Permutation test — cis-gene analysis (t-test + ash)

Differential expression test on permutated sctransformed data

We still use the gene \(\times\) cell matrix holding sctransformed Pearson residuals. We filter out genes expressed in < 10% of all cells, and cells with no gRNA detected. For cis analysis, we focus only on the genes within \(\pm\) 200 kb/ 500 kb/ 1 MB of the SNP loci of interest.

In the original gRNA-based DE analysis, for each gRNA target (63 in total), we partitioned the cells into 2 groups: cells that contain the target gRNA , and cells that don’t contain the target gRNA.

In the permutation tests here, for each gRNA target, we divide the cells into 2 groups randomly, while keeping the number of cells in each group the same as before. Then, we conduct categorical regression on the Pearson residuals (based on the permuted conditions) to obtain the summary statistics. As before, all 63 partitions were tested, and test statistics are combined together for subsequent ash shrinkage.

# categoric regression function
source('~/Downloads/ASoC/singlecell/github/code/categoric_regression.R')
# permutation function: test for each gRNA target (1 vs others, conditions permuted)
permute_categ <- function(seed){
  set.seed(seed)
  perm.summary <- list()
  for (glocus in row.names(exp.per.gRNA)[-c(72:76)]){
    print(paste('gRNA target:',glocus))
    tg.cells <- colnames(exp.per.gRNA)[exp.per.gRNA[glocus,]>0]
    tg.indx <- sample(length(nonzero.cells),length(tg.cells))
    tg.cells <- nonzero.cells[tg.indx]
    neg.cells <- nonzero.cells[-tg.indx]
    perm.summary[[glocus]] <- categoric(subset.sctransform_data,tg.cells,neg.cells)
  }
  return(perm.summary)
}

Permutation 1

# summary_per_gene <- permute_categ(1952) # five random seeds: 1952 8076  966  275 7816
# saveRDS(summary_per_gene,file = paste0(wkdir,'data/cis.categ.perm.summary01.rds'))
summary_per_gene <- readRDS(paste0(wkdir,'data/cis.categ.perm.summary01.rds'))

ash on 200 kb cis genes

ash_on_scttest(summary_per_gene,full_genes.200kb.expanded,'gRNA')

255 data points:

cisGene	SNP	percentage	locus	gRNA	ttest.beta	ttest.se	ttest.pval	zscore	ash.beta	lfsr
APOPT1	rs7148456	0.855	BAG5	BAG5_1_gene	-0.021439	0.0944	0.82033	-0.22713	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_1_gene	-0.104670	0.0962	0.27643	-1.08855	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_1_gene	-0.054603	0.2143	0.79886	-0.25484	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_1_gene	-0.012855	0.1134	0.90977	-0.11333	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_1_gene	-0.070932	0.0935	0.44791	-0.75898	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_1_gene	0.028782	0.1029	0.77970	0.27973	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_1_gene	-0.037868	0.1055	0.71979	-0.35877	0.00e+00	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_1_gene	0.065409	0.0940	0.48678	0.69550	0.00e+00	1
APOPT1	rs7148456	0.855	BAG5	BAG5_2_gene	0.257083	0.0948	0.00670	2.71291	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_2_gene	-0.081595	0.0966	0.39854	-0.84433	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_2_gene	-0.092190	0.2153	0.66856	-0.42815	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_2_gene	0.107367	0.1140	0.34626	0.94199	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_2_gene	-0.091085	0.0939	0.33217	-0.96988	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_2_gene	0.047616	0.1034	0.64519	0.46050	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_2_gene	-0.027456	0.1061	0.79577	-0.25884	3.47e-18	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_2_gene	-0.167572	0.0945	0.07620	-1.77368	0.00e+00	1
APOPT1	rs7148456	0.855	BAG5	BAG5_3_gene	0.033054	0.1177	0.77892	0.28075	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_3_gene	0.083466	0.1200	0.48658	0.69582	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_3_gene	0.153230	0.2673	0.56644	0.57335	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_3_gene	0.271993	0.1414	0.05452	1.92332	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_3_gene	-0.027668	0.1166	0.81241	-0.23733	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_3_gene	-0.303720	0.1283	0.01793	-2.36817	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_3_gene	0.021582	0.1317	0.86980	0.16393	0.00e+00	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_3_gene	0.019631	0.1173	0.86711	0.16734	0.00e+00	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_1_gene	-0.442592	0.1350	0.00105	-3.27855	-5.55e-17	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_2_gene	-0.019737	0.0830	0.81208	-0.23775	0.00e+00	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_3_gene	-0.143051	0.1338	0.28519	-1.06890	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_1_gene	0.213782	0.2262	0.34475	0.94494	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_1_gene	-0.078635	0.2287	0.73104	-0.34377	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_1_gene	-0.010054	0.2147	0.96266	-0.04682	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_1_gene	0.333663	0.2064	0.10605	1.61658	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_2_gene	0.118609	0.1344	0.37772	0.88221	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_2_gene	-0.152981	0.1359	0.26041	-1.12560	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_2_gene	-0.074099	0.1276	0.56145	-0.58074	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_2_gene	0.147044	0.1227	0.23073	1.19867	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_3_gene	-0.214795	0.1661	0.19613	-1.29289	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_3_gene	0.009821	0.1680	0.95338	0.05846	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_3_gene	0.282164	0.1576	0.07353	1.79005	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_3_gene	-0.147882	0.1516	0.32944	-0.97537	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_1_gene	-0.068274	0.1000	0.49486	-0.68267	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_1_gene	0.133326	0.0960	0.16487	1.38916	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_2_gene	-0.036104	0.1042	0.72912	-0.34633	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_2_gene	0.130798	0.1000	0.19115	1.30742	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_3_gene	0.052448	0.0820	0.52222	0.63999	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_3_gene	0.051396	0.0787	0.51355	0.65339	6.94e-18	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_1_gene	0.012590	0.1101	0.90897	0.11434	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_1_gene	-0.042871	0.1062	0.68651	-0.40363	0.00e+00	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_1_gene	0.000295	0.2193	0.99893	0.00135	0.00e+00	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_1_gene	-0.052172	0.1266	0.68019	-0.41224	0.00e+00	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_1_gene	-0.016316	0.1000	0.87035	-0.16322	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_1_gene	-0.187460	0.1119	0.09399	-1.67515	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_1_gene	0.022581	0.1835	0.90209	0.12303	0.00e+00	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_1_gene	-0.079525	0.1057	0.45184	-0.75244	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_1_gene	-0.034502	0.1065	0.74587	-0.32411	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_1_gene	0.063456	0.1030	0.53779	0.61621	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_1_gene	0.061396	0.0970	0.52672	0.63309	-6.94e-18	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_1_gene	0.055258	0.1150	0.63090	0.48050	0.00e+00	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_1_gene	0.089667	0.1591	0.57304	0.56364	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_1_gene	0.110788	0.1036	0.28484	1.06965	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_1_gene	0.007900	0.1049	0.93996	0.07533	0.00e+00	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_1_gene	-0.108128	0.1126	0.33702	-0.96019	0.00e+00	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_2_gene	0.108078	0.1309	0.40911	0.82556	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_2_gene	-0.086724	0.1263	0.49232	-0.68669	0.00e+00	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_2_gene	-0.106476	0.2607	0.68303	-0.40836	-1.39e-17	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_2_gene	0.044530	0.1505	0.76733	0.29590	0.00e+00	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_2_gene	-0.063099	0.1189	0.59556	-0.53085	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_2_gene	0.288110	0.1330	0.03040	2.16568	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_2_gene	-0.234664	0.2182	0.28229	-1.07534	-2.78e-17	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_2_gene	0.185851	0.1256	0.13919	1.47913	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_2_gene	-0.095649	0.1266	0.44989	-0.75568	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_2_gene	-0.132721	0.1224	0.27845	-1.08398	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_2_gene	-0.005190	0.1153	0.96411	-0.04500	0.00e+00	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_2_gene	0.230554	0.1367	0.09177	1.68655	0.00e+00	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_2_gene	-0.282330	0.1891	0.13556	-1.49285	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_2_gene	-0.208514	0.1231	0.09046	-1.69343	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_2_gene	0.102537	0.1247	0.41095	0.82231	0.00e+00	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_2_gene	0.126779	0.1339	0.34382	0.94677	0.00e+00	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_3_gene	-0.239569	0.1799	0.18303	-1.33174	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_3_gene	-0.004484	0.1736	0.97939	-0.02583	0.00e+00	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_3_gene	-0.236218	0.3583	0.50979	-0.65922	0.00e+00	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_3_gene	0.014144	0.2068	0.94548	0.06839	1.73e-18	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_3_gene	0.045103	0.1634	0.78249	0.27609	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_3_gene	-0.160904	0.1829	0.37913	-0.87960	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_3_gene	0.053677	0.3000	0.85798	0.17895	0.00e+00	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_3_gene	-0.088938	0.1727	0.60665	-0.51491	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_3_gene	0.276792	0.1739	0.11156	1.59162	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_3_gene	0.018119	0.1683	0.91427	0.10766	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_3_gene	0.112486	0.1585	0.47789	0.70977	0.00e+00	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_3_gene	-0.130952	0.1879	0.48596	-0.69681	0.00e+00	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_3_gene	-0.325057	0.2599	0.21119	-1.25053	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_3_gene	-0.037656	0.1693	0.82398	-0.22244	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_3_gene	0.007360	0.1714	0.96575	0.04295	-8.67e-19	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_3_gene	0.094286	0.1840	0.60847	0.51230	0.00e+00	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_1_gene	0.277794	0.2126	0.19132	1.30692	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_1_gene	-0.194238	0.1841	0.29140	-1.05522	-2.78e-17	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_2_gene	0.005945	0.1313	0.96388	0.04529	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_2_gene	-0.021599	0.1137	0.84931	-0.19001	0.00e+00	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_3_gene	0.223767	0.1372	0.10304	1.63068	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_3_gene	-0.020827	0.1189	0.86092	-0.17521	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_1_gene	-0.086144	0.0990	0.38446	-0.86980	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_1_gene	-0.064339	0.0922	0.48515	-0.69812	0.00e+00	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_1_gene	-0.056762	0.0821	0.48949	-0.69119	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_2_gene	-0.017711	0.1243	0.88674	-0.14244	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_2_gene	-0.116976	0.1157	0.31202	-1.01113	1.39e-17	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_2_gene	-0.051811	0.1031	0.61531	-0.50255	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_3_gene	0.021142	0.0889	0.81211	0.23772	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_3_gene	0.069953	0.0827	0.39796	0.84537	0.00e+00	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_3_gene	-0.017715	0.0737	0.81017	-0.24023	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_1_gene	0.206383	0.1610	0.19991	1.28204	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_2_gene	0.020222	0.1184	0.86443	0.17075	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_3_gene	0.095524	0.0880	0.27766	1.08574	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_1_gene	0.000650	0.1052	0.99507	0.00618	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_2_gene	0.077929	0.0867	0.36899	0.89848	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_3_gene	-0.084638	0.1759	0.63036	-0.48125	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_1_gene	0.000276	0.1047	0.99790	0.00264	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_1_gene	-0.053677	0.1142	0.63825	-0.47018	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_1_gene	-0.079640	0.1000	0.42607	-0.79602	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_1_gene	-0.058329	0.1825	0.74926	-0.31964	6.94e-18	1
ZBTB39	rs324017	0.223	NAB2	NAB2_1_gene	0.021062	0.0944	0.82345	0.22313	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_2_gene	-0.006791	0.1311	0.95869	-0.05180	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_2_gene	0.184691	0.1429	0.19638	1.29217	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_2_gene	-0.168398	0.1253	0.17891	-1.34436	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_2_gene	-0.223170	0.2285	0.32877	-0.97672	0.00e+00	1
ZBTB39	rs324017	0.223	NAB2	NAB2_2_gene	-0.071793	0.1182	0.54363	-0.60740	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_3_gene	0.113493	0.1321	0.39026	0.85925	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_3_gene	0.223089	0.1440	0.12144	1.54913	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_3_gene	0.093275	0.1262	0.46004	0.73886	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_3_gene	0.302396	0.2302	0.18908	1.31356	0.00e+00	1
