2185	10/8380	2.68	4.52e-03	3.38e-02	10
GO:0035810	GO:0035810	positive regulation of urine volume	7/2185	10/8380	2.68	4.52e-03	3.38e-02	10
GO:0043116	GO:0043116	negative regulation of vascular permeability	7/2185	10/8380	2.68	4.52e-03	3.38e-02	10
GO:0014066	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	28/2185	68/8380	1.58	4.59e-03	3.39e-02	68
GO:0014812	GO:0014812	muscle cell migration	24/2185	56/8380	1.64	4.59e-03	3.39e-02	56
GO:0086001	GO:0086001	cardiac muscle cell action potential	24/2185	56/8380	1.64	4.59e-03	3.39e-02	56
GO:0060021	GO:0060021	roof of mouth development	27/2185	65/8380	1.59	4.62e-03	3.39e-02	65
GO:0090100	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	25/2185	59/8380	1.63	4.62e-03	3.39e-02	59
GO:0050848	GO:0050848	regulation of calcium-mediated signaling	26/2185	62/8380	1.61	4.63e-03	3.39e-02	62
GO:0003416	GO:0003416	endochondral bone growth	16/2185	33/8380	1.86	4.63e-03	3.39e-02	33
GO:0009187	GO:0009187	cyclic nucleotide metabolic process	16/2185	33/8380	1.86	4.63e-03	3.39e-02	33
GO:0033692	GO:0033692	cellular polysaccharide biosynthetic process	16/2185	33/8380	1.86	4.63e-03	3.39e-02	33
GO:0003413	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	13/2185	25/8380	1.99	4.94e-03	3.55e-02	25
GO:0006958	GO:0006958	complement activation, classical pathway	13/2185	25/8380	1.99	4.94e-03	3.55e-02	25
GO:0061756	GO:0061756	leukocyte adhesion to vascular endothelial cell	13/2185	25/8380	1.99	4.94e-03	3.55e-02	25
GO:0060038	GO:0060038	cardiac muscle cell proliferation	17/2185	36/8380	1.81	5.00e-03	3.57e-02	36
GO:0045661	GO:0045661	regulation of myoblast differentiation	18/2185	39/8380	1.77	5.30e-03	3.71e-02	39
GO:0048546	GO:0048546	digestive tract morphogenesis	18/2185	39/8380	1.77	5.30e-03	3.71e-02	39
GO:0010828	GO:0010828	positive regulation of glucose transmembrane transport	11/2185	20/8380	2.11	5.54e-03	3.81e-02	20
GO:0086012	GO:0086012	membrane depolarization during cardiac muscle cell action potential	11/2185	20/8380	2.11	5.54e-03	3.81e-02	20
GO:0003401	GO:0003401	axis elongation	14/2185	28/8380	1.92	5.62e-03	3.81e-02	28
GO:0031103	GO:0031103	axon regeneration	14/2185	28/8380	1.92	5.62e-03	3.81e-02	28
GO:0060976	GO:0060976	coronary vasculature development	14/2185	28/8380	1.92	5.62e-03	3.81e-02	28
GO:0071548	GO:0071548	response to dexamethasone	14/2185	28/8380	1.92	5.62e-03	3.81e-02	28
GO:0032232	GO:0032232	negative regulation of actin filament bundle assembly	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:0032332	GO:0032332	positive regulation of chondrocyte differentiation	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:0035812	GO:0035812	renal sodium excretion	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:0035813	GO:0035813	regulation of renal sodium excretion	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:0050995	GO:0050995	negative regulation of lipid catabolic process	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:1900115	GO:1900115	extracellular regulation of signal transduction	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:1900116	GO:1900116	extracellular negative regulation of signal transduction	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:1903671	GO:1903671	negative regulation of sprouting angiogenesis	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:2000050	GO:2000050	regulation of non-canonical Wnt signaling pathway	9/2185	15/8380	2.30	5.65e-03	3.81e-02	15
GO:1904892	GO:1904892	regulation of STAT cascade	30/2185	75/8380	1.53	5.65e-03	3.81e-02	75
GO:0035249	GO:0035249	synaptic transmission, glutamatergic	28/2185	69/8380	1.56	5.84e-03	3.92e-02	69
GO:0045913	GO:0045913	positive regulation of carbohydrate metabolic process	21/2185	48/8380	1.68	5.85e-03	3.92e-02	48
GO:0051899	GO:0051899	membrane depolarization	27/2185	66/8380	1.57	5.91e-03	3.95e-02	66
GO:0098727	GO:0098727	maintenance of cell number	27/2185	66/8380	1.57	5.91e-03	3.95e-02	66
GO:0060350	GO:0060350	endochondral bone morphogenesis	23/2185	54/8380	1.63	5.99e-03	3.97e-02	54
GO:1905954	GO:1905954	positive regulation of lipid localization	24/2185	57/8380	1.61	6.01e-03	3.97e-02	57
GO:0086010	GO:0086010	membrane depolarization during action potential	15/2185	31/8380	1.86	6.20e-03	4.06e-02	31
GO:1900076	GO:1900076	regulation of cellular response to insulin stimulus	15/2185	31/8380	1.86	6.20e-03	4.06e-02	31
GO:0001937	GO:0001937	negative regulation of endothelial cell proliferation	12/2185	23/8380	2.00	6.63e-03	4.30e-02	23
GO:0010837	GO:0010837	regulation of keratinocyte proliferation	12/2185	23/8380	2.00	6.63e-03	4.30e-02	23
GO:0045761	GO:0045761	regulation of adenylate cyclase activity	12/2185	23/8380	2.00	6.63e-03	4.30e-02	23
GO:0048009	GO:0048009	insulin-like growth factor receptor signaling pathway	12/2185	23/8380	2.00	6.63e-03	4.30e-02	23
GO:0005977	GO:0005977	glycogen metabolic process	16/2185	34/8380	1.80	6.67e-03	4.30e-02	34
GO:0061383	GO:0061383	trabecula morphogenesis	16/2185	34/8380	1.80	6.67e-03	4.30e-02	34
GO:0086091	GO:0086091	regulation of heart rate by cardiac conduction	16/2185	34/8380	1.80	6.67e-03	4.30e-02	34
GO:0071774	GO:0071774	response to fibroblast growth factor	31/2185	79/8380	1.50	6.89e-03	4.42e-02	79
GO:0035924	GO:0035924	cellular response to vascular endothelial growth factor stimulus	17/2185	37/8380	1.76	7.04e-03	4.51e-02	37
GO:0051145	GO:0051145	smooth muscle cell differentiation	18/2185	40/8380	1.73	7.33e-03	4.62e-02	40
GO:0007224	GO:0007224	smoothened signaling pathway	28/2185	70/8380	1.53	7.36e-03	4.62e-02	70
GO:0001867	GO:0001867	complement activation, lectin pathway	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0021542	GO:0021542	dentate gyrus development	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0043369	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0051450	GO:0051450	myoblast proliferation	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0060039	GO:0060039	pericardium development	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0060216	GO:0060216	definitive hemopoiesis	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0060390	GO:0060390	regulation of SMAD protein signal transduction	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0140058	GO:0140058	neuron projection arborization	8/2185	13/8380	2.36	7.40e-03	4.62e-02	13
GO:0001945	GO:0001945	lymph vessel development	10/2185	18/8380	2.13	7.42e-03	4.62e-02	18
GO:0042219	GO:0042219	cellular modified amino acid catabolic process	10/2185	18/8380	2.13	7.42e-03	4.62e-02	18
GO:0043537	GO:0043537	negative regulation of blood vessel endothelial cell migration	10/2185	18/8380	2.13	7.42e-03	4.62e-02	18
GO:0060314	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	10/2185	18/8380	2.13	7.42e-03	4.62e-02	18
GO:0046822	GO:0046822	regulation of nucleocytoplasmic transport	19/2185	43/8380	1.69	7.54e-03	4.68e-02	43
GO:0090049	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	13/2185	26/8380	1.92	7.55e-03	4.68e-02	26
GO:0019827	GO:0019827	stem cell population maintenance	26/2185	64/8380	1.56	7.60e-03	4.69e-02	64
GO:0048864	GO:0048864	stem cell development	25/2185	61/8380	1.57	7.70e-03	4.69e-02	61
GO:0070542	GO:0070542	response to fatty acid	25/2185	61/8380	1.57	7.70e-03	4.69e-02	61
GO:0014032	GO:0014032	neural crest cell development	24/2185	58/8380	1.59	7.77e-03	4.69e-02	58
GO:0043200	GO:0043200	response to amino acid	24/2185	58/8380	1.59	7.77e-03	4.69e-02	58
GO:0048661	GO:0048661	positive regulation of smooth muscle cell proliferation	24/2185	58/8380	1.59	7.77e-03	4.69e-02	58
GO:0060411	GO:0060411	cardiac septum morphogenesis	24/2185	58/8380	1.59	7.77e-03	4.69e-02	58
GO:0019217	GO:0019217	regulation of fatty acid metabolic process	21/2185	49/8380	1.64	7.77e-03	4.69e-02	49
GO:0061035	GO:0061035	regulation of cartilage development	21/2185	49/8380	1.64	7.77e-03	4.69e-02	49
GO:1904659	GO:1904659	glucose transmembrane transport	23/2185	55/8380	1.60	7.80e-03	4.69e-02	55
GO:0048247	GO:0048247	lymphocyte chemotaxis	22/2185	52/8380	1.62	7.81e-03	4.69e-02	52
GO:1990823	GO:1990823	response to leukemia inhibitory factor	22/2185	52/8380	1.62	7.81e-03	4.69e-02	52
GO:1990830	GO:1990830	cellular response to leukemia inhibitory factor	22/2185	52/8380	1.62	7.81e-03	4.69e-02	52
GO:2001057	GO:2001057	reactive nitrogen species metabolic process	22/2185	52/8380	1.62	7.81e-03	4.69e-02	52
GO:0008206	GO:0008206	bile acid metabolic process	14/2185	29/8380	1.85	8.30e-03	4.93e-02	29
GO:0032570	GO:0032570	response to progesterone	14/2185	29/8380	1.85	8.30e-03	4.93e-02	29
