Guided Sparse Factor Analysis Project

– In-house scripts

Simulation study

• Simulation and GSFA run;
  
• Normal scenario results
  
• Count-based scenario results

LUHMES neural progenitor CROP-seq study

• Preprocessing of LUHMES CROP-seq data;
  
• GSFA application on processed CROP-seq data;
  
• GSFA result interpretation;
  
• Alternative differential expression methods;
  
• Permutation results.

Primary human CD8+ T cell CROP-seq study

• Preprocessing of T cell CROP-seq data;
  
• GSFA application on processed CROP-seq data;
  
• GSFA result interpretation;
• Alternative differential expression methods;
  
• Permutation results.