ZBTB39	rs324017	0.223	NAB2	NAB2_3_gene	0.219208	0.1191	0.06566	1.84127	0.00e+00	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_1_gene	-0.247822	0.1747	0.15623	-1.41816	0.00e+00	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_2_gene	-0.299492	0.4473	0.50321	-0.66951	0.00e+00	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_3_gene	-0.206575	0.2890	0.47482	-0.71474	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_1_gene	0.039758	0.2283	0.86178	0.17412	0.00e+00	1
GNL3	rs10933	0.882	PBRM1	PBRM1_1_gene	-0.091281	0.2367	0.69978	-0.38564	0.00e+00	1
NEK4	rs10933	0.230	PBRM1	PBRM1_1_gene	-0.315525	0.2262	0.16309	-1.39504	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_1_gene	0.225559	0.2301	0.32694	0.98043	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_1_gene	-0.196379	0.2745	0.47444	-0.71534	0.00e+00	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_1_gene	-0.134174	0.2341	0.56663	-0.57308	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_1_gene	0.268953	0.2351	0.25275	1.14386	0.00e+00	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_1_gene	-0.072641	0.1906	0.70316	-0.38109	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_2_gene	-0.245159	0.1641	0.13523	-1.49411	0.00e+00	1
GNL3	rs10933	0.882	PBRM1	PBRM1_2_gene	0.113406	0.1701	0.50508	0.66658	-1.39e-17	1
NEK4	rs10933	0.230	PBRM1	PBRM1_2_gene	-0.174052	0.1626	0.28447	-1.07048	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_2_gene	0.147996	0.1654	0.37088	0.89494	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_2_gene	0.124406	0.1973	0.52844	0.63045	0.00e+00	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_2_gene	-0.002796	0.1683	0.98674	-0.01662	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_2_gene	-0.107967	0.1690	0.52302	-0.63875	0.00e+00	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_2_gene	-0.143934	0.1370	0.29348	-1.05066	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_3_gene	0.133471	0.1802	0.45882	0.74087	0.00e+00	1
GNL3	rs10933	0.882	PBRM1	PBRM1_3_gene	-0.101766	0.1868	0.58584	-0.54492	1.39e-17	1
NEK4	rs10933	0.230	PBRM1	PBRM1_3_gene	0.208078	0.1785	0.24373	1.16590	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_3_gene	-0.257060	0.1815	0.15676	-1.41634	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_3_gene	0.492397	0.2165	0.02298	2.27469	5.55e-17	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_3_gene	-0.146657	0.1847	0.42729	-0.79393	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_3_gene	0.214689	0.1855	0.24725	1.15724	-2.78e-17	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_3_gene	0.030564	0.1504	0.83898	0.20322	3.47e-18	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_1_gene	0.023992	0.0896	0.78896	0.26768	-3.47e-18	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_1_gene	-0.042823	0.0881	0.62687	-0.48618	0.00e+00	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_1_gene	-0.068355	0.0921	0.45802	-0.74218	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_1_gene	-0.040990	0.0787	0.60260	-0.52070	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_1_gene	-0.065265	0.0860	0.44795	-0.75892	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_1_gene	-0.027349	0.0852	0.74816	-0.32109	0.00e+00	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_2_gene	0.017435	0.0735	0.81247	0.23726	0.00e+00	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_2_gene	-0.032960	0.0722	0.64812	-0.45641	0.00e+00	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_2_gene	-0.059590	0.0755	0.43006	-0.78917	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_2_gene	0.051105	0.0645	0.42849	0.79187	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_2_gene	-0.011562	0.0705	0.86976	-0.16397	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_2_gene	0.007160	0.0698	0.91835	0.10252	0.00e+00	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_3_gene	-0.067450	0.0748	0.36703	-0.90215	0.00e+00	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_3_gene	-0.051957	0.0735	0.47955	-0.70710	6.94e-18	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_3_gene	-0.084292	0.0768	0.27264	-1.09717	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_3_gene	0.007330	0.0657	0.91114	0.11161	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_3_gene	0.046230	0.0717	0.51938	0.64437	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_3_gene	0.008965	0.0711	0.89962	0.12616	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_1_gene	0.015342	0.0804	0.84873	0.19075	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_1_gene	0.107620	0.0782	0.16881	1.37630	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_1_gene	0.019332	0.1311	0.88280	0.14743	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_2_gene	-0.024703	0.1046	0.81332	-0.23617	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_2_gene	0.078572	0.1017	0.43987	0.77250	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_2_gene	0.079042	0.1705	0.64301	0.46354	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_3_gene	0.002569	0.0962	0.97869	0.02672	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_3_gene	-0.078380	0.0935	0.40192	-0.83829	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_3_gene	-0.123283	0.1567	0.43162	-0.78651	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_1_gene	0.079346	0.0814	0.32977	0.97470	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_2_gene	0.039090	0.0935	0.67578	0.41827	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_3_gene	0.060026	0.1219	0.62240	0.49250	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_1_gene	-0.035356	0.1238	0.77528	-0.28550	0.00e+00	1
NAB2	rs324015	0.439	STAT6	STAT6_1_gene	0.030111	0.1350	0.82358	0.22296	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_1_gene	-0.147677	0.1183	0.21212	-1.24797	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_1_gene	-0.028682	0.2159	0.89431	-0.13287	-3.47e-18	1
ZBTB39	rs324015	0.223	STAT6	STAT6_1_gene	-0.062310	0.1117	0.57684	-0.55805	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_2_gene	0.074952	0.1028	0.46582	0.72937	0.00e+00	1
NAB2	rs324015	0.439	STAT6	STAT6_2_gene	0.030190	0.1121	0.78765	0.26938	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_2_gene	-0.016339	0.0982	0.86789	-0.16635	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_2_gene	0.334109	0.1791	0.06213	1.86590	0.00e+00	1
ZBTB39	rs324015	0.223	STAT6	STAT6_2_gene	-0.097349	0.0927	0.29346	-1.05071	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_3_gene	0.003193	0.0964	0.97359	0.03311	4.34e-19	1
NAB2	rs324015	0.439	STAT6	STAT6_3_gene	-0.033556	0.1052	0.74971	-0.31905	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_3_gene	-0.020534	0.0922	0.82373	-0.22277	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_3_gene	-0.211997	0.1681	0.20730	-1.26125	-2.78e-17	1
ZBTB39	rs324015	0.223	STAT6	STAT6_3_gene	0.004667	0.0870	0.95721	0.05366	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_1_gene	0.378321	0.3877	0.32920	0.97586	0.00e+00	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_1_gene	0.100513	0.3614	0.78095	0.27810	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_2_gene	-0.060800	0.1590	0.70227	-0.38229	0.00e+00	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_2_gene	-0.148094	0.1482	0.31784	-0.99903	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_3_gene	-0.046958	0.0735	0.52277	-0.63914	0.00e+00	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_3_gene	-0.062232	0.0685	0.36358	-0.90868	0.00e+00	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_1_gene	0.139057	0.1763	0.43023	0.78888	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_1_gene	-0.051945	0.1260	0.68011	-0.41235	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_1_gene	0.198498	0.1516	0.19058	1.30911	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_1_gene	-0.200493	0.1450	0.16683	-1.38275	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_1_gene	0.203254	0.1481	0.17014	1.37203	2.78e-17	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_2_gene	-0.084310	0.2354	0.72019	-0.35823	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_2_gene	0.062235	0.1682	0.71138	0.37004	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_2_gene	0.259209	0.2024	0.20047	1.28045	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_2_gene	0.508612	0.1935	0.00859	2.62916	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_2_gene	-0.224330	0.1978	0.25681	-1.13415	2.78e-17	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_3_gene	0.093799	0.1925	0.62605	0.48733	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_3_gene	0.018460	0.1375	0.89325	0.13421	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_3_gene	-0.009724	0.1656	0.95318	-0.05872	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_3_gene	-0.130917	0.1583	0.40841	-0.82680	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_3_gene	-0.090456	0.1618	0.57612	-0.55911	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_1_gene	-0.252057	0.2245	0.26156	-1.12288	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_1_gene	-0.206613	0.1513	0.17211	-1.36572	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_1_gene	-0.243815	0.1725	0.15756	-1.41360	0.00e+00	1
CA14	rs2027349	0.138	VPS45	VPS45_1_gene	0.095599	0.1824	0.60032	0.52398	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_1_gene	-0.020033	0.1782	0.91049	-0.11243	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_1_gene	0.075822	0.2786	0.78551	0.27216	0.00e+00	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_1_gene	0.261521	0.1641	0.11099	1.59412	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_1_gene	-0.117106	0.1762	0.50629	-0.66469	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_1_gene	-0.047683	0.1630	0.76983	-0.29261	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_1_gene	0.072066	0.1687	0.66935	0.42708	0.00e+00	1
VPS45	rs2027349	0.492	VPS45	VPS45_1_gene	-0.043631	0.1614	0.78688	-0.27038	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_2_gene	0.088746	0.0894	0.32119	0.99215	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_2_gene	0.109603	0.0603	0.06906	1.81854	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_2_gene	0.109935	0.0687	0.10974	1.59973	1.39e-17	1
CA14	rs2027349	0.138	VPS45	VPS45_2_gene	0.044225	0.0727	0.54300	0.60833	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_2_gene	0.084476	0.0710	0.23413	1.18998	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_2_gene	-0.124238	0.1110	0.26307	-1.11935	-1.39e-17	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_2_gene	-0.034524	0.0654	0.59754	-0.52798	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_2_gene	0.000727	0.0702	0.99174	0.01036	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_2_gene	-0.076907	0.0649	0.23624	-1.18464	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_2_gene	-0.038630	0.0672	0.56563	-0.57454	0.00e+00	1
VPS45	rs2027349	0.492	VPS45	VPS45_2_gene	-0.022299	0.0643	0.72876	-0.34680	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_3_gene	0.194891	0.2277	0.39218	0.85578	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_3_gene	0.144290	0.1535	0.34726	0.94004	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_3_gene	-0.114827	0.1750	0.51179	-0.65612	0.00e+00	1
CA14	rs2027349	0.138	VPS45	VPS45_3_gene	0.052518	0.1851	0.77663	0.28374	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_3_gene	0.286018	0.1807	0.11356	1.58277	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_3_gene	-0.435798	0.2825	0.12305	-1.54246	-5.55e-17	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_3_gene	-0.113551	0.1665	0.49522	-0.68210	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_3_gene	0.078146	0.1787	0.66198	0.43721	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_3_gene	-0.147333	0.1653	0.37281	-0.89133	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_3_gene	0.326101	0.1711	0.05674	1.90591	0.00e+00	1
VPS45	rs2027349	0.492	VPS45	VPS45_3_gene	-0.208142	0.1637	0.20355	-1.27173	2.78e-17	1

ash estimated mixture proportions and corresponding intervals:

pi	interval_a	interval_b
1	0	0

---

ash on 500 kb cis genes

ash_on_scttest(summary_per_gene,full_genes.500kb.expanded,'gRNA')