GO:0046626	GO:0046626	regulation of insulin receptor signaling pathway	14/2185	29/8380	1.85	8.30e-03	4.93e-02	29

CDH1_LOF_down : 270 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0051276	GO:0051276	chromosome organization	136/1061	406/8380	2.65	2.93e-29	1.17e-25	406
GO:0071103	GO:0071103	DNA conformation change	61/1061	120/8380	4.01	2.12e-24	4.22e-21	120
GO:0006323	GO:0006323	DNA packaging	50/1061	96/8380	4.11	8.24e-21	1.07e-17	96
GO:0048285	GO:0048285	organelle fission	80/1061	215/8380	2.94	1.23e-20	1.07e-17	215
GO:0000280	GO:0000280	nuclear division	76/1061	198/8380	3.03	1.35e-20	1.07e-17	198
GO:0006334	GO:0006334	nucleosome assembly	42/1061	71/8380	4.67	1.68e-20	1.11e-17	71
GO:0007059	GO:0007059	chromosome segregation	57/1061	126/8380	3.57	1.00e-19	5.70e-17	126
GO:0031497	GO:0031497	chromatin assembly	43/1061	78/8380	4.35	2.54e-19	1.26e-16	78
GO:1903047	GO:1903047	mitotic cell cycle process	98/1061	309/8380	2.50	2.93e-19	1.29e-16	309
GO:0000070	GO:0000070	mitotic sister chromatid segregation	37/1061	60/8380	4.87	4.44e-19	1.69e-16	60
GO:0065004	GO:0065004	protein-DNA complex assembly	48/1061	96/8380	3.95	4.68e-19	1.69e-16	96
GO:0140014	GO:0140014	mitotic nuclear division	55/1061	122/8380	3.56	5.47e-19	1.80e-16	122
GO:0000819	GO:0000819	sister chromatid segregation	42/1061	76/8380	4.36	5.90e-19	1.80e-16	76
GO:0051301	GO:0051301	cell division	86/1061	255/8380	2.66	6.74e-19	1.91e-16	255
GO:0034728	GO:0034728	nucleosome organization	43/1061	80/8380	4.25	9.33e-19	2.47e-16	80
GO:0098813	GO:0098813	nuclear chromosome segregation	51/1061	112/8380	3.60	6.31e-18	1.57e-15	112
GO:0006333	GO:0006333	chromatin assembly or disassembly	43/1061	84/8380	4.04	1.07e-17	2.50e-15	84
GO:0000278	GO:0000278	mitotic cell cycle	107/1061	370/8380	2.28	1.24e-17	2.75e-15	370
GO:0071824	GO:0071824	protein-DNA complex subunit organization	49/1061	107/8380	3.62	2.13e-17	4.46e-15	107
GO:0006259	GO:0006259	DNA metabolic process	97/1061	330/8380	2.32	1.43e-16	2.84e-14	330
GO:0006281	GO:0006281	DNA repair	55/1061	150/8380	2.90	3.19e-14	6.04e-12	150
GO:0032200	GO:0032200	telomere organization	27/1061	47/8380	4.54	3.36e-13	6.07e-11	47
GO:0006325	GO:0006325	chromatin organization	78/1061	270/8380	2.28	4.41e-13	7.62e-11	270
GO:0051983	GO:0051983	regulation of chromosome segregation	23/1061	40/8380	4.54	1.90e-11	3.15e-09	40
GO:0006302	GO:0006302	double-strand break repair	34/1061	80/8380	3.36	2.41e-11	3.84e-09	80
GO:0007051	GO:0007051	spindle organization	29/1061	62/8380	3.69	4.13e-11	6.32e-09	62
GO:0006342	GO:0006342	chromatin silencing	22/1061	38/8380	4.57	4.36e-11	6.43e-09	38
GO:0006261	GO:0006261	DNA-dependent DNA replication	27/1061	55/8380	3.88	4.77e-11	6.78e-09	55
GO:0010564	GO:0010564	regulation of cell cycle process	75/1061	279/8380	2.12	6.03e-11	8.27e-09	279
GO:0006974	GO:0006974	cellular response to DNA damage stimulus	72/1061	268/8380	2.12	1.53e-10	2.02e-08	268
GO:0034622	GO:0034622	cellular protein-containing complex assembly	97/1061	413/8380	1.86	3.69e-10	4.74e-08	413
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	25/1061	52/8380	3.80	4.43e-10	5.50e-08	52
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	14/1061	18/8380	6.14	4.70e-10	5.50e-08	18
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	14/1061	18/8380	6.14	4.70e-10	5.50e-08	18
GO:0044770	GO:0044770	cell cycle phase transition	59/1061	206/8380	2.26	5.01e-10	5.70e-08	206
GO:0033045	GO:0033045	regulation of sister chromatid segregation	19/1061	32/8380	4.69	5.20e-10	5.74e-08	32
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	15/1061	21/8380	5.64	8.12e-10	8.50e-08	21
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	15/1061	21/8380	5.64	8.12e-10	8.50e-08	21
GO:0000183	GO:0000183	chromatin silencing at rDNA	14/1061	19/8380	5.82	1.58e-09	1.57e-07	19
GO:0044772	GO:0044772	mitotic cell cycle phase transition	55/1061	191/8380	2.27	1.58e-09	1.57e-07	191
GO:0000079	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	24/1061	51/8380	3.72	1.72e-09	1.67e-07	51
GO:0006260	GO:0006260	DNA replication	35/1061	96/8380	2.88	1.89e-09	1.75e-07	96
GO:0007052	GO:0007052	mitotic spindle organization	22/1061	44/8380	3.95	1.94e-09	1.75e-07	44
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	22/1061	44/8380	3.95	1.94e-09	1.75e-07	44
GO:0006310	GO:0006310	DNA recombination	36/1061	101/8380	2.82	2.27e-09	2.00e-07	101
GO:0007346	GO:0007346	regulation of mitotic cell cycle	63/1061	237/8380	2.10	3.52e-09	3.04e-07	237
GO:0007088	GO:0007088	regulation of mitotic nuclear division	33/1061	90/8380	2.90	4.64e-09	3.77e-07	90
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	14/1061	20/8380	5.53	4.65e-09	3.77e-07	20
GO:0061641	GO:0061641	CENP-A containing chromatin organization	14/1061	20/8380	5.53	4.65e-09	3.77e-07	20
GO:0000723	GO:0000723	telomere maintenance	20/1061	39/8380	4.05	6.02e-09	4.79e-07	39
GO:0051726	GO:0051726	regulation of cell cycle	102/1061	465/8380	1.73	6.92e-09	5.40e-07	465
GO:1904029	GO:1904029	regulation of cyclin-dependent protein kinase activity	24/1061	54/8380	3.51	7.20e-09	5.51e-07	54
GO:1903046	GO:1903046	meiotic cell cycle process	36/1061	105/8380	2.71	7.53e-09	5.65e-07	105
GO:0045787	GO:0045787	positive regulation of cell cycle	53/1061	189/8380	2.21	8.71e-09	6.42e-07	189
GO:0051321	GO:0051321	meiotic cell cycle	41/1061	130/8380	2.49	1.13e-08	8.16e-07	130
GO:0060968	GO:0060968	regulation of gene silencing	22/1061	49/8380	3.55	2.44e-08	1.73e-06	49
GO:0034508	GO:0034508	centromere complex assembly	15/1061	25/8380	4.74	2.97e-08	2.05e-06	25
GO:0031055	GO:0031055	chromatin remodeling at centromere	14/1061	22/8380	5.03	2.99e-08	2.05e-06	22
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	11/1061	14/8380	6.21	3.23e-08	2.18e-06	14
GO:0051225	GO:0051225	spindle assembly	18/1061	35/8380	4.06	3.31e-08	2.20e-06	35
GO:0051304	GO:0051304	chromosome separation	19/1061	39/8380	3.85	4.29e-08	2.79e-06	39
GO:1901987	GO:1901987	regulation of cell cycle phase transition	43/1061	146/8380	2.33	4.77e-08	3.06e-06	146
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	15/1061	26/8380	4.56	6.21e-08	3.69e-06	26
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	15/1061	26/8380	4.56	6.21e-08	3.69e-06	26
GO:0050000	GO:0050000	chromosome localization	15/1061	26/8380	4.56	6.21e-08	3.69e-06	26
GO:0051303	GO:0051303	establishment of chromosome localization	15/1061	26/8380	4.56	6.21e-08	3.69e-06	26
GO:0051306	GO:0051306	mitotic sister chromatid separation	15/1061	26/8380	4.56	6.21e-08	3.69e-06	26
GO:0051310	GO:0051310	metaphase plate congression	13/1061	20/8380	5.13	6.58e-08	3.85e-06	20
GO:0140013	GO:0140013	meiotic nuclear division	33/1061	99/8380	2.63	6.92e-08	3.99e-06	99
GO:0007080	GO:0007080	mitotic metaphase plate congression	11/1061	15/8380	5.79	1.07e-07	6.10e-06	15
GO:0051783	GO:0051783	regulation of nuclear division	33/1061	101/8380	2.58	1.19e-07	6.67e-06	101
GO:1905818	GO:1905818	regulation of chromosome separation	15/1061	27/8380	4.39	1.23e-07	6.82e-06	27
GO:2001251	GO:2001251	negative regulation of chromosome organization	20/1061	45/8380	3.51	1.30e-07	7.11e-06	45
GO:0043486	GO:0043486	histone exchange	14/1061	24/8380	4.61	1.43e-07	7.70e-06	24
GO:0009812	GO:0009812	flavonoid metabolic process	10/1061	13/8380	6.08	2.03e-07	1.08e-05	13
GO:0061982	GO:0061982	meiosis I cell cycle process	25/1061	67/8380	2.95	2.33e-07	1.22e-05	67
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	14/1061	25/8380	4.42	2.88e-07	1.49e-05	25
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	19/1061	43/8380	3.49	3.02e-07	1.52e-05	43
GO:0000725	GO:0000725	recombinational repair	19/1061	43/8380	3.49	3.02e-07	1.52e-05	43
GO:0060337	GO:0060337	type I interferon signaling pathway	21/1061	51/8380	3.25	3.11e-07	1.53e-05	51
GO:0071357	GO:0071357	cellular response to type I interferon	21/1061	51/8380	3.25	3.11e-07	1.53e-05	51
GO:0052697	GO:0052697	xenobiotic glucuronidation	9/1061	11/8380	6.46	3.51e-07	1.70e-05	11
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	17/1061	36/8380	3.73	3.94e-07	1.89e-05	36
GO:0000910	GO:0000910	cytokinesis	23/1061	60/8380	3.03	4.02e-07	1.90e-05	60
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	38/1061	131/8380	2.29	4.41e-07	2.07e-05	131
GO:0034340	GO:0034340	response to type I interferon	21/1061	52/8380	3.19	4.60e-07	2.13e-05	52
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	14/1061	26/8380	4.25	5.51e-07	2.46e-05	26
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	14/1061	26/8380	4.25	5.51e-07	2.46e-05	26
GO:0051290	GO:0051290	protein heterotetramerization	14/1061	26/8380	4.25	5.51e-07	2.46e-05	26
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	23/1061	61/8380	2.98	5.69e-07	2.51e-05	61
GO:0090068	GO:0090068	positive regulation of cell cycle process	38/1061	133/8380	2.26	6.73e-07	2.94e-05	133
GO:0070647	GO:0070647	protein modification by small protein conjugation or removal	68/1061	300/8380	1.79	7.31e-07	3.16e-05	300
GO:0030261	GO:0030261	chromosome condensation	12/1061	20/8380	4.74	7.59e-07	3.25e-05	20
GO:0033044	GO:0033044	regulation of chromosome organization	32/1061	104/8380	2.43	8.52e-07	3.61e-05	104
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	13/1061	24/8380	4.28	1.30e-06	5.43e-05	24
GO:0000075	GO:0000075	cell cycle checkpoint	25/1061	73/8380	2.70	1.52e-06	6.25e-05	73
GO:0007127	GO:0007127	meiosis I	23/1061	64/8380	2.84	1.52e-06	6.25e-05	64
GO:0090307	GO:0090307	mitotic spindle assembly	12/1061	21/8380	4.51	1.57e-06	6.36e-05	21
GO:0031424	GO:0031424	keratinization	33/1061	113/8380	2.31	2.13e-06	8.56e-05	113
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	13/1061	25/8380	4.11	2.39e-06	9.50e-05	25
GO:0070268	GO:0070268	cornification	29/1061	95/8380	2.41	3.30e-06	1.29e-04	95
GO:0000226	GO:0000226	microtubule cytoskeleton organization	58/1061	253/8380	1.81	3.31e-06	1.29e-04	253
GO:0006270	GO:0006270	DNA replication initiation	10/1061	16/8380	4.94	3.95e-06	1.53e-04	16
GO:0032446	GO:0032446	protein modification by small protein conjugation	57/1061	251/8380	1.79	5.48e-06	2.10e-04	251
GO:0098542	GO:0098542	defense response to other organism	58/1061	259/8380	1.77	7.18e-06	2.65e-04	259
GO:0006063	GO:0006063	uronic acid metabolic process	11/1061	20/8380	4.34	7.19e-06	2.65e-04	20
GO:0019585	GO:0019585	glucuronate metabolic process	11/1061	20/8380	4.34	7.19e-06	2.65e-04	20
GO:0032392	GO:0032392	DNA geometric change	13/1061	27/8380	3.80	7.21e-06	2.65e-04	27
GO:0051984	GO:0051984	positive regulation of chromosome segregation	8/1061	11/8380	5.74	7.46e-06	2.72e-04	11
GO:0051607	GO:0051607	defense response to virus	32/1061	115/8380	2.20	9.33e-06	3.37e-04	115
GO:0000726	GO:0000726	non-recombinational repair	12/1061	24/8380	3.95	9.99e-06	3.58e-04	24
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	18/1061	48/8380	2.96	1.05e-05	3.74e-04	48
GO:0016567	GO:0016567	protein ubiquitination	54/1061	239/8380	1.78	1.13e-05	3.98e-04	239
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	16/1061	40/8380	3.16	1.25e-05	4.36e-04	40
GO:0002385	GO:0002385	mucosal immune response	11/1061	21/8380	4.14	1.34e-05	4.63e-04	21
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	10/1061	18/8380	4.39	1.70e-05	5.64e-04	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	10/1061	18/8380	4.39	1.70e-05	5.64e-04	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	10/1061	18/8380	4.39	1.70e-05	5.64e-04	18
GO:0007131	GO:0007131	reciprocal meiotic recombination	12/1061	25/8380	3.79	1.70e-05	5.64e-04	25
GO:0035825	GO:0035825	homologous recombination	12/1061	25/8380	3.79	1.70e-05	5.64e-04	25
GO:0000281	GO:0000281	mitotic cytokinesis	13/1061	29/8380	3.54	1.91e-05	6.28e-04	29
GO:0044843	GO:0044843	cell cycle G1/S phase transition	30/1061	109/8380	2.17	2.22e-05	7.25e-04	109
GO:0006303	GO:0006303	double-strand break repair via nonhomologous end joining	11/1061	22/8380	3.95	2.37e-05	7.61e-04	22
GO:0032508	GO:0032508	DNA duplex unwinding	11/1061	22/8380	3.95	2.37e-05	7.61e-04	22
GO:0060147	GO:0060147	regulation of posttranscriptional gene silencing	15/1061	38/8380	3.12	2.82e-05	8.90e-04	38
GO:0060966	GO:0060966	regulation of gene silencing by RNA	15/1061	38/8380	3.12	2.82e-05	8.90e-04	38
GO:0016032	GO:0016032	viral process	56/1061	259/8380	1.71	3.03e-05	9.49e-04	259
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	23/1061	75/8380	2.42	3.11e-05	9.65e-04	75
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	10/1061	19/8380	4.16	3.18e-05	9.73e-04	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	10/1061	19/8380	4.16	3.18e-05	9.73e-04	19
GO:0016458	GO:0016458	gene silencing	24/1061	81/8380	2.34	3.95e-05	1.20e-03	81
GO:0002251	GO:0002251	organ or tissue specific immune response	11/1061	23/8380	3.78	4.03e-05	1.20e-03	23
GO:0007062	GO:0007062	sister chromatid cohesion	11/1061	23/8380	3.78	4.03e-05	1.20e-03	23
GO:1903901	GO:1903901	negative regulation of viral life cycle	15/1061	39/8380	3.04	4.05e-05	1.20e-03	39
GO:0002227	GO:0002227	innate immune response in mucosa	8/1061	13/8380	4.86	4.60e-05	1.35e-03	13
GO:0036297	GO:0036297	interstrand cross-link repair	8/1061	13/8380	4.86	4.60e-05	1.35e-03	13
GO:0044839	GO:0044839	cell cycle G2/M phase transition	24/1061	82/8380	2.31	4.93e-05	1.43e-03	82
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	23/1061	77/8380	2.36	4.94e-05	1.43e-03	77
GO:0070507	GO:0070507	regulation of microtubule cytoskeleton organization	25/1061	88/8380	2.24	5.97e-05	1.71e-03	88
GO:0044403	GO:0044403	symbiont process	60/1061	290/8380	1.63	6.24e-05	1.77e-03	290
GO:0060964	GO:0060964	regulation of gene silencing by miRNA	14/1061	36/8380	3.07	6.33e-05	1.79e-03	36
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	9/1061	17/8380	4.18	7.59e-05	2.07e-03	17
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	9/1061	17/8380	4.18	7.59e-05	2.07e-03	17
GO:0052695	GO:0052695	cellular glucuronidation	9/1061	17/8380	4.18	7.59e-05	2.07e-03	17
GO:0090224	GO:0090224	regulation of spindle organization	9/1061	17/8380	4.18	7.59e-05	2.07e-03	17
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	9/1061	17/8380	4.18	7.59e-05	2.07e-03	17
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	22/1061	74/8380	2.35	7.76e-05	2.10e-03	74
GO:0045652	GO:0045652	regulation of megakaryocyte differentiation	14/1061	37/8380	2.99	9.02e-05	2.42e-03	37
GO:0044419	GO:0044419	interspecies interaction between organisms	64/1061	319/8380	1.58	9.39e-05	2.51e-03	319
GO:1904031	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	8/1061	14/8380	4.51	9.54e-05	2.53e-03	14
GO:0031935	GO:0031935	regulation of chromatin silencing	7/1061	11/8380	5.03	1.06e-04	2.78e-03	11
GO:0045737	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	7/1061	11/8380	5.03	1.06e-04	2.78e-03	11
GO:0051052	GO:0051052	regulation of DNA metabolic process	35/1061	146/8380	1.89	1.13e-04	2.94e-03	146
GO:0044265	GO:0044265	cellular macromolecule catabolic process	61/1061	303/8380	1.59	1.23e-04	3.19e-03	303
GO:0048525	GO:0048525	negative regulation of viral process	16/1061	47/8380	2.69	1.26e-04	3.23e-03	47
GO:0007017	GO:0007017	microtubule-based process	66/1061	335/8380	1.56	1.29e-04	3.29e-03	335
GO:0007143	GO:0007143	female meiotic nuclear division	9/1061	18/8380	3.95	1.35e-04	3.41e-03	18
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	17/1061	52/8380	2.58	1.38e-04	3.48e-03	52
GO:0034502	GO:0034502	protein localization to chromosome	10/1061	22/8380	3.59	1.55e-04	3.86e-03	22
GO:0044380	GO:0044380	protein localization to cytoskeleton	10/1061	22/8380	3.59	1.55e-04	3.86e-03	22
GO:0005996	GO:0005996	monosaccharide metabolic process	36/1061	154/8380	1.85	1.57e-04	3.87e-03	154
GO:0044257	GO:0044257	cellular protein catabolic process	45/1061	208/8380	1.71	1.77e-04	4.33e-03	208
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	8/1061	15/8380	4.21	1.82e-04	4.33e-03	15
GO:0031577	GO:0031577	spindle checkpoint	8/1061	15/8380	4.21	1.82e-04	4.33e-03	15
GO:0060236	GO:0060236	regulation of mitotic spindle organization	8/1061	15/8380	4.21	1.82e-04	4.33e-03	15
GO:0071173	GO:0071173	spindle assembly checkpoint	8/1061	15/8380	4.21	1.82e-04	4.33e-03	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	8/1061	15/8380	4.21	1.82e-04	4.33e-03	15
GO:0010948	GO:0010948	negative regulation of cell cycle process	28/1061	110/8380	2.01	1.83e-04	4.33e-03	110
GO:0006753	GO:0006753	nucleoside phosphate metabolic process	59/1061	295/8380	1.58	1.91e-04	4.50e-03	295
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	26/1061	100/8380	2.05	2.13e-04	4.99e-03	100
GO:0045071	GO:0045071	negative regulation of viral genome replication	12/1061	31/8380	3.06	2.23e-04	5.14e-03	31
GO:0051262	GO:0051262	protein tetramerization	22/1061	79/8380	2.20	2.24e-04	5.14e-03	79
GO:0090305	GO:0090305	nucleic acid phosphodiester bond hydrolysis	22/1061	79/8380	2.20	2.24e-04	5.14e-03	79
GO:0051443	GO:0051443	positive regulation of ubiquitin-protein transferase activity	7/1061	12/8380	4.61	2.27e-04	5.17e-03	12
GO:0044786	GO:0044786	cell cycle DNA replication	9/1061	19/8380	3.74	2.27e-04	5.17e-03	19