495 data points:

cisGene	SNP	percentage	locus	gRNA	ttest.beta	ttest.se	ttest.pval	zscore	ash.beta	lfsr
APOPT1	rs7148456	0.855	BAG5	BAG5_1_gene	-0.021439	0.0944	0.82033	-0.22713	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_1_gene	-0.104670	0.0962	0.27643	-1.08855	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_1_gene	-0.054603	0.2143	0.79886	-0.25484	0.00e+00	1
EIF5	rs7148456	0.996	BAG5	BAG5_1_gene	-0.127583	0.1352	0.34548	-0.94350	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_1_gene	-0.012855	0.1134	0.90977	-0.11333	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_1_gene	-0.070932	0.0935	0.44791	-0.75898	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_1_gene	0.028782	0.1029	0.77970	0.27973	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_1_gene	-0.037868	0.1055	0.71979	-0.35877	0.00e+00	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_1_gene	0.065409	0.0940	0.48678	0.69550	0.00e+00	1
APOPT1	rs7148456	0.855	BAG5	BAG5_2_gene	0.257083	0.0948	0.00670	2.71291	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_2_gene	-0.081595	0.0966	0.39854	-0.84433	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_2_gene	-0.092190	0.2153	0.66856	-0.42815	0.00e+00	1
EIF5	rs7148456	0.996	BAG5	BAG5_2_gene	-0.099494	0.1359	0.46414	-0.73213	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_2_gene	0.107367	0.1140	0.34626	0.94199	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_2_gene	-0.091085	0.0939	0.33217	-0.96988	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_2_gene	0.047616	0.1034	0.64519	0.46050	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_2_gene	-0.027456	0.1061	0.79577	-0.25884	3.47e-18	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_2_gene	-0.167572	0.0945	0.07620	-1.77368	0.00e+00	1
APOPT1	rs7148456	0.855	BAG5	BAG5_3_gene	0.033054	0.1177	0.77892	0.28075	0.00e+00	1
BAG5	rs7148456	0.472	BAG5	BAG5_3_gene	0.083466	0.1200	0.48658	0.69582	0.00e+00	1
CKB	rs7148456	1.000	BAG5	BAG5_3_gene	0.153230	0.2673	0.56644	0.57335	0.00e+00	1
EIF5	rs7148456	0.996	BAG5	BAG5_3_gene	-0.219029	0.1687	0.19413	-1.29870	0.00e+00	1
KLC1	rs7148456	0.844	BAG5	BAG5_3_gene	0.271993	0.1414	0.05452	1.92332	0.00e+00	1
MARK3	rs7148456	0.758	BAG5	BAG5_3_gene	-0.027668	0.1166	0.81241	-0.23733	0.00e+00	1
TRMT61A	rs7148456	0.495	BAG5	BAG5_3_gene	-0.303720	0.1283	0.01793	-2.36817	0.00e+00	1
XRCC3	rs7148456	0.305	BAG5	BAG5_3_gene	0.021582	0.1317	0.86980	0.16393	0.00e+00	1
ZFYVE21	rs7148456	0.623	BAG5	BAG5_3_gene	0.019631	0.1173	0.86711	0.16734	0.00e+00	1
CCDC85C	rs12895055	0.325	BCL11B	BCL11B_1_gene	0.085992	0.1414	0.54314	0.60813	0.00e+00	1
CCNK	rs12895055	0.691	BCL11B	BCL11B_1_gene	-0.049221	0.1419	0.72875	-0.34682	-6.94e-18	1
CYP46A1	rs12895055	0.119	BCL11B	BCL11B_1_gene	-0.082655	0.1412	0.55843	-0.58522	0.00e+00	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_1_gene	-0.442592	0.1350	0.00105	-3.27855	-5.55e-17	1
CCDC85C	rs12895055	0.325	BCL11B	BCL11B_2_gene	0.093536	0.0868	0.28141	1.07732	-1.39e-17	1
CCNK	rs12895055	0.691	BCL11B	BCL11B_2_gene	-0.074372	0.0871	0.39346	-0.85346	0.00e+00	1
CYP46A1	rs12895055	0.119	BCL11B	BCL11B_2_gene	-0.055848	0.0867	0.51965	-0.64394	0.00e+00	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_2_gene	-0.019737	0.0830	0.81208	-0.23775	0.00e+00	1
CCDC85C	rs12895055	0.325	BCL11B	BCL11B_3_gene	-0.034056	0.1400	0.80783	-0.24324	0.00e+00	1
CCNK	rs12895055	0.691	BCL11B	BCL11B_3_gene	0.154891	0.1405	0.27032	1.10249	0.00e+00	1
CYP46A1	rs12895055	0.119	BCL11B	BCL11B_3_gene	-0.075244	0.1398	0.59056	-0.53808	0.00e+00	1
SETD3	rs12895055	0.397	BCL11B	BCL11B_3_gene	-0.143051	0.1338	0.28519	-1.06890	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_1_gene	0.213782	0.2262	0.34475	0.94494	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_1_gene	-0.078635	0.2287	0.73104	-0.34377	0.00e+00	1
CIB2	rs7170068	0.567	CHRNA3	CHRNA3_1_gene	0.336392	0.2196	0.12573	1.53152	0.00e+00	1
CRABP1	rs7170068	0.909	CHRNA3	CHRNA3_1_gene	-0.479495	2.2325	0.82995	-0.21478	0.00e+00	1
CTSH	rs7170068	0.107	CHRNA3	CHRNA3_1_gene	0.115967	0.2267	0.60904	0.51149	0.00e+00	1
IDH3A	rs7170068	0.472	CHRNA3	CHRNA3_1_gene	-0.412163	0.2228	0.06439	-1.85004	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_1_gene	-0.010054	0.2147	0.96266	-0.04682	0.00e+00	1
MORF4L1	rs7170068	1.000	CHRNA3	CHRNA3_1_gene	-0.143651	0.1859	0.43982	-0.77258	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_1_gene	0.333663	0.2064	0.10605	1.61658	0.00e+00	1
WDR61	rs7170068	0.770	CHRNA3	CHRNA3_1_gene	0.005478	0.2001	0.97816	0.02737	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_2_gene	0.118609	0.1344	0.37772	0.88221	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_2_gene	-0.152981	0.1359	0.26041	-1.12560	0.00e+00	1
CIB2	rs7170068	0.567	CHRNA3	CHRNA3_2_gene	-0.106046	0.1306	0.41669	-0.81228	0.00e+00	1
CRABP1	rs7170068	0.909	CHRNA3	CHRNA3_2_gene	-1.221694	1.3265	0.35712	-0.92098	0.00e+00	1
CTSH	rs7170068	0.107	CHRNA3	CHRNA3_2_gene	-0.150032	0.1347	0.26547	-1.11372	0.00e+00	1
IDH3A	rs7170068	0.472	CHRNA3	CHRNA3_2_gene	0.102784	0.1324	0.43775	0.77607	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_2_gene	-0.074099	0.1276	0.56145	-0.58074	0.00e+00	1
MORF4L1	rs7170068	1.000	CHRNA3	CHRNA3_2_gene	0.045326	0.1105	0.68169	0.41019	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_2_gene	0.147044	0.1227	0.23073	1.19867	0.00e+00	1
WDR61	rs7170068	0.770	CHRNA3	CHRNA3_2_gene	-0.067126	0.1189	0.57250	-0.56443	0.00e+00	1
ADAMTS7	rs7170068	0.152	CHRNA3	CHRNA3_3_gene	-0.214795	0.1661	0.19613	-1.29289	0.00e+00	1
CHRNA5	rs7170068	0.301	CHRNA3	CHRNA3_3_gene	0.009821	0.1680	0.95338	0.05846	0.00e+00	1
CIB2	rs7170068	0.567	CHRNA3	CHRNA3_3_gene	-0.239595	0.1613	0.13756	-1.48527	-2.78e-17	1
CRABP1	rs7170068	0.909	CHRNA3	CHRNA3_3_gene	-1.667713	1.6393	0.30908	-1.01730	0.00e+00	1
CTSH	rs7170068	0.107	CHRNA3	CHRNA3_3_gene	-0.215842	0.1665	0.19488	-1.29652	0.00e+00	1
IDH3A	rs7170068	0.472	CHRNA3	CHRNA3_3_gene	-0.059025	0.1637	0.71843	-0.36059	0.00e+00	1
IREB2	rs7170068	0.500	CHRNA3	CHRNA3_3_gene	0.282164	0.1576	0.07353	1.79005	0.00e+00	1
MORF4L1	rs7170068	1.000	CHRNA3	CHRNA3_3_gene	-0.095480	0.1366	0.48447	-0.69919	0.00e+00	1
PSMA4	rs7170068	0.999	CHRNA3	CHRNA3_3_gene	-0.147882	0.1516	0.32944	-0.97537	0.00e+00	1
WDR61	rs7170068	0.770	CHRNA3	CHRNA3_3_gene	0.016278	0.1470	0.91182	0.11075	0.00e+00	1
FAM114A2	rs520843	0.371	GALNT10	GALNT10_1_gene	-0.134106	0.0988	0.17461	-1.35780	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_1_gene	-0.068274	0.1000	0.49486	-0.68267	0.00e+00	1
GRIA1	rs520843	0.291	GALNT10	GALNT10_1_gene	0.021920	0.1157	0.84978	0.18942	0.00e+00	1
LARP1	rs520843	0.829	GALNT10	GALNT10_1_gene	0.038467	0.0998	0.69987	0.38553	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_1_gene	0.133326	0.0960	0.16487	1.38916	0.00e+00	1
FAM114A2	rs520843	0.371	GALNT10	GALNT10_2_gene	-0.013318	0.1030	0.89710	-0.12933	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_2_gene	-0.036104	0.1042	0.72912	-0.34633	0.00e+00	1
GRIA1	rs520843	0.291	GALNT10	GALNT10_2_gene	0.096223	0.1206	0.42506	0.79776	0.00e+00	1
LARP1	rs520843	0.829	GALNT10	GALNT10_2_gene	0.085390	0.1040	0.41164	0.82110	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_2_gene	0.130798	0.1000	0.19115	1.30742	0.00e+00	1
FAM114A2	rs520843	0.371	GALNT10	GALNT10_3_gene	-0.127825	0.0809	0.11430	-1.57953	0.00e+00	1
GALNT10	rs520843	0.132	GALNT10	GALNT10_3_gene	0.052448	0.0820	0.52222	0.63999	0.00e+00	1
GRIA1	rs520843	0.291	GALNT10	GALNT10_3_gene	-0.109387	0.0948	0.24869	-1.15372	0.00e+00	1
LARP1	rs520843	0.829	GALNT10	GALNT10_3_gene	0.042335	0.0818	0.60463	0.51780	0.00e+00	1
SAP30L	rs520843	0.294	GALNT10	GALNT10_3_gene	0.051396	0.0787	0.51355	0.65339	6.94e-18	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_1_gene	0.012590	0.1101	0.90897	0.11434	0.00e+00	1
BOLA2B	rs12716973	0.146	KCTD13	KCTD13_1_gene	-0.231949	0.1014	0.02219	-2.28803	0.00e+00	1
CD2BP2	rs12716973	0.799	KCTD13	KCTD13_1_gene	0.063929	0.1031	0.53506	0.62036	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_1_gene	-0.042871	0.1062	0.68651	-0.40363	0.00e+00	1
CORO1A	rs12716973	0.316	KCTD13	KCTD13_1_gene	-0.172248	0.1163	0.13881	-1.48057	0.00e+00	1
DCTPP1	rs12716973	0.768	KCTD13	KCTD13_1_gene	-0.095009	0.1669	0.56924	-0.56922	0.00e+00	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_1_gene	0.000295	0.2193	0.99893	0.00135	0.00e+00	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_1_gene	-0.052172	0.1266	0.68019	-0.41224	0.00e+00	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_1_gene	-0.016316	0.1000	0.87035	-0.16322	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_1_gene	-0.187460	0.1119	0.09399	-1.67515	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_1_gene	0.022581	0.1835	0.90209	0.12303	0.00e+00	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_1_gene	-0.079525	0.1057	0.45184	-0.75244	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_1_gene	-0.034502	0.1065	0.74587	-0.32411	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_1_gene	0.063456	0.1030	0.53779	0.61621	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_1_gene	0.061396	0.0970	0.52672	0.63309	-6.94e-18	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_1_gene	0.055258	0.1150	0.63090	0.48050	0.00e+00	1
QPRT	rs12716973	0.426	KCTD13	KCTD13_1_gene	-0.091156	0.2230	0.68279	-0.40869	0.00e+00	1
SEPT1	rs12716973	0.201	KCTD13	KCTD13_1_gene	-0.086679	0.1077	0.42089	-0.80497	0.00e+00	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_1_gene	0.089667	0.1591	0.57304	0.56364	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_1_gene	0.110788	0.1036	0.28484	1.06965	0.00e+00	1
TBC1D10B	rs12716973	0.302	KCTD13	KCTD13_1_gene	-0.030701	0.1046	0.76907	-0.29361	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_1_gene	0.007900	0.1049	0.93996	0.07533	0.00e+00	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_1_gene	-0.108128	0.1126	0.33702	-0.96019	0.00e+00	1
ZNF48	rs12716973	0.571	KCTD13	KCTD13_1_gene	0.022253	0.1089	0.83812	0.20431	0.00e+00	1
ZNF771	rs12716973	0.548	KCTD13	KCTD13_1_gene	-0.072673	0.1094	0.50665	-0.66413	0.00e+00	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_2_gene	0.108078	0.1309	0.40911	0.82556	0.00e+00	1
BOLA2B	rs12716973	0.146	KCTD13	KCTD13_2_gene	0.124047	0.1206	0.30380	1.02847	1.39e-17	1
CD2BP2	rs12716973	0.799	KCTD13	KCTD13_2_gene	0.146057	0.1225	0.23330	1.19210	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_2_gene	-0.086724	0.1263	0.49232	-0.68669	0.00e+00	1
CORO1A	rs12716973	0.316	KCTD13	KCTD13_2_gene	0.136180	0.1384	0.32507	0.98423	0.00e+00	1
DCTPP1	rs12716973	0.768	KCTD13	KCTD13_2_gene	0.102369	0.1985	0.60604	0.51578	0.00e+00	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_2_gene	-0.106476	0.2607	0.68303	-0.40836	-1.39e-17	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_2_gene	0.044530	0.1505	0.76733	0.29590	0.00e+00	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_2_gene	-0.063099	0.1189	0.59556	-0.53085	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_2_gene	0.288110	0.1330	0.03040	2.16568	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_2_gene	-0.234664	0.2182	0.28229	-1.07534	-2.78e-17	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_2_gene	0.185851	0.1256	0.13919	1.47913	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_2_gene	-0.095649	0.1266	0.44989	-0.75568	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_2_gene	-0.132721	0.1224	0.27845	-1.08398	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_2_gene	-0.005190	0.1153	0.96411	-0.04500	0.00e+00	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_2_gene	0.230554	0.1367	0.09177	1.68655	0.00e+00	1
QPRT	rs12716973	0.426	KCTD13	KCTD13_2_gene	0.540454	0.2651	0.04154	2.03881	0.00e+00	1
SEPT1	rs12716973	0.201	KCTD13	KCTD13_2_gene	0.187097	0.1280	0.14397	1.46149	2.78e-17	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_2_gene	-0.282330	0.1891	0.13556	-1.49285	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_2_gene	-0.208514	0.1231	0.09046	-1.69343	0.00e+00	1
TBC1D10B	rs12716973	0.302	KCTD13	KCTD13_2_gene	-0.010263	0.1243	0.93422	-0.08254	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_2_gene	0.102537	0.1247	0.41095	0.82231	0.00e+00	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_2_gene	0.126779	0.1339	0.34382	0.94677	0.00e+00	1
ZNF48	rs12716973	0.571	KCTD13	KCTD13_2_gene	-0.146968	0.1295	0.25647	-1.13495	0.00e+00	1
ZNF771	rs12716973	0.548	KCTD13	KCTD13_2_gene	-0.199695	0.1301	0.12485	-1.53509	0.00e+00	1
ALDOA	rs12716973	0.494	KCTD13	KCTD13_3_gene	-0.239569	0.1799	0.18303	-1.33174	0.00e+00	1
BOLA2B	rs12716973	0.146	KCTD13	KCTD13_3_gene	0.050960	0.1658	0.75856	0.30739	0.00e+00	1
CD2BP2	rs12716973	0.799	KCTD13	KCTD13_3_gene	-0.062611	0.1684	0.71008	-0.37177	0.00e+00	1
CDIPT	rs12716973	0.612	KCTD13	KCTD13_3_gene	-0.004484	0.1736	0.97939	-0.02583	0.00e+00	1
CORO1A	rs12716973	0.316	KCTD13	KCTD13_3_gene	-0.112660	0.1902	0.55361	-0.59242	1.39e-17	1
DCTPP1	rs12716973	0.768	KCTD13	KCTD13_3_gene	0.085112	0.2728	0.75504	0.31202	-1.39e-17	1
FAM57B	rs12716973	0.104	KCTD13	KCTD13_3_gene	-0.236218	0.3583	0.50979	-0.65922	0.00e+00	1
HIRIP3	rs12716973	0.673	KCTD13	KCTD13_3_gene	0.014144	0.2068	0.94548	0.06839	1.73e-18	1
INO80E	rs12716973	0.723	KCTD13	KCTD13_3_gene	0.045103	0.1634	0.78249	0.27609	0.00e+00	1
KCTD13	rs12716973	0.218	KCTD13	KCTD13_3_gene	-0.160904	0.1829	0.37913	-0.87960	0.00e+00	1
KIF22	rs12716973	0.764	KCTD13	KCTD13_3_gene	0.053677	0.3000	0.85798	0.17895	0.00e+00	1
MAPK3	rs12716973	0.569	KCTD13	KCTD13_3_gene	-0.088938	0.1727	0.60665	-0.51491	0.00e+00	1
MAZ	rs12716973	0.881	KCTD13	KCTD13_3_gene	0.276792	0.1739	0.11156	1.59162	0.00e+00	1
PAGR1	rs12716973	0.203	KCTD13	KCTD13_3_gene	0.018119	0.1683	0.91427	0.10766	0.00e+00	1
PPP4C	rs12716973	0.977	KCTD13	KCTD13_3_gene	0.112486	0.1585	0.47789	0.70977	0.00e+00	1
PRRT2	rs12716973	0.145	KCTD13	KCTD13_3_gene	-0.130952	0.1879	0.48596	-0.69681	0.00e+00	1
QPRT	rs12716973	0.426	KCTD13	KCTD13_3_gene	-0.575379	0.3644	0.11442	-1.57903	0.00e+00	1
SEPT1	rs12716973	0.201	KCTD13	KCTD13_3_gene	-0.307133	0.1759	0.08091	-1.74591	0.00e+00	1
SEZ6L2	rs12716973	0.114	KCTD13	KCTD13_3_gene	-0.325057	0.2599	0.21119	-1.25053	0.00e+00	1
TAOK2	rs12716973	0.231	KCTD13	KCTD13_3_gene	-0.037656	0.1693	0.82398	-0.22244	0.00e+00	1
TBC1D10B	rs12716973	0.302	KCTD13	KCTD13_3_gene	-0.170261	0.1709	0.31907	-0.99651	0.00e+00	1
TMEM219	rs12716973	0.870	KCTD13	KCTD13_3_gene	0.007360	0.1714	0.96575	0.04295	-8.67e-19	1
YPEL3	rs12716973	0.106	KCTD13	KCTD13_3_gene	0.094286	0.1840	0.60847	0.51230	0.00e+00	1
ZNF48	rs12716973	0.571	KCTD13	KCTD13_3_gene	-0.182253	0.1780	0.30587	-1.02406	0.00e+00	1
ZNF771	rs12716973	0.548	KCTD13	KCTD13_3_gene	-0.152193	0.1788	0.39477	-0.85110	0.00e+00	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_1_gene	0.277794	0.2126	0.19132	1.30692	0.00e+00	1
PUS7	rs2192932	0.269	KMT2E	KMT2E_1_gene	0.039546	0.1870	0.83254	0.21146	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_1_gene	-0.194238	0.1841	0.29140	-1.05522	-2.78e-17	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_2_gene	0.005945	0.1313	0.96388	0.04529	0.00e+00	1
PUS7	rs2192932	0.269	KMT2E	KMT2E_2_gene	0.026215	0.1155	0.82042	0.22702	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_2_gene	-0.021599	0.1137	0.84931	-0.19001	0.00e+00	1
KMT2E	rs2192932	0.841	KMT2E	KMT2E_3_gene	0.223767	0.1372	0.10304	1.63068	0.00e+00	1
PUS7	rs2192932	0.269	KMT2E	KMT2E_3_gene	-0.105881	0.1207	0.38058	-0.87693	0.00e+00	1
SRPK2	rs2192932	0.838	KMT2E	KMT2E_3_gene	-0.020827	0.1189	0.86092	-0.17521	0.00e+00	1
APOPT1	rs3861678	0.855	LINC00637	LINC00637_1_gene	0.150316	0.0824	0.06815	1.82457	0.00e+00	1
BAG5	rs3861678	0.472	LINC00637	LINC00637_1_gene	0.100202	0.0840	0.23277	1.19344	-1.39e-17	1
CKB	rs3861678	1.000	LINC00637	LINC00637_1_gene	0.046096	0.1871	0.80540	0.24638	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_1_gene	-0.086144	0.0990	0.38446	-0.86980	0.00e+00	1
MARK3	rs3861678	0.758	LINC00637	LINC00637_1_gene	-0.084300	0.0816	0.30163	-1.03308	-1.39e-17	1
TRMT61A	rs3861678	0.495	LINC00637	LINC00637_1_gene	0.018478	0.0898	0.83707	0.20566	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_1_gene	-0.064339	0.0922	0.48515	-0.69812	0.00e+00	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_1_gene	-0.056762	0.0821	0.48949	-0.69119	0.00e+00	1
APOPT1	rs3861678	0.855	LINC00637	LINC00637_2_gene	0.008486	0.1035	0.93464	0.08201	0.00e+00	1
BAG5	rs3861678	0.472	LINC00637	LINC00637_2_gene	0.048176	0.1054	0.64770	0.45700	0.00e+00	1
CKB	rs3861678	1.000	LINC00637	LINC00637_2_gene	-0.166284	0.2349	0.47898	-0.70801	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_2_gene	-0.017711	0.1243	0.88674	-0.14244	0.00e+00	1
MARK3	rs3861678	0.758	LINC00637	LINC00637_2_gene	0.038189	0.1025	0.70936	0.37275	0.00e+00	1
TRMT61A	rs3861678	0.495	LINC00637	LINC00637_2_gene	-0.053394	0.1128	0.63596	-0.47339	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_2_gene	-0.116976	0.1157	0.31202	-1.01113	1.39e-17	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_2_gene	-0.051811	0.1031	0.61531	-0.50255	0.00e+00	1
APOPT1	rs3861678	0.855	LINC00637	LINC00637_3_gene	-0.021325	0.0740	0.77325	-0.28815	0.00e+00	1
BAG5	rs3861678	0.472	LINC00637	LINC00637_3_gene	-0.078079	0.0754	0.30043	-1.03565	0.00e+00	1
CKB	rs3861678	1.000	LINC00637	LINC00637_3_gene	-0.012153	0.1680	0.94234	-0.07234	0.00e+00	1
KLC1	rs3861678	0.844	LINC00637	LINC00637_3_gene	0.021142	0.0889	0.81211	0.23772	0.00e+00	1
MARK3	rs3861678	0.758	LINC00637	LINC00637_3_gene	0.087672	0.0733	0.23153	1.19663	0.00e+00	1
TRMT61A	rs3861678	0.495	LINC00637	LINC00637_3_gene	0.052818	0.0807	0.51267	0.65474	0.00e+00	1
XRCC3	rs3861678	0.305	LINC00637	LINC00637_3_gene	0.069953	0.0827	0.39796	0.84537	0.00e+00	1
ZFYVE21	rs3861678	0.623	LINC00637	LINC00637_3_gene	-0.017715	0.0737	0.81017	-0.24023	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_1_gene	0.206383	0.1610	0.19991	1.28204	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_2_gene	0.020222	0.1184	0.86443	0.17075	0.00e+00	1