GO:0010498	GO:0010498	proteasomal protein catabolic process	29/1061	117/8380	1.96	2.32e-04	5.25e-03	117
GO:0032886	GO:0032886	regulation of microtubule-based process	27/1061	106/8380	2.01	2.34e-04	5.27e-03	106
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	18/1061	59/8380	2.41	2.38e-04	5.33e-03	59
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	28/1061	112/8380	1.97	2.54e-04	5.64e-03	112
GO:0045786	GO:0045786	negative regulation of cell cycle	49/1061	236/8380	1.64	2.65e-04	5.85e-03	236
GO:0006695	GO:0006695	cholesterol biosynthetic process	13/1061	36/8380	2.85	2.77e-04	6.05e-03	36
GO:1902653	GO:1902653	secondary alcohol biosynthetic process	13/1061	36/8380	2.85	2.77e-04	6.05e-03	36
GO:0031570	GO:0031570	DNA integrity checkpoint	16/1061	50/8380	2.53	2.85e-04	6.20e-03	50
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	20/1061	70/8380	2.26	2.94e-04	6.35e-03	70
GO:0033260	GO:0033260	nuclear DNA replication	8/1061	16/8380	3.95	3.23e-04	6.94e-03	16
GO:0051186	GO:0051186	cofactor metabolic process	57/1061	288/8380	1.56	3.24e-04	6.94e-03	288
GO:0040029	GO:0040029	regulation of gene expression, epigenetic	24/1061	92/8380	2.06	3.49e-04	7.43e-03	92
GO:0045132	GO:0045132	meiotic chromosome segregation	16/1061	51/8380	2.48	3.68e-04	7.78e-03	51
GO:0051291	GO:0051291	protein heterooligomerization	19/1061	66/8380	2.27	3.72e-04	7.82e-03	66
GO:0009117	GO:0009117	nucleotide metabolic process	57/1061	290/8380	1.55	3.90e-04	8.16e-03	290
GO:0030216	GO:0030216	keratinocyte differentiation	36/1061	161/8380	1.77	3.96e-04	8.24e-03	161
GO:0006338	GO:0006338	chromatin remodeling	17/1061	57/8380	2.36	4.74e-04	9.83e-03	57
GO:0051603	GO:0051603	proteolysis involved in cellular protein catabolic process	40/1061	187/8380	1.69	5.07e-04	1.05e-02	187
GO:0031936	GO:0031936	negative regulation of chromatin silencing	6/1061	10/8380	4.74	5.42e-04	1.11e-02	10
GO:0045069	GO:0045069	regulation of viral genome replication	14/1061	43/8380	2.57	5.56e-04	1.13e-02	43
GO:0006977	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9/1061	21/8380	3.38	5.71e-04	1.15e-02	21
GO:1903900	GO:1903900	regulation of viral life cycle	18/1061	63/8380	2.26	5.81e-04	1.17e-02	63
GO:0044270	GO:0044270	cellular nitrogen compound catabolic process	46/1061	227/8380	1.60	7.05e-04	1.41e-02	227
GO:0007005	GO:0007005	mitochondrion organization	32/1061	142/8380	1.78	7.07e-04	1.41e-02	142
GO:0045333	GO:0045333	cellular respiration	14/1061	44/8380	2.51	7.22e-04	1.43e-02	44
GO:0016441	GO:0016441	posttranscriptional gene silencing	15/1061	49/8380	2.42	7.44e-04	1.46e-02	49
GO:0035194	GO:0035194	posttranscriptional gene silencing by RNA	15/1061	49/8380	2.42	7.44e-04	1.46e-02	49
GO:0022904	GO:0022904	respiratory electron transport chain	10/1061	26/8380	3.04	7.92e-04	1.54e-02	26
GO:0032465	GO:0032465	regulation of cytokinesis	12/1061	35/8380	2.71	8.13e-04	1.58e-02	35
GO:0009615	GO:0009615	response to virus	35/1061	161/8380	1.72	8.17e-04	1.58e-02	161
GO:1902600	GO:1902600	proton transmembrane transport	19/1061	70/8380	2.14	8.31e-04	1.60e-02	70
GO:0043161	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	25/1061	103/8380	1.92	8.53e-04	1.60e-02	103
GO:0072413	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	9/1061	22/8380	3.23	8.59e-04	1.60e-02	22
GO:0072431	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	9/1061	22/8380	3.23	8.59e-04	1.60e-02	22
GO:1902400	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	9/1061	22/8380	3.23	8.59e-04	1.60e-02	22
GO:1902402	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	9/1061	22/8380	3.23	8.59e-04	1.60e-02	22
GO:1902403	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	9/1061	22/8380	3.23	8.59e-04	1.60e-02	22
GO:0010971	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	8/1061	18/8380	3.51	8.70e-04	1.60e-02	18
GO:0045910	GO:0045910	negative regulation of DNA recombination	8/1061	18/8380	3.51	8.70e-04	1.60e-02	18
GO:0051438	GO:0051438	regulation of ubiquitin-protein transferase activity	8/1061	18/8380	3.51	8.70e-04	1.60e-02	18
GO:0097193	GO:0097193	intrinsic apoptotic signaling pathway	30/1061	132/8380	1.80	8.84e-04	1.62e-02	132
GO:0016126	GO:0016126	sterol biosynthetic process	13/1061	40/8380	2.57	8.87e-04	1.62e-02	40
GO:0030219	GO:0030219	megakaryocyte differentiation	14/1061	45/8380	2.46	9.28e-04	1.68e-02	45
GO:0035195	GO:0035195	gene silencing by miRNA	14/1061	45/8380	2.46	9.28e-04	1.68e-02	45
GO:0009913	GO:0009913	epidermal cell differentiation	40/1061	193/8380	1.64	9.76e-04	1.76e-02	193
GO:0006998	GO:0006998	nuclear envelope organization	6/1061	11/8380	4.31	1.06e-03	1.90e-02	11
GO:0046700	GO:0046700	heterocycle catabolic process	45/1061	225/8380	1.58	1.07e-03	1.90e-02	225
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	10/1061	27/8380	2.93	1.12e-03	1.96e-02	27
GO:0072401	GO:0072401	signal transduction involved in DNA integrity checkpoint	10/1061	27/8380	2.93	1.12e-03	1.96e-02	27
GO:0072422	GO:0072422	signal transduction involved in DNA damage checkpoint	10/1061	27/8380	2.93	1.12e-03	1.96e-02	27
GO:2000779	GO:2000779	regulation of double-strand break repair	10/1061	27/8380	2.93	1.12e-03	1.96e-02	27
GO:0031571	GO:0031571	mitotic G1 DNA damage checkpoint	9/1061	23/8380	3.09	1.25e-03	2.17e-02	23
GO:0044783	GO:0044783	G1 DNA damage checkpoint	9/1061	23/8380	3.09	1.25e-03	2.17e-02	23
GO:0044819	GO:0044819	mitotic G1/S transition checkpoint	9/1061	23/8380	3.09	1.25e-03	2.17e-02	23
GO:1902806	GO:1902806	regulation of cell cycle G1/S phase transition	18/1061	67/8380	2.12	1.28e-03	2.21e-02	67
GO:0016233	GO:0016233	telomere capping	7/1061	15/8380	3.69	1.31e-03	2.24e-02	15
GO:0019941	GO:0019941	modification-dependent protein catabolic process	33/1061	153/8380	1.70	1.31e-03	2.24e-02	153
GO:0072698	GO:0072698	protein localization to microtubule cytoskeleton	8/1061	19/8380	3.33	1.34e-03	2.27e-02	19
GO:0006733	GO:0006733	oxidoreduction coenzyme metabolic process	21/1061	84/8380	1.97	1.45e-03	2.45e-02	84
GO:0043632	GO:0043632	modification-dependent macromolecule catabolic process	33/1061	154/8380	1.69	1.47e-03	2.48e-02	154
GO:0072395	GO:0072395	signal transduction involved in cell cycle checkpoint	10/1061	28/8380	2.82	1.54e-03	2.59e-02	28
GO:0010639	GO:0010639	negative regulation of organelle organization	35/1061	167/8380	1.66	1.61e-03	2.70e-02	167
GO:1901361	GO:1901361	organic cyclic compound catabolic process	50/1061	262/8380	1.51	1.70e-03	2.83e-02	262
GO:0031047	GO:0031047	gene silencing by RNA	16/1061	58/8380	2.18	1.74e-03	2.88e-02	58
GO:0018149	GO:0018149	peptide cross-linking	12/1061	38/8380	2.49	1.84e-03	3.02e-02	38
GO:0044774	GO:0044774	mitotic DNA integrity checkpoint	12/1061	38/8380	2.49	1.84e-03	3.02e-02	38
GO:0031297	GO:0031297	replication fork processing	6/1061	12/8380	3.95	1.90e-03	3.10e-02	12
GO:1900034	GO:1900034	regulation of cellular response to heat	6/1061	12/8380	3.95	1.90e-03	3.10e-02	12
GO:1902751	GO:1902751	positive regulation of cell cycle G2/M phase transition	8/1061	20/8380	3.16	1.99e-03	3.22e-02	20
GO:0051653	GO:0051653	spindle localization	7/1061	16/8380	3.46	2.07e-03	3.35e-02	16
GO:0006511	GO:0006511	ubiquitin-dependent protein catabolic process	32/1061	151/8380	1.67	2.08e-03	3.35e-02	151
GO:0034660	GO:0034660	ncRNA metabolic process	22/1061	92/8380	1.89	2.09e-03	3.35e-02	92
GO:0034470	GO:0034470	ncRNA processing	15/1061	54/8380	2.19	2.22e-03	3.55e-02	54
GO:0051053	GO:0051053	negative regulation of DNA metabolic process	14/1061	49/8380	2.26	2.31e-03	3.68e-02	49
GO:2001243	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	13/1061	44/8380	2.33	2.36e-03	3.74e-02	44
GO:0090559	GO:0090559	regulation of membrane permeability	9/1061	25/8380	2.84	2.48e-03	3.91e-02	25
GO:0019362	GO:0019362	pyridine nucleotide metabolic process	20/1061	82/8380	1.93	2.55e-03	3.99e-02	82
GO:0046496	GO:0046496	nicotinamide nucleotide metabolic process	20/1061	82/8380	1.93	2.55e-03	3.99e-02	82
GO:0010608	GO:0010608	posttranscriptional regulation of gene expression	32/1061	153/8380	1.65	2.59e-03	4.04e-02	153
GO:0051784	GO:0051784	negative regulation of nuclear division	10/1061	30/8380	2.63	2.79e-03	4.33e-02	30
GO:0050792	GO:0050792	regulation of viral process	19/1061	77/8380	1.95	2.80e-03	4.34e-02	77
GO:0038111	GO:0038111	interleukin-7-mediated signaling pathway	8/1061	21/8380	3.01	2.86e-03	4.40e-02	21
GO:0009435	GO:0009435	NAD biosynthetic process	11/1061	35/8380	2.48	2.94e-03	4.52e-02	35
GO:0009141	GO:0009141	nucleoside triphosphate metabolic process	25/1061	112/8380	1.76	2.97e-03	4.55e-02	112
GO:0046365	GO:0046365	monosaccharide catabolic process	12/1061	40/8380	2.37	2.98e-03	4.55e-02	40
GO:0006066	GO:0006066	alcohol metabolic process	41/1061	211/8380	1.53	3.05e-03	4.62e-02	211
GO:0043901	GO:0043901	negative regulation of multi-organism process	21/1061	89/8380	1.86	3.10e-03	4.67e-02	89
GO:0060969	GO:0060969	negative regulation of gene silencing	7/1061	17/8380	3.25	3.14e-03	4.67e-02	17
GO:0061077	GO:0061077	chaperone-mediated protein folding	7/1061	17/8380	3.25	3.14e-03	4.67e-02	17
GO:0061615	GO:0061615	glycolytic process through fructose-6-phosphate	7/1061	17/8380	3.25	3.14e-03	4.67e-02	17
GO:0061620	GO:0061620	glycolytic process through glucose-6-phosphate	7/1061	17/8380	3.25	3.14e-03	4.67e-02	17
GO:0010833	GO:0010833	telomere maintenance via telomere lengthening	6/1061	13/8380	3.65	3.16e-03	4.69e-02	13
GO:0043903	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	22/1061	95/8380	1.83	3.21e-03	4.74e-02	95
GO:0006839	GO:0006839	mitochondrial transport	17/1061	67/8380	2.00	3.36e-03	4.94e-02	67
GO:0006119	GO:0006119	oxidative phosphorylation	9/1061	26/8380	2.73	3.37e-03	4.95e-02	26

GATA3_LOF_up : 84 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001578	GO:0001578	microtubule bundle formation	31/1269	58/8380	3.53	1.13e-11	2.65e-08	58
GO:0035082	GO:0035082	axoneme assembly	26/1269	43/8380	3.99	1.19e-11	2.65e-08	43
GO:0044782	GO:0044782	cilium organization	56/1269	151/8380	2.45	2.06e-11	3.07e-08	151
GO:0060271	GO:0060271	cilium assembly	53/1269	140/8380	2.50	2.89e-11	3.22e-08	140
GO:0007017	GO:0007017	microtubule-based process	95/1269	335/8380	1.87	1.92e-10	1.71e-07	335
GO:0003341	GO:0003341	cilium movement	24/1269	42/8380	3.77	3.88e-10	2.88e-07	42
GO:0070286	GO:0070286	axonemal dynein complex assembly	16/1269	23/8380	4.59	5.98e-09	3.81e-06	23
GO:0000183	GO:0000183	chromatin silencing at rDNA	14/1269	19/8380	4.87	1.72e-08	9.57e-06	19
GO:0006334	GO:0006334	nucleosome assembly	30/1269	71/8380	2.79	3.20e-08	1.59e-05	71
GO:0034728	GO:0034728	nucleosome organization	32/1269	80/8380	2.64	5.42e-08	2.29e-05	80
GO:0006333	GO:0006333	chromatin assembly or disassembly	33/1269	84/8380	2.59	5.65e-08	2.29e-05	84
GO:0006335	GO:0006335	DNA replication-dependent nucleosome assembly	13/1269	18/8380	4.77	8.46e-08	2.90e-05	18
GO:0034723	GO:0034723	DNA replication-dependent nucleosome organization	13/1269	18/8380	4.77	8.46e-08	2.90e-05	18
GO:0031497	GO:0031497	chromatin assembly	31/1269	78/8380	2.62	1.04e-07	3.32e-05	78
GO:0034622	GO:0034622	cellular protein-containing complex assembly	102/1269	413/8380	1.63	1.31e-07	3.90e-05	413
GO:0017158	GO:0017158	regulation of calcium ion-dependent exocytosis	30/1269	75/8380	2.64	1.41e-07	3.93e-05	75
GO:0007018	GO:0007018	microtubule-based movement	42/1269	125/8380	2.22	1.79e-07	4.64e-05	125
GO:0017156	GO:0017156	calcium ion regulated exocytosis	37/1269	104/8380	2.35	1.87e-07	4.64e-05	104
GO:0045956	GO:0045956	positive regulation of calcium ion-dependent exocytosis	14/1269	22/8380	4.20	3.01e-07	7.06e-05	22
GO:0000226	GO:0000226	microtubule cytoskeleton organization	69/1269	253/8380	1.80	3.30e-07	7.35e-05	253
GO:0006342	GO:0006342	chromatin silencing	19/1269	38/8380	3.30	4.60e-07	9.77e-05	38
GO:0006323	GO:0006323	DNA packaging	34/1269	96/8380	2.34	6.60e-07	1.34e-04	96
GO:0016233	GO:0016233	telomere capping	11/1269	15/8380	4.84	6.99e-07	1.35e-04	15
GO:0120031	GO:0120031	plasma membrane bounded cell projection assembly	67/1269	251/8380	1.76	1.14e-06	2.11e-04	251
GO:0051291	GO:0051291	protein heterooligomerization	26/1269	66/8380	2.60	1.35e-06	2.41e-04	66
GO:0065004	GO:0065004	protein-DNA complex assembly	33/1269	96/8380	2.27	2.07e-06	3.56e-04	96
GO:0030031	GO:0030031	cell projection assembly	68/1269	262/8380	1.71	2.80e-06	4.52e-04	262
GO:0060968	GO:0060968	regulation of gene silencing	21/1269	49/8380	2.83	2.84e-06	4.52e-04	49
GO:0071824	GO:0071824	protein-DNA complex subunit organization	35/1269	107/8380	2.16	3.77e-06	5.79e-04	107
GO:0051290	GO:0051290	protein heterotetramerization	14/1269	26/8380	3.56	4.99e-06	7.31e-04	26
GO:0060964	GO:0060964	regulation of gene silencing by miRNA	17/1269	36/8380	3.12	5.08e-06	7.31e-04	36
GO:0045814	GO:0045814	negative regulation of gene expression, epigenetic	19/1269	44/8380	2.85	7.37e-06	1.03e-03	44
GO:0016079	GO:0016079	synaptic vesicle exocytosis	29/1269	84/8380	2.28	7.74e-06	1.05e-03	84
GO:0051650	GO:0051650	establishment of vesicle localization	40/1269	134/8380	1.97	1.00e-05	1.31e-03	134
GO:0060147	GO:0060147	regulation of posttranscriptional gene silencing	17/1269	38/8380	2.95	1.26e-05	1.56e-03	38
GO:0060966	GO:0060966	regulation of gene silencing by RNA	17/1269	38/8380	2.95	1.26e-05	1.56e-03	38
GO:0023061	GO:0023061	signal release	76/1269	316/8380	1.59	1.53e-05	1.83e-03	316
GO:0044458	GO:0044458	motile cilium assembly	9/1269	13/8380	4.57	1.64e-05	1.83e-03	13
GO:0051648	GO:0051648	vesicle localization	42/1269	146/8380	1.90	1.66e-05	1.83e-03	146
GO:0006325	GO:0006325	chromatin organization	67/1269	270/8380	1.64	1.67e-05	1.83e-03	270
GO:0030072	GO:0030072	peptide hormone secretion	47/1269	170/8380	1.83	1.69e-05	1.83e-03	170
GO:0001539	GO:0001539	cilium or flagellum-dependent cell motility	12/1269	22/8380	3.60	2.04e-05	2.11e-03	22
GO:0060285	GO:0060285	cilium-dependent cell motility	12/1269	22/8380	3.60	2.04e-05	2.11e-03	22
GO:0036159	GO:0036159	inner dynein arm assembly	8/1269	11/8380	4.80	2.91e-05	2.95e-03	11
GO:0035195	GO:0035195	gene silencing by miRNA	18/1269	45/8380	2.64	4.49e-05	4.45e-03	45
GO:0097479	GO:0097479	synaptic vesicle localization	32/1269	105/8380	2.01	4.82e-05	4.55e-03	105
GO:0048489	GO:0048489	synaptic vesicle transport	30/1269	96/8380	2.06	4.89e-05	4.55e-03	96
GO:0097480	GO:0097480	establishment of synaptic vesicle localization	30/1269	96/8380	2.06	4.89e-05	4.55e-03	96
GO:0030073	GO:0030073	insulin secretion	39/1269	138/8380	1.87	5.09e-05	4.63e-03	138
GO:0099504	GO:0099504	synaptic vesicle cycle	36/1269	124/8380	1.92	5.29e-05	4.71e-03	124
GO:0036158	GO:0036158	outer dynein arm assembly	8/1269	12/8380	4.40	7.57e-05	6.62e-03	12
GO:0090276	GO:0090276	regulation of peptide hormone secretion	40/1269	146/8380	1.81	8.76e-05	7.43e-03	146
GO:0032200	GO:0032200	telomere organization	18/1269	47/8380	2.53	8.84e-05	7.43e-03	47
GO:0017157	GO:0017157	regulation of exocytosis	37/1269	133/8380	1.84	1.13e-04	9.27e-03	133
GO:0046879	GO:0046879	hormone secretion	54/1269	218/8380	1.64	1.14e-04	9.27e-03	218
GO:0071103	GO:0071103	DNA conformation change	34/1269	120/8380	1.87	1.43e-04	1.14e-02	120
GO:0045652	GO:0045652	regulation of megakaryocyte differentiation	15/1269	37/8380	2.68	1.61e-04	1.23e-02	37
GO:0009914	GO:0009914	hormone transport	55/1269	226/8380	1.61	1.63e-04	1.23e-02	226
GO:0016441	GO:0016441	posttranscriptional gene silencing	18/1269	49/8380	2.43	1.65e-04	1.23e-02	49
GO:0035194	GO:0035194	posttranscriptional gene silencing by RNA	18/1269	49/8380	2.43	1.65e-04	1.23e-02	49
GO:0007269	GO:0007269	neurotransmitter secretion	33/1269	117/8380	1.86	1.96e-04	1.41e-02	117
GO:0099643	GO:0099643	signal release from synapse	33/1269	117/8380	1.86	1.96e-04	1.41e-02	117
GO:0050796	GO:0050796	regulation of insulin secretion	34/1269	122/8380	1.84	2.03e-04	1.44e-02	122
GO:0045921	GO:0045921	positive regulation of exocytosis	19/1269	54/8380	2.32	2.12e-04	1.45e-02	54
GO:2000300	GO:2000300	regulation of synaptic vesicle exocytosis	19/1269	54/8380	2.32	2.12e-04	1.45e-02	54
GO:0099003	GO:0099003	vesicle-mediated transport in synapse	33/1269	118/8380	1.85	2.33e-04	1.58e-02	118
GO:1903305	GO:1903305	regulation of regulated secretory pathway	30/1269	105/8380	1.89	2.95e-04	1.96e-02	105
GO:0140029	GO:0140029	exocytic process	17/1269	47/8380	2.39	3.10e-04	2.02e-02	47
GO:0099500	GO:0099500	vesicle fusion to plasma membrane	9/1269	17/8380	3.50	3.12e-04	2.02e-02	17
GO:1903307	GO:1903307	positive regulation of regulated secretory pathway	15/1269	39/8380	2.54	3.21e-04	2.05e-02	39
GO:0098693	GO:0098693	regulation of synaptic vesicle cycle	23/1269	74/8380	2.05	3.94e-04	2.48e-02	74
GO:0021700	GO:0021700	developmental maturation	46/1269	187/8380	1.62	4.23e-04	2.62e-02	187
GO:1902803	GO:1902803	regulation of synaptic vesicle transport	19/1269	57/8380	2.20	4.68e-04	2.85e-02	57
GO:0001505	GO:0001505	regulation of neurotransmitter levels	56/1269	241/8380	1.53	5.05e-04	3.00e-02	241
GO:0031047	GO:0031047	gene silencing by RNA	19/1269	58/8380	2.16	5.98e-04	3.51e-02	58
GO:0006839	GO:0006839	mitochondrial transport	21/1269	67/8380	2.07	6.14e-04	3.56e-02	67