SNX19	rs7936858	0.206	LOC100507431	LOC100507431_3_gene	0.095524	0.0880	0.27766	1.08574	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_1_gene	0.000650	0.1052	0.99507	0.00618	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_2_gene	0.077929	0.0867	0.36899	0.89848	0.00e+00	1
TBC1D5	rs17200916	0.297	LOC105376975	LOC105376975_3_gene	-0.084638	0.1759	0.63036	-0.48125	0.00e+00	1
BAZ2A	rs324017	0.629	NAB2	NAB2_1_gene	0.063612	0.0947	0.50198	0.67145	0.00e+00	1
DCTN2	rs324017	0.984	NAB2	NAB2_1_gene	-0.030533	0.0931	0.74302	-0.32788	0.00e+00	1
DDIT3	rs324017	0.594	NAB2	NAB2_1_gene	0.006797	0.3277	0.98345	0.02074	0.00e+00	1
KIF5A	rs324017	0.111	NAB2	NAB2_1_gene	-0.037380	0.1132	0.74135	-0.33009	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_1_gene	0.000276	0.1047	0.99790	0.00264	0.00e+00	1
MARS	rs324017	0.764	NAB2	NAB2_1_gene	0.009086	0.1128	0.93581	0.08054	0.00e+00	1
MBD6	rs324017	0.267	NAB2	NAB2_1_gene	-0.076799	0.0968	0.42738	-0.79377	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_1_gene	-0.053677	0.1142	0.63825	-0.47018	0.00e+00	1
NACA	rs324017	1.000	NAB2	NAB2_1_gene	-0.042797	0.0624	0.49312	-0.68542	0.00e+00	1
PIP4K2C	rs324017	0.147	NAB2	NAB2_1_gene	-0.023702	0.0957	0.80431	-0.24779	0.00e+00	1
PRIM1	rs324017	0.389	NAB2	NAB2_1_gene	-0.162705	0.1128	0.14932	-1.44225	0.00e+00	1
PTGES3	rs324017	0.998	NAB2	NAB2_1_gene	0.155034	0.0995	0.11923	1.55838	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_1_gene	-0.079640	0.1000	0.42607	-0.79602	0.00e+00	1
RBMS2	rs324017	0.188	NAB2	NAB2_1_gene	0.127863	0.0949	0.17796	1.34731	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_1_gene	-0.058329	0.1825	0.74926	-0.31964	6.94e-18	1
ZBTB39	rs324017	0.223	NAB2	NAB2_1_gene	0.021062	0.0944	0.82345	0.22313	0.00e+00	1
BAZ2A	rs324017	0.629	NAB2	NAB2_2_gene	-0.154054	0.1186	0.19410	-1.29877	0.00e+00	1
DCTN2	rs324017	0.984	NAB2	NAB2_2_gene	-0.099607	0.1166	0.39301	-0.85427	0.00e+00	1
DDIT3	rs324017	0.594	NAB2	NAB2_2_gene	-0.297647	0.4104	0.46830	-0.72533	0.00e+00	1
KIF5A	rs324017	0.111	NAB2	NAB2_2_gene	0.002397	0.1418	0.98652	0.01690	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_2_gene	-0.006791	0.1311	0.95869	-0.05180	0.00e+00	1
MARS	rs324017	0.764	NAB2	NAB2_2_gene	-0.053598	0.1413	0.70440	-0.37941	0.00e+00	1
MBD6	rs324017	0.267	NAB2	NAB2_2_gene	-0.111535	0.1212	0.35731	-0.92061	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_2_gene	0.184691	0.1429	0.19638	1.29217	0.00e+00	1
NACA	rs324017	1.000	NAB2	NAB2_2_gene	0.050435	0.0782	0.51894	0.64504	-6.94e-18	1
PIP4K2C	rs324017	0.147	NAB2	NAB2_2_gene	0.057021	0.1198	0.63406	0.47606	0.00e+00	1
PRIM1	rs324017	0.389	NAB2	NAB2_2_gene	-0.045988	0.1413	0.74486	-0.32545	0.00e+00	1
PTGES3	rs324017	0.998	NAB2	NAB2_2_gene	-0.042081	0.1246	0.73562	-0.33768	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_2_gene	-0.168398	0.1253	0.17891	-1.34436	0.00e+00	1
RBMS2	rs324017	0.188	NAB2	NAB2_2_gene	-0.005250	0.1189	0.96477	-0.04417	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_2_gene	-0.223170	0.2285	0.32877	-0.97672	0.00e+00	1
ZBTB39	rs324017	0.223	NAB2	NAB2_2_gene	-0.071793	0.1182	0.54363	-0.60740	0.00e+00	1
BAZ2A	rs324017	0.629	NAB2	NAB2_3_gene	-0.147812	0.1195	0.21629	-1.23667	0.00e+00	1
DCTN2	rs324017	0.984	NAB2	NAB2_3_gene	0.098309	0.1175	0.40280	0.83673	0.00e+00	1
DDIT3	rs324017	0.594	NAB2	NAB2_3_gene	0.272939	0.4135	0.50925	0.66007	0.00e+00	1
KIF5A	rs324017	0.111	NAB2	NAB2_3_gene	0.246971	0.1428	0.08387	1.72910	0.00e+00	1
LRP1	rs324017	0.342	NAB2	NAB2_3_gene	0.113493	0.1321	0.39026	0.85925	0.00e+00	1
MARS	rs324017	0.764	NAB2	NAB2_3_gene	0.123930	0.1423	0.38397	0.87070	0.00e+00	1
MBD6	rs324017	0.267	NAB2	NAB2_3_gene	-0.084506	0.1221	0.48886	-0.69219	0.00e+00	1
NAB2	rs324017	0.439	NAB2	NAB2_3_gene	0.223089	0.1440	0.12144	1.54913	0.00e+00	1
NACA	rs324017	1.000	NAB2	NAB2_3_gene	-0.024110	0.0788	0.75962	-0.30601	3.47e-18	1
PIP4K2C	rs324017	0.147	NAB2	NAB2_3_gene	0.065403	0.1207	0.58792	0.54190	0.00e+00	1
PRIM1	rs324017	0.389	NAB2	NAB2_3_gene	-0.177492	0.1424	0.21255	-1.24680	0.00e+00	1
PTGES3	rs324017	0.998	NAB2	NAB2_3_gene	-0.186418	0.1255	0.13763	-1.48501	0.00e+00	1
R3HDM2	rs324017	0.216	NAB2	NAB2_3_gene	0.093275	0.1262	0.46004	0.73886	0.00e+00	1
RBMS2	rs324017	0.188	NAB2	NAB2_3_gene	0.158867	0.1197	0.18470	1.32667	0.00e+00	1
SHMT2	rs324017	0.813	NAB2	NAB2_3_gene	0.302396	0.2302	0.18908	1.31356	0.00e+00	1
ZBTB39	rs324017	0.223	NAB2	NAB2_3_gene	0.219208	0.1191	0.06566	1.84127	0.00e+00	1
ATG16L1	rs186132169	0.186	NGEF	NGEF_1_gene	-0.058982	0.1627	0.71691	-0.36262	0.00e+00	1
DGKD	rs186132169	0.164	NGEF	NGEF_1_gene	-0.094977	0.1668	0.56900	-0.56957	0.00e+00	1
EFHD1	rs186132169	0.156	NGEF	NGEF_1_gene	0.481799	0.1994	0.01572	2.41655	0.00e+00	1
EIF4E2	rs186132169	0.914	NGEF	NGEF_1_gene	0.177236	0.1581	0.26229	1.12116	0.00e+00	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_1_gene	-0.247822	0.1747	0.15623	-1.41816	0.00e+00	1
TIGD1	rs186132169	0.191	NGEF	NGEF_1_gene	-0.164145	0.1740	0.34559	-0.94331	0.00e+00	1
ATG16L1	rs186132169	0.186	NGEF	NGEF_2_gene	0.013640	0.4163	0.97386	0.03276	1.73e-18	1
DGKD	rs186132169	0.164	NGEF	NGEF_2_gene	0.538141	0.4267	0.20732	1.26119	0.00e+00	1
EFHD1	rs186132169	0.156	NGEF	NGEF_2_gene	0.307182	0.5106	0.54750	0.60156	0.00e+00	1
EIF4E2	rs186132169	0.914	NGEF	NGEF_2_gene	0.450580	0.4046	0.26549	1.11368	-5.55e-17	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_2_gene	-0.299492	0.4473	0.50321	-0.66951	0.00e+00	1
TIGD1	rs186132169	0.191	NGEF	NGEF_2_gene	-0.006104	0.4454	0.98907	-0.01370	0.00e+00	1
ATG16L1	rs186132169	0.186	NGEF	NGEF_3_gene	0.101579	0.2690	0.70570	0.37767	0.00e+00	1
DGKD	rs186132169	0.164	NGEF	NGEF_3_gene	0.468085	0.2756	0.08956	1.69816	0.00e+00	1
EFHD1	rs186132169	0.156	NGEF	NGEF_3_gene	-0.347306	0.3299	0.29251	-1.05278	0.00e+00	1
EIF4E2	rs186132169	0.914	NGEF	NGEF_3_gene	-0.017393	0.2614	0.94696	-0.06652	0.00e+00	1
GIGYF2	rs186132169	0.625	NGEF	NGEF_3_gene	-0.206575	0.2890	0.47482	-0.71474	0.00e+00	1
TIGD1	rs186132169	0.191	NGEF	NGEF_3_gene	-0.021412	0.2878	0.94069	-0.07440	0.00e+00	1
ALAS1	rs10933	0.484	PBRM1	PBRM1_1_gene	-0.143072	0.2295	0.53300	-0.62349	0.00e+00	1
BAP1	rs10933	0.400	PBRM1	PBRM1_1_gene	0.221635	0.2236	0.32154	0.99142	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_1_gene	0.039758	0.2283	0.86178	0.17412	0.00e+00	1
GLYCTK	rs10933	0.109	PBRM1	PBRM1_1_gene	-0.190579	0.2254	0.39792	-0.84543	0.00e+00	1
GNL3	rs10933	0.882	PBRM1	PBRM1_1_gene	-0.091281	0.2367	0.69978	-0.38564	0.00e+00	1
NEK4	rs10933	0.230	PBRM1	PBRM1_1_gene	-0.315525	0.2262	0.16309	-1.39504	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_1_gene	0.225559	0.2301	0.32694	0.98043	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_1_gene	-0.196379	0.2745	0.47444	-0.71534	0.00e+00	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_1_gene	-0.134174	0.2341	0.56663	-0.57308	0.00e+00	1
PHF7	rs10933	0.149	PBRM1	PBRM1_1_gene	-0.279804	0.2314	0.22665	-1.20924	0.00e+00	1
RFT1	rs10933	0.447	PBRM1	PBRM1_1_gene	0.449767	0.2273	0.04789	1.97904	0.00e+00	1
SFMBT1	rs10933	0.226	PBRM1	PBRM1_1_gene	-0.161380	0.2420	0.50487	-0.66692	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_1_gene	0.268953	0.2351	0.25275	1.14386	0.00e+00	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_1_gene	-0.072641	0.1906	0.70316	-0.38109	0.00e+00	1
TWF2	rs10933	0.574	PBRM1	PBRM1_1_gene	0.182698	0.2328	0.43270	0.78466	0.00e+00	1
WDR82	rs10933	0.683	PBRM1	PBRM1_1_gene	-0.300116	0.2200	0.17269	-1.36387	0.00e+00	1
ALAS1	rs10933	0.484	PBRM1	PBRM1_2_gene	-0.015341	0.1649	0.92590	-0.09300	0.00e+00	1
BAP1	rs10933	0.400	PBRM1	PBRM1_2_gene	-0.132058	0.1607	0.41125	-0.82179	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_2_gene	-0.245159	0.1641	0.13523	-1.49411	0.00e+00	1
GLYCTK	rs10933	0.109	PBRM1	PBRM1_2_gene	-0.089137	0.1620	0.58229	-0.55009	0.00e+00	1
GNL3	rs10933	0.882	PBRM1	PBRM1_2_gene	0.113406	0.1701	0.50508	0.66658	-1.39e-17	1
NEK4	rs10933	0.230	PBRM1	PBRM1_2_gene	-0.174052	0.1626	0.28447	-1.07048	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_2_gene	0.147996	0.1654	0.37088	0.89494	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_2_gene	0.124406	0.1973	0.52844	0.63045	0.00e+00	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_2_gene	-0.002796	0.1683	0.98674	-0.01662	0.00e+00	1
PHF7	rs10933	0.149	PBRM1	PBRM1_2_gene	0.005402	0.1664	0.97410	0.03247	0.00e+00	1
RFT1	rs10933	0.447	PBRM1	PBRM1_2_gene	-0.143932	0.1634	0.37853	-0.88071	0.00e+00	1
SFMBT1	rs10933	0.226	PBRM1	PBRM1_2_gene	-0.170941	0.1739	0.32574	-0.98286	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_2_gene	-0.107967	0.1690	0.52302	-0.63875	0.00e+00	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_2_gene	-0.143934	0.1370	0.29348	-1.05066	0.00e+00	1
TWF2	rs10933	0.574	PBRM1	PBRM1_2_gene	0.132393	0.1674	0.42896	0.79106	0.00e+00	1
WDR82	rs10933	0.683	PBRM1	PBRM1_2_gene	-0.137296	0.1582	0.38550	-0.86791	0.00e+00	1