GO:0003351	GO:0003351	epithelial cilium movement	8/1269	15/8380	3.52	6.42e-04	3.60e-02	15
GO:0016458	GO:0016458	gene silencing	24/1269	81/8380	1.96	6.50e-04	3.60e-02	81
GO:0030317	GO:0030317	flagellated sperm motility	18/1269	54/8380	2.20	6.55e-04	3.60e-02	54
GO:0097722	GO:0097722	sperm motility	18/1269	54/8380	2.20	6.55e-04	3.60e-02	54
GO:0006904	GO:0006904	vesicle docking involved in exocytosis	10/1269	22/8380	3.00	6.91e-04	3.69e-02	22
GO:1990542	GO:1990542	mitochondrial transmembrane transport	10/1269	22/8380	3.00	6.91e-04	3.69e-02	22
GO:0046883	GO:0046883	regulation of hormone secretion	46/1269	191/8380	1.59	6.94e-04	3.69e-02	191
GO:0051656	GO:0051656	establishment of organelle localization	52/1269	223/8380	1.54	7.25e-04	3.80e-02	223

GATA3_LOF_down : 89 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0001501	GO:0001501	skeletal system development	122/1746	351/8380	1.67	4.62e-10	2.05e-06	351
GO:0016055	GO:0016055	Wnt signaling pathway	96/1746	262/8380	1.76	1.60e-09	2.37e-06	262
GO:0198738	GO:0198738	cell-cell signaling by wnt	96/1746	262/8380	1.76	1.60e-09	2.37e-06	262
GO:0030111	GO:0030111	regulation of Wnt signaling pathway	70/1746	183/8380	1.84	3.75e-08	4.17e-05	183
GO:0002062	GO:0002062	chondrocyte differentiation	41/1746	89/8380	2.21	7.46e-08	6.64e-05	89
GO:0043588	GO:0043588	skin development	84/1746	242/8380	1.67	2.73e-07	2.02e-04	242
GO:0060828	GO:0060828	regulation of canonical Wnt signaling pathway	54/1746	137/8380	1.89	4.42e-07	2.81e-04	137
GO:0060070	GO:0060070	canonical Wnt signaling pathway	63/1746	170/8380	1.78	6.70e-07	3.72e-04	170
GO:0030178	GO:0030178	negative regulation of Wnt signaling pathway	44/1746	106/8380	1.99	9.73e-07	4.46e-04	106
GO:0051216	GO:0051216	cartilage development	58/1746	154/8380	1.81	1.00e-06	4.46e-04	154
GO:0007423	GO:0007423	sensory organ development	111/1746	354/8380	1.50	1.35e-06	5.46e-04	354
GO:0002009	GO:0002009	morphogenesis of an epithelium	101/1746	317/8380	1.53	1.83e-06	6.27e-04	317
GO:0061448	GO:0061448	connective tissue development	67/1746	190/8380	1.69	2.35e-06	7.45e-04	190
GO:0001503	GO:0001503	ossification	83/1746	252/8380	1.58	3.66e-06	1.02e-03	252
GO:0048568	GO:0048568	embryonic organ development	93/1746	293/8380	1.52	5.61e-06	1.41e-03	293
GO:0030198	GO:0030198	extracellular matrix organization	92/1746	290/8380	1.52	6.45e-06	1.51e-03	290
GO:0048562	GO:0048562	embryonic organ morphogenesis	72/1746	215/8380	1.61	8.36e-06	1.86e-03	215
GO:0070268	GO:0070268	cornification	38/1746	95/8380	1.92	1.48e-05	2.82e-03	95
GO:0090090	GO:0090090	negative regulation of canonical Wnt signaling pathway	35/1746	85/8380	1.98	1.52e-05	2.82e-03	85
GO:0008544	GO:0008544	epidermis development	86/1746	274/8380	1.51	2.03e-05	3.09e-03	274
GO:0030326	GO:0030326	embryonic limb morphogenesis	35/1746	86/8380	1.95	2.06e-05	3.09e-03	86
GO:0035113	GO:0035113	embryonic appendage morphogenesis	35/1746	86/8380	1.95	2.06e-05	3.09e-03	86
GO:0055123	GO:0055123	digestive system development	42/1746	110/8380	1.83	2.08e-05	3.09e-03	110
GO:0001655	GO:0001655	urogenital system development	79/1746	247/8380	1.54	2.09e-05	3.09e-03	247
GO:0048705	GO:0048705	skeletal system morphogenesis	59/1746	172/8380	1.65	2.42e-05	3.47e-03	172
GO:0048839	GO:0048839	inner ear development	50/1746	140/8380	1.71	2.99e-05	4.15e-03	140
GO:0048565	GO:0048565	digestive tract development	40/1746	105/8380	1.83	3.45e-05	4.38e-03	105
GO:0072001	GO:0072001	renal system development	71/1746	221/8380	1.54	4.60e-05	5.68e-03	221
GO:0043583	GO:0043583	ear development	54/1746	157/8380	1.65	4.86e-05	5.75e-03	157
GO:0035107	GO:0035107	appendage morphogenesis	39/1746	103/8380	1.82	5.04e-05	5.75e-03	103
GO:0035108	GO:0035108	limb morphogenesis	39/1746	103/8380	1.82	5.04e-05	5.75e-03	103
GO:0021915	GO:0021915	neural tube development	34/1746	86/8380	1.90	5.47e-05	6.08e-03	86
GO:0042475	GO:0042475	odontogenesis of dentin-containing tooth	28/1746	66/8380	2.04	5.62e-05	6.09e-03	66
GO:0010718	GO:0010718	positive regulation of epithelial to mesenchymal transition	18/1746	35/8380	2.47	5.83e-05	6.17e-03	35
GO:0035148	GO:0035148	tube formation	33/1746	83/8380	1.91	6.14e-05	6.20e-03	83
GO:0042476	GO:0042476	odontogenesis	37/1746	97/8380	1.83	6.49e-05	6.42e-03	97
GO:0060348	GO:0060348	bone development	49/1746	141/8380	1.67	7.97e-05	7.70e-03	141
GO:0001841	GO:0001841	neural tube formation	23/1746	51/8380	2.16	8.23e-05	7.79e-03	51
GO:0098773	GO:0098773	skin epidermis development	26/1746	61/8380	2.05	9.34e-05	8.65e-03	61
GO:0060485	GO:0060485	mesenchyme development	61/1746	187/8380	1.57	9.53e-05	8.65e-03	187
GO:0030216	GO:0030216	keratinocyte differentiation	54/1746	161/8380	1.61	1.05e-04	9.24e-03	161
GO:0001838	GO:0001838	embryonic epithelial tube formation	28/1746	68/8380	1.98	1.06e-04	9.24e-03	68
GO:0001822	GO:0001822	kidney development	66/1746	207/8380	1.53	1.09e-04	9.29e-03	207
GO:0014020	GO:0014020	primary neural tube formation	22/1746	49/8380	2.15	1.27e-04	1.07e-02	49
GO:0010463	GO:0010463	mesenchymal cell proliferation	18/1746	37/8380	2.33	1.48e-04	1.16e-02	37
GO:0001649	GO:0001649	osteoblast differentiation	46/1746	133/8380	1.66	1.48e-04	1.16e-02	133
GO:0001942	GO:0001942	hair follicle development	25/1746	60/8380	2.00	1.96e-04	1.50e-02	60
GO:0060562	GO:0060562	epithelial tube morphogenesis	65/1746	207/8380	1.51	2.00e-04	1.51e-02	207
GO:0042303	GO:0042303	molting cycle	29/1746	74/8380	1.88	2.26e-04	1.62e-02	74
GO:0042633	GO:0042633	hair cycle	29/1746	74/8380	1.88	2.26e-04	1.62e-02	74
GO:0072175	GO:0072175	epithelial tube formation	29/1746	74/8380	1.88	2.26e-04	1.62e-02	74
GO:0003007	GO:0003007	heart morphogenesis	57/1746	177/8380	1.55	2.34e-04	1.64e-02	177
GO:0060350	GO:0060350	endochondral bone morphogenesis	23/1746	54/8380	2.04	2.37e-04	1.64e-02	54
GO:0014033	GO:0014033	neural crest cell differentiation	26/1746	64/8380	1.95	2.40e-04	1.64e-02	64
GO:0048762	GO:0048762	mesenchymal cell differentiation	48/1746	143/8380	1.61	2.43e-04	1.64e-02	143
GO:0009913	GO:0009913	epidermal cell differentiation	61/1746	193/8380	1.52	2.55e-04	1.67e-02	193
GO:0048736	GO:0048736	appendage development	42/1746	121/8380	1.67	2.59e-04	1.67e-02	121
GO:0060173	GO:0060173	limb development	42/1746	121/8380	1.67	2.59e-04	1.67e-02	121
GO:0022404	GO:0022404	molting cycle process	25/1746	61/8380	1.97	2.67e-04	1.67e-02	61
GO:0022405	GO:0022405	hair cycle process	25/1746	61/8380	1.97	2.67e-04	1.67e-02	61
GO:0010715	GO:0010715	regulation of extracellular matrix disassembly	8/1746	11/8380	3.49	3.14e-04	1.94e-02	11
GO:0060021	GO:0060021	roof of mouth development	26/1746	65/8380	1.92	3.22e-04	1.96e-02	65
GO:0035329	GO:0035329	hippo signaling	10/1746	16/8380	3.00	3.48e-04	2.06e-02	16
GO:0060973	GO:0060973	cell migration involved in heart development	10/1746	16/8380	3.00	3.48e-04	2.06e-02	16
GO:0003205	GO:0003205	cardiac chamber development	41/1746	119/8380	1.65	3.64e-04	2.13e-02	119
GO:0061035	GO:0061035	regulation of cartilage development	21/1746	49/8380	2.06	3.96e-04	2.25e-02	49
GO:0048863	GO:0048863	stem cell differentiation	46/1746	139/8380	1.59	4.64e-04	2.49e-02	139
GO:0016331	GO:0016331	morphogenesis of embryonic epithelium	33/1746	91/8380	1.74	4.71e-04	2.49e-02	91
GO:0031424	GO:0031424	keratinization	39/1746	113/8380	1.66	4.82e-04	2.52e-02	113
GO:0060349	GO:0060349	bone morphogenesis	31/1746	84/8380	1.77	4.88e-04	2.52e-02	84
GO:0032330	GO:0032330	regulation of chondrocyte differentiation	17/1746	37/8380	2.21	5.28e-04	2.70e-02	37
GO:0003279	GO:0003279	cardiac septum development	28/1746	74/8380	1.82	5.67e-04	2.83e-02	74
GO:0001843	GO:0001843	neural tube closure	19/1746	44/8380	2.07	6.61e-04	3.19e-02	44
GO:1904888	GO:1904888	cranial skeletal system development	19/1746	44/8380	2.07	6.61e-04	3.19e-02	44
GO:0010717	GO:0010717	regulation of epithelial to mesenchymal transition	22/1746	54/8380	1.96	6.77e-04	3.21e-02	54
GO:0032331	GO:0032331	negative regulation of chondrocyte differentiation	10/1746	17/8380	2.82	6.87e-04	3.21e-02	17
GO:0072234	GO:0072234	metanephric nephron tubule development	10/1746	17/8380	2.82	6.87e-04	3.21e-02	17
GO:0021782	GO:0021782	glial cell development	26/1746	68/8380	1.84	7.32e-04	3.30e-02	68
GO:0035051	GO:0035051	cardiocyte differentiation	34/1746	97/8380	1.68	7.91e-04	3.52e-02	97
GO:0060351	GO:0060351	cartilage development involved in endochondral bone morphogenesis	16/1746	35/8380	2.19	8.21e-04	3.58e-02	35
GO:1905207	GO:1905207	regulation of cardiocyte differentiation	16/1746	35/8380	2.19	8.21e-04	3.58e-02	35
GO:0043616	GO:0043616	keratinocyte proliferation	15/1746	32/8380	2.25	8.62e-04	3.67e-02	32
GO:0010837	GO:0010837	regulation of keratinocyte proliferation	12/1746	23/8380	2.50	8.66e-04	3.67e-02	23
GO:2000826	GO:2000826	regulation of heart morphogenesis	14/1746	29/8380	2.32	8.87e-04	3.72e-02	29
GO:0071559	GO:0071559	response to transforming growth factor beta	45/1746	139/8380	1.55	9.01e-04	3.74e-02	139
GO:0060606	GO:0060606	tube closure	19/1746	45/8380	2.03	9.23e-04	3.80e-02	45
GO:0048704	GO:0048704	embryonic skeletal system morphogenesis	27/1746	73/8380	1.78	1.06e-03	4.32e-02	73
GO:0006677	GO:0006677	glycosylceramide metabolic process	7/1746	10/8380	3.36	1.11e-03	4.46e-02	10
GO:0072170	GO:0072170	metanephric tubule development	10/1746	18/8380	2.67	1.26e-03	5.00e-02	18

PIK3CA_mis_up : 11 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0044782	GO:0044782	cilium organization	84/2707	151/8380	1.72	2.14e-09	1.04e-05	151
GO:0060271	GO:0060271	cilium assembly	77/2707	140/8380	1.70	1.96e-08	4.78e-05	140
GO:0003341	GO:0003341	cilium movement	31/2707	42/8380	2.28	3.94e-08	6.39e-05	42
GO:0035082	GO:0035082	axoneme assembly	31/2707	43/8380	2.23	9.74e-08	1.19e-04	43
GO:0070286	GO:0070286	axonemal dynein complex assembly	19/2707	23/8380	2.56	9.38e-07	9.14e-04	23
GO:0007156	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	74/2707	149/8380	1.54	6.84e-06	5.56e-03	149
GO:0007031	GO:0007031	peroxisome organization	22/2707	31/8380	2.20	1.13e-05	7.06e-03	31
GO:0060216	GO:0060216	definitive hemopoiesis	12/2707	13/8380	2.86	1.16e-05	7.06e-03	13
GO:0001578	GO:0001578	microtubule bundle formation	34/2707	58/8380	1.81	3.12e-05	1.25e-02	58
GO:0036158	GO:0036158	outer dynein arm assembly	11/2707	12/8380	2.84	3.33e-05	1.25e-02	12
GO:0044458	GO:0044458	motile cilium assembly	11/2707	13/8380	2.62	1.53e-04	4.38e-02	13

PIK3CA_mis_down : 148 significant GO terms
	ID	Description	GeneRatio	BgRatio	FoldChange	pvalue	qvalue	GS_size
GO:0000278	GO:0000278	mitotic cell cycle	218/2912	370/8380	1.70	2.62e-22	1.13e-18	370
GO:1903047	GO:1903047	mitotic cell cycle process	189/2912	309/8380	1.76	4.84e-22	1.13e-18	309
GO:0007059	GO:0007059	chromosome segregation	91/2912	126/8380	2.08	6.41e-18	9.96e-15	126
GO:0051276	GO:0051276	chromosome organization	218/2912	406/8380	1.55	8.93e-16	1.04e-12	406
GO:0098813	GO:0098813	nuclear chromosome segregation	80/2912	112/8380	2.06	1.86e-15	1.74e-12	112
GO:0006260	GO:0006260	DNA replication	71/2912	96/8380	2.13	3.74e-15	2.91e-12	96
GO:0051301	GO:0051301	cell division	148/2912	255/8380	1.67	1.10e-14	7.30e-12	255
GO:0044772	GO:0044772	mitotic cell cycle phase transition	118/2912	191/8380	1.78	1.26e-14	7.35e-12	191
GO:0000819	GO:0000819	sister chromatid segregation	59/2912	76/8380	2.23	1.97e-14	1.02e-11	76
GO:0000070	GO:0000070	mitotic sister chromatid segregation	49/2912	60/8380	2.35	9.24e-14	4.31e-11	60
GO:0044770	GO:0044770	cell cycle phase transition	122/2912	206/8380	1.70	3.55e-13	1.50e-10	206
GO:0000280	GO:0000280	nuclear division	118/2912	198/8380	1.72	4.75e-13	1.85e-10	198
GO:0006261	GO:0006261	DNA-dependent DNA replication	45/2912	55/8380	2.35	8.54e-13	3.06e-10	55
GO:0140014	GO:0140014	mitotic nuclear division	80/2912	122/8380	1.89	2.86e-12	8.94e-10	122
GO:0006259	GO:0006259	DNA metabolic process	175/2912	330/8380	1.53	3.03e-12	8.94e-10	330
GO:0048285	GO:0048285	organelle fission	124/2912	215/8380	1.66	3.07e-12	8.94e-10	215
GO:0071103	GO:0071103	DNA conformation change	76/2912	120/8380	1.82	1.25e-10	3.44e-08	120
GO:0007346	GO:0007346	regulation of mitotic cell cycle	128/2912	237/8380	1.55	5.87e-10	1.44e-07	237
GO:0051983	GO:0051983	regulation of chromosome segregation	33/2912	40/8380	2.37	6.80e-10	1.59e-07	40
GO:0006270	GO:0006270	DNA replication initiation	16/2912	16/8380	2.88	4.40e-08	9.32e-06	16
GO:0000075	GO:0000075	cell cycle checkpoint	48/2912	73/8380	1.89	5.91e-08	1.18e-05	73
GO:0006281	GO:0006281	DNA repair	84/2912	150/8380	1.61	6.47e-08	1.18e-05	150
GO:0000082	GO:0000082	G1/S transition of mitotic cell cycle	61/2912	100/8380	1.76	6.53e-08	1.18e-05	100
GO:0032508	GO:0032508	DNA duplex unwinding	20/2912	22/8380	2.62	6.56e-08	1.18e-05	22
GO:0032392	GO:0032392	DNA geometric change	23/2912	27/8380	2.45	9.19e-08	1.54e-05	27
GO:1901990	GO:1901990	regulation of mitotic cell cycle phase transition	75/2912	131/8380	1.65	9.54e-08	1.54e-05	131
GO:1903046	GO:1903046	meiotic cell cycle process	63/2912	105/8380	1.73	9.61e-08	1.54e-05	105
GO:0051321	GO:0051321	meiotic cell cycle	74/2912	130/8380	1.64	1.60e-07	2.49e-05	130
GO:0044843	GO:0044843	cell cycle G1/S phase transition	64/2912	109/8380	1.69	2.35e-07	3.54e-05	109
GO:0140013	GO:0140013	meiotic nuclear division	59/2912	99/8380	1.72	3.40e-07	4.85e-05	99
GO:0006302	GO:0006302	double-strand break repair	50/2912	80/8380	1.80	3.43e-07	4.85e-05	80
GO:0007051	GO:0007051	spindle organization	41/2912	62/8380	1.90	4.35e-07	5.90e-05	62
GO:0051310	GO:0051310	metaphase plate congression	18/2912	20/8380	2.59	4.53e-07	5.90e-05	20
GO:1901987	GO:1901987	regulation of cell cycle phase transition	80/2912	146/8380	1.58	4.56e-07	5.90e-05	146
GO:0051304	GO:0051304	chromosome separation	29/2912	39/8380	2.14	4.93e-07	6.21e-05	39
GO:0033045	GO:0033045	regulation of sister chromatid segregation	25/2912	32/8380	2.25	6.26e-07	7.68e-05	32
GO:0000086	GO:0000086	G2/M transition of mitotic cell cycle	47/2912	75/8380	1.80	6.88e-07	8.23e-05	75
GO:0006396	GO:0006396	RNA processing	92/2912	175/8380	1.51	7.87e-07	8.88e-05	175
GO:0006310	GO:0006310	DNA recombination	59/2912	101/8380	1.68	8.79e-07	9.54e-05	101
GO:0044839	GO:0044839	cell cycle G2/M phase transition	50/2912	82/8380	1.75	1.02e-06	1.05e-04	82
GO:0070268	GO:0070268	cornification	56/2912	95/8380	1.70	1.11e-06	1.12e-04	95
GO:0090068	GO:0090068	positive regulation of cell cycle process	73/2912	133/8380	1.58	1.32e-06	1.31e-04	133
GO:0010389	GO:0010389	regulation of G2/M transition of mitotic cell cycle	35/2912	52/8380	1.94	1.63e-06	1.55e-04	52
GO:1902850	GO:1902850	microtubule cytoskeleton organization involved in mitosis	35/2912	52/8380	1.94	1.63e-06	1.55e-04	52
GO:0006323	GO:0006323	DNA packaging	56/2912	96/8380	1.68	1.77e-06	1.65e-04	96
GO:0010965	GO:0010965	regulation of mitotic sister chromatid separation	21/2912	26/8380	2.32	1.95e-06	1.65e-04	26
GO:0033047	GO:0033047	regulation of mitotic sister chromatid segregation	21/2912	26/8380	2.32	1.95e-06	1.65e-04	26
GO:0050000	GO:0050000	chromosome localization	21/2912	26/8380	2.32	1.95e-06	1.65e-04	26
GO:0051303	GO:0051303	establishment of chromosome localization	21/2912	26/8380	2.32	1.95e-06	1.65e-04	26
GO:0051306	GO:0051306	mitotic sister chromatid separation	21/2912	26/8380	2.32	1.95e-06	1.65e-04	26
GO:0007088	GO:0007088	regulation of mitotic nuclear division	53/2912	90/8380	1.69	2.23e-06	1.86e-04	90
GO:0000724	GO:0000724	double-strand break repair via homologous recombination	30/2912	43/8380	2.01	2.90e-06	2.33e-04	43
GO:0000725	GO:0000725	recombinational repair	30/2912	43/8380	2.01	2.90e-06	2.33e-04	43
GO:1902749	GO:1902749	regulation of cell cycle G2/M phase transition	38/2912	59/8380	1.85	3.05e-06	2.41e-04	59
GO:0007080	GO:0007080	mitotic metaphase plate congression	14/2912	15/8380	2.69	3.72e-06	2.89e-04	15
GO:0007091	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	20/2912	25/8380	2.30	4.57e-06	3.49e-04	25
GO:1905818	GO:1905818	regulation of chromosome separation	21/2912	27/8380	2.24	5.88e-06	4.42e-04	27
GO:0034470	GO:0034470	ncRNA processing	35/2912	54/8380	1.87	6.07e-06	4.43e-04	54
GO:0007052	GO:0007052	mitotic spindle organization	30/2912	44/8380	1.96	6.09e-06	4.43e-04	44
GO:0034502	GO:0034502	protein localization to chromosome	18/2912	22/8380	2.35	7.90e-06	5.67e-04	22
GO:0031424	GO:0031424	keratinization	62/2912	113/8380	1.58	8.31e-06	5.82e-04	113
GO:0061982	GO:0061982	meiosis I cell cycle process	41/2912	67/8380	1.76	8.36e-06	5.82e-04	67
GO:0051383	GO:0051383	kinetochore organization	11/2912	11/8380	2.88	8.81e-06	6.04e-04	11
GO:0007093	GO:0007093	mitotic cell cycle checkpoint	38/2912	61/8380	1.79	9.82e-06	6.63e-04	61
GO:0031145	GO:0031145	anaphase-promoting complex-dependent catabolic process	13/2912	14/8380	2.67	1.01e-05	6.69e-04	14
GO:0030071	GO:0030071	regulation of mitotic metaphase/anaphase transition	19/2912	24/8380	2.28	1.06e-05	6.98e-04	24
GO:0071824	GO:0071824	protein-DNA complex subunit organization	59/2912	107/8380	1.59	1.11e-05	7.21e-04	107
GO:0045132	GO:0045132	meiotic chromosome segregation	33/2912	51/8380	1.86	1.18e-05	7.48e-04	51