ALAS1	rs10933	0.484	PBRM1	PBRM1_3_gene	-0.379942	0.1810	0.03583	-2.09963	0.00e+00	1
BAP1	rs10933	0.400	PBRM1	PBRM1_3_gene	-0.019016	0.1764	0.91416	-0.10780	0.00e+00	1
GLT8D1	rs10933	0.612	PBRM1	PBRM1_3_gene	0.133471	0.1802	0.45882	0.74087	0.00e+00	1
GLYCTK	rs10933	0.109	PBRM1	PBRM1_3_gene	-0.105903	0.1779	0.55161	-0.59540	1.39e-17	1
GNL3	rs10933	0.882	PBRM1	PBRM1_3_gene	-0.101766	0.1868	0.58584	-0.54492	1.39e-17	1
NEK4	rs10933	0.230	PBRM1	PBRM1_3_gene	0.208078	0.1785	0.24373	1.16590	0.00e+00	1
NISCH	rs10933	0.473	PBRM1	PBRM1_3_gene	-0.257060	0.1815	0.15676	-1.41634	0.00e+00	1
NT5DC2	rs10933	0.760	PBRM1	PBRM1_3_gene	0.492397	0.2165	0.02298	2.27469	5.55e-17	1
PBRM1	rs10933	0.663	PBRM1	PBRM1_3_gene	-0.146657	0.1847	0.42729	-0.79393	0.00e+00	1
PHF7	rs10933	0.149	PBRM1	PBRM1_3_gene	-0.277179	0.1825	0.12900	-1.51839	0.00e+00	1
RFT1	rs10933	0.447	PBRM1	PBRM1_3_gene	-0.019839	0.1794	0.91195	-0.11058	0.00e+00	1
SFMBT1	rs10933	0.226	PBRM1	PBRM1_3_gene	0.102002	0.1909	0.59321	0.53424	0.00e+00	1
SMIM4	rs10933	0.632	PBRM1	PBRM1_3_gene	0.214689	0.1855	0.24725	1.15724	-2.78e-17	1
SPCS1	rs10933	0.987	PBRM1	PBRM1_3_gene	0.030564	0.1504	0.83898	0.20322	3.47e-18	1
TWF2	rs10933	0.574	PBRM1	PBRM1_3_gene	0.109688	0.1837	0.55051	0.59704	0.00e+00	1
WDR82	rs10933	0.683	PBRM1	PBRM1_3_gene	-0.109113	0.1737	0.52982	-0.62834	0.00e+00	1
ANKHD1	rs4151680	0.261	PCDHA123	PCDHA123_1_gene	-0.078312	0.0869	0.36741	-0.90144	0.00e+00	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_1_gene	0.023992	0.0896	0.78896	0.26768	-3.47e-18	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_1_gene	-0.042823	0.0881	0.62687	-0.48618	0.00e+00	1
HBEGF	rs4151680	0.127	PCDHA123	PCDHA123_1_gene	-0.089196	0.1201	0.45754	-0.74298	0.00e+00	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_1_gene	-0.068355	0.0921	0.45802	-0.74218	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_1_gene	-0.040990	0.0787	0.60260	-0.52070	0.00e+00	1
PCDHB2	rs4151680	0.179	PCDHA123	PCDHA123_1_gene	0.151789	0.0985	0.12352	1.54053	0.00e+00	1
SLC35A4	rs4151680	0.793	PCDHA123	PCDHA123_1_gene	0.008900	0.0898	0.92109	0.09907	0.00e+00	1
SRA1	rs4151680	0.937	PCDHA123	PCDHA123_1_gene	-0.205018	0.1148	0.07424	-1.78561	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_1_gene	-0.065265	0.0860	0.44795	-0.75892	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_1_gene	-0.027349	0.0852	0.74816	-0.32109	0.00e+00	1
ANKHD1	rs4151680	0.261	PCDHA123	PCDHA123_2_gene	-0.058591	0.0712	0.41079	-0.82260	0.00e+00	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_2_gene	0.017435	0.0735	0.81247	0.23726	0.00e+00	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_2_gene	-0.032960	0.0722	0.64812	-0.45641	0.00e+00	1
HBEGF	rs4151680	0.127	PCDHA123	PCDHA123_2_gene	-0.022207	0.0984	0.82152	-0.22561	0.00e+00	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_2_gene	-0.059590	0.0755	0.43006	-0.78917	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_2_gene	0.051105	0.0645	0.42849	0.79187	0.00e+00	1
PCDHB2	rs4151680	0.179	PCDHA123	PCDHA123_2_gene	0.087745	0.0808	0.27754	1.08603	0.00e+00	1
SLC35A4	rs4151680	0.793	PCDHA123	PCDHA123_2_gene	0.030664	0.0737	0.67721	0.41631	0.00e+00	1
SRA1	rs4151680	0.937	PCDHA123	PCDHA123_2_gene	-0.064364	0.0942	0.49434	-0.68349	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_2_gene	-0.011562	0.0705	0.86976	-0.16397	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_2_gene	0.007160	0.0698	0.91835	0.10252	0.00e+00	1
ANKHD1	rs4151680	0.261	PCDHA123	PCDHA123_3_gene	0.067158	0.0725	0.35417	0.92665	0.00e+00	1
HARS2	rs4151680	0.296	PCDHA123	PCDHA123_3_gene	-0.067450	0.0748	0.36703	-0.90215	0.00e+00	1
HARS	rs4151680	0.834	PCDHA123	PCDHA123_3_gene	-0.051957	0.0735	0.47955	-0.70710	6.94e-18	1
HBEGF	rs4151680	0.127	PCDHA123	PCDHA123_3_gene	-0.120170	0.1001	0.23021	-1.20002	0.00e+00	1
IK	rs4151680	0.892	PCDHA123	PCDHA123_3_gene	-0.084292	0.0768	0.27264	-1.09717	0.00e+00	1
NDUFA2	rs4151680	0.970	PCDHA123	PCDHA123_3_gene	0.007330	0.0657	0.91114	0.11161	0.00e+00	1
PCDHB2	rs4151680	0.179	PCDHA123	PCDHA123_3_gene	0.004459	0.0822	0.95676	0.05423	0.00e+00	1
SLC35A4	rs4151680	0.793	PCDHA123	PCDHA123_3_gene	0.110541	0.0749	0.14022	1.47527	0.00e+00	1
SRA1	rs4151680	0.937	PCDHA123	PCDHA123_3_gene	-0.043605	0.0958	0.64910	-0.45505	0.00e+00	1
WDR55	rs4151680	0.361	PCDHA123	PCDHA123_3_gene	0.046230	0.0717	0.51938	0.64437	0.00e+00	1
ZMAT2	rs4151680	0.912	PCDHA123	PCDHA123_3_gene	0.008965	0.0711	0.89962	0.12616	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_1_gene	0.015342	0.0804	0.84873	0.19075	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_1_gene	0.107620	0.0782	0.16881	1.37630	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_1_gene	0.019332	0.1311	0.88280	0.14743	0.00e+00	1
RALGAPB	rs6071578	0.266	PPP1R16B	PPP1R16B_1_gene	0.018099	0.0781	0.81679	0.23169	0.00e+00	1
SNHG11	rs6071578	0.616	PPP1R16B	PPP1R16B_1_gene	0.101865	0.0829	0.21927	1.22867	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_2_gene	-0.024703	0.1046	0.81332	-0.23617	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_2_gene	0.078572	0.1017	0.43987	0.77250	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_2_gene	0.079042	0.1705	0.64301	0.46354	0.00e+00	1
RALGAPB	rs6071578	0.266	PPP1R16B	PPP1R16B_2_gene	-0.110442	0.1016	0.27697	-1.08731	0.00e+00	1
SNHG11	rs6071578	0.616	PPP1R16B	PPP1R16B_2_gene	-0.105777	0.1078	0.32666	-0.98099	0.00e+00	1
ACTR5	rs6071578	0.190	PPP1R16B	PPP1R16B_3_gene	0.002569	0.0962	0.97869	0.02672	0.00e+00	1
DHX35	rs6071578	0.159	PPP1R16B	PPP1R16B_3_gene	-0.078380	0.0935	0.40192	-0.83829	0.00e+00	1
FAM83D	rs6071578	0.271	PPP1R16B	PPP1R16B_3_gene	-0.123283	0.1567	0.43162	-0.78651	0.00e+00	1
RALGAPB	rs6071578	0.266	PPP1R16B	PPP1R16B_3_gene	0.055169	0.0934	0.55472	0.59076	0.00e+00	1
SNHG11	rs6071578	0.616	PPP1R16B	PPP1R16B_3_gene	-0.006999	0.0991	0.94372	-0.07060	8.67e-19	1
ENO1	rs301791	0.999	RERE	RERE_1_gene	0.045807	0.0902	0.61167	0.50773	0.00e+00	1
ERRFI1	rs301791	0.449	RERE	RERE_1_gene	-0.077790	0.0859	0.36532	-0.90539	0.00e+00	1
PARK7	rs301791	1.000	RERE	RERE_1_gene	0.064759	0.0671	0.33435	0.96551	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_1_gene	0.079346	0.0814	0.32977	0.97470	0.00e+00	1
ENO1	rs301791	0.999	RERE	RERE_2_gene	-0.076400	0.1036	0.46072	-0.73774	0.00e+00	1
ERRFI1	rs301791	0.449	RERE	RERE_2_gene	0.069664	0.0986	0.48004	0.70631	0.00e+00	1
PARK7	rs301791	1.000	RERE	RERE_2_gene	-0.008524	0.0770	0.91186	-0.11070	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_2_gene	0.039090	0.0935	0.67578	0.41827	0.00e+00	1
ENO1	rs301791	0.999	RERE	RERE_3_gene	-0.143351	0.1350	0.28854	-1.06148	0.00e+00	1
ERRFI1	rs301791	0.449	RERE	RERE_3_gene	0.081638	0.1286	0.52569	0.63466	0.00e+00	1
PARK7	rs301791	1.000	RERE	RERE_3_gene	0.010343	0.1004	0.91797	0.10299	0.00e+00	1
RERE	rs301791	0.657	RERE	RERE_3_gene	0.060026	0.1219	0.62240	0.49250	0.00e+00	1
BAZ2A	rs324015	0.629	STAT6	STAT6_1_gene	0.059988	0.1121	0.59250	0.53527	0.00e+00	1
DCTN2	rs324015	0.984	STAT6	STAT6_1_gene	-0.026900	0.1102	0.80709	-0.24420	0.00e+00	1
DDIT3	rs324015	0.594	STAT6	STAT6_1_gene	-0.296958	0.3876	0.44369	-0.76606	0.00e+00	1
KIF5A	rs324015	0.111	STAT6	STAT6_1_gene	-0.167899	0.1339	0.21005	-1.25364	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_1_gene	-0.035356	0.1238	0.77528	-0.28550	0.00e+00	1
MARS	rs324015	0.764	STAT6	STAT6_1_gene	0.078862	0.1334	0.55457	0.59098	0.00e+00	1
MBD6	rs324015	0.267	STAT6	STAT6_1_gene	0.037883	0.1145	0.74068	0.33098	0.00e+00	1
NAB2	rs324015	0.439	STAT6	STAT6_1_gene	0.030111	0.1350	0.82358	0.22296	0.00e+00	1
NACA	rs324015	1.000	STAT6	STAT6_1_gene	-0.045598	0.0739	0.53705	-0.61734	0.00e+00	1
PIP4K2C	rs324015	0.147	STAT6	STAT6_1_gene	-0.124065	0.1131	0.27287	-1.09664	1.39e-17	1
PRIM1	rs324015	0.389	STAT6	STAT6_1_gene	0.161141	0.1335	0.22735	1.20740	0.00e+00	1
PTGES3	rs324015	0.998	STAT6	STAT6_1_gene	-0.091375	0.1177	0.43764	-0.77627	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_1_gene	-0.147677	0.1183	0.21212	-1.24797	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_1_gene	-0.028682	0.2159	0.89431	-0.13287	-3.47e-18	1
ZBTB39	rs324015	0.223	STAT6	STAT6_1_gene	-0.062310	0.1117	0.57684	-0.55805	0.00e+00	1
BAZ2A	rs324015	0.629	STAT6	STAT6_2_gene	0.080456	0.0930	0.38702	0.86514	0.00e+00	1
DCTN2	rs324015	0.984	STAT6	STAT6_2_gene	-0.023893	0.0914	0.79382	-0.26137	0.00e+00	1
DDIT3	rs324015	0.594	STAT6	STAT6_2_gene	-0.029366	0.3217	0.92728	-0.09128	3.47e-18	1
KIF5A	rs324015	0.111	STAT6	STAT6_2_gene	0.100770	0.1112	0.36469	0.90657	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_2_gene	0.074952	0.1028	0.46582	0.72937	0.00e+00	1
MARS	rs324015	0.764	STAT6	STAT6_2_gene	-0.000984	0.1107	0.99291	-0.00889	0.00e+00	1
MBD6	rs324015	0.267	STAT6	STAT6_2_gene	0.010897	0.0950	0.90867	0.11472	0.00e+00	1
NAB2	rs324015	0.439	STAT6	STAT6_2_gene	0.030190	0.1121	0.78765	0.26938	0.00e+00	1
NACA	rs324015	1.000	STAT6	STAT6_2_gene	0.055119	0.0613	0.36856	0.89929	0.00e+00	1
PIP4K2C	rs324015	0.147	STAT6	STAT6_2_gene	0.013673	0.0939	0.88424	0.14561	0.00e+00	1