GO:0065004	GO:0065004	protein-DNA complex assembly	54/2912	96/8380	1.62	1.20e-05	7.48e-04	96
GO:0061844	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	32/2912	49/8380	1.88	1.20e-05	7.48e-04	49
GO:2001251	GO:2001251	negative regulation of chromosome organization	30/2912	45/8380	1.92	1.22e-05	7.49e-04	45
GO:0033046	GO:0033046	negative regulation of sister chromatid segregation	16/2912	19/8380	2.42	1.31e-05	7.73e-04	19
GO:0044786	GO:0044786	cell cycle DNA replication	16/2912	19/8380	2.42	1.31e-05	7.73e-04	19
GO:0051985	GO:0051985	negative regulation of chromosome segregation	16/2912	19/8380	2.42	1.31e-05	7.73e-04	19
GO:0044784	GO:0044784	metaphase/anaphase transition of cell cycle	20/2912	26/8380	2.21	1.33e-05	7.76e-04	26
GO:0051783	GO:0051783	regulation of nuclear division	56/2912	101/8380	1.60	1.49e-05	8.56e-04	101
GO:0007127	GO:0007127	meiosis I	39/2912	64/8380	1.75	1.59e-05	9.06e-04	64
GO:0007062	GO:0007062	sister chromatid cohesion	18/2912	23/8380	2.25	2.45e-05	1.38e-03	23
GO:0034508	GO:0034508	centromere complex assembly	19/2912	25/8380	2.19	2.98e-05	1.63e-03	25
GO:1902099	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	19/2912	25/8380	2.19	2.98e-05	1.63e-03	25
GO:0033048	GO:0033048	negative regulation of mitotic sister chromatid segregation	15/2912	18/8380	2.40	3.20e-05	1.68e-03	18
GO:1905819	GO:1905819	negative regulation of chromosome separation	15/2912	18/8380	2.40	3.20e-05	1.68e-03	18
GO:2000816	GO:2000816	negative regulation of mitotic sister chromatid separation	15/2912	18/8380	2.40	3.20e-05	1.68e-03	18
GO:0010948	GO:0010948	negative regulation of cell cycle process	59/2912	110/8380	1.54	3.39e-05	1.76e-03	110
GO:0034660	GO:0034660	ncRNA metabolic process	51/2912	92/8380	1.60	3.56e-05	1.83e-03	92
GO:0031055	GO:0031055	chromatin remodeling at centromere	17/2912	22/8380	2.22	5.58e-05	2.80e-03	22
GO:0045930	GO:0045930	negative regulation of mitotic cell cycle	59/2912	112/8380	1.52	6.76e-05	3.35e-03	112
GO:0031497	GO:0031497	chromatin assembly	44/2912	78/8380	1.62	6.90e-05	3.35e-03	78
GO:0031570	GO:0031570	DNA integrity checkpoint	31/2912	50/8380	1.78	7.36e-05	3.54e-03	50
GO:0008608	GO:0008608	attachment of spindle microtubules to kinetochore	14/2912	17/8380	2.37	7.75e-05	3.61e-03	17
GO:0045841	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	14/2912	17/8380	2.37	7.75e-05	3.61e-03	17
GO:1902100	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	14/2912	17/8380	2.37	7.75e-05	3.61e-03	17
GO:0051784	GO:0051784	negative regulation of nuclear division	21/2912	30/8380	2.01	8.64e-05	3.99e-03	30
GO:1901992	GO:1901992	positive regulation of mitotic cell cycle phase transition	26/2912	40/8380	1.87	8.97e-05	4.10e-03	40
GO:0007098	GO:0007098	centrosome cycle	25/2912	38/8380	1.89	9.12e-05	4.13e-03	38
GO:0033044	GO:0033044	regulation of chromosome organization	55/2912	104/8380	1.52	1.03e-04	4.61e-03	104
GO:1901988	GO:1901988	negative regulation of cell cycle phase transition	43/2912	77/8380	1.61	1.14e-04	5.07e-03	77
GO:0006336	GO:0006336	DNA replication-independent nucleosome assembly	16/2912	21/8380	2.19	1.26e-04	5.45e-03	21
GO:0034724	GO:0034724	DNA replication-independent nucleosome organization	16/2912	21/8380	2.19	1.26e-04	5.45e-03	21
GO:0006333	GO:0006333	chromatin assembly or disassembly	46/2912	84/8380	1.58	1.26e-04	5.45e-03	84
GO:0000083	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	12/2912	14/8380	2.47	1.29e-04	5.51e-03	14
GO:0032200	GO:0032200	telomere organization	29/2912	47/8380	1.78	1.42e-04	6.01e-03	47
GO:0006334	GO:0006334	nucleosome assembly	40/2912	71/8380	1.62	1.51e-04	6.28e-03	71
GO:0000910	GO:0000910	cytokinesis	35/2912	60/8380	1.68	1.52e-04	6.28e-03	60
GO:0034728	GO:0034728	nucleosome organization	44/2912	80/8380	1.58	1.54e-04	6.29e-03	80
GO:0045839	GO:0045839	negative regulation of mitotic nuclear division	19/2912	27/8380	2.03	1.70e-04	6.89e-03	27
GO:0006275	GO:0006275	regulation of DNA replication	24/2912	37/8380	1.87	1.76e-04	6.98e-03	37
GO:0070192	GO:0070192	chromosome organization involved in meiotic cell cycle	24/2912	37/8380	1.87	1.76e-04	6.98e-03	37
GO:0000281	GO:0000281	mitotic cytokinesis	20/2912	29/8380	1.98	1.77e-04	6.98e-03	29
GO:0051225	GO:0051225	spindle assembly	23/2912	35/8380	1.89	1.79e-04	7.02e-03	35
GO:0033260	GO:0033260	nuclear DNA replication	13/2912	16/8380	2.34	1.86e-04	7.21e-03	16
GO:0071459	GO:0071459	protein localization to chromosome, centromeric region	10/2912	11/8380	2.62	1.91e-04	7.32e-03	11
GO:0045931	GO:0045931	positive regulation of mitotic cell cycle	41/2912	74/8380	1.59	2.06e-04	7.76e-03	74
GO:1901989	GO:1901989	positive regulation of cell cycle phase transition	29/2912	48/8380	1.74	2.40e-04	8.95e-03	48
GO:1901991	GO:1901991	negative regulation of mitotic cell cycle phase transition	39/2912	70/8380	1.60	2.51e-04	9.27e-03	70
GO:0034080	GO:0034080	CENP-A containing nucleosome assembly	15/2912	20/8380	2.16	2.79e-04	1.01e-02	20
GO:0061641	GO:0061641	CENP-A containing chromatin organization	15/2912	20/8380	2.16	2.79e-04	1.01e-02	20
GO:0022613	GO:0022613	ribonucleoprotein complex biogenesis	33/2912	57/8380	1.67	2.84e-04	1.02e-02	57
GO:0061640	GO:0061640	cytoskeleton-dependent cytokinesis	23/2912	36/8380	1.84	3.34e-04	1.17e-02	36
GO:0006882	GO:0006882	cellular zinc ion homeostasis	17/2912	24/8380	2.04	3.35e-04	1.17e-02	24
GO:0043486	GO:0043486	histone exchange	17/2912	24/8380	2.04	3.35e-04	1.17e-02	24
GO:0007094	GO:0007094	mitotic spindle assembly checkpoint	12/2912	15/8380	2.30	4.39e-04	1.47e-02	15
GO:0031577	GO:0031577	spindle checkpoint	12/2912	15/8380	2.30	4.39e-04	1.47e-02	15
GO:0071173	GO:0071173	spindle assembly checkpoint	12/2912	15/8380	2.30	4.39e-04	1.47e-02	15
GO:0071174	GO:0071174	mitotic spindle checkpoint	12/2912	15/8380	2.30	4.39e-04	1.47e-02	15
GO:0051054	GO:0051054	positive regulation of DNA metabolic process	44/2912	83/8380	1.53	4.59e-04	1.53e-02	83
GO:0010273	GO:0010273	detoxification of copper ion	9/2912	10/8380	2.59	5.04e-04	1.66e-02	10
GO:1990169	GO:1990169	stress response to copper ion	9/2912	10/8380	2.59	5.04e-04	1.66e-02	10
GO:0010569	GO:0010569	regulation of double-strand break repair via homologous recombination	13/2912	17/8380	2.20	5.37e-04	1.75e-02	17
GO:0000723	GO:0000723	telomere maintenance	24/2912	39/8380	1.77	5.60e-04	1.81e-02	39
GO:0046605	GO:0046605	regulation of centrosome cycle	14/2912	19/8380	2.12	6.11e-04	1.95e-02	19
GO:0051298	GO:0051298	centrosome duplication	14/2912	19/8380	2.12	6.11e-04	1.95e-02	19
GO:1902750	GO:1902750	negative regulation of cell cycle G2/M phase transition	15/2912	21/8380	2.06	6.63e-04	2.10e-02	21
GO:0030866	GO:0030866	cortical actin cytoskeleton organization	16/2912	23/8380	2.00	6.94e-04	2.16e-02	23
GO:0030865	GO:0030865	cortical cytoskeleton organization	17/2912	25/8380	1.96	7.09e-04	2.16e-02	25
GO:0055069	GO:0055069	zinc ion homeostasis	17/2912	25/8380	1.96	7.09e-04	2.16e-02	25
GO:0031123	GO:0031123	RNA 3’-end processing	18/2912	27/8380	1.92	7.09e-04	2.16e-02	27
GO:2000779	GO:2000779	regulation of double-strand break repair	18/2912	27/8380	1.92	7.09e-04	2.16e-02	27
GO:0006338	GO:0006338	chromatin remodeling	32/2912	57/8380	1.62	7.37e-04	2.23e-02	57
GO:0071294	GO:0071294	cellular response to zinc ion	11/2912	14/8380	2.26	1.02e-03	3.02e-02	14
GO:0051653	GO:0051653	spindle localization	12/2912	16/8380	2.16	1.20e-03	3.49e-02	16
GO:0090329	GO:0090329	regulation of DNA-dependent DNA replication	12/2912	16/8380	2.16	1.20e-03	3.49e-02	16
GO:0035336	GO:0035336	long-chain fatty-acyl-CoA metabolic process	14/2912	20/8380	2.01	1.39e-03	3.89e-02	20
GO:0032481	GO:0032481	positive regulation of type I interferon production	17/2912	26/8380	1.88	1.39e-03	3.89e-02	26
GO:0043044	GO:0043044	ATP-dependent chromatin remodeling	17/2912	26/8380	1.88	1.39e-03	3.89e-02	26
GO:0031023	GO:0031023	microtubule organizing center organization	25/2912	43/8380	1.67	1.40e-03	3.92e-02	43
GO:0000018	GO:0000018	regulation of DNA recombination	24/2912	41/8380	1.68	1.53e-03	4.25e-02	41
GO:0042254	GO:0042254	ribosome biogenesis	22/2912	37/8380	1.71	1.80e-03	4.92e-02	37

Summary:
Mutation_status	TP53_LOF_up	TP53_LOF_down	TP53_mis_up	TP53_mis_down	CDH1_LOF_up
Signif_GO_terms	122	8	98	12	409
Mutation_status	CDH1_LOF_down	GATA3_LOF_up	GATA3_LOF_down	PIK3CA_mis_up	PIK3CA_mis_down
Signif_GO_terms	270	84	89	11	148

Guided Factor Analysis on TCGA BRCA Gene Expression Data

– Normalization: TMM, Guides: LOF and Missense Mutations Separated

Yifan Zhou (zhouyf@uchicago.edu)

2021-02-18