PRIM1	rs324015	0.389	STAT6	STAT6_2_gene	-0.007907	0.1108	0.94310	-0.07137	0.00e+00	1
PTGES3	rs324015	0.998	STAT6	STAT6_2_gene	0.126727	0.0977	0.19454	1.29749	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_2_gene	-0.016339	0.0982	0.86789	-0.16635	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_2_gene	0.334109	0.1791	0.06213	1.86590	0.00e+00	1
ZBTB39	rs324015	0.223	STAT6	STAT6_2_gene	-0.097349	0.0927	0.29346	-1.05071	0.00e+00	1
BAZ2A	rs324015	0.629	STAT6	STAT6_3_gene	-0.128238	0.0873	0.14175	-1.46961	0.00e+00	1
DCTN2	rs324015	0.984	STAT6	STAT6_3_gene	-0.003940	0.0858	0.96337	-0.04592	0.00e+00	1
DDIT3	rs324015	0.594	STAT6	STAT6_3_gene	-0.407738	0.3019	0.17684	-1.35080	0.00e+00	1
KIF5A	rs324015	0.111	STAT6	STAT6_3_gene	0.130491	0.1043	0.21099	1.25106	0.00e+00	1
LRP1	rs324015	0.342	STAT6	STAT6_3_gene	0.003193	0.0964	0.97359	0.03311	4.34e-19	1
MARS	rs324015	0.764	STAT6	STAT6_3_gene	-0.119747	0.1039	0.24924	-1.15237	0.00e+00	1
MBD6	rs324015	0.267	STAT6	STAT6_3_gene	0.028882	0.0891	0.74596	0.32400	0.00e+00	1
NAB2	rs324015	0.439	STAT6	STAT6_3_gene	-0.033556	0.1052	0.74971	-0.31905	0.00e+00	1
NACA	rs324015	1.000	STAT6	STAT6_3_gene	0.063065	0.0575	0.27295	1.09646	0.00e+00	1
PIP4K2C	rs324015	0.147	STAT6	STAT6_3_gene	0.056221	0.0881	0.52350	0.63803	0.00e+00	1
PRIM1	rs324015	0.389	STAT6	STAT6_3_gene	0.160709	0.1039	0.12210	1.54637	0.00e+00	1
PTGES3	rs324015	0.998	STAT6	STAT6_3_gene	0.111047	0.0917	0.22579	1.21147	0.00e+00	1
R3HDM2	rs324015	0.216	STAT6	STAT6_3_gene	-0.020534	0.0922	0.82373	-0.22277	0.00e+00	1
SHMT2	rs324015	0.813	STAT6	STAT6_3_gene	-0.211997	0.1681	0.20730	-1.26125	-2.78e-17	1
ZBTB39	rs324015	0.223	STAT6	STAT6_3_gene	0.004667	0.0870	0.95721	0.05366	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_1_gene	0.378321	0.3877	0.32920	0.97586	0.00e+00	1
GOLGA4	rs9882911	0.696	TRANK1	TRANK1_1_gene	-0.269217	0.3912	0.49141	-0.68814	0.00e+00	1
LRRFIP2	rs9882911	0.589	TRANK1	TRANK1_1_gene	-0.075324	0.3939	0.84835	-0.19124	0.00e+00	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_1_gene	0.100513	0.3614	0.78095	0.27810	0.00e+00	1
STAC	rs9882911	0.156	TRANK1	TRANK1_1_gene	-0.127235	0.4072	0.75468	-0.31249	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_2_gene	-0.060800	0.1590	0.70227	-0.38229	0.00e+00	1
GOLGA4	rs9882911	0.696	TRANK1	TRANK1_2_gene	-0.142900	0.1605	0.37325	-0.89051	0.00e+00	1
LRRFIP2	rs9882911	0.589	TRANK1	TRANK1_2_gene	-0.005953	0.1616	0.97061	-0.03685	8.67e-19	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_2_gene	-0.148094	0.1482	0.31784	-0.99903	0.00e+00	1
STAC	rs9882911	0.156	TRANK1	TRANK1_2_gene	0.148791	0.1670	0.37300	0.89097	0.00e+00	1
EPM2AIP1	rs9882911	0.478	TRANK1	TRANK1_3_gene	-0.046958	0.0735	0.52277	-0.63914	0.00e+00	1
GOLGA4	rs9882911	0.696	TRANK1	TRANK1_3_gene	-0.138966	0.0741	0.06084	-1.87520	0.00e+00	1
LRRFIP2	rs9882911	0.589	TRANK1	TRANK1_3_gene	0.083553	0.0746	0.26296	1.11960	0.00e+00	1
MLH1	rs9882911	0.716	TRANK1	TRANK1_3_gene	-0.062232	0.0685	0.36358	-0.90868	0.00e+00	1
STAC	rs9882911	0.156	TRANK1	TRANK1_3_gene	0.073905	0.0771	0.33816	0.95794	0.00e+00	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_1_gene	0.139057	0.1763	0.43023	0.78888	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_1_gene	-0.051945	0.1260	0.68011	-0.41235	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_1_gene	0.198498	0.1516	0.19058	1.30911	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_1_gene	-0.200493	0.1450	0.16683	-1.38275	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_1_gene	0.203254	0.1481	0.17014	1.37203	2.78e-17	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_2_gene	-0.084310	0.2354	0.72019	-0.35823	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_2_gene	0.062235	0.1682	0.71138	0.37004	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_2_gene	0.259209	0.2024	0.20047	1.28045	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_2_gene	0.508612	0.1935	0.00859	2.62916	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_2_gene	-0.224330	0.1978	0.25681	-1.13415	2.78e-17	1
NMB	rs11633075	0.289	UBE2Q2P1	UBE2Q2P1_3_gene	0.093799	0.1925	0.62605	0.48733	0.00e+00	1
SEC11A	rs11633075	0.998	UBE2Q2P1	UBE2Q2P1_3_gene	0.018460	0.1375	0.89325	0.13421	0.00e+00	1
WDR73	rs11633075	0.783	UBE2Q2P1	UBE2Q2P1_3_gene	-0.009724	0.1656	0.95318	-0.05872	0.00e+00	1
ZNF592	rs11633075	0.269	UBE2Q2P1	UBE2Q2P1_3_gene	-0.130917	0.1583	0.40841	-0.82680	0.00e+00	1
ZSCAN2	rs11633075	0.244	UBE2Q2P1	UBE2Q2P1_3_gene	-0.090456	0.1618	0.57612	-0.55911	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_1_gene	-0.252057	0.2245	0.26156	-1.12288	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_1_gene	-0.206613	0.1513	0.17211	-1.36572	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_1_gene	-0.243815	0.1725	0.15756	-1.41360	0.00e+00	1
C1orf54	rs2027349	0.187	VPS45	VPS45_1_gene	0.048377	0.1964	0.80541	0.24637	0.00e+00	1
CA14	rs2027349	0.138	VPS45	VPS45_1_gene	0.095599	0.1824	0.60032	0.52398	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_1_gene	-0.020033	0.1782	0.91049	-0.11243	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_1_gene	0.075822	0.2786	0.78551	0.27216	0.00e+00	1
MRPS21	rs2027349	0.992	VPS45	VPS45_1_gene	0.155979	0.1487	0.29429	1.04891	0.00e+00	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_1_gene	0.261521	0.1641	0.11099	1.59412	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_1_gene	-0.117106	0.1762	0.50629	-0.66469	0.00e+00	1
PRPF3	rs2027349	0.463	VPS45	VPS45_1_gene	0.041987	0.1683	0.80302	0.24946	0.00e+00	1
RPRD2	rs2027349	0.379	VPS45	VPS45_1_gene	-0.118599	0.1671	0.47783	-0.70986	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_1_gene	-0.047683	0.1630	0.76983	-0.29261	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_1_gene	0.072066	0.1687	0.66935	0.42708	0.00e+00	1
TARS2	rs2027349	0.278	VPS45	VPS45_1_gene	0.169332	0.1618	0.29524	1.04684	0.00e+00	1
VPS45	rs2027349	0.492	VPS45	VPS45_1_gene	-0.043631	0.1614	0.78688	-0.27038	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_2_gene	0.088746	0.0894	0.32119	0.99215	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_2_gene	0.109603	0.0603	0.06906	1.81854	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_2_gene	0.109935	0.0687	0.10974	1.59973	1.39e-17	1
C1orf54	rs2027349	0.187	VPS45	VPS45_2_gene	-0.017678	0.0782	0.82126	-0.22594	0.00e+00	1
CA14	rs2027349	0.138	VPS45	VPS45_2_gene	0.044225	0.0727	0.54300	0.60833	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_2_gene	0.084476	0.0710	0.23413	1.18998	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_2_gene	-0.124238	0.1110	0.26307	-1.11935	-1.39e-17	1
MRPS21	rs2027349	0.992	VPS45	VPS45_2_gene	-0.010742	0.0593	0.85618	-0.18125	0.00e+00	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_2_gene	-0.034524	0.0654	0.59754	-0.52798	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_2_gene	0.000727	0.0702	0.99174	0.01036	0.00e+00	1
PRPF3	rs2027349	0.463	VPS45	VPS45_2_gene	0.119294	0.0670	0.07524	1.77950	0.00e+00	1
RPRD2	rs2027349	0.379	VPS45	VPS45_2_gene	-0.012921	0.0666	0.84612	-0.19409	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_2_gene	-0.076907	0.0649	0.23624	-1.18464	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_2_gene	-0.038630	0.0672	0.56563	-0.57454	0.00e+00	1
TARS2	rs2027349	0.278	VPS45	VPS45_2_gene	-0.050281	0.0645	0.43540	-0.78006	0.00e+00	1
VPS45	rs2027349	0.492	VPS45	VPS45_2_gene	-0.022299	0.0643	0.72876	-0.34680	0.00e+00	1
ANP32E	rs2027349	0.874	VPS45	VPS45_3_gene	0.194891	0.2277	0.39218	0.85578	0.00e+00	1
APH1A	rs2027349	0.904	VPS45	VPS45_3_gene	0.144290	0.1535	0.34726	0.94004	0.00e+00	1
BOLA1	rs2027349	0.182	VPS45	VPS45_3_gene	-0.114827	0.1750	0.51179	-0.65612	0.00e+00	1
C1orf54	rs2027349	0.187	VPS45	VPS45_3_gene	-0.234163	0.1992	0.23977	-1.17574	-2.78e-17	1
CA14	rs2027349	0.138	VPS45	VPS45_3_gene	0.052518	0.1851	0.77663	0.28374	0.00e+00	1
HIST2H2AC	rs2027349	0.232	VPS45	VPS45_3_gene	0.286018	0.1807	0.11356	1.58277	0.00e+00	1
HIST2H2BE	rs2027349	0.200	VPS45	VPS45_3_gene	-0.435798	0.2825	0.12305	-1.54246	-5.55e-17	1
MRPS21	rs2027349	0.992	VPS45	VPS45_3_gene	0.058538	0.1509	0.69805	0.38799	0.00e+00	1
OTUD7B	rs2027349	0.237	VPS45	VPS45_3_gene	-0.113551	0.1665	0.49522	-0.68210	0.00e+00	1
PLEKHO1	rs2027349	0.822	VPS45	VPS45_3_gene	0.078146	0.1787	0.66198	0.43721	0.00e+00	1
PRPF3	rs2027349	0.463	VPS45	VPS45_3_gene	-0.021609	0.1707	0.89930	-0.12656	0.00e+00	1
RPRD2	rs2027349	0.379	VPS45	VPS45_3_gene	-0.010991	0.1695	0.94830	-0.06485	0.00e+00	1
SF3B4	rs2027349	0.915	VPS45	VPS45_3_gene	-0.147333	0.1653	0.37281	-0.89133	0.00e+00	1
SV2A	rs2027349	0.350	VPS45	VPS45_3_gene	0.326101	0.1711	0.05674	1.90591	0.00e+00	1
TARS2	rs2027349	0.278	VPS45	VPS45_3_gene	0.238844	0.1641	0.14555	1.45573	2.78e-17	1
VPS45	rs2027349	0.492	VPS45	VPS45_3_gene	-0.208142	0.1637	0.20355	-1.27173	2.78e-17	1

ash estimated mixture proportions and corresponding intervals:

pi	interval_a	interval_b
1	0	0